|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.888
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.832
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.822
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.765
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.763
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.745
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.720
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.691
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.690
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.684
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.678
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.675
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.614
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.574
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.566
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.545
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.530
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.517
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.508
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.501
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.487
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.446
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.443
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.438
|
Human |
|
|
placenta development
|
GO:0001890 |
140 |
0.431
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.429
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.429
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.427
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.427
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.426
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.419
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.418
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.405
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.402
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.393
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.393
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.384
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.384
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.371
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.361
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.356
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.354
|
Rat |
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.353
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.345
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.338
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.334
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.334
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.328
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.326
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.325
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.325
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.320
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.316
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.316
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.314
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.312
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.310
|
Human |
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.307
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.301
|
Human |
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.291
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.290
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.289
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.279
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.279
|
|
|
|
branching involved in mammary gland duct morphogenesis
|
GO:0060444 |
27 |
0.277
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.274
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.273
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.270
|
Human Rat |
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.266
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.265
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.265
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.264
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.263
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.262
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.261
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.261
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.257
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.252
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.249
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.246
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.243
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.241
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.240
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.237
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.233
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.232
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.231
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.229
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.228
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.228
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.228
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.227
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.223
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.222
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.221
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.221
|
Human |
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.220
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.219
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.218
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.215
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.215
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.210
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.208
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.207
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.205
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.205
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.203
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.203
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.199
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.198
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.198
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.198
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.197
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.196
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.193
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.190
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.190
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.190
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.190
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.189
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.189
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.188
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.187
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.186
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.184
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.184
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.183
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.182
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.182
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.181
|
|
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
24 |
0.181
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.178
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.178
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.174
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.173
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.173
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.171
|
|
|
|
mammary gland duct morphogenesis
|
GO:0060603 |
38 |
0.171
|
|
|
|
myoblast differentiation
|
GO:0045445 |
52 |
0.168
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.167
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.167
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.162
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.161
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.158
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.158
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.157
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.156
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.156
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.155
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.155
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
39 |
0.155
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.154
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.152
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.152
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.151
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.148
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.148
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.147
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.147
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.146
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.146
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.145
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.145
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.144
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.144
|
|
|
|
positive regulation of smooth muscle cell migration
|
GO:0014911 |
4 |
0.143
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.143
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.142
|
Rat |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.142
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.142
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.140
|
Human |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.140
|
Human |
|
|
response to radiation
|
GO:0009314 |
165 |
0.139
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.138
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.138
|
Human |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.137
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.137
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.135
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.135
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.134
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.133
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.132
|
Rat |
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.131
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.131
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.131
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.130
|
|
|
|
exogenous drug catabolic process
|
GO:0042738 |
1 |
0.130
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.128
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.128
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.127
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.127
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.127
|
Rat |
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.125
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
34 |
0.125
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.124
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.124
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.123
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.123
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.123
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.122
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.121
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.119
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.119
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.119
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.119
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.117
|
Rat |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.117
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.117
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.116
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.115
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.115
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.114
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.114
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.114
|
|
|
|
cellular response to interleukin 18
|
GO:0071351 |
3 |
0.114
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.113
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.111
|
Human |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.111
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.111
|
Human |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.111
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.110
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.109
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.108
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.108
|
Human Rat |
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.107
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.107
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.107
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.106
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.105
|
|
|
|
skeletal muscle tissue regeneration
|
GO:0043403 |
20 |
0.104
|
|
|
|
wnt signaling pathway calcium modulating pathway
|
GO:0007223 |
2 |
0.102
|
|
|
|
maintenance of cell number
|
GO:0098727 |
3 |
0.102
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.102
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.102
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
4 |
0.101
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.101
|
Human |
|
|
female gamete generation
|
GO:0007292 |
74 |
0.101
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.100
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.099
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.099
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.099
|
Human |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.099
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.098
|
Human |
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.098
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.097
|
|
|
|
response to interleukin 18
|
GO:0070673 |
4 |
0.097
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.097
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.096
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.096
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.096
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.095
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.095
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.095
|
Human |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.094
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.094
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.094
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.094
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.093
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.092
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.092
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.092
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.092
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.092
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.092
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.092
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.091
|
|
|
|
dna replication
|
GO:0006260 |
52 |
0.091
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.090
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.089
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.089
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.089
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
25 |
0.089
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.088
|
Human Rat |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.087
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.087
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.087
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.087
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.087
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.086
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.086
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.086
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.085
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.085
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
26 |
0.085
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.085
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.085
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.084
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.084
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.084
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.083
|
|
|
|
drug catabolic process
|
GO:0042737 |
2 |
0.083
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.081
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.081
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.081
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.081
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.080
|
Human |
|
|
syncytium formation
|
GO:0006949 |
43 |
0.080
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.080
|
Human |
|
|
cell aging
|
GO:0007569 |
35 |
0.080
|
|
|
|
olfactory bulb development
|
GO:0021772 |
30 |
0.080
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.079
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.079
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.079
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.079
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.078
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.078
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.078
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.078
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.078
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.078
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.078
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.077
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.076
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.076
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.076
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.076
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.076
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.076
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.076
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.076
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.075
|
Human |
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
20 |
0.075
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.075
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.075
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.075
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.074
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.074
|
|
|
|
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
|
GO:0014834 |
3 |
0.074
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.074
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.073
|
|
|
|
regulation of muscle adaptation
|
GO:0043502 |
31 |
0.073
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.072
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.072
|
Human |
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.072
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.072
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.072
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.071
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.071
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.071
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.071
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.070
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.070
|
|
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.070
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.070
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.070
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.069
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.069
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.069
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
30 |
0.068
|
|
|
|
heart growth
|
GO:0060419 |
45 |
0.068
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.068
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.068
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.068
|
|
|
|
cell growth involved in cardiac muscle cell development
|
GO:0061049 |
3 |
0.068
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.067
|
Human |
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.067
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.067
|
|
|
|
prostate gland development
|
GO:0030850 |
48 |
0.067
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.067
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.067
|
Human |
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
66 |
0.067
|
|
|
|
central nervous system morphogenesis
|
GO:0021551 |
2 |
0.067
|
|
|
|
smad protein complex assembly
|
GO:0007183 |
1 |
0.066
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.066
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.066
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.066
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.066
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.066
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.066
|
Human |
|
|
glucose transport
|
GO:0015758 |
56 |
0.065
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.065
|
Human |
|
|
amide transport
|
GO:0042886 |
138 |
0.065
|
Rat |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.065
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.065
|
|
|
|
diencephalon development
|
GO:0021536 |
63 |
0.065
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.065
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.065
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
46 |
0.065
|
|
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.065
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.064
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.064
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.064
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.064
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.064
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.064
|
Rat |
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.064
|
Human |
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.063
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.063
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.063
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.063
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.063
|
|
|
|
regulation of androgen receptor signaling pathway
|
GO:0060765 |
3 |
0.062
|
|
|
|
embryonic digit morphogenesis
|
GO:0042733 |
56 |
0.062
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.062
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.062
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.061
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.061
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.061
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.061
|
Rat |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.061
|
|
|
|
female gonad development
|
GO:0008585 |
71 |
0.061
|
|
|
|
apoptotic process involved in mammary gland involution
|
GO:0060057 |
4 |
0.060
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.060
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.060
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.060
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.060
|
|
|
|
interleukin 18 mediated signaling pathway
|
GO:0035655 |
2 |
0.059
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.059
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.059
|
|
|
|
inflammatory response to wounding
|
GO:0090594 |
4 |
0.059
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.059
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
25 |
0.059
|
|
|
|
negative regulation of serotonin uptake
|
GO:0051612 |
2 |
0.058
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.058
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.058
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.058
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.058
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.058
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.058
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.058
|
|
|
|
positive regulation of mammary gland involution
|
GO:1903521 |
4 |
0.058
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.058
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.057
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.057
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.057
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.057
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.057
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.056
|
Human |
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
34 |
0.056
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.056
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.056
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.056
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.056
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.055
|
Human |
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.055
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.055
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.055
|
|
|
|
tertiary branching involved in mammary gland duct morphogenesis
|
GO:0060748 |
3 |
0.055
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.054
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.054
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.054
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.054
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.053
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.053
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.053
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.053
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.053
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.052
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.052
|
|
|
|
blastocyst formation
|
GO:0001825 |
33 |
0.052
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.052
|
|
|
|
olfactory lobe development
|
GO:0021988 |
32 |
0.052
|
|
|
|
drug metabolic process
|
GO:0017144 |
4 |
0.052
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.052
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.052
|
Human |
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.051
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.051
|
|
|
|
regulation of transforming growth factor beta2 production
|
GO:0032909 |
2 |
0.051
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
4 |
0.051
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.051
|
Human |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.051
|
|
|
|
cell differentiation involved in embryonic placenta development
|
GO:0060706 |
26 |
0.050
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
22 |
0.050
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.050
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.050
|
|
|
|
regeneration
|
GO:0031099 |
38 |
0.049
|
Rat |
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.049
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.049
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.049
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.049
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.049
|
|
|
|
specification of organ identity
|
GO:0010092 |
30 |
0.049
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.049
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.049
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.049
|
Human |
|
|
regulation of blood vessel size
|
GO:0050880 |
56 |
0.048
|
|
|
|
regulation of chronic inflammatory response to antigenic stimulus
|
GO:0002874 |
3 |
0.048
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
4 |
0.048
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.048
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.048
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.048
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.048
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.048
|
Human |
|
|
nuclear import
|
GO:0051170 |
95 |
0.047
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.047
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.047
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.047
|
|
|
|
serotonin uptake
|
GO:0051610 |
3 |
0.047
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.047
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.047
|
Human |
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.047
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.046
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.046
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.046
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.046
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.046
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.046
|
|
|
|
regulation of organ growth
|
GO:0046620 |
61 |
0.046
|
|
|
|
mammary gland branching involved in pregnancy
|
GO:0060745 |
6 |
0.046
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.045
|
|