Mus musculus

7 known processes

Actn3

actinin alpha 3

(Aliases: MGC132876)

Actn3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle contraction GO:0006936 101 0.713
muscle system process GO:0003012 141 0.660
transmembrane transport GO:0055085 412 0.643
ribonucleoside metabolic process GO:0009119 245 0.484
regulation of skeletal muscle adaptation GO:0014733 12 0.465
muscle fiber development GO:0048747 76 0.456
skeletal muscle fiber development GO:0048741 58 0.437
oxidation reduction process GO:0055114 342 0.434
cardiac muscle cell development GO:0055013 39 0.428
atp metabolic process GO:0046034 75 0.420
cation transport GO:0006812 399 0.415
skeletal muscle organ development GO:0060538 163 0.410
metal ion homeostasis GO:0055065 189 0.405
skeletal muscle adaptation GO:0043501 16 0.400
cation homeostasis GO:0055080 212 0.400
inorganic ion transmembrane transport GO:0098660 234 0.385
cellular ion homeostasis GO:0006873 165 0.362
regulation of system process GO:0044057 200 0.355
striated muscle myosin thick filament assembly GO:0071688 1 0.345
organelle assembly GO:0070925 177 0.336
Fly
ion transmembrane transport GO:0034220 361 0.330
transition between fast and slow fiber GO:0014883 9 0.304
striated muscle contraction GO:0006941 45 0.301
inorganic cation transmembrane transport GO:0098662 207 0.285
myotube cell development GO:0014904 60 0.285
striated muscle cell development GO:0055002 125 0.282
Fly
camera type eye development GO:0043010 266 0.280
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.270
purine nucleoside triphosphate metabolic process GO:0009144 226 0.269
cation transmembrane transport GO:0098655 266 0.269
muscle cell differentiation GO:0042692 261 0.268
Fly
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.244
ribonucleoside triphosphate metabolic process GO:0009199 220 0.238
ribose phosphate metabolic process GO:0019693 291 0.237
striated muscle adaptation GO:0014888 26 0.237
actomyosin structure organization GO:0031032 56 0.233
Fly
ribonucleoside catabolic process GO:0042454 206 0.226
protein oligomerization GO:0051259 67 0.217
calcium ion homeostasis GO:0055074 127 0.210
nucleoside triphosphate metabolic process GO:0009141 230 0.209
purine containing compound metabolic process GO:0072521 311 0.208
purine nucleoside metabolic process GO:0042278 241 0.205
t cell activation GO:0042110 289 0.202
glycosyl compound metabolic process GO:1901657 246 0.201
nucleoside metabolic process GO:0009116 246 0.199
purine nucleoside monophosphate metabolic process GO:0009126 81 0.199
nucleoside monophosphate metabolic process GO:0009123 85 0.185
muscle tissue development GO:0060537 308 0.185
circulatory system process GO:0003013 197 0.180
myotube differentiation GO:0014902 105 0.175
myofibril assembly GO:0030239 34 0.174
Fly
myosin filament organization GO:0031033 3 0.174
cardiac muscle cell differentiation GO:0055007 69 0.171
regulation of muscle adaptation GO:0043502 31 0.169
divalent inorganic cation transport GO:0072511 178 0.168
translation GO:0006412 93 0.162
skeletal myofibril assembly GO:0014866 4 0.160
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.158
cell maturation GO:0048469 127 0.154
ribonucleoside triphosphate catabolic process GO:0009203 199 0.151
heart morphogenesis GO:0003007 178 0.151
actin mediated cell contraction GO:0070252 15 0.147
heart contraction GO:0060047 93 0.146
calcium ion transmembrane transport GO:0070588 85 0.143
muscle filament sliding GO:0030049 1 0.141
muscle cell development GO:0055001 133 0.138
Fly
actin cytoskeleton organization GO:0030036 220 0.137
Mouse Fly
cellular metal ion homeostasis GO:0006875 151 0.137
response to extracellular stimulus GO:0009991 127 0.132
muscle adaptation GO:0043500 39 0.132
cellular divalent inorganic cation homeostasis GO:0072503 127 0.129
cellular calcium ion homeostasis GO:0006874 119 0.128
purine nucleotide metabolic process GO:0006163 302 0.125
purine ribonucleoside metabolic process GO:0046128 241 0.123
regulation of skeletal muscle contraction GO:0014819 3 0.119
atp catabolic process GO:0006200 55 0.115
striated muscle tissue development GO:0014706 293 0.115
protein maturation GO:0051604 176 0.114
calcium ion transport GO:0006816 159 0.114
apoptotic signaling pathway GO:0097190 306 0.114
protein processing GO:0016485 163 0.112
cell type specific apoptotic process GO:0097285 268 0.111
purine ribonucleotide metabolic process GO:0009150 290 0.109
cellular component assembly involved in morphogenesis GO:0010927 139 0.109
Fly
purine containing compound catabolic process GO:0072523 213 0.107
cellular amine metabolic process GO:0044106 44 0.100
nucleobase containing small molecule metabolic process GO:0055086 352 0.100
cellular amino acid metabolic process GO:0006520 103 0.100
gas homeostasis GO:0033483 3 0.099
spemann organizer formation GO:0060061 2 0.099
nucleoside phosphate catabolic process GO:1901292 222 0.098
cellular response to oxidative stress GO:0034599 76 0.097
ribonucleotide metabolic process GO:0009259 291 0.093
regulation of muscle system process GO:0090257 80 0.093
cellular response to inorganic substance GO:0071241 37 0.093
ribonucleoside monophosphate catabolic process GO:0009158 57 0.092
ribonucleotide catabolic process GO:0009261 208 0.092
regulation of atp metabolic process GO:1903578 17 0.092
purine nucleoside catabolic process GO:0006152 205 0.091
membrane organization GO:0061024 245 0.088
uterus morphogenesis GO:0061038 2 0.086
cellular homeostasis GO:0019725 240 0.086
glycosyl compound catabolic process GO:1901658 206 0.084
protein modification by small protein conjugation GO:0032446 187 0.084
male gamete generation GO:0048232 285 0.084
oxygen homeostasis GO:0032364 2 0.084
organic anion transport GO:0015711 137 0.082
actin filament based movement GO:0030048 23 0.082
regulation of transmembrane transport GO:0034762 128 0.080
positive regulation of mitochondrial calcium ion concentration GO:0051561 3 0.079
cellular chemical homeostasis GO:0055082 215 0.079
heart process GO:0003015 94 0.078
divalent inorganic cation homeostasis GO:0072507 138 0.077
cellular amino acid biosynthetic process GO:0008652 22 0.076
ribonucleoside monophosphate metabolic process GO:0009161 80 0.075
regulation of body fluid levels GO:0050878 162 0.075
actin myosin filament sliding GO:0033275 1 0.075
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.075
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.072
maintenance of location GO:0051235 89 0.072
nitrogen compound transport GO:0071705 271 0.072
male meiosis GO:0007140 37 0.071
skin development GO:0043588 220 0.069
skeletal muscle thin filament assembly GO:0030240 2 0.069
response to activity GO:0014823 13 0.069
reactive oxygen species metabolic process GO:0072593 84 0.069
nucleotide metabolic process GO:0009117 332 0.068
epithelial cell development GO:0002064 159 0.067
regulation of ion transmembrane transport GO:0034765 119 0.067
cardiocyte differentiation GO:0035051 87 0.067
sequestering of calcium ion GO:0051208 18 0.066
regionalization GO:0003002 337 0.065
response to inorganic substance GO:0010035 96 0.065
regulation of protein maturation GO:1903317 96 0.065
muscle cell cellular homeostasis GO:0046716 12 0.064
spermatogenesis GO:0007283 284 0.064
protein localization to organelle GO:0033365 185 0.064
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.064
axis elongation involved in somitogenesis GO:0090245 4 0.063
regulation of intracellular transport GO:0032386 159 0.063
cellular modified amino acid metabolic process GO:0006575 63 0.063
positive regulation of glial cell proliferation GO:0060252 4 0.061
sarcomere organization GO:0045214 24 0.061
Fly
organonitrogen compound catabolic process GO:1901565 264 0.061
nucleoside triphosphate catabolic process GO:0009143 205 0.060
blood circulation GO:0008015 195 0.059
heterocycle catabolic process GO:0046700 280 0.059
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.059
carboxylic acid biosynthetic process GO:0046394 86 0.057
posttranscriptional regulation of gene expression GO:0010608 155 0.057
neurotransmitter transport GO:0006836 76 0.057
fatty acid metabolic process GO:0006631 121 0.057
negative regulation of growth GO:0045926 99 0.057
regulation of ion transport GO:0043269 215 0.056
myosin filament assembly GO:0031034 2 0.056
regulation of feeding behavior GO:0060259 3 0.055
multi multicellular organism process GO:0044706 109 0.055
kidney rudiment formation GO:0072003 3 0.055
mitotic cell cycle GO:0000278 195 0.055
Worm
respiratory system development GO:0060541 190 0.054
regulation of atp catabolic process GO:1903289 9 0.054
regulation of neuron apoptotic process GO:0043523 122 0.054
sperm motility GO:0030317 47 0.054
regulation of skeletal muscle fiber development GO:0048742 36 0.053
mesonephric duct morphogenesis GO:0072180 4 0.053
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.053
organophosphate catabolic process GO:0046434 232 0.053
cellular lipid metabolic process GO:0044255 323 0.053
regulation of protein processing GO:0070613 96 0.053
negative regulation of neuron death GO:1901215 98 0.053
cellular response to dna damage stimulus GO:0006974 207 0.053
response to oxidative stress GO:0006979 123 0.052
regulation of endocytosis GO:0030100 69 0.052
Mouse
nucleoside catabolic process GO:0009164 206 0.052
response to metal ion GO:0010038 47 0.052
cytoplasmic transport GO:0016482 234 0.051
regulation of heart contraction GO:0008016 77 0.051
cardiac right atrium morphogenesis GO:0003213 3 0.051
male meiosis i GO:0007141 16 0.050
nucleoside phosphate metabolic process GO:0006753 338 0.050
regulation of multi organism process GO:0043900 111 0.050
regulation of heart rate GO:0002027 36 0.050
peripheral nervous system neuron axonogenesis GO:0048936 3 0.050
lymphocyte proliferation GO:0046651 164 0.049
cardiac muscle tissue development GO:0048738 130 0.049
microtubule based process GO:0007017 236 0.048
regulation of homeostatic process GO:0032844 182 0.048
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.048
regulation of cellular catabolic process GO:0031329 242 0.047
homeostasis of number of cells GO:0048872 210 0.047
protein localization to membrane GO:0072657 108 0.047
sensory perception GO:0007600 245 0.047
cellular response to extracellular stimulus GO:0031668 81 0.047
regulation of neurotransmitter levels GO:0001505 87 0.047
skeletal muscle myosin thick filament assembly GO:0030241 1 0.046
ear development GO:0043583 200 0.046
regulation of peptidase activity GO:0052547 96 0.045
cardiac muscle contraction GO:0060048 32 0.045
negative regulation of hormone metabolic process GO:0032351 4 0.045
protein ubiquitination GO:0016567 171 0.044
regulation of protein kinase activity GO:0045859 232 0.044
sodium ion transmembrane transport GO:0035725 49 0.044
wound healing GO:0042060 157 0.044
regulation of purine nucleotide metabolic process GO:1900542 169 0.044
regulation of protein localization GO:0032880 231 0.044
sensory organ morphogenesis GO:0090596 242 0.043
protein modification by small protein conjugation or removal GO:0070647 207 0.043
regulation of cellular amine metabolic process GO:0033238 20 0.043
myeloid cell differentiation GO:0030099 233 0.043
negative regulation of cellular protein metabolic process GO:0032269 247 0.043
lymphocyte differentiation GO:0030098 242 0.043
cellular protein complex assembly GO:0043623 116 0.043
positive regulation of protein modification process GO:0031401 299 0.043
negative regulation of molecular function GO:0044092 258 0.042
intracellular protein transport GO:0006886 204 0.042
embryonic organ morphogenesis GO:0048562 276 0.042
organelle fission GO:0048285 170 0.042
Worm
regulation of proteolysis GO:0030162 164 0.042
urogenital system development GO:0001655 261 0.042
negative regulation of proteolysis GO:0045861 74 0.041
negative regulation of prostatic bud formation GO:0060686 4 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.041
purine ribonucleoside catabolic process GO:0046130 205 0.041
myeloid cell homeostasis GO:0002262 114 0.040
response to heat GO:0009408 27 0.040
acetate ester transport GO:1901374 2 0.040
aromatic compound catabolic process GO:0019439 286 0.040
response to starvation GO:0042594 65 0.039
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.039
columnar cuboidal epithelial cell maturation GO:0002069 4 0.039
gland development GO:0048732 330 0.039
response to organic cyclic compound GO:0014070 198 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.038
hematopoietic progenitor cell differentiation GO:0002244 143 0.038
circadian sleep wake cycle rem sleep GO:0042747 1 0.038
reactive oxygen species biosynthetic process GO:1903409 8 0.037
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.037
cartilage development GO:0051216 140 0.037
peripheral nervous system axon regeneration GO:0014012 2 0.037
sensory perception of sound GO:0007605 97 0.037
myotube differentiation involved in skeletal muscle regeneration GO:0014908 2 0.037
positive regulation of protein kinase activity GO:0045860 144 0.037
trachea cartilage morphogenesis GO:0060535 4 0.037
regulation of neuron death GO:1901214 134 0.036
regulation of vesicle mediated transport GO:0060627 139 0.036
Mouse
negative regulation of protein processing GO:0010955 79 0.036
developmental maturation GO:0021700 193 0.036
body morphogenesis GO:0010171 45 0.036
carbohydrate derivative catabolic process GO:1901136 231 0.036
locomotory behavior GO:0007626 195 0.036
Fly
nucleocytoplasmic transport GO:0006913 139 0.036
skeletal system development GO:0001501 356 0.036
cardiac cell development GO:0055006 41 0.036
protein complex disassembly GO:0043241 40 0.035
meiotic cell cycle GO:0051321 122 0.035
regulation of nucleotide metabolic process GO:0006140 169 0.035
energy derivation by oxidation of organic compounds GO:0015980 77 0.035
reactive nitrogen species metabolic process GO:2001057 0 0.035
regulation of nucleoside metabolic process GO:0009118 130 0.035
protein homooligomerization GO:0051260 43 0.035
regulation of anagen GO:0051884 1 0.034
acetylcholine secretion neurotransmission GO:0014055 2 0.034
regulation of apoptotic signaling pathway GO:2001233 197 0.034
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.034
positive regulation of interleukin 8 secretion GO:2000484 1 0.034
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.034
cellular response to cytokine stimulus GO:0071345 189 0.033
adaptive immune response GO:0002250 155 0.033
muscle cell fate specification GO:0042694 1 0.033
cerebellum formation GO:0021588 1 0.033
sequestering of metal ion GO:0051238 19 0.033
regulation of protein stability GO:0031647 52 0.033
protein catabolic process GO:0030163 221 0.032
Worm
t cell apoptotic process GO:0070231 39 0.032
cellular response to nutrient levels GO:0031669 64 0.032
response to inactivity GO:0014854 4 0.032
connective tissue development GO:0061448 179 0.032
lipid localization GO:0010876 126 0.032
ventral spinal cord development GO:0021517 48 0.032
fertilization GO:0009566 127 0.032
nucleoside monophosphate catabolic process GO:0009125 59 0.032
regulation of hormone levels GO:0010817 211 0.032
negative regulation of hormone biosynthetic process GO:0032353 4 0.031
respiratory tube development GO:0030323 167 0.031
cellular response to biotic stimulus GO:0071216 92 0.031
regulation of cell activation GO:0050865 289 0.031
midbrain hindbrain boundary maturation GO:0021732 1 0.031
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation GO:0044343 1 0.031
embryonic appendage morphogenesis GO:0035113 126 0.031
regulation of schwann cell proliferation GO:0010624 2 0.031
regulation of testosterone biosynthetic process GO:2000224 2 0.031
meiotic nuclear division GO:0007126 115 0.031
lymphocyte mediated immunity GO:0002449 139 0.031
placenta development GO:0001890 140 0.031
establishment of anatomical structure orientation GO:0048560 1 0.031
androgen biosynthetic process GO:0006702 4 0.031
negative regulation of cell proliferation GO:0008285 296 0.030
purine ribonucleotide catabolic process GO:0009154 208 0.030
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.030
acetylcholine transport GO:0015870 2 0.030
t cell differentiation in thymus GO:0033077 77 0.030
positive regulation of cell death GO:0010942 224 0.030
regulation of hydrolase activity GO:0051336 246 0.030
response to lipopolysaccharide GO:0032496 128 0.030
b cell differentiation GO:0030183 78 0.029
nucleotide catabolic process GO:0009166 217 0.029
negative regulation of synapse assembly GO:0051964 3 0.029
glutathione metabolic process GO:0006749 16 0.029
somite specification GO:0001757 4 0.029
regulation of cysteine type endopeptidase activity GO:2000116 65 0.029
rna interference GO:0016246 2 0.029
intestinal epithelial cell maturation GO:0060574 2 0.029
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.029
neurotransmitter secretion GO:0007269 62 0.029
schwann cell proliferation GO:0014010 2 0.029
mesonephric epithelium development GO:0072163 94 0.029
regulation of cell cycle process GO:0010564 160 0.029
cervix development GO:0060067 2 0.029
response to nutrient levels GO:0031667 109 0.028
blood vessel morphogenesis GO:0048514 285 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
nuclear division GO:0000280 158 0.028
Worm
protein targeting GO:0006605 143 0.028
regulation of establishment of protein localization GO:0070201 181 0.028
retina development in camera type eye GO:0060041 119 0.028
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.028
cell fate commitment GO:0045165 210 0.028
neural precursor cell proliferation GO:0061351 121 0.028
central nervous system vasculogenesis GO:0022009 3 0.027
cilium morphogenesis GO:0060271 102 0.027
negative regulation of potassium ion transmembrane transporter activity GO:1901017 3 0.027
regulation of blood pressure GO:0008217 93 0.027
cellular macromolecule catabolic process GO:0044265 206 0.027
morphogenesis of an epithelial fold GO:0060571 28 0.027
regulation of cytoplasmic transport GO:1903649 112 0.027
dna metabolic process GO:0006259 303 0.027
regulation of cellular response to stress GO:0080135 159 0.027
ossification GO:0001503 216 0.027
microtubule based movement GO:0007018 84 0.027
negative regulation of hydrolase activity GO:0051346 71 0.027
establishment of endothelial blood brain barrier GO:0014045 3 0.027
kidney development GO:0001822 213 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
metanephric loop of henle development GO:0072236 4 0.027
purine nucleotide catabolic process GO:0006195 211 0.027
regulation of transporter activity GO:0032409 57 0.027
cellular response to growth factor stimulus GO:0071363 197 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.026
cell junction organization GO:0034330 77 0.026
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.026
transition metal ion homeostasis GO:0055076 54 0.026
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.026
anion transport GO:0006820 177 0.026
regulation of cell cycle GO:0051726 281 0.026
limb development GO:0060173 166 0.026
renal system development GO:0072001 225 0.026
cellular response to starvation GO:0009267 57 0.026
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.026
purine nucleoside monophosphate catabolic process GO:0009128 58 0.026
establishment of protein localization to membrane GO:0090150 54 0.026
regulation of cell cycle g2 m phase transition GO:1902749 10 0.026
regulation of lymphocyte activation GO:0051249 240 0.025
positive regulation of transferase activity GO:0051347 167 0.025
cellular response to lipid GO:0071396 145 0.025
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.025
regulation of the force of heart contraction GO:0002026 17 0.025
wnt signaling pathway GO:0016055 188 0.025
regulation of cellular amino acid metabolic process GO:0006521 5 0.025
response to muscle stretch GO:0035994 1 0.025
regulation of anatomical structure size GO:0090066 178 0.025
cell cell junction organization GO:0045216 72 0.025
Mouse
neuron death GO:0070997 154 0.025
regulation of cellular response to growth factor stimulus GO:0090287 82 0.025
regulation of translation GO:0006417 71 0.025
positive regulation of growth GO:0045927 104 0.025
inflammatory response GO:0006954 244 0.025
mesonephric tubule development GO:0072164 94 0.024
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.024
skeletal system morphogenesis GO:0048705 203 0.024
hindbrain morphogenesis GO:0021575 46 0.024
epithelial cell differentiation involved in mammary gland alveolus development GO:0061030 4 0.024
regulation of response to wounding GO:1903034 189 0.024
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.024
multicellular organism growth GO:0035264 161 0.024
cellular response to external stimulus GO:0071496 88 0.024
neuron apoptotic process GO:0051402 142 0.024
bone development GO:0060348 120 0.024
embryonic limb morphogenesis GO:0030326 126 0.023
carbohydrate metabolic process GO:0005975 230 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.023
paramesonephric duct development GO:0061205 3 0.023
positive regulation of schwann cell proliferation GO:0010625 1 0.023
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.023
response to calcium ion GO:0051592 20 0.023
macromolecule catabolic process GO:0009057 281 0.023
Worm
anatomical structure homeostasis GO:0060249 145 0.023
regulation of chondrocyte differentiation GO:0032330 33 0.023
intermediate filament bundle assembly GO:0045110 3 0.023
sensory perception of pain GO:0019233 47 0.023
negative regulation of neuron apoptotic process GO:0043524 92 0.023
positive regulation of cell cycle process GO:0090068 61 0.023
oviduct development GO:0060066 3 0.023
carboxylic acid transport GO:0046942 100 0.023
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
skeletal muscle cell differentiation GO:0035914 66 0.022
negative regulation of alcohol biosynthetic process GO:1902931 4 0.022
cellular response to calcium ion GO:0071277 14 0.022
organic acid biosynthetic process GO:0016053 86 0.022
inner ear morphogenesis GO:0042472 101 0.022
regulation of mitotic cell cycle phase transition GO:1901990 73 0.022
cytokinetic process GO:0032506 2 0.022
cellular protein catabolic process GO:0044257 155 0.022
microtubule cytoskeleton organization GO:0000226 157 0.022
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.022
negative regulation of posttranscriptional gene silencing GO:0060149 1 0.022
cellular ketone metabolic process GO:0042180 84 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
cytokine mediated signaling pathway GO:0019221 115 0.022
regulation of organelle organization GO:0033043 289 0.022
smooth muscle contraction GO:0006939 44 0.022
photoreceptor cell differentiation GO:0046530 52 0.022
cell substrate adhesion GO:0031589 130 0.022
syncytium formation GO:0006949 43 0.022
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.021
cardiac muscle fiber development GO:0048739 4 0.021
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.021
cardiac myofibril assembly GO:0055003 12 0.021
embryonic skeletal system morphogenesis GO:0048704 91 0.021
mitotic chromosome condensation GO:0007076 1 0.021
cellular response to metal ion GO:0071248 31 0.021
kidney epithelium development GO:0072073 121 0.021
cell adhesion GO:0007155 329 0.021
morphogenesis of a branching structure GO:0001763 203 0.021
regulation of mitotic cell cycle GO:0007346 126 0.021
learning GO:0007612 98 0.021
myoblast differentiation GO:0045445 52 0.021
norepinephrine transport GO:0015874 2 0.021
glial cell differentiation GO:0010001 131 0.021
morphogenesis of a branching epithelium GO:0061138 193 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
generation of precursor metabolites and energy GO:0006091 103 0.021
leukocyte proliferation GO:0070661 172 0.021
negative regulation of protein modification process GO:0031400 163 0.021
regulation of blood circulation GO:1903522 93 0.021
regulation of ketone biosynthetic process GO:0010566 2 0.021
single organism nuclear import GO:1902593 95 0.021
cell matrix adhesion GO:0007160 68 0.021
regulation of actin filament based process GO:0032970 99 0.021
cell cell signaling involved in lung development GO:0060495 1 0.020
renal outer medulla development GO:0072054 2 0.020
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.020
positive regulation of anagen GO:0051885 1 0.020
regulation of sarcomere organization GO:0060297 4 0.020
negative regulation of gastrulation GO:2000542 3 0.020
regulation of canonical wnt signaling pathway GO:0060828 82 0.020
regulation of membrane potential GO:0042391 192 0.020
axon cargo transport GO:0008088 33 0.020
establishment of planar polarity GO:0001736 28 0.020
regulation of synaptic plasticity GO:0048167 87 0.020
response to radiation GO:0009314 165 0.020
adult behavior GO:0030534 135 0.020
Fly
multi organism behavior GO:0051705 62 0.020
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 10 0.020
renal vesicle induction GO:0072034 3 0.020
germ cell development GO:0007281 185 0.020
regulation of cellular component size GO:0032535 121 0.020
coagulation GO:0050817 78 0.020
intermediate filament cytoskeleton organization GO:0045104 26 0.020
multicellular organismal homeostasis GO:0048871 164 0.020
negative regulation of endopeptidase activity GO:0010951 44 0.020
appendage development GO:0048736 166 0.020
visual behavior GO:0007632 45 0.020
methylation GO:0032259 134 0.020
monocarboxylic acid metabolic process GO:0032787 191 0.020
inner medullary collecting duct development GO:0072061 2 0.020
lateral inhibition GO:0046331 1 0.019
cardiac septum development GO:0003279 59 0.019
spermatid differentiation GO:0048515 115 0.019
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.019
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.019
telencephalon development GO:0021537 186 0.019
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.019
regulation of leukocyte differentiation GO:1902105 159 0.019
developmental growth involved in morphogenesis GO:0060560 138 0.019
response to steroid hormone GO:0048545 56 0.019
regulation of defense response GO:0031347 233 0.019

Actn3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.550
disease of anatomical entity DOID:7 0 0.550
musculoskeletal system disease DOID:17 0 0.550
muscle tissue disease DOID:66 0 0.550
myopathy DOID:423 0 0.056
neuromuscular disease DOID:440 0 0.036
nervous system disease DOID:863 0 0.036
neuropathy DOID:870 0 0.036
connective tissue disease DOID:65 0 0.021