Mus musculus

294 known processes

Epha4

Eph receptor A4

(Aliases: 2900005C20Rik,AI385584,Cek8,Hek8,Tyro1,Sek1,rb,Sek)

Epha4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rac gtpase activity GO:0032314 13 1.000
ephrin receptor signaling pathway GO:0048013 20 1.000
regulation of rho gtpase activity GO:0032319 58 1.000
negative chemotaxis GO:0050919 14 1.000
Mouse
central nervous system projection neuron axonogenesis GO:0021952 21 1.000
negative regulation of ovulation GO:0060280 1 1.000
Worm
regulation of ras gtpase activity GO:0032318 88 0.999
rho protein signal transduction GO:0007266 32 0.999
regulation of dendritic spine morphogenesis GO:0061001 17 0.997
guanosine containing compound catabolic process GO:1901069 144 0.996
ras protein signal transduction GO:0007265 77 0.994
regulation of ras protein signal transduction GO:0046578 114 0.994
guanosine containing compound metabolic process GO:1901068 144 0.994
dendritic spine development GO:0060996 30 0.994
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.993
Mouse
regulation of rac protein signal transduction GO:0035020 19 0.993
corpus callosum development GO:0022038 10 0.992
Mouse
gtp metabolic process GO:0046039 144 0.992
axonogenesis GO:0007409 274 0.991
rac protein signal transduction GO:0016601 13 0.991
central nervous system neuron axonogenesis GO:0021955 28 0.991
regulation of gtp catabolic process GO:0033124 113 0.991
regulation of nucleoside metabolic process GO:0009118 130 0.990
negative regulation of neuron projection development GO:0010977 50 0.988
axon guidance GO:0007411 141 0.987
regulation of cell projection organization GO:0031344 206 0.984
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.984
negative regulation of axon guidance GO:1902668 8 0.983
regulation of nucleotide catabolic process GO:0030811 122 0.983
purine nucleotide catabolic process GO:0006195 211 0.979
neuron recognition GO:0008038 25 0.978
regulation of purine nucleotide catabolic process GO:0033121 122 0.977
notochord formation GO:0014028 5 0.977
Mouse
nucleotide catabolic process GO:0009166 217 0.976
fasciculation of motor neuron axon GO:0097156 2 0.974
nucleoside catabolic process GO:0009164 206 0.973
motor neuron axon guidance GO:0008045 26 0.971
gtp catabolic process GO:0006184 143 0.971
regulation of neuron projection development GO:0010975 169 0.971
nucleoside triphosphate metabolic process GO:0009141 230 0.970
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.967
angiogenesis GO:0001525 201 0.966
Mouse
negative regulation of cell projection organization GO:0031345 56 0.966
fasciculation of sensory neuron axon GO:0097155 3 0.966
purine ribonucleoside catabolic process GO:0046130 205 0.964
pallium development GO:0021543 120 0.960
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.960
epithelial tube morphogenesis GO:0060562 303 0.960
Mouse
purine nucleotide metabolic process GO:0006163 302 0.959
regulation of nucleotide metabolic process GO:0006140 169 0.956
morphogenesis of a branching structure GO:0001763 203 0.955
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.955
locomotory behavior GO:0007626 195 0.953
ribonucleoside triphosphate catabolic process GO:0009203 199 0.953
regulation of rho protein signal transduction GO:0035023 71 0.952
purine ribonucleotide metabolic process GO:0009150 290 0.950
heterocycle catabolic process GO:0046700 280 0.949
telencephalon development GO:0021537 186 0.948
Mouse
ribonucleotide metabolic process GO:0009259 291 0.943
morphogenesis of a branching epithelium GO:0061138 193 0.942
Mouse
ribonucleoside catabolic process GO:0042454 206 0.941
ribonucleotide catabolic process GO:0009261 208 0.936
regulation of protein autophosphorylation GO:0031952 8 0.936
Mouse
regulation of vasculature development GO:1901342 88 0.934
Mouse
regulation of neuron differentiation GO:0045664 281 0.934
neuron projection guidance GO:0097485 141 0.933
forebrain development GO:0030900 302 0.933
Mouse
positive regulation of rho gtpase activity GO:0032321 41 0.932
Human
regulation of purine nucleotide metabolic process GO:1900542 169 0.931
negative regulation of dendrite development GO:2000171 9 0.930
small gtpase mediated signal transduction GO:0007264 97 0.930
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.930
nucleoside metabolic process GO:0009116 246 0.929
developmental maturation GO:0021700 193 0.928
Mouse Worm
retinal ganglion cell axon guidance GO:0031290 18 0.926
Mouse
peripheral nervous system development GO:0007422 53 0.925
Fly
aromatic compound catabolic process GO:0019439 286 0.925
ribonucleoside metabolic process GO:0009119 245 0.923
negative regulation of synapse assembly GO:0051964 3 0.916
Mouse
central nervous system neuron development GO:0021954 67 0.914
dendritic spine organization GO:0097061 26 0.908
epithelial cell migration GO:0010631 63 0.906
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.905
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.903
regulation of cell migration GO:0030334 219 0.898
Mouse
dendritic spine morphogenesis GO:0060997 22 0.898
cerebellar granule cell precursor tangential migration GO:0021935 1 0.897
purine nucleoside catabolic process GO:0006152 205 0.897
parathyroid hormone secretion GO:0035898 2 0.891
Mouse
glycosyl compound metabolic process GO:1901657 246 0.890
negative regulation of cell development GO:0010721 169 0.886
branching morphogenesis of an epithelial tube GO:0048754 159 0.884
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.883
cell recognition GO:0008037 83 0.883
neuron projection extension GO:1990138 64 0.880
ribonucleoside triphosphate metabolic process GO:0009199 220 0.869
organic cyclic compound catabolic process GO:1901361 295 0.862
nucleotide metabolic process GO:0009117 332 0.860
purine nucleoside triphosphate catabolic process GO:0009146 203 0.858
positive regulation of ras gtpase activity GO:0032320 65 0.853
Human
regulation of cellular catabolic process GO:0031329 242 0.850
nucleoside triphosphate catabolic process GO:0009143 205 0.848
regulation of actin cytoskeleton organization GO:0032956 84 0.837
Mouse
notochord cell development GO:0060035 1 0.835
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.834
glial cell differentiation GO:0010001 131 0.834
axial mesoderm formation GO:0048320 3 0.827
Mouse
chemotaxis GO:0006935 247 0.825
negative regulation of cellular component organization GO:0051129 194 0.819
glycosyl compound catabolic process GO:1901658 206 0.818
synapse organization GO:0050808 125 0.812
Mouse
embryonic organ morphogenesis GO:0048562 276 0.812
Mouse
ribose phosphate metabolic process GO:0019693 291 0.805
rap protein signal transduction GO:0032486 3 0.795
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.789
regulation of cell motility GO:2000145 236 0.788
Mouse
gland development GO:0048732 330 0.786
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.782
cell adhesion GO:0007155 329 0.780
Mouse
regulation of dendritic spine development GO:0060998 22 0.778
purine containing compound catabolic process GO:0072523 213 0.777
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.773
branching involved in salivary gland morphogenesis GO:0060445 26 0.772
cellular amino acid metabolic process GO:0006520 103 0.763
regulation of ovulation GO:0060278 3 0.761
Worm
epithelium migration GO:0090132 63 0.760
Mouse
central nervous system neuron differentiation GO:0021953 162 0.759
regulation of cell adhesion mediated by integrin GO:0033628 13 0.758
Mouse
regulation of endothelial cell migration GO:0010594 22 0.754
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.754
nucleoside phosphate metabolic process GO:0006753 338 0.754
cranial nerve development GO:0021545 41 0.754
Mouse
negative regulation of dendritic spine development GO:0061000 3 0.752
synaptic transmission GO:0007268 329 0.750
Mouse
regulation of rap protein signal transduction GO:0032487 6 0.743
appendage development GO:0048736 166 0.740
regulation of axon guidance GO:1902667 13 0.738
substrate dependent cell migration GO:0006929 18 0.736
Mouse
endothelial cell migration GO:0043542 44 0.735
Mouse
hippocampus development GO:0021766 52 0.724
Mouse
urogenital system development GO:0001655 261 0.719
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.713
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.700
positive regulation of gtpase activity GO:0043547 85 0.695
Human
regulation of rap gtpase activity GO:0032317 6 0.692
regulation of angiogenesis GO:0045765 81 0.688
Mouse
regulation of hydrolase activity GO:0051336 246 0.688
mitral valve morphogenesis GO:0003183 4 0.684
branchiomotor neuron axon guidance GO:0021785 7 0.684
carbohydrate derivative catabolic process GO:1901136 231 0.683
purine containing compound metabolic process GO:0072521 311 0.682
neural tube development GO:0021915 160 0.682
Mouse
limbic system development GO:0021761 72 0.680
Mouse
blood vessel morphogenesis GO:0048514 285 0.674
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.669
insulin secretion GO:0030073 89 0.668
Mouse
commissural neuron axon guidance GO:0071679 8 0.665
Mouse
stem cell differentiation GO:0048863 268 0.662
Mouse
single organismal cell cell adhesion GO:0016337 131 0.660
Mouse
positive regulation of map kinase activity GO:0043406 84 0.654
heart morphogenesis GO:0003007 178 0.648
Mouse
negative regulation of neuron projection regeneration GO:0070571 3 0.642
axon extension involved in axon guidance GO:0048846 14 0.638
positive regulation of protein phosphorylation GO:0001934 242 0.631
hindbrain development GO:0030902 128 0.629
neural precursor cell proliferation GO:0061351 121 0.627
Mouse
negative regulation of nervous system development GO:0051961 156 0.624
organophosphate catabolic process GO:0046434 232 0.613
regulation of cellular ketone metabolic process GO:0010565 66 0.608
regulation of peptide hormone secretion GO:0090276 75 0.601
Mouse
mapk cascade GO:0000165 281 0.601
axonal fasciculation GO:0007413 15 0.597
adult behavior GO:0030534 135 0.596
tissue migration GO:0090130 68 0.593
Mouse
mesenchymal cell differentiation GO:0048762 107 0.591
Mouse
positive regulation of cytoskeleton organization GO:0051495 49 0.589
Mouse
ear morphogenesis GO:0042471 118 0.588
Mouse
positive regulation of nervous system development GO:0051962 221 0.586
Mouse
cellular ketone metabolic process GO:0042180 84 0.581
regulation of neuronal synaptic plasticity GO:0048168 30 0.580
Mouse
sensory perception of temperature stimulus GO:0050951 9 0.577
Mouse
purine nucleoside metabolic process GO:0042278 241 0.575
negative regulation of axon extension GO:0030517 19 0.575
regulation of blood vessel endothelial cell migration GO:0043535 12 0.572
Mouse
mitral valve development GO:0003174 4 0.570
positive regulation of jnk cascade GO:0046330 46 0.569
positive regulation of protein kinase activity GO:0045860 144 0.566
semaphorin plexin signaling pathway involved in neuron projection guidance GO:1902285 6 0.566
positive regulation of nucleotide catabolic process GO:0030813 88 0.563
Human
anatomical structure arrangement GO:0048532 20 0.557
regulation of axon extension GO:0030516 43 0.555
trigeminal nerve morphogenesis GO:0021636 6 0.553
actin cytoskeleton organization GO:0030036 220 0.550
Mouse
cellular amine metabolic process GO:0044106 44 0.544
regulation of cellular amine metabolic process GO:0033238 20 0.539
salivary gland morphogenesis GO:0007435 33 0.539
positive regulation of gtp catabolic process GO:0033126 85 0.538
Human
adult walking behavior GO:0007628 41 0.537
cellular response to monosaccharide stimulus GO:0071326 47 0.533
Mouse
axial mesoderm development GO:0048318 8 0.533
Mouse
cell adhesion mediated by integrin GO:0033627 18 0.531
Mouse
axon target recognition GO:0007412 4 0.531
optic nerve development GO:0021554 8 0.531
Mouse
peptide transport GO:0015833 133 0.530
Mouse
dichotomous subdivision of terminal units involved in salivary gland branching GO:0060666 5 0.525
notochord development GO:0030903 20 0.523
Mouse
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.519
Mouse
adult locomotory behavior GO:0008344 91 0.518
positive regulation of neuron differentiation GO:0045666 141 0.510
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.508
forebrain neuron development GO:0021884 30 0.507
postganglionic parasympathetic nervous system development GO:0021784 2 0.504
blood vessel endothelial cell migration GO:0043534 23 0.504
Mouse
stem cell development GO:0048864 219 0.502
Mouse
ear development GO:0043583 200 0.497
Mouse
regulation of reproductive process GO:2000241 66 0.495
Worm
dendrite development GO:0016358 115 0.493
cellular response to hexose stimulus GO:0071331 47 0.491
Mouse
facial nerve structural organization GO:0021612 10 0.487
axial mesoderm morphogenesis GO:0048319 5 0.485
Mouse
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.482
Mouse
positive regulation of cell development GO:0010720 237 0.481
Mouse
positive regulation of mapk cascade GO:0043410 170 0.473
regulation of peptide secretion GO:0002791 77 0.472
Mouse
cognition GO:0050890 149 0.471
Mouse
regionalization GO:0003002 337 0.471
semaphorin plexin signaling pathway involved in axon guidance GO:1902287 6 0.469
formation of primary germ layer GO:0001704 77 0.466
Mouse
skeletal system development GO:0001501 356 0.455
Mouse
regulation of cardiac muscle tissue development GO:0055024 31 0.454
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.447
developmental cell growth GO:0048588 84 0.445
positive regulation of transferase activity GO:0051347 167 0.445
cell growth GO:0016049 130 0.444
embryonic epithelial tube formation GO:0001838 130 0.443
muscle cell differentiation GO:0042692 261 0.441
regulation of cellular component biogenesis GO:0044087 181 0.438
Mouse
regulation of actin filament based process GO:0032970 99 0.438
Mouse
regulation of astrocyte differentiation GO:0048710 20 0.438
camera type eye development GO:0043010 266 0.436
Mouse
regulation of hormone secretion GO:0046883 88 0.436
Mouse
corticospinal tract morphogenesis GO:0021957 6 0.434
positive regulation of striated muscle tissue development GO:0045844 31 0.427
sympathetic nervous system development GO:0048485 22 0.418
ameboidal type cell migration GO:0001667 128 0.416
Mouse
cellular chemical homeostasis GO:0055082 215 0.412
Mouse
regulation of cell adhesion GO:0030155 154 0.409
Mouse
inner ear morphogenesis GO:0042472 101 0.409
Mouse
regulation of protein kinase activity GO:0045859 232 0.408
lens morphogenesis in camera type eye GO:0002089 24 0.406
Mouse
neuron apoptotic process GO:0051402 142 0.401
Mouse
trunk neural crest cell migration GO:0036484 4 0.397
peptidyl tyrosine modification GO:0018212 145 0.395
actomyosin structure organization GO:0031032 56 0.392
Mouse
negative regulation of cell proliferation GO:0008285 296 0.392
positive regulation of cellular catabolic process GO:0031331 148 0.390
Human
regulation of synaptic plasticity GO:0048167 87 0.384
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.384
hindbrain tangential cell migration GO:0021934 2 0.383
regulation of cellular component size GO:0032535 121 0.381
regulation of mapk cascade GO:0043408 248 0.380
positive regulation of apoptotic process GO:0043065 217 0.380
Mouse
limb morphogenesis GO:0035108 149 0.379
ossification GO:0001503 216 0.377
Mouse
chemorepulsion of branchiomotor axon GO:0021793 1 0.377
anterior commissure morphogenesis GO:0021960 6 0.374
regulation of epithelial cell migration GO:0010632 35 0.372
Mouse
digestive tract morphogenesis GO:0048546 147 0.369
Mouse
neuron projection regeneration GO:0031102 14 0.368
regulation of map kinase activity GO:0043405 120 0.368
negative regulation of chemotaxis GO:0050922 11 0.367
tube formation GO:0035148 140 0.365
myeloid cell differentiation GO:0030099 233 0.363
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.361
Human
neural tube formation GO:0001841 108 0.361
positive regulation of cardiac muscle cell differentiation GO:2000727 6 0.359
regulation of organelle organization GO:0033043 289 0.358
Mouse
positive regulation of nucleotide metabolic process GO:0045981 114 0.357
Human
sensory perception GO:0007600 245 0.352
Mouse
regulation of epithelial to mesenchymal transition GO:0010717 22 0.345
Mouse
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.341
regulation of protein serine threonine kinase activity GO:0071900 157 0.338
regulation of gliogenesis GO:0014013 50 0.333
neuron death GO:0070997 154 0.329
Mouse
detection of temperature stimulus involved in sensory perception GO:0050961 6 0.326
Mouse
amine metabolic process GO:0009308 45 0.325
detection of external stimulus GO:0009581 61 0.323
Mouse
mammary gland epithelium development GO:0061180 65 0.323
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.322
osteoclast differentiation GO:0030316 62 0.320
Mouse
regulation of chemotaxis GO:0050920 53 0.317
nitrogen compound transport GO:0071705 271 0.316
Mouse
neuroblast proliferation GO:0007405 49 0.312
cardiac muscle cell differentiation GO:0055007 69 0.312
jnk cascade GO:0007254 72 0.311
gliogenesis GO:0042063 141 0.310
primary neural tube formation GO:0014020 95 0.309
regulation of jnk cascade GO:0046328 62 0.307
cranial nerve structural organization GO:0021604 13 0.306
negative regulation of epithelial to mesenchymal transition GO:0010719 6 0.306
lung morphogenesis GO:0060425 50 0.305
kidney development GO:0001822 213 0.305
neuron migration GO:0001764 122 0.304
nerve development GO:0021675 67 0.303
Mouse
cellular homeostasis GO:0019725 240 0.300
Mouse
sensory organ morphogenesis GO:0090596 242 0.300
Mouse
cellular response to carbohydrate stimulus GO:0071322 50 0.299
Mouse
carbohydrate homeostasis GO:0033500 128 0.298
Mouse
regulation of jun kinase activity GO:0043506 40 0.297
positive regulation of stress fiber assembly GO:0051496 9 0.295
Mouse
regulation of hormone levels GO:0010817 211 0.293
Mouse
epidermis development GO:0008544 187 0.290
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.287
Mouse
cranial nerve morphogenesis GO:0021602 26 0.282
Mouse
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.281
positive regulation of hydrolase activity GO:0051345 148 0.276
Human
anatomical structure maturation GO:0071695 49 0.275
positive regulation of protein modification process GO:0031401 299 0.274
positive regulation of jun kinase activity GO:0043507 30 0.274
palate development GO:0060021 76 0.273
Mouse
sympathetic neuron projection guidance GO:0097491 4 0.268
cdc42 protein signal transduction GO:0032488 0 0.268
regulation of transferase activity GO:0051338 263 0.268
immune effector process GO:0002252 321 0.267
Fly
negative regulation of cell growth GO:0030308 44 0.262
notochord morphogenesis GO:0048570 10 0.261
Mouse
forebrain neuron differentiation GO:0021879 52 0.261
regulation of neuron apoptotic process GO:0043523 122 0.257
Mouse
t cell activation GO:0042110 289 0.257
epithelial cell development GO:0002064 159 0.255
Mouse
apoptotic signaling pathway GO:0097190 306 0.253
leukocyte differentiation GO:0002521 342 0.252
Mouse
ovulation GO:0030728 15 0.252
Worm
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.251
Mouse
regulation of neuron projection regeneration GO:0070570 7 0.249
regulation of epithelial cell proliferation GO:0050678 141 0.246
neural tube closure GO:0001843 90 0.245
mesenchymal cell development GO:0014031 93 0.244
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.242
striated muscle tissue development GO:0014706 293 0.234
parasympathetic nervous system development GO:0048486 19 0.234
regulation of homeostatic process GO:0032844 182 0.233
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.232
Mouse
bone development GO:0060348 120 0.230
amide transport GO:0042886 138 0.230
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 65 0.229
Mouse
stress activated mapk cascade GO:0051403 80 0.229
positive regulation of cell death GO:0010942 224 0.228
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.228
Mouse
stem cell proliferation GO:0072089 117 0.226
response to monosaccharide GO:0034284 67 0.225
Mouse
single organism cell adhesion GO:0098602 156 0.224
Mouse
regulation of multi organism process GO:0043900 111 0.224
Worm
regulation of stem cell differentiation GO:2000736 50 0.223
Mouse
wnt signaling pathway GO:0016055 188 0.222
axon regeneration GO:0031103 12 0.222
pigment metabolic process GO:0042440 32 0.222
Fly
glucose homeostasis GO:0042593 128 0.221
Mouse
positive regulation of actin filament bundle assembly GO:0032233 11 0.221
Mouse
peptide secretion GO:0002790 114 0.221
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.219
regulation of secretion by cell GO:1903530 249 0.219
Mouse
cation transport GO:0006812 399 0.217
organelle localization GO:0051640 179 0.216
semaphorin plexin signaling pathway GO:0071526 21 0.216
tissue remodeling GO:0048771 102 0.216
Mouse
positive regulation of nucleoside metabolic process GO:0045979 91 0.215
Human
regulation of stress activated mapk cascade GO:0032872 69 0.213
positive regulation of cellular amine metabolic process GO:0033240 5 0.213
epithelial to mesenchymal transition GO:0001837 47 0.211
Mouse
sympathetic neuron projection extension GO:0097490 4 0.210
skeletal muscle organ development GO:0060538 163 0.210
astrocyte differentiation GO:0048708 43 0.210
regulation of anatomical structure size GO:0090066 178 0.205
peptidyl amino acid modification GO:0018193 336 0.204
positive regulation of neuron projection development GO:0010976 79 0.203
extrinsic apoptotic signaling pathway GO:0097191 126 0.202
stress activated protein kinase signaling cascade GO:0031098 81 0.200
salivary gland development GO:0007431 37 0.199
cellular glucose homeostasis GO:0001678 52 0.198
Mouse
regulation of secretion GO:0051046 274 0.198
Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.197
dichotomous subdivision of an epithelial terminal unit GO:0060600 11 0.197
regulation of cellular response to stress GO:0080135 159 0.197
ion transmembrane transport GO:0034220 361 0.196
regulation of endopeptidase activity GO:0052548 89 0.195
Mouse
glossopharyngeal nerve morphogenesis GO:0021615 4 0.195
regulation of glial cell differentiation GO:0045685 41 0.191
autonomic nervous system development GO:0048483 43 0.191
regulation of cell size GO:0008361 72 0.190
positive regulation of cell projection organization GO:0031346 95 0.189
mammary gland epithelial cell proliferation GO:0033598 24 0.188
Mouse
somite development GO:0061053 81 0.184
positive regulation of stress activated mapk cascade GO:0032874 48 0.182
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.181
facial nerve morphogenesis GO:0021610 11 0.180
inorganic ion transmembrane transport GO:0098660 234 0.179
rhombomere formation GO:0021594 1 0.179
cell chemotaxis GO:0060326 81 0.177
Mouse
establishment or maintenance of cell polarity GO:0007163 86 0.175
Mouse
vagus nerve development GO:0021564 3 0.175
asymmetric neuroblast division GO:0055059 1 0.174
divalent inorganic cation homeostasis GO:0072507 138 0.172
Mouse
mesenchyme development GO:0060485 152 0.171
Mouse
negative regulation of multi organism process GO:0043901 68 0.171
Worm
synapse assembly GO:0007416 56 0.170
Mouse
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.168
positive regulation of synapse assembly GO:0051965 18 0.166
Mouse
oocyte maturation GO:0001556 18 0.165
Worm
microtubule cytoskeleton organization GO:0000226 157 0.164
tube closure GO:0060606 91 0.162
endocardial cushion to mesenchymal transition GO:0090500 5 0.160
regulation of muscle tissue development GO:1901861 97 0.159
bone remodeling GO:0046849 53 0.159
Mouse
learning GO:0007612 98 0.158
Mouse
forebrain generation of neurons GO:0021872 63 0.158
peptide hormone secretion GO:0030072 109 0.158
Mouse
keratinocyte proliferation GO:0043616 21 0.158
sprouting angiogenesis GO:0002040 26 0.158
negative regulation of behavior GO:0048521 14 0.157
notochord cell differentiation GO:0060034 1 0.156
Mouse
rhombomere morphogenesis GO:0021593 2 0.155
smooth muscle cell migration GO:0014909 10 0.154
skin development GO:0043588 220 0.154
morphogenesis of embryonic epithelium GO:0016331 159 0.151
Worm
cardiac muscle tissue development GO:0048738 130 0.151
lung development GO:0030324 164 0.149
transmission of nerve impulse GO:0019226 76 0.146
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.146
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.144
Fly
germ cell development GO:0007281 185 0.144
Worm
vagus nerve morphogenesis GO:0021644 2 0.144
actin filament organization GO:0007015 113 0.143
Mouse
cellular response to glucose stimulus GO:0071333 45 0.143
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.140
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.140
epithelial cell proliferation GO:0050673 174 0.140
Mouse
positive regulation of neuron death GO:1901216 28 0.139
Mouse
positive regulation of cardiac muscle tissue development GO:0055025 19 0.138
regulation of peptide transport GO:0090087 91 0.137
Mouse
negative regulation of reproductive process GO:2000242 31 0.137
Worm
regulation of neuron death GO:1901214 134 0.136
Mouse
transmembrane transport GO:0055085 412 0.136
regulation of organ morphogenesis GO:2000027 144 0.135
muscular septum morphogenesis GO:0003150 4 0.134
cerebellum development GO:0021549 77 0.134
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.133
Mouse
regulation of cell cycle GO:0051726 281 0.132
limb bud formation GO:0060174 10 0.132
cerebral cortex cell migration GO:0021795 44 0.132
protein localization to membrane GO:0072657 108 0.132
positive regulation of kinase activity GO:0033674 155 0.130
hair follicle development GO:0001942 85 0.129
mammary gland morphogenesis GO:0060443 54 0.128
Mouse
regulation of cardiac muscle cell differentiation GO:2000725 9 0.127
regulation of kinase activity GO:0043549 249 0.127
regulation of lipid metabolic process GO:0019216 118 0.126
Mouse
somitogenesis GO:0001756 69 0.126
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.126
regulation of peptidase activity GO:0052547 96 0.125
Mouse
activation of mapk activity GO:0000187 59 0.124
cation homeostasis GO:0055080 212 0.123
Mouse
positive regulation of programmed cell death GO:0043068 218 0.122
Mouse
multicellular organismal signaling GO:0035637 91 0.122
regulation of wnt signaling pathway GO:0030111 123 0.121
learning or memory GO:0007611 148 0.121
Mouse
myelination in peripheral nervous system GO:0022011 19 0.120
regulation of striated muscle cell differentiation GO:0051153 81 0.120
embryonic appendage morphogenesis GO:0035113 126 0.120
regulation of neuron migration GO:2001222 22 0.119
regulation of cell growth GO:0001558 91 0.119
myelination GO:0042552 74 0.119
muscle tissue development GO:0060537 308 0.119
regulation of canonical wnt signaling pathway GO:0060828 82 0.118
ventral trunk neural crest cell migration GO:0036486 4 0.117
negative regulation of cell motility GO:2000146 61 0.116
oocyte differentiation GO:0009994 35 0.116
Worm
preganglionic parasympathetic nervous system development GO:0021783 17 0.116
limb development GO:0060173 166 0.115
embryonic body morphogenesis GO:0010172 10 0.115
Worm
metal ion homeostasis GO:0055065 189 0.114
Mouse
trigeminal nerve development GO:0021559 10 0.114
positive regulation of lymphocyte proliferation GO:0050671 70 0.114
hormone secretion GO:0046879 128 0.113
Mouse
ureteric bud development GO:0001657 94 0.113
regulation of membrane potential GO:0042391 192 0.113
oogenesis GO:0048477 56 0.112
Worm
segmentation GO:0035282 93 0.112
cellular lipid metabolic process GO:0044255 323 0.111
Mouse
kidney morphogenesis GO:0060993 83 0.111
detection of stimulus involved in sensory perception GO:0050906 44 0.110
Mouse
negative regulation of response to wounding GO:1903035 77 0.110
male genitalia morphogenesis GO:0048808 4 0.109
regulation of apoptotic signaling pathway GO:2001233 197 0.109
g protein coupled receptor signaling pathway GO:0007186 243 0.109

Epha4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.222
nervous system disease DOID:863 0 0.222
sensory system disease DOID:0050155 0 0.152
neuropathy DOID:870 0 0.111