|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.477
|
Fly |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.359
|
Worm |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.298
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.289
|
|
|
|
positive regulation of t cell mediated cytotoxicity
|
GO:0001916 |
15 |
0.226
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.215
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.200
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.189
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.183
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.180
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.178
|
Fly |
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.163
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.159
|
Worm |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.159
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.153
|
Worm |
|
|
maintenance of location
|
GO:0051235 |
89 |
0.150
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.149
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.149
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.146
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
13 |
0.142
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.141
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.132
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.129
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.128
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.119
|
Worm |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.115
|
Worm |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.114
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.112
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.111
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.111
|
Worm |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.109
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.108
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.104
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.104
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.103
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.103
|
Fly |
|
|
vesicle localization
|
GO:0051648 |
86 |
0.098
|
Fly |
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.095
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.095
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.095
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.093
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.092
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.092
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.091
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.086
|
Fly |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.085
|
Worm |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.084
|
Worm |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.084
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.083
|
Worm |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.082
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.081
|
Human |
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.081
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.080
|
Fly |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.079
|
Fly |
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.079
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.078
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.078
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
57 |
0.078
|
Fly |
|
|
digestive system development
|
GO:0055123 |
200 |
0.078
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.078
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.077
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.076
|
Worm |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.076
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.075
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.075
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.075
|
|
|
|
satellite cell activation involved in skeletal muscle regeneration
|
GO:0014901 |
3 |
0.074
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.073
|
Worm |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.073
|
Worm |
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.073
|
Fly |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.072
|
Worm |
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.071
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.070
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.070
|
Fly |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.069
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.069
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.068
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.067
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.067
|
Worm |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.067
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.067
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.066
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.065
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.064
|
Fly |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.063
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.063
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.063
|
Worm |
|
|
response to fibroblast growth factor
|
GO:0071774 |
47 |
0.062
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.062
|
Worm |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.061
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.061
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.061
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.060
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.059
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.058
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.057
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.057
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.057
|
Human Rat Worm Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.057
|
Worm |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.055
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.055
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.054
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.054
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.054
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.054
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.053
|
Worm |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.052
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.052
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.052
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.052
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.052
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.051
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.051
|
Worm |
|
|
autophagy
|
GO:0006914 |
45 |
0.051
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.051
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.051
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.051
|
Worm |
|
|
lipid localization
|
GO:0010876 |
126 |
0.050
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.049
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.049
|
Fly |
|
|
endocytosis
|
GO:0006897 |
168 |
0.048
|
Human Mouse Rat Worm Fly |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.048
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.048
|
Worm |
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.048
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.048
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.047
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.047
|
Worm |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.047
|
Worm |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.047
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.047
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.046
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.046
|
Fly |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.045
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.045
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.044
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.044
|
Worm |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.043
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.043
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.043
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.043
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.043
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.043
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.042
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.042
|
Worm |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.042
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.041
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.041
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.041
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.041
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.041
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.041
|
Fly |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.040
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.040
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.040
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.040
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
19 |
0.040
|
Fly |
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.039
|
Fly |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.039
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.038
|
Worm |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.038
|
Worm |
|
|
response to insulin
|
GO:0032868 |
100 |
0.038
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.038
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.038
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.037
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.037
|
Fly |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.037
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.037
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.037
|
|
|
|
pigmentation
|
GO:0043473 |
71 |
0.037
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.036
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.036
|
Fly |
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.036
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.036
|
Worm |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.036
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.036
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.035
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.035
|
|
|
|
membrane tubulation
|
GO:0097320 |
4 |
0.035
|
Human |
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.034
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.034
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.034
|
Worm |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.034
|
Worm |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.034
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.034
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.033
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.033
|
Fly |
|
|
cellular response to salt stress
|
GO:0071472 |
1 |
0.033
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.033
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.032
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.032
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.032
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.032
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.032
|
Fly |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.032
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.032
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.032
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.031
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.031
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.031
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.031
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.030
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.030
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.030
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.030
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.030
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.030
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.030
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.030
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.030
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.030
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.030
|
|
|
|
negative regulation of erbb signaling pathway
|
GO:1901185 |
7 |
0.030
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.029
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.029
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.029
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.029
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.029
|
Worm |
|
|
negative regulation of macrophage activation
|
GO:0043031 |
2 |
0.029
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.028
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.028
|
Worm |
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.028
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.027
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.027
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.027
|
Worm |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.027
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.027
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
49 |
0.027
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.027
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.027
|
|
|
|
positive regulation of urine volume
|
GO:0035810 |
6 |
0.026
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
25 |
0.026
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.026
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.025
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.025
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.025
|
|
|
|
cytokinetic process
|
GO:0032506 |
2 |
0.025
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.025
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.025
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.025
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.025
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.025
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.025
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.025
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.024
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.024
|
|
|
|
glycosylation
|
GO:0070085 |
62 |
0.024
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.024
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.024
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.024
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
3 |
0.024
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.024
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.024
|
Worm |
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.024
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.024
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.024
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.023
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.023
|
Worm |
|
|
female gamete generation
|
GO:0007292 |
74 |
0.023
|
Fly |
|
|
male gamete generation
|
GO:0048232 |
285 |
0.023
|
Fly |
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.023
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.023
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.023
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.023
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.023
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.023
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.023
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.022
|
Worm |
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.022
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.022
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.022
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.022
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.022
|
Human Worm Fly |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.022
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.022
|
Worm |
|
|
actin mediated cell contraction
|
GO:0070252 |
15 |
0.022
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.021
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.021
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.021
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.021
|
Fly |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.021
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.021
|
|
|
|
regulation of satellite cell activation involved in skeletal muscle regeneration
|
GO:0014717 |
3 |
0.021
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.021
|
|
|
|
translation
|
GO:0006412 |
93 |
0.021
|
|
|
|
regulation of translational initiation
|
GO:0006446 |
15 |
0.021
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.021
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.021
|
|
|
|
phosphatidic acid metabolic process
|
GO:0046473 |
2 |
0.021
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.021
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.021
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.021
|
|
|
|
protein glycosylation
|
GO:0006486 |
55 |
0.021
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.021
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.021
|
|
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
6 |
0.021
|
|
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
18 |
0.020
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.020
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.020
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.020
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.020
|
Fly |
|
|
learning or memory
|
GO:0007611 |
148 |
0.020
|
Fly |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.020
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.020
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.020
|
|
|
|
exosomal secretion
|
GO:1990182 |
1 |
0.020
|
|
|
|
negative regulation of protein tyrosine kinase activity
|
GO:0061099 |
3 |
0.020
|
|
|
|
cardiac septum development
|
GO:0003279 |
59 |
0.020
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
7 |
0.020
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.020
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.020
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.020
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.020
|
|
|
|
regulation of urine volume
|
GO:0035809 |
6 |
0.019
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.019
|
Worm |
|
|
phosphatidic acid biosynthetic process
|
GO:0006654 |
2 |
0.019
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
30 |
0.019
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.019
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.019
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
47 |
0.019
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.019
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.019
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.019
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.019
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.019
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.018
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.018
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.018
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.018
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.018
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.018
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.018
|
Worm |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.018
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.018
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.018
|
Worm |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.017
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.017
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.017
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.017
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.017
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.017
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.017
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.017
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001267 |
4 |
0.017
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.017
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.017
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.017
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.017
|
|
|
|
transforming growth factor beta1 production
|
GO:0032905 |
3 |
0.017
|
|
|
|
lung cell differentiation
|
GO:0060479 |
30 |
0.017
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.017
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.017
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.017
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.017
|
|
|
|
establishment of protein localization to vacuole
|
GO:0072666 |
4 |
0.016
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.016
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
16 |
0.016
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.016
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.016
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.016
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.016
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.016
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.016
|
|
|
|
translational initiation
|
GO:0006413 |
24 |
0.016
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.016
|
Fly |
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.016
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.016
|
Worm |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.016
|
Worm |
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.016
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.016
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.016
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.016
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.016
|
|
|
|
ventricular cardiac muscle cell action potential
|
GO:0086005 |
4 |
0.016
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.016
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
30 |
0.016
|
|
|
|
directional locomotion
|
GO:0033058 |
3 |
0.016
|
|
|
|
negative regulation of t helper 1 cell differentiation
|
GO:0045626 |
3 |
0.016
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.016
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.016
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.016
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.015
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.015
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.015
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.015
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.015
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.015
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.015
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
2 |
0.015
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.015
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.015
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.015
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.015
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
4 |
0.015
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.015
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
80 |
0.015
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.015
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.014
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.014
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.014
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.014
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.014
|
Fly |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.014
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.014
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.014
|
Fly |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.014
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.014
|
|
|
|
protein localization to vacuole
|
GO:0072665 |
4 |
0.014
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.014
|
|
|
|
circadian temperature homeostasis
|
GO:0060086 |
2 |
0.014
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.014
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.014
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.014
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.014
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.014
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.014
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.014
|
|
|
|
rna processing
|
GO:0006396 |
105 |
0.014
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.014
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.014
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.014
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.014
|
Fly |
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.013
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.013
|
|
|
|
positive regulation of satellite cell activation involved in skeletal muscle regeneration
|
GO:0014718 |
2 |
0.013
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.013
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.013
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
4 |
0.013
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.013
|
Human Fly |
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.013
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.013
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.013
|
|
|
|
regulation of cell migration involved in sprouting angiogenesis
|
GO:0090049 |
4 |
0.013
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.013
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.013
|
Fly |
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.013
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.013
|
|
|
|
autolysis
|
GO:0001896 |
1 |
0.013
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.013
|
|
|
|
negative regulation of receptor activity
|
GO:2000272 |
5 |
0.013
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.013
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.013
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.013
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.013
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.013
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
55 |
0.013
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.013
|
|
|
|
learning
|
GO:0007612 |
98 |
0.013
|
Fly |
|
|
regulation of macrophage activation
|
GO:0043030 |
17 |
0.013
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.013
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.013
|
Worm |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.013
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.013
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.013
|
Fly |
|
|
phospholipid transfer to membrane
|
GO:0006649 |
2 |
0.013
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.013
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.013
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.013
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.012
|
|
|
|
activation of rac gtpase activity
|
GO:0032863 |
2 |
0.012
|
|
|
|
cell cycle switching mitotic to meiotic cell cycle
|
GO:0051728 |
1 |
0.012
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.012
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.012
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.012
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.012
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.012
|
Fly |
|
|
activation of ras gtpase activity
|
GO:0032856 |
11 |
0.012
|
|
|
|
sperm individualization
|
GO:0007291 |
1 |
0.012
|
Fly |
|
|
organelle fission
|
GO:0048285 |
170 |
0.012
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.012
|
Fly |
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.012
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.012
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.012
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.012
|
Worm Fly |
|
|
protein targeting to vacuole
|
GO:0006623 |
3 |
0.012
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.012
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.012
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.012
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.012
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.012
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.012
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.012
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
29 |
0.012
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.012
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.012
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.012
|
|
|
|
response to purine containing compound
|
GO:0014074 |
28 |
0.012
|
|
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
3 |
0.012
|
|
