Mus musculus

69 known processes

Xrcc6

X-ray repair complementing defective repair in Chinese hamster cells 6

(Aliases: G22p1,70kDa,Ku70)

Xrcc6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.277
dna repair GO:0006281 107 0.177
meiosis i GO:0007127 60 0.143
double strand break repair GO:0006302 48 0.110
cellular amino acid metabolic process GO:0006520 103 0.110
regulation of cellular amino acid metabolic process GO:0006521 5 0.106
non recombinational repair GO:0000726 10 0.093
somatic cell dna recombination GO:0016444 51 0.091
regulation of cellular ketone metabolic process GO:0010565 66 0.089
organelle fission GO:0048285 170 0.080
synapsis GO:0007129 34 0.076
regulation of cellular amine metabolic process GO:0033238 20 0.076
cellular response to dna damage stimulus GO:0006974 207 0.073
immune effector process GO:0002252 321 0.072
dna recombination GO:0006310 92 0.071
cell fate commitment GO:0045165 210 0.069
peptidyl amino acid modification GO:0018193 336 0.067
amine metabolic process GO:0009308 45 0.066
cellular amine metabolic process GO:0044106 44 0.062
cellular ketone metabolic process GO:0042180 84 0.062
nuclear division GO:0000280 158 0.060
meiotic cell cycle process GO:1903046 77 0.060
positive regulation of cellular amine metabolic process GO:0033240 5 0.060
microtubule cytoskeleton organization GO:0000226 157 0.057
protein maturation GO:0051604 176 0.057
macromolecule catabolic process GO:0009057 281 0.054
leukocyte mediated immunity GO:0002443 174 0.053
lymphocyte differentiation GO:0030098 242 0.053
apoptotic signaling pathway GO:0097190 306 0.053
double strand break repair via nonhomologous end joining GO:0006303 10 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.051
negative regulation of immune system process GO:0002683 209 0.049
rna 3 end processing GO:0031123 20 0.049
negative regulation of cell cycle GO:0045786 123 0.047
telomere maintenance GO:0000723 19 0.047
Fly
aromatic compound catabolic process GO:0019439 286 0.046
organic cyclic compound catabolic process GO:1901361 295 0.044
t cell activation GO:0042110 289 0.044
homeostasis of number of cells GO:0048872 210 0.044
chromosome organization involved in meiosis GO:0070192 39 0.042
regulation of mitotic cell cycle GO:0007346 126 0.042
protein processing GO:0016485 163 0.042
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.041
organelle assembly GO:0070925 177 0.040
anatomical structure homeostasis GO:0060249 145 0.039
Fly
lateral inhibition GO:0046331 1 0.039
somatic diversification of immunoglobulins GO:0016445 43 0.038
cellular macromolecule catabolic process GO:0044265 206 0.037
somatic diversification of immune receptors GO:0002200 53 0.037
chemotaxis GO:0006935 247 0.037
meiotic nuclear division GO:0007126 115 0.037
regulation of organelle organization GO:0033043 289 0.037
cell type specific apoptotic process GO:0097285 268 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.035
neuron apoptotic process GO:0051402 142 0.034
covalent chromatin modification GO:0016569 163 0.034
epithelial tube morphogenesis GO:0060562 303 0.034
regulation of cell cycle process GO:0010564 160 0.034
positive regulation of protein modification process GO:0031401 299 0.034
negative regulation of mitotic cell cycle GO:0045930 58 0.033
microtubule based process GO:0007017 236 0.033
telomere capping GO:0016233 4 0.032
chromatin organization GO:0006325 206 0.031
response to organonitrogen compound GO:0010243 246 0.031
cell activation involved in immune response GO:0002263 126 0.031
leukocyte differentiation GO:0002521 342 0.030
immunoglobulin production GO:0002377 73 0.030
dna conformation change GO:0071103 37 0.030
positive regulation of nervous system development GO:0051962 221 0.030
regulation of cell cycle GO:0051726 281 0.029
cytokine production GO:0001816 319 0.029
intrinsic apoptotic signaling pathway GO:0097193 132 0.029
forebrain development GO:0030900 302 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
intra s dna damage checkpoint GO:0031573 4 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.028
leukocyte activation involved in immune response GO:0002366 126 0.028
meiotic cell cycle GO:0051321 122 0.028
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.027
lymphocyte activation involved in immune response GO:0002285 93 0.027
positive regulation of cell death GO:0010942 224 0.027
b cell activation GO:0042113 161 0.026
gland development GO:0048732 330 0.026
heterocycle catabolic process GO:0046700 280 0.026
regulation of cell cycle phase transition GO:1901987 77 0.026
negative regulation of cellular amine metabolic process GO:0033239 1 0.026
immunoglobulin mediated immune response GO:0016064 69 0.025
protein modification by small protein conjugation or removal GO:0070647 207 0.025
positive regulation of cell development GO:0010720 237 0.025
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.025
regulation of membrane potential GO:0042391 192 0.025
production of molecular mediator of immune response GO:0002440 103 0.025
urogenital system development GO:0001655 261 0.025
adaptive immune response GO:0002250 155 0.024
stem cell differentiation GO:0048863 268 0.023
skeletal system development GO:0001501 356 0.023
histone modification GO:0016570 159 0.023
digestive tract development GO:0048565 190 0.022
myeloid cell differentiation GO:0030099 233 0.022
chromatin modification GO:0016568 187 0.022
base excision repair GO:0006284 9 0.022
protein secretion GO:0009306 111 0.022
negative regulation of cell cycle phase transition GO:1901988 48 0.021
multicellular organismal homeostasis GO:0048871 164 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
heart morphogenesis GO:0003007 178 0.021
maintenance of location GO:0051235 89 0.021
intracellular protein transport GO:0006886 204 0.021
cell cycle checkpoint GO:0000075 47 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
nuclear transport GO:0051169 139 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
cation transport GO:0006812 399 0.021
regulation of cell activation GO:0050865 289 0.021
mitotic cell cycle process GO:1903047 159 0.021
translation GO:0006412 93 0.021
blastocyst development GO:0001824 80 0.021
t cell differentiation GO:0030217 174 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
regulation of protein transport GO:0051223 163 0.020
lymphocyte mediated immunity GO:0002449 139 0.020
muscle tissue development GO:0060537 308 0.020
regulation of chromosome organization GO:0033044 83 0.020
cytoplasmic transport GO:0016482 234 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
regulation of defense response GO:0031347 233 0.020
germ cell development GO:0007281 185 0.020
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.020
dna catabolic process endonucleolytic GO:0000737 15 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
regulation of cytokine production GO:0001817 266 0.020
digestive system development GO:0055123 200 0.019
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.019
action potential GO:0001508 78 0.019
response to radiation GO:0009314 165 0.019
trna metabolic process GO:0006399 11 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
mitotic recombination GO:0006312 3 0.019
cellular homeostasis GO:0019725 240 0.019
regulation of secretion by cell GO:1903530 249 0.019
rna processing GO:0006396 105 0.018
wound healing GO:0042060 157 0.018
respiratory system development GO:0060541 190 0.018
camera type eye development GO:0043010 266 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
protein acylation GO:0043543 64 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
regulation of proteolysis GO:0030162 164 0.018
dna dependent dna replication GO:0006261 24 0.018
locomotory behavior GO:0007626 195 0.018
mitochondrion organization GO:0007005 134 0.018
lung development GO:0030324 164 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
regulation of kinase activity GO:0043549 249 0.018
inflammatory response GO:0006954 244 0.018
mitotic cell cycle GO:0000278 195 0.018
peptidyl lysine modification GO:0018205 77 0.018
spermatogenesis GO:0007283 284 0.018
dna catabolic process GO:0006308 19 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
myeloid leukocyte differentiation GO:0002573 119 0.017
protein catabolic process GO:0030163 221 0.017
regulation of protein processing GO:0070613 96 0.017
divalent metal ion transport GO:0070838 172 0.017
negative regulation of protein modification process GO:0031400 163 0.017
negative regulation of dna replication GO:0008156 4 0.017
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.017
muscle cell differentiation GO:0042692 261 0.017
defense response to other organism GO:0098542 197 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
regulation of mitotic cell cycle phase transition GO:1901990 73 0.017
leukocyte homeostasis GO:0001776 79 0.017
sensory perception GO:0007600 245 0.017
sister chromatid cohesion GO:0007062 12 0.017
response to oxidative stress GO:0006979 123 0.017
multicellular organism growth GO:0035264 161 0.017
regulation of protein maturation GO:1903317 96 0.016
cellular lipid metabolic process GO:0044255 323 0.016
regulation of neuron differentiation GO:0045664 281 0.016
oxidation reduction process GO:0055114 342 0.016
regulation of cellular protein catabolic process GO:1903362 61 0.016
response to lipopolysaccharide GO:0032496 128 0.016
regulation of transferase activity GO:0051338 263 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
mrna metabolic process GO:0016071 84 0.016
negative regulation of protein processing GO:0010955 79 0.016
neuromuscular process GO:0050905 99 0.016
negative regulation of cell cycle process GO:0010948 69 0.016
neuron death GO:0070997 154 0.016
methylation GO:0032259 134 0.016
response to organic cyclic compound GO:0014070 198 0.016
reciprocal meiotic recombination GO:0007131 16 0.015
regulation of protein catabolic process GO:0042176 108 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
dendrite development GO:0016358 115 0.015
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
cell growth GO:0016049 130 0.015
mrna 3 end processing GO:0031124 16 0.015
regulation of t cell activation GO:0050863 170 0.015
divalent inorganic cation transport GO:0072511 178 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
ras protein signal transduction GO:0007265 77 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
epithelial cell proliferation GO:0050673 174 0.015
t cell differentiation in thymus GO:0033077 77 0.015
regionalization GO:0003002 337 0.015
leukocyte migration GO:0050900 124 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
nucleotide metabolic process GO:0009117 332 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
chromosome segregation GO:0007059 48 0.014
response to growth factor GO:0070848 198 0.014
reciprocal dna recombination GO:0035825 16 0.014
response to inorganic substance GO:0010035 96 0.014
glial cell differentiation GO:0010001 131 0.014
stem cell development GO:0048864 219 0.014
b cell mediated immunity GO:0019724 71 0.014
regulation of protein localization GO:0032880 231 0.014
regulation of inflammatory response GO:0050727 147 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
negative regulation of protein maturation GO:1903318 79 0.014
respiratory tube development GO:0030323 167 0.014
organelle localization GO:0051640 179 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
cellular response to oxidative stress GO:0034599 76 0.014
innate immune response GO:0045087 157 0.014
neuronal action potential GO:0019228 54 0.014
leukocyte proliferation GO:0070661 172 0.014
nitrogen compound transport GO:0071705 271 0.014
male meiosis GO:0007140 37 0.014
dna replication GO:0006260 52 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.013
somitogenesis GO:0001756 69 0.013
b cell activation involved in immune response GO:0002312 50 0.013
tissue homeostasis GO:0001894 115 0.013
dephosphorylation GO:0016311 129 0.013
striated muscle tissue development GO:0014706 293 0.013
rna catabolic process GO:0006401 29 0.013
negative regulation of proteolysis GO:0045861 74 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
regulation of secretion GO:0051046 274 0.013
internal protein amino acid acetylation GO:0006475 42 0.013
axonogenesis GO:0007409 274 0.013
skin development GO:0043588 220 0.013
mapk cascade GO:0000165 281 0.013
regulation of hormone levels GO:0010817 211 0.013
multicellular organismal signaling GO:0035637 91 0.013
lipid biosynthetic process GO:0008610 179 0.013
chiasma assembly GO:0051026 6 0.013
mrna processing GO:0006397 63 0.013
retina development in camera type eye GO:0060041 119 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
generation of precursor metabolites and energy GO:0006091 103 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
positive regulation of protein autophosphorylation GO:0031954 4 0.013
gonad development GO:0008406 141 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
wnt signaling pathway GO:0016055 188 0.012
skeletal system morphogenesis GO:0048705 203 0.012
regulation of neuron projection development GO:0010975 169 0.012
response to oxygen levels GO:0070482 62 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
renal system development GO:0072001 225 0.012
positive regulation of transferase activity GO:0051347 167 0.012
nucleoside metabolic process GO:0009116 246 0.012
ear development GO:0043583 200 0.012
cardiac muscle tissue development GO:0048738 130 0.012
carbohydrate metabolic process GO:0005975 230 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
positive regulation of immune effector process GO:0002699 107 0.012
epidermis development GO:0008544 187 0.012
neural tube formation GO:0001841 108 0.012
negative regulation of neuron death GO:1901215 98 0.012
positive regulation of cell activation GO:0050867 158 0.012
antimicrobial peptide production GO:0002775 2 0.012
transmission of nerve impulse GO:0019226 76 0.012
regulation of cell projection organization GO:0031344 206 0.012
protein ubiquitination GO:0016567 171 0.012
cell division GO:0051301 120 0.012
cellular response to lipid GO:0071396 145 0.012
adult behavior GO:0030534 135 0.012
cellular protein catabolic process GO:0044257 155 0.011
female gamete generation GO:0007292 74 0.011
protein autophosphorylation GO:0046777 61 0.011
response to peptide GO:1901652 136 0.011
purine containing compound metabolic process GO:0072521 311 0.011
isotype switching GO:0045190 36 0.011
endocytosis GO:0006897 168 0.011
small molecule biosynthetic process GO:0044283 132 0.011
telencephalon development GO:0021537 186 0.011
cellular protein complex assembly GO:0043623 116 0.011
gene silencing GO:0016458 38 0.011
adult locomotory behavior GO:0008344 91 0.011
metaphase plate congression GO:0051310 2 0.011
cellular chemical homeostasis GO:0055082 215 0.011
trna aminoacylation GO:0043039 1 0.011
histone acetylation GO:0016573 41 0.011
regulation of cell motility GO:2000145 236 0.011
regulation of organ morphogenesis GO:2000027 144 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
metal ion homeostasis GO:0055065 189 0.011
angiogenesis GO:0001525 201 0.011
antibacterial peptide production GO:0002778 2 0.011
negative regulation of molecular function GO:0044092 258 0.011
hindbrain development GO:0030902 128 0.011
mitotic nuclear division GO:0007067 48 0.011
regulation of ion transport GO:0043269 215 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.011
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.011
protein modification by small protein conjugation GO:0032446 187 0.010
rna dependent dna replication GO:0006278 3 0.010
negative regulation of growth GO:0045926 99 0.010
cellular ion homeostasis GO:0006873 165 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
cation homeostasis GO:0055080 212 0.010
b cell differentiation GO:0030183 78 0.010
regulation of myeloid cell differentiation GO:0045637 96 0.010
defense response to bacterium GO:0042742 119 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
cajal body organization GO:0030576 1 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
determination of left right symmetry GO:0007368 80 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
regulation of hydrolase activity GO:0051336 246 0.010
digestive tract morphogenesis GO:0048546 147 0.010
kidney development GO:0001822 213 0.010
mismatch repair GO:0006298 8 0.010
response to peptide hormone GO:0043434 127 0.010
regulation of protein secretion GO:0050708 82 0.010

Xrcc6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.015
disease of anatomical entity DOID:7 0 0.015
hematopoietic system disease DOID:74 0 0.015
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
cancer DOID:162 0 0.013
nervous system disease DOID:863 0 0.012
central nervous system disease DOID:331 0 0.011
neurodegenerative disease DOID:1289 0 0.011