Mus musculus

42 known processes

Aldh8a1

aldehyde dehydrogenase 8 family, member A1

(Aliases: Raldh4)

Aldh8a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
monocarboxylic acid metabolic process GO:0032787 191 0.407
oxidation reduction process GO:0055114 342 0.327
glucuronate metabolic process GO:0019585 2 0.282
fatty acid metabolic process GO:0006631 121 0.197
organic acid biosynthetic process GO:0016053 86 0.183
cellular lipid metabolic process GO:0044255 323 0.160
amino acid betaine transport GO:0015838 3 0.149
amino acid transmembrane transport GO:0003333 37 0.147
small molecule biosynthetic process GO:0044283 132 0.128
anion transmembrane transport GO:0098656 71 0.125
monocarboxylic acid biosynthetic process GO:0072330 61 0.122
amine metabolic process GO:0009308 45 0.115
lipid biosynthetic process GO:0008610 179 0.112
cofactor metabolic process GO:0051186 80 0.108
carboxylic acid biosynthetic process GO:0046394 86 0.104
fibrinolysis GO:0042730 3 0.102
anion transport GO:0006820 177 0.102
saturated monocarboxylic acid metabolic process GO:0032788 2 0.098
cellular response to cadmium ion GO:0071276 3 0.095
cellular amine metabolic process GO:0044106 44 0.092
diterpenoid biosynthetic process GO:0016102 7 0.091
carnitine transport GO:0015879 3 0.086
establishment of blood nerve barrier GO:0008065 3 0.085
regulation of cellular amine metabolic process GO:0033238 20 0.083
transmembrane transport GO:0055085 412 0.077
cell adhesion GO:0007155 329 0.077
cellular amino acid metabolic process GO:0006520 103 0.077
small molecule catabolic process GO:0044282 71 0.076
cellular ketone metabolic process GO:0042180 84 0.074
neutral lipid metabolic process GO:0006638 57 0.073
carnitine transmembrane transport GO:1902603 3 0.073
drug transmembrane transport GO:0006855 5 0.066
regulation of response to wounding GO:1903034 189 0.066
organic acid transport GO:0015849 101 0.063
nitrogen compound transport GO:0071705 271 0.060
regulation of hemostasis GO:1900046 28 0.060
regulation of cellular ketone metabolic process GO:0010565 66 0.060
ion transmembrane transport GO:0034220 361 0.058
organic hydroxy compound metabolic process GO:1901615 203 0.056
amino acid betaine metabolic process GO:0006577 7 0.053
organic cyclic compound catabolic process GO:1901361 295 0.053
nucleoside triphosphate metabolic process GO:0009141 230 0.052
response to organic cyclic compound GO:0014070 198 0.052
naphthalene metabolic process GO:0018931 1 0.052
coagulation GO:0050817 78 0.049
response to phenylpropanoid GO:0080184 22 0.049
cation transmembrane transport GO:0098655 266 0.049
blood coagulation GO:0007596 76 0.049
oxidative demethylation GO:0070989 1 0.048
response to stilbenoid GO:0035634 22 0.046
protein maturation GO:0051604 176 0.044
steroid metabolic process GO:0008202 119 0.043
wound healing GO:0042060 157 0.042
renal system process GO:0003014 48 0.041
negative regulation of molecular function GO:0044092 258 0.041
carbohydrate metabolic process GO:0005975 230 0.041
reactive oxygen species metabolic process GO:0072593 84 0.040
organic acid catabolic process GO:0016054 51 0.040
response to oxidative stress GO:0006979 123 0.040
renal tubular secretion GO:0097254 2 0.040
response to peptide GO:1901652 136 0.040
cytokine production GO:0001816 319 0.040
carboxylic acid transport GO:0046942 100 0.039
cellular response to organic cyclic compound GO:0071407 87 0.039
negative regulation of response to wounding GO:1903035 77 0.039
organonitrogen compound catabolic process GO:1901565 264 0.038
sulfur compound metabolic process GO:0006790 100 0.038
l alpha amino acid transmembrane transport GO:1902475 23 0.038
cation transport GO:0006812 399 0.038
regulation of hormone levels GO:0010817 211 0.037
spermatogenesis GO:0007283 284 0.037
regulation of coagulation GO:0050818 31 0.037
short chain fatty acid catabolic process GO:0019626 2 0.036
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.036
nucleoside metabolic process GO:0009116 246 0.036
terpenoid metabolic process GO:0006721 25 0.036
response to organonitrogen compound GO:0010243 246 0.036
organic anion transport GO:0015711 137 0.035
urate transport GO:0015747 1 0.035
alpha amino acid metabolic process GO:1901605 59 0.035
isoprenoid metabolic process GO:0006720 29 0.035
hemostasis GO:0007599 78 0.035
coenzyme metabolic process GO:0006732 52 0.034
regulation of reactive oxygen species metabolic process GO:2000377 40 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
regulation of blood coagulation GO:0030193 28 0.033
negative regulation of protein maturation GO:1903318 79 0.033
retinoic acid biosynthetic process GO:0002138 7 0.033
regulation of protein processing GO:0070613 96 0.033
glycerolipid metabolic process GO:0046486 122 0.033
purine nucleoside triphosphate metabolic process GO:0009144 226 0.032
protein processing GO:0016485 163 0.032
lipid localization GO:0010876 126 0.032
immune effector process GO:0002252 321 0.031
glycosyl compound metabolic process GO:1901657 246 0.031
carboxylic acid catabolic process GO:0046395 51 0.030
regulation of protein maturation GO:1903317 96 0.030
vitamin d biosynthetic process GO:0042368 3 0.030
inorganic ion transmembrane transport GO:0098660 234 0.030
aromatic compound catabolic process GO:0019439 286 0.029
macromolecule catabolic process GO:0009057 281 0.029
negative regulation of hemostasis GO:1900047 11 0.029
response to drug GO:0042493 75 0.029
amino acid transport GO:0006865 61 0.029
acylglycerol metabolic process GO:0006639 55 0.028
inorganic cation transmembrane transport GO:0098662 207 0.028
succinyl coa metabolic process GO:0006104 1 0.028
modified amino acid transport GO:0072337 5 0.028
angiogenesis GO:0001525 201 0.027
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.027
negative regulation of blood coagulation GO:0030195 11 0.026
organic hydroxy compound transport GO:0015850 93 0.025
organ regeneration GO:0031100 2 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.025
purine containing compound metabolic process GO:0072521 311 0.025
l amino acid transport GO:0015807 32 0.024
positive regulation of protein modification process GO:0031401 299 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
response to metal ion GO:0010038 47 0.024
amide transport GO:0042886 138 0.024
regulation of defense response GO:0031347 233 0.024
triglyceride metabolic process GO:0006641 51 0.024
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.024
extracellular matrix organization GO:0030198 147 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
cellular lipid catabolic process GO:0044242 52 0.024
cell substrate adhesion GO:0031589 130 0.024
cellular response to hormone stimulus GO:0032870 150 0.023
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.023
protein catabolic process GO:0030163 221 0.023
uronic acid metabolic process GO:0006063 2 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
c4 dicarboxylate transport GO:0015740 3 0.023
cellular homeostasis GO:0019725 240 0.023
male gamete generation GO:0048232 285 0.023
inter male aggressive behavior GO:0002121 3 0.023
cellular response to organonitrogen compound GO:0071417 145 0.022
regulation of kinase activity GO:0043549 249 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
negative regulation of protein metabolic process GO:0051248 282 0.022
regulation of proteolysis GO:0030162 164 0.022
progesterone metabolic process GO:0042448 4 0.022
multicellular organism growth GO:0035264 161 0.021
nucleoside monophosphate metabolic process GO:0009123 85 0.021
inositol lipid mediated signaling GO:0048017 41 0.021
cell growth GO:0016049 130 0.021
reactive nitrogen species metabolic process GO:2001057 0 0.021
divalent inorganic cation transport GO:0072511 178 0.021
regulation of system process GO:0044057 200 0.021
response to testosterone GO:0033574 3 0.021
organophosphate catabolic process GO:0046434 232 0.021
regulation of cellular amino acid metabolic process GO:0006521 5 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
glycoprotein metabolic process GO:0009100 116 0.021
9 cis retinoic acid metabolic process GO:0042905 5 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
regulation of body fluid levels GO:0050878 162 0.020
hormone metabolic process GO:0042445 86 0.020
phosphatidylinositol mediated signaling GO:0048015 41 0.020
sensory organ morphogenesis GO:0090596 242 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
cellular amino acid catabolic process GO:0009063 25 0.019
response to peptide hormone GO:0043434 127 0.019
metal ion homeostasis GO:0055065 189 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
regulation of cytokine production GO:0001817 266 0.019
fat cell differentiation GO:0045444 160 0.019
cellular response to peptide hormone stimulus GO:0071375 92 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
negative regulation of protein processing GO:0010955 79 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
tetrapyrrole metabolic process GO:0033013 22 0.019
negative regulation of hydrolase activity GO:0051346 71 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
response to inorganic substance GO:0010035 96 0.018
purine containing compound catabolic process GO:0072523 213 0.018
regulation of cell activation GO:0050865 289 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
heme metabolic process GO:0042168 16 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
regulation of peptidase activity GO:0052547 96 0.018
fatty acid derivative metabolic process GO:1901568 33 0.018
carnitine metabolic process GO:0009437 7 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
skin development GO:0043588 220 0.018
lipid transport GO:0006869 98 0.018
regulation of hydrolase activity GO:0051336 246 0.018
apoptotic signaling pathway GO:0097190 306 0.018
retinoid metabolic process GO:0001523 24 0.018
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.018
protein localization to organelle GO:0033365 185 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
cellular chemical homeostasis GO:0055082 215 0.018
folic acid containing compound metabolic process GO:0006760 3 0.018
cellular protein complex assembly GO:0043623 116 0.017
negative regulation of coagulation GO:0050819 11 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
atp metabolic process GO:0046034 75 0.017
monosaccharide metabolic process GO:0005996 106 0.017
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.017
sterol metabolic process GO:0016125 58 0.017
regulation of cell motility GO:2000145 236 0.017
positive regulation of cytokine production GO:0001819 174 0.017
regulation of anatomical structure size GO:0090066 178 0.017
intracellular protein transport GO:0006886 204 0.017
norepinephrine transport GO:0015874 2 0.017
protein modification by small protein conjugation GO:0032446 187 0.016
fatty acid biosynthetic process GO:0006633 41 0.016
peptidyl amino acid modification GO:0018193 336 0.016
lipid homeostasis GO:0055088 63 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
blood vessel morphogenesis GO:0048514 285 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
protein ubiquitination GO:0016567 171 0.016
cellular response to lipid GO:0071396 145 0.016
protein localization to nucleus GO:0034504 121 0.016
multi multicellular organism process GO:0044706 109 0.016
negative regulation of proteolysis GO:0045861 74 0.016
nucleoside catabolic process GO:0009164 206 0.016
cation homeostasis GO:0055080 212 0.016
fat soluble vitamin biosynthetic process GO:0042362 4 0.016
diterpenoid metabolic process GO:0016101 24 0.016
organic hydroxy compound catabolic process GO:1901616 25 0.016
cellular alcohol biosynthetic process GO:0044108 3 0.016
cellular response to cytokine stimulus GO:0071345 189 0.016
monocarboxylic acid transport GO:0015718 44 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
ribose phosphate metabolic process GO:0019693 291 0.015
peptidyl serine phosphorylation GO:0018105 74 0.015
dicarboxylic acid metabolic process GO:0043648 18 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
cytoplasmic transport GO:0016482 234 0.015
sodium ion transport GO:0006814 73 0.015
positive regulation of transferase activity GO:0051347 167 0.015
nucleotide catabolic process GO:0009166 217 0.015
regulation of protein kinase activity GO:0045859 232 0.015
isoprenoid biosynthetic process GO:0008299 9 0.015
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.015
ribonucleoside monophosphate catabolic process GO:0009158 57 0.015
cell type specific apoptotic process GO:0097285 268 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
camera type eye development GO:0043010 266 0.015
cell matrix adhesion GO:0007160 68 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
heterocycle catabolic process GO:0046700 280 0.015
extracellular structure organization GO:0043062 148 0.015
negative regulation of fibrinolysis GO:0051918 1 0.015
carbohydrate biosynthetic process GO:0016051 74 0.015
female meiosis chromosome segregation GO:0016321 1 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
positive regulation of activation of membrane attack complex GO:0001970 2 0.014
response to acid chemical GO:0001101 111 0.014
steroid biosynthetic process GO:0006694 47 0.014
positive regulation of angiogenesis GO:0045766 46 0.014
regulation of lipoprotein lipase activity GO:0051004 4 0.014
short chain fatty acid metabolic process GO:0046459 6 0.014
regulation of insulin receptor signaling pathway GO:0046626 21 0.014
maintenance of location GO:0051235 89 0.014
regulation of feeding behavior GO:0060259 3 0.014
lymphocyte proliferation GO:0046651 164 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
very long chain fatty acid metabolic process GO:0000038 8 0.014
response to growth factor GO:0070848 198 0.014
negative regulation of endopeptidase activity GO:0010951 44 0.014
innate immune response GO:0045087 157 0.014
monocarboxylic acid catabolic process GO:0072329 27 0.014
glycoprotein biosynthetic process GO:0009101 89 0.014
anatomical structure homeostasis GO:0060249 145 0.014
energy derivation by oxidation of organic compounds GO:0015980 77 0.014
response to insulin GO:0032868 100 0.014
negative regulation of peptidase activity GO:0010466 46 0.014
nucleoside monophosphate catabolic process GO:0009125 59 0.014
nuclear transport GO:0051169 139 0.014
regulation of cellular response to stress GO:0080135 159 0.014
regulation of lipid metabolic process GO:0019216 118 0.014
protein oligomerization GO:0051259 67 0.013
membrane organization GO:0061024 245 0.013
response to decreased oxygen levels GO:0036293 59 0.013
inorganic anion transport GO:0015698 43 0.013
vitamin d3 metabolic process GO:0070640 3 0.013
cellular response to peptide GO:1901653 92 0.013
negative regulation of action potential GO:0045759 1 0.013
carbohydrate homeostasis GO:0033500 128 0.013
regulation of cell migration GO:0030334 219 0.013
positive regulation of ion transport GO:0043270 65 0.013
negative regulation of endothelial cell migration GO:0010596 4 0.013
divalent metal ion transport GO:0070838 172 0.013
glycosylation GO:0070085 62 0.013
positive regulation of hormone secretion GO:0046887 38 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
regulation of protein localization GO:0032880 231 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
epithelial cell proliferation GO:0050673 174 0.013
long chain fatty acid metabolic process GO:0001676 26 0.013
cholesterol metabolic process GO:0008203 56 0.013
protein targeting GO:0006605 143 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
xenobiotic transport GO:0042908 1 0.013
cellular response to insulin stimulus GO:0032869 78 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
regulation of lipid biosynthetic process GO:0046890 54 0.012
mapk cascade GO:0000165 281 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
regulation of inflammatory response GO:0050727 147 0.012
protein import GO:0017038 101 0.012
alcohol catabolic process GO:0046164 16 0.012
ras protein signal transduction GO:0007265 77 0.012
gland development GO:0048732 330 0.012
Zebrafish
cellular response to oxidative stress GO:0034599 76 0.012
porphyrin containing compound metabolic process GO:0006778 22 0.012
regulation of wound healing GO:0061041 40 0.012
atp catabolic process GO:0006200 55 0.012
response to radiation GO:0009314 165 0.012
regulation of membrane potential GO:0042391 192 0.012
muscle cell differentiation GO:0042692 261 0.012
positive regulation of steroid hormone secretion GO:2000833 2 0.012
regulation of cell growth GO:0001558 91 0.012
regulation of transferase activity GO:0051338 263 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
regulation of ion transport GO:0043269 215 0.012
peptidyl serine modification GO:0018209 83 0.012
cellular alcohol metabolic process GO:0044107 3 0.012
alpha amino acid catabolic process GO:1901606 18 0.012
organic hydroxy compound biosynthetic process GO:1901617 77 0.012
positive regulation of catecholamine secretion GO:0033605 2 0.012
negative regulation of immune system process GO:0002683 209 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
unsaturated fatty acid metabolic process GO:0033559 31 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
neurotransmitter transport GO:0006836 76 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
response to oxygen levels GO:0070482 62 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
cellular response to inorganic substance GO:0071241 37 0.011
cell junction organization GO:0034330 77 0.011
sterol homeostasis GO:0055092 45 0.011
endocytosis GO:0006897 168 0.011
response to iron ion GO:0010039 4 0.011
spermatid differentiation GO:0048515 115 0.011
macromolecule glycosylation GO:0043413 55 0.011
cell cell junction organization GO:0045216 72 0.011
response to steroid hormone GO:0048545 56 0.011
kidney development GO:0001822 213 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
activation of immune response GO:0002253 138 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
homeostasis of number of cells GO:0048872 210 0.011
zymogen activation GO:0031638 41 0.011
protein polymerization GO:0051258 57 0.011
regulation of organelle organization GO:0033043 289 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
secondary alcohol metabolic process GO:1902652 3 0.011
retina development in camera type eye GO:0060041 119 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
cellular protein catabolic process GO:0044257 155 0.011
glucose homeostasis GO:0042593 128 0.011
lipid catabolic process GO:0016042 69 0.011
lateral inhibition GO:0046331 1 0.011
icosanoid metabolic process GO:0006690 33 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regulation of mapk cascade GO:0043408 248 0.011
learning or memory GO:0007611 148 0.011
androgen biosynthetic process GO:0006702 4 0.011
protein import into nucleus GO:0006606 95 0.011
development of primary sexual characteristics GO:0045137 143 0.011
peptide transport GO:0015833 133 0.011
positive regulation of kinase activity GO:0033674 155 0.011
inflammatory response GO:0006954 244 0.011
thioester metabolic process GO:0035383 19 0.011
regulation of lipid transport GO:0032368 36 0.011
alpha amino acid biosynthetic process GO:1901607 15 0.011
regulation of secretion GO:0051046 274 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
regulation of cell projection organization GO:0031344 206 0.011
nuclear division GO:0000280 158 0.011
dibenzo p dioxin metabolic process GO:0018894 1 0.010
neuron death GO:0070997 154 0.010
cell junction assembly GO:0034329 52 0.010
peripheral nervous system development GO:0007422 53 0.010
myosin filament organization GO:0031033 3 0.010
positive regulation of growth GO:0045927 104 0.010
regulation of fibrinolysis GO:0051917 1 0.010
calcium ion transport GO:0006816 159 0.010
acetate ester transport GO:1901374 2 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
cellular ion homeostasis GO:0006873 165 0.010
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.010
myosin filament assembly GO:0031034 2 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
acyl coa metabolic process GO:0006637 19 0.010
dicarboxylic acid transport GO:0006835 29 0.010
regulation of cellular catabolic process GO:0031329 242 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
histamine uptake GO:0051615 1 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.010

Aldh8a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
lipid metabolism disorder DOID:3146 0 0.042
inherited metabolic disorder DOID:655 0 0.042
steroid inherited metabolic disorder DOID:1701 0 0.042
disease of metabolism DOID:0014667 0 0.042
disease of anatomical entity DOID:7 0 0.019
immune system disease DOID:2914 0 0.019
nervous system disease DOID:863 0 0.017
hematopoietic system disease DOID:74 0 0.016
congenital adrenal hyperplasia DOID:0050811 0 0.014
vascular disease DOID:178 0 0.011
cardiovascular system disease DOID:1287 0 0.011
sensory system disease DOID:0050155 0 0.011