Mus musculus

12 known processes

Gch1

GTP cyclohydrolase 1

(Aliases: GTPCH,GTP-CH,Gch)

Gch1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytokine production GO:0001816 319 0.422
regulation of cytokine production GO:0001817 266 0.256
innate immune response GO:0045087 157 0.149
cellular amino acid metabolic process GO:0006520 103 0.120
leukocyte differentiation GO:0002521 342 0.112
regulation of defense response GO:0031347 233 0.106
cellular response to lipopolysaccharide GO:0071222 77 0.100
regulation of cellular ketone metabolic process GO:0010565 66 0.099
t cell activation GO:0042110 289 0.097
response to molecule of bacterial origin GO:0002237 143 0.094
immune effector process GO:0002252 321 0.094
apoptotic signaling pathway GO:0097190 306 0.092
myeloid cell differentiation GO:0030099 233 0.089
organonitrogen compound biosynthetic process GO:1901566 192 0.084
amine metabolic process GO:0009308 45 0.084
negative regulation of molecular function GO:0044092 258 0.080
cellular ketone metabolic process GO:0042180 84 0.077
regulation of cellular amino acid metabolic process GO:0006521 5 0.076
heterocycle catabolic process GO:0046700 280 0.071
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.065
cellular response to molecule of bacterial origin GO:0071219 83 0.065
response to lipopolysaccharide GO:0032496 128 0.063
macromolecule catabolic process GO:0009057 281 0.063
cation transport GO:0006812 399 0.062
cellular nitrogen compound catabolic process GO:0044270 280 0.061
regulation of multi organism process GO:0043900 111 0.060
negative regulation of protein metabolic process GO:0051248 282 0.059
homeostasis of number of cells GO:0048872 210 0.059
cellular response to lipid GO:0071396 145 0.058
protein modification by small protein conjugation or removal GO:0070647 207 0.058
regulation of cellular catabolic process GO:0031329 242 0.057
immune response regulating signaling pathway GO:0002764 125 0.057
reactive oxygen species metabolic process GO:0072593 84 0.056
positive regulation of defense response GO:0031349 124 0.056
negative regulation of viral genome replication GO:0045071 10 0.056
negative regulation of phosphorus metabolic process GO:0010563 184 0.054
nucleobase containing small molecule metabolic process GO:0055086 352 0.054
cellular response to biotic stimulus GO:0071216 92 0.054
male gamete generation GO:0048232 285 0.054
protein ubiquitination GO:0016567 171 0.053
anion transport GO:0006820 177 0.051
positive regulation of innate immune response GO:0045089 80 0.050
interspecies interaction between organisms GO:0044419 83 0.050
regulation of apoptotic signaling pathway GO:2001233 197 0.050
positive regulation of cellular catabolic process GO:0031331 148 0.050
negative regulation of cellular protein metabolic process GO:0032269 247 0.049
i kappab kinase nf kappab signaling GO:0007249 85 0.049
regulation of interleukin 8 production GO:0032677 3 0.049
protein modification by small protein conjugation GO:0032446 187 0.049
lymphocyte mediated immunity GO:0002449 139 0.048
nitrogen compound transport GO:0071705 271 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
adaptive immune response GO:0002250 155 0.047
positive regulation of cellular amine metabolic process GO:0033240 5 0.047
t cell differentiation GO:0030217 174 0.046
organic cyclic compound catabolic process GO:1901361 295 0.045
leukocyte mediated immunity GO:0002443 174 0.045
cellular response to dna damage stimulus GO:0006974 207 0.044
immune response activating signal transduction GO:0002757 116 0.043
positive regulation of cytokine production GO:0001819 174 0.043
response to organonitrogen compound GO:0010243 246 0.043
interleukin 8 production GO:0032637 4 0.043
positive regulation of protein modification process GO:0031401 299 0.043
aromatic compound catabolic process GO:0019439 286 0.041
regulation of innate immune response GO:0045088 91 0.041
lipid biosynthetic process GO:0008610 179 0.039
purine containing compound metabolic process GO:0072521 311 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.039
negative regulation of cell proliferation GO:0008285 296 0.039
regulation of mapk cascade GO:0043408 248 0.039
cellular amine metabolic process GO:0044106 44 0.038
regulation of secretion GO:0051046 274 0.037
nucleoside phosphate catabolic process GO:1901292 222 0.037
oxidation reduction process GO:0055114 342 0.037
cellular lipid metabolic process GO:0044255 323 0.037
negative regulation of multi organism process GO:0043901 68 0.037
peptidyl amino acid modification GO:0018193 336 0.036
regulation of hydrolase activity GO:0051336 246 0.036
lymphocyte differentiation GO:0030098 242 0.035
organic anion transport GO:0015711 137 0.035
cellular macromolecule catabolic process GO:0044265 206 0.034
cell killing GO:0001906 67 0.034
regulation of cellular response to stress GO:0080135 159 0.034
ribonucleoside metabolic process GO:0009119 245 0.034
regulation of homeostatic process GO:0032844 182 0.034
spermatogenesis GO:0007283 284 0.034
ribonucleoside catabolic process GO:0042454 206 0.034
ribonucleoside triphosphate metabolic process GO:0009199 220 0.034
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.033
response to organic cyclic compound GO:0014070 198 0.033
purine ribonucleotide metabolic process GO:0009150 290 0.033
nucleotide metabolic process GO:0009117 332 0.033
carbohydrate derivative biosynthetic process GO:1901137 183 0.033
myeloid cell homeostasis GO:0002262 114 0.033
regulation of t cell activation GO:0050863 170 0.033
cellular protein catabolic process GO:0044257 155 0.032
positive regulation of protein phosphorylation GO:0001934 242 0.032
regulation of kinase activity GO:0043549 249 0.032
organic acid biosynthetic process GO:0016053 86 0.032
carbohydrate metabolic process GO:0005975 230 0.032
regulation of protein transport GO:0051223 163 0.031
regulation of proteolysis GO:0030162 164 0.031
cation homeostasis GO:0055080 212 0.031
regulation of transferase activity GO:0051338 263 0.031
negative regulation of immune system process GO:0002683 209 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
inflammatory response GO:0006954 244 0.031
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
leukocyte mediated cytotoxicity GO:0001909 62 0.030
purine nucleotide metabolic process GO:0006163 302 0.030
defense response to other organism GO:0098542 197 0.030
glycosyl compound catabolic process GO:1901658 206 0.030
skin development GO:0043588 220 0.030
cellular modified amino acid metabolic process GO:0006575 63 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
small molecule biosynthetic process GO:0044283 132 0.030
positive regulation of hydrolase activity GO:0051345 148 0.029
purine containing compound catabolic process GO:0072523 213 0.029
transmembrane transport GO:0055085 412 0.029
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.029
nucleoside metabolic process GO:0009116 246 0.028
activation of innate immune response GO:0002218 56 0.028
regulation of cell motility GO:2000145 236 0.028
regulation of lymphocyte activation GO:0051249 240 0.028
ion transmembrane transport GO:0034220 361 0.028
intrinsic apoptotic signaling pathway GO:0097193 132 0.028
fat cell differentiation GO:0045444 160 0.027
myeloid leukocyte differentiation GO:0002573 119 0.027
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
positive regulation of lymphocyte activation GO:0051251 140 0.027
response to radiation GO:0009314 165 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
leukocyte proliferation GO:0070661 172 0.026
nucleoside triphosphate catabolic process GO:0009143 205 0.026
positive regulation of apoptotic signaling pathway GO:2001235 95 0.025
organophosphate catabolic process GO:0046434 232 0.025
alpha beta t cell differentiation GO:0046632 69 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
pattern recognition receptor signaling pathway GO:0002221 47 0.025
carboxylic acid biosynthetic process GO:0046394 86 0.025
positive regulation of programmed cell death GO:0043068 218 0.025
defense response to bacterium GO:0042742 119 0.025
regulation of leukocyte differentiation GO:1902105 159 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
viral process GO:0016032 41 0.025
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.025
glycoprotein metabolic process GO:0009100 116 0.025
cellular homeostasis GO:0019725 240 0.024
extracellular matrix organization GO:0030198 147 0.024
activation of immune response GO:0002253 138 0.024
muscle tissue development GO:0060537 308 0.024
cellular ion homeostasis GO:0006873 165 0.024
mitochondrion organization GO:0007005 134 0.024
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.024
response to nutrient levels GO:0031667 109 0.023
response to extracellular stimulus GO:0009991 127 0.023
organophosphate biosynthetic process GO:0090407 122 0.023
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.023
respiratory system development GO:0060541 190 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.023
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.023
regulation of binding GO:0051098 111 0.023
cellular response to organonitrogen compound GO:0071417 145 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
cellular chemical homeostasis GO:0055082 215 0.022
regulation of lymphocyte proliferation GO:0050670 117 0.022
ossification GO:0001503 216 0.022
protein catabolic process GO:0030163 221 0.022
positive regulation of transferase activity GO:0051347 167 0.022
purine nucleoside catabolic process GO:0006152 205 0.022
cytoplasmic transport GO:0016482 234 0.022
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
sensory perception GO:0007600 245 0.021
regulation of response to wounding GO:1903034 189 0.021
metal ion homeostasis GO:0055065 189 0.021
ribonucleoside monophosphate metabolic process GO:0009161 80 0.021
regulation of cell migration GO:0030334 219 0.021
regulation of reactive oxygen species metabolic process GO:2000377 40 0.021
intracellular protein transport GO:0006886 204 0.021
modification dependent protein catabolic process GO:0019941 133 0.021
defense response to virus GO:0051607 68 0.021
compound eye development GO:0048749 1 0.020
germ cell development GO:0007281 185 0.020
response to inorganic substance GO:0010035 96 0.020
positive regulation of immune effector process GO:0002699 107 0.020
peptide metabolic process GO:0006518 46 0.020
negative regulation of protein phosphorylation GO:0001933 126 0.020
b cell activation GO:0042113 161 0.020
lymphocyte proliferation GO:0046651 164 0.020
cell type specific apoptotic process GO:0097285 268 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
protein import GO:0017038 101 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
nucleoside catabolic process GO:0009164 206 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.020
organic acid transport GO:0015849 101 0.020
regulation of leukocyte proliferation GO:0070663 121 0.020
cellular response to cytokine stimulus GO:0071345 189 0.019
steroid metabolic process GO:0008202 119 0.019
positive regulation of cell death GO:0010942 224 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
extracellular structure organization GO:0043062 148 0.019
leukocyte homeostasis GO:0001776 79 0.019
regulation of myeloid cell differentiation GO:0045637 96 0.019
regulation of map kinase activity GO:0043405 120 0.019
modification dependent macromolecule catabolic process GO:0043632 133 0.019
cell activation involved in immune response GO:0002263 126 0.019
monocarboxylic acid metabolic process GO:0032787 191 0.019
blood vessel morphogenesis GO:0048514 285 0.019
positive regulation of t cell activation GO:0050870 101 0.019
monosaccharide metabolic process GO:0005996 106 0.019
gland development GO:0048732 330 0.018
regulation of interferon gamma production GO:0032649 57 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
lung development GO:0030324 164 0.018
protein maturation GO:0051604 176 0.018
regulation of secretion by cell GO:1903530 249 0.018
respiratory tube development GO:0030323 167 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
nucleoside monophosphate metabolic process GO:0009123 85 0.018
placenta development GO:0001890 140 0.018
protein localization to organelle GO:0033365 185 0.017
epidermis development GO:0008544 187 0.017
glucose homeostasis GO:0042593 128 0.017
negative regulation of transferase activity GO:0051348 85 0.017
negative regulation of cytokine production GO:0001818 84 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
endocytosis GO:0006897 168 0.017
striated muscle tissue development GO:0014706 293 0.017
regulation of t cell proliferation GO:0042129 92 0.017
lymphocyte activation involved in immune response GO:0002285 93 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
negative regulation of hydrolase activity GO:0051346 71 0.017
regulation of cell killing GO:0031341 40 0.017
regulation of protein catabolic process GO:0042176 108 0.017
atp metabolic process GO:0046034 75 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
negative regulation of lymphocyte activation GO:0051250 91 0.017
translation GO:0006412 93 0.017
single organism cell adhesion GO:0098602 156 0.017
regulation of membrane potential GO:0042391 192 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
negative regulation of defense response GO:0031348 77 0.017
negative regulation of protein modification process GO:0031400 163 0.017
lateral inhibition GO:0046331 1 0.017
mapk cascade GO:0000165 281 0.016
membrane organization GO:0061024 245 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
regulation of ion transport GO:0043269 215 0.016
cellular amino acid biosynthetic process GO:0008652 22 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
regulation of hormone levels GO:0010817 211 0.016
purine nucleoside monophosphate metabolic process GO:0009126 81 0.016
regulation of cell activation GO:0050865 289 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
positive regulation of cell activation GO:0050867 158 0.016
antimicrobial peptide production GO:0002775 2 0.016
negative regulation of cell activation GO:0050866 111 0.016
response to peptide GO:1901652 136 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.016
alpha amino acid metabolic process GO:1901605 59 0.015
regulation of ossification GO:0030278 112 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
alpha beta t cell activation GO:0046631 91 0.015
cellular amide metabolic process GO:0043603 58 0.015
lipid transport GO:0006869 98 0.015
innate immune response activating signal transduction GO:0002758 50 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.015
positive regulation of nucleotide catabolic process GO:0030813 88 0.015
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
positive regulation of interleukin 8 production GO:0032757 2 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
positive regulation of kinase activity GO:0033674 155 0.015
endomembrane system organization GO:0010256 147 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
regulation of leukocyte mediated immunity GO:0002703 104 0.015
cytokine mediated signaling pathway GO:0019221 115 0.015
positive regulation of proteolysis GO:0045862 85 0.015
ear development GO:0043583 200 0.015
cholesterol metabolic process GO:0008203 56 0.015
response to ionizing radiation GO:0010212 42 0.015
dna metabolic process GO:0006259 303 0.015
amide transport GO:0042886 138 0.014
protein targeting GO:0006605 143 0.014
regulation of cytokine biosynthetic process GO:0042035 59 0.014
carbohydrate homeostasis GO:0033500 128 0.014
protein processing GO:0016485 163 0.014
regulation of cell cycle GO:0051726 281 0.014
regulation of leukocyte apoptotic process GO:2000106 56 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
skeletal muscle organ development GO:0060538 163 0.014
t cell activation involved in immune response GO:0002286 43 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
regulation of response to biotic stimulus GO:0002831 38 0.014
divalent inorganic cation transport GO:0072511 178 0.014
camera type eye development GO:0043010 266 0.014
skeletal system development GO:0001501 356 0.014
regulation of alpha beta t cell activation GO:0046634 53 0.014
nuclear transport GO:0051169 139 0.014
response to peptide hormone GO:0043434 127 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
regulation of lymphocyte differentiation GO:0045619 107 0.014
lymphocyte homeostasis GO:0002260 64 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
positive regulation of leukocyte differentiation GO:1902107 86 0.014
cellular modified amino acid biosynthetic process GO:0042398 12 0.014
spermatid differentiation GO:0048515 115 0.014
alcohol metabolic process GO:0006066 116 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
nuclear import GO:0051170 95 0.014
carboxylic acid transport GO:0046942 100 0.014
ras protein signal transduction GO:0007265 77 0.014
regulation of adaptive immune response GO:0002819 90 0.014
blood circulation GO:0008015 195 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
t cell mediated immunity GO:0002456 50 0.014
regulation of t cell differentiation GO:0045580 83 0.014
regulation of interleukin 6 production GO:0032675 55 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.014
negative regulation of interleukin 8 production GO:0032717 1 0.014
rhythmic process GO:0048511 174 0.014
cytokine metabolic process GO:0042107 71 0.014
cellular response to arsenic containing substance GO:0071243 4 0.013
maintenance of location GO:0051235 89 0.013
cytokine biosynthetic process GO:0042089 68 0.013
dendrite development GO:0016358 115 0.013
regulation of fat cell differentiation GO:0045598 81 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
cation transmembrane transport GO:0098655 266 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
mrna metabolic process GO:0016071 84 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
peptide transport GO:0015833 133 0.013
regulation of inflammatory response GO:0050727 147 0.013
negative regulation of inflammatory response GO:0050728 61 0.013
cytokine secretion GO:0050663 72 0.013
cellular response to peptide GO:1901653 92 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
natural killer cell mediated cytotoxicity GO:0042267 29 0.013
intracellular receptor signaling pathway GO:0030522 74 0.013
hormone secretion GO:0046879 128 0.013
negative regulation of immune effector process GO:0002698 55 0.013
response to endoplasmic reticulum stress GO:0034976 53 0.013
leukocyte apoptotic process GO:0071887 71 0.013
rna interference GO:0016246 2 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
regulation of protein kinase activity GO:0045859 232 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.013
wound healing GO:0042060 157 0.013
b cell differentiation GO:0030183 78 0.013
sequestering of metal ion GO:0051238 19 0.013
lipid localization GO:0010876 126 0.013
nucleotide catabolic process GO:0009166 217 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
protein import into nucleus GO:0006606 95 0.013
regulation of body fluid levels GO:0050878 162 0.013
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.013
forebrain development GO:0030900 302 0.013
apoptotic mitochondrial changes GO:0008637 48 0.013
regulation of myotube differentiation GO:0010830 62 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
atp catabolic process GO:0006200 55 0.012
regulation of organelle organization GO:0033043 289 0.012
response to oxygen radical GO:0000305 16 0.012
protein secretion GO:0009306 111 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
viral life cycle GO:0019058 36 0.012
multicellular organism growth GO:0035264 161 0.012
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.012
purine containing compound biosynthetic process GO:0072522 70 0.012
rna processing GO:0006396 105 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
neural tube development GO:0021915 160 0.012
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.012
cell maturation GO:0048469 127 0.012
amino acid transport GO:0006865 61 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
positive regulation of lymphocyte differentiation GO:0045621 61 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
connective tissue development GO:0061448 179 0.012
regionalization GO:0003002 337 0.012
synaptic transmission GO:0007268 329 0.012
protein localization to nucleus GO:0034504 121 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
negative regulation of cell cycle GO:0045786 123 0.012
interferon gamma production GO:0032609 67 0.012
sensory organ morphogenesis GO:0090596 242 0.012
sterol metabolic process GO:0016125 58 0.012
negative regulation of t cell activation GO:0050868 65 0.012
programmed necrotic cell death GO:0097300 28 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.012
cell adhesion GO:0007155 329 0.011
epithelial cell proliferation GO:0050673 174 0.011
protein oligomerization GO:0051259 67 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
sulfur compound metabolic process GO:0006790 100 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
phagocytosis GO:0006909 66 0.011
oocyte construction GO:0007308 2 0.011
negative regulation of viral process GO:0048525 23 0.011
interleukin 6 production GO:0032635 58 0.011
regulation of endocytosis GO:0030100 69 0.011
regulation of defense response to fungus GO:1900150 1 0.011
single organism nuclear import GO:1902593 95 0.011
natural killer cell mediated immunity GO:0002228 29 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
developmental maturation GO:0021700 193 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
angiogenesis GO:0001525 201 0.011
divalent metal ion transport GO:0070838 172 0.011
regulation of translation GO:0006417 71 0.011
muscle cell differentiation GO:0042692 261 0.011
response to acid chemical GO:0001101 111 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
fat soluble vitamin biosynthetic process GO:0042362 4 0.011
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.011
response to drug GO:0042493 75 0.011
regulation of peptide transport GO:0090087 91 0.011
regulation of peptidase activity GO:0052547 96 0.011
response to oxidative stress GO:0006979 123 0.011
positive regulation of nervous system development GO:0051962 221 0.011
sensory system development GO:0048880 3 0.011
stem cell differentiation GO:0048863 268 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
fatty acid metabolic process GO:0006631 121 0.011
response to oxygen levels GO:0070482 62 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
anion transmembrane transport GO:0098656 71 0.011
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
fertilization GO:0009566 127 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
regulation of defense response to bacterium GO:1900424 3 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
regulation of lipid biosynthetic process GO:0046890 54 0.011
spermatid development GO:0007286 108 0.011
positive regulation of atpase activity GO:0032781 3 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
negative regulation of binding GO:0051100 39 0.011
cellular response to insulin stimulus GO:0032869 78 0.011
oocyte axis specification GO:0007309 2 0.011
cellular response to amino acid stimulus GO:0071230 29 0.011
cellular response to external stimulus GO:0071496 88 0.011
response to insulin GO:0032868 100 0.011
positive regulation of protein kinase activity GO:0045860 144 0.010
production of molecular mediator of immune response GO:0002440 103 0.010
regulation of protein ubiquitination GO:0031396 52 0.010
sequestering of calcium ion GO:0051208 18 0.010
lipid homeostasis GO:0055088 63 0.010
circulatory system process GO:0003013 197 0.010
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.010
regulation of cell adhesion GO:0030155 154 0.010
rho protein signal transduction GO:0007266 32 0.010
calcium ion homeostasis GO:0055074 127 0.010
calcium ion transport GO:0006816 159 0.010
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.010
muscle system process GO:0003012 141 0.010
regulation of striated muscle cell differentiation GO:0051153 81 0.010
response to starvation GO:0042594 65 0.010
t cell proliferation GO:0042098 120 0.010
generation of precursor metabolites and energy GO:0006091 103 0.010
regulation of myeloid leukocyte differentiation GO:0002761 58 0.010
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.010
regulation of neuron differentiation GO:0045664 281 0.010
protein localization to membrane GO:0072657 108 0.010
neuron death GO:0070997 154 0.010

Gch1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.030
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
cancer DOID:162 0 0.023
immune system disease DOID:2914 0 0.017
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.016
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
organ system cancer DOID:0050686 0 0.014
central nervous system disease DOID:331 0 0.012
neuropathy DOID:870 0 0.010