|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.960
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.905
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.884
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.880
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.817
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.743
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.741
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.735
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.726
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.708
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.693
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.663
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.639
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.587
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.581
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.580
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.575
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.574
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.572
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.567
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.564
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.543
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.522
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.506
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.463
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.433
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.422
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.396
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.388
|
|
|
|
gamma delta t cell lineage commitment
|
GO:0002365 |
1 |
0.384
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.382
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.376
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.374
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.371
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.370
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.364
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.361
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.357
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.357
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.341
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.338
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.337
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.336
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.330
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.324
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.322
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.311
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.310
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.306
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.294
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.291
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.288
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.286
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.281
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.274
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.267
|
|
|
|
regulation of lymphocyte anergy
|
GO:0002911 |
4 |
0.264
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.260
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.255
|
|
|
|
regulation of interleukin 2 biosynthetic process
|
GO:0045076 |
13 |
0.241
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.237
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.235
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.234
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.227
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.226
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.225
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.220
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.213
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.211
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.205
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.203
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.196
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.195
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.195
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.190
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.189
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.187
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
15 |
0.186
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.181
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.181
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.179
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.179
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.177
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.177
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.174
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.172
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.170
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.164
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.163
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.163
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.163
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.162
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.162
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.161
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.161
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.161
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.161
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.157
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.156
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.150
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.150
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.149
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.146
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.145
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.143
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.141
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.139
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.138
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.137
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.135
|
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.132
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.132
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.128
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.128
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.128
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.128
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.127
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.126
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.124
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.124
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.123
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.122
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.122
|
Mouse |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.119
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.119
|
|
|
|
positive regulation of lymphocyte anergy
|
GO:0002913 |
4 |
0.119
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.119
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.118
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.116
|
|
|
|
t cell anergy
|
GO:0002870 |
4 |
0.116
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.114
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.113
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.112
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.111
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.111
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.111
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.110
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.110
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.108
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.107
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.107
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.106
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.106
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.106
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.105
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.103
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.101
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.101
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.101
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.100
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.098
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.098
|
|
|
|
lymphocyte anergy
|
GO:0002249 |
4 |
0.097
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.097
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.096
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.095
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.095
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.094
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.094
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.092
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.091
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.090
|
|
|
|
positive regulation of interleukin 4 production
|
GO:0032753 |
15 |
0.090
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.089
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.088
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.088
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.087
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.086
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.086
|
|
|
|
regulation of interleukin 4 biosynthetic process
|
GO:0045402 |
3 |
0.086
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.085
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.085
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.084
|
Mouse |
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
6 |
0.083
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.082
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.082
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.079
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.077
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.076
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.076
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.075
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.075
|
|
|
|
regulation of asymmetric cell division
|
GO:0009786 |
4 |
0.075
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.075
|
|
|
|
positive regulation of interleukin 2 biosynthetic process
|
GO:0045086 |
8 |
0.074
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.074
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.074
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.074
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.074
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.073
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.073
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.073
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.073
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.072
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.072
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.072
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.072
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.071
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.071
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.070
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.070
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.070
|
|
|
|
cofactor transport
|
GO:0051181 |
4 |
0.070
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.069
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.069
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
2 |
0.069
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.068
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.068
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.068
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.067
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.066
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.066
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.066
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.066
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.066
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.066
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.065
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.065
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.065
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.064
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.063
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.063
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.063
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.062
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.062
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.062
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.061
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.061
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.061
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.061
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.060
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.060
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.060
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.060
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.059
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.058
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.057
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.057
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.057
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.057
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.057
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.057
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
28 |
0.056
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.056
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.056
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.056
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.056
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.055
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.055
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.055
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.055
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.055
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.054
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.054
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.054
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.054
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.053
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.053
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.053
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.053
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.053
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.053
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.052
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.052
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.052
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.052
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.051
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.051
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.051
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.050
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.050
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
30 |
0.050
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.049
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.049
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.049
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.049
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.049
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.049
|
|
|
|
interleukin 2 secretion
|
GO:0070970 |
7 |
0.048
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.048
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.048
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.048
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.047
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.047
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.047
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.047
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.047
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.047
|
|
|
|
detection of molecule of bacterial origin
|
GO:0032490 |
2 |
0.046
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.046
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.046
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.046
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.046
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.046
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.046
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.046
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.045
|
|
|
|
regulation of interleukin 4 production
|
GO:0032673 |
18 |
0.045
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.045
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.045
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.045
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.045
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.045
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.044
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.044
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
44 |
0.044
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.044
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.043
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.043
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.043
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
12 |
0.043
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.043
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.043
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.043
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.042
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.042
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.042
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.042
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.042
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.042
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.042
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
18 |
0.042
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.042
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.042
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
53 |
0.042
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.041
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.041
|
|
|
|
positive regulation of immune complex clearance by monocytes and macrophages
|
GO:0090265 |
2 |
0.041
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.041
|
Mouse |
|
|
actin filament organization
|
GO:0007015 |
113 |
0.041
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.040
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.040
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.040
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
16 |
0.040
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.040
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.040
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.039
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.038
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.038
|
|
|
|
regulation of mesenchymal cell proliferation involved in ureter development
|
GO:0072199 |
3 |
0.038
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.038
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.038
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.038
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.038
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.038
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.038
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.037
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.037
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.037
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.037
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.037
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.037
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
56 |
0.037
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.037
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.037
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.036
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.036
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.036
|
|
|
|
negative regulation of interleukin 2 biosynthetic process
|
GO:0045085 |
3 |
0.036
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.036
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.036
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.036
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.036
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.036
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.036
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.036
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.035
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.035
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.035
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.035
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.035
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.035
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.034
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.034
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.034
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.034
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
16 |
0.034
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.034
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.034
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.034
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.034
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.034
|
|
|
|
tolerance induction
|
GO:0002507 |
14 |
0.034
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.034
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.033
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.033
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.033
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.033
|
|
|
|
regulation of interferon gamma mediated signaling pathway
|
GO:0060334 |
3 |
0.033
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.033
|
|
|
|
specification of organ position
|
GO:0010159 |
3 |
0.033
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.033
|
|
|
|
endoderm development
|
GO:0007492 |
45 |
0.032
|
|
|
|
acute inflammatory response to antigenic stimulus
|
GO:0002438 |
12 |
0.032
|
|
|
|
negative regulation of lymphocyte apoptotic process
|
GO:0070229 |
24 |
0.032
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.032
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.032
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
31 |
0.032
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.032
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.032
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.032
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.032
|
|
|
|
inner cell mass cell proliferation
|
GO:0001833 |
15 |
0.032
|
Mouse |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.031
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.031
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.031
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.031
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
2 |
0.031
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.031
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.031
|
|
|
|
negative regulation of interleukin 2 production
|
GO:0032703 |
8 |
0.031
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.031
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.031
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.030
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.030
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.030
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.030
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.030
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.030
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.030
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.030
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.030
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.030
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.030
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.030
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.030
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.030
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.029
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.029
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.029
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.029
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.029
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.029
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.029
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.029
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.029
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.029
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor production
|
GO:0032725 |
3 |
0.029
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.029
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.029
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.029
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.028
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.028
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.028
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.028
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.028
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.028
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.028
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.028
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.028
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.028
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.028
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.028
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.028
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.028
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.028
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.028
|
|
|
|
myoblast differentiation
|
GO:0045445 |
52 |
0.028
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.027
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.027
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.027
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.027
|
|
|
|
visceral motor neuron differentiation
|
GO:0021524 |
3 |
0.027
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.027
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.027
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.027
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.026
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.026
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.026
|
|
|
|
regulation of t cell apoptotic process
|
GO:0070232 |
28 |
0.026
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.026
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.026
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.026
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.026
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
3 |
0.026
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.026
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.026
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.025
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.025
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.025
|
|
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
24 |
0.025
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.025
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.025
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.025
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.025
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.025
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.025
|
|
|
|
positive regulation of muscle tissue development
|
GO:1901863 |
32 |
0.025
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.025
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.025
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.025
|
|
|
|
positive regulation of t cell anergy
|
GO:0002669 |
4 |
0.025
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.024
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.024
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.024
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.024
|
|
