Mus musculus

30 known processes

Itpka

inositol 1,4,5-trisphosphate 3-kinase A

(Aliases: MGC28924)

Itpka biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.184
Mouse
membrane organization GO:0061024 245 0.114
cellular amino acid metabolic process GO:0006520 103 0.109
small gtpase mediated signal transduction GO:0007264 97 0.100
Mouse
regulation of organelle organization GO:0033043 289 0.086
synaptic transmission GO:0007268 329 0.086
immune effector process GO:0002252 321 0.081
regulation of cellular amino acid metabolic process GO:0006521 5 0.080
cellular lipid metabolic process GO:0044255 323 0.080
positive regulation of cellular amine metabolic process GO:0033240 5 0.074
regulation of cellular amine metabolic process GO:0033238 20 0.074
regulation of cellular catabolic process GO:0031329 242 0.072
amine metabolic process GO:0009308 45 0.070
regulation of protein kinase activity GO:0045859 232 0.070
regulation of ras protein signal transduction GO:0046578 114 0.069
Mouse
regulation of mapk cascade GO:0043408 248 0.067
regulation of cell projection organization GO:0031344 206 0.067
purine ribonucleoside catabolic process GO:0046130 205 0.064
cation transport GO:0006812 399 0.064
aromatic compound catabolic process GO:0019439 286 0.063
regulation of cellular ketone metabolic process GO:0010565 66 0.063
muscle tissue development GO:0060537 308 0.063
cellular ketone metabolic process GO:0042180 84 0.063
heterocycle catabolic process GO:0046700 280 0.061
ion transmembrane transport GO:0034220 361 0.060
mapk cascade GO:0000165 281 0.060
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.058
positive regulation of mapk cascade GO:0043410 170 0.057
transmembrane transport GO:0055085 412 0.057
cellular amine metabolic process GO:0044106 44 0.057
wound healing GO:0042060 157 0.057
purine nucleoside triphosphate catabolic process GO:0009146 203 0.055
negative regulation of protein metabolic process GO:0051248 282 0.055
purine nucleotide metabolic process GO:0006163 302 0.055
purine nucleoside metabolic process GO:0042278 241 0.054
cellular macromolecule catabolic process GO:0044265 206 0.054
positive regulation of nervous system development GO:0051962 221 0.053
microtubule based process GO:0007017 236 0.053
cellular homeostasis GO:0019725 240 0.053
cellular nitrogen compound catabolic process GO:0044270 280 0.053
ribonucleoside metabolic process GO:0009119 245 0.052
organophosphate catabolic process GO:0046434 232 0.052
protein localization to membrane GO:0072657 108 0.051
nucleoside metabolic process GO:0009116 246 0.051
exocytosis GO:0006887 121 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
glycosyl compound catabolic process GO:1901658 206 0.050
nucleotide metabolic process GO:0009117 332 0.050
peptidyl amino acid modification GO:0018193 336 0.049
organic cyclic compound catabolic process GO:1901361 295 0.049
macromolecule catabolic process GO:0009057 281 0.049
purine containing compound metabolic process GO:0072521 311 0.049
cytoplasmic transport GO:0016482 234 0.048
regulation of neuron differentiation GO:0045664 281 0.048
establishment of vesicle localization GO:0051650 81 0.048
purine nucleoside catabolic process GO:0006152 205 0.046
regulation of kinase activity GO:0043549 249 0.046
nucleoside triphosphate metabolic process GO:0009141 230 0.045
positive regulation of programmed cell death GO:0043068 218 0.045
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.044
endomembrane system organization GO:0010256 147 0.044
cytokine production GO:0001816 319 0.043
purine nucleotide catabolic process GO:0006195 211 0.043
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.043
nucleoside triphosphate catabolic process GO:0009143 205 0.043
regulation of cellular component size GO:0032535 121 0.043
rho protein signal transduction GO:0007266 32 0.042
nucleoside catabolic process GO:0009164 206 0.042
negative regulation of cellular protein metabolic process GO:0032269 247 0.042
nucleobase containing small molecule metabolic process GO:0055086 352 0.042
purine ribonucleotide metabolic process GO:0009150 290 0.042
positive regulation of cell death GO:0010942 224 0.042
regulation of synaptic plasticity GO:0048167 87 0.041
nitrogen compound transport GO:0071705 271 0.040
ribonucleoside triphosphate metabolic process GO:0009199 220 0.040
purine nucleoside triphosphate metabolic process GO:0009144 226 0.039
purine containing compound catabolic process GO:0072523 213 0.039
protein catabolic process GO:0030163 221 0.039
developmental maturation GO:0021700 193 0.039
ribonucleotide catabolic process GO:0009261 208 0.038
regulation of membrane potential GO:0042391 192 0.038
ribonucleoside catabolic process GO:0042454 206 0.038
transmission of nerve impulse GO:0019226 76 0.037
peptidyl tyrosine modification GO:0018212 145 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.036
purine ribonucleoside metabolic process GO:0046128 241 0.036
cation transmembrane transport GO:0098655 266 0.036
purine ribonucleotide catabolic process GO:0009154 208 0.036
ribonucleotide metabolic process GO:0009259 291 0.036
negative regulation of phosphorus metabolic process GO:0010563 184 0.035
gtp catabolic process GO:0006184 143 0.035
striated muscle tissue development GO:0014706 293 0.035
cation homeostasis GO:0055080 212 0.034
leukocyte differentiation GO:0002521 342 0.034
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.034
positive regulation of protein modification process GO:0031401 299 0.034
regulation of purine nucleotide metabolic process GO:1900542 169 0.034
organonitrogen compound biosynthetic process GO:1901566 192 0.034
negative regulation of molecular function GO:0044092 258 0.034
establishment of organelle localization GO:0051656 122 0.034
positive regulation of cellular catabolic process GO:0031331 148 0.034
ribonucleoside triphosphate catabolic process GO:0009203 199 0.034
regulation of hydrolase activity GO:0051336 246 0.034
cellular protein catabolic process GO:0044257 155 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.033
positive regulation of cell development GO:0010720 237 0.033
positive regulation of apoptotic process GO:0043065 217 0.033
muscle cell differentiation GO:0042692 261 0.033
regulation of hormone levels GO:0010817 211 0.032
regulation of nucleotide metabolic process GO:0006140 169 0.032
peptidyl tyrosine phosphorylation GO:0018108 143 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.032
carbohydrate derivative biosynthetic process GO:1901137 183 0.032
positive regulation of protein phosphorylation GO:0001934 242 0.032
regulation of transferase activity GO:0051338 263 0.032
ribose phosphate metabolic process GO:0019693 291 0.031
negative regulation of cellular component organization GO:0051129 194 0.031
protein modification by small protein conjugation GO:0032446 187 0.031
embryonic organ morphogenesis GO:0048562 276 0.031
regulation of map kinase activity GO:0043405 120 0.030
organelle localization GO:0051640 179 0.030
organonitrogen compound catabolic process GO:1901565 264 0.030
modification dependent macromolecule catabolic process GO:0043632 133 0.030
regulation of ion transport GO:0043269 215 0.030
microtubule cytoskeleton organization GO:0000226 157 0.030
meiotic cell cycle GO:0051321 122 0.030
positive regulation of transferase activity GO:0051347 167 0.029
guanosine containing compound catabolic process GO:1901069 144 0.029
regulation of secretion GO:0051046 274 0.029
multicellular organismal signaling GO:0035637 91 0.029
nucleotide catabolic process GO:0009166 217 0.029
actin cytoskeleton organization GO:0030036 220 0.029
lymphocyte mediated immunity GO:0002449 139 0.029
protein maturation GO:0051604 176 0.029
regulation of protein serine threonine kinase activity GO:0071900 157 0.028
activation of immune response GO:0002253 138 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.028
response to organonitrogen compound GO:0010243 246 0.028
inorganic cation transmembrane transport GO:0098662 207 0.028
regulation of cellular component biogenesis GO:0044087 181 0.028
spermatogenesis GO:0007283 284 0.028
axonogenesis GO:0007409 274 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
reactive oxygen species biosynthetic process GO:1903409 8 0.028
neuron projection extension GO:1990138 64 0.027
intracellular protein transport GO:0006886 204 0.027
regulation of cytokine production GO:0001817 266 0.027
single organism cell adhesion GO:0098602 156 0.027
regulation of cell adhesion GO:0030155 154 0.027
muscle system process GO:0003012 141 0.027
regulation of purine nucleotide catabolic process GO:0033121 122 0.027
regulation of lymphocyte activation GO:0051249 240 0.027
Mouse
plasma membrane organization GO:0007009 90 0.027
regulation of cell cycle process GO:0010564 160 0.027
positive regulation of hydrolase activity GO:0051345 148 0.027
regulation of homeostatic process GO:0032844 182 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.026
alcohol metabolic process GO:0006066 116 0.026
g protein coupled receptor signaling pathway GO:0007186 243 0.026
cellular response to growth factor stimulus GO:0071363 197 0.026
positive regulation of gtpase activity GO:0043547 85 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
reactive nitrogen species metabolic process GO:2001057 0 0.026
cellular response to organonitrogen compound GO:0071417 145 0.026
leukocyte mediated immunity GO:0002443 174 0.026
regulation of secretion by cell GO:1903530 249 0.026
protein ubiquitination GO:0016567 171 0.025
cellular chemical homeostasis GO:0055082 215 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.025
regulation of protein localization GO:0032880 231 0.025
calcium ion transport GO:0006816 159 0.025
negative regulation of phosphorylation GO:0042326 166 0.025
regulation of cellular response to stress GO:0080135 159 0.025
regionalization GO:0003002 337 0.025
dephosphorylation GO:0016311 129 0.025
modification dependent protein catabolic process GO:0019941 133 0.025
male gamete generation GO:0048232 285 0.025
positive regulation of ras gtpase activity GO:0032320 65 0.025
response to molecule of bacterial origin GO:0002237 143 0.025
camera type eye development GO:0043010 266 0.025
peptide transport GO:0015833 133 0.025
ubiquitin dependent protein catabolic process GO:0006511 129 0.025
protein processing GO:0016485 163 0.025
neuronal action potential GO:0019228 54 0.024
rap protein signal transduction GO:0032486 3 0.024
regulation of neuron projection development GO:0010975 169 0.024
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.024
response to growth factor GO:0070848 198 0.024
positive regulation of protein kinase activity GO:0045860 144 0.024
regulation of gtp catabolic process GO:0033124 113 0.024
protein targeting GO:0006605 143 0.024
stress activated protein kinase signaling cascade GO:0031098 81 0.024
hormone secretion GO:0046879 128 0.023
protein localization to organelle GO:0033365 185 0.023
regulation of anatomical structure size GO:0090066 178 0.023
cellular protein complex assembly GO:0043623 116 0.023
germ cell development GO:0007281 185 0.023
cell activation involved in immune response GO:0002263 126 0.023
positive regulation of nucleotide catabolic process GO:0030813 88 0.023
regulation of proteolysis GO:0030162 164 0.023
positive regulation of nucleoside metabolic process GO:0045979 91 0.023
phospholipid metabolic process GO:0006644 87 0.023
negative regulation of protein modification process GO:0031400 163 0.023
inorganic ion transmembrane transport GO:0098660 234 0.023
oocyte axis specification GO:0007309 2 0.023
regulation of cytoskeleton organization GO:0051493 122 0.023
organic hydroxy compound biosynthetic process GO:1901617 77 0.023
positive regulation of neuron differentiation GO:0045666 141 0.023
positive regulation of gtp catabolic process GO:0033126 85 0.023
ameboidal type cell migration GO:0001667 128 0.022
multi multicellular organism process GO:0044706 109 0.022
organelle fission GO:0048285 170 0.022
cell recognition GO:0008037 83 0.022
negative regulation of neuron differentiation GO:0045665 101 0.022
regulation of cell migration GO:0030334 219 0.022
single organismal cell cell adhesion GO:0016337 131 0.022
locomotory behavior GO:0007626 195 0.022
negative regulation of nervous system development GO:0051961 156 0.022
gtp metabolic process GO:0046039 144 0.022
establishment of protein localization to membrane GO:0090150 54 0.022
respiratory tube development GO:0030323 167 0.022
regulation of cell substrate adhesion GO:0010810 73 0.022
regulation of cell cycle GO:0051726 281 0.022
proteasomal protein catabolic process GO:0010498 98 0.021
tube formation GO:0035148 140 0.021
regulation of lipid metabolic process GO:0019216 118 0.021
regulation of nucleoside metabolic process GO:0009118 130 0.021
oocyte construction GO:0007308 2 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.021
regulation of nucleotide catabolic process GO:0030811 122 0.021
mitotic cell cycle GO:0000278 195 0.021
actin filament organization GO:0007015 113 0.021
response to extracellular stimulus GO:0009991 127 0.021
response to organic cyclic compound GO:0014070 198 0.021
stem cell differentiation GO:0048863 268 0.021
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
midgut development GO:0007494 4 0.021
positive regulation of kinase activity GO:0033674 155 0.021
regulation of protein maturation GO:1903317 96 0.021
nuclear division GO:0000280 158 0.021
apoptotic signaling pathway GO:0097190 306 0.021
carbohydrate homeostasis GO:0033500 128 0.021
regulation of intracellular transport GO:0032386 159 0.021
mitochondrion organization GO:0007005 134 0.021
divalent inorganic cation transport GO:0072511 178 0.020
skeletal system development GO:0001501 356 0.020
developmental growth involved in morphogenesis GO:0060560 138 0.020
divalent metal ion transport GO:0070838 172 0.020
innate immune response GO:0045087 157 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
negative regulation of immune system process GO:0002683 209 0.020
angiogenesis GO:0001525 201 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
neural tube development GO:0021915 160 0.020
positive regulation of secretion by cell GO:1903532 114 0.020
jnk cascade GO:0007254 72 0.020
action potential GO:0001508 78 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
divalent inorganic cation homeostasis GO:0072507 138 0.020
monocarboxylic acid metabolic process GO:0032787 191 0.020
t cell activation GO:0042110 289 0.020
Mouse
glycerolipid metabolic process GO:0046486 122 0.019
cell division GO:0051301 120 0.019
cellular metal ion homeostasis GO:0006875 151 0.019
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
digestive system development GO:0055123 200 0.019
cell junction maintenance GO:0034331 4 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
antimicrobial peptide biosynthetic process GO:0002777 2 0.019
regulation of leukocyte differentiation GO:1902105 159 0.019
Mouse
intracellular mrna localization GO:0008298 4 0.019
regulation of t cell activation GO:0050863 170 0.019
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.019
establishment or maintenance of cell polarity GO:0007163 86 0.019
cellular ion homeostasis GO:0006873 165 0.019
immune response regulating signaling pathway GO:0002764 125 0.019
positive regulation of cell projection organization GO:0031346 95 0.019
gland development GO:0048732 330 0.019
vesicle localization GO:0051648 86 0.019
glycoprotein metabolic process GO:0009100 116 0.018
positive regulation of map kinase activity GO:0043406 84 0.018
regulation of protein processing GO:0070613 96 0.018
calcium ion homeostasis GO:0055074 127 0.018
inflammatory response GO:0006954 244 0.018
protein secretion GO:0009306 111 0.018
cell growth GO:0016049 130 0.018
regulation of cell activation GO:0050865 289 0.018
Mouse
protein localization to nucleus GO:0034504 121 0.018
digestive tract morphogenesis GO:0048546 147 0.018
lung development GO:0030324 164 0.018
positive regulation of secretion GO:0051047 130 0.018
regulation of long term synaptic depression GO:1900452 3 0.018
response to nutrient levels GO:0031667 109 0.018
maintenance of location GO:0051235 89 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
metal ion homeostasis GO:0055065 189 0.018
pole plasm assembly GO:0007315 2 0.018
glucose homeostasis GO:0042593 128 0.018
anion transport GO:0006820 177 0.017
inclusion body assembly GO:0070841 3 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
dna metabolic process GO:0006259 303 0.017
adaptive immune response GO:0002250 155 0.017
response to lipopolysaccharide GO:0032496 128 0.017
immune response activating signal transduction GO:0002757 116 0.017
neuron neuron synaptic transmission GO:0007270 69 0.017
regulation of cell size GO:0008361 72 0.017
regulation of jnk cascade GO:0046328 62 0.017
leukocyte activation involved in immune response GO:0002366 126 0.017
digestive tract development GO:0048565 190 0.017
lymphocyte differentiation GO:0030098 242 0.017
Mouse
cell type specific apoptotic process GO:0097285 268 0.017
compound eye development GO:0048749 1 0.017
positive regulation of cellular component biogenesis GO:0044089 94 0.017
positive regulation of nucleotide metabolic process GO:0045981 114 0.017
negative regulation of synapse assembly GO:0051964 3 0.017
positive regulation of defense response GO:0031349 124 0.017
establishment of tissue polarity GO:0007164 28 0.017
leukocyte proliferation GO:0070661 172 0.017
myeloid cell differentiation GO:0030099 233 0.017
respiratory system development GO:0060541 190 0.017
small molecule biosynthetic process GO:0044283 132 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
cell substrate adhesion GO:0031589 130 0.016
regulation of protein complex assembly GO:0043254 83 0.016
positive regulation of cytokine production GO:0001819 174 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
blood circulation GO:0008015 195 0.016
response to transforming growth factor beta GO:0071559 88 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
regulation of protein catabolic process GO:0042176 108 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
muscle cell development GO:0055001 133 0.016
sequestering of metal ion GO:0051238 19 0.016
regulation of system process GO:0044057 200 0.016
regulation of response to wounding GO:1903034 189 0.016
positive regulation of immune effector process GO:0002699 107 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.016
regulation of transmembrane transport GO:0034762 128 0.016
potassium ion transport GO:0006813 52 0.016
regulation of body fluid levels GO:0050878 162 0.016
vesicle organization GO:0016050 60 0.016
chromatin organization GO:0006325 206 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
cell maturation GO:0048469 127 0.016
placenta development GO:0001890 140 0.016
positive regulation of organelle organization GO:0010638 128 0.016
meiotic nuclear division GO:0007126 115 0.016
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.016
regulation of cell motility GO:2000145 236 0.016
gastrulation GO:0007369 116 0.016
negative regulation of protein maturation GO:1903318 79 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.016
homeostasis of number of cells GO:0048872 210 0.015
insulin secretion GO:0030073 89 0.015
regulation of defense response GO:0031347 233 0.015
cofactor metabolic process GO:0051186 80 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
amide transport GO:0042886 138 0.015
epithelial cell proliferation GO:0050673 174 0.015
gonad development GO:0008406 141 0.015
regulation of actin cytoskeleton organization GO:0032956 84 0.015
lateral inhibition GO:0046331 1 0.015
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.015
b cell activation GO:0042113 161 0.015
morphogenesis of a polarized epithelium GO:0001738 37 0.015
fat cell differentiation GO:0045444 160 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
negative regulation of cell cycle GO:0045786 123 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
telencephalon development GO:0021537 186 0.015
microtubule based movement GO:0007018 84 0.015
negative regulation of hydrolase activity GO:0051346 71 0.015
skeletal system morphogenesis GO:0048705 203 0.015
interleukin 8 production GO:0032637 4 0.015
embryonic placenta development GO:0001892 98 0.015
developmental cell growth GO:0048588 84 0.015
regulation of exocytosis GO:0017157 61 0.015
glucose transport GO:0015758 56 0.015
positive regulation of leukocyte differentiation GO:1902107 86 0.015
Mouse
cognition GO:0050890 149 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
response to oxidative stress GO:0006979 123 0.015
myotube differentiation GO:0014902 105 0.015
production of molecular mediator of immune response GO:0002440 103 0.015
antimicrobial peptide production GO:0002775 2 0.015
cell adhesion GO:0007155 329 0.015
establishment of protein localization to organelle GO:0072594 118 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.014
regulation of leukocyte mediated immunity GO:0002703 104 0.014
epithelial tube formation GO:0072175 130 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
regulation of ras gtpase activity GO:0032318 88 0.014
response to radiation GO:0009314 165 0.014
heart process GO:0003015 94 0.014
stem cell development GO:0048864 219 0.014
negative regulation of cell development GO:0010721 169 0.014
mitotic cell cycle process GO:1903047 159 0.014
sensory perception GO:0007600 245 0.014
neuron death GO:0070997 154 0.014
regulation of extent of cell growth GO:0061387 52 0.014
apoptotic mitochondrial changes GO:0008637 48 0.014
stress activated mapk cascade GO:0051403 80 0.014
protein localization to plasma membrane GO:0072659 57 0.014
mitotic cytokinesis GO:0000281 4 0.014
synaptic vesicle localization GO:0097479 59 0.014
peptidyl serine phosphorylation GO:0018105 74 0.014
cellular amide metabolic process GO:0043603 58 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
sequestering of calcium ion GO:0051208 18 0.014
skeletal muscle organ development GO:0060538 163 0.014
response to inorganic substance GO:0010035 96 0.014
neuromuscular process controlling balance GO:0050885 59 0.014
regulation of chloride transport GO:2001225 2 0.014
wnt signaling pathway GO:0016055 188 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
response to acid chemical GO:0001101 111 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.014
glucose import GO:0046323 32 0.014
response to epidermal growth factor GO:0070849 4 0.014
negative regulation of transferase activity GO:0051348 85 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
maternal determination of anterior posterior axis embryo GO:0008358 2 0.014
synapse organization GO:0050808 125 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
neuromuscular process GO:0050905 99 0.013
neural tube formation GO:0001841 108 0.013
oocyte anterior posterior axis specification GO:0007314 2 0.013
cellular response to extracellular stimulus GO:0031668 81 0.013
negative regulation of cell projection organization GO:0031345 56 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
positive regulation of jnk cascade GO:0046330 46 0.013
organic anion transport GO:0015711 137 0.013
regulation of alpha beta t cell activation GO:0046634 53 0.013
Mouse
lymphocyte proliferation GO:0046651 164 0.013
lymphocyte activation involved in immune response GO:0002285 93 0.013
establishment of synaptic vesicle localization GO:0097480 57 0.013
t cell proliferation GO:0042098 120 0.013
negative regulation of neuron projection development GO:0010977 50 0.013
regulation of protein transport GO:0051223 163 0.013
activation of meiosis GO:0090427 4 0.013
carboxylic acid transport GO:0046942 100 0.013
blood vessel morphogenesis GO:0048514 285 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
Mouse
heart morphogenesis GO:0003007 178 0.013
striated muscle cell development GO:0055002 125 0.013
negative regulation of protein processing GO:0010955 79 0.013
positive regulation of cell adhesion GO:0045785 80 0.013
rna interference GO:0016246 2 0.013
regulation of cell division GO:0051302 76 0.013
epithelial cell migration GO:0010631 63 0.013
sulfur compound metabolic process GO:0006790 100 0.013
heart contraction GO:0060047 93 0.013
muscle fiber development GO:0048747 76 0.013
regulation of ovulation GO:0060278 3 0.013
positive regulation of cell cycle GO:0045787 92 0.013
epidermis development GO:0008544 187 0.013
neuron apoptotic process GO:0051402 142 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.013
cardiac muscle tissue development GO:0048738 130 0.013
dendrite development GO:0016358 115 0.013
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.013
monosaccharide transport GO:0015749 58 0.013
localization within membrane GO:0051668 4 0.013
protein oligomerization GO:0051259 67 0.013
testosterone biosynthetic process GO:0061370 2 0.013
fertilization GO:0009566 127 0.013
cerebellar cortex development GO:0021695 48 0.013
oxidation reduction process GO:0055114 342 0.013
regulation of cellular protein catabolic process GO:1903362 61 0.013
response to parathyroid hormone GO:0071107 3 0.013
cytokine biosynthetic process GO:0042089 68 0.013
negative regulation of kinase activity GO:0033673 81 0.013
circulatory system process GO:0003013 197 0.013
regulation of cysteine type endopeptidase activity GO:2000116 65 0.012
positive regulation of ion transport GO:0043270 65 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
positive regulation of cell activation GO:0050867 158 0.012
Mouse
organelle assembly GO:0070925 177 0.012
habituation GO:0046959 3 0.012
protein polymerization GO:0051258 57 0.012
segmentation GO:0035282 93 0.012
establishment of planar polarity GO:0001736 28 0.012
organic acid biosynthetic process GO:0016053 86 0.012
urogenital system development GO:0001655 261 0.012
cell junction organization GO:0034330 77 0.012

Itpka disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
central nervous system disease DOID:331 0 0.013