Mus musculus

60 known processes

Mat2a

methionine adenosyltransferase II, alpha

(Aliases: D630045P18Rik,MGC6545)

Mat2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.540
rna processing GO:0006396 105 0.410
rna splicing via transesterification reactions GO:0000375 43 0.388
mrna splicing via spliceosome GO:0000398 43 0.384
rna splicing GO:0008380 54 0.357
ribonucleoprotein complex subunit organization GO:0071826 28 0.188
mrna processing GO:0006397 63 0.179
regulation of mrna metabolic process GO:1903311 43 0.161
regulation of mrna splicing via spliceosome GO:0048024 32 0.137
organic cyclic compound catabolic process GO:1901361 295 0.102
regulation of alternative mrna splicing via spliceosome GO:0000381 8 0.092
regulation of mrna processing GO:0050684 41 0.086
regulation of cell cycle GO:0051726 281 0.083
transmembrane transport GO:0055085 412 0.078
rna interference GO:0016246 2 0.075
mrna metabolic process GO:0016071 84 0.072
alternative mrna splicing via spliceosome GO:0000380 12 0.070
apoptotic signaling pathway GO:0097190 306 0.064
posttranscriptional gene silencing by rna GO:0035194 10 0.061
nitrogen compound transport GO:0071705 271 0.060
positive regulation of cell death GO:0010942 224 0.060
spliceosomal complex assembly GO:0000245 6 0.060
posttranscriptional regulation of gene expression GO:0010608 155 0.059
cation transport GO:0006812 399 0.055
macromolecule catabolic process GO:0009057 281 0.053
negative regulation of molecular function GO:0044092 258 0.053
heterocycle catabolic process GO:0046700 280 0.053
amine metabolic process GO:0009308 45 0.052
regulation of rna splicing GO:0043484 37 0.050
regulation of apoptotic signaling pathway GO:2001233 197 0.046
gene silencing GO:0016458 38 0.044
cellular amine metabolic process GO:0044106 44 0.044
mitochondrion organization GO:0007005 134 0.044
regulation of cell division GO:0051302 76 0.043
cellular nitrogen compound catabolic process GO:0044270 280 0.041
ribonucleoprotein complex disassembly GO:0032988 3 0.040
positive regulation of apoptotic process GO:0043065 217 0.039
organelle fission GO:0048285 170 0.038
regulation of androgen receptor signaling pathway GO:0060765 3 0.037
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
regulation of nuclear division GO:0051783 56 0.036
cation transmembrane transport GO:0098655 266 0.036
cellular amino acid metabolic process GO:0006520 103 0.035
gonad development GO:0008406 141 0.034
positive regulation of proteolysis GO:0045862 85 0.034
purine containing compound metabolic process GO:0072521 311 0.034
regulation of cellular response to stress GO:0080135 159 0.034
protein complex disassembly GO:0043241 40 0.033
nucleoside metabolic process GO:0009116 246 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.032
negative regulation of mrna processing GO:0050686 12 0.032
posttranscriptional gene silencing GO:0016441 10 0.032
protein refolding GO:0042026 1 0.031
spermatogenesis GO:0007283 284 0.031
small gtpase mediated signal transduction GO:0007264 97 0.031
aromatic compound catabolic process GO:0019439 286 0.030
positive regulation of programmed cell death GO:0043068 218 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 4 0.029
striated muscle tissue development GO:0014706 293 0.029
cell type specific apoptotic process GO:0097285 268 0.029
regulation of kinase activity GO:0043549 249 0.029
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.029
regulation of muscle tissue development GO:1901861 97 0.027
cytoplasmic transport GO:0016482 234 0.027
inorganic ion transmembrane transport GO:0098660 234 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
ion transmembrane transport GO:0034220 361 0.026
regulation of ion transport GO:0043269 215 0.026
blood circulation GO:0008015 195 0.026
membrane organization GO:0061024 245 0.026
positive regulation of cellular catabolic process GO:0031331 148 0.026
negative regulation of phosphorylation GO:0042326 166 0.026
nucleocytoplasmic transport GO:0006913 139 0.026
muscle tissue development GO:0060537 308 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
oxidation reduction process GO:0055114 342 0.025
negative regulation of phosphate metabolic process GO:0045936 184 0.025
cellular homeostasis GO:0019725 240 0.025
regulation of cellular amine metabolic process GO:0033238 20 0.024
male gamete generation GO:0048232 285 0.024
mitochondrial transport GO:0006839 36 0.024
cellular ketone metabolic process GO:0042180 84 0.024
protein modification by small protein conjugation GO:0032446 187 0.024
wnt signaling pathway GO:0016055 188 0.024
androgen receptor signaling pathway GO:0030521 8 0.024
development of primary sexual characteristics GO:0045137 143 0.024
nuclear division GO:0000280 158 0.023
multicellular organism growth GO:0035264 161 0.023
myosin filament organization GO:0031033 3 0.023
muscle contraction GO:0006936 101 0.023
negative regulation of phosphorus metabolic process GO:0010563 184 0.023
angiogenesis GO:0001525 201 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
regulation of transmembrane transport GO:0034762 128 0.022
regulation of membrane potential GO:0042391 192 0.022
gene silencing by rna GO:0031047 19 0.022
morphogenesis of embryonic epithelium GO:0016331 159 0.022
organic acid biosynthetic process GO:0016053 86 0.022
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.022
receptor biosynthetic process GO:0032800 3 0.022
divalent metal ion transport GO:0070838 172 0.022
regulation of cell activation GO:0050865 289 0.022
camera type eye development GO:0043010 266 0.021
blood vessel morphogenesis GO:0048514 285 0.021
circulatory system process GO:0003013 197 0.021
positive regulation of dna templated transcription elongation GO:0032786 2 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
regulation of transferase activity GO:0051338 263 0.021
carboxylic acid biosynthetic process GO:0046394 86 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
cellular lipid metabolic process GO:0044255 323 0.020
oogenesis GO:0048477 56 0.020
peptidyl amino acid modification GO:0018193 336 0.020
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.020
extrinsic apoptotic signaling pathway GO:0097191 126 0.019
ossification GO:0001503 216 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
nuclear transport GO:0051169 139 0.019
protein targeting GO:0006605 143 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
cellular chemical homeostasis GO:0055082 215 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
regulation of meiotic cell cycle GO:0051445 34 0.019
macromolecular complex disassembly GO:0032984 43 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
carbohydrate homeostasis GO:0033500 128 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
nucleotide catabolic process GO:0009166 217 0.018
divalent inorganic cation transport GO:0072511 178 0.018
establishment of rna localization GO:0051236 18 0.018
germ cell development GO:0007281 185 0.018
regulation of binding GO:0051098 111 0.018
sequestering of metal ion GO:0051238 19 0.018
regulation of organelle organization GO:0033043 289 0.018
negative regulation of protein modification process GO:0031400 163 0.018
skeletal muscle cell differentiation GO:0035914 66 0.018
regulation of hydrolase activity GO:0051336 246 0.017
sensory perception GO:0007600 245 0.017
regulation of metal ion transport GO:0010959 106 0.017
muscle cell differentiation GO:0042692 261 0.017
glucose homeostasis GO:0042593 128 0.017
immune effector process GO:0002252 321 0.017
mitotic nuclear division GO:0007067 48 0.017
regulation of protein complex disassembly GO:0043244 28 0.017
stem cell differentiation GO:0048863 268 0.017
cell division GO:0051301 120 0.017
fertilization GO:0009566 127 0.016
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.016
purine containing compound catabolic process GO:0072523 213 0.016
negative regulation of cell development GO:0010721 169 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
transmission of nerve impulse GO:0019226 76 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
regulation of cell cycle process GO:0010564 160 0.016
b cell activation GO:0042113 161 0.016
calcium ion transport GO:0006816 159 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
actin cytoskeleton organization GO:0030036 220 0.015
multicellular organismal signaling GO:0035637 91 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
regulation of hormone levels GO:0010817 211 0.015
endocytosis GO:0006897 168 0.015
cell adhesion GO:0007155 329 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
regulation of protein kinase activity GO:0045859 232 0.015
signal transduction by p53 class mediator GO:0072331 51 0.015
lipid transport GO:0006869 98 0.015
regulation of cell cycle checkpoint GO:1901976 9 0.015
regulation of response to wounding GO:1903034 189 0.015
negative regulation of mrna splicing via spliceosome GO:0048025 12 0.014
ras protein signal transduction GO:0007265 77 0.014
sperm motility GO:0030317 47 0.014
action potential GO:0001508 78 0.014
regulation of exit from mitosis GO:0007096 1 0.014
inflammatory response GO:0006954 244 0.014
embryonic limb morphogenesis GO:0030326 126 0.014
regulation of cell adhesion GO:0030155 154 0.014
myosin filament assembly GO:0031034 2 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
tissue homeostasis GO:0001894 115 0.014
organophosphate catabolic process GO:0046434 232 0.014
protein catabolic process GO:0030163 221 0.014
nucleobase containing compound transport GO:0015931 27 0.014
protein targeting to mitochondrion GO:0006626 6 0.014
intracellular receptor signaling pathway GO:0030522 74 0.014
regulation of protein localization GO:0032880 231 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
respiratory system development GO:0060541 190 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
regulation of adaptive immune response GO:0002819 90 0.013
rho protein signal transduction GO:0007266 32 0.013
sequestering of calcium ion GO:0051208 18 0.013
regulation of cellular ketone metabolic process GO:0010565 66 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
negative regulation of transferase activity GO:0051348 85 0.013
female gamete generation GO:0007292 74 0.013
regulation of mapk cascade GO:0043408 248 0.013
heart process GO:0003015 94 0.013
mitotic cell cycle GO:0000278 195 0.013
skeletal system development GO:0001501 356 0.013
meiotic nuclear division GO:0007126 115 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
cognition GO:0050890 149 0.013
nucleic acid transport GO:0050657 18 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
response to oxidative stress GO:0006979 123 0.013
regulation of cell motility GO:2000145 236 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
regulation of ossification GO:0030278 112 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
negative regulation of adaptive immune response GO:0002820 25 0.012
anatomical structure homeostasis GO:0060249 145 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 1 0.012
adaptive immune response GO:0002250 155 0.012
ribosome biogenesis GO:0042254 20 0.012
mapk cascade GO:0000165 281 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
negative regulation of binding GO:0051100 39 0.012
actomyosin structure organization GO:0031032 56 0.012
positive regulation of growth GO:0045927 104 0.012
stem cell development GO:0048864 219 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
regulation of proteolysis GO:0030162 164 0.012
trna wobble base modification GO:0002097 2 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.012
intracellular protein transport GO:0006886 204 0.012
circadian regulation of gene expression GO:0032922 48 0.012
calcium ion transmembrane transport GO:0070588 85 0.012
negative regulation of rna splicing GO:0033119 12 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
single fertilization GO:0007338 82 0.012
muscle system process GO:0003012 141 0.012
protein localization to nucleus GO:0034504 121 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
mrna splice site selection GO:0006376 5 0.011
regionalization GO:0003002 337 0.011
heart contraction GO:0060047 93 0.011
cell activation involved in immune response GO:0002263 126 0.011
spermatid differentiation GO:0048515 115 0.011
striated muscle cell development GO:0055002 125 0.011
dna metabolic process GO:0006259 303 0.011
neuronal action potential GO:0019228 54 0.011
ear development GO:0043583 200 0.011
striated muscle contraction GO:0006941 45 0.011
cellular response to oxidative stress GO:0034599 76 0.011
protein localization to organelle GO:0033365 185 0.011
response to extracellular stimulus GO:0009991 127 0.011
pharynx development GO:0060465 1 0.011
epidermis development GO:0008544 187 0.011
negative regulation of kinase activity GO:0033673 81 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
epithelial cell proliferation GO:0050673 174 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
rna catabolic process GO:0006401 29 0.010
striated muscle myosin thick filament assembly GO:0071688 1 0.010
circadian rhythm GO:0007623 114 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010
regulation of transcription by chromatin organization GO:0034401 0 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
ribonucleotide catabolic process GO:0009261 208 0.010
monocarboxylic acid biosynthetic process GO:0072330 61 0.010
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.010
lung development GO:0030324 164 0.010
regulation of plasma lipoprotein particle levels GO:0097006 23 0.010
cellular potassium ion transport GO:0071804 43 0.010
translation GO:0006412 93 0.010
adult locomotory behavior GO:0008344 91 0.010
negative regulation of protein metabolic process GO:0051248 282 0.010
regulation of epithelial cell proliferation GO:0050678 141 0.010
skin development GO:0043588 220 0.010
gland development GO:0048732 330 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
cellular ion homeostasis GO:0006873 165 0.010
cytokine production GO:0001816 319 0.010
regulation of dna damage checkpoint GO:2000001 3 0.010
response to organonitrogen compound GO:0010243 246 0.010
adult behavior GO:0030534 135 0.010

Mat2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.036
muscular disease DOID:0080000 0 0.036
disease of anatomical entity DOID:7 0 0.036
musculoskeletal system disease DOID:17 0 0.036
muscle tissue disease DOID:66 0 0.036
nervous system disease DOID:863 0 0.010