Mus musculus

40 known processes

Pinx1

PIN2/TERF1 interacting, telomerase inhibitor 1

(Aliases: 2610028A01Rik,2210403I16Rik,LPTS,AU024023,67-11-3,MGC144540,LPTS1)

Pinx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.133
nuclear division GO:0000280 158 0.132
dna endoreduplication GO:0042023 4 0.114
negative regulation of cell cycle GO:0045786 123 0.103
regulation of mitotic cell cycle GO:0007346 126 0.098
positive regulation of apoptotic process GO:0043065 217 0.093
regulation of cell cycle GO:0051726 281 0.089
amine metabolic process GO:0009308 45 0.087
mitotic cell cycle GO:0000278 195 0.074
organelle fission GO:0048285 170 0.073
positive regulation of cell death GO:0010942 224 0.072
cellular amino acid metabolic process GO:0006520 103 0.072
positive regulation of programmed cell death GO:0043068 218 0.069
regulation of cell cycle process GO:0010564 160 0.065
regulation of organelle organization GO:0033043 289 0.064
negative regulation of mitotic cell cycle GO:0045930 58 0.062
regulation of cellular amine metabolic process GO:0033238 20 0.060
regulation of cellular catabolic process GO:0031329 242 0.059
striated muscle tissue development GO:0014706 293 0.058
mitotic cell cycle process GO:1903047 159 0.057
regulation of cellular amino acid metabolic process GO:0006521 5 0.054
muscle tissue development GO:0060537 308 0.053
germ cell development GO:0007281 185 0.052
macromolecule catabolic process GO:0009057 281 0.052
cellular ketone metabolic process GO:0042180 84 0.049
dna replication GO:0006260 52 0.048
microtubule cytoskeleton organization GO:0000226 157 0.048
cellular amine metabolic process GO:0044106 44 0.048
regulation of exit from mitosis GO:0007096 1 0.047
meiotic cell cycle GO:0051321 122 0.047
microtubule based process GO:0007017 236 0.045
chromatin organization GO:0006325 206 0.044
muscle cell differentiation GO:0042692 261 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
negative regulation of dna replication GO:0008156 4 0.040
Zebrafish
regulation of cellular ketone metabolic process GO:0010565 66 0.040
oxidation reduction process GO:0055114 342 0.040
leukocyte differentiation GO:0002521 342 0.039
regulation of kinase activity GO:0043549 249 0.039
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
hematopoietic progenitor cell differentiation GO:0002244 143 0.039
regulation of protein localization GO:0032880 231 0.038
apoptotic signaling pathway GO:0097190 306 0.037
cellular response to gamma radiation GO:0071480 4 0.036
reactive oxygen species metabolic process GO:0072593 84 0.035
regulation of transferase activity GO:0051338 263 0.035
Zebrafish
negative regulation of molecular function GO:0044092 258 0.034
Zebrafish
protein processing GO:0016485 163 0.034
rna processing GO:0006396 105 0.034
cell division GO:0051301 120 0.033
camera type eye development GO:0043010 266 0.031
response to radiation GO:0009314 165 0.031
regulation of proteolysis GO:0030162 164 0.031
negative regulation of protein metabolic process GO:0051248 282 0.030
negative regulation of protein modification process GO:0031400 163 0.030
protein maturation GO:0051604 176 0.029
negative regulation of phosphorus metabolic process GO:0010563 184 0.029
cation transport GO:0006812 399 0.029
chromatin modification GO:0016568 187 0.029
regulation of cell cycle phase transition GO:1901987 77 0.028
response to organonitrogen compound GO:0010243 246 0.028
cellular homeostasis GO:0019725 240 0.027
mitotic nuclear division GO:0007067 48 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
g1 s transition of mitotic cell cycle GO:0000082 57 0.026
cellular response to dna damage stimulus GO:0006974 207 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
intrinsic apoptotic signaling pathway GO:0097193 132 0.025
meiotic nuclear division GO:0007126 115 0.025
gene silencing GO:0016458 38 0.025
signal transduction by p53 class mediator GO:0072331 51 0.024
cation homeostasis GO:0055080 212 0.024
regulation of cellular response to stress GO:0080135 159 0.024
skeletal muscle organ development GO:0060538 163 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
mitotic cell cycle checkpoint GO:0007093 31 0.024
regulation of neuron differentiation GO:0045664 281 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
maintenance of location GO:0051235 89 0.024
organelle assembly GO:0070925 177 0.024
regulation of chromosome organization GO:0033044 83 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
regulation of hydrolase activity GO:0051336 246 0.023
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.023
skeletal system development GO:0001501 356 0.023
retina development in camera type eye GO:0060041 119 0.023
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
cellular response to acid chemical GO:0071229 68 0.023
male gamete generation GO:0048232 285 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
cell type specific apoptotic process GO:0097285 268 0.022
telencephalon development GO:0021537 186 0.022
multicellular organismal homeostasis GO:0048871 164 0.022
response to drug GO:0042493 75 0.022
generation of precursor metabolites and energy GO:0006091 103 0.021
cytoplasmic transport GO:0016482 234 0.021
regulation of protein maturation GO:1903317 96 0.021
cytokine production GO:0001816 319 0.021
response to light stimulus GO:0009416 135 0.021
cell maturation GO:0048469 127 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
b cell activation GO:0042113 161 0.021
female gamete generation GO:0007292 74 0.021
regulation of membrane potential GO:0042391 192 0.021
regulation of cell activation GO:0050865 289 0.020
peptidyl amino acid modification GO:0018193 336 0.020
heterocycle catabolic process GO:0046700 280 0.020
chromosome segregation GO:0007059 48 0.020
cell cycle checkpoint GO:0000075 47 0.020
response to acid chemical GO:0001101 111 0.020
regulation of leukocyte differentiation GO:1902105 159 0.020
regulation of nuclear division GO:0051783 56 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
positive regulation of growth GO:0045927 104 0.019
gland development GO:0048732 330 0.019
cell growth GO:0016049 130 0.019
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.019
respiratory system development GO:0060541 190 0.019
regulation of binding GO:0051098 111 0.019
neuron death GO:0070997 154 0.019
cellular chemical homeostasis GO:0055082 215 0.019
regulation of cell division GO:0051302 76 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
spermatogenesis GO:0007283 284 0.019
transmembrane transport GO:0055085 412 0.019
striated muscle cell development GO:0055002 125 0.019
glycosyl compound metabolic process GO:1901657 246 0.018
mitotic cell cycle arrest GO:0071850 4 0.018
response to oxygen levels GO:0070482 62 0.018
regulation of protein kinase activity GO:0045859 232 0.018
stem cell differentiation GO:0048863 268 0.018
regulation of multi organism process GO:0043900 111 0.018
homeostasis of number of cells GO:0048872 210 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
regulation of reactive oxygen species metabolic process GO:2000377 40 0.018
cell adhesion GO:0007155 329 0.018
negative regulation of growth GO:0045926 99 0.018
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
histone modification GO:0016570 159 0.017
methylation GO:0032259 134 0.017
myeloid cell differentiation GO:0030099 233 0.017
regulation of anatomical structure size GO:0090066 178 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
forebrain development GO:0030900 302 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
regulation of mitotic cell cycle phase transition GO:1901990 73 0.017
regulation of cell growth GO:0001558 91 0.017
positive regulation of cell cycle GO:0045787 92 0.017
macromolecule methylation GO:0043414 120 0.017
response to organic cyclic compound GO:0014070 198 0.017
nuclear transport GO:0051169 139 0.017
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.017
regulation of secretion by cell GO:1903530 249 0.017
cell cycle g1 s phase transition GO:0044843 57 0.017
cell cycle switching GO:0060184 1 0.017
muscle cell development GO:0055001 133 0.017
ncrna processing GO:0034470 26 0.016
anatomical structure homeostasis GO:0060249 145 0.016
lymphocyte differentiation GO:0030098 242 0.016
cellular ion homeostasis GO:0006873 165 0.016
maturation of lsu rrna GO:0000470 1 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
regulation of cytokine production GO:0001817 266 0.016
cell aging GO:0007569 35 0.016
positive regulation of organelle organization GO:0010638 128 0.016
rhythmic process GO:0048511 174 0.016
dna integrity checkpoint GO:0031570 28 0.016
regulation of secretion GO:0051046 274 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
multi multicellular organism process GO:0044706 109 0.016
regulation of protein processing GO:0070613 96 0.016
cellular response to lipid GO:0071396 145 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
nitrogen compound transport GO:0071705 271 0.016
erythrocyte differentiation GO:0030218 88 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
response to peptide GO:1901652 136 0.015
regulation of defense response GO:0031347 233 0.015
negative regulation of immune system process GO:0002683 209 0.015
inflammatory response GO:0006954 244 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
regulation of myeloid leukocyte differentiation GO:0002761 58 0.015
ossification GO:0001503 216 0.015
t cell differentiation in thymus GO:0033077 77 0.015
chromosome organization involved in meiosis GO:0070192 39 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
regulation of protein catabolic process GO:0042176 108 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
regulation of cellular component size GO:0032535 121 0.015
cellular lipid metabolic process GO:0044255 323 0.015
cleavage involved in rrna processing GO:0000469 1 0.015
sequestering of metal ion GO:0051238 19 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
protein localization to organelle GO:0033365 185 0.015
multicellular organismal signaling GO:0035637 91 0.015
positive regulation of kinase activity GO:0033674 155 0.015
negative regulation of protein processing GO:0010955 79 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
negative regulation of proteolysis GO:0045861 74 0.015
oogenesis GO:0048477 56 0.015
sequestering of calcium ion GO:0051208 18 0.015
immune effector process GO:0002252 321 0.015
fertilization GO:0009566 127 0.015
epithelial cell development GO:0002064 159 0.015
spindle assembly involved in mitosis GO:0090307 4 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
actin cytoskeleton organization GO:0030036 220 0.014
mrna processing GO:0006397 63 0.014
response to decreased oxygen levels GO:0036293 59 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
response to inorganic substance GO:0010035 96 0.014
divalent metal ion transport GO:0070838 172 0.014
ion transmembrane transport GO:0034220 361 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
action potential GO:0001508 78 0.014
response to x ray GO:0010165 11 0.014
intracellular protein transport GO:0006886 204 0.014
intra s dna damage checkpoint GO:0031573 4 0.014
blood vessel morphogenesis GO:0048514 285 0.014
dna packaging GO:0006323 30 0.014
positive regulation of keratinocyte proliferation GO:0010838 4 0.014
regulation of organ morphogenesis GO:2000027 144 0.014
myosin filament assembly GO:0031034 2 0.014
dna damage checkpoint GO:0000077 26 0.014
regulation of cell migration GO:0030334 219 0.014
signal transduction involved in dna damage checkpoint GO:0072422 3 0.014
response to oxidative stress GO:0006979 123 0.014
epithelial cell proliferation GO:0050673 174 0.014
sensory perception GO:0007600 245 0.014
positive regulation of cellular respiration GO:1901857 3 0.014
regulation of mapk cascade GO:0043408 248 0.014
blastocyst development GO:0001824 80 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.013
protein dna complex subunit organization GO:0071824 28 0.013
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.013
reciprocal dna recombination GO:0035825 16 0.013
divalent inorganic cation transport GO:0072511 178 0.013
response to hypoxia GO:0001666 58 0.013
regulation of peptidase activity GO:0052547 96 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
negative regulation of cell cycle process GO:0010948 69 0.013
locomotory behavior GO:0007626 195 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
telomere capping GO:0016233 4 0.013
mitochondrion organization GO:0007005 134 0.013
angiogenesis GO:0001525 201 0.013
regulation of homeostatic process GO:0032844 182 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.013
regulation of protein transport GO:0051223 163 0.013
myeloid cell homeostasis GO:0002262 114 0.013
cellular response to external stimulus GO:0071496 88 0.013
dna dependent dna replication GO:0006261 24 0.013
positive regulation of proteolysis GO:0045862 85 0.013
regulation of t cell activation GO:0050863 170 0.013
transmission of nerve impulse GO:0019226 76 0.013
leukocyte apoptotic process GO:0071887 71 0.013
regulation of dna replication GO:0006275 17 0.013
Zebrafish
lymphocyte proliferation GO:0046651 164 0.013
aromatic compound catabolic process GO:0019439 286 0.013
negative regulation of cell cycle phase transition GO:1901988 48 0.013
sensory organ morphogenesis GO:0090596 242 0.013
protein catabolic process GO:0030163 221 0.013
developmental maturation GO:0021700 193 0.013
protein import into nucleus GO:0006606 95 0.013
organelle localization GO:0051640 179 0.013
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.013
ribosome biogenesis GO:0042254 20 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
regulation of ion transport GO:0043269 215 0.013
intestinal epithelial structure maintenance GO:0060729 4 0.013
leukocyte proliferation GO:0070661 172 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
progesterone metabolic process GO:0042448 4 0.012
regulation of system process GO:0044057 200 0.012
purine containing compound metabolic process GO:0072521 311 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
positive regulation of striated muscle cell apoptotic process GO:0010663 3 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
negative regulation of protein maturation GO:1903318 79 0.012
covalent chromatin modification GO:0016569 163 0.012
cardiocyte differentiation GO:0035051 87 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.012
regulation of mitosis GO:0007088 29 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
regulation of muscle tissue development GO:1901861 97 0.012
notch signaling pathway GO:0007219 71 0.012
mrna metabolic process GO:0016071 84 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
respiratory tube development GO:0030323 167 0.012
negative regulation of chromosome organization GO:2001251 30 0.012
regulation of neuron death GO:1901214 134 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
regulation of ossification GO:0030278 112 0.012
cell cycle arrest GO:0007050 37 0.012
t cell differentiation GO:0030217 174 0.012
t cell proliferation GO:0042098 120 0.012
membrane organization GO:0061024 245 0.012
pallium development GO:0021543 120 0.012
tissue homeostasis GO:0001894 115 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
dephosphorylation GO:0016311 129 0.012
positive regulation of protein modification process GO:0031401 299 0.011
negative regulation of cellular catabolic process GO:0031330 47 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
lipid biosynthetic process GO:0008610 179 0.011
adaptive immune response GO:0002250 155 0.011
chemotaxis GO:0006935 247 0.011
cellular response to oxidative stress GO:0034599 76 0.011
gliogenesis GO:0042063 141 0.011
positive regulation of cardiac muscle cell apoptotic process GO:0010666 3 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
maturation of 5 8s rrna GO:0000460 1 0.011
rna splicing GO:0008380 54 0.011
viral gene expression GO:0019080 3 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
limb development GO:0060173 166 0.011
nucleoside metabolic process GO:0009116 246 0.011
embryonic limb morphogenesis GO:0030326 126 0.011
regionalization GO:0003002 337 0.011
negative regulation of mapk cascade GO:0043409 65 0.011
nucleotide metabolic process GO:0009117 332 0.011
negative regulation of protein catabolic process GO:0042177 36 0.011
stem cell maintenance GO:0019827 130 0.011
negative regulation of nervous system development GO:0051961 156 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
positive regulation of cytokine production GO:0001819 174 0.011
skeletal system morphogenesis GO:0048705 203 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
neuron apoptotic process GO:0051402 142 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
negative regulation of transferase activity GO:0051348 85 0.011
Zebrafish
regulation of cell motility GO:2000145 236 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
urogenital system development GO:0001655 261 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
meiotic cell cycle process GO:1903046 77 0.011
dna conformation change GO:0071103 37 0.011
negative regulation of cell development GO:0010721 169 0.010
carbohydrate homeostasis GO:0033500 128 0.010
ras protein signal transduction GO:0007265 77 0.010
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 1 0.010
dna repair GO:0006281 107 0.010
branching morphogenesis of an epithelial tube GO:0048754 159 0.010
negative regulation of kinase activity GO:0033673 81 0.010
small gtpase mediated signal transduction GO:0007264 97 0.010
positive regulation of cell development GO:0010720 237 0.010
maturation of ssu rrna GO:0030490 1 0.010
metaphase plate congression GO:0051310 2 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.010
b cell activation involved in immune response GO:0002312 50 0.010
attachment of spindle microtubules to kinetochore GO:0008608 4 0.010
regulation of cell size GO:0008361 72 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010

Pinx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.061
cancer DOID:162 0 0.061
organ system cancer DOID:0050686 0 0.045
gastrointestinal system cancer DOID:3119 0 0.017
eye disease DOID:5614 0 0.014
eye and adnexa disease DOID:1492 0 0.014
nervous system disease DOID:863 0 0.014
sensory system disease DOID:0050155 0 0.014
disease of anatomical entity DOID:7 0 0.014
hematologic cancer DOID:2531 0 0.014
immune system cancer DOID:0060083 0 0.014
intestinal cancer DOID:10155 0 0.012
large intestine cancer DOID:5672 0 0.012
disease of metabolism DOID:0014667 0 0.012
colorectal cancer DOID:9256 0 0.010
colon cancer DOID:219 0 0.010