Mus musculus

26 known processes

Fndc5

fibronectin type III domain containing 5

(Aliases: Pxp,1500001L03Rik,AI836596,PeP,MGC129464,MGC129465,C87088)

Fndc5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transmembrane transport GO:0098655 266 0.211
ion transmembrane transport GO:0034220 361 0.192
inorganic ion transmembrane transport GO:0098660 234 0.190
inorganic cation transmembrane transport GO:0098662 207 0.106
regulation of membrane potential GO:0042391 192 0.082
transmembrane transport GO:0055085 412 0.081
cellular amino acid metabolic process GO:0006520 103 0.081
cation transport GO:0006812 399 0.080
actin cytoskeleton organization GO:0030036 220 0.063
potassium ion transport GO:0006813 52 0.059
regulation of system process GO:0044057 200 0.059
cellular potassium ion transport GO:0071804 43 0.058
muscle tissue development GO:0060537 308 0.055
amine metabolic process GO:0009308 45 0.054
cellular amine metabolic process GO:0044106 44 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.048
regulation of transmembrane transport GO:0034762 128 0.047
cardiac muscle cell contraction GO:0086003 7 0.046
regulation of cellular component biogenesis GO:0044087 181 0.045
myosin filament assembly GO:0031034 2 0.045
cell adhesion GO:0007155 329 0.043
sodium ion transmembrane transport GO:0035725 49 0.043
regulation of ion transmembrane transporter activity GO:0032412 54 0.042
cellular ketone metabolic process GO:0042180 84 0.042
cation homeostasis GO:0055080 212 0.040
ventricular cardiac muscle cell action potential GO:0086005 4 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.039
membrane organization GO:0061024 245 0.039
purine nucleoside triphosphate metabolic process GO:0009144 226 0.039
striated muscle tissue development GO:0014706 293 0.038
synaptic transmission GO:0007268 329 0.035
cofactor metabolic process GO:0051186 80 0.035
ribonucleotide metabolic process GO:0009259 291 0.035
positive regulation of cellular amine metabolic process GO:0033240 5 0.034
regulation of ion transport GO:0043269 215 0.034
skeletal muscle organ development GO:0060538 163 0.033
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
muscle cell differentiation GO:0042692 261 0.032
epithelial tube morphogenesis GO:0060562 303 0.032
coenzyme metabolic process GO:0006732 52 0.032
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
organic anion transport GO:0015711 137 0.031
cellular homeostasis GO:0019725 240 0.031
potassium ion transmembrane transport GO:0071805 43 0.031
lipid biosynthetic process GO:0008610 179 0.031
macromolecule catabolic process GO:0009057 281 0.031
posttranscriptional regulation of gene expression GO:0010608 155 0.031
anion transport GO:0006820 177 0.031
protein catabolic process GO:0030163 221 0.030
neurotransmitter transport GO:0006836 76 0.030
carboxylic acid transport GO:0046942 100 0.030
cellular lipid metabolic process GO:0044255 323 0.030
cellular chemical homeostasis GO:0055082 215 0.029
plasma membrane organization GO:0007009 90 0.029
nucleotide metabolic process GO:0009117 332 0.029
divalent metal ion transport GO:0070838 172 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.029
positive regulation of protein phosphorylation GO:0001934 242 0.029
action potential GO:0001508 78 0.028
endomembrane system organization GO:0010256 147 0.028
purine ribonucleoside metabolic process GO:0046128 241 0.028
multicellular organismal signaling GO:0035637 91 0.028
aromatic compound catabolic process GO:0019439 286 0.028
ribonucleoside metabolic process GO:0009119 245 0.028
purine containing compound metabolic process GO:0072521 311 0.028
skeletal system development GO:0001501 356 0.028
nitrogen compound transport GO:0071705 271 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
organophosphate catabolic process GO:0046434 232 0.027
cellular response to lipid GO:0071396 145 0.027
regulation of apoptotic signaling pathway GO:2001233 197 0.027
developmental maturation GO:0021700 193 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.026
striated muscle myosin thick filament assembly GO:0071688 1 0.026
cardiac muscle contraction GO:0060048 32 0.026
potassium ion homeostasis GO:0055075 4 0.026
regulation of neurotransmitter levels GO:0001505 87 0.026
protein localization to membrane GO:0072657 108 0.026
sensory organ morphogenesis GO:0090596 242 0.026
extracellular matrix organization GO:0030198 147 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
striated muscle cell development GO:0055002 125 0.025
regulation of actin filament based process GO:0032970 99 0.025
sequestering of calcium ion GO:0051208 18 0.025
actin filament based movement GO:0030048 23 0.025
cellular protein complex assembly GO:0043623 116 0.025
muscle cell development GO:0055001 133 0.025
regulation of metal ion transport GO:0010959 106 0.025
positive regulation of protein modification process GO:0031401 299 0.025
metal ion homeostasis GO:0055065 189 0.025
muscle contraction GO:0006936 101 0.024
single organismal cell cell adhesion GO:0016337 131 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
leukocyte differentiation GO:0002521 342 0.024
nucleoside metabolic process GO:0009116 246 0.024
spermatogenesis GO:0007283 284 0.024
organic hydroxy compound metabolic process GO:1901615 203 0.024
apoptotic signaling pathway GO:0097190 306 0.023
regulation of organelle organization GO:0033043 289 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.023
striated muscle contraction GO:0006941 45 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
fertilization GO:0009566 127 0.023
regulation of secretion by cell GO:1903530 249 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.023
mapk cascade GO:0000165 281 0.022
cellular protein catabolic process GO:0044257 155 0.022
cell type specific apoptotic process GO:0097285 268 0.022
fat cell differentiation GO:0045444 160 0.022
regulation of cell adhesion GO:0030155 154 0.022
actin mediated cell contraction GO:0070252 15 0.022
heart process GO:0003015 94 0.022
organelle assembly GO:0070925 177 0.022
positive regulation of nervous system development GO:0051962 221 0.022
divalent inorganic cation transport GO:0072511 178 0.022
embryonic organ morphogenesis GO:0048562 276 0.022
extracellular structure organization GO:0043062 148 0.021
rho protein signal transduction GO:0007266 32 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
renal sodium ion transport GO:0003096 2 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
regulation of sodium ion transmembrane transporter activity GO:2000649 9 0.021
actin filament polymerization GO:0030041 44 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
peptidyl amino acid modification GO:0018193 336 0.020
coenzyme biosynthetic process GO:0009108 23 0.020
regulation of cytoskeleton organization GO:0051493 122 0.020
regulation of myotube differentiation GO:0010830 62 0.020
single organism cell adhesion GO:0098602 156 0.020
male gamete generation GO:0048232 285 0.020
neuron neuron synaptic transmission GO:0007270 69 0.020
positive regulation of ion transport GO:0043270 65 0.020
neuronal action potential GO:0019228 54 0.020
ribonucleotide catabolic process GO:0009261 208 0.019
oxidation reduction process GO:0055114 342 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
regulation of kinase activity GO:0043549 249 0.019
sodium ion export from cell GO:0036376 1 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
organic acid transport GO:0015849 101 0.019
defecation GO:0030421 1 0.019
negative regulation of nervous system development GO:0051961 156 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
regulation of homeostatic process GO:0032844 182 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
protein maturation GO:0051604 176 0.019
muscle system process GO:0003012 141 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
regulation of cell projection organization GO:0031344 206 0.018
transmission of nerve impulse GO:0019226 76 0.018
regulation of ion transmembrane transport GO:0034765 119 0.018
dephosphorylation GO:0016311 129 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
negative regulation of cell development GO:0010721 169 0.018
neuron apoptotic process GO:0051402 142 0.018
positive regulation of cell death GO:0010942 224 0.018
regulation of neuron differentiation GO:0045664 281 0.018
regulation of muscle system process GO:0090257 80 0.018
nucleotide catabolic process GO:0009166 217 0.018
axon ensheathment GO:0008366 76 0.018
regulation of cell motility GO:2000145 236 0.018
regulation of protein kinase activity GO:0045859 232 0.018
regulation of cell cycle GO:0051726 281 0.017
regulation of secretion GO:0051046 274 0.017
synapse organization GO:0050808 125 0.017
protein polymerization GO:0051258 57 0.017
epithelial tube formation GO:0072175 130 0.017
positive regulation of cell development GO:0010720 237 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
regulation of heart contraction GO:0008016 77 0.017
regulation of sodium ion transmembrane transport GO:1902305 9 0.017
sequestering of metal ion GO:0051238 19 0.017
myosin filament organization GO:0031033 3 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
regulation of cellular catabolic process GO:0031329 242 0.016
regulation of hormone levels GO:0010817 211 0.016
purine containing compound catabolic process GO:0072523 213 0.016
positive regulation of potassium ion transport GO:0043268 3 0.016
regulation of hydrolase activity GO:0051336 246 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
myeloid cell differentiation GO:0030099 233 0.016
establishment of synaptic vesicle localization GO:0097480 57 0.016
myotube differentiation GO:0014902 105 0.016
negative regulation of immune system process GO:0002683 209 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
nucleoside monophosphate metabolic process GO:0009123 85 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
cell substrate adhesion GO:0031589 130 0.016
morphogenesis of a branching epithelium GO:0061138 193 0.016
ribonucleoside monophosphate metabolic process GO:0009161 80 0.016
regulation of transporter activity GO:0032409 57 0.016
central nervous system neuron differentiation GO:0021953 162 0.016
sodium ion transport GO:0006814 73 0.016
calcium ion transport GO:0006816 159 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
intracellular mrna localization GO:0008298 4 0.015
regulation of ion homeostasis GO:2000021 64 0.015
regulation of cell activation GO:0050865 289 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
organonitrogen compound catabolic process GO:1901565 264 0.015
axonogenesis GO:0007409 274 0.015
heterocycle catabolic process GO:0046700 280 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
bone development GO:0060348 120 0.015
renal system development GO:0072001 225 0.015
calcium ion transmembrane transport GO:0070588 85 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
cytoplasmic transport GO:0016482 234 0.015
kidney morphogenesis GO:0060993 83 0.015
positive regulation of organelle organization GO:0010638 128 0.015
neuron death GO:0070997 154 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
maintenance of location GO:0051235 89 0.015
tube formation GO:0035148 140 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
response to acid chemical GO:0001101 111 0.014
establishment of vesicle localization GO:0051650 81 0.014
muscle fiber development GO:0048747 76 0.014
ear morphogenesis GO:0042471 118 0.014
positive regulation of sodium ion transmembrane transport GO:1902307 4 0.014
lymphocyte differentiation GO:0030098 242 0.014
germ cell development GO:0007281 185 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
regulation of muscle contraction GO:0006937 49 0.014
heart contraction GO:0060047 93 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
regulation of mapk cascade GO:0043408 248 0.014
single fertilization GO:0007338 82 0.014
regulation of neuron death GO:1901214 134 0.014
adult locomotory behavior GO:0008344 91 0.014
cellular response to organic cyclic compound GO:0071407 87 0.014
nucleoside catabolic process GO:0009164 206 0.014
membrane depolarization GO:0051899 64 0.014
organelle localization GO:0051640 179 0.014
positive regulation of cellular component biogenesis GO:0044089 94 0.014
skeletal system morphogenesis GO:0048705 203 0.014
myelination GO:0042552 74 0.014
circulatory system process GO:0003013 197 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
organelle fission GO:0048285 170 0.014
dicarboxylic acid transport GO:0006835 29 0.014
cofactor biosynthetic process GO:0051188 41 0.014
vesicle localization GO:0051648 86 0.013
regulation of protein localization GO:0032880 231 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
regulation of intracellular transport GO:0032386 159 0.013
carbohydrate metabolic process GO:0005975 230 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
blood vessel morphogenesis GO:0048514 285 0.013
wnt signaling pathway GO:0016055 188 0.013
regulation of body fluid levels GO:0050878 162 0.013
cellular response to acid chemical GO:0071229 68 0.013
organ growth GO:0035265 117 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
ear development GO:0043583 200 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
neurotransmitter secretion GO:0007269 62 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
regulation of cell migration GO:0030334 219 0.013
potassium ion import GO:0010107 1 0.013
establishment of organelle localization GO:0051656 122 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
connective tissue development GO:0061448 179 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
digestive tract morphogenesis GO:0048546 147 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
rna interference GO:0016246 2 0.013
ossification GO:0001503 216 0.013
t cell activation GO:0042110 289 0.013
peptide transport GO:0015833 133 0.013
regulation of actin filament length GO:0030832 45 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
monosaccharide metabolic process GO:0005996 106 0.012
regulation of cell cycle process GO:0010564 160 0.012
neural tube development GO:0021915 160 0.012
mrna metabolic process GO:0016071 84 0.012
rna processing GO:0006396 105 0.012
synaptic vesicle transport GO:0048489 57 0.012
respiratory tube development GO:0030323 167 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
bone morphogenesis GO:0060349 78 0.012
regulation of transferase activity GO:0051338 263 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
regulation of striated muscle cell differentiation GO:0051153 81 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
female gamete generation GO:0007292 74 0.012
organophosphate ester transport GO:0015748 28 0.012
respiratory system development GO:0060541 190 0.012
calcium ion homeostasis GO:0055074 127 0.012
forebrain development GO:0030900 302 0.012
lipid localization GO:0010876 126 0.012
regulation of neuron projection development GO:0010975 169 0.012
response to radiation GO:0009314 165 0.012
protein localization to organelle GO:0033365 185 0.012
amide transport GO:0042886 138 0.012
protein processing GO:0016485 163 0.012
regulation of proteolysis GO:0030162 164 0.012
camera type eye development GO:0043010 266 0.012
establishment of protein localization to membrane GO:0090150 54 0.012
negative regulation of organelle organization GO:0010639 90 0.012
regulation of response to wounding GO:1903034 189 0.012
regulation of multi organism process GO:0043900 111 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
intracellular protein transport GO:0006886 204 0.011
mitotic cell cycle process GO:1903047 159 0.011
response to organic cyclic compound GO:0014070 198 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
defense response to other organism GO:0098542 197 0.011
protein ubiquitination GO:0016567 171 0.011
multi multicellular organism process GO:0044706 109 0.011
regionalization GO:0003002 337 0.011
actin polymerization or depolymerization GO:0008154 54 0.011
mitochondrion organization GO:0007005 134 0.011
actomyosin structure organization GO:0031032 56 0.011
negative regulation of molecular function GO:0044092 258 0.011
wound healing GO:0042060 157 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
response to organonitrogen compound GO:0010243 246 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
meiotic cell cycle GO:0051321 122 0.011
lung development GO:0030324 164 0.011
synapse assembly GO:0007416 56 0.011
multicellular organism growth GO:0035264 161 0.011
microtubule based process GO:0007017 236 0.011
compound eye development GO:0048749 1 0.011
atp metabolic process GO:0046034 75 0.011
stem cell differentiation GO:0048863 268 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
lateral inhibition GO:0046331 1 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
response to growth factor GO:0070848 198 0.011
monovalent inorganic cation homeostasis GO:0055067 33 0.011
development of primary sexual characteristics GO:0045137 143 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
regulation of ras gtpase activity GO:0032318 88 0.011
nucleocytoplasmic transport GO:0006913 139 0.010
rac protein signal transduction GO:0016601 13 0.010
protein targeting GO:0006605 143 0.010
gland development GO:0048732 330 0.010
fast calcium ion dependent exocytosis of neurotransmitter GO:0098746 1 0.010
response to oxidative stress GO:0006979 123 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
protein homooligomerization GO:0051260 43 0.010
pharynx development GO:0060465 1 0.010
negative regulation of protein metabolic process GO:0051248 282 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010
positive regulation of cytoskeleton organization GO:0051495 49 0.010
ribonucleoside monophosphate catabolic process GO:0009158 57 0.010
kidney development GO:0001822 213 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
tube closure GO:0060606 91 0.010
regulation of ovulation GO:0060278 3 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
homeostasis of number of cells GO:0048872 210 0.010

Fndc5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.034
disease of anatomical entity DOID:7 0 0.034
musculoskeletal system disease DOID:17 0 0.034
muscle tissue disease DOID:66 0 0.034
nervous system disease DOID:863 0 0.029
central nervous system disease DOID:331 0 0.028
cardiovascular system disease DOID:1287 0 0.026
myopathy DOID:423 0 0.014
brain disease DOID:936 0 0.014
heart disease DOID:114 0 0.013
cardiomyopathy DOID:0050700 0 0.013
intrinsic cardiomyopathy DOID:0060036 0 0.013
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011