Mus musculus

12 known processes

Tmem119

transmembrane protein 119

(Aliases: MGC38046,AW208946,obif,BC025600)

Tmem119 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal system development GO:0001501 356 0.228
extracellular structure organization GO:0043062 148 0.217
skeletal system morphogenesis GO:0048705 203 0.144
cellular amino acid metabolic process GO:0006520 103 0.122
bone development GO:0060348 120 0.110
cell substrate adhesion GO:0031589 130 0.103
extracellular matrix organization GO:0030198 147 0.101
cell adhesion GO:0007155 329 0.083
lung development GO:0030324 164 0.082
epithelial tube morphogenesis GO:0060562 303 0.078
renal system development GO:0072001 225 0.078
urogenital system development GO:0001655 261 0.076
connective tissue development GO:0061448 179 0.070
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.069
response to organonitrogen compound GO:0010243 246 0.067
skeletal muscle organ development GO:0060538 163 0.065
mesonephros development GO:0001823 97 0.064
kidney development GO:0001822 213 0.064
cardiac chamber morphogenesis GO:0003206 93 0.063
respiratory tube development GO:0030323 167 0.062
cellular response to organonitrogen compound GO:0071417 145 0.062
negative regulation of immune system process GO:0002683 209 0.061
ossification GO:0001503 216 0.058
cartilage development GO:0051216 140 0.057
protein maturation GO:0051604 176 0.054
regulation of cell motility GO:2000145 236 0.054
positive regulation of cellular component biogenesis GO:0044089 94 0.052
chondrocyte differentiation GO:0002062 72 0.052
nucleoside phosphate metabolic process GO:0006753 338 0.052
limb development GO:0060173 166 0.052
endochondral bone morphogenesis GO:0060350 50 0.050
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.049
limb morphogenesis GO:0035108 149 0.049
regulation of cartilage development GO:0061035 44 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.047
regulation of cellular component biogenesis GO:0044087 181 0.047
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.047
extrinsic apoptotic signaling pathway GO:0097191 126 0.046
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.046
embryonic epithelial tube formation GO:0001838 130 0.046
carbohydrate metabolic process GO:0005975 230 0.045
type b pancreatic cell proliferation GO:0044342 10 0.045
appendage morphogenesis GO:0035107 149 0.045
nephron development GO:0072006 109 0.043
response to amino acid GO:0043200 37 0.042
branching morphogenesis of an epithelial tube GO:0048754 159 0.041
positive regulation of programmed cell death GO:0043068 218 0.040
cell matrix adhesion GO:0007160 68 0.040
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.040
nucleotide metabolic process GO:0009117 332 0.039
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.039
embryonic appendage morphogenesis GO:0035113 126 0.039
protein hydroxylation GO:0018126 4 0.039
respiratory system development GO:0060541 190 0.039
organelle assembly GO:0070925 177 0.038
digestive tract development GO:0048565 190 0.038
oxidation reduction process GO:0055114 342 0.037
negative regulation of cell proliferation GO:0008285 296 0.037
embryonic limb morphogenesis GO:0030326 126 0.037
bone morphogenesis GO:0060349 78 0.037
positive regulation of cell death GO:0010942 224 0.037
single organism cell adhesion GO:0098602 156 0.037
kidney morphogenesis GO:0060993 83 0.037
rho protein signal transduction GO:0007266 32 0.036
response to oxidative stress GO:0006979 123 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
epithelial tube formation GO:0072175 130 0.035
protein processing GO:0016485 163 0.035
regulation of cell adhesion GO:0030155 154 0.034
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.034
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.034
cellular macromolecule catabolic process GO:0044265 206 0.034
blood vessel morphogenesis GO:0048514 285 0.033
inflammatory response GO:0006954 244 0.033
glycoprotein metabolic process GO:0009100 116 0.032
regionalization GO:0003002 337 0.032
digestive tract morphogenesis GO:0048546 147 0.031
cellular response to amino acid stimulus GO:0071230 29 0.031
nitrogen compound transport GO:0071705 271 0.031
spermatogenesis GO:0007283 284 0.031
small gtpase mediated signal transduction GO:0007264 97 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
ear development GO:0043583 200 0.030
anatomical structure maturation GO:0071695 49 0.030
heart morphogenesis GO:0003007 178 0.030
multicellular organismal homeostasis GO:0048871 164 0.030
hair follicle development GO:0001942 85 0.030
cellular response to hormone stimulus GO:0032870 150 0.030
regulation of proteolysis GO:0030162 164 0.030
carbohydrate derivative catabolic process GO:1901136 231 0.030
anatomical structure homeostasis GO:0060249 145 0.029
organ growth GO:0035265 117 0.029
regulation of apoptotic signaling pathway GO:2001233 197 0.029
skin morphogenesis GO:0043589 38 0.029
digestive system development GO:0055123 200 0.029
molting cycle GO:0042303 90 0.029
nephron tubule morphogenesis GO:0072078 68 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.028
muscle cell differentiation GO:0042692 261 0.028
cellular response to growth factor stimulus GO:0071363 197 0.028
oligosaccharide biosynthetic process GO:0009312 7 0.028
morphogenesis of embryonic epithelium GO:0016331 159 0.028
fat cell differentiation GO:0045444 160 0.028
regulation of chondrocyte differentiation GO:0032330 33 0.028
positive regulation of apoptotic process GO:0043065 217 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
reactive oxygen species metabolic process GO:0072593 84 0.027
collagen fibril organization GO:0030199 32 0.027
central nervous system vasculogenesis GO:0022009 3 0.027
palate development GO:0060021 76 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
nephron epithelium morphogenesis GO:0072088 68 0.027
tube formation GO:0035148 140 0.026
carbohydrate homeostasis GO:0033500 128 0.026
regulation of defense response GO:0031347 233 0.026
cell growth GO:0016049 130 0.026
organic cyclic compound catabolic process GO:1901361 295 0.025
head morphogenesis GO:0060323 34 0.025
nucleoside catabolic process GO:0009164 206 0.025
modification dependent protein catabolic process GO:0019941 133 0.025
negative regulation of cellular component organization GO:0051129 194 0.025
positive regulation of mapk cascade GO:0043410 170 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
regulation of neuron projection development GO:0010975 169 0.025
aromatic compound catabolic process GO:0019439 286 0.025
response to acid chemical GO:0001101 111 0.024
negative regulation of apoptotic signaling pathway GO:2001234 104 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
trabecula formation GO:0060343 24 0.024
cell type specific apoptotic process GO:0097285 268 0.024
negative regulation of cell migration GO:0030336 59 0.024
positive regulation of cell development GO:0010720 237 0.024
positive regulation of protein modification process GO:0031401 299 0.024
apoptotic signaling pathway GO:0097190 306 0.024
regulation of hydrolase activity GO:0051336 246 0.024
regulation of rho protein signal transduction GO:0035023 71 0.024
macromolecule catabolic process GO:0009057 281 0.024
defense response to other organism GO:0098542 197 0.024
glucose homeostasis GO:0042593 128 0.023
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.023
response to inorganic substance GO:0010035 96 0.023
negative regulation of epithelial cell proliferation GO:0050680 64 0.023
cellular response to acid chemical GO:0071229 68 0.023
innate immune response GO:0045087 157 0.023
skin development GO:0043588 220 0.023
striated muscle tissue development GO:0014706 293 0.023
regulation of ossification GO:0030278 112 0.022
mesonephric tubule morphogenesis GO:0072171 63 0.022
regulation of cellular response to stress GO:0080135 159 0.022
inner ear morphogenesis GO:0042472 101 0.022
regulation of actin filament based process GO:0032970 99 0.022
female gonad development GO:0008585 71 0.022
chemotaxis GO:0006935 247 0.022
cellular ketone metabolic process GO:0042180 84 0.022
positive regulation of cell substrate adhesion GO:0010811 47 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
growth plate cartilage development GO:0003417 14 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
ureteric bud morphogenesis GO:0060675 62 0.021
negative regulation of molecular function GO:0044092 258 0.021
cellular response to cytokine stimulus GO:0071345 189 0.021
lateral inhibition GO:0046331 1 0.021
peptidyl tyrosine phosphorylation GO:0018108 143 0.021
smoothened signaling pathway GO:0007224 105 0.021
purine containing compound metabolic process GO:0072521 311 0.021
peptidyl proline hydroxylation GO:0019511 3 0.021
circulatory system process GO:0003013 197 0.021
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
regulation of interleukin 8 production GO:0032677 3 0.020
response to organic cyclic compound GO:0014070 198 0.020
embryonic skeletal system morphogenesis GO:0048704 91 0.020
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.020
renal tubule development GO:0061326 87 0.020
positive regulation of proteolysis GO:0045862 85 0.020
regulation of muscle tissue development GO:1901861 97 0.020
defense response to bacterium GO:0042742 119 0.019
male gamete generation GO:0048232 285 0.019
midgut development GO:0007494 4 0.019
response to insulin GO:0032868 100 0.019
positive regulation of neuron differentiation GO:0045666 141 0.019
regulation of fat cell differentiation GO:0045598 81 0.019
regulation of cytoskeleton organization GO:0051493 122 0.019
kidney epithelium development GO:0072073 121 0.019
sensory organ morphogenesis GO:0090596 242 0.019
interleukin 8 production GO:0032637 4 0.019
establishment of planar polarity GO:0001736 28 0.019
odontogenesis GO:0042476 78 0.019
amine metabolic process GO:0009308 45 0.019
developmental maturation GO:0021700 193 0.019
ameboidal type cell migration GO:0001667 128 0.019
regulation of kinase activity GO:0043549 249 0.019
artery development GO:0060840 53 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
cellular response to thyroid hormone stimulus GO:0097067 1 0.019
cardiac chamber development GO:0003205 108 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
negative regulation of cell development GO:0010721 169 0.019
gastrulation GO:0007369 116 0.018
regulation of cell migration GO:0030334 219 0.018
negative regulation of synapse assembly GO:0051964 3 0.018
myeloid leukocyte migration GO:0097529 57 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
cellular response to lipid GO:0071396 145 0.018
ubiquitin dependent protein catabolic process GO:0006511 129 0.018
trabecula morphogenesis GO:0061383 40 0.018
protein catabolic process GO:0030163 221 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
cellular protein catabolic process GO:0044257 155 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
negative regulation of gastrulation GO:2000542 3 0.018
multi multicellular organism process GO:0044706 109 0.017
response to growth factor GO:0070848 198 0.017
appendage development GO:0048736 166 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
biomineral tissue development GO:0031214 64 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
actin cytoskeleton organization GO:0030036 220 0.017
cellular chemical homeostasis GO:0055082 215 0.017
cellular modified amino acid metabolic process GO:0006575 63 0.017
regulation of angiogenesis GO:0045765 81 0.017
gland development GO:0048732 330 0.017
regulation of response to wounding GO:1903034 189 0.017
guanosine containing compound catabolic process GO:1901069 144 0.017
negative regulation of neuron differentiation GO:0045665 101 0.017
peptidyl amino acid modification GO:0018193 336 0.017
morphogenesis of a branching structure GO:0001763 203 0.017
wound healing GO:0042060 157 0.017
regulation of hormone levels GO:0010817 211 0.017
gtp metabolic process GO:0046039 144 0.016
focal adhesion assembly GO:0048041 19 0.016
endoderm development GO:0007492 45 0.016
glycoprotein biosynthetic process GO:0009101 89 0.016
somatotropin secreting cell differentiation GO:0060126 4 0.016
regulation of blood pressure GO:0008217 93 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
gtp catabolic process GO:0006184 143 0.016
interleukin 8 secretion GO:0072606 3 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
telencephalon development GO:0021537 186 0.016
negative regulation of phospholipase activity GO:0010519 4 0.016
nephron tubule development GO:0072080 84 0.016
camera type eye development GO:0043010 266 0.016
ear morphogenesis GO:0042471 118 0.016
protein oligomerization GO:0051259 67 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.016
regulation of organelle organization GO:0033043 289 0.016
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.016
establishment of tissue polarity GO:0007164 28 0.016
muscle tissue morphogenesis GO:0060415 53 0.016
negative regulation of cytokine production GO:0001818 84 0.015
protein ubiquitination GO:0016567 171 0.015
ras protein signal transduction GO:0007265 77 0.015
regulation of secretion GO:0051046 274 0.015
organophosphate catabolic process GO:0046434 232 0.015
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation GO:0044343 1 0.015
regulation of homeostatic process GO:0032844 182 0.015
ureteric bud development GO:0001657 94 0.015
small molecule biosynthetic process GO:0044283 132 0.015
cardiac ventricle development GO:0003231 83 0.015
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.015
renal tubule morphogenesis GO:0061333 72 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
neural tube development GO:0021915 160 0.015
regulation of cytokine production GO:0001817 266 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
collagen metabolic process GO:0032963 17 0.015
activation of immune response GO:0002253 138 0.015
response to peptide hormone GO:0043434 127 0.015
mesendoderm development GO:0048382 3 0.014
negative regulation of ossification GO:0030279 49 0.014
cell fate commitment GO:0045165 210 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
endochondral bone growth GO:0003416 19 0.014
forebrain development GO:0030900 302 0.014
metanephric loop of henle development GO:0072236 4 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
polysaccharide metabolic process GO:0005976 39 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
peptide transport GO:0015833 133 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
sulfur compound metabolic process GO:0006790 100 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
tissue homeostasis GO:0001894 115 0.014
peripheral nervous system axon regeneration GO:0014012 2 0.013
positive regulation of cell adhesion GO:0045785 80 0.013
monosaccharide metabolic process GO:0005996 106 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
antibacterial peptide secretion GO:0002779 1 0.013
cardiac muscle tissue development GO:0048738 130 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
antimicrobial peptide secretion GO:0002776 1 0.013
rhythmic process GO:0048511 174 0.013
regulation of mapk cascade GO:0043408 248 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
epithelial cell development GO:0002064 159 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.013
cellular amine metabolic process GO:0044106 44 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
stem cell differentiation GO:0048863 268 0.013
regulation of neuron differentiation GO:0045664 281 0.013
positive regulation of interleukin 8 production GO:0032757 2 0.013
regulation of cell substrate adhesion GO:0010810 73 0.013
carbohydrate biosynthetic process GO:0016051 74 0.013
regulation of cellular response to oxidative stress GO:1900407 19 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
positive regulation of nervous system development GO:0051962 221 0.013
cytokine mediated signaling pathway GO:0019221 115 0.013
nephron epithelium development GO:0072009 92 0.013
regulation of cell projection organization GO:0031344 206 0.013
regulation of binding GO:0051098 111 0.013
nephron morphogenesis GO:0072028 69 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
response to monosaccharide GO:0034284 67 0.013
negative regulation of lipoprotein lipase activity GO:0051005 1 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
alcohol metabolic process GO:0006066 116 0.013
cytokine production GO:0001816 319 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
regulation of glucose metabolic process GO:0010906 60 0.012
organelle fission GO:0048285 170 0.012
blood circulation GO:0008015 195 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
neurotransmitter transport GO:0006836 76 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
ventricular septum development GO:0003281 42 0.012
positive regulation of ossification GO:0045778 47 0.012
regulation of chemotaxis GO:0050920 53 0.012
regulation of osteoblast differentiation GO:0045667 67 0.012
melanocyte differentiation GO:0030318 25 0.012
positive regulation of transferase activity GO:0051347 167 0.012
positive regulation of intracellular transport GO:0032388 70 0.012
purine nucleotide metabolic process GO:0006163 302 0.012
cell cell junction organization GO:0045216 72 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
mesonephric duct morphogenesis GO:0072180 4 0.012
chondrocyte development GO:0002063 24 0.012
tissue migration GO:0090130 68 0.012
hair cycle GO:0042633 90 0.012
spinal cord development GO:0021510 81 0.012
positive regulation of defense response GO:0031349 124 0.012
hindbrain morphogenesis GO:0021575 46 0.012
gonad development GO:0008406 141 0.012
glucose metabolic process GO:0006006 92 0.012
endothelium development GO:0003158 45 0.012
stem cell development GO:0048864 219 0.012
leukocyte migration GO:0050900 124 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
determination of left right symmetry GO:0007368 80 0.012
response to transforming growth factor beta GO:0071559 88 0.012
actomyosin structure organization GO:0031032 56 0.012
cation homeostasis GO:0055080 212 0.011
positive regulation of neuron projection development GO:0010976 79 0.011
positive regulation of organelle organization GO:0010638 128 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
cellular response to oxidative stress GO:0034599 76 0.011
regulation of protein catabolic process GO:0042176 108 0.011
oocyte construction GO:0007308 2 0.011
epidermis development GO:0008544 187 0.011
regulation of map kinase activity GO:0043405 120 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
meiotic nuclear division GO:0007126 115 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
antibacterial peptide production GO:0002778 2 0.011
female sex differentiation GO:0046660 84 0.011
angiogenesis GO:0001525 201 0.011
organic acid biosynthetic process GO:0016053 86 0.011
negative regulation of fat cell differentiation GO:0045599 36 0.011
face development GO:0060324 38 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
cardiac septum development GO:0003279 59 0.011
regulation of protein binding GO:0043393 60 0.011
positive regulation of homeostatic process GO:0032846 64 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
detection of stimulus GO:0051606 84 0.011
cellular response to external stimulus GO:0071496 88 0.011
cellular homeostasis GO:0019725 240 0.011
hexose metabolic process GO:0019318 98 0.011
cell migration involved in gastrulation GO:0042074 13 0.010
calcium ion homeostasis GO:0055074 127 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
morphogenesis of a polarized epithelium GO:0001738 37 0.010
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.010
hexose biosynthetic process GO:0019319 39 0.010
epithelial cell proliferation GO:0050673 174 0.010
generation of precursor metabolites and energy GO:0006091 103 0.010
bone mineralization GO:0030282 54 0.010
superoxide metabolic process GO:0006801 27 0.010
negative regulation of nervous system development GO:0051961 156 0.010
cardiac muscle cell differentiation GO:0055007 69 0.010
sequestering of calcium ion GO:0051208 18 0.010
cardiac muscle tissue morphogenesis GO:0055008 44 0.010
odontogenesis of dentin containing tooth GO:0042475 66 0.010
negative regulation of nodal signaling pathway GO:1900108 3 0.010

Tmem119 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.169
musculoskeletal system disease DOID:17 0 0.169
nervous system disease DOID:863 0 0.053
myopathy DOID:423 0 0.037
muscular disease DOID:0080000 0 0.037
muscle tissue disease DOID:66 0 0.037
bone disease DOID:0080001 0 0.033
connective tissue disease DOID:65 0 0.033
osteochondrodysplasia DOID:2256 0 0.021
bone development disease DOID:0080006 0 0.021
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.011
heart disease DOID:114 0 0.010
cardiomyopathy DOID:0050700 0 0.010
cardiovascular system disease DOID:1287 0 0.010