|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.801
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.741
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.562
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.545
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.544
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.540
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.464
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.407
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.398
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.352
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.322
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.300
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.296
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.286
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.284
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.282
|
|
|
|
regulation of lymphocyte anergy
|
GO:0002911 |
4 |
0.272
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.271
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.257
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.254
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.243
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.240
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.240
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.237
|
|
|
|
natural killer cell inhibitory signaling pathway
|
GO:0002769 |
2 |
0.234
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.232
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.225
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.225
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.214
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.204
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.203
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.195
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.192
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.191
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.188
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.185
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.184
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.183
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.181
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.180
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.178
|
Human |
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.175
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.172
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.172
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.170
|
|
|
|
positive regulation of lymphocyte anergy
|
GO:0002913 |
4 |
0.169
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.164
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.163
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.161
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.160
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.160
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.153
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.152
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.151
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.151
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.151
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.146
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.145
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.145
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.145
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.145
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.142
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.142
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.140
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.139
|
|
|
|
antigen processing and presentation of peptide antigen via mhc class ii
|
GO:0002495 |
17 |
0.134
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.134
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.132
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.129
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.129
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.128
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.128
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.125
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.123
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.123
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.122
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.121
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.117
|
Human |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.117
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.117
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.116
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.116
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.115
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.115
|
Human |
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.114
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.113
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.113
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.112
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.112
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.111
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.110
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.110
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.110
|
|
|
|
negative regulation of epidermal growth factor activated receptor activity
|
GO:0007175 |
3 |
0.108
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.108
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.107
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.106
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.105
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.105
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.103
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.103
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.103
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.102
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.102
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.101
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.101
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.100
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.099
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.099
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.099
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.099
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.098
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.098
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.097
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.097
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.096
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.096
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.096
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.096
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.095
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.095
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.094
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.093
|
|
|
|
positive regulation of t cell anergy
|
GO:0002669 |
4 |
0.092
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.092
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.091
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.090
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.090
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.090
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.090
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.090
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.090
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.090
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.089
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.088
|
|
|
|
t cell anergy
|
GO:0002870 |
4 |
0.088
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.088
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.086
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.085
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.084
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.084
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.083
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.082
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.082
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.082
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.081
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.081
|
|
|
|
granzyme mediated apoptotic signaling pathway
|
GO:0008626 |
1 |
0.080
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.080
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.080
|
|
|
|
lymphocyte anergy
|
GO:0002249 |
4 |
0.079
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.078
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.077
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.077
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.075
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.074
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.071
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.071
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.071
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.070
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.070
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.070
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.069
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.069
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.069
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.068
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.068
|
Human |
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.068
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.068
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.067
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.067
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.067
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.067
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.067
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.066
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.066
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.065
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.065
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.063
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.062
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.062
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.062
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.061
|
Human |
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.061
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.061
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.061
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.061
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.061
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.061
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.060
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.060
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.060
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.059
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.058
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.058
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.057
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
15 |
0.056
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.056
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.055
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.055
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.055
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.055
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.055
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.054
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.054
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.054
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.054
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.053
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.053
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.052
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.052
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.052
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.051
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.051
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.051
|
|
|
|
dendritic cell chemotaxis
|
GO:0002407 |
7 |
0.050
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.050
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.050
|
|
|
|
positive thymic t cell selection
|
GO:0045059 |
13 |
0.050
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.050
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.049
|
|
|
|
regulation of natural killer cell activation
|
GO:0032814 |
22 |
0.048
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.048
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.047
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.047
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.047
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.047
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.047
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.047
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.046
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.046
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.046
|
Human |
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.046
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.046
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.046
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.045
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.045
|
Human |
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.044
|
|
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.044
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.044
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.044
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.044
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.044
|
|
|
|
blastocyst growth
|
GO:0001832 |
23 |
0.044
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.044
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.044
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.044
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.043
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.043
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.043
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.043
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.043
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.043
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.043
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.042
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.042
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.042
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.042
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.042
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.042
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.042
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.041
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.041
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.041
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.040
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.040
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.040
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.040
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.040
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.040
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.040
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.040
|
|
|
|
antigen processing and presentation of exogenous peptide antigen via mhc class ii
|
GO:0019886 |
14 |
0.040
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.039
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.039
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
2 |
0.039
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.039
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.039
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.039
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.039
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.038
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.038
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.038
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.038
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.038
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.038
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.038
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.038
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.038
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.038
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.037
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.037
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.037
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.037
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.037
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.037
|
|
|
|
tolerance induction
|
GO:0002507 |
14 |
0.036
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.036
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.036
|
|
|
|
antigen processing and presentation of exogenous peptide antigen
|
GO:0002478 |
21 |
0.036
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.036
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.036
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.035
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.035
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.035
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.035
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.035
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.035
|
|
|
|
regulation of interleukin 2 biosynthetic process
|
GO:0045076 |
13 |
0.035
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.035
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.035
|
|
|
|
inner cell mass cell proliferation
|
GO:0001833 |
15 |
0.035
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.035
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.035
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.035
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.035
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.035
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.034
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.034
|
Human |
|
|
myeloid dendritic cell chemotaxis
|
GO:0002408 |
2 |
0.034
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.034
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.034
|
Human |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.034
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.034
|
|
|
|
positive regulation of immune complex clearance by monocytes and macrophages
|
GO:0090265 |
2 |
0.034
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.034
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.034
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.034
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.034
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.033
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.033
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.033
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.033
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.033
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.033
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
31 |
0.033
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.033
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.032
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.032
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.032
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.032
|
|
|
|
antigen processing and presentation of exogenous antigen
|
GO:0019884 |
26 |
0.032
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.032
|
Human |
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.032
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.032
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.032
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.032
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.032
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.032
|
Human |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.032
|
Human |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.032
|
|
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.032
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.031
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.031
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.031
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.031
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.031
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.031
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.031
|
Human |
|
|
positive regulation of t helper 1 cell cytokine production
|
GO:2000556 |
1 |
0.031
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.031
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.031
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.031
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.030
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.030
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.030
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.030
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.030
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.030
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.030
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.030
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.030
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.029
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.029
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.029
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.029
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.029
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.029
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.029
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.029
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.029
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.028
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.028
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.028
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.028
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.028
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.028
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.028
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.028
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.028
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.028
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.028
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.027
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.027
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.027
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.027
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.027
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.027
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.027
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.027
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.027
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.027
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.027
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.027
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
27 |
0.026
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.026
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.026
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.026
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.026
|
Human |
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.026
|
|
|
|
positive regulation of cardioblast differentiation
|
GO:0051891 |
3 |
0.026
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.026
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.026
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.026
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.026
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.026
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.026
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.026
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
3 |
0.026
|
Human |
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.025
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.025
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.025
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.025
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.025
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.025
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.025
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.025
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.025
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.025
|
Human |
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.025
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.025
|
|
|
|
sphingosine 1 phosphate signaling pathway
|
GO:0003376 |
3 |
0.025
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.024
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.024
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.024
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.024
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.024
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.024
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.024
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
25 |
0.024
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.024
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
25 |
0.024
|
|
|
|
renal sodium excretion
|
GO:0035812 |
3 |
0.024
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
17 |
0.024
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.024
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.024
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.024
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.024
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.024
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.024
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.024
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.023
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.023
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.023
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.023
|
|
|
|
positive regulation of tor signaling
|
GO:0032008 |
3 |
0.023
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.023
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
12 |
0.023
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
61 |
0.023
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.023
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.023
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.023
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.023
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.023
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.023
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.022
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.022
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.022
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.022
|
|
|
|
positive regulation of interleukin 2 biosynthetic process
|
GO:0045086 |
8 |
0.022
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.022
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.022
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.022
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.022
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.022
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.022
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.022
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.022
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.022
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.021
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.021
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.021
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.021
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.021
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.021
|
|
|
|
regulation of antigen processing and presentation
|
GO:0002577 |
10 |
0.021
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.021
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.021
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.021
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.021
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.021
|
|
