Mus musculus

0 known processes

Dnajb2

DnaJ (Hsp40) homolog, subfamily B, member 2

(Aliases: MGC113758,2700059H22Rik,Dnajb10,Hsj1,mDj8)

Dnajb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.211
Human
response to endoplasmic reticulum stress GO:0034976 53 0.175
ubiquitin dependent protein catabolic process GO:0006511 129 0.153
Human
protein refolding GO:0042026 1 0.129
Human
inclusion body assembly GO:0070841 3 0.124
Human
apoptotic signaling pathway GO:0097190 306 0.117
modification dependent protein catabolic process GO:0019941 133 0.114
Human
positive regulation of cellular amine metabolic process GO:0033240 5 0.105
microtubule based process GO:0007017 236 0.104
cellular amino acid metabolic process GO:0006520 103 0.091
microtubule cytoskeleton organization GO:0000226 157 0.089
cellular response to topologically incorrect protein GO:0035967 25 0.087
regulation of cellular amino acid metabolic process GO:0006521 5 0.082
protein modification by small protein conjugation or removal GO:0070647 207 0.081
Human
modification dependent macromolecule catabolic process GO:0043632 133 0.079
Human
cellular ketone metabolic process GO:0042180 84 0.079
regulation of cellular amine metabolic process GO:0033238 20 0.075
glycosyl compound catabolic process GO:1901658 206 0.072
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.070
protein catabolic process GO:0030163 221 0.068
Human
nucleobase containing small molecule metabolic process GO:0055086 352 0.068
intracellular protein transport GO:0006886 204 0.066
protein modification by small protein conjugation GO:0032446 187 0.060
Human
protein ubiquitination GO:0016567 171 0.056
Human
regulation of cellular ketone metabolic process GO:0010565 66 0.053
negative regulation of cellular component organization GO:0051129 194 0.053
Human
cellular amine metabolic process GO:0044106 44 0.052
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.050
Human
purine nucleotide metabolic process GO:0006163 302 0.050
establishment of vesicle localization GO:0051650 81 0.049
amine metabolic process GO:0009308 45 0.048
intrinsic apoptotic signaling pathway GO:0097193 132 0.047
ribonucleotide catabolic process GO:0009261 208 0.047
mitochondrion degradation GO:0000422 3 0.046
response to unfolded protein GO:0006986 21 0.046
cellular macromolecule catabolic process GO:0044265 206 0.046
Human
membrane organization GO:0061024 245 0.044
spermatogenesis GO:0007283 284 0.044
peptidyl amino acid modification GO:0018193 336 0.042
misfolded protein transport GO:0070843 1 0.042
ribonucleotide metabolic process GO:0009259 291 0.041
response to topologically incorrect protein GO:0035966 25 0.041
purine containing compound metabolic process GO:0072521 311 0.041
cytokine production GO:0001816 319 0.040
ribose phosphate metabolic process GO:0019693 291 0.040
organophosphate catabolic process GO:0046434 232 0.040
aromatic compound catabolic process GO:0019439 286 0.039
purine nucleoside catabolic process GO:0006152 205 0.039
macromolecule catabolic process GO:0009057 281 0.038
Human
exocytosis GO:0006887 121 0.038
negative regulation of protein metabolic process GO:0051248 282 0.037
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.037
Human
ribonucleoside triphosphate metabolic process GO:0009199 220 0.037
cellular protein complex assembly GO:0043623 116 0.037
protein folding GO:0006457 28 0.037
Human
protein localization to organelle GO:0033365 185 0.036
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.036
regulation of apoptotic signaling pathway GO:2001233 197 0.036
male gamete generation GO:0048232 285 0.035
reactive oxygen species metabolic process GO:0072593 84 0.035
purine nucleoside metabolic process GO:0042278 241 0.035
heterocycle catabolic process GO:0046700 280 0.034
cellular protein catabolic process GO:0044257 155 0.034
Human
positive regulation of cellular catabolic process GO:0031331 148 0.034
Human
regulation of cellular component biogenesis GO:0044087 181 0.034
Human
purine ribonucleoside metabolic process GO:0046128 241 0.034
regulation of interleukin 8 production GO:0032677 3 0.033
transmembrane transport GO:0055085 412 0.033
purine containing compound catabolic process GO:0072523 213 0.032
regulation of protein complex assembly GO:0043254 83 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.031
retrograde transport endosome to golgi GO:0042147 2 0.031
glycosyl compound metabolic process GO:1901657 246 0.030
camera type eye development GO:0043010 266 0.030
negative regulation of molecular function GO:0044092 258 0.029
protein localization to membrane GO:0072657 108 0.029
regulation of synaptic vesicle priming GO:0010807 4 0.029
organelle localization GO:0051640 179 0.029
negative regulation of apoptotic signaling pathway GO:2001234 104 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
regulation of vesicle mediated transport GO:0060627 139 0.028
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.028
cell type specific apoptotic process GO:0097285 268 0.028
plasma membrane organization GO:0007009 90 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
nucleoside metabolic process GO:0009116 246 0.028
regulation of cell projection organization GO:0031344 206 0.028
negative regulation of protein modification process GO:0031400 163 0.028
Human
proteasomal protein catabolic process GO:0010498 98 0.028
Human
establishment of organelle localization GO:0051656 122 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
synaptic transmission GO:0007268 329 0.027
immune effector process GO:0002252 321 0.027
interleukin 8 production GO:0032637 4 0.027
regulation of secretion GO:0051046 274 0.027
regulation of neuron projection development GO:0010975 169 0.027
nucleotide catabolic process GO:0009166 217 0.026
negative regulation of cytokine production GO:0001818 84 0.026
regulation of mitochondrial fission GO:0090140 3 0.025
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.025
nucleotide metabolic process GO:0009117 332 0.025
regulation of neuron apoptotic process GO:0043523 122 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
adult behavior GO:0030534 135 0.024
vesicle localization GO:0051648 86 0.024
regulation of neuron death GO:1901214 134 0.024
positive regulation of organelle organization GO:0010638 128 0.024
regulation of cytokine production GO:0001817 266 0.024
oocyte axis specification GO:0007309 2 0.023
neuron death GO:0070997 154 0.023
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.023
macromolecular complex disassembly GO:0032984 43 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.022
regulation of cell cycle GO:0051726 281 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
locomotory behavior GO:0007626 195 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
regulation of exocytosis GO:0017157 61 0.022
regulation of inclusion body assembly GO:0090083 1 0.021
Human
nucleoside triphosphate catabolic process GO:0009143 205 0.021
neurotransmitter transport GO:0006836 76 0.021
synaptic vesicle transport GO:0048489 57 0.021
cellular homeostasis GO:0019725 240 0.021
neuron apoptotic process GO:0051402 142 0.021
pole plasm assembly GO:0007315 2 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
regionalization GO:0003002 337 0.020
regulation of cell growth GO:0001558 91 0.020
Human
dna repair GO:0006281 107 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
intracellular mrna localization GO:0008298 4 0.020
endoplasmic reticulum unfolded protein response GO:0030968 19 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
inorganic ion transmembrane transport GO:0098660 234 0.019
cellular response to oxidative stress GO:0034599 76 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.019
muscle cell differentiation GO:0042692 261 0.019
regulation of secretion by cell GO:1903530 249 0.019
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.019
synaptic vesicle priming GO:0016082 8 0.019
carbohydrate metabolic process GO:0005975 230 0.019
protein maturation GO:0051604 176 0.019
regulation of synaptic vesicle exocytosis GO:2000300 11 0.018
positive regulation of cell death GO:0010942 224 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
regulation of anatomical structure size GO:0090066 178 0.018
myeloid cell differentiation GO:0030099 233 0.018
innate immune response GO:0045087 157 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
organic acid biosynthetic process GO:0016053 86 0.018
actin cytoskeleton organization GO:0030036 220 0.018
Mouse
regulation of establishment of protein localization GO:0070201 181 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
regulation of protein catabolic process GO:0042176 108 0.018
Human
regulation of cellular catabolic process GO:0031329 242 0.017
Human
cellular response to dna damage stimulus GO:0006974 207 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
male genitalia morphogenesis GO:0048808 4 0.017
cellular protein complex disassembly GO:0043624 36 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.017
muscle tissue development GO:0060537 308 0.017
cation transport GO:0006812 399 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
positive regulation of proteolysis GO:0045862 85 0.017
Human
nucleoside monophosphate catabolic process GO:0009125 59 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
translation GO:0006412 93 0.017
microtubule based movement GO:0007018 84 0.017
regulation of cellular component size GO:0032535 121 0.017
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.016
regulation of organelle organization GO:0033043 289 0.016
negative regulation of cell development GO:0010721 169 0.016
germ cell development GO:0007281 185 0.016
gtp catabolic process GO:0006184 143 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
microtubule based transport GO:0010970 50 0.016
maternal determination of anterior posterior axis embryo GO:0008358 2 0.016
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.016
response to organonitrogen compound GO:0010243 246 0.016
positive regulation of cell development GO:0010720 237 0.016
response to oxidative stress GO:0006979 123 0.016
nucleoside monophosphate metabolic process GO:0009123 85 0.016
oocyte construction GO:0007308 2 0.016
histone modification GO:0016570 159 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.015
substantia nigra development GO:0021762 2 0.015
striated muscle tissue development GO:0014706 293 0.015
nucleoside catabolic process GO:0009164 206 0.015
myeloid cell homeostasis GO:0002262 114 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
homeostasis of number of cells GO:0048872 210 0.015
purine nucleoside monophosphate catabolic process GO:0009128 58 0.015
regulation of cellular response to stress GO:0080135 159 0.015
fat cell differentiation GO:0045444 160 0.015
developmental maturation GO:0021700 193 0.014
endodermal cell fate specification GO:0001714 4 0.014
axonogenesis GO:0007409 274 0.014
response to oxygen levels GO:0070482 62 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
localization within membrane GO:0051668 4 0.014
positive regulation of protein modification process GO:0031401 299 0.014
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
regulation of neurotransmitter levels GO:0001505 87 0.014
endomembrane system organization GO:0010256 147 0.014
multicellular organism growth GO:0035264 161 0.014
response to inorganic substance GO:0010035 96 0.014
establishment of synaptic vesicle localization GO:0097480 57 0.014
positive regulation of cytoskeleton organization GO:0051495 49 0.014
protein localization to plasma membrane GO:0072659 57 0.014
cytoskeleton dependent intracellular transport GO:0030705 50 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
neuron neuron synaptic transmission GO:0007270 69 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
transmission of nerve impulse GO:0019226 76 0.013
negative regulation of cell cycle GO:0045786 123 0.013
sequestering of calcium ion GO:0051208 18 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
response to extracellular stimulus GO:0009991 127 0.013
dna metabolic process GO:0006259 303 0.013
divalent inorganic cation transport GO:0072511 178 0.013
cell maturation GO:0048469 127 0.013
regulation of hydrolase activity GO:0051336 246 0.013
cellular response to nutrient levels GO:0031669 64 0.013
ossification GO:0001503 216 0.013
spermatid differentiation GO:0048515 115 0.013
neuronal action potential GO:0019228 54 0.013
regulation of fat cell differentiation GO:0045598 81 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
endocytosis GO:0006897 168 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
response to reactive oxygen species GO:0000302 56 0.013
mitotic cell cycle GO:0000278 195 0.013
dephosphorylation GO:0016311 129 0.013
regulation of binding GO:0051098 111 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
pharynx development GO:0060465 1 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
atp catabolic process GO:0006200 55 0.013
cellular chemical homeostasis GO:0055082 215 0.013
neurotransmitter secretion GO:0007269 62 0.013
protein hydroxylation GO:0018126 4 0.013
regulation of transferase activity GO:0051338 263 0.013
positive regulation of secretion by cell GO:1903532 114 0.013
intracellular receptor signaling pathway GO:0030522 74 0.013
metencephalon development GO:0022037 89 0.012
regulation of intracellular transport GO:0032386 159 0.012
divalent metal ion transport GO:0070838 172 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
positive regulation of protein complex assembly GO:0031334 45 0.012
synaptic vesicle localization GO:0097479 59 0.012
wnt signaling pathway GO:0016055 188 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
protein acylation GO:0043543 64 0.012
regulation of kinase activity GO:0043549 249 0.012
nitrogen compound transport GO:0071705 271 0.012
organelle disassembly GO:1903008 2 0.012
cilium morphogenesis GO:0060271 102 0.012
negative regulation of organelle organization GO:0010639 90 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
mitotic cell cycle process GO:1903047 159 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
inflammatory response GO:0006954 244 0.012
mitochondrion organization GO:0007005 134 0.012
rhythmic process GO:0048511 174 0.012
regulation of protein localization GO:0032880 231 0.012
monocarboxylic acid biosynthetic process GO:0072330 61 0.012
regulation of multi organism process GO:0043900 111 0.012
sequestering of metal ion GO:0051238 19 0.012
cerebellum development GO:0021549 77 0.012
cyclic nucleotide metabolic process GO:0009187 59 0.012
neuromuscular process GO:0050905 99 0.012
negative regulation of neuron death GO:1901215 98 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
positive regulation of neuron apoptotic process GO:0043525 25 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
vesicle organization GO:0016050 60 0.011
protein import GO:0017038 101 0.011
cytoplasmic transport GO:0016482 234 0.011
sensory perception GO:0007600 245 0.011
multicellular organismal signaling GO:0035637 91 0.011
negative regulation of kinase activity GO:0033673 81 0.011
peptidyl proline hydroxylation GO:0019511 3 0.011
regulation of polyamine transmembrane transport GO:1902267 5 0.011
skeletal muscle organ development GO:0060538 163 0.011
er nucleus signaling pathway GO:0006984 27 0.011
regulation of cell cycle process GO:0010564 160 0.011
response to acid chemical GO:0001101 111 0.011
regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway GO:1902235 11 0.011
response to epidermal growth factor GO:0070849 4 0.011
cellular ion homeostasis GO:0006873 165 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
regulation of synaptic vesicle transport GO:1902803 13 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.011
protein depolymerization GO:0051261 34 0.011
regulation of cell motility GO:2000145 236 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
leukocyte differentiation GO:0002521 342 0.011
anatomical structure homeostasis GO:0060249 145 0.011
sensory system development GO:0048880 3 0.011
male anatomical structure morphogenesis GO:0090598 4 0.011
regulation of protein kinase activity GO:0045859 232 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
regulation of membrane potential GO:0042391 192 0.011
organelle assembly GO:0070925 177 0.011
oocyte anterior posterior axis specification GO:0007314 2 0.011
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.011
leukocyte mediated immunity GO:0002443 174 0.011
rab protein signal transduction GO:0032482 1 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
microtubule severing GO:0051013 5 0.010
cation homeostasis GO:0055080 212 0.010
negative regulation of defense response GO:0031348 77 0.010
alpha amino acid metabolic process GO:1901605 59 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.010
atp metabolic process GO:0046034 75 0.010
organic hydroxy compound transport GO:0015850 93 0.010
ion transmembrane transport GO:0034220 361 0.010
lymphocyte differentiation GO:0030098 242 0.010
negative regulation of immune system process GO:0002683 209 0.010
positive regulation of growth GO:0045927 104 0.010
skin development GO:0043588 220 0.010
anion transport GO:0006820 177 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
establishment or maintenance of cell polarity GO:0007163 86 0.010
mapk cascade GO:0000165 281 0.010
regulation of cell activation GO:0050865 289 0.010
positive regulation of interleukin 8 production GO:0032757 2 0.010
regulation of defense response to bacterium GO:1900424 3 0.010
actin filament polymerization GO:0030041 44 0.010
nucleotide biosynthetic process GO:0009165 78 0.010

Dnajb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
cardiovascular system disease DOID:1287 0 0.021
heart disease DOID:114 0 0.019
nervous system disease DOID:863 0 0.019
muscular disease DOID:0080000 0 0.016
musculoskeletal system disease DOID:17 0 0.016
muscle tissue disease DOID:66 0 0.016
immune system disease DOID:2914 0 0.015
hematopoietic system disease DOID:74 0 0.015
myopathy DOID:423 0 0.014
cardiomyopathy DOID:0050700 0 0.014
intrinsic cardiomyopathy DOID:0060036 0 0.014
neuropathy DOID:870 0 0.011