Mus musculus

0 known processes

Tmem115

transmembrane protein 115

(Aliases: Pl6,Pp6,C78915)

Tmem115 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular ketone metabolic process GO:0010565 66 0.170
regulation of transferase activity GO:0051338 263 0.140
cellular protein catabolic process GO:0044257 155 0.126
negative regulation of protein metabolic process GO:0051248 282 0.122
cellular ketone metabolic process GO:0042180 84 0.113
response to molecule of bacterial origin GO:0002237 143 0.105
mapk cascade GO:0000165 281 0.100
nitrogen compound transport GO:0071705 271 0.096
male gamete generation GO:0048232 285 0.088
regulation of defense response GO:0031347 233 0.085
regulation of anatomical structure size GO:0090066 178 0.083
cellular lipid metabolic process GO:0044255 323 0.074
negative regulation of molecular function GO:0044092 258 0.069
amine metabolic process GO:0009308 45 0.069
regulation of protein kinase activity GO:0045859 232 0.068
spermatogenesis GO:0007283 284 0.064
negative regulation of phosphorylation GO:0042326 166 0.061
endomembrane system organization GO:0010256 147 0.059
glycerolipid metabolic process GO:0046486 122 0.058
regulation of hydrolase activity GO:0051336 246 0.057
cellular amino acid metabolic process GO:0006520 103 0.056
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.056
regulation of feeding behavior GO:0060259 3 0.055
regulation of cellular amino acid metabolic process GO:0006521 5 0.053
regulation of protein localization GO:0032880 231 0.052
regulation of mapk cascade GO:0043408 248 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.051
negative regulation of phosphate metabolic process GO:0045936 184 0.050
cellular amine metabolic process GO:0044106 44 0.049
organic cyclic compound catabolic process GO:1901361 295 0.049
positive regulation of protein modification process GO:0031401 299 0.049
camera type eye development GO:0043010 266 0.048
peptidyl amino acid modification GO:0018193 336 0.047
response to organonitrogen compound GO:0010243 246 0.047
negative regulation of phosphorus metabolic process GO:0010563 184 0.046
metal ion homeostasis GO:0055065 189 0.045
acetylcholine transport GO:0015870 2 0.045
carbohydrate derivative catabolic process GO:1901136 231 0.044
cellular response to cytokine stimulus GO:0071345 189 0.043
nuclear division GO:0000280 158 0.043
regulation of protein serine threonine kinase activity GO:0071900 157 0.042
histone modification GO:0016570 159 0.042
positive regulation of protein kinase activity GO:0045860 144 0.040
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.040
embryonic organ morphogenesis GO:0048562 276 0.039
regulation of kinase activity GO:0043549 249 0.038
skeletal system morphogenesis GO:0048705 203 0.038
glycerolipid biosynthetic process GO:0045017 50 0.037
cellular nitrogen compound catabolic process GO:0044270 280 0.037
carbohydrate derivative biosynthetic process GO:1901137 183 0.036
heterocycle catabolic process GO:0046700 280 0.036
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
nucleotide metabolic process GO:0009117 332 0.036
embryonic placenta development GO:0001892 98 0.035
blood circulation GO:0008015 195 0.035
protein localization to nucleus GO:0034504 121 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.034
negative regulation of intracellular signal transduction GO:1902532 167 0.034
nucleoside phosphate catabolic process GO:1901292 222 0.034
positive regulation of kinase activity GO:0033674 155 0.034
protein localization to organelle GO:0033365 185 0.033
regulation of hormone levels GO:0010817 211 0.032
glycosyl compound catabolic process GO:1901658 206 0.032
ras protein signal transduction GO:0007265 77 0.032
regulation of proteolysis GO:0030162 164 0.032
chromatin modification GO:0016568 187 0.032
ribonucleoside triphosphate catabolic process GO:0009203 199 0.032
ribose phosphate metabolic process GO:0019693 291 0.031
organonitrogen compound catabolic process GO:1901565 264 0.031
purine nucleoside catabolic process GO:0006152 205 0.031
circulatory system process GO:0003013 197 0.031
embryonic skeletal system development GO:0048706 120 0.031
glucose homeostasis GO:0042593 128 0.031
regulation of secretion by cell GO:1903530 249 0.030
positive regulation of cell death GO:0010942 224 0.030
purine containing compound metabolic process GO:0072521 311 0.030
regulation of intracellular transport GO:0032386 159 0.030
cellular response to lipid GO:0071396 145 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
endocytosis GO:0006897 168 0.029
modification dependent protein catabolic process GO:0019941 133 0.029
immune response regulating signaling pathway GO:0002764 125 0.029
protein kinase b signaling GO:0043491 74 0.029
negative regulation of cellular amine metabolic process GO:0033239 1 0.028
cellular response to molecule of bacterial origin GO:0071219 83 0.028
regulation of secretion GO:0051046 274 0.028
cytoplasmic transport GO:0016482 234 0.028
regulation of chromatin silencing GO:0031935 2 0.028
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.028
cellular response to biotic stimulus GO:0071216 92 0.028
cellular response to hormone stimulus GO:0032870 150 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
macromolecule catabolic process GO:0009057 281 0.027
acetylcholine secretion neurotransmission GO:0014055 2 0.027
synaptic transmission GO:0007268 329 0.027
action potential GO:0001508 78 0.027
apoptotic signaling pathway GO:0097190 306 0.027
negative regulation of chromatin silencing GO:0031936 1 0.027
negative regulation of protein phosphorylation GO:0001933 126 0.026
protein catabolic process GO:0030163 221 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
positive regulation of organelle organization GO:0010638 128 0.026
response to growth factor GO:0070848 198 0.026
positive regulation of mapk cascade GO:0043410 170 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
regulation of lipid metabolic process GO:0019216 118 0.026
regulation of cell migration GO:0030334 219 0.026
amide transport GO:0042886 138 0.025
protein targeting GO:0006605 143 0.025
regulation of cell division GO:0051302 76 0.025
regulation of lymphocyte activation GO:0051249 240 0.025
negative regulation of transferase activity GO:0051348 85 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
cellular homeostasis GO:0019725 240 0.024
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.024
regulation of t cell differentiation GO:0045580 83 0.024
cellular ion homeostasis GO:0006873 165 0.023
regulation of organelle organization GO:0033043 289 0.023
t cell activation GO:0042110 289 0.023
regulation of protein import into nucleus GO:0042306 52 0.023
regulation of t cell activation GO:0050863 170 0.023
membrane organization GO:0061024 245 0.023
positive regulation of intracellular transport GO:0032388 70 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.023
positive regulation of cell projection organization GO:0031346 95 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.022
meiotic nuclear division GO:0007126 115 0.022
hepatocyte growth factor receptor signaling pathway GO:0048012 3 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
extrinsic apoptotic signaling pathway GO:0097191 126 0.021
placenta development GO:0001890 140 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
organophosphate catabolic process GO:0046434 232 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
nuclear import GO:0051170 95 0.021
lipid biosynthetic process GO:0008610 179 0.021
nucleoside monophosphate metabolic process GO:0009123 85 0.021
response to peptide hormone GO:0043434 127 0.021
regulation of system process GO:0044057 200 0.021
ameboidal type cell migration GO:0001667 128 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
organ growth GO:0035265 117 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
nucleotide catabolic process GO:0009166 217 0.021
antimicrobial peptide production GO:0002775 2 0.020
dna metabolic process GO:0006259 303 0.020
amino sugar catabolic process GO:0046348 1 0.020
peptide hormone secretion GO:0030072 109 0.020
leukocyte differentiation GO:0002521 342 0.020
nucleoside metabolic process GO:0009116 246 0.020
neutral lipid metabolic process GO:0006638 57 0.020
positive regulation of secretion GO:0051047 130 0.020
nucleoside catabolic process GO:0009164 206 0.020
glycerophospholipid metabolic process GO:0006650 71 0.020
peptide transport GO:0015833 133 0.020
establishment of protein localization to organelle GO:0072594 118 0.020
sterol homeostasis GO:0055092 45 0.020
muscle tissue development GO:0060537 308 0.020
regulation of cell projection organization GO:0031344 206 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.020
cation homeostasis GO:0055080 212 0.019
acetate ester transport GO:1901374 2 0.019
spermatid differentiation GO:0048515 115 0.019
transmission of nerve impulse GO:0019226 76 0.019
protein import GO:0017038 101 0.019
negative regulation of kinase activity GO:0033673 81 0.019
cellular response to peptide hormone stimulus GO:0071375 92 0.019
regulation of cell activation GO:0050865 289 0.018
protein acylation GO:0043543 64 0.018
peptide secretion GO:0002790 114 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
response to light stimulus GO:0009416 135 0.018
maintenance of location GO:0051235 89 0.018
hormone secretion GO:0046879 128 0.018
stress activated mapk cascade GO:0051403 80 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
embryonic skeletal system morphogenesis GO:0048704 91 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
regulation of membrane potential GO:0042391 192 0.018
cardiac muscle tissue development GO:0048738 130 0.018
cellular response to lipopolysaccharide GO:0071222 77 0.018
positive regulation of cell development GO:0010720 237 0.018
purine containing compound catabolic process GO:0072523 213 0.018
regulation of homeostatic process GO:0032844 182 0.018
fat cell differentiation GO:0045444 160 0.018
regulation of protein targeting GO:1903533 61 0.017
skin development GO:0043588 220 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
response to transforming growth factor beta GO:0071559 88 0.017
rhodopsin mediated signaling pathway GO:0016056 4 0.017
regulation of reproductive process GO:2000241 66 0.017
anion transport GO:0006820 177 0.017
regulation of lymphocyte differentiation GO:0045619 107 0.017
defense response to other organism GO:0098542 197 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
negative regulation of cell cycle GO:0045786 123 0.017
developmental maturation GO:0021700 193 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
positive regulation of transferase activity GO:0051347 167 0.017
ossification GO:0001503 216 0.017
sensory perception GO:0007600 245 0.016
insulin secretion GO:0030073 89 0.016
proteasomal protein catabolic process GO:0010498 98 0.016
positive regulation of map kinase activity GO:0043406 84 0.016
regulation of peptide transport GO:0090087 91 0.016
response to lipopolysaccharide GO:0032496 128 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
stress activated protein kinase signaling cascade GO:0031098 81 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
regulation of body fluid levels GO:0050878 162 0.016
ensheathment of neurons GO:0007272 76 0.016
phospholipid metabolic process GO:0006644 87 0.016
response to temperature stimulus GO:0009266 55 0.016
response to organic cyclic compound GO:0014070 198 0.015
regulation of extent of cell growth GO:0061387 52 0.015
lymphocyte differentiation GO:0030098 242 0.015
multi multicellular organism process GO:0044706 109 0.015
nuclear transport GO:0051169 139 0.015
cell fate commitment GO:0045165 210 0.015
regulation of osteoblast differentiation GO:0045667 67 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
protein methylation GO:0006479 81 0.015
cytokine mediated signaling pathway GO:0019221 115 0.015
connective tissue development GO:0061448 179 0.015
heart process GO:0003015 94 0.015
cholesterol storage GO:0010878 4 0.015
regulation of ossification GO:0030278 112 0.015
regulation of defense response to bacterium GO:1900424 3 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
protein ubiquitination GO:0016567 171 0.015
immune response activating signal transduction GO:0002757 116 0.015
regulation of nuclear division GO:0051783 56 0.015
negative regulation of protein modification process GO:0031400 163 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
skeletal system development GO:0001501 356 0.015
digestive system development GO:0055123 200 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
organelle fission GO:0048285 170 0.015
transition metal ion homeostasis GO:0055076 54 0.015
regulation of multi organism process GO:0043900 111 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
aromatic compound catabolic process GO:0019439 286 0.015
phosphatidic acid biosynthetic process GO:0006654 2 0.015
blood vessel morphogenesis GO:0048514 285 0.014
carbohydrate metabolic process GO:0005975 230 0.014
regulation of blood pressure GO:0008217 93 0.014
t cell differentiation GO:0030217 174 0.014
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
cellular response to hepatocyte growth factor stimulus GO:0035729 2 0.014
activation of mapk activity GO:0000187 59 0.014
heart contraction GO:0060047 93 0.014
cell division GO:0051301 120 0.014
rho protein signal transduction GO:0007266 32 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.014
telencephalon development GO:0021537 186 0.014
gastrulation GO:0007369 116 0.014
neural tube development GO:0021915 160 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
macromolecule methylation GO:0043414 120 0.014
cell maturation GO:0048469 127 0.014
glycerophospholipid biosynthetic process GO:0046474 32 0.014
angiogenesis GO:0001525 201 0.014
regulation of cell motility GO:2000145 236 0.014
spermatid development GO:0007286 108 0.013
regulation of neuron projection development GO:0010975 169 0.013
response to radiation GO:0009314 165 0.013
oocyte maturation GO:0001556 18 0.013
axon ensheathment GO:0008366 76 0.013
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.013
peptidyl lysine modification GO:0018205 77 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
response to peptide GO:1901652 136 0.013
regulation of inflammatory response GO:0050727 147 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
nuclear membrane organization GO:0071763 4 0.013
calcium ion homeostasis GO:0055074 127 0.013
oxidation reduction process GO:0055114 342 0.013
protein import into nucleus GO:0006606 95 0.013
chromatin organization GO:0006325 206 0.013
positive regulation of phospholipase activity GO:0010518 3 0.013
urogenital system development GO:0001655 261 0.013
transcription factor import into nucleus GO:0042991 26 0.013
intracellular protein transport GO:0006886 204 0.013
histone methylation GO:0016571 71 0.012
negative regulation of gene silencing GO:0060969 2 0.012
cell adhesion GO:0007155 329 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
positive regulation of cellular component biogenesis GO:0044089 94 0.012
cation transport GO:0006812 399 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
regulation of map kinase activity GO:0043405 120 0.012
negative regulation of defense response GO:0031348 77 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
transmembrane transport GO:0055085 412 0.012
jnk cascade GO:0007254 72 0.012
muscle cell differentiation GO:0042692 261 0.012
cellular response to carbohydrate stimulus GO:0071322 50 0.012
regulation of monocyte chemotaxis GO:0090025 3 0.012
negative regulation of mapk cascade GO:0043409 65 0.012
regulation of phospholipase c activity GO:1900274 3 0.012
regulation of neuron differentiation GO:0045664 281 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
fertilization GO:0009566 127 0.012
chromatin silencing at rdna GO:0000183 3 0.012
positive regulation of binding GO:0051099 49 0.012
protein localization to membrane GO:0072657 108 0.012
regulation of cell cycle process GO:0010564 160 0.012
regulation of cytokine production GO:0001817 266 0.012
response to decreased oxygen levels GO:0036293 59 0.012
response to inorganic substance GO:0010035 96 0.012
negative regulation of protein tyrosine kinase activity GO:0061099 3 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
renal system development GO:0072001 225 0.012
appendage development GO:0048736 166 0.012
sequestering of calcium ion GO:0051208 18 0.012
positive regulation of osteoblast differentiation GO:0045669 34 0.012
positive regulation of secretion by cell GO:1903532 114 0.011
single organism nuclear import GO:1902593 95 0.011
regulation of lipid biosynthetic process GO:0046890 54 0.011
fucosylation GO:0036065 9 0.011
positive regulation of ossification GO:0045778 47 0.011
cardiac chamber morphogenesis GO:0003206 93 0.011
bone development GO:0060348 120 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
regulation of translational initiation by iron GO:0006447 2 0.011
steroid metabolic process GO:0008202 119 0.011
axonogenesis GO:0007409 274 0.011
neuronal action potential GO:0019228 54 0.011
fatty acid metabolic process GO:0006631 121 0.011
regulation of chromatin organization GO:1902275 57 0.011
carbohydrate homeostasis GO:0033500 128 0.011
membrane tubulation GO:0097320 4 0.011
cellular protein complex assembly GO:0043623 116 0.011
response to acid chemical GO:0001101 111 0.011
positive regulation of growth GO:0045927 104 0.011
substantia nigra development GO:0021762 2 0.011
regulation of chromosome organization GO:0033044 83 0.011
regulation of neurotransmitter transport GO:0051588 35 0.011
activation of adenylate cyclase activity GO:0007190 4 0.011
feeding behavior GO:0007631 62 0.011
rna splicing GO:0008380 54 0.011
response to hepatocyte growth factor GO:0035728 2 0.011
detection of external stimulus GO:0009581 61 0.011
defense response to bacterium GO:0042742 119 0.011
wnt signaling pathway GO:0016055 188 0.011
acylglycerol metabolic process GO:0006639 55 0.011
male gonad development GO:0008584 88 0.011
multicellular organismal aging GO:0010259 24 0.011
meiotic cell cycle GO:0051321 122 0.011
regulation of erk1 and erk2 cascade GO:0070372 71 0.011
response to monosaccharide GO:0034284 67 0.011
cytokine production GO:0001816 319 0.011
triglyceride metabolic process GO:0006641 51 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
regulation of chromatin modification GO:1903308 57 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
neuron death GO:0070997 154 0.010
chemotaxis GO:0006935 247 0.010
epithelial cell development GO:0002064 159 0.010
positive regulation of jnk cascade GO:0046330 46 0.010
negative regulation of immune system process GO:0002683 209 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
myeloid leukocyte activation GO:0002274 83 0.010
regulation of fatty acid metabolic process GO:0019217 28 0.010
regulation of dna binding GO:0051101 39 0.010
lipid localization GO:0010876 126 0.010
negative regulation of growth GO:0045926 99 0.010
fibroblast migration GO:0010761 21 0.010
lens development in camera type eye GO:0002088 62 0.010
activation of phospholipase c activity GO:0007202 2 0.010
regulation of cell growth GO:0001558 91 0.010

Tmem115 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.019
disease of anatomical entity DOID:7 0 0.019
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011