Mus musculus

42 known processes

Xrcc1

X-ray repair complementing defective repair in Chinese hamster cells 1

(Aliases: MGC102556,Xrcc-1)

Xrcc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ribonucleotide catabolic process GO:0009261 208 0.182
regulation of antimicrobial humoral response GO:0002759 3 0.102
nucleoside metabolic process GO:0009116 246 0.095
nucleobase containing small molecule metabolic process GO:0055086 352 0.089
chromatin organization GO:0006325 206 0.087
heterocycle catabolic process GO:0046700 280 0.077
organic cyclic compound catabolic process GO:1901361 295 0.073
ras protein signal transduction GO:0007265 77 0.073
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.070
aromatic compound catabolic process GO:0019439 286 0.068
carbohydrate derivative catabolic process GO:1901136 231 0.068
dna metabolic process GO:0006259 303 0.067
cellular nitrogen compound catabolic process GO:0044270 280 0.067
negative regulation of cell proliferation GO:0008285 296 0.066
ribonucleotide metabolic process GO:0009259 291 0.064
organonitrogen compound catabolic process GO:1901565 264 0.063
cellular response to dna damage stimulus GO:0006974 207 0.060
glycosyl compound metabolic process GO:1901657 246 0.060
rna interference GO:0016246 2 0.056
purine nucleoside triphosphate metabolic process GO:0009144 226 0.054
antimicrobial peptide production GO:0002775 2 0.052
cellular amino acid metabolic process GO:0006520 103 0.050
purine nucleoside metabolic process GO:0042278 241 0.050
purine nucleoside catabolic process GO:0006152 205 0.048
digestive tract development GO:0048565 190 0.046
purine ribonucleoside catabolic process GO:0046130 205 0.045
ribonucleoside catabolic process GO:0042454 206 0.044
immune effector process GO:0002252 321 0.044
regulation of multi organism process GO:0043900 111 0.044
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.043
ribonucleoside triphosphate metabolic process GO:0009199 220 0.042
purine ribonucleoside metabolic process GO:0046128 241 0.042
multi multicellular organism process GO:0044706 109 0.039
nuclear division GO:0000280 158 0.038
organophosphate catabolic process GO:0046434 232 0.037
small gtpase mediated signal transduction GO:0007264 97 0.036
nucleotide metabolic process GO:0009117 332 0.036
nucleotide catabolic process GO:0009166 217 0.035
nucleoside phosphate catabolic process GO:1901292 222 0.035
response to acid chemical GO:0001101 111 0.034
purine nucleoside triphosphate catabolic process GO:0009146 203 0.034
regulation of cell cycle GO:0051726 281 0.034
purine nucleoside monophosphate catabolic process GO:0009128 58 0.034
purine ribonucleotide catabolic process GO:0009154 208 0.034
nucleoside triphosphate catabolic process GO:0009143 205 0.033
nucleoside catabolic process GO:0009164 206 0.033
endocytosis GO:0006897 168 0.032
gene silencing GO:0016458 38 0.032
regulation of cell cycle process GO:0010564 160 0.032
embryonic placenta development GO:0001892 98 0.032
dna repair GO:0006281 107 0.031
negative regulation of multi organism process GO:0043901 68 0.031
nucleoside monophosphate metabolic process GO:0009123 85 0.031
embryonic organ morphogenesis GO:0048562 276 0.031
epidermis development GO:0008544 187 0.030
glycosyl compound catabolic process GO:1901658 206 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
atp catabolic process GO:0006200 55 0.029
innate immune response GO:0045087 157 0.029
digestive system development GO:0055123 200 0.029
camera type eye development GO:0043010 266 0.028
purine containing compound metabolic process GO:0072521 311 0.028
hatching GO:0035188 4 0.028
chromatin modification GO:0016568 187 0.028
posttranscriptional gene silencing by rna GO:0035194 10 0.027
macromolecule catabolic process GO:0009057 281 0.027
gene silencing by mirna GO:0035195 10 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
metal ion homeostasis GO:0055065 189 0.027
purine nucleotide catabolic process GO:0006195 211 0.026
stem cell development GO:0048864 219 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
cytokine production GO:0001816 319 0.025
maintenance of apical basal cell polarity GO:0035090 3 0.025
regulation of cell cycle phase transition GO:1901987 77 0.025
viral transcription GO:0019083 3 0.025
regulation of hydrolase activity GO:0051336 246 0.025
stem cell differentiation GO:0048863 268 0.024
purine containing compound catabolic process GO:0072523 213 0.024
positive regulation of cell death GO:0010942 224 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
cellular response to lipid GO:0071396 145 0.024
organism emergence from protective structure GO:0071684 4 0.024
negative regulation of molecular function GO:0044092 258 0.023
cellular amine metabolic process GO:0044106 44 0.023
skeletal system development GO:0001501 356 0.023
multicellular organismal aging GO:0010259 24 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
covalent chromatin modification GO:0016569 163 0.023
gene silencing by rna GO:0031047 19 0.023
cellular ketone metabolic process GO:0042180 84 0.022
protein localization to cell junction GO:1902414 3 0.022
microtubule based process GO:0007017 236 0.022
translation GO:0006412 93 0.021
response to lipopolysaccharide GO:0032496 128 0.021
regulation of antimicrobial peptide production GO:0002784 1 0.020
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
protein catabolic process GO:0030163 221 0.020
motor neuron migration GO:0097475 4 0.020
mitotic cell cycle GO:0000278 195 0.020
protein targeting GO:0006605 143 0.020
proteasomal protein catabolic process GO:0010498 98 0.020
regulation of response to biotic stimulus GO:0002831 38 0.019
modification dependent macromolecule catabolic process GO:0043632 133 0.019
b cell activation GO:0042113 161 0.019
sensory organ morphogenesis GO:0090596 242 0.019
regulation of mrna splicing via spliceosome GO:0048024 32 0.019
antimicrobial peptide biosynthetic process GO:0002777 2 0.019
male gamete generation GO:0048232 285 0.018
regulation of binding GO:0051098 111 0.018
cellular protein catabolic process GO:0044257 155 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
intracellular receptor signaling pathway GO:0030522 74 0.018
gland development GO:0048732 330 0.018
interspecies interaction between organisms GO:0044419 83 0.018
regulation of cytokine production GO:0001817 266 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
rna processing GO:0006396 105 0.018
nucleotide excision repair GO:0006289 13 0.018
protein localization to adherens junction GO:0071896 2 0.018
regulation of ras protein signal transduction GO:0046578 114 0.018
calcium ion homeostasis GO:0055074 127 0.017
single organism nuclear import GO:1902593 95 0.017
cell cycle checkpoint GO:0000075 47 0.017
regulation of organelle organization GO:0033043 289 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.017
response to transforming growth factor beta GO:0071559 88 0.017
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.017
intracellular protein transport GO:0006886 204 0.017
meiotic nuclear division GO:0007126 115 0.017
sensory perception GO:0007600 245 0.017
viral gene expression GO:0019080 3 0.017
skin development GO:0043588 220 0.017
positive regulation of nucleotide catabolic process GO:0030813 88 0.017
regulation of cellular ketone metabolic process GO:0010565 66 0.016
response to organic cyclic compound GO:0014070 198 0.016
demethylation GO:0070988 23 0.016
gonad development GO:0008406 141 0.016
organelle fission GO:0048285 170 0.016
nucleoside monophosphate catabolic process GO:0009125 59 0.016
nuclear import GO:0051170 95 0.016
chemotaxis GO:0006935 247 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
regulation of cell motility GO:2000145 236 0.016
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.016
response to radiation GO:0009314 165 0.015
striated muscle tissue development GO:0014706 293 0.015
amine metabolic process GO:0009308 45 0.015
histone deubiquitination GO:0016578 2 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
metencephalon development GO:0022037 89 0.015
protein localization to organelle GO:0033365 185 0.015
epithelial tube formation GO:0072175 130 0.015
development of primary sexual characteristics GO:0045137 143 0.015
cation homeostasis GO:0055080 212 0.015
locomotory behavior GO:0007626 195 0.015
atp metabolic process GO:0046034 75 0.015
nuclear transport GO:0051169 139 0.015
positive regulation of gtpase activity GO:0043547 85 0.015
neuron death GO:0070997 154 0.015
cellular amide metabolic process GO:0043603 58 0.015
tube closure GO:0060606 91 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
cellular response to organic cyclic compound GO:0071407 87 0.014
protein localization to nucleus GO:0034504 121 0.014
spermatogenesis GO:0007283 284 0.014
production of molecular mediator of immune response GO:0002440 103 0.014
regulation of protein kinase activity GO:0045859 232 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
posttranscriptional gene silencing GO:0016441 10 0.014
peptide metabolic process GO:0006518 46 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
dna templated transcription initiation GO:0006352 13 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
digestive tract morphogenesis GO:0048546 147 0.014
cell adhesion GO:0007155 329 0.014
response to temperature stimulus GO:0009266 55 0.014
regulation of cellular amino acid metabolic process GO:0006521 5 0.014
dna recombination GO:0006310 92 0.014
connective tissue development GO:0061448 179 0.014
hindbrain development GO:0030902 128 0.013
protein oligomerization GO:0051259 67 0.013
receptor mediated endocytosis GO:0006898 51 0.013
cellular homeostasis GO:0019725 240 0.013
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.013
blastocyst development GO:0001824 80 0.013
embryonic digestive tract development GO:0048566 27 0.013
regulation of dna binding GO:0051101 39 0.013
muscle cell differentiation GO:0042692 261 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
pharynx development GO:0060465 1 0.013
viral life cycle GO:0019058 36 0.013
positive regulation of protein modification process GO:0031401 299 0.013
lipid homeostasis GO:0055088 63 0.013
neural tube development GO:0021915 160 0.013
histone lysine demethylation GO:0070076 13 0.013
astrocyte cell migration GO:0043615 3 0.013
homeostasis of number of cells GO:0048872 210 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
apoptotic signaling pathway GO:0097190 306 0.013
protein ubiquitination GO:0016567 171 0.013
fat cell differentiation GO:0045444 160 0.013
cellular response to acid chemical GO:0071229 68 0.013
oocyte construction GO:0007308 2 0.013
epithelial cell development GO:0002064 159 0.013
response to light stimulus GO:0009416 135 0.012
cellular ion homeostasis GO:0006873 165 0.012
appendage development GO:0048736 166 0.012
negative regulation of cell cycle process GO:0010948 69 0.012
viral process GO:0016032 41 0.012
response to oxidative stress GO:0006979 123 0.012
establishment of tissue polarity GO:0007164 28 0.012
skeletal muscle organ development GO:0060538 163 0.012
negative regulation of cell cycle phase transition GO:1901988 48 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
protein processing GO:0016485 163 0.012
dna replication GO:0006260 52 0.012
peptide transport GO:0015833 133 0.012
histone modification GO:0016570 159 0.012
muscle tissue development GO:0060537 308 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
cytoplasmic transport GO:0016482 234 0.012
rna splicing via transesterification reactions GO:0000375 43 0.012
positive regulation of microtubule polymerization or depolymerization GO:0031112 3 0.012
dna biosynthetic process GO:0071897 22 0.012
learning or memory GO:0007611 148 0.012
establishment of planar polarity GO:0001736 28 0.012
regulation of protein catabolic process GO:0042176 108 0.012
vitamin d receptor signaling pathway GO:0070561 2 0.012
mrna processing GO:0006397 63 0.012
mammary gland epithelium development GO:0061180 65 0.012
negative regulation of cytokine production GO:0001818 84 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.011
stem cell maintenance GO:0019827 130 0.011
inner ear receptor cell differentiation GO:0060113 61 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
intermediate filament based process GO:0045103 27 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.011
regionalization GO:0003002 337 0.011
regulation of tumor necrosis factor production GO:0032680 49 0.011
protein maturation GO:0051604 176 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
cognition GO:0050890 149 0.011
tube formation GO:0035148 140 0.011
wound healing GO:0042060 157 0.011
multicellular organism growth GO:0035264 161 0.011
limb development GO:0060173 166 0.011
maintenance of location GO:0051235 89 0.011
negative regulation of mitotic cell cycle GO:0045930 58 0.011
regulation of cellular amine metabolic process GO:0033238 20 0.011
defense response to other organism GO:0098542 197 0.011
negative regulation of binding GO:0051100 39 0.011
regulation of proteolysis GO:0030162 164 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
germ cell development GO:0007281 185 0.011
auditory receptor cell differentiation GO:0042491 37 0.011
urogenital system development GO:0001655 261 0.011
regulation of viral transcription GO:0046782 3 0.010
regulation of response to alcohol GO:1901419 2 0.010
leukocyte differentiation GO:0002521 342 0.010
gastrulation GO:0007369 116 0.010
mitotic cell cycle process GO:1903047 159 0.010
hematopoietic stem cell proliferation GO:0071425 13 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.010
vesicle localization GO:0051648 86 0.010
primary neural tube formation GO:0014020 95 0.010
cardiocyte differentiation GO:0035051 87 0.010
chromatin remodeling GO:0006338 32 0.010
positive regulation of cytokine production GO:0001819 174 0.010
regulation of neuron death GO:1901214 134 0.010
negative regulation of protein processing GO:0010955 79 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
regulation of hormone levels GO:0010817 211 0.010
regulation of chromosome organization GO:0033044 83 0.010

Xrcc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.039
central nervous system disease DOID:331 0 0.021
neurodegenerative disease DOID:1289 0 0.018
disease of cellular proliferation DOID:14566 0 0.016