Mus musculus

51 known processes

Clec4e

C-type lectin domain family 4, member e

(Aliases: Clecsf9,Mincle,C86253)

Clec4e biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
detection of fungus GO:0016046 2 0.999
Mouse
detection of yeast GO:0001879 2 0.981
Mouse
detection of other organism GO:0098543 8 0.862
Mouse
defense response to other organism GO:0098542 197 0.849
Mouse
neutrophil migration GO:1990266 37 0.771
positive regulation of cytokine biosynthetic process GO:0042108 40 0.768
Mouse
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.724
i kappab kinase nf kappab signaling GO:0007249 85 0.720
Mouse
cytokine production GO:0001816 319 0.710
positive regulation of defense response GO:0031349 124 0.697
positive regulation of cytokine production GO:0001819 174 0.696
keratinocyte migration GO:0051546 3 0.691
regulation of cytokine biosynthetic process GO:0042035 59 0.635
Mouse
inflammatory response GO:0006954 244 0.630
regulation of inflammatory response GO:0050727 147 0.604
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.599
chemotaxis GO:0006935 247 0.598
activation of innate immune response GO:0002218 56 0.581
positive regulation of innate immune response GO:0045089 80 0.527
regulation of cell activation GO:0050865 289 0.513
Mouse
negative regulation of lymphocyte activation GO:0051250 91 0.513
Mouse
regulation of cytokine production GO:0001817 266 0.510
positive regulation of macrophage chemotaxis GO:0010759 5 0.508
regulation of chemokine production GO:0032642 30 0.500
detection of external biotic stimulus GO:0098581 9 0.497
Mouse
cation homeostasis GO:0055080 212 0.482
Mouse
regulation of defense response GO:0031347 233 0.463
detection of biotic stimulus GO:0009595 10 0.455
Mouse
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.447
leukocyte proliferation GO:0070661 172 0.442
Mouse
regulation of ion transport GO:0043269 215 0.430
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.421
pattern recognition receptor signaling pathway GO:0002221 47 0.418
release of sequestered calcium ion into cytosol GO:0051209 42 0.416
Mouse
negative regulation of t cell proliferation GO:0042130 38 0.412
Mouse
cytokine biosynthetic process GO:0042089 68 0.404
Mouse
positive regulation of homeostatic process GO:0032846 64 0.402
Mouse
cellular response to biotic stimulus GO:0071216 92 0.397
regulation of homeostatic process GO:0032844 182 0.396
Mouse
response to molecule of bacterial origin GO:0002237 143 0.394
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.387
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.381
Mouse
regulation of ion homeostasis GO:2000021 64 0.379
Mouse
regulation of cytokine secretion GO:0050707 61 0.375
regulation of phagocytosis GO:0050764 33 0.373
Mouse
t cell activation GO:0042110 289 0.365
Mouse
second messenger mediated signaling GO:0019932 73 0.365
regulation of t cell proliferation GO:0042129 92 0.364
Mouse
lymphocyte proliferation GO:0046651 164 0.357
Mouse
regulation of protein transport GO:0051223 163 0.351
positive regulation of intracellular transport GO:0032388 70 0.346
Mouse
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.346
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.343
t cell proliferation GO:0042098 120 0.342
Mouse
cytokine secretion GO:0050663 72 0.335
regulation of response to wounding GO:1903034 189 0.334
negative regulation of immune system process GO:0002683 209 0.332
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.331
cellular response to cytokine stimulus GO:0071345 189 0.327
regulation of innate immune response GO:0045088 91 0.309
regulation of lymphocyte activation GO:0051249 240 0.308
Mouse
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.299
Mouse
cytokine metabolic process GO:0042107 71 0.295
Mouse
positive regulation of protein transport GO:0051222 93 0.284
positive regulation of inflammatory response GO:0050729 47 0.271
positive regulation of neutrophil chemotaxis GO:0090023 12 0.271
tumor necrosis factor production GO:0032640 50 0.267
Mouse
phagocytosis GO:0006909 66 0.266
Mouse
immune response activating signal transduction GO:0002757 116 0.264
regulation of secretion GO:0051046 274 0.263
negative regulation of t cell activation GO:0050868 65 0.261
Mouse
positive regulation of immune effector process GO:0002699 107 0.260
Mouse
regulation of endocytosis GO:0030100 69 0.256
Mouse
innate immune response activating signal transduction GO:0002758 50 0.255
neutrophil chemotaxis GO:0030593 36 0.249
cellular response to molecule of bacterial origin GO:0071219 83 0.247
positive regulation of calcium ion transport GO:0051928 27 0.244
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.244
Mouse
sequestering of calcium ion GO:0051208 18 0.243
regulation of leukocyte proliferation GO:0070663 121 0.243
Mouse
myeloid leukocyte migration GO:0097529 57 0.239
t cell mediated immunity GO:0002456 50 0.238
Mouse
regulation of intracellular transport GO:0032386 159 0.233
Mouse
myeloid leukocyte mediated immunity GO:0002444 42 0.230
immune response regulating signaling pathway GO:0002764 125 0.228
positive regulation of leukocyte differentiation GO:1902107 86 0.226
negative regulation of adaptive immune response GO:0002820 25 0.225
Mouse
cellular ion homeostasis GO:0006873 165 0.223
Mouse
divalent inorganic cation transport GO:0072511 178 0.220
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.220
positive regulation of cytoplasmic transport GO:1903651 40 0.219
Mouse
cellular chemical homeostasis GO:0055082 215 0.219
Mouse
negative regulation of cell proliferation GO:0008285 296 0.215
Mouse
regulation of cellular response to stress GO:0080135 159 0.212
myeloid cell differentiation GO:0030099 233 0.209
defense response to virus GO:0051607 68 0.207
defense response to gram positive bacterium GO:0050830 50 0.205
cation transport GO:0006812 399 0.200
Mouse
regulation of t cell activation GO:0050863 170 0.199
Mouse
positive regulation of endocytosis GO:0045807 42 0.197
Mouse
negative regulation of leukocyte mediated immunity GO:0002704 29 0.196
Mouse
regulation of establishment of protein localization GO:0070201 181 0.196
positive regulation of response to wounding GO:1903036 66 0.195
cellular divalent inorganic cation homeostasis GO:0072503 127 0.194
Mouse
immune effector process GO:0002252 321 0.193
Mouse
negative regulation of chemokine production GO:0032682 4 0.191
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.188
regulation of immunoglobulin mediated immune response GO:0002889 37 0.188
Mouse
defense response to bacterium GO:0042742 119 0.188
Mouse
neutrophil mediated cytotoxicity GO:0070942 8 0.187
positive regulation of cell motility GO:2000147 116 0.184
antibacterial peptide secretion GO:0002779 1 0.182
endocytosis GO:0006897 168 0.182
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.181
Mouse
cytosolic calcium ion homeostasis GO:0051480 70 0.180
Mouse
negative regulation of lymphocyte proliferation GO:0050672 45 0.178
Mouse
regulation of tumor necrosis factor production GO:0032680 49 0.176
Mouse
cellular metal ion homeostasis GO:0006875 151 0.175
Mouse
alpha beta t cell activation GO:0046631 91 0.175
Mouse
detection of stimulus GO:0051606 84 0.175
Mouse
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.174
t helper cell differentiation GO:0042093 28 0.174
neutrophil mediated immunity GO:0002446 19 0.172
regulation of cell motility GO:2000145 236 0.169
regulation of b cell mediated immunity GO:0002712 37 0.167
Mouse
positive regulation of protein secretion GO:0050714 52 0.167
cellular calcium ion homeostasis GO:0006874 119 0.166
Mouse
positive regulation of leukocyte mediated immunity GO:0002705 70 0.166
Mouse
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.165
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.164
regulation of t cell mediated immunity GO:0002709 34 0.164
Mouse
disruption by host of symbiont cells GO:0051852 11 0.160
lymphocyte mediated immunity GO:0002449 139 0.157
Mouse
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.154
adaptive immune response GO:0002250 155 0.152
Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.152
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.150
antibacterial peptide biosynthetic process GO:0002780 2 0.149
defense response to fungus GO:0050832 12 0.148
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.148
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.143
Mouse
response to lipopolysaccharide GO:0032496 128 0.142
divalent metal ion transport GO:0070838 172 0.142
Mouse
regulation of protein localization GO:0032880 231 0.140
regulation of vesicle mediated transport GO:0060627 139 0.138
Mouse
amide transport GO:0042886 138 0.137
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.137
Mouse
response to yeast GO:0001878 6 0.134
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.133
positive regulation of monocyte chemotaxis GO:0090026 2 0.132
jnk cascade GO:0007254 72 0.131
regulation of chemokine secretion GO:0090196 4 0.130
cytosolic calcium ion transport GO:0060401 48 0.130
Mouse
negative regulation of homeostatic process GO:0032845 71 0.130
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.130
regulation of neutrophil migration GO:1902622 14 0.128
activation of immune response GO:0002253 138 0.127
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.126
positive regulation of chemokine production GO:0032722 22 0.125
regulation of adiponectin secretion GO:0070163 2 0.122
cell chemotaxis GO:0060326 81 0.121
positive regulation of secretion by cell GO:1903532 114 0.120
positive regulation of secretion GO:0051047 130 0.120
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.120
Mouse
phagocytosis recognition GO:0006910 12 0.119
Mouse
negative regulation of immune effector process GO:0002698 55 0.117
Mouse
interferon gamma production GO:0032609 67 0.117
cellular response to molecule of fungal origin GO:0071226 2 0.115
positive regulation of lymphocyte proliferation GO:0050671 70 0.115
positive regulation of chemotaxis GO:0050921 38 0.115
positive regulation of hematopoietic stem cell proliferation GO:1902035 2 0.114
antimicrobial peptide production GO:0002775 2 0.113
killing of cells of other organism GO:0031640 13 0.112
natural killer cell activation GO:0030101 44 0.111
leukocyte differentiation GO:0002521 342 0.111
myeloid leukocyte differentiation GO:0002573 119 0.111
leukocyte mediated cytotoxicity GO:0001909 62 0.110
maintenance of location GO:0051235 89 0.110
negative regulation of cytokine production GO:0001818 84 0.110
positive regulation of granulocyte chemotaxis GO:0071624 12 0.109
wound healing GO:0042060 157 0.108
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.107
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.107
cell activation involved in immune response GO:0002263 126 0.107
positive regulation of apoptotic process GO:0043065 217 0.106
negative regulation of t cell mediated immunity GO:0002710 9 0.105
Mouse
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.104
positive regulation of interferon gamma production GO:0032729 39 0.103
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.102
fat cell differentiation GO:0045444 160 0.102
antimicrobial peptide biosynthetic process GO:0002777 2 0.101
immunoglobulin mediated immune response GO:0016064 69 0.098
Mouse
cellular homeostasis GO:0019725 240 0.098
Mouse
positive regulation of calcium ion transport into cytosol GO:0010524 9 0.097
Mouse
organic anion transport GO:0015711 137 0.096
nitrogen compound transport GO:0071705 271 0.095
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.095
g protein coupled receptor signaling pathway GO:0007186 243 0.095
inflammatory response to wounding GO:0090594 4 0.094
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.093
regulation of leukocyte mediated immunity GO:0002703 104 0.092
Mouse
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 10 0.089
Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.088
regulation of cytoplasmic transport GO:1903649 112 0.087
Mouse
peptide metabolic process GO:0006518 46 0.087
peptide transport GO:0015833 133 0.087
blood vessel morphogenesis GO:0048514 285 0.086
cytokine mediated signaling pathway GO:0019221 115 0.086
neutrophil mediated killing of bacterium GO:0070944 6 0.086
protein secretion GO:0009306 111 0.085
ossification GO:0001503 216 0.085
macrophage chemotaxis GO:0048246 14 0.084
interleukin 18 mediated signaling pathway GO:0035655 2 0.084
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.082
leukocyte mediated immunity GO:0002443 174 0.082
Mouse
regulation of multi organism process GO:0043900 111 0.081
rho protein signal transduction GO:0007266 32 0.081
positive regulation of cell activation GO:0050867 158 0.080
positive regulation of chemokine secretion GO:0090197 4 0.080
regulation of secretion by cell GO:1903530 249 0.080
nucleoside phosphate metabolic process GO:0006753 338 0.080
anion transport GO:0006820 177 0.080
antibacterial peptide production GO:0002778 2 0.079
regulation of interleukin 6 production GO:0032675 55 0.079
positive regulation of leukocyte proliferation GO:0070665 73 0.078
innate immune response GO:0045087 157 0.078
Mouse
t cell differentiation involved in immune response GO:0002292 30 0.078
regulation of rho protein signal transduction GO:0035023 71 0.078
activation of mapk activity involved in innate immune response GO:0035419 2 0.077
leukocyte chemotaxis GO:0030595 69 0.076
positive regulation of tumor necrosis factor production GO:0032760 30 0.076
Mouse
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.076
regulation of neutrophil mediated killing of bacterium GO:0070950 1 0.076
regulation of thymocyte migration GO:2000410 2 0.075
cellular response to lipid GO:0071396 145 0.075
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.075
Mouse
positive regulation of chemokine biosynthetic process GO:0045080 6 0.075
stress activated protein kinase signaling cascade GO:0031098 81 0.074
regulation of defense response to bacterium GO:1900424 3 0.073
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.073
response to organonitrogen compound GO:0010243 246 0.073
positive regulation of cytokine secretion GO:0050715 41 0.072
regulation of chemokine biosynthetic process GO:0045073 8 0.071
cytokine production involved in immune response GO:0002367 34 0.070
regulation of cellular response to oxidative stress GO:1900407 19 0.070
toll like receptor signaling pathway GO:0002224 38 0.070
alpha beta t cell activation involved in immune response GO:0002287 31 0.070
homeostasis of number of cells GO:0048872 210 0.070
negative regulation of serotonin secretion GO:0014063 2 0.070
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.070
multicellular organismal homeostasis GO:0048871 164 0.070
regulation of metal ion transport GO:0010959 106 0.069
Mouse
regulation of interferon gamma production GO:0032649 57 0.069
ameboidal type cell migration GO:0001667 128 0.068
regulation of vascular endothelial growth factor production GO:0010574 13 0.068
regulation of mapk cascade GO:0043408 248 0.068
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.068
positive regulation of b cell mediated immunity GO:0002714 26 0.067
Mouse
ribonucleotide metabolic process GO:0009259 291 0.067
regulation of adaptive immune response GO:0002819 90 0.067
Mouse
interleukin 11 mediated signaling pathway GO:0038154 2 0.066
apoptotic signaling pathway GO:0097190 306 0.065
mononuclear cell migration GO:0071674 8 0.065
negative regulation of synapse assembly GO:0051964 3 0.065
tumor necrosis factor biosynthetic process GO:0042533 10 0.064
Mouse
positive regulation of t cell activation GO:0050870 101 0.063
regulation of stress activated mapk cascade GO:0032872 69 0.062
macromolecule catabolic process GO:0009057 281 0.062
response to molecule of fungal origin GO:0002238 4 0.062
positive regulation vascular endothelial growth factor production GO:0010575 10 0.061
positive regulation of type 2 immune response GO:0002830 9 0.061
regulation of map kinase activity GO:0043405 120 0.061
chemokine production GO:0032602 34 0.061
purine containing compound metabolic process GO:0072521 311 0.060
regulation of calcium ion transport GO:0051924 69 0.060
Mouse
metal ion homeostasis GO:0055065 189 0.060
Mouse
single organism cell adhesion GO:0098602 156 0.060
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.060
positive regulation of lymphocyte differentiation GO:0045621 61 0.059
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.058
Mouse
regulation of hematopoietic stem cell proliferation GO:1902033 3 0.058
positive regulation of calcium mediated signaling GO:0050850 15 0.057
regulation of t helper 2 cell cytokine production GO:2000551 3 0.057
blood circulation GO:0008015 195 0.057
calcium mediated signaling GO:0019722 46 0.057
lymphocyte activation involved in immune response GO:0002285 93 0.057
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.057
reactive oxygen species biosynthetic process GO:1903409 8 0.055
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.055
purine nucleotide metabolic process GO:0006163 302 0.055
organic hydroxy compound transport GO:0015850 93 0.055
serotonin secretion by mast cell GO:0002552 1 0.055
regulation of hormone levels GO:0010817 211 0.053
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.053
negative regulation of mast cell degranulation GO:0043305 4 0.053
leukocyte migration GO:0050900 124 0.053
placenta development GO:0001890 140 0.053
chemokine metabolic process GO:0050755 10 0.053
nucleotide biosynthetic process GO:0009165 78 0.052
regulation of toll like receptor signaling pathway GO:0034121 20 0.052
modification of morphology or physiology of other organism GO:0035821 18 0.052
positive regulation of nucleotide metabolic process GO:0045981 114 0.051
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.051
regulation of mast cell activation GO:0033003 21 0.051
b cell chemotaxis GO:0035754 3 0.051
positive regulation of cell migration GO:0030335 109 0.050
interaction with symbiont GO:0051702 14 0.050
response to oxidative stress GO:0006979 123 0.050
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.050
t cell activation involved in immune response GO:0002286 43 0.050
positive regulation of cell death GO:0010942 224 0.049
circulatory system process GO:0003013 197 0.049
positive regulation of lymphocyte activation GO:0051251 140 0.049
antibacterial humoral response GO:0019731 8 0.048
phosphatidylinositol mediated signaling GO:0048015 41 0.048
regulation of serotonin secretion GO:0014062 3 0.047
regulation of production of molecular mediator of immune response GO:0002700 65 0.047
regulation of body fluid levels GO:0050878 162 0.047
interleukin 8 production GO:0032637 4 0.046
regulation of defense response to fungus GO:1900150 1 0.046
regulation of protein kinase b signaling GO:0051896 56 0.046
peptide secretion GO:0002790 114 0.046
antimicrobial peptide secretion GO:0002776 1 0.046
leukocyte migration involved in inflammatory response GO:0002523 7 0.046
regulation of macrophage activation GO:0043030 17 0.046
regulation of nucleotide metabolic process GO:0006140 169 0.045
lipid transport GO:0006869 98 0.045
membrane organization GO:0061024 245 0.045
regulation of t cell differentiation GO:0045580 83 0.045
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.045
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.045
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.045
interleukin 33 mediated signaling pathway GO:0038172 1 0.044
macrophage differentiation GO:0030225 20 0.044
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.044
negative regulation of molecular function GO:0044092 258 0.044
cell adhesion GO:0007155 329 0.044
carbohydrate metabolic process GO:0005975 230 0.044
humoral immune response mediated by circulating immunoglobulin GO:0002455 14 0.044
Mouse
cellular amino acid metabolic process GO:0006520 103 0.043
negative regulation of inflammatory response GO:0050728 61 0.043
killing by host of symbiont cells GO:0051873 11 0.043
neutrophil mediated killing of fungus GO:0070947 3 0.043
cellular nitrogen compound catabolic process GO:0044270 280 0.043
regulation of angiogenesis GO:0045765 81 0.043
regulation of jun kinase activity GO:0043506 40 0.042
response to acid chemical GO:0001101 111 0.042
muscle system process GO:0003012 141 0.042
regulation of neutrophil mediated killing of fungus GO:0070953 1 0.042
t helper 2 cell cytokine production GO:0035745 4 0.042
calcium ion homeostasis GO:0055074 127 0.041
Mouse
nucleoside metabolic process GO:0009116 246 0.041
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.041
regulation of macrophage chemotaxis GO:0010758 8 0.041
positive regulation of map kinase activity GO:0043406 84 0.041
protein localization to organelle GO:0033365 185 0.041
protein kinase b signaling GO:0043491 74 0.041
positive regulation of thymocyte migration GO:2000412 2 0.041
leukocyte apoptotic process GO:0071887 71 0.040
cellular response to organonitrogen compound GO:0071417 145 0.040
positive regulation of neutrophil mediated killing of fungus GO:0070965 1 0.040
t helper 1 cell differentiation GO:0045063 13 0.040
cellular ketone metabolic process GO:0042180 84 0.039
positive regulation of antimicrobial humoral response GO:0002760 2 0.039
positive regulation of t cell differentiation GO:0045582 52 0.039
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.038
regulation of muscle tissue development GO:1901861 97 0.038
regulation of antimicrobial humoral response GO:0002759 3 0.038
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.038
wound healing involved in inflammatory response GO:0002246 4 0.037
activation of jun kinase activity GO:0007257 15 0.037
purine ribonucleotide metabolic process GO:0009150 290 0.037
production of molecular mediator of immune response GO:0002440 103 0.036
cellular amide metabolic process GO:0043603 58 0.036
regulation of alpha beta t cell activation GO:0046634 53 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
positive regulation of transferase activity GO:0051347 167 0.036
acute phase response GO:0006953 10 0.036
mucosal immune response GO:0002385 13 0.035
regulation of exocytosis GO:0017157 61 0.035
regulation of eosinophil migration GO:2000416 2 0.035
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
positive regulation of fat cell differentiation GO:0045600 32 0.035
transepithelial chloride transport GO:0030321 4 0.035
regulation of neutrophil mediated cytotoxicity GO:0070948 2 0.035
response to peptidoglycan GO:0032494 9 0.035
purine nucleoside catabolic process GO:0006152 205 0.034
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.034
cellular response to growth factor stimulus GO:0071363 197 0.034
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.033
amino sugar catabolic process GO:0046348 1 0.033
positive regulation of macrophage activation GO:0043032 10 0.033
response to transforming growth factor beta GO:0071559 88 0.033
muscle contraction GO:0006936 101 0.033
fever generation GO:0001660 7 0.033
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.033
positive regulation of behavior GO:0048520 40 0.033
neutrophil mediated killing of symbiont cell GO:0070943 8 0.032
eosinophil migration GO:0072677 3 0.032
regulation of jnk cascade GO:0046328 62 0.032
thymocyte migration GO:0072679 2 0.032
muscle tissue development GO:0060537 308 0.032
protein targeting GO:0006605 143 0.032
embryonic placenta development GO:0001892 98 0.032
positive regulation of interleukin 8 production GO:0032757 2 0.032
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.032
organic hydroxy compound metabolic process GO:1901615 203 0.031
innate immune response in mucosa GO:0002227 3 0.031
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.031
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.031
positive regulation of b cell chemotaxis GO:2000538 2 0.031
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.031
angiogenesis GO:0001525 201 0.031
acute inflammatory response GO:0002526 41 0.031
regulation of vitamin d biosynthetic process GO:0060556 1 0.030
cellular response to acid chemical GO:0071229 68 0.030
mapk cascade GO:0000165 281 0.030
cyclic nucleotide metabolic process GO:0009187 59 0.030
regulation of ossification GO:0030278 112 0.030
glycosyl compound metabolic process GO:1901657 246 0.030
negative regulation of nervous system development GO:0051961 156 0.030
tissue homeostasis GO:0001894 115 0.030
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.030
positive regulation of t cell proliferation GO:0042102 52 0.029
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.029
single organism nuclear import GO:1902593 95 0.029
aromatic compound catabolic process GO:0019439 286 0.029
skeletal muscle organ development GO:0060538 163 0.029
cell death in response to oxidative stress GO:0036473 24 0.029
carbohydrate derivative catabolic process GO:1901136 231 0.029
immunoglobulin production in mucosal tissue GO:0002426 3 0.029
epithelial cell proliferation GO:0050673 174 0.029
detection of molecule of bacterial origin GO:0032490 2 0.028
positive regulation of killing of cells of other organism GO:0051712 3 0.028
regulation of nitric oxide biosynthetic process GO:0045428 18 0.028
nucleocytoplasmic transport GO:0006913 139 0.028
connective tissue development GO:0061448 179 0.027
organic acid transport GO:0015849 101 0.027
ras protein signal transduction GO:0007265 77 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
activation of mapk activity GO:0000187 59 0.027
type 2 immune response GO:0042092 23 0.027
regulation of ras protein signal transduction GO:0046578 114 0.027
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.027
protein catabolic process GO:0030163 221 0.026
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.026
negative regulation of phosphorus metabolic process GO:0010563 184 0.026
nuclear import GO:0051170 95 0.026
regulation of lymphocyte differentiation GO:0045619 107 0.026
nucleotide metabolic process GO:0009117 332 0.026
neuron death GO:0070997 154 0.026
positive regulation of jun kinase activity GO:0043507 30 0.026
negative regulation of muscle cell differentiation GO:0051148 33 0.026
glycoprotein biosynthetic process GO:0009101 89 0.026
regulation of t helper 1 type immune response GO:0002825 17 0.026
negative regulation of myoblast differentiation GO:0045662 18 0.026
intracellular protein transport GO:0006886 204 0.026
interleukin 12 production GO:0032615 32 0.026
regulation of hydrolase activity GO:0051336 246 0.026
regulation of cell migration GO:0030334 219 0.026
regulation of intracellular protein transport GO:0033157 82 0.026
regulation of immunoglobulin production GO:0002637 42 0.026
regulation of binding GO:0051098 111 0.025
extracellular matrix organization GO:0030198 147 0.025
organ or tissue specific immune response GO:0002251 13 0.025
negative regulation of chemokine biosynthetic process GO:0045079 2 0.025
cellular response to peptidoglycan GO:0071224 4 0.025
purine containing compound biosynthetic process GO:0072522 70 0.025
negative regulation of intracellular signal transduction GO:1902532 167 0.025
skeletal system morphogenesis GO:0048705 203 0.025
epithelial tube morphogenesis GO:0060562 303 0.025
cdc42 protein signal transduction GO:0032488 0 0.025
inositol lipid mediated signaling GO:0048017 41 0.025
transcription factor import into nucleus GO:0042991 26 0.025
positive regulation of eosinophil migration GO:2000418 2 0.025
cellular amine metabolic process GO:0044106 44 0.025
regulation of myotube differentiation GO:0010830 62 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
ion transmembrane transport GO:0034220 361 0.024
microglia development GO:0014005 2 0.024
negative regulation of macrophage chemotaxis GO:0010760 1 0.024
positive regulation of phagocytosis GO:0050766 26 0.024
Mouse
regulation of natural killer cell chemotaxis GO:2000501 1 0.024
positive regulation of intracellular protein transport GO:0090316 42 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
granulocyte migration GO:0097530 43 0.024
regulation of acute inflammatory response to non antigenic stimulus GO:0002877 2 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
defense response to gram negative bacterium GO:0050829 28 0.024
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.024
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
interferon beta biosynthetic process GO:0045350 4 0.024

Clec4e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.254
disease of cellular proliferation DOID:14566 0 0.254
organ system cancer DOID:0050686 0 0.106
respiratory system disease DOID:1579 0 0.045
disease of anatomical entity DOID:7 0 0.045
immune system disease DOID:2914 0 0.040