Mus musculus

156 known processes

Trim24

tripartite motif-containing 24

(Aliases: AI447469,D430004I05Rik,Tif1a,A130082H20Rik,TIF1alpha,TIF1)

Trim24 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone h3 k9 dimethylation GO:0036123 4 0.999
regulation of histone h3 k9 methylation GO:0051570 8 0.884
dna hypermethylation GO:0044026 3 0.842
regulation of dna methylation GO:0044030 12 0.839
heterochromatin assembly GO:0031507 2 0.832
histone h4 k20 trimethylation GO:0034773 2 0.809
macromolecule methylation GO:0043414 120 0.796
Mouse
heterochromatin organization GO:0070828 4 0.776
positive regulation of histone h3 k9 methylation GO:0051574 4 0.764
histone lysine methylation GO:0034968 50 0.749
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.698
regulation of histone methylation GO:0031060 30 0.689
protein alkylation GO:0008213 81 0.688
histone h3 k9 methylation GO:0051567 17 0.682
regulation of cellular ketone metabolic process GO:0010565 66 0.652
dna alkylation GO:0006305 43 0.646
Mouse
histone methylation GO:0016571 71 0.639
regulation of transcription by chromatin organization GO:0034401 0 0.631
cellular amino acid metabolic process GO:0006520 103 0.611
dna modification GO:0006304 50 0.605
Mouse
covalent chromatin modification GO:0016569 163 0.588
regulation of chromosome organization GO:0033044 83 0.576
amine metabolic process GO:0009308 45 0.569
dna methylation GO:0006306 43 0.542
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.533
olfactory learning GO:0008355 2 0.502
peptidyl lysine trimethylation GO:0018023 12 0.482
cellular ketone metabolic process GO:0042180 84 0.477
positive regulation of cellular amine metabolic process GO:0033240 5 0.475
chromatin organization GO:0006325 206 0.458
Fly
histone h4 k20 methylation GO:0034770 8 0.447
regulation of cellular amine metabolic process GO:0033238 20 0.444
peptidyl lysine methylation GO:0018022 29 0.441
histone modification GO:0016570 159 0.440
positive regulation of histone methylation GO:0031062 16 0.431
positive regulation of chromatin modification GO:1903310 28 0.427
regulation of chromatin modification GO:1903308 57 0.419
cellular amine metabolic process GO:0044106 44 0.414
methylation GO:0032259 134 0.401
Mouse
positive regulation of chromosome organization GO:2001252 33 0.384
regulation of histone modification GO:0031056 56 0.339
protein methylation GO:0006479 81 0.323
telomere maintenance GO:0000723 19 0.305
regulation of chromatin silencing GO:0031935 2 0.269
positive regulation of histone modification GO:0031058 28 0.263
dna packaging GO:0006323 30 0.255
ras protein signal transduction GO:0007265 77 0.249
chromatin modification GO:0016568 187 0.235
peptidyl amino acid modification GO:0018193 336 0.224
peptidyl lysine modification GO:0018205 77 0.221
dna metabolic process GO:0006259 303 0.217
Mouse
regulation of chromatin organization GO:1902275 57 0.213
small gtpase mediated signal transduction GO:0007264 97 0.210
anatomical structure homeostasis GO:0060249 145 0.207
regulation of organelle organization GO:0033043 289 0.189
positive regulation of protein modification process GO:0031401 299 0.173
positive regulation of organelle organization GO:0010638 128 0.160
positive regulation of cellular component biogenesis GO:0044089 94 0.159
chromatin assembly GO:0031497 13 0.148
negative regulation of intracellular signal transduction GO:1902532 167 0.136
dna conformation change GO:0071103 37 0.136
chromatin assembly or disassembly GO:0006333 16 0.127
regulation of cellular component biogenesis GO:0044087 181 0.111
regulation of ras protein signal transduction GO:0046578 114 0.109
multicellular organism growth GO:0035264 161 0.108
chromatin silencing GO:0006342 15 0.106
negative regulation of chromosome organization GO:2001251 30 0.105
negative regulation of organelle organization GO:0010639 90 0.104
gene silencing GO:0016458 38 0.102
dna dealkylation GO:0035510 11 0.081
Mouse
negative regulation of ras protein signal transduction GO:0046580 18 0.077
macromolecule catabolic process GO:0009057 281 0.076
negative regulation of cellular component organization GO:0051129 194 0.076
cognition GO:0050890 149 0.076
positive regulation of growth GO:0045927 104 0.075
intracellular receptor signaling pathway GO:0030522 74 0.073
development of primary sexual characteristics GO:0045137 143 0.067
negative regulation of gene expression epigenetic GO:0045814 15 0.057
negative regulation of cellular protein metabolic process GO:0032269 247 0.054
negative regulation of chromatin modification GO:1903309 19 0.054
protein modification by small protein conjugation GO:0032446 187 0.053
response to vitamin d GO:0033280 3 0.053
peptidyl lysine dimethylation GO:0018027 6 0.053
cellular response to dna damage stimulus GO:0006974 207 0.051
developmental growth involved in morphogenesis GO:0060560 138 0.050
Mouse
cellular response to lipid GO:0071396 145 0.050
cellular protein catabolic process GO:0044257 155 0.049
neuronal action potential GO:0019228 54 0.048
mitotic cell cycle GO:0000278 195 0.046
learning or memory GO:0007611 148 0.044
response to radiation GO:0009314 165 0.043
multicellular organismal signaling GO:0035637 91 0.040
regulation of protein localization GO:0032880 231 0.040
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.039
chromatin remodeling GO:0006338 32 0.039
regulation of membrane potential GO:0042391 192 0.039
protein localization to nucleus GO:0034504 121 0.038
gonad development GO:0008406 141 0.038
associative learning GO:0008306 61 0.037
demethylation GO:0070988 23 0.037
Mouse
negative regulation of cell proliferation GO:0008285 296 0.037
protein catabolic process GO:0030163 221 0.036
microtubule cytoskeleton organization GO:0000226 157 0.034
organelle fission GO:0048285 170 0.034
translation GO:0006412 93 0.034
embryonic placenta development GO:0001892 98 0.033
Mouse
regulation of establishment of protein localization GO:0070201 181 0.032
homeostasis of number of cells GO:0048872 210 0.031
action potential GO:0001508 78 0.031
intracellular protein transport GO:0006886 204 0.031
cytoplasmic transport GO:0016482 234 0.031
protein import GO:0017038 101 0.031
metal ion homeostasis GO:0055065 189 0.031
transmission of nerve impulse GO:0019226 76 0.030
protein autophosphorylation GO:0046777 61 0.030
divalent inorganic cation homeostasis GO:0072507 138 0.030
regulation of cytoplasmic transport GO:1903649 112 0.029
regulation of cytokine production GO:0001817 266 0.029
positive regulation of programmed cell death GO:0043068 218 0.028
stem cell development GO:0048864 219 0.028
Mouse
cell type specific apoptotic process GO:0097285 268 0.028
protein modification by small protein conjugation or removal GO:0070647 207 0.027
axonogenesis GO:0007409 274 0.027
Fly
muscle cell differentiation GO:0042692 261 0.027
striated muscle tissue development GO:0014706 293 0.027
negative regulation of immune system process GO:0002683 209 0.026
gland development GO:0048732 330 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
sensory organ morphogenesis GO:0090596 242 0.026
germ cell development GO:0007281 185 0.025
camera type eye development GO:0043010 266 0.025
response to extracellular stimulus GO:0009991 127 0.025
ubiquitin dependent protein catabolic process GO:0006511 129 0.025
changes to dna methylation involved in embryo development GO:1901538 6 0.025
Mouse
positive regulation of apoptotic process GO:0043065 217 0.025
aromatic compound catabolic process GO:0019439 286 0.024
response to light stimulus GO:0009416 135 0.024
nuclear import GO:0051170 95 0.024
protein targeting GO:0006605 143 0.024
maintenance of location GO:0051235 89 0.024
regulation of intracellular transport GO:0032386 159 0.023
microtubule based process GO:0007017 236 0.023
regulation of cellular response to stress GO:0080135 159 0.023
spermatogenesis GO:0007283 284 0.023
ensheathment of neurons GO:0007272 76 0.023
dna repair GO:0006281 107 0.023
protein import into nucleus GO:0006606 95 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.023
cellular chemical homeostasis GO:0055082 215 0.023
cytokine production GO:0001816 319 0.022
positive regulation of cell death GO:0010942 224 0.022
regulation of protein transport GO:0051223 163 0.022
meiotic cell cycle GO:0051321 122 0.022
protein processing GO:0016485 163 0.022
myeloid cell homeostasis GO:0002262 114 0.022
nitrogen compound transport GO:0071705 271 0.022
cellular response to external stimulus GO:0071496 88 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
sensory perception GO:0007600 245 0.022
regulation of neuron differentiation GO:0045664 281 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
mesenchyme development GO:0060485 152 0.022
Mouse
calcium ion homeostasis GO:0055074 127 0.021
cation homeostasis GO:0055080 212 0.021
interspecies interaction between organisms GO:0044419 83 0.021
regulation of response to alcohol GO:1901419 2 0.021
myelination GO:0042552 74 0.021
regulation of hormone levels GO:0010817 211 0.020
signal transduction by p53 class mediator GO:0072331 51 0.020
cell adhesion GO:0007155 329 0.020
axon ensheathment GO:0008366 76 0.020
forebrain development GO:0030900 302 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
female gamete generation GO:0007292 74 0.020
negative regulation of protein modification process GO:0031400 163 0.020
response to organonitrogen compound GO:0010243 246 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
regulation of secretion by cell GO:1903530 249 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.019
transmembrane transport GO:0055085 412 0.019
cation transport GO:0006812 399 0.019
cellular response to organic cyclic compound GO:0071407 87 0.019
regulation of mitotic cell cycle phase transition GO:1901990 73 0.019
dna demethylation GO:0080111 10 0.019
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.019
genetic imprinting GO:0071514 27 0.019
Mouse
purine nucleoside catabolic process GO:0006152 205 0.019
protein maturation GO:0051604 176 0.019
dna recombination GO:0006310 92 0.019
regulation of hydrolase activity GO:0051336 246 0.018
mitotic cell cycle process GO:1903047 159 0.018
ion transmembrane transport GO:0034220 361 0.018
cation transmembrane transport GO:0098655 266 0.018
developmental maturation GO:0021700 193 0.018
protein ubiquitination GO:0016567 171 0.018
stem cell differentiation GO:0048863 268 0.018
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
regulation of secretion GO:0051046 274 0.018
compound eye development GO:0048749 1 0.018
protein localization to organelle GO:0033365 185 0.018
glucose homeostasis GO:0042593 128 0.018
innate immune response GO:0045087 157 0.018
placenta development GO:0001890 140 0.017
Mouse
regulation of multi organism process GO:0043900 111 0.017
ossification GO:0001503 216 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
regulation of protein targeting GO:1903533 61 0.017
regulation of system process GO:0044057 200 0.017
regulation of homeostatic process GO:0032844 182 0.017
regulation of binding GO:0051098 111 0.017
regulation of response to dna damage stimulus GO:2001020 34 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
immune effector process GO:0002252 321 0.016
neuron projection guidance GO:0097485 141 0.016
Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
cellular homeostasis GO:0019725 240 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
positive regulation of cholesterol homeostasis GO:2000189 2 0.016
tube closure GO:0060606 91 0.016
modification dependent protein catabolic process GO:0019941 133 0.016
negative regulation of mitotic cell cycle GO:0045930 58 0.016
muscle tissue development GO:0060537 308 0.016
regulation of cell activation GO:0050865 289 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
skeletal muscle organ development GO:0060538 163 0.016
appendage development GO:0048736 166 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
myeloid cell differentiation GO:0030099 233 0.016
dendrite development GO:0016358 115 0.016
Fly
regulation of proteolysis GO:0030162 164 0.016
protein oligomerization GO:0051259 67 0.016
rho protein signal transduction GO:0007266 32 0.016
nuclear transport GO:0051169 139 0.015
lipid localization GO:0010876 126 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
appendage morphogenesis GO:0035107 149 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
t cell activation GO:0042110 289 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
vitamin d receptor signaling pathway GO:0070561 2 0.015
skeletal system development GO:0001501 356 0.015
circulatory system process GO:0003013 197 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
urogenital system development GO:0001655 261 0.015
cellular lipid metabolic process GO:0044255 323 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
male gamete generation GO:0048232 285 0.015
meiotic nuclear division GO:0007126 115 0.015
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
nucleoside metabolic process GO:0009116 246 0.014
organic acid biosynthetic process GO:0016053 86 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
limb morphogenesis GO:0035108 149 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
regulation of protein maturation GO:1903317 96 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
divalent metal ion transport GO:0070838 172 0.014
regulation of protein processing GO:0070613 96 0.014
neuron death GO:0070997 154 0.014
proteasomal protein catabolic process GO:0010498 98 0.014
spermatid differentiation GO:0048515 115 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
purine containing compound metabolic process GO:0072521 311 0.013
mitotic nuclear division GO:0007067 48 0.013
membrane organization GO:0061024 245 0.013
amide transport GO:0042886 138 0.013
nucleotide catabolic process GO:0009166 217 0.013
leukocyte differentiation GO:0002521 342 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
cellular response to acid chemical GO:0071229 68 0.013
photoreceptor cell differentiation GO:0046530 52 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
response to uv GO:0009411 44 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
response to acid chemical GO:0001101 111 0.013
cellular ion homeostasis GO:0006873 165 0.013
limb development GO:0060173 166 0.013
digestive tract development GO:0048565 190 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
regulation of mapk cascade GO:0043408 248 0.013
negative regulation of molecular function GO:0044092 258 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
post embryonic retina morphogenesis in camera type eye GO:0060060 3 0.012
regulation of antimicrobial humoral response GO:0002759 3 0.012
translational initiation GO:0006413 24 0.012
ear development GO:0043583 200 0.012
embryonic appendage morphogenesis GO:0035113 126 0.012
kidney development GO:0001822 213 0.012
response to vitamin a GO:0033189 1 0.012
wnt signaling pathway GO:0016055 188 0.012
cellular response to nutrient levels GO:0031669 64 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
regulation of protein complex assembly GO:0043254 83 0.012
meiotic cell cycle process GO:1903046 77 0.012
negative regulation of cytokine production GO:0001818 84 0.012
response to organic cyclic compound GO:0014070 198 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
regulation of cell projection organization GO:0031344 206 0.012
negative regulation of dna replication GO:0008156 4 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
organic anion transport GO:0015711 137 0.012
oxidation reduction process GO:0055114 342 0.012
multi multicellular organism process GO:0044706 109 0.012
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
peptide transport GO:0015833 133 0.012
regulation of protein localization to nucleus GO:1900180 60 0.012
respiratory tube development GO:0030323 167 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
carbohydrate metabolic process GO:0005975 230 0.012
learning GO:0007612 98 0.012
modulation by virus of host morphology or physiology GO:0019048 3 0.012
chemotaxis GO:0006935 247 0.011
Fly
negative regulation of multi organism process GO:0043901 68 0.011
regulation of protein kinase activity GO:0045859 232 0.011
skin development GO:0043588 220 0.011
organophosphate catabolic process GO:0046434 232 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
negative regulation of cell cycle process GO:0010948 69 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
positive regulation of translational initiation GO:0045948 4 0.011
regulation of protein binding GO:0043393 60 0.011
divalent inorganic cation transport GO:0072511 178 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
positive regulation of nervous system development GO:0051962 221 0.011
eye photoreceptor cell differentiation GO:0001754 41 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
inflammatory response GO:0006954 244 0.011
fat soluble vitamin biosynthetic process GO:0042362 4 0.011
regulation of defense response GO:0031347 233 0.011
lateral inhibition GO:0046331 1 0.011
regulation of translational initiation GO:0006446 15 0.011
neural tube formation GO:0001841 108 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
mapk cascade GO:0000165 281 0.011
organelle localization GO:0051640 179 0.011
response to nutrient levels GO:0031667 109 0.011
circadian rhythm GO:0007623 114 0.011
cellular response to gamma radiation GO:0071480 4 0.011
apoptotic signaling pathway GO:0097190 306 0.011
chemosensory behavior GO:0007635 11 0.011
response to inorganic substance GO:0010035 96 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
lipid biosynthetic process GO:0008610 179 0.011
regulation of anatomical structure size GO:0090066 178 0.011
regulation of translation GO:0006417 71 0.011
digestive system development GO:0055123 200 0.011
regulation of kinase activity GO:0043549 249 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
actin cytoskeleton organization GO:0030036 220 0.011
chromosome segregation GO:0007059 48 0.011
heart morphogenesis GO:0003007 178 0.011
positive regulation of defense response GO:0031349 124 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
endomembrane system organization GO:0010256 147 0.011
cellular response to vitamin GO:0071295 2 0.011
response to peptide hormone GO:0043434 127 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.010
neural tube development GO:0021915 160 0.010
sensory perception of mechanical stimulus GO:0050954 107 0.010
ribonucleotide metabolic process GO:0009259 291 0.010
midgut development GO:0007494 4 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
meiosis i GO:0007127 60 0.010
peptide secretion GO:0002790 114 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
photoreceptor cell development GO:0042461 40 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
positive regulation of transferase activity GO:0051347 167 0.010
regulation of response to wounding GO:1903034 189 0.010
embryonic limb morphogenesis GO:0030326 126 0.010
cellularization GO:0007349 1 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
Human
cellular protein complex assembly GO:0043623 116 0.010
positive regulation of cytokine production GO:0001819 174 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.010
hormone secretion GO:0046879 128 0.010
leukocyte mediated immunity GO:0002443 174 0.010
oocyte axis specification GO:0007309 2 0.010
gastrulation GO:0007369 116 0.010
regulation of innate immune response GO:0045088 91 0.010
antimicrobial peptide biosynthetic process GO:0002777 2 0.010

Trim24 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.028
Human
disease of cellular proliferation DOID:14566 0 0.028
Human
organ system cancer DOID:0050686 0 0.025
Human
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.015
immune system disease DOID:2914 0 0.012
musculoskeletal system disease DOID:17 0 0.011
hematopoietic system disease DOID:74 0 0.011
eye disease DOID:5614 0 0.011