Mus musculus

0 known processes

Tmem116

transmembrane protein 116

(Aliases: C030022K24Rik,4930406A18Rik,4930513P12Rik)

Tmem116 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.327
transmembrane transport GO:0055085 412 0.290
cation transport GO:0006812 399 0.202
nitrogen compound transport GO:0071705 271 0.194
male gamete generation GO:0048232 285 0.131
inorganic ion transmembrane transport GO:0098660 234 0.130
spermatogenesis GO:0007283 284 0.115
cell maturation GO:0048469 127 0.093
cation transmembrane transport GO:0098655 266 0.079
positive regulation of peptide secretion GO:0002793 33 0.074
developmental maturation GO:0021700 193 0.071
kidney development GO:0001822 213 0.065
germ cell development GO:0007281 185 0.061
carboxylic acid transport GO:0046942 100 0.058
renal system development GO:0072001 225 0.058
peptide transport GO:0015833 133 0.052
organic acid transport GO:0015849 101 0.050
regulation of hormone levels GO:0010817 211 0.049
gonad development GO:0008406 141 0.047
locomotory behavior GO:0007626 195 0.046
synaptic transmission GO:0007268 329 0.046
embryonic epithelial tube formation GO:0001838 130 0.044
stem cell maintenance GO:0019827 130 0.044
inorganic cation transmembrane transport GO:0098662 207 0.044
cellular homeostasis GO:0019725 240 0.043
sodium ion transmembrane transport GO:0035725 49 0.042
amide transport GO:0042886 138 0.042
purine nucleotide metabolic process GO:0006163 302 0.041
urogenital system development GO:0001655 261 0.041
lateral inhibition GO:0046331 1 0.038
epithelial tube formation GO:0072175 130 0.037
protein modification by small protein conjugation or removal GO:0070647 207 0.037
anion transport GO:0006820 177 0.035
kidney epithelium development GO:0072073 121 0.034
regulation of peptide transport GO:0090087 91 0.034
cellular transition metal ion homeostasis GO:0046916 32 0.033
asymmetric stem cell division GO:0098722 3 0.033
male sex differentiation GO:0046661 109 0.033
regulation of cell cycle GO:0051726 281 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.032
stem cell development GO:0048864 219 0.032
regulation of striated muscle cell differentiation GO:0051153 81 0.031
aromatic compound catabolic process GO:0019439 286 0.030
regulation of membrane potential GO:0042391 192 0.030
inorganic anion transport GO:0015698 43 0.029
cellular chemical homeostasis GO:0055082 215 0.028
spermatid development GO:0007286 108 0.028
organic hydroxy compound transport GO:0015850 93 0.028
negative regulation of cell development GO:0010721 169 0.028
organic anion transport GO:0015711 137 0.028
multicellular organism growth GO:0035264 161 0.028
posttranscriptional regulation of gene expression GO:0010608 155 0.028
cellular lipid metabolic process GO:0044255 323 0.027
nucleotide metabolic process GO:0009117 332 0.027
tube formation GO:0035148 140 0.027
nucleoside triphosphate catabolic process GO:0009143 205 0.027
positive regulation of cell cycle GO:0045787 92 0.027
monovalent inorganic cation homeostasis GO:0055067 33 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.026
sensory organ morphogenesis GO:0090596 242 0.026
muscle tissue development GO:0060537 308 0.026
regulation of cellular catabolic process GO:0031329 242 0.026
specification of nephron tubule identity GO:0072081 5 0.026
cell type specific apoptotic process GO:0097285 268 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
epithelial cell development GO:0002064 159 0.025
cell fate commitment GO:0045165 210 0.025
myeloid cell differentiation GO:0030099 233 0.025
respiratory system development GO:0060541 190 0.025
regulation of ion transport GO:0043269 215 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
spermatid differentiation GO:0048515 115 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
stem cell proliferation GO:0072089 117 0.024
forebrain development GO:0030900 302 0.024
organonitrogen compound catabolic process GO:1901565 264 0.023
determination of left right symmetry GO:0007368 80 0.023
neural precursor cell proliferation GO:0061351 121 0.023
leukocyte differentiation GO:0002521 342 0.023
epidermis development GO:0008544 187 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
morphogenesis of embryonic epithelium GO:0016331 159 0.023
dna metabolic process GO:0006259 303 0.023
anion transmembrane transport GO:0098656 71 0.023
development of primary sexual characteristics GO:0045137 143 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
cell division GO:0051301 120 0.022
regulation of cell cycle process GO:0010564 160 0.022
adult behavior GO:0030534 135 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
hydrogen ion transmembrane transport GO:1902600 25 0.022
amino acid transport GO:0006865 61 0.022
purine containing compound metabolic process GO:0072521 311 0.022
sensory perception GO:0007600 245 0.022
peptide hormone secretion GO:0030072 109 0.021
transition metal ion homeostasis GO:0055076 54 0.021
neurotransmitter uptake GO:0001504 14 0.021
regulation of cell projection organization GO:0031344 206 0.021
catecholamine uptake involved in synaptic transmission GO:0051934 4 0.021
sodium ion transport GO:0006814 73 0.021
appendage development GO:0048736 166 0.021
regulation of myotube differentiation GO:0010830 62 0.021
neural tube formation GO:0001841 108 0.020
cardiac chamber development GO:0003205 108 0.020
embryonic heart tube morphogenesis GO:0003143 51 0.020
female gamete generation GO:0007292 74 0.020
determination of heart left right asymmetry GO:0061371 48 0.020
skin development GO:0043588 220 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
lung development GO:0030324 164 0.020
nucleoside metabolic process GO:0009116 246 0.019
multicellular organismal homeostasis GO:0048871 164 0.019
regionalization GO:0003002 337 0.019
positive regulation of cell development GO:0010720 237 0.019
positive regulation of growth GO:0045927 104 0.019
carnitine transport GO:0015879 3 0.019
regulation of neuron differentiation GO:0045664 281 0.019
regulation of peptide secretion GO:0002791 77 0.019
homeostasis of number of cells GO:0048872 210 0.018
regulation of neurotransmitter levels GO:0001505 87 0.018
nucleoside catabolic process GO:0009164 206 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
multicellular organismal signaling GO:0035637 91 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
somatic stem cell maintenance GO:0035019 47 0.018
nephron development GO:0072006 109 0.018
histamine transport GO:0051608 2 0.018
amino acid betaine metabolic process GO:0006577 7 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
respiratory tube development GO:0030323 167 0.017
organelle fission GO:0048285 170 0.017
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.017
amino acid transmembrane transport GO:0003333 37 0.017
regulation of ion transmembrane transport GO:0034765 119 0.017
transmission of nerve impulse GO:0019226 76 0.017
b 1 b cell homeostasis GO:0001922 4 0.017
mitochondrion organization GO:0007005 134 0.017
stem cell differentiation GO:0048863 268 0.017
neural tube development GO:0021915 160 0.017
central nervous system neuron differentiation GO:0021953 162 0.017
nucleotide catabolic process GO:0009166 217 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
spinal cord development GO:0021510 81 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
response to growth factor GO:0070848 198 0.016
macromolecule catabolic process GO:0009057 281 0.016
neurotransmitter transport GO:0006836 76 0.016
inclusion body assembly GO:0070841 3 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
specification of loop of henle identity GO:0072086 4 0.016
regulation of hydrolase activity GO:0051336 246 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
catecholamine uptake GO:0090493 4 0.016
pallium development GO:0021543 120 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
hypoxia inducible factor 1alpha signaling pathway GO:0097411 2 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
potassium ion homeostasis GO:0055075 4 0.016
membrane organization GO:0061024 245 0.016
response to peptide GO:1901652 136 0.016
mitotic cell cycle GO:0000278 195 0.015
cerebral cortex development GO:0021987 86 0.015
renal tubule development GO:0061326 87 0.015
hormone secretion GO:0046879 128 0.015
leukocyte homeostasis GO:0001776 79 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
proton transport GO:0015992 35 0.015
dopamine uptake GO:0090494 4 0.015
axonogenesis GO:0007409 274 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
negative regulation of nervous system development GO:0051961 156 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
metanephros development GO:0001656 79 0.015
myoblast differentiation GO:0045445 52 0.015
camera type eye development GO:0043010 266 0.014
oxygen homeostasis GO:0032364 2 0.014
regulation of muscle tissue development GO:1901861 97 0.014
circulatory system process GO:0003013 197 0.014
rhythmic process GO:0048511 174 0.014
tissue homeostasis GO:0001894 115 0.014
hydrogen transport GO:0006818 35 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
chemotaxis GO:0006935 247 0.014
negative regulation of cell cycle process GO:0010948 69 0.014
negative regulation of muscle cell differentiation GO:0051148 33 0.014
apoptotic signaling pathway GO:0097190 306 0.014
regulation of transmembrane transport GO:0034762 128 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
maternal determination of anterior posterior axis embryo GO:0008358 2 0.014
purine containing compound catabolic process GO:0072523 213 0.014
exocytosis GO:0006887 121 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
primary neural tube formation GO:0014020 95 0.014
positive regulation of hormone secretion GO:0046887 38 0.014
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.014
negative regulation of protein modification process GO:0031400 163 0.014
cation homeostasis GO:0055080 212 0.014
body fluid secretion GO:0007589 53 0.013
blood vessel morphogenesis GO:0048514 285 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.013
ureteric bud development GO:0001657 94 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
mesonephric epithelium development GO:0072163 94 0.013
regulation of neuron death GO:1901214 134 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
plasma membrane organization GO:0007009 90 0.013
neuron projection guidance GO:0097485 141 0.013
cardiac chamber morphogenesis GO:0003206 93 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
branch elongation involved in salivary gland morphogenesis GO:0060667 2 0.013
cardiac ventricle development GO:0003231 83 0.013
neuromuscular process GO:0050905 99 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
regulation of ion transmembrane transporter activity GO:0032412 54 0.013
myotube differentiation GO:0014902 105 0.013
skeletal system development GO:0001501 356 0.013
regulation of engulfment of apoptotic cell GO:1901074 2 0.013
compound eye development GO:0048749 1 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling GO:0003027 1 0.013
iron ion homeostasis GO:0055072 36 0.013
regulation of myeloid cell differentiation GO:0045637 96 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.012
gas homeostasis GO:0033483 3 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
neuroblast differentiation GO:0014016 2 0.012
negative regulation of protein metabolic process GO:0051248 282 0.012
blood circulation GO:0008015 195 0.012
insulin secretion GO:0030073 89 0.012
regulation of ph GO:0006885 26 0.012
cellular response to gonadotropin stimulus GO:0071371 4 0.012
heterocycle catabolic process GO:0046700 280 0.012
auditory receptor cell differentiation GO:0042491 37 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
response to oxidative stress GO:0006979 123 0.012
regulation of binding GO:0051098 111 0.012
lipid biosynthetic process GO:0008610 179 0.012
positive regulation of binding GO:0051099 49 0.012
neuron apoptotic process GO:0051402 142 0.012
neural fold elevation formation GO:0021502 1 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
neuronal action potential GO:0019228 54 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
hair cell differentiation GO:0035315 40 0.012
regulation of microtubule based process GO:0032886 52 0.012
negative regulation of molecular function GO:0044092 258 0.012
retina development in camera type eye GO:0060041 119 0.012
kidney morphogenesis GO:0060993 83 0.012
carnitine metabolic process GO:0009437 7 0.012
neuron neuron synaptic transmission GO:0007270 69 0.012
peptidyl lysine modification GO:0018205 77 0.012
retina morphogenesis in camera type eye GO:0060042 45 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
nephron epithelium development GO:0072009 92 0.012
divalent inorganic cation transport GO:0072511 178 0.012
positive regulation of growth hormone secretion GO:0060124 3 0.011
oocyte axis specification GO:0007309 2 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
cellular amino acid metabolic process GO:0006520 103 0.011
protein complex disassembly GO:0043241 40 0.011
muscle cell proliferation GO:0033002 52 0.011
cellular response to oxidative stress GO:0034599 76 0.011
response to monosaccharide GO:0034284 67 0.011
neuron death GO:0070997 154 0.011
monocarboxylic acid transport GO:0015718 44 0.011
metal ion homeostasis GO:0055065 189 0.011
cardiac muscle tissue development GO:0048738 130 0.011
microtubule based process GO:0007017 236 0.011
regulation of secretion by cell GO:1903530 249 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.011
cellular ion homeostasis GO:0006873 165 0.011
negative regulation of neuron death GO:1901215 98 0.011
gene silencing GO:0016458 38 0.011
columnar cuboidal epithelial cell maturation GO:0002069 4 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
carbohydrate homeostasis GO:0033500 128 0.011
general adaptation syndrome GO:0051866 2 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
muscle cell differentiation GO:0042692 261 0.010
myeloid cell homeostasis GO:0002262 114 0.010
positive regulation of sodium ion transmembrane transport GO:1902307 4 0.010
nephron tubule development GO:0072080 84 0.010

Tmem116 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
primary ciliary dyskinesia DOID:9562 0 0.067
disease of cellular proliferation DOID:14566 0 0.022
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.015
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010