Mus musculus

96 known processes

Gdf3

growth differentiation factor 3

(Aliases: Gdf-3,MGC123990,Vgr2,ecat9,MGC123991,C78318,Vgr-2)

Gdf3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
urogenital system development GO:0001655 261 0.959
Mouse Fly
mesendoderm development GO:0048382 3 0.900
skeletal system morphogenesis GO:0048705 203 0.896
Mouse
tendon formation GO:0035992 4 0.859
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.854
Mouse
primary neural tube formation GO:0014020 95 0.850
Mouse
appendage morphogenesis GO:0035107 149 0.847
Mouse Fly
endochondral bone morphogenesis GO:0060350 50 0.809
Mouse
regulation of organ morphogenesis GO:2000027 144 0.808
Mouse
adaptive immune response GO:0002250 155 0.782
neural tube development GO:0021915 160 0.757
Mouse
embryonic skeletal system development GO:0048706 120 0.741
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.738
Mouse
biomineral tissue development GO:0031214 64 0.735
Mouse
negative regulation of prostatic bud formation GO:0060686 4 0.729
Mouse
renal system development GO:0072001 225 0.718
Mouse Fly
immune effector process GO:0002252 321 0.714
regionalization GO:0003002 337 0.707
leukocyte differentiation GO:0002521 342 0.677
anion transport GO:0006820 177 0.667
morphogenesis of a branching epithelium GO:0061138 193 0.652
Mouse
forebrain development GO:0030900 302 0.648
Mouse
response to growth factor GO:0070848 198 0.647
Mouse
hindlimb morphogenesis GO:0035137 42 0.636
Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.633
Mouse
amine metabolic process GO:0009308 45 0.595
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.584
limb development GO:0060173 166 0.583
Mouse
b cell activation GO:0042113 161 0.573
skeletal system development GO:0001501 356 0.552
Mouse
appendage development GO:0048736 166 0.548
Mouse Fly
t cell activation GO:0042110 289 0.537
mechanoreceptor differentiation GO:0042490 67 0.533
Mouse
positive regulation of cell activation GO:0050867 158 0.532
bmp signaling pathway GO:0030509 93 0.528
Mouse Fly
positive regulation of lymphocyte activation GO:0051251 140 0.527
branching morphogenesis of an epithelial tube GO:0048754 159 0.525
Mouse
stem cell differentiation GO:0048863 268 0.515
Mouse Fly
neural tube closure GO:0001843 90 0.511
Mouse
b cell activation involved in immune response GO:0002312 50 0.506
cellular metal ion homeostasis GO:0006875 151 0.506
embryonic limb morphogenesis GO:0030326 126 0.494
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.491
angiogenesis GO:0001525 201 0.481
Mouse
forebrain regionalization GO:0021871 25 0.476
Mouse
production of molecular mediator of immune response GO:0002440 103 0.474
cellular amine metabolic process GO:0044106 44 0.471
bone development GO:0060348 120 0.469
Mouse
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.463
epithelial cell proliferation GO:0050673 174 0.454
Mouse
blood vessel morphogenesis GO:0048514 285 0.447
Mouse
axial mesodermal cell fate commitment GO:0048322 1 0.447
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.444
regulation of cell activation GO:0050865 289 0.442
embryonic epithelial tube formation GO:0001838 130 0.431
Mouse
defense response to other organism GO:0098542 197 0.418
positive regulation of epithelial cell proliferation GO:0050679 68 0.411
Mouse
cell fate commitment GO:0045165 210 0.410
Mouse Fly
odontogenesis GO:0042476 78 0.408
Mouse
cellular ion homeostasis GO:0006873 165 0.405
lymphocyte mediated immunity GO:0002449 139 0.403
digestive system development GO:0055123 200 0.401
epithelial tube morphogenesis GO:0060562 303 0.396
Mouse Fly
diencephalon development GO:0021536 63 0.393
Mouse
embryonic heart tube development GO:0035050 65 0.385
Mouse
lymphocyte activation involved in immune response GO:0002285 93 0.380
defense response to gram positive bacterium GO:0050830 50 0.380
oxidation reduction process GO:0055114 342 0.366
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.366
Mouse
sensory organ morphogenesis GO:0090596 242 0.360
Mouse Fly
limb morphogenesis GO:0035108 149 0.359
Mouse
intracellular receptor signaling pathway GO:0030522 74 0.356
regulation of embryonic development GO:0045995 71 0.349
Mouse
positive regulation of stem cell differentiation GO:2000738 23 0.346
Mouse
b cell mediated immunity GO:0019724 71 0.339
smad protein signal transduction GO:0060395 21 0.337
Mouse
endoderm development GO:0007492 45 0.335
leukocyte activation involved in immune response GO:0002366 126 0.333
morphogenesis of a branching structure GO:0001763 203 0.331
Mouse
neural tube formation GO:0001841 108 0.328
Mouse
myoblast differentiation GO:0045445 52 0.327
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.325
Mouse
deltoid tuberosity development GO:0035993 3 0.313
Mouse
striated muscle tissue development GO:0014706 293 0.309
mesenchymal cell development GO:0014031 93 0.307
Mouse
embryonic organ morphogenesis GO:0048562 276 0.304
Mouse
regulation of adaptive immune response GO:0002819 90 0.302
gland development GO:0048732 330 0.300
Mouse Fly
nephron development GO:0072006 109 0.297
Mouse
regulation of mapk cascade GO:0043408 248 0.296
Mouse
ossification GO:0001503 216 0.295
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.295
myotube differentiation GO:0014902 105 0.295
glomerulus development GO:0032835 40 0.291
Mouse
mesenchyme morphogenesis GO:0072132 32 0.290
Mouse
cation homeostasis GO:0055080 212 0.283
iron ion homeostasis GO:0055072 36 0.283
determination of left right symmetry GO:0007368 80 0.282
heart valve development GO:0003170 23 0.282
Mouse
leukocyte mediated immunity GO:0002443 174 0.281
central nervous system neuron differentiation GO:0021953 162 0.279
cellular response to lipid GO:0071396 145 0.276
regulation of cytokine production GO:0001817 266 0.275
kidney development GO:0001822 213 0.274
Mouse
dna metabolic process GO:0006259 303 0.271
digestive tract morphogenesis GO:0048546 147 0.268
kidney epithelium development GO:0072073 121 0.266
Mouse
axial mesodermal cell fate specification GO:0048327 1 0.265
cation transport GO:0006812 399 0.264
regulation of epithelial cell proliferation GO:0050678 141 0.264
Mouse
astrocyte differentiation GO:0048708 43 0.262
Mouse
blastocyst development GO:0001824 80 0.261
inner ear receptor cell differentiation GO:0060113 61 0.260
Mouse
erythrocyte differentiation GO:0030218 88 0.259
Mouse
forelimb morphogenesis GO:0035136 40 0.257
regulation of fat cell differentiation GO:0045598 81 0.257
Mouse
mapk cascade GO:0000165 281 0.253
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.249
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.247
stem cell maintenance GO:0019827 130 0.247
Fly
cartilage development GO:0051216 140 0.244
Mouse
muscle tissue morphogenesis GO:0060415 53 0.243
Mouse
cellular homeostasis GO:0019725 240 0.241
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.240
mesenchymal cell differentiation GO:0048762 107 0.239
Mouse
epithelial tube formation GO:0072175 130 0.235
Mouse
odontogenesis of dentin containing tooth GO:0042475 66 0.232
Mouse
cell type specific apoptotic process GO:0097285 268 0.232
camera type eye development GO:0043010 266 0.230
Mouse
pericardium development GO:0060039 16 0.230
Mouse
formation of primary germ layer GO:0001704 77 0.229
Mouse
myeloid cell differentiation GO:0030099 233 0.224
Mouse
forebrain neuron differentiation GO:0021879 52 0.223
embryonic placenta development GO:0001892 98 0.222
mesoderm formation GO:0001707 62 0.221
Mouse
determination of heart left right asymmetry GO:0061371 48 0.220
leukocyte migration GO:0050900 124 0.219
glial cell differentiation GO:0010001 131 0.218
Mouse
germ cell development GO:0007281 185 0.217
Mouse Fly
replacement ossification GO:0036075 26 0.214
Mouse
developmental maturation GO:0021700 193 0.211
Fly
head morphogenesis GO:0060323 34 0.208
divalent inorganic cation transport GO:0072511 178 0.208
regulation of lymphocyte mediated immunity GO:0002706 84 0.206
cytokine production GO:0001816 319 0.205
positive regulation of protein modification process GO:0031401 299 0.202
Mouse
cell activation involved in immune response GO:0002263 126 0.202
endodermal cell fate specification GO:0001714 4 0.200
muscle cell development GO:0055001 133 0.198
trachea formation GO:0060440 3 0.198
Mouse
lipid transport GO:0006869 98 0.196
telencephalon development GO:0021537 186 0.194
Mouse
regulation of stem cell differentiation GO:2000736 50 0.192
Mouse
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.192
determination of left right asymmetry in nervous system GO:0035545 1 0.190
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.190
embryonic heart tube morphogenesis GO:0003143 51 0.189
muscle cell proliferation GO:0033002 52 0.187
Mouse
regulation of gliogenesis GO:0014013 50 0.186
Mouse
epithelial to mesenchymal transition GO:0001837 47 0.183
Mouse
alpha beta t cell differentiation GO:0046632 69 0.183
mesoderm development GO:0007498 100 0.183
regulation of system process GO:0044057 200 0.183
proteoglycan metabolic process GO:0006029 38 0.182
Mouse
cellular chemical homeostasis GO:0055082 215 0.182
stem cell development GO:0048864 219 0.180
Mouse Fly
somatic diversification of immune receptors GO:0002200 53 0.179
t cell differentiation GO:0030217 174 0.178
regulation of ion transport GO:0043269 215 0.176
gastrulation GO:0007369 116 0.175
somitogenesis GO:0001756 69 0.174
respiratory tube development GO:0030323 167 0.174
Mouse
cell maturation GO:0048469 127 0.173
Fly
mesonephric tubule development GO:0072164 94 0.173
Mouse
male gamete generation GO:0048232 285 0.172
positive regulation of wnt signaling pathway GO:0030177 45 0.171
Mouse
morphogenesis of an epithelial fold GO:0060571 28 0.170
Mouse
positive regulation of mapk cascade GO:0043410 170 0.170
Mouse
regulation of interleukin 8 production GO:0032677 3 0.169
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.164
Mouse Fly
multi multicellular organism process GO:0044706 109 0.161
regulation of t cell activation GO:0050863 170 0.161
respiratory system development GO:0060541 190 0.161
Mouse Fly
immunoglobulin mediated immune response GO:0016064 69 0.160
dna recombination GO:0006310 92 0.155
action potential GO:0001508 78 0.154
organic acid transport GO:0015849 101 0.154
regulation of protein localization GO:0032880 231 0.154
positive regulation of tendon cell differentiation GO:2001051 1 0.152
cellular ketone metabolic process GO:0042180 84 0.152
mesenchyme development GO:0060485 152 0.147
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.146
lipid localization GO:0010876 126 0.146
left lung development GO:0060459 4 0.144
heart trabecula morphogenesis GO:0061384 26 0.141
specification of organ position GO:0010159 3 0.141
Mouse
carbohydrate metabolic process GO:0005975 230 0.140
glycoprotein metabolic process GO:0009100 116 0.140
Mouse
spermatogenesis GO:0007283 284 0.139
cardiac septum development GO:0003279 59 0.138
regulation of production of molecular mediator of immune response GO:0002700 65 0.138
ureteric bud morphogenesis GO:0060675 62 0.135
Mouse
macromolecule methylation GO:0043414 120 0.134
regulation of chondrocyte differentiation GO:0032330 33 0.133
Mouse
polarity specification of proximal distal axis GO:0010085 2 0.133
positive regulation of cell development GO:0010720 237 0.132
Mouse
mesonephros development GO:0001823 97 0.132
Mouse
muscle contraction GO:0006936 101 0.132
myeloid cell homeostasis GO:0002262 114 0.132
Mouse
atrioventricular valve morphogenesis GO:0003181 13 0.131
Mouse
skeletal muscle fiber development GO:0048741 58 0.131
regulation of cell migration GO:0030334 219 0.130
Mouse
cell differentiation involved in kidney development GO:0061005 33 0.130
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.130
Mouse
epiblast cell extraembryonic ectoderm cell signaling involved in anterior posterior axis specification GO:0060802 1 0.129
carbohydrate derivative biosynthetic process GO:1901137 183 0.129
epithelial cell differentiation involved in kidney development GO:0035850 23 0.129
Mouse
cellular response to organic cyclic compound GO:0071407 87 0.126
Mouse
alpha beta t cell activation GO:0046631 91 0.125
chloride transport GO:0006821 32 0.124
multicellular organismal homeostasis GO:0048871 164 0.123
acute inflammatory response GO:0002526 41 0.123
mesonephric tubule morphogenesis GO:0072171 63 0.122
Mouse
lymphocyte proliferation GO:0046651 164 0.122
response to organic cyclic compound GO:0014070 198 0.122
Mouse
nephron tubule development GO:0072080 84 0.121
Mouse
bone mineralization GO:0030282 54 0.120
Mouse
metal ion homeostasis GO:0055065 189 0.120
negative regulation of cell proliferation GO:0008285 296 0.118
Mouse
positive regulation of glial cell differentiation GO:0045687 21 0.118
Mouse
chondrocyte differentiation GO:0002062 72 0.118
Mouse
response to acid chemical GO:0001101 111 0.117
chemotaxis GO:0006935 247 0.117
Fly
floor plate morphogenesis GO:0033505 3 0.116
heart valve morphogenesis GO:0003179 21 0.115
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.115
somatotropin secreting cell differentiation GO:0060126 4 0.115
cardiocyte differentiation GO:0035051 87 0.115
Fly
stem cell proliferation GO:0072089 117 0.114
Mouse
cardiac muscle cell differentiation GO:0055007 69 0.114
positive regulation of nervous system development GO:0051962 221 0.112
Mouse
body morphogenesis GO:0010171 45 0.112
positive regulation of dna endoreduplication GO:0032877 2 0.112
mesoderm morphogenesis GO:0048332 64 0.111
Mouse
cardiac muscle tissue development GO:0048738 130 0.111
Mouse
mammary gland morphogenesis GO:0060443 54 0.111
Mouse
pituitary gland development GO:0021983 38 0.108
Mouse
regulation of bmp signaling pathway GO:0030510 60 0.108
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.108
kidney morphogenesis GO:0060993 83 0.108
Mouse
leukocyte proliferation GO:0070661 172 0.107
protein modification by small protein conjugation or removal GO:0070647 207 0.106
cellular modified amino acid metabolic process GO:0006575 63 0.106
negative regulation of cellular component organization GO:0051129 194 0.106
negative regulation of embryonic development GO:0045992 22 0.105
Mouse
b cell differentiation GO:0030183 78 0.105
metanephric collecting duct development GO:0072205 7 0.105
Mouse
regulation of kinase activity GO:0043549 249 0.104
tendon cell differentiation GO:0035990 4 0.103
Mouse
positive regulation of gliogenesis GO:0014015 27 0.103
Mouse
neuroepithelial cell differentiation GO:0060563 37 0.103
Mouse
embryonic digit morphogenesis GO:0042733 56 0.103
Mouse
maintenance of location GO:0051235 89 0.102
organic hydroxy compound metabolic process GO:1901615 203 0.101
cellular carbohydrate metabolic process GO:0044262 119 0.101
response to fibroblast growth factor GO:0071774 47 0.101
muscle cell differentiation GO:0042692 261 0.101
inflammatory response GO:0006954 244 0.100
Mouse
peptidyl amino acid modification GO:0018193 336 0.100
cellular response to growth factor stimulus GO:0071363 197 0.100
Mouse
heart morphogenesis GO:0003007 178 0.099
Mouse
regulation of striated muscle cell differentiation GO:0051153 81 0.099
macromolecule catabolic process GO:0009057 281 0.099
endocardial cushion morphogenesis GO:0003203 18 0.099
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.098
Mouse
pallium development GO:0021543 120 0.098
pancreatic a cell fate commitment GO:0003326 2 0.097
regulation of lymphocyte activation GO:0051249 240 0.096
chromatin organization GO:0006325 206 0.096
organophosphate biosynthetic process GO:0090407 122 0.096
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.095
pancreatic pp cell fate commitment GO:0003329 2 0.094
myotube cell development GO:0014904 60 0.094
transmembrane transport GO:0055085 412 0.094
tube closure GO:0060606 91 0.093
Mouse
cardiac chamber development GO:0003205 108 0.093
bone morphogenesis GO:0060349 78 0.092
Mouse
striated muscle cell development GO:0055002 125 0.091
somatic cell dna recombination GO:0016444 51 0.091
neural tube patterning GO:0021532 43 0.091
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.090
muscle tissue development GO:0060537 308 0.090
regulation of leukocyte mediated immunity GO:0002703 104 0.088
muscle system process GO:0003012 141 0.088
regulation of stem cell maintenance GO:2000036 17 0.087
dorsal ventral neural tube patterning GO:0021904 28 0.087
Mouse
neuron death GO:0070997 154 0.087
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.086
Mouse
isotype switching GO:0045190 36 0.086
cell migration involved in gastrulation GO:0042074 13 0.085
regulation of endothelial cell differentiation GO:0045601 10 0.084
Mouse
regulation of membrane potential GO:0042391 192 0.084
morphogenesis of embryonic epithelium GO:0016331 159 0.084
Mouse Fly
central nervous system neuron development GO:0021954 67 0.084
developmental growth involved in morphogenesis GO:0060560 138 0.083
Mouse
positive regulation of immune effector process GO:0002699 107 0.083
cytokine secretion GO:0050663 72 0.083
nucleocytoplasmic transport GO:0006913 139 0.082
regulation of osteoblast differentiation GO:0045667 67 0.082
Mouse
glycoprotein biosynthetic process GO:0009101 89 0.082
cellular amino acid metabolic process GO:0006520 103 0.082
nephron tubule morphogenesis GO:0072078 68 0.081
Mouse
gliogenesis GO:0042063 141 0.081
Mouse
regulation of cartilage development GO:0061035 44 0.081
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.081
organ growth GO:0035265 117 0.081
Fly
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.081
left lung morphogenesis GO:0060460 3 0.080
ubiquitin dependent protein catabolic process GO:0006511 129 0.080
amide transport GO:0042886 138 0.079
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.078
endodermal cell fate commitment GO:0001711 12 0.078
positive regulation of leukocyte proliferation GO:0070665 73 0.078
ureteric bud development GO:0001657 94 0.078
Mouse
cell differentiation in spinal cord GO:0021515 53 0.077
cell fate specification GO:0001708 72 0.077
Fly
regulation of hormone levels GO:0010817 211 0.077
blastocyst formation GO:0001825 33 0.076
segmentation GO:0035282 93 0.076
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.076
positive regulation of protein kinase activity GO:0045860 144 0.076
ion transmembrane transport GO:0034220 361 0.075
fat cell differentiation GO:0045444 160 0.075
Mouse
fertilization GO:0009566 127 0.075
inorganic anion transport GO:0015698 43 0.074
regulation of cytokine secretion GO:0050707 61 0.074
oogenesis GO:0048477 56 0.073
Fly
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.073
protein catabolic process GO:0030163 221 0.073
genetic imprinting GO:0071514 27 0.073
endocrine system development GO:0035270 98 0.072
Mouse
axon guidance GO:0007411 141 0.071
regulation of chromosome organization GO:0033044 83 0.071
somatic diversification of immunoglobulins GO:0016445 43 0.071
positive regulation of epithelial to mesenchymal transition GO:0010718 13 0.070
Mouse
cerebral cortex development GO:0021987 86 0.070
homeostasis of number of cells GO:0048872 210 0.070
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.070
regulation of organ growth GO:0046620 61 0.069
Fly
carboxylic acid transport GO:0046942 100 0.068
regulation of intracellular transport GO:0032386 159 0.068
dna modification GO:0006304 50 0.068
negative regulation of stem cell maintenance GO:1902455 4 0.068
calcium ion transport GO:0006816 159 0.067
negative regulation of secretion by cell GO:1903531 54 0.067
multicellular organismal signaling GO:0035637 91 0.067
embryonic skeletal joint morphogenesis GO:0060272 11 0.067
Mouse
regulation of establishment of protein localization GO:0070201 181 0.066
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.066
myeloid leukocyte differentiation GO:0002573 119 0.066
positive regulation of osteoblast differentiation GO:0045669 34 0.066
Mouse
oocyte construction GO:0007308 2 0.066
Fly
positive regulation of interferon gamma production GO:0032729 39 0.066
roof plate formation GO:0021509 1 0.065
negative regulation of cytokine production GO:0001818 84 0.065
endothelium development GO:0003158 45 0.065
Mouse
regulation of multicellular organismal metabolic process GO:0044246 14 0.065
kidney mesenchyme morphogenesis GO:0072131 4 0.064
hemangioblast cell differentiation GO:0060217 1 0.064
methylation GO:0032259 134 0.064
regulation of protein complex assembly GO:0043254 83 0.064
regulation of secretion GO:0051046 274 0.063
regulation of b cell mediated immunity GO:0002712 37 0.063
bundle of his development GO:0003166 4 0.063
positive regulation of ossification GO:0045778 47 0.062
Mouse
response to dietary excess GO:0002021 18 0.062
metanephric mesenchymal cell proliferation involved in metanephros development GO:0072136 2 0.062
negative regulation of secretion GO:0051048 61 0.062
mesodermal cell differentiation GO:0048333 22 0.062
Mouse
axonogenesis GO:0007409 274 0.061
organic anion transport GO:0015711 137 0.061
cellular calcium ion homeostasis GO:0006874 119 0.061
pharynx development GO:0060465 1 0.061
positive regulation of leukocyte differentiation GO:1902107 86 0.061
regulation of transferase activity GO:0051338 263 0.060
endothelial cell differentiation GO:0045446 41 0.060
Mouse
calcium ion homeostasis GO:0055074 127 0.060
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.060
protein modification by small protein conjugation GO:0032446 187 0.060
regulation of cellular component biogenesis GO:0044087 181 0.060
auditory receptor cell fate specification GO:0042667 1 0.059
cardiac ventricle development GO:0003231 83 0.059
lung development GO:0030324 164 0.059
Mouse
prostate gland development GO:0030850 48 0.059
Mouse
cell fate determination GO:0001709 32 0.059
Mouse
forebrain neuron fate commitment GO:0021877 13 0.059
ventricular cardiac muscle tissue development GO:0003229 38 0.059
morphogenesis of an epithelial bud GO:0060572 18 0.058
Mouse
tissue remodeling GO:0048771 102 0.058
regulation of receptor activity GO:0010469 41 0.058
negative regulation of cell development GO:0010721 169 0.058
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.058
renal tubule development GO:0061326 87 0.058
Mouse Fly
negative regulation of t cell proliferation GO:0042130 38 0.057
regulation of cytoplasmic transport GO:1903649 112 0.057
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.057
Mouse Fly
somite rostral caudal axis specification GO:0032525 13 0.057
divalent metal ion transport GO:0070838 172 0.056
nodal signaling pathway GO:0038092 10 0.056
embryonic axis specification GO:0000578 30 0.056
cytokine biosynthetic process GO:0042089 68 0.056
neuronal action potential GO:0019228 54 0.056
positive regulation of t cell activation GO:0050870 101 0.056
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.056
trophectodermal cellular morphogenesis GO:0001831 3 0.056
mesenchymal cell proliferation GO:0010463 44 0.055
Mouse
digestive tract development GO:0048565 190 0.055
regulation of protein kinase activity GO:0045859 232 0.055
tendon development GO:0035989 6 0.055
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.055
cd4 positive alpha beta t cell activation GO:0035710 45 0.055
membrane organization GO:0061024 245 0.055
interspecies interaction between organisms GO:0044419 83 0.055
response to nutrient levels GO:0031667 109 0.055
chromatin modification GO:0016568 187 0.055
positive regulation of neuron differentiation GO:0045666 141 0.054
Mouse
ear development GO:0043583 200 0.054
Mouse
corticotropin hormone secreting cell differentiation GO:0060128 3 0.054
Mouse
protein localization to organelle GO:0033365 185 0.054
blood circulation GO:0008015 195 0.054
negative regulation of protein metabolic process GO:0051248 282 0.054
renal filtration cell differentiation GO:0061318 10 0.053
Mouse Fly
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.053
defense response to gram negative bacterium GO:0050829 28 0.053
cardiac ventricle morphogenesis GO:0003208 50 0.053
positive regulation of cell migration GO:0030335 109 0.053
Mouse
nitrogen compound transport GO:0071705 271 0.053
lymphocyte differentiation GO:0030098 242 0.052
regulation of immunoglobulin mediated immune response GO:0002889 37 0.052
protein secretion GO:0009306 111 0.052
multi organism behavior GO:0051705 62 0.051
connective tissue development GO:0061448 179 0.051
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.051
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.051
regulation of defense response GO:0031347 233 0.051
regulation of lipid metabolic process GO:0019216 118 0.051
embryonic skeletal joint development GO:0072498 13 0.050
Mouse
cytoplasmic transport GO:0016482 234 0.050
regulation of leukocyte differentiation GO:1902105 159 0.050
nephrogenic mesenchyme development GO:0072076 3 0.050
interleukin 8 production GO:0032637 4 0.050
positive regulation of fat cell differentiation GO:0045600 32 0.049
Mouse
insulin secretion GO:0030073 89 0.049
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.049
g protein coupled receptor signaling pathway GO:0007186 243 0.049
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.049
modification dependent macromolecule catabolic process GO:0043632 133 0.049
positive regulation of lymphocyte proliferation GO:0050671 70 0.049
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.049
sclerotome development GO:0061056 4 0.049
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.048
ventricular septum development GO:0003281 42 0.048
spinal cord motor neuron differentiation GO:0021522 35 0.048
protein maturation GO:0051604 176 0.048
negative regulation of cell activation GO:0050866 111 0.048
positive regulation of cell death GO:0010942 224 0.048
notch signaling pathway GO:0007219 71 0.047
Mouse
aromatic compound catabolic process GO:0019439 286 0.047
regulation of b cell activation GO:0050864 81 0.047
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.047
Mouse
multicellular organismal metabolic process GO:0044236 28 0.047
forebrain generation of neurons GO:0021872 63 0.047
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.047
anatomical structure homeostasis GO:0060249 145 0.047
trophectodermal cell differentiation GO:0001829 21 0.046
placenta development GO:0001890 140 0.046
calcium mediated signaling GO:0019722 46 0.046
antimicrobial peptide biosynthetic process GO:0002777 2 0.046
cardiac atrium morphogenesis GO:0003209 23 0.046
regulation of chloride transport GO:2001225 2 0.046
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.046
positive regulation of cell motility GO:2000147 116 0.045
Mouse
regulation of inflammatory response GO:0050727 147 0.045
inorganic cation transmembrane transport GO:0098662 207 0.045
intracellular protein transport GO:0006886 204 0.045
dna alkylation GO:0006305 43 0.045
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.045
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.044
regulation of acute inflammatory response GO:0002673 27 0.044
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.044
branching involved in ureteric bud morphogenesis GO:0001658 56 0.044
Mouse
spinal cord development GO:0021510 81 0.043

Gdf3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.172
disease of anatomical entity DOID:7 0 0.172
cardiovascular system disease DOID:1287 0 0.172
immune system disease DOID:2914 0 0.057
hematopoietic system disease DOID:74 0 0.057