Mus musculus

0 known processes

Ap2a1

adaptor protein complex AP-2, alpha 1 subunit

(Aliases: Adtaa)

Ap2a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
endocytosis GO:0006897 168 0.572
Worm Fly
oocyte axis specification GO:0007309 2 0.480
oocyte anterior posterior axis specification GO:0007314 2 0.432
mitotic cell cycle GO:0000278 195 0.359
regulation of cell cycle GO:0051726 281 0.328
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.327
glycoprotein biosynthetic process GO:0009101 89 0.282
protein localization to membrane GO:0072657 108 0.280
regulation of protein catabolic process GO:0042176 108 0.247
response to organonitrogen compound GO:0010243 246 0.246
small gtpase mediated signal transduction GO:0007264 97 0.233
microtubule cytoskeleton organization GO:0000226 157 0.214
actin cytoskeleton organization GO:0030036 220 0.210
male gamete generation GO:0048232 285 0.197
positive regulation of protein modification process GO:0031401 299 0.191
protein catabolic process GO:0030163 221 0.190
macromolecule catabolic process GO:0009057 281 0.189
carbohydrate derivative biosynthetic process GO:1901137 183 0.187
Human
ras protein signal transduction GO:0007265 77 0.179
germ cell development GO:0007281 185 0.177
synaptic transmission GO:0007268 329 0.175
Fly
carbohydrate metabolic process GO:0005975 230 0.173
Human
vesicle organization GO:0016050 60 0.166
positive regulation of necrotic cell death GO:0010940 1 0.165
microtubule based process GO:0007017 236 0.156
memory GO:0007613 58 0.155
establishment of protein localization to membrane GO:0090150 54 0.150
organelle fission GO:0048285 170 0.149
oocyte construction GO:0007308 2 0.143
pole plasm assembly GO:0007315 2 0.135
meiotic cell cycle GO:0051321 122 0.134
cellular protein catabolic process GO:0044257 155 0.132
establishment or maintenance of cell polarity GO:0007163 86 0.130
intracellular mrna localization GO:0008298 4 0.128
single organismal cell cell adhesion GO:0016337 131 0.127
regionalization GO:0003002 337 0.124
developmental maturation GO:0021700 193 0.123
cation transport GO:0006812 399 0.116
meiotic nuclear division GO:0007126 115 0.114
mitotic cell cycle process GO:1903047 159 0.113
spermatogenesis GO:0007283 284 0.113
spermatid development GO:0007286 108 0.102
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.101
regulation of cellular ketone metabolic process GO:0010565 66 0.099
blood circulation GO:0008015 195 0.098
cell maturation GO:0048469 127 0.095
autophagy GO:0006914 45 0.094
protein localization to plasma membrane GO:0072659 57 0.092
regulation of cell cycle process GO:0010564 160 0.091
apoptotic signaling pathway GO:0097190 306 0.091
rho protein signal transduction GO:0007266 32 0.091
regulation of secretion by cell GO:1903530 249 0.089
glycoprotein metabolic process GO:0009100 116 0.089
oocyte differentiation GO:0009994 35 0.089
regulation of cellular component biogenesis GO:0044087 181 0.089
positive regulation of organelle organization GO:0010638 128 0.088
glycerophospholipid metabolic process GO:0006650 71 0.086
lipid modification GO:0030258 65 0.085
protein modification by small protein conjugation GO:0032446 187 0.084
regulation of mitotic cell cycle GO:0007346 126 0.084
membrane organization GO:0061024 245 0.083
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.083
response to peptide hormone GO:0043434 127 0.083
cellular ion homeostasis GO:0006873 165 0.080
maternal determination of anterior posterior axis embryo GO:0008358 2 0.080
female gamete generation GO:0007292 74 0.079
positive regulation of protein phosphorylation GO:0001934 242 0.078
spermatid differentiation GO:0048515 115 0.078
protein modification by small protein conjugation or removal GO:0070647 207 0.078
oocyte development GO:0048599 33 0.078
synaptic vesicle localization GO:0097479 59 0.077
Fly
purine containing compound catabolic process GO:0072523 213 0.076
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.076
regulation of vesicle mediated transport GO:0060627 139 0.075
Fly
coagulation GO:0050817 78 0.075
cellular response to organonitrogen compound GO:0071417 145 0.074
regulation of protein stability GO:0031647 52 0.074
nucleobase containing small molecule metabolic process GO:0055086 352 0.074
transmembrane transport GO:0055085 412 0.074
cellular ketone metabolic process GO:0042180 84 0.072
endomembrane system organization GO:0010256 147 0.072
glycosyl compound catabolic process GO:1901658 206 0.071
cellular macromolecule catabolic process GO:0044265 206 0.071
clathrin coat assembly GO:0048268 2 0.071
peptidyl amino acid modification GO:0018193 336 0.069
cell type specific apoptotic process GO:0097285 268 0.067
compound eye development GO:0048749 1 0.064
regulation of cellular catabolic process GO:0031329 242 0.062
maintenance of location GO:0051235 89 0.062
protein processing GO:0016485 163 0.062
oogenesis GO:0048477 56 0.061
dephosphorylation GO:0016311 129 0.061
phosphatidylinositol phosphorylation GO:0046854 23 0.061
ion transmembrane transport GO:0034220 361 0.060
cellular response to nutrient levels GO:0031669 64 0.060
regulation of exocytosis GO:0017157 61 0.059
circulatory system process GO:0003013 197 0.058
plasma membrane organization GO:0007009 90 0.058
homeostasis of number of cells GO:0048872 210 0.057
cellular response to peptide GO:1901653 92 0.057
establishment of organelle localization GO:0051656 122 0.057
Fly
glycerolipid biosynthetic process GO:0045017 50 0.056
purine nucleoside metabolic process GO:0042278 241 0.056
purine nucleotide metabolic process GO:0006163 302 0.055
single organism cell adhesion GO:0098602 156 0.055
microtubule based movement GO:0007018 84 0.055
cellular response to dna damage stimulus GO:0006974 207 0.054
lipid biosynthetic process GO:0008610 179 0.053
nuclear division GO:0000280 158 0.053
positive regulation of dendrite development GO:1900006 21 0.053
negative regulation of protein metabolic process GO:0051248 282 0.052
t cell activation GO:0042110 289 0.052
lymphocyte differentiation GO:0030098 242 0.051
regulation of protein localization GO:0032880 231 0.051
protein localization to organelle GO:0033365 185 0.050
protein glycosylation GO:0006486 55 0.050
synaptic vesicle transport GO:0048489 57 0.050
Fly
phospholipid metabolic process GO:0006644 87 0.049
regulation of calcium ion transport GO:0051924 69 0.049
cilium morphogenesis GO:0060271 102 0.048
t cell differentiation GO:0030217 174 0.048
regulation of endocytosis GO:0030100 69 0.048
Fly
cell substrate adhesion GO:0031589 130 0.048
heterocycle catabolic process GO:0046700 280 0.047
glycosylation GO:0070085 62 0.047
negative regulation of neuron death GO:1901215 98 0.047
peptidyl serine modification GO:0018209 83 0.046
purine containing compound metabolic process GO:0072521 311 0.046
segmentation GO:0035282 93 0.045
cellular nitrogen compound catabolic process GO:0044270 280 0.045
immune effector process GO:0002252 321 0.045
axonogenesis GO:0007409 274 0.045
establishment of protein localization to plasma membrane GO:0090002 34 0.044
proteasomal protein catabolic process GO:0010498 98 0.044
regulation of embryonic development GO:0045995 71 0.044
nucleoside metabolic process GO:0009116 246 0.043
glycerolipid metabolic process GO:0046486 122 0.043
ubiquitin dependent protein catabolic process GO:0006511 129 0.043
positive regulation of neuron projection development GO:0010976 79 0.042
posttranscriptional regulation of gene expression GO:0010608 155 0.042
regulation of apoptotic signaling pathway GO:2001233 197 0.042
rhythmic process GO:0048511 174 0.042
wound healing GO:0042060 157 0.042
cellular chemical homeostasis GO:0055082 215 0.042
learning or memory GO:0007611 148 0.042
regulation of cardioblast differentiation GO:0051890 3 0.042
phosphatidylinositol metabolic process GO:0046488 45 0.041
cell cell junction organization GO:0045216 72 0.041
nucleotide metabolic process GO:0009117 332 0.041
cellular response to peptide hormone stimulus GO:0071375 92 0.040
muscle system process GO:0003012 141 0.040
phosphatidic acid biosynthetic process GO:0006654 2 0.040
aromatic compound catabolic process GO:0019439 286 0.040
gtp catabolic process GO:0006184 143 0.040
regulation of cardiac cell fate specification GO:2000043 1 0.040
lipid phosphorylation GO:0046834 25 0.039
ribonucleoside metabolic process GO:0009119 245 0.039
cytoskeletal anchoring at plasma membrane GO:0007016 2 0.039
peptidyl serine phosphorylation GO:0018105 74 0.038
negative regulation of triglyceride biosynthetic process GO:0010868 2 0.038
regulation of cell size GO:0008361 72 0.038
intracellular protein transport GO:0006886 204 0.038
cell adhesion GO:0007155 329 0.038
response to peptide GO:1901652 136 0.038
nucleoside triphosphate catabolic process GO:0009143 205 0.037
regulation of cellular component size GO:0032535 121 0.037
divalent metal ion transport GO:0070838 172 0.037
positive regulation of cellular component biogenesis GO:0044089 94 0.037
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.037
inorganic cation transmembrane transport GO:0098662 207 0.037
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.036
acylglycerol metabolic process GO:0006639 55 0.036
cell matrix adhesion GO:0007160 68 0.036
purine nucleoside triphosphate catabolic process GO:0009146 203 0.036
development of primary sexual characteristics GO:0045137 143 0.036
positive regulation of cell projection organization GO:0031346 95 0.036
positive regulation of gtpase activity GO:0043547 85 0.035
regulation of establishment of protein localization GO:0070201 181 0.035
regulation of cell motility GO:2000145 236 0.035
hemostasis GO:0007599 78 0.035
regulation of leukocyte differentiation GO:1902105 159 0.035
negative regulation of apoptotic signaling pathway GO:2001234 104 0.035
ribonucleoside triphosphate catabolic process GO:0009203 199 0.035
ribonucleoside catabolic process GO:0042454 206 0.035
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.034
membrane tubulation GO:0097320 4 0.033
primitive erythrocyte differentiation GO:0060319 3 0.033
myotube differentiation GO:0014902 105 0.033
response to insulin GO:0032868 100 0.033
purine nucleoside catabolic process GO:0006152 205 0.033
positive regulation of transferase activity GO:0051347 167 0.033
regulation of anatomical structure size GO:0090066 178 0.033
oxidation reduction process GO:0055114 342 0.032
phagocytosis GO:0006909 66 0.032
regulation of cell projection organization GO:0031344 206 0.032
stem cell differentiation GO:0048863 268 0.032
monosaccharide metabolic process GO:0005996 106 0.032
regulation of neuron differentiation GO:0045664 281 0.031
receptor mediated endocytosis GO:0006898 51 0.031
Worm
guanosine containing compound metabolic process GO:1901068 144 0.031
thermosensory behavior GO:0040040 1 0.031
nucleoside triphosphate metabolic process GO:0009141 230 0.031
regulation of transferase activity GO:0051338 263 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.030
regulation of body fluid levels GO:0050878 162 0.030
cellular lipid metabolic process GO:0044255 323 0.030
regulation of cellular protein catabolic process GO:1903362 61 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
gtp metabolic process GO:0046039 144 0.029
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.029
directional locomotion GO:0033058 3 0.029
cellular response to hormone stimulus GO:0032870 150 0.029
protein o linked glycosylation GO:0006493 16 0.029
response to radiation GO:0009314 165 0.029
neurotransmitter secretion GO:0007269 62 0.029
positive regulation of proteolysis GO:0045862 85 0.028
mitotic nuclear division GO:0007067 48 0.028
macromolecule glycosylation GO:0043413 55 0.028
retrograde transport endosome to golgi GO:0042147 2 0.028
positive regulation of mapk cascade GO:0043410 170 0.028
regulation of protein serine threonine kinase activity GO:0071900 157 0.028
regulation of proteolysis GO:0030162 164 0.028
organelle assembly GO:0070925 177 0.028
translation GO:0006412 93 0.028
response to nutrient levels GO:0031667 109 0.028
locomotory behavior GO:0007626 195 0.027
positive regulation of cell motility GO:2000147 116 0.027
neuron apoptotic process GO:0051402 142 0.027
organonitrogen compound catabolic process GO:1901565 264 0.027
positive regulation of nucleotide metabolic process GO:0045981 114 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
cell junction organization GO:0034330 77 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
cellular response to insulin stimulus GO:0032869 78 0.026
response to light stimulus GO:0009416 135 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
nitrogen compound transport GO:0071705 271 0.026
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
cognition GO:0050890 149 0.026
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.026
regulation of cytoplasmic translation GO:2000765 4 0.026
cytoplasmic transport GO:0016482 234 0.026
response to lipopolysaccharide GO:0032496 128 0.026
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.025
striated muscle tissue development GO:0014706 293 0.025
positive regulation of mitotic metaphase anaphase transition GO:0045842 2 0.025
establishment of protein localization to organelle GO:0072594 118 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
organophosphate catabolic process GO:0046434 232 0.025
transmission of nerve impulse GO:0019226 76 0.025
negative regulation of protein modification process GO:0031400 163 0.024
cellular amino acid metabolic process GO:0006520 103 0.024
organelle localization GO:0051640 179 0.024
Fly
epithelial tube morphogenesis GO:0060562 303 0.024
modification dependent macromolecule catabolic process GO:0043632 133 0.024
glucose homeostasis GO:0042593 128 0.024
divalent inorganic cation transport GO:0072511 178 0.024
olfactory learning GO:0008355 2 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
adult behavior GO:0030534 135 0.024
cellular response to lipopolysaccharide GO:0071222 77 0.023
calcium ion transport GO:0006816 159 0.023
insulin receptor signaling pathway GO:0008286 49 0.023
chromosome segregation GO:0007059 48 0.023
positive regulation of endocytosis GO:0045807 42 0.023
Fly
myeloid cell apoptotic process GO:0033028 22 0.023
positive regulation of protein catabolic process GO:0045732 60 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
neurotransmitter transport GO:0006836 76 0.023
synaptic vesicle recycling GO:0036465 19 0.023
Fly
cation transmembrane transport GO:0098655 266 0.023
regulation of neuron projection development GO:0010975 169 0.022
negative regulation of phosphorylation GO:0042326 166 0.022
regulation of cytokine production GO:0001817 266 0.022
cytoskeleton dependent intracellular transport GO:0030705 50 0.022
establishment of synaptic vesicle localization GO:0097480 57 0.022
Fly
positive regulation of gtp catabolic process GO:0033126 85 0.022
regulation of ion transport GO:0043269 215 0.022
regulation of stress activated mapk cascade GO:0032872 69 0.022
nuclear import GO:0051170 95 0.022
negative regulation of lipid metabolic process GO:0045833 30 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
organic anion transport GO:0015711 137 0.022
inorganic ion transmembrane transport GO:0098660 234 0.021
respiratory system development GO:0060541 190 0.021
divalent inorganic cation homeostasis GO:0072507 138 0.021
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.021
epithelial cell proliferation GO:0050673 174 0.021
germinal center formation GO:0002467 16 0.021
negative regulation of triglyceride metabolic process GO:0090209 4 0.021
negative regulation of protein phosphorylation GO:0001933 126 0.021
regulation of fat cell differentiation GO:0045598 81 0.021
circadian rhythm GO:0007623 114 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
regulation of proteasomal protein catabolic process GO:0061136 46 0.021
positive regulation of cellular protein catabolic process GO:1903364 34 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
carbohydrate transport GO:0008643 62 0.020
cellular amine metabolic process GO:0044106 44 0.020
regulation of lymphocyte differentiation GO:0045619 107 0.020
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
regulation of cell activation GO:0050865 289 0.020
guanosine containing compound catabolic process GO:1901069 144 0.020
sequestering of calcium ion GO:0051208 18 0.020
positive regulation of nervous system development GO:0051962 221 0.020
lymphocyte apoptotic process GO:0070227 54 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
muscle tissue development GO:0060537 308 0.020
glucose metabolic process GO:0006006 92 0.020
homotypic cell cell adhesion GO:0034109 28 0.019
cell junction maintenance GO:0034331 4 0.019
positive regulation of cell development GO:0010720 237 0.019
mapk cascade GO:0000165 281 0.019
cytokine production GO:0001816 319 0.019
platelet activation GO:0030168 40 0.019
thymocyte migration GO:0072679 2 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
axon cargo transport GO:0008088 33 0.019
cell fate commitment GO:0045165 210 0.019
ovarian follicle development GO:0001541 40 0.019
regulation of intracellular transport GO:0032386 159 0.019
regulation of protein kinase activity GO:0045859 232 0.019
negative regulation of neuron apoptotic process GO:0043524 92 0.019
sensory perception GO:0007600 245 0.019
adherens junction maintenance GO:0034334 1 0.019
rna localization GO:0006403 23 0.018
protein oligomerization GO:0051259 67 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.018
regulation of map kinase activity GO:0043405 120 0.018
regulation of secretion GO:0051046 274 0.018
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 6 0.018
regulation of cell substrate adhesion GO:0010810 73 0.018
myeloid cell differentiation GO:0030099 233 0.018
meiotic cell cycle process GO:1903046 77 0.018
regulation of membrane potential GO:0042391 192 0.018
dna metabolic process GO:0006259 303 0.018
fertilization GO:0009566 127 0.018
positive regulation of cellular catabolic process GO:0031331 148 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.018
establishment of protein localization to vacuole GO:0072666 4 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
fucose metabolic process GO:0006004 1 0.018
male sex differentiation GO:0046661 109 0.017
regulation of lipid biosynthetic process GO:0046890 54 0.017
regulation of protein binding GO:0043393 60 0.017
jak stat cascade GO:0007259 42 0.017
myeloid leukocyte migration GO:0097529 57 0.017
negative regulation of synapse assembly GO:0051964 3 0.017
regulation of translation GO:0006417 71 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
multicellular organism growth GO:0035264 161 0.017
learning GO:0007612 98 0.017
response to extracellular stimulus GO:0009991 127 0.017
nuclear transport GO:0051169 139 0.017
regulation of protein maturation GO:1903317 96 0.017
social behavior GO:0035176 21 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.017
multicellular organismal signaling GO:0035637 91 0.017
visual learning GO:0008542 44 0.017
microtubule based transport GO:0010970 50 0.017
positive regulation of cell cycle process GO:0090068 61 0.016
cellular response to starvation GO:0009267 57 0.016
positive regulation of cell cycle GO:0045787 92 0.016
cellularization GO:0007349 1 0.016
lung development GO:0030324 164 0.016
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
genitalia development GO:0048806 37 0.016
forebrain development GO:0030900 302 0.016
regulation of circadian rhythm GO:0042752 58 0.016
regulation of metal ion transport GO:0010959 106 0.016
regulation of homeostatic process GO:0032844 182 0.016
synaptic vesicle endocytosis GO:0048488 19 0.016
Fly
t cell differentiation in thymus GO:0033077 77 0.016
regulation of defense response GO:0031347 233 0.016
b cell activation GO:0042113 161 0.016
nucleoside phosphate biosynthetic process GO:1901293 79 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
cell division GO:0051301 120 0.016
response to organic cyclic compound GO:0014070 198 0.016
tumor necrosis factor ligand superfamily member 11 production GO:0072535 1 0.016
ameboidal type cell migration GO:0001667 128 0.016
leukocyte apoptotic process GO:0071887 71 0.015
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.015
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.015
phosphatidic acid metabolic process GO:0046473 2 0.015
protein ubiquitination GO:0016567 171 0.015
positive regulation of calcium ion transport GO:0051928 27 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
regulation of eosinophil migration GO:2000416 2 0.015
smoothened signaling pathway GO:0007224 105 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.015
dendrite development GO:0016358 115 0.015
detection of external stimulus GO:0009581 61 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.015
regulation of thymocyte migration GO:2000410 2 0.015
negative regulation of lyase activity GO:0051350 1 0.015
retina morphogenesis in camera type eye GO:0060042 45 0.015
positive regulation of thymocyte migration GO:2000412 2 0.015
regulation of intracellular protein transport GO:0033157 82 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.015
regulation of meiotic cell cycle GO:0051445 34 0.015
regulation of mapk cascade GO:0043408 248 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
macroautophagy GO:0016236 21 0.015
regulation of protein ubiquitination GO:0031396 52 0.015
protein localization to vacuole GO:0072665 4 0.014
regulation of cellular amine metabolic process GO:0033238 20 0.014
maintenance of location in cell GO:0051651 24 0.014
chemotaxis GO:0006935 247 0.014
eosinophil migration GO:0072677 3 0.014
cell growth GO:0016049 130 0.014
positive regulation of kinase activity GO:0033674 155 0.014
cellular protein complex assembly GO:0043623 116 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
cellular homeostasis GO:0019725 240 0.014
inflammatory response GO:0006954 244 0.014
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.014
vesicle localization GO:0051648 86 0.014
Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
protein autophosphorylation GO:0046777 61 0.014
sensory system development GO:0048880 3 0.014
triglyceride biosynthetic process GO:0019432 17 0.014
male gonad development GO:0008584 88 0.014
granulocyte migration GO:0097530 43 0.014
detection of mechanical stimulus GO:0050982 27 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
lipid homeostasis GO:0055088 63 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
cellular response to amino acid stimulus GO:0071230 29 0.014
regulation of fibroblast proliferation GO:0048145 34 0.014
placenta development GO:0001890 140 0.014
gonad development GO:0008406 141 0.014
regulation of neurotransmitter levels GO:0001505 87 0.014
striated muscle contraction GO:0006941 45 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
fibronectin dependent thymocyte migration GO:0072681 1 0.013
regulation of cell shape GO:0008360 39 0.013
regulation of leukocyte mediated immunity GO:0002703 104 0.013
sodium ion transmembrane transport GO:0035725 49 0.013
conditioned taste aversion GO:0001661 4 0.013
stress activated protein kinase signaling cascade GO:0031098 81 0.013
positive regulation of meiotic cell cycle GO:0051446 15 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
signal transduction by p53 class mediator GO:0072331 51 0.013
response to starvation GO:0042594 65 0.013
necrotic cell death GO:0070265 30 0.013
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.013
regulation of system process GO:0044057 200 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
positive regulation of ras gtpase activity GO:0032320 65 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
negative regulation of cell cycle GO:0045786 123 0.013
regulation of gtp catabolic process GO:0033124 113 0.013
ventricular cardiac muscle cell action potential GO:0086005 4 0.013
protein maturation GO:0051604 176 0.013
macromolecule methylation GO:0043414 120 0.013
peripheral nervous system development GO:0007422 53 0.013
negative regulation of gluconeogenesis GO:0045721 9 0.013
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.013
tissue homeostasis GO:0001894 115 0.013
cell cell junction assembly GO:0007043 27 0.013
proteoglycan metabolic process GO:0006029 38 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
regulation of ossification GO:0030278 112 0.012
leukocyte differentiation GO:0002521 342 0.012
regulation of reproductive process GO:2000241 66 0.012
regulation of notch signaling pathway GO:0008593 35 0.012
positive regulation of response to wounding GO:1903036 66 0.012
muscle contraction GO:0006936 101 0.012
negative regulation of ras protein signal transduction GO:0046580 18 0.012
response to parathyroid hormone GO:0071107 3 0.012
female meiotic division GO:0007143 21 0.012
regulation of carbohydrate metabolic process GO:0006109 75 0.012
Human
modification dependent protein catabolic process GO:0019941 133 0.012
regulation of smoothened signaling pathway GO:0008589 58 0.012
positive regulation of interleukin 13 production GO:0032736 4 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
regulation of nuclear division GO:0051783 56 0.012
bone development GO:0060348 120 0.012
regulation of heart contraction GO:0008016 77 0.012

Ap2a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.209
nervous system disease DOID:863 0 0.209
neuromuscular disease DOID:440 0 0.035
neuropathy DOID:870 0 0.035
epilepsy syndrome DOID:1826 0 0.020
central nervous system disease DOID:331 0 0.020
brain disease DOID:936 0 0.020
electroclinical syndrome DOID:0050701 0 0.020
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.015