Mus musculus

80 known processes

Ppt1

palmitoyl-protein thioesterase 1

(Aliases: MGC107420,AA960502,9530043G02Rik,C77813,CLN1,PPT,D4Ertd184e,INCL)

Ppt1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
peripheral nervous system axon regeneration GO:0014012 2 0.455
intermediate filament bundle assembly GO:0045110 3 0.354
positive regulation of glial cell proliferation GO:0060252 4 0.314
microtubule based movement GO:0007018 84 0.309
neurofilament cytoskeleton organization GO:0060052 10 0.308
microtubule based transport GO:0010970 50 0.236
cytoskeleton dependent intracellular transport GO:0030705 50 0.161
negative regulation of neuron death GO:1901215 98 0.148
cellular response to growth factor stimulus GO:0071363 197 0.120
neuron apoptotic process GO:0051402 142 0.109
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.108
schwann cell proliferation GO:0014010 2 0.103
intermediate filament based process GO:0045103 27 0.098
axon cargo transport GO:0008088 33 0.096
transmembrane transport GO:0055085 412 0.096
regulation of schwann cell proliferation GO:0010624 2 0.096
negative regulation of cellular component organization GO:0051129 194 0.088
negative regulation of cell development GO:0010721 169 0.085
negative regulation of cell projection organization GO:0031345 56 0.082
regulation of anatomical structure size GO:0090066 178 0.077
cell type specific apoptotic process GO:0097285 268 0.077
long term synaptic potentiation GO:0060291 25 0.073
camera type eye development GO:0043010 266 0.073
neuromuscular process controlling balance GO:0050885 59 0.070
cellular lipid metabolic process GO:0044255 323 0.068
regulation of cellular component size GO:0032535 121 0.066
regulation of neuron projection development GO:0010975 169 0.066
Fly
response to vitamin d GO:0033280 3 0.066
neuromuscular process GO:0050905 99 0.066
cellular amino acid metabolic process GO:0006520 103 0.065
regulation of neuron apoptotic process GO:0043523 122 0.064
positive regulation of neuron projection development GO:0010976 79 0.062
neurotransmitter uptake GO:0001504 14 0.061
neurotransmitter transport GO:0006836 76 0.060
negative regulation of neuron projection development GO:0010977 50 0.060
macromolecule catabolic process GO:0009057 281 0.059
negative regulation of protein metabolic process GO:0051248 282 0.055
response to growth factor GO:0070848 198 0.054
intermediate filament cytoskeleton organization GO:0045104 26 0.052
cellular ketone metabolic process GO:0042180 84 0.051
regulation of neuron death GO:1901214 134 0.050
ion transmembrane transport GO:0034220 361 0.049
glial cell differentiation GO:0010001 131 0.048
regulation of neurotransmitter uptake GO:0051580 6 0.048
cellular amine metabolic process GO:0044106 44 0.047
amine metabolic process GO:0009308 45 0.047
regulation of cell projection organization GO:0031344 206 0.046
Fly
negative regulation of neuron apoptotic process GO:0043524 92 0.046
neuron projection regeneration GO:0031102 14 0.045
membrane organization GO:0061024 245 0.045
negative regulation of nervous system development GO:0051961 156 0.045
glial cell development GO:0021782 54 0.045
positive regulation of neuron differentiation GO:0045666 141 0.045
decidualization GO:0046697 10 0.044
positive regulation of cell projection organization GO:0031346 95 0.044
lytic vacuole organization GO:0080171 21 0.044
regulation of cellular amine metabolic process GO:0033238 20 0.043
regulation of cell migration GO:0030334 219 0.040
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.040
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.039
extracellular matrix organization GO:0030198 147 0.039
cation transport GO:0006812 399 0.039
regulation of neuron differentiation GO:0045664 281 0.039
Fly
axonogenesis GO:0007409 274 0.039
Fly
smad protein signal transduction GO:0060395 21 0.038
regulation of synaptic plasticity GO:0048167 87 0.038
fat cell differentiation GO:0045444 160 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
cellular homeostasis GO:0019725 240 0.037
peripheral nervous system neuron axonogenesis GO:0048936 3 0.037
dna metabolic process GO:0006259 303 0.037
neuron death GO:0070997 154 0.037
positive regulation of cell development GO:0010720 237 0.037
extracellular structure organization GO:0043062 148 0.037
positive regulation of gliogenesis GO:0014015 27 0.036
nitrogen compound transport GO:0071705 271 0.036
gliogenesis GO:0042063 141 0.036
cation transmembrane transport GO:0098655 266 0.035
response to organic cyclic compound GO:0014070 198 0.035
protein maturation GO:0051604 176 0.034
positive regulation of schwann cell proliferation GO:0010625 1 0.034
cell adhesion GO:0007155 329 0.033
protein catabolic process GO:0030163 221 0.033
peptidyl amino acid modification GO:0018193 336 0.032
wound healing GO:0042060 157 0.032
regulation of cellular ketone metabolic process GO:0010565 66 0.032
sensory perception GO:0007600 245 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
response to radiation GO:0009314 165 0.031
inorganic ion transmembrane transport GO:0098660 234 0.031
response to alcohol GO:0097305 48 0.031
ras protein signal transduction GO:0007265 77 0.030
protein modification by small protein conjugation or removal GO:0070647 207 0.030
regulation of cytokine production GO:0001817 266 0.030
apoptotic signaling pathway GO:0097190 306 0.030
endomembrane system organization GO:0010256 147 0.030
regulation of cell projection size GO:0032536 6 0.030
regulation of transmembrane transport GO:0034762 128 0.030
regulation of apoptotic signaling pathway GO:2001233 197 0.029
placenta development GO:0001890 140 0.029
regulation of cell motility GO:2000145 236 0.028
negative regulation of molecular function GO:0044092 258 0.028
small gtpase mediated signal transduction GO:0007264 97 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.027
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.027
regulation of mapk cascade GO:0043408 248 0.027
microtubule based process GO:0007017 236 0.027
nuclear division GO:0000280 158 0.027
reactive oxygen species metabolic process GO:0072593 84 0.026
blood circulation GO:0008015 195 0.026
regulation of gliogenesis GO:0014013 50 0.026
astrocyte development GO:0014002 12 0.026
regulation of transferase activity GO:0051338 263 0.026
lens development in camera type eye GO:0002088 62 0.025
maternal process involved in female pregnancy GO:0060135 32 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
astrocyte differentiation GO:0048708 43 0.025
peripheral nervous system development GO:0007422 53 0.024
organic anion transport GO:0015711 137 0.024
regulation of cell activation GO:0050865 289 0.024
chemotaxis GO:0006935 247 0.024
Fly
anion transport GO:0006820 177 0.024
maternal placenta development GO:0001893 20 0.024
interleukin 8 production GO:0032637 4 0.024
heterocycle catabolic process GO:0046700 280 0.024
epithelial cell development GO:0002064 159 0.024
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
regulation of membrane potential GO:0042391 192 0.023
synaptic transmission GO:0007268 329 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
fertilization GO:0009566 127 0.023
monocarboxylic acid metabolic process GO:0032787 191 0.023
regulation of neurotransmitter transport GO:0051588 35 0.023
response to organonitrogen compound GO:0010243 246 0.022
regulation of protein transport GO:0051223 163 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.022
phospholipid metabolic process GO:0006644 87 0.022
regulation of kinase activity GO:0043549 249 0.022
regulation of protein localization GO:0032880 231 0.022
organelle assembly GO:0070925 177 0.022
cellular ion homeostasis GO:0006873 165 0.021
regulation of ion transmembrane transport GO:0034765 119 0.020
membrane lipid metabolic process GO:0006643 53 0.020
response to inorganic substance GO:0010035 96 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
regulation of wnt signaling pathway GO:0030111 123 0.020
multicellular organismal signaling GO:0035637 91 0.020
leukocyte activation involved in immune response GO:0002366 126 0.020
homeostasis of number of cells GO:0048872 210 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
nuclear transport GO:0051169 139 0.019
circulatory system process GO:0003013 197 0.019
response to peptide GO:1901652 136 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
peptidyl tyrosine phosphorylation GO:0018108 143 0.019
actin cytoskeleton organization GO:0030036 220 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
lipid localization GO:0010876 126 0.019
sphingolipid metabolic process GO:0006665 45 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
canonical wnt signaling pathway GO:0060070 130 0.018
regulation of cellular response to stress GO:0080135 159 0.018
cellular calcium ion homeostasis GO:0006874 119 0.018
lysosome organization GO:0007040 21 0.018
regeneration GO:0031099 38 0.018
protein localization to organelle GO:0033365 185 0.018
skeletal muscle tissue regeneration GO:0043403 20 0.018
blood coagulation GO:0007596 76 0.018
regulation of system process GO:0044057 200 0.018
response to transforming growth factor beta GO:0071559 88 0.018
regulation of ion transport GO:0043269 215 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
regulation of intracellular transport GO:0032386 159 0.018
cellular response to lipid GO:0071396 145 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.018
maintenance of location GO:0051235 89 0.017
bergmann glial cell differentiation GO:0060020 6 0.017
vacuole organization GO:0007033 38 0.017
cellular chemical homeostasis GO:0055082 215 0.017
carbohydrate metabolic process GO:0005975 230 0.017
carboxylic acid transport GO:0046942 100 0.017
innate immune response GO:0045087 157 0.017
regulation of ion transmembrane transporter activity GO:0032412 54 0.017
male gamete generation GO:0048232 285 0.017
divalent metal ion transport GO:0070838 172 0.017
cell growth GO:0016049 130 0.017
positive regulation of transferase activity GO:0051347 167 0.017
gonad development GO:0008406 141 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
peripheral nervous system neuron differentiation GO:0048934 9 0.017
positive regulation of kinase activity GO:0033674 155 0.017
glycerolipid metabolic process GO:0046486 122 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
positive regulation of nervous system development GO:0051962 221 0.016
multi multicellular organism process GO:0044706 109 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
rho protein signal transduction GO:0007266 32 0.016
spermatogenesis GO:0007283 284 0.016
negative regulation of wnt signaling pathway GO:0030178 73 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
regulation of voltage gated calcium channel activity GO:1901385 4 0.016
striated muscle tissue development GO:0014706 293 0.016
cellular response to dna damage stimulus GO:0006974 207 0.016
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.016
germ cell development GO:0007281 185 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
cell activation involved in immune response GO:0002263 126 0.016
mapk cascade GO:0000165 281 0.016
calcium ion homeostasis GO:0055074 127 0.016
glycerophospholipid metabolic process GO:0006650 71 0.016
lipid biosynthetic process GO:0008610 179 0.016
learning or memory GO:0007611 148 0.016
protein targeting GO:0006605 143 0.016
signal transduction in absence of ligand GO:0038034 55 0.016
second messenger mediated signaling GO:0019932 73 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.015
response to steroid hormone GO:0048545 56 0.015
aromatic compound catabolic process GO:0019439 286 0.015
protein ubiquitination GO:0016567 171 0.015
negative regulation of protein modification process GO:0031400 163 0.015
regulation of secretion GO:0051046 274 0.015
lipid catabolic process GO:0016042 69 0.015
response to extracellular stimulus GO:0009991 127 0.015
leukocyte differentiation GO:0002521 342 0.015
oxidation reduction process GO:0055114 342 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
regulation of organelle organization GO:0033043 289 0.015
b cell activation GO:0042113 161 0.015
stem cell differentiation GO:0048863 268 0.015
protein localization to membrane GO:0072657 108 0.015
regulation of homeostatic process GO:0032844 182 0.015
protein localization to plasma membrane GO:0072659 57 0.015
regulation of response to wounding GO:1903034 189 0.015
regulation of body fluid levels GO:0050878 162 0.015
wnt signaling pathway GO:0016055 188 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
spermatid development GO:0007286 108 0.015
glycoprotein metabolic process GO:0009100 116 0.014
muscle system process GO:0003012 141 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
cell matrix adhesion GO:0007160 68 0.014
leukocyte proliferation GO:0070661 172 0.014
meiotic cell cycle GO:0051321 122 0.014
neuronal action potential GO:0019228 54 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
axon regeneration GO:0031103 12 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
cell chemotaxis GO:0060326 81 0.014
cellular protein complex assembly GO:0043623 116 0.014
cellular lipid catabolic process GO:0044242 52 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
anatomical structure homeostasis GO:0060249 145 0.014
i kappab kinase nf kappab signaling GO:0007249 85 0.014
protein processing GO:0016485 163 0.014
regulation of protein processing GO:0070613 96 0.014
regulation of t cell activation GO:0050863 170 0.014
response to nutrient levels GO:0031667 109 0.014
nucleobase containing small molecule metabolic process GO:0055086 352 0.014
smoothened signaling pathway GO:0007224 105 0.014
purine containing compound metabolic process GO:0072521 311 0.014
response to peptide hormone GO:0043434 127 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
organelle fission GO:0048285 170 0.013
negative regulation of cytokine production GO:0001818 84 0.013
microglia differentiation GO:0014004 2 0.013
regulation of axon diameter GO:0031133 6 0.013
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.013
meiotic nuclear division GO:0007126 115 0.013
cation homeostasis GO:0055080 212 0.013
positive regulation of defense response GO:0031349 124 0.013
transmission of nerve impulse GO:0019226 76 0.013
calcium ion transport GO:0006816 159 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
response to oxidative stress GO:0006979 123 0.013
regulation of systemic arterial blood pressure GO:0003073 61 0.013
development of primary sexual characteristics GO:0045137 143 0.013
regulation of transporter activity GO:0032409 57 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
cytokine production GO:0001816 319 0.013
skeletal system development GO:0001501 356 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
cell recognition GO:0008037 83 0.013
endocytosis GO:0006897 168 0.013
Fly
amide transport GO:0042886 138 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
leukocyte chemotaxis GO:0030595 69 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
regulation of cell growth GO:0001558 91 0.013
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.013
cytoplasmic transport GO:0016482 234 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
organelle localization GO:0051640 179 0.012
Fly
nucleotide metabolic process GO:0009117 332 0.012
regulation of protein kinase activity GO:0045859 232 0.012
regulation of metal ion transport GO:0010959 106 0.012
intracellular protein transport GO:0006886 204 0.012
ear development GO:0043583 200 0.012
sulfur compound metabolic process GO:0006790 100 0.012
monosaccharide metabolic process GO:0005996 106 0.012
nucleoside catabolic process GO:0009164 206 0.012
chromatin organization GO:0006325 206 0.012
nuclear import GO:0051170 95 0.012
immune effector process GO:0002252 321 0.012
l amino acid transport GO:0015807 32 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
regulation of glial cell proliferation GO:0060251 8 0.012
angiogenesis GO:0001525 201 0.012
skeletal muscle organ development GO:0060538 163 0.012
hemostasis GO:0007599 78 0.012
sequestering of metal ion GO:0051238 19 0.012
small molecule biosynthetic process GO:0044283 132 0.012
kidney development GO:0001822 213 0.012
regulation of secretion by cell GO:1903530 249 0.012
regulation of interleukin 8 production GO:0032677 3 0.012
sensory organ morphogenesis GO:0090596 242 0.012
fatty acid metabolic process GO:0006631 121 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
spindle assembly involved in mitosis GO:0090307 4 0.012
cell cell recognition GO:0009988 44 0.012
regulation of cellular response to growth factor stimulus GO:0090287 82 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
transepithelial chloride transport GO:0030321 4 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
heart contraction GO:0060047 93 0.012
glial cell migration GO:0008347 7 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
compound eye development GO:0048749 1 0.012
single organismal cell cell adhesion GO:0016337 131 0.012
ceramide metabolic process GO:0006672 31 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
positive regulation of programmed cell death GO:0043068 218 0.011
urogenital system development GO:0001655 261 0.011
plasma membrane organization GO:0007009 90 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
phosphatidylinositol metabolic process GO:0046488 45 0.011
organophosphate catabolic process GO:0046434 232 0.011
leukocyte migration GO:0050900 124 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
dna repair GO:0006281 107 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
positive regulation of cell adhesion GO:0045785 80 0.011
response to lipopolysaccharide GO:0032496 128 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
peptidyl serine phosphorylation GO:0018105 74 0.011
ameboidal type cell migration GO:0001667 128 0.011
regulation of cell cycle GO:0051726 281 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
intermediate filament organization GO:0045109 15 0.011
cognition GO:0050890 149 0.011
protein autophosphorylation GO:0046777 61 0.011
protein oligomerization GO:0051259 67 0.011
lymphocyte differentiation GO:0030098 242 0.011
lipid transport GO:0006869 98 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
response to oxygen levels GO:0070482 62 0.011
regulation of leukocyte mediated immunity GO:0002703 104 0.011
positive regulation of interleukin 8 production GO:0032757 2 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
monovalent inorganic cation homeostasis GO:0055067 33 0.011
anion transmembrane transport GO:0098656 71 0.011
neuron migration GO:0001764 122 0.011
dephosphorylation GO:0016311 129 0.011
small molecule catabolic process GO:0044282 71 0.011
leukocyte mediated immunity GO:0002443 174 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
inflammatory response GO:0006954 244 0.011
regulation of blood vessel size GO:0050880 56 0.011
negative regulation of phagocytosis GO:0050765 4 0.011
regulation of nucleocytoplasmic transport GO:0046822 73 0.010
regulation of protein catabolic process GO:0042176 108 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
organic acid biosynthetic process GO:0016053 86 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010
sodium ion transport GO:0006814 73 0.010
lipid modification GO:0030258 65 0.010
negative regulation of protein maturation GO:1903318 79 0.010
gland development GO:0048732 330 0.010
posttranscriptional regulation of gene expression GO:0010608 155 0.010
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.010
alcohol metabolic process GO:0006066 116 0.010
organ regeneration GO:0031100 2 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
response to zinc ion GO:0010043 5 0.010
cofactor transport GO:0051181 4 0.010
inorganic anion transport GO:0015698 43 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.010
locomotory behavior GO:0007626 195 0.010
g protein coupled receptor signaling pathway GO:0007186 243 0.010

Ppt1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.062
nervous system disease DOID:863 0 0.062
central nervous system disease DOID:331 0 0.047
disease of metabolism DOID:0014667 0 0.045
inherited metabolic disorder DOID:655 0 0.040
lysosomal storage disease DOID:3211 0 0.029
brain disease DOID:936 0 0.028
sensory system disease DOID:0050155 0 0.021
eye and adnexa disease DOID:1492 0 0.021
eye disease DOID:5614 0 0.016
retinal disease DOID:5679 0 0.016
retinal degeneration DOID:8466 0 0.016
immune system disease DOID:2914 0 0.015
bone disease DOID:0080001 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
cerebral degeneration DOID:1443 0 0.014