Mus musculus

0 known processes

Them4

thioesterase superfamily member 4

(Aliases: 2700077M13Rik,4921507I02Rik)

Them4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.051
cellular ketone metabolic process GO:0042180 84 0.047
regulation of cellular amine metabolic process GO:0033238 20 0.046
amine metabolic process GO:0009308 45 0.045
oxidation reduction process GO:0055114 342 0.042
cellular lipid metabolic process GO:0044255 323 0.042
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
cellular amine metabolic process GO:0044106 44 0.039
regulation of cellular ketone metabolic process GO:0010565 66 0.035
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.033
monocarboxylic acid metabolic process GO:0032787 191 0.031
aromatic compound catabolic process GO:0019439 286 0.031
male gamete generation GO:0048232 285 0.031
nucleotide metabolic process GO:0009117 332 0.031
transmembrane transport GO:0055085 412 0.030
organic cyclic compound catabolic process GO:1901361 295 0.030
regulation of cellular catabolic process GO:0031329 242 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.030
lipid biosynthetic process GO:0008610 179 0.028
small gtpase mediated signal transduction GO:0007264 97 0.028
anion transport GO:0006820 177 0.028
heterocycle catabolic process GO:0046700 280 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
ras protein signal transduction GO:0007265 77 0.027
spermatogenesis GO:0007283 284 0.027
regulation of organelle organization GO:0033043 289 0.027
purine containing compound metabolic process GO:0072521 311 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
regulation of hydrolase activity GO:0051336 246 0.026
negative regulation of protein metabolic process GO:0051248 282 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
ribonucleoside metabolic process GO:0009119 245 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
ion transmembrane transport GO:0034220 361 0.024
rho protein signal transduction GO:0007266 32 0.024
cellular homeostasis GO:0019725 240 0.024
sensory perception GO:0007600 245 0.023
peptidyl amino acid modification GO:0018193 336 0.023
membrane organization GO:0061024 245 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
nucleoside metabolic process GO:0009116 246 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
fatty acid metabolic process GO:0006631 121 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
cytoplasmic transport GO:0016482 234 0.021
macromolecule catabolic process GO:0009057 281 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
small molecule biosynthetic process GO:0044283 132 0.021
cation transport GO:0006812 399 0.021
organophosphate catabolic process GO:0046434 232 0.021
dna metabolic process GO:0006259 303 0.021
nucleotide catabolic process GO:0009166 217 0.020
nitrogen compound transport GO:0071705 271 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.020
cellular alcohol biosynthetic process GO:0044108 3 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
leukocyte differentiation GO:0002521 342 0.019
intracellular protein transport GO:0006886 204 0.019
regulation of hormone levels GO:0010817 211 0.019
response to organic cyclic compound GO:0014070 198 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
apoptotic signaling pathway GO:0097190 306 0.019
response to organonitrogen compound GO:0010243 246 0.019
carbohydrate metabolic process GO:0005975 230 0.019
mapk cascade GO:0000165 281 0.019
renal system development GO:0072001 225 0.019
protein localization to organelle GO:0033365 185 0.019
nucleoside catabolic process GO:0009164 206 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.018
cation homeostasis GO:0055080 212 0.018
cellular response to dna damage stimulus GO:0006974 207 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
organic anion transport GO:0015711 137 0.018
germ cell development GO:0007281 185 0.018
positive regulation of protein modification process GO:0031401 299 0.018
camera type eye development GO:0043010 266 0.018
spermatid differentiation GO:0048515 115 0.018
protein maturation GO:0051604 176 0.018
cellular chemical homeostasis GO:0055082 215 0.018
endomembrane system organization GO:0010256 147 0.018
regulation of protein localization GO:0032880 231 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
cation transmembrane transport GO:0098655 266 0.018
cell type specific apoptotic process GO:0097285 268 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
negative regulation of cell proliferation GO:0008285 296 0.017
regulation of protein kinase activity GO:0045859 232 0.017
striated muscle tissue development GO:0014706 293 0.017
synaptic transmission GO:0007268 329 0.017
organelle fission GO:0048285 170 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
muscle tissue development GO:0060537 308 0.017
fat cell differentiation GO:0045444 160 0.017
calcitriol biosynthetic process from calciol GO:0036378 3 0.017
positive regulation of cell development GO:0010720 237 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
purine containing compound catabolic process GO:0072523 213 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
protein ubiquitination GO:0016567 171 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
protein catabolic process GO:0030163 221 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
immune effector process GO:0002252 321 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
protein processing GO:0016485 163 0.016
regulation of cell activation GO:0050865 289 0.016
cytokine production GO:0001816 319 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
microtubule based process GO:0007017 236 0.016
regulation of proteolysis GO:0030162 164 0.016
cell adhesion GO:0007155 329 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
regulation of anatomical structure size GO:0090066 178 0.016
fat soluble vitamin biosynthetic process GO:0042362 4 0.016
protein localization to membrane GO:0072657 108 0.016
spermatid development GO:0007286 108 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
myeloid cell differentiation GO:0030099 233 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
vitamin d3 metabolic process GO:0070640 3 0.016
regulation of intracellular transport GO:0032386 159 0.015
sequestering of calcium ion GO:0051208 18 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
regulation of ion transport GO:0043269 215 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
metal ion homeostasis GO:0055065 189 0.015
cellular protein catabolic process GO:0044257 155 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
negative regulation of molecular function GO:0044092 258 0.015
urogenital system development GO:0001655 261 0.015
carboxylic acid transport GO:0046942 100 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
muscle cell differentiation GO:0042692 261 0.015
regulation of neuron differentiation GO:0045664 281 0.015
protein targeting GO:0006605 143 0.015
cellular ion homeostasis GO:0006873 165 0.015
actin cytoskeleton organization GO:0030036 220 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
t cell activation GO:0042110 289 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
mitochondrion organization GO:0007005 134 0.014
sensory organ morphogenesis GO:0090596 242 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
regulation of cell projection organization GO:0031344 206 0.014
inflammatory response GO:0006954 244 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
methylation GO:0032259 134 0.014
response to radiation GO:0009314 165 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
steroid metabolic process GO:0008202 119 0.014
ossification GO:0001503 216 0.014
cellular alcohol metabolic process GO:0044107 3 0.014
organelle localization GO:0051640 179 0.014
homeostasis of number of cells GO:0048872 210 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
dephosphorylation GO:0016311 129 0.014
locomotory behavior GO:0007626 195 0.014
negative regulation of protein modification process GO:0031400 163 0.014
innate immune response GO:0045087 157 0.014
response to acid chemical GO:0001101 111 0.014
thermosensory behavior GO:0040040 1 0.014
lipid transport GO:0006869 98 0.014
blood circulation GO:0008015 195 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
skin development GO:0043588 220 0.014
organelle assembly GO:0070925 177 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.013
gland development GO:0048732 330 0.013
kidney development GO:0001822 213 0.013
vitamin d biosynthetic process GO:0042368 3 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
regulation of cell motility GO:2000145 236 0.013
organic acid transport GO:0015849 101 0.013
developmental maturation GO:0021700 193 0.013
regulation of transferase activity GO:0051338 263 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
maintenance of location GO:0051235 89 0.013
skeletal system development GO:0001501 356 0.013
cellular response to lipid GO:0071396 145 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
chemotaxis GO:0006935 247 0.013
cellular protein complex assembly GO:0043623 116 0.013
cofactor transport GO:0051181 4 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
cofactor metabolic process GO:0051186 80 0.013
axonogenesis GO:0007409 274 0.013
positive regulation of cell death GO:0010942 224 0.013
regulation of secretion by cell GO:1903530 249 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
organic acid biosynthetic process GO:0016053 86 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
positive regulation of nervous system development GO:0051962 221 0.013
lymphocyte differentiation GO:0030098 242 0.013
chromatin organization GO:0006325 206 0.013
regulation of secretion GO:0051046 274 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
multicellular organismal signaling GO:0035637 91 0.013
response to growth factor GO:0070848 198 0.013
regulation of cellular component size GO:0032535 121 0.012
response to inorganic substance GO:0010035 96 0.012
negative regulation of immune system process GO:0002683 209 0.012
nuclear division GO:0000280 158 0.012
regulation of membrane potential GO:0042391 192 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
regulation of cytokine production GO:0001817 266 0.012
respiratory system development GO:0060541 190 0.012
cell growth GO:0016049 130 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
regulation of mapk cascade GO:0043408 248 0.012
regulation of protein catabolic process GO:0042176 108 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
plasma membrane organization GO:0007009 90 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
regulation of homeostatic process GO:0032844 182 0.012
regulation of kinase activity GO:0043549 249 0.012
nuclear transport GO:0051169 139 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
secondary alcohol metabolic process GO:1902652 3 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
divalent inorganic cation transport GO:0072511 178 0.012
circulatory system process GO:0003013 197 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
regulation of t cell activation GO:0050863 170 0.012
epidermis development GO:0008544 187 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
anatomical structure homeostasis GO:0060249 145 0.012
regulation of defense response GO:0031347 233 0.012
chromosome organization involved in meiosis GO:0070192 39 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
regulation of cell cycle GO:0051726 281 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
forebrain development GO:0030900 302 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
epithelial cell development GO:0002064 159 0.012
response to nutrient levels GO:0031667 109 0.012
glycerolipid metabolic process GO:0046486 122 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
positive regulation of neuron differentiation GO:0045666 141 0.011
response to extracellular stimulus GO:0009991 127 0.011
ear development GO:0043583 200 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
regulation of cell adhesion GO:0030155 154 0.011
lateral inhibition GO:0046331 1 0.011
positive regulation of organelle organization GO:0010638 128 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
sequestering of metal ion GO:0051238 19 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
lipid localization GO:0010876 126 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
meiotic cell cycle GO:0051321 122 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
regulation of cellular response to stress GO:0080135 159 0.011
epithelial cell proliferation GO:0050673 174 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
chromatin modification GO:0016568 187 0.011
rhodopsin mediated signaling pathway GO:0016056 4 0.011
positive regulation of transferase activity GO:0051347 167 0.011
regulation of system process GO:0044057 200 0.011
single organism cell adhesion GO:0098602 156 0.011
regulation of peptidase activity GO:0052547 96 0.011
tissue homeostasis GO:0001894 115 0.011
divalent metal ion transport GO:0070838 172 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
meiotic nuclear division GO:0007126 115 0.011
wnt signaling pathway GO:0016055 188 0.011
oocyte construction GO:0007308 2 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
lymphocyte proliferation GO:0046651 164 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
skeletal muscle organ development GO:0060538 163 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
cell maturation GO:0048469 127 0.010
mitotic cell cycle GO:0000278 195 0.010
transmission of nerve impulse GO:0019226 76 0.010
regulation of cytoskeleton organization GO:0051493 122 0.010
glycoprotein metabolic process GO:0009100 116 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010
organic acid catabolic process GO:0016054 51 0.010
calcium ion homeostasis GO:0055074 127 0.010
macromolecule methylation GO:0043414 120 0.010
myosin filament assembly GO:0031034 2 0.010
small molecule catabolic process GO:0044282 71 0.010
amide transport GO:0042886 138 0.010
neuron apoptotic process GO:0051402 142 0.010
alcohol metabolic process GO:0006066 116 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
response to lipopolysaccharide GO:0032496 128 0.010
dna repair GO:0006281 107 0.010
gtp catabolic process GO:0006184 143 0.010
lung development GO:0030324 164 0.010
neuron death GO:0070997 154 0.010
peptide transport GO:0015833 133 0.010
negative regulation of cell development GO:0010721 169 0.010
carboxylic acid catabolic process GO:0046395 51 0.010
wound healing GO:0042060 157 0.010
regulation of protein transport GO:0051223 163 0.010
regulation of transmembrane transport GO:0034762 128 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
response to peptide hormone GO:0043434 127 0.010
cell substrate adhesion GO:0031589 130 0.010
regulation of binding GO:0051098 111 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010

Them4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
musculoskeletal system disease DOID:17 0 0.018
disease of metabolism DOID:0014667 0 0.017
immune system disease DOID:2914 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
inherited metabolic disorder DOID:655 0 0.015
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014
central nervous system disease DOID:331 0 0.013
connective tissue disease DOID:65 0 0.013
hematopoietic system disease DOID:74 0 0.012
cardiovascular system disease DOID:1287 0 0.012
eye disease DOID:5614 0 0.011
bone disease DOID:0080001 0 0.010