Mus musculus

41 known processes

Eml4

echinoderm microtubule associated protein like 4

(Aliases: AI644019,MGC90779,4930443C24Rik)

Eml4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin organization GO:0006325 206 0.099
regulation of organelle organization GO:0033043 289 0.085
cellular amino acid metabolic process GO:0006520 103 0.073
regulation of cellular amino acid metabolic process GO:0006521 5 0.068
cellular ketone metabolic process GO:0042180 84 0.066
regulation of cellular amine metabolic process GO:0033238 20 0.064
cellular amine metabolic process GO:0044106 44 0.062
amine metabolic process GO:0009308 45 0.059
heterocycle catabolic process GO:0046700 280 0.057
cellular nitrogen compound catabolic process GO:0044270 280 0.056
covalent chromatin modification GO:0016569 163 0.052
dna metabolic process GO:0006259 303 0.051
regulation of cellular ketone metabolic process GO:0010565 66 0.049
macromolecule catabolic process GO:0009057 281 0.049
aromatic compound catabolic process GO:0019439 286 0.048
organic cyclic compound catabolic process GO:1901361 295 0.047
protein modification by small protein conjugation GO:0032446 187 0.045
small gtpase mediated signal transduction GO:0007264 97 0.043
chromatin modification GO:0016568 187 0.042
ras protein signal transduction GO:0007265 77 0.042
nucleobase containing small molecule metabolic process GO:0055086 352 0.042
regulation of cell cycle GO:0051726 281 0.041
peptidyl amino acid modification GO:0018193 336 0.040
purine containing compound metabolic process GO:0072521 311 0.040
negative regulation of cellular component organization GO:0051129 194 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
histone modification GO:0016570 159 0.039
methylation GO:0032259 134 0.039
carbohydrate derivative catabolic process GO:1901136 231 0.039
macromolecule methylation GO:0043414 120 0.038
protein modification by small protein conjugation or removal GO:0070647 207 0.038
nucleoside phosphate metabolic process GO:0006753 338 0.038
organelle fission GO:0048285 170 0.038
negative regulation of protein metabolic process GO:0051248 282 0.038
negative regulation of molecular function GO:0044092 258 0.037
ribose phosphate metabolic process GO:0019693 291 0.036
stem cell differentiation GO:0048863 268 0.034
ribonucleotide catabolic process GO:0009261 208 0.033
rna processing GO:0006396 105 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
cellular macromolecule catabolic process GO:0044265 206 0.031
apoptotic signaling pathway GO:0097190 306 0.031
organonitrogen compound catabolic process GO:1901565 264 0.030
histone lysine methylation GO:0034968 50 0.030
cytokine production GO:0001816 319 0.030
purine nucleotide catabolic process GO:0006195 211 0.030
negative regulation of cellular protein metabolic process GO:0032269 247 0.029
immune effector process GO:0002252 321 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
purine containing compound catabolic process GO:0072523 213 0.029
response to organonitrogen compound GO:0010243 246 0.029
purine nucleoside triphosphate catabolic process GO:0009146 203 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
ribonucleotide metabolic process GO:0009259 291 0.028
nucleoside metabolic process GO:0009116 246 0.028
myeloid cell differentiation GO:0030099 233 0.028
nucleotide metabolic process GO:0009117 332 0.028
regulation of cellular component biogenesis GO:0044087 181 0.028
nucleoside phosphate catabolic process GO:1901292 222 0.028
protein ubiquitination GO:0016567 171 0.027
cell adhesion GO:0007155 329 0.027
actin cytoskeleton organization GO:0030036 220 0.027
protein catabolic process GO:0030163 221 0.027
regulation of defense response GO:0031347 233 0.026
leukocyte differentiation GO:0002521 342 0.026
regulation of nucleotide metabolic process GO:0006140 169 0.026
meiotic cell cycle GO:0051321 122 0.026
regulation of cell activation GO:0050865 289 0.026
organophosphate catabolic process GO:0046434 232 0.026
skeletal system development GO:0001501 356 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
male gamete generation GO:0048232 285 0.025
regulation of neuron differentiation GO:0045664 281 0.025
mrna metabolic process GO:0016071 84 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
regulation of nucleotide catabolic process GO:0030811 122 0.025
glycosyl compound catabolic process GO:1901658 206 0.025
protein methylation GO:0006479 81 0.025
regulation of chromosome organization GO:0033044 83 0.025
regulation of lymphocyte activation GO:0051249 240 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
nuclear division GO:0000280 158 0.024
stem cell development GO:0048864 219 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
positive regulation of organelle organization GO:0010638 128 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.023
response to lipopolysaccharide GO:0032496 128 0.023
positive regulation of protein modification process GO:0031401 299 0.023
cellular lipid metabolic process GO:0044255 323 0.023
intracellular protein transport GO:0006886 204 0.023
nuclear transport GO:0051169 139 0.022
epithelial tube morphogenesis GO:0060562 303 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
negative regulation of organelle organization GO:0010639 90 0.022
histone methylation GO:0016571 71 0.022
nucleocytoplasmic transport GO:0006913 139 0.022
regulation of chromatin modification GO:1903308 57 0.022
gland development GO:0048732 330 0.022
mitotic cell cycle GO:0000278 195 0.022
Mouse
axonogenesis GO:0007409 274 0.022
cytoplasmic transport GO:0016482 234 0.022
compound eye development GO:0048749 1 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
regulation of protein localization GO:0032880 231 0.021
regulation of protein kinase activity GO:0045859 232 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
cellular response to lipid GO:0071396 145 0.021
regulation of anatomical structure size GO:0090066 178 0.021
cation transmembrane transport GO:0098655 266 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
positive regulation of nervous system development GO:0051962 221 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
positive regulation of cell development GO:0010720 237 0.021
camera type eye development GO:0043010 266 0.021
regulation of mapk cascade GO:0043408 248 0.021
t cell activation GO:0042110 289 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
nucleotide catabolic process GO:0009166 217 0.021
germ cell development GO:0007281 185 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.020
cell division GO:0051301 120 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
sensory perception GO:0007600 245 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
innate immune response GO:0045087 157 0.020
b cell activation GO:0042113 161 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
spermatogenesis GO:0007283 284 0.020
regulation of cytokine production GO:0001817 266 0.020
muscle cell differentiation GO:0042692 261 0.020
inflammatory response GO:0006954 244 0.020
mapk cascade GO:0000165 281 0.020
regulation of cell projection organization GO:0031344 206 0.020
microtubule cytoskeleton organization GO:0000226 157 0.020
homeostasis of number of cells GO:0048872 210 0.019
blood vessel morphogenesis GO:0048514 285 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
digestive system development GO:0055123 200 0.019
regionalization GO:0003002 337 0.019
transmembrane transport GO:0055085 412 0.019
protein maturation GO:0051604 176 0.019
cellular protein catabolic process GO:0044257 155 0.019
regulation of cell motility GO:2000145 236 0.019
multicellular organism growth GO:0035264 161 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
regulation of mitotic cell cycle GO:0007346 126 0.019
lipid biosynthetic process GO:0008610 179 0.018
ossification GO:0001503 216 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
stem cell maintenance GO:0019827 130 0.018
dendrite development GO:0016358 115 0.018
oocyte construction GO:0007308 2 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
negative regulation of protein modification process GO:0031400 163 0.018
regulation of chromatin organization GO:1902275 57 0.018
cell type specific apoptotic process GO:0097285 268 0.018
rho protein signal transduction GO:0007266 32 0.018
cation transport GO:0006812 399 0.018
regulation of cell migration GO:0030334 219 0.018
regulation of membrane potential GO:0042391 192 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.017
regulation of cell cycle process GO:0010564 160 0.017
cognition GO:0050890 149 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
action potential GO:0001508 78 0.017
nitrogen compound transport GO:0071705 271 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.017
regulation of proteolysis GO:0030162 164 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
endocytosis GO:0006897 168 0.017
lymphocyte proliferation GO:0046651 164 0.017
regulation of cellular response to stress GO:0080135 159 0.017
mitotic cell cycle process GO:1903047 159 0.017
Mouse
regulation of response to wounding GO:1903034 189 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
digestive tract development GO:0048565 190 0.017
lymphocyte differentiation GO:0030098 242 0.017
regulation of hormone levels GO:0010817 211 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
regulation of cell adhesion GO:0030155 154 0.016
respiratory system development GO:0060541 190 0.016
peptidyl lysine modification GO:0018205 77 0.016
sensory organ morphogenesis GO:0090596 242 0.016
meiotic nuclear division GO:0007126 115 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
regulation of transferase activity GO:0051338 263 0.016
regulation of secretion by cell GO:1903530 249 0.016
response to radiation GO:0009314 165 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
regulation of histone modification GO:0031056 56 0.016
protein targeting GO:0006605 143 0.016
regulation of histone methylation GO:0031060 30 0.016
striated muscle tissue development GO:0014706 293 0.016
response to organic cyclic compound GO:0014070 198 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
leukocyte proliferation GO:0070661 172 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
regulation of hydrolase activity GO:0051336 246 0.016
oocyte axis specification GO:0007309 2 0.016
regulation of protein complex assembly GO:0043254 83 0.016
epithelial cell development GO:0002064 159 0.016
protein localization to nucleus GO:0034504 121 0.016
wnt signaling pathway GO:0016055 188 0.015
cellular response to molecule of bacterial origin GO:0071219 83 0.015
positive regulation of mapk cascade GO:0043410 170 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
positive regulation of cell death GO:0010942 224 0.015
gastrulation GO:0007369 116 0.015
regulation of t cell activation GO:0050863 170 0.015
learning or memory GO:0007611 148 0.015
actin filament organization GO:0007015 113 0.015
cell fate commitment GO:0045165 210 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
negative regulation of immune system process GO:0002683 209 0.015
regulation of kinase activity GO:0043549 249 0.015
protein alkylation GO:0008213 81 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
digestive tract morphogenesis GO:0048546 147 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
protein import GO:0017038 101 0.015
activation of immune response GO:0002253 138 0.015
membrane organization GO:0061024 245 0.015
cellular protein complex assembly GO:0043623 116 0.015
regulation of multi organism process GO:0043900 111 0.015
regulation of system process GO:0044057 200 0.015
cellular homeostasis GO:0019725 240 0.015
regulation of cellular component size GO:0032535 121 0.015
regulation of neuron death GO:1901214 134 0.015
chemotaxis GO:0006935 247 0.015
lateral inhibition GO:0046331 1 0.015
regulation of cytoskeleton organization GO:0051493 122 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
oxidation reduction process GO:0055114 342 0.015
production of molecular mediator of immune response GO:0002440 103 0.015
circulatory system process GO:0003013 197 0.014
immune response regulating signaling pathway GO:0002764 125 0.014
regulation of inflammatory response GO:0050727 147 0.014
locomotory behavior GO:0007626 195 0.014
nucleoside catabolic process GO:0009164 206 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
developmental maturation GO:0021700 193 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
epithelial tube formation GO:0072175 130 0.014
leukocyte mediated immunity GO:0002443 174 0.014
intracellular mrna localization GO:0008298 4 0.014
neural tube development GO:0021915 160 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
negative regulation of cell development GO:0010721 169 0.014
response to light stimulus GO:0009416 135 0.014
regulation of homeostatic process GO:0032844 182 0.014
mrna processing GO:0006397 63 0.014
muscle tissue development GO:0060537 308 0.014
regulation of intracellular transport GO:0032386 159 0.014
b cell differentiation GO:0030183 78 0.014
t cell differentiation GO:0030217 174 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.014
regulation of secretion GO:0051046 274 0.014
spermatid differentiation GO:0048515 115 0.014
dna recombination GO:0006310 92 0.014
cellular chemical homeostasis GO:0055082 215 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
skin development GO:0043588 220 0.014
forebrain development GO:0030900 302 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
synapse organization GO:0050808 125 0.014
regulation of protein transport GO:0051223 163 0.014
multicellular organismal signaling GO:0035637 91 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.014
tube formation GO:0035148 140 0.014
neuronal action potential GO:0019228 54 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
transmission of nerve impulse GO:0019226 76 0.013
myeloid cell homeostasis GO:0002262 114 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
organelle assembly GO:0070925 177 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
positive regulation of cell activation GO:0050867 158 0.013
interspecies interaction between organisms GO:0044419 83 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
protein processing GO:0016485 163 0.013
neuron death GO:0070997 154 0.013
protein import into nucleus GO:0006606 95 0.013
neural tube formation GO:0001841 108 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
cation homeostasis GO:0055080 212 0.013
regulation of cell division GO:0051302 76 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
regulation of actin filament based process GO:0032970 99 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
connective tissue development GO:0061448 179 0.013
response to growth factor GO:0070848 198 0.013
respiratory tube development GO:0030323 167 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
maintenance of location GO:0051235 89 0.013
regulation of protein catabolic process GO:0042176 108 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
cell activation involved in immune response GO:0002263 126 0.013
negative regulation of nervous system development GO:0051961 156 0.013
response to oxidative stress GO:0006979 123 0.012
regulation of nuclear division GO:0051783 56 0.012
protein localization to organelle GO:0033365 185 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
response to extracellular stimulus GO:0009991 127 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
ion transmembrane transport GO:0034220 361 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
adaptive immune response GO:0002250 155 0.012
neuron apoptotic process GO:0051402 142 0.012
lung development GO:0030324 164 0.012
bone development GO:0060348 120 0.012
gtp metabolic process GO:0046039 144 0.012
ear development GO:0043583 200 0.012
spermatid development GO:0007286 108 0.012
blood circulation GO:0008015 195 0.012
cellular ion homeostasis GO:0006873 165 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
negative regulation of cell cycle GO:0045786 123 0.012
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
negative regulation of transferase activity GO:0051348 85 0.012
blastocyst development GO:0001824 80 0.012
retina development in camera type eye GO:0060041 119 0.012
regulation of innate immune response GO:0045088 91 0.011
regulation of neuron projection development GO:0010975 169 0.011
wound healing GO:0042060 157 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
alcohol metabolic process GO:0006066 116 0.011
carbohydrate metabolic process GO:0005975 230 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
mitotic nuclear division GO:0007067 48 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
rhythmic process GO:0048511 174 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
regulation of map kinase activity GO:0043405 120 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
microtubule based process GO:0007017 236 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
response to insulin GO:0032868 100 0.011
divalent metal ion transport GO:0070838 172 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
neuron migration GO:0001764 122 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
immune response activating signal transduction GO:0002757 116 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
divalent inorganic cation transport GO:0072511 178 0.011
endomembrane system organization GO:0010256 147 0.011
glycerolipid metabolic process GO:0046486 122 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
carbohydrate homeostasis GO:0033500 128 0.011
positive regulation of cytokine production GO:0001819 174 0.011
cardiac chamber morphogenesis GO:0003206 93 0.011
protein polymerization GO:0051258 57 0.011
dna repair GO:0006281 107 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
single organism cell adhesion GO:0098602 156 0.011
fat cell differentiation GO:0045444 160 0.011
organelle localization GO:0051640 179 0.011
response to inorganic substance GO:0010035 96 0.011
glucose homeostasis GO:0042593 128 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
regulation of protein maturation GO:1903317 96 0.011
mitochondrion organization GO:0007005 134 0.010
pole plasm assembly GO:0007315 2 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010
defense response to other organism GO:0098542 197 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
skeletal system morphogenesis GO:0048705 203 0.010
anatomical structure homeostasis GO:0060249 145 0.010
glycoprotein metabolic process GO:0009100 116 0.010
positive regulation of defense response GO:0031349 124 0.010
response to peptide GO:1901652 136 0.010
regulation of organ morphogenesis GO:2000027 144 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
response to peptide hormone GO:0043434 127 0.010
histone h3 k4 methylation GO:0051568 23 0.010
somatic cell dna recombination GO:0016444 51 0.010
peptidyl lysine methylation GO:0018022 29 0.010
nuclear import GO:0051170 95 0.010
epidermis development GO:0008544 187 0.010

Eml4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.023
cancer DOID:162 0 0.022
organ system cancer DOID:0050686 0 0.022
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018