Mus musculus

102 known processes

Xrcc2

X-ray repair complementing defective repair in Chinese hamster cells 2

(Aliases: RecA,4921524O04Rik,RAD51,8030409M04Rik)

Xrcc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 107 0.192
dna metabolic process GO:0006259 303 0.182
cellular response to dna damage stimulus GO:0006974 207 0.119
response to radiation GO:0009314 165 0.103
dna recombination GO:0006310 92 0.103
meiotic nuclear division GO:0007126 115 0.092
mitotic cell cycle GO:0000278 195 0.087
chromatin organization GO:0006325 206 0.085
maintenance of location GO:0051235 89 0.071
meiotic cell cycle GO:0051321 122 0.069
nuclear division GO:0000280 158 0.063
macromolecule methylation GO:0043414 120 0.062
double strand break repair via homologous recombination GO:0000724 21 0.061
lymphocyte differentiation GO:0030098 242 0.054
mitotic cell cycle process GO:1903047 159 0.048
organelle fission GO:0048285 170 0.048
methylation GO:0032259 134 0.046
regulation of cell cycle GO:0051726 281 0.045
male gamete generation GO:0048232 285 0.043
chromatin modification GO:0016568 187 0.042
establishment or maintenance of cell polarity GO:0007163 86 0.042
microtubule cytoskeleton organization GO:0000226 157 0.041
multicellular organismal signaling GO:0035637 91 0.041
sensory organ morphogenesis GO:0090596 242 0.040
transmembrane transport GO:0055085 412 0.040
regulation of cell cycle process GO:0010564 160 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
divalent inorganic cation transport GO:0072511 178 0.035
t cell activation GO:0042110 289 0.035
purine nucleotide metabolic process GO:0006163 302 0.034
microtubule based process GO:0007017 236 0.034
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.034
protein maturation GO:0051604 176 0.034
cell type specific apoptotic process GO:0097285 268 0.033
striated muscle tissue development GO:0014706 293 0.033
meiotic cell cycle process GO:1903046 77 0.033
regulation of cell activation GO:0050865 289 0.033
transmission of nerve impulse GO:0019226 76 0.032
cellular amino acid metabolic process GO:0006520 103 0.032
telomere maintenance GO:0000723 19 0.032
negative regulation of cell cycle GO:0045786 123 0.032
cellular ketone metabolic process GO:0042180 84 0.032
double strand break repair GO:0006302 48 0.032
histone modification GO:0016570 159 0.032
stem cell differentiation GO:0048863 268 0.031
blood vessel morphogenesis GO:0048514 285 0.030
muscle tissue development GO:0060537 308 0.030
organelle assembly GO:0070925 177 0.030
sensory perception GO:0007600 245 0.029
asymmetric stem cell division GO:0098722 3 0.029
gland development GO:0048732 330 0.029
stem cell maintenance GO:0019827 130 0.028
protein alkylation GO:0008213 81 0.028
mapk cascade GO:0000165 281 0.028
leukocyte differentiation GO:0002521 342 0.028
regulation of organelle organization GO:0033043 289 0.028
male meiosis GO:0007140 37 0.027
activation of mapk activity involved in innate immune response GO:0035419 2 0.027
regulation of homeostatic process GO:0032844 182 0.027
meiosis i GO:0007127 60 0.027
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.027
germ cell development GO:0007281 185 0.027
histone methylation GO:0016571 71 0.027
recombinational repair GO:0000725 21 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
cytoplasmic transport GO:0016482 234 0.026
spermatogenesis GO:0007283 284 0.026
myeloid cell homeostasis GO:0002262 114 0.025
regulation of cellular response to stress GO:0080135 159 0.025
apoptotic signaling pathway GO:0097190 306 0.025
regulation of t cell activation GO:0050863 170 0.025
male meiosis i GO:0007141 16 0.024
regulation of kinase activity GO:0043549 249 0.024
purine containing compound metabolic process GO:0072521 311 0.024
response to peptide GO:1901652 136 0.024
locomotory behavior GO:0007626 195 0.024
dna conformation change GO:0071103 37 0.024
ribonucleotide metabolic process GO:0009259 291 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
chromosome segregation GO:0007059 48 0.023
calcium ion transport GO:0006816 159 0.023
synapsis GO:0007129 34 0.023
covalent chromatin modification GO:0016569 163 0.023
regulation of mitotic cell cycle phase transition GO:1901990 73 0.023
establishment of spindle localization GO:0051293 19 0.023
epithelial tube morphogenesis GO:0060562 303 0.023
divalent metal ion transport GO:0070838 172 0.023
myelination GO:0042552 74 0.023
cellular amine metabolic process GO:0044106 44 0.023
regulation of mitotic cell cycle GO:0007346 126 0.022
development of primary sexual characteristics GO:0045137 143 0.022
sequestering of metal ion GO:0051238 19 0.022
stem cell development GO:0048864 219 0.022
multicellular organism growth GO:0035264 161 0.022
organelle localization GO:0051640 179 0.022
cell division GO:0051301 120 0.021
homeostasis of number of cells GO:0048872 210 0.021
response to light stimulus GO:0009416 135 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
negative regulation of homeostatic process GO:0032845 71 0.021
cation transport GO:0006812 399 0.021
myeloid cell differentiation GO:0030099 233 0.020
neuronal action potential GO:0019228 54 0.020
cellular homeostasis GO:0019725 240 0.020
fertilization GO:0009566 127 0.020
regulation of cell cycle phase transition GO:1901987 77 0.020
sensory perception of sound GO:0007605 97 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.019
response to ionizing radiation GO:0010212 42 0.019
b cell activation GO:0042113 161 0.019
skeletal system development GO:0001501 356 0.019
gonad development GO:0008406 141 0.019
adaptive immune response GO:0002250 155 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.019
cation homeostasis GO:0055080 212 0.019
synaptic transmission GO:0007268 329 0.019
regulation of anatomical structure size GO:0090066 178 0.019
protein processing GO:0016485 163 0.018
axonogenesis GO:0007409 274 0.018
regulation of proteolysis GO:0030162 164 0.018
rhodopsin mediated signaling pathway GO:0016056 4 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
regulation of neuron differentiation GO:0045664 281 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
sequestering of calcium ion GO:0051208 18 0.018
negative regulation of cell development GO:0010721 169 0.018
meiotic dna repair synthesis GO:0000711 4 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
smoothened signaling pathway GO:0007224 105 0.017
regulation of multi organism process GO:0043900 111 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
regulation of protein kinase activity GO:0045859 232 0.017
ensheathment of neurons GO:0007272 76 0.017
amine metabolic process GO:0009308 45 0.017
regulation of lymphocyte mediated immunity GO:0002706 84 0.017
maternal determination of anterior posterior axis embryo GO:0008358 2 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
positive regulation of transferase activity GO:0051347 167 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.016
spindle localization GO:0051653 22 0.016
chemotaxis GO:0006935 247 0.016
gliogenesis GO:0042063 141 0.016
leukocyte mediated immunity GO:0002443 174 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
regulation of secretion GO:0051046 274 0.016
regulation of ion transport GO:0043269 215 0.016
axon ensheathment GO:0008366 76 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
negative regulation of nervous system development GO:0051961 156 0.016
alpha beta t cell differentiation GO:0046632 69 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
regulation of chromosome organization GO:0033044 83 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
cellular response to peptide hormone stimulus GO:0071375 92 0.016
nucleotide metabolic process GO:0009117 332 0.015
centrosome cycle GO:0007098 23 0.015
response to insulin GO:0032868 100 0.015
positive regulation of t cell activation GO:0050870 101 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
b cell differentiation GO:0030183 78 0.015
forebrain development GO:0030900 302 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
respiratory system development GO:0060541 190 0.015
regulation of leukocyte mediated immunity GO:0002703 104 0.015
anatomical structure homeostasis GO:0060249 145 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
asymmetric neuroblast division GO:0055059 1 0.015
negative regulation of mitotic cell cycle GO:0045930 58 0.015
spermatid development GO:0007286 108 0.015
macromolecule catabolic process GO:0009057 281 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.015
intracellular protein transport GO:0006886 204 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
regulation of lymphocyte differentiation GO:0045619 107 0.015
heterocycle catabolic process GO:0046700 280 0.014
regulation of cellular component size GO:0032535 121 0.014
response to peptide hormone GO:0043434 127 0.014
negative regulation of organelle organization GO:0010639 90 0.014
regulation of histone methylation GO:0031060 30 0.014
peptidyl amino acid modification GO:0018193 336 0.014
actin mediated cell contraction GO:0070252 15 0.014
response to lipopolysaccharide GO:0032496 128 0.014
negative regulation of cell cycle phase transition GO:1901988 48 0.014
leukocyte proliferation GO:0070661 172 0.014
developmental maturation GO:0021700 193 0.014
cell fate commitment GO:0045165 210 0.014
protein polymerization GO:0051258 57 0.014
visual perception GO:0007601 52 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
cell cell recognition GO:0009988 44 0.014
regulation of adaptive immune response GO:0002819 90 0.014
negative regulation of t cell activation GO:0050868 65 0.014
rhythmic process GO:0048511 174 0.014
immune effector process GO:0002252 321 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
sister chromatid segregation GO:0000819 20 0.014
positive regulation of protein modification process GO:0031401 299 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.013
response to organonitrogen compound GO:0010243 246 0.013
negative regulation of cell fate specification GO:0009996 4 0.013
cell cycle checkpoint GO:0000075 47 0.013
response to transforming growth factor beta GO:0071559 88 0.013
cellular response to abiotic stimulus GO:0071214 56 0.013
detection of light stimulus GO:0009583 25 0.013
digestive system development GO:0055123 200 0.013
mitotic sister chromatid segregation GO:0000070 14 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.013
regulation of alpha beta t cell activation GO:0046634 53 0.013
respiratory tube development GO:0030323 167 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
camera type eye development GO:0043010 266 0.013
glucose homeostasis GO:0042593 128 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
regulation of transmembrane transport GO:0034762 128 0.013
rna splicing GO:0008380 54 0.013
neuroblast differentiation GO:0014016 2 0.013
hepaticobiliary system development GO:0061008 67 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
regulation of secretion by cell GO:1903530 249 0.013
bone development GO:0060348 120 0.013
skeletal system morphogenesis GO:0048705 203 0.012
mitochondrion organization GO:0007005 134 0.012
cation transmembrane transport GO:0098655 266 0.012
regulation of protein processing GO:0070613 96 0.012
ear development GO:0043583 200 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
establishment of spindle orientation GO:0051294 15 0.012
alpha beta t cell activation GO:0046631 91 0.012
regulation of hydrolase activity GO:0051336 246 0.012
positive regulation of organelle organization GO:0010638 128 0.012
protein kinase b signaling GO:0043491 74 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.012
positive regulation of cell cycle GO:0045787 92 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
regulation of protein localization GO:0032880 231 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
regulation of mapk cascade GO:0043408 248 0.012
lipid localization GO:0010876 126 0.012
regulation of ion homeostasis GO:2000021 64 0.012
positive regulation of nervous system development GO:0051962 221 0.012
lipid storage GO:0019915 36 0.012
retina development in camera type eye GO:0060041 119 0.012
signal transduction in absence of ligand GO:0038034 55 0.012
cellular chemical homeostasis GO:0055082 215 0.012
cellular response to peptide GO:1901653 92 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
regulation of cell migration GO:0030334 219 0.012
glial cell differentiation GO:0010001 131 0.012
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.012
tissue homeostasis GO:0001894 115 0.012
dna biosynthetic process GO:0071897 22 0.012
meiotic chromosome segregation GO:0045132 19 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
regulation of intracellular transport GO:0032386 159 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.011
protein catabolic process GO:0030163 221 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
atp metabolic process GO:0046034 75 0.011
blastocyst development GO:0001824 80 0.011
regulation of neuron death GO:1901214 134 0.011
rna processing GO:0006396 105 0.011
leukocyte apoptotic process GO:0071887 71 0.011
cell cycle switching GO:0060184 1 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
wnt signaling pathway GO:0016055 188 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
positive regulation of cell activation GO:0050867 158 0.011
tissue remodeling GO:0048771 102 0.011
muscle cell differentiation GO:0042692 261 0.011
response to growth factor GO:0070848 198 0.011
regulation of nuclear division GO:0051783 56 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
spermatid differentiation GO:0048515 115 0.011
ear morphogenesis GO:0042471 118 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
labyrinthine layer development GO:0060711 49 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
action potential GO:0001508 78 0.011
regulation of binding GO:0051098 111 0.011
detection of abiotic stimulus GO:0009582 60 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
tube formation GO:0035148 140 0.011
female gonad development GO:0008585 71 0.011
epithelial cell proliferation GO:0050673 174 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
nuclear transport GO:0051169 139 0.010
kidney development GO:0001822 213 0.010
purine nucleoside metabolic process GO:0042278 241 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
detection of external stimulus GO:0009581 61 0.010
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.010
determination of left right symmetry GO:0007368 80 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
nucleoside metabolic process GO:0009116 246 0.010
positive regulation of leukocyte mediated immunity GO:0002705 70 0.010
renal system development GO:0072001 225 0.010
cell growth GO:0016049 130 0.010
neuron apoptotic process GO:0051402 142 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
establishment of meiotic spindle orientation GO:0051296 1 0.010
t cell differentiation GO:0030217 174 0.010
regulation of cell projection organization GO:0031344 206 0.010
regulation of reproductive process GO:2000241 66 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
urogenital system development GO:0001655 261 0.010
protein targeting GO:0006605 143 0.010
dna packaging GO:0006323 30 0.010

Xrcc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.039
disease of anatomical entity DOID:7 0 0.039
hematopoietic system disease DOID:74 0 0.038
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
retinal disease DOID:5679 0 0.018
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.018
nervous system disease DOID:863 0 0.018
eye disease DOID:5614 0 0.018
organ system cancer DOID:0050686 0 0.015
immune system cancer DOID:0060083 0 0.014
hematologic cancer DOID:2531 0 0.014
retinal degeneration DOID:8466 0 0.012
musculoskeletal system disease DOID:17 0 0.011