Mus musculus

43 known processes

Msh3

mutS homolog 3 (E. coli)

(Aliases: Rep3,Rep-3,D13Em1)

Msh3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.078
dna repair GO:0006281 107 0.050
cellular amino acid metabolic process GO:0006520 103 0.049
transmembrane transport GO:0055085 412 0.047
male gamete generation GO:0048232 285 0.046
cellular nitrogen compound catabolic process GO:0044270 280 0.044
Yeast
nucleoside phosphate metabolic process GO:0006753 338 0.043
Yeast
spermatogenesis GO:0007283 284 0.043
nucleotide metabolic process GO:0009117 332 0.042
Yeast
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.041
cellular ketone metabolic process GO:0042180 84 0.040
amine metabolic process GO:0009308 45 0.039
regulation of organelle organization GO:0033043 289 0.039
cellular response to dna damage stimulus GO:0006974 207 0.038
cellular amine metabolic process GO:0044106 44 0.037
organic cyclic compound catabolic process GO:1901361 295 0.037
Yeast
lymphocyte differentiation GO:0030098 242 0.036
nucleoside triphosphate catabolic process GO:0009143 205 0.036
Yeast
nucleoside phosphate catabolic process GO:1901292 222 0.035
Yeast
regulation of cell cycle GO:0051726 281 0.035
organonitrogen compound catabolic process GO:1901565 264 0.035
Yeast
nucleoside triphosphate metabolic process GO:0009141 230 0.034
Yeast
ribose phosphate metabolic process GO:0019693 291 0.034
Yeast
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
Yeast
heterocycle catabolic process GO:0046700 280 0.033
Yeast
apoptotic signaling pathway GO:0097190 306 0.033
chromatin organization GO:0006325 206 0.032
ion transmembrane transport GO:0034220 361 0.032
purine containing compound metabolic process GO:0072521 311 0.032
Yeast
ribonucleotide metabolic process GO:0009259 291 0.032
Yeast
organophosphate catabolic process GO:0046434 232 0.032
Yeast
carbohydrate derivative catabolic process GO:1901136 231 0.032
Yeast
small gtpase mediated signal transduction GO:0007264 97 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
Yeast
dna recombination GO:0006310 92 0.030
meiotic nuclear division GO:0007126 115 0.030
t cell activation GO:0042110 289 0.030
peptidyl amino acid modification GO:0018193 336 0.029
nucleotide catabolic process GO:0009166 217 0.029
Yeast
regulation of cellular amine metabolic process GO:0033238 20 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
organelle fission GO:0048285 170 0.029
nucleoside metabolic process GO:0009116 246 0.029
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
Yeast
germ cell development GO:0007281 185 0.029
aromatic compound catabolic process GO:0019439 286 0.028
Yeast
glycosyl compound metabolic process GO:1901657 246 0.028
Yeast
purine nucleotide catabolic process GO:0006195 211 0.028
Yeast
purine nucleoside catabolic process GO:0006152 205 0.028
Yeast
purine nucleotide metabolic process GO:0006163 302 0.028
Yeast
purine containing compound catabolic process GO:0072523 213 0.027
Yeast
meiotic cell cycle GO:0051321 122 0.027
leukocyte differentiation GO:0002521 342 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.027
Yeast
regulation of mapk cascade GO:0043408 248 0.027
ribonucleoside catabolic process GO:0042454 206 0.027
Yeast
inorganic ion transmembrane transport GO:0098660 234 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.026
Yeast
purine nucleoside metabolic process GO:0042278 241 0.026
Yeast
regulation of protein kinase activity GO:0045859 232 0.026
glycosyl compound catabolic process GO:1901658 206 0.025
Yeast
nucleoside catabolic process GO:0009164 206 0.025
Yeast
mitotic cell cycle GO:0000278 195 0.025
ras protein signal transduction GO:0007265 77 0.025
regulation of t cell activation GO:0050863 170 0.025
meiotic cell cycle process GO:1903046 77 0.025
nuclear division GO:0000280 158 0.025
microtubule based process GO:0007017 236 0.025
ribonucleotide catabolic process GO:0009261 208 0.024
Yeast
chromatin modification GO:0016568 187 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
Yeast
regulation of lymphocyte activation GO:0051249 240 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 199 0.024
Yeast
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
Yeast
microtubule cytoskeleton organization GO:0000226 157 0.024
carbohydrate metabolic process GO:0005975 230 0.024
mapk cascade GO:0000165 281 0.023
covalent chromatin modification GO:0016569 163 0.023
endomembrane system organization GO:0010256 147 0.023
cation transmembrane transport GO:0098655 266 0.023
regulation of apoptotic signaling pathway GO:2001233 197 0.023
regulation of membrane potential GO:0042391 192 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
Yeast
positive regulation of organelle organization GO:0010638 128 0.022
cell adhesion GO:0007155 329 0.022
immune effector process GO:0002252 321 0.022
positive regulation of protein modification process GO:0031401 299 0.021
cellular homeostasis GO:0019725 240 0.021
mitotic cell cycle process GO:1903047 159 0.021
cation transport GO:0006812 399 0.021
negative regulation of molecular function GO:0044092 258 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
synaptic transmission GO:0007268 329 0.021
fertilization GO:0009566 127 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
regulation of cell activation GO:0050865 289 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
Yeast
cellular response to organonitrogen compound GO:0071417 145 0.020
cytoplasmic transport GO:0016482 234 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
Yeast
membrane organization GO:0061024 245 0.019
regionalization GO:0003002 337 0.019
cytokine production GO:0001816 319 0.019
b cell activation GO:0042113 161 0.019
macromolecule methylation GO:0043414 120 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
intracellular protein transport GO:0006886 204 0.019
protein processing GO:0016485 163 0.019
transmission of nerve impulse GO:0019226 76 0.019
negative regulation of synapse assembly GO:0051964 3 0.019
protein maturation GO:0051604 176 0.019
response to organonitrogen compound GO:0010243 246 0.019
regulation of secretion GO:0051046 274 0.019
regulation of hydrolase activity GO:0051336 246 0.019
Human
methylation GO:0032259 134 0.019
histone modification GO:0016570 159 0.019
regulation of protein localization GO:0032880 231 0.019
multicellular organism growth GO:0035264 161 0.019
lymphocyte mediated immunity GO:0002449 139 0.018
cilium assembly GO:0042384 81 0.018
nitrogen compound transport GO:0071705 271 0.018
t cell differentiation GO:0030217 174 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
organelle localization GO:0051640 179 0.018
positive regulation of cell cycle GO:0045787 92 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.017
regulation of cell projection organization GO:0031344 206 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
anatomical structure homeostasis GO:0060249 145 0.017
response to acid chemical GO:0001101 111 0.017
cellular protein complex assembly GO:0043623 116 0.017
maintenance of location GO:0051235 89 0.017
spermatid differentiation GO:0048515 115 0.017
digestive tract development GO:0048565 190 0.017
striated muscle tissue development GO:0014706 293 0.017
protein localization to organelle GO:0033365 185 0.017
regulation of transferase activity GO:0051338 263 0.017
regulation of kinase activity GO:0043549 249 0.017
regulation of cell cycle process GO:0010564 160 0.016
negative regulation of immune system process GO:0002683 209 0.016
divalent inorganic cation transport GO:0072511 178 0.016
spermatid development GO:0007286 108 0.016
rna processing GO:0006396 105 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
gland development GO:0048732 330 0.016
negative regulation of cell cycle GO:0045786 123 0.016
protein ubiquitination GO:0016567 171 0.016
cell activation involved in immune response GO:0002263 126 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
cilium morphogenesis GO:0060271 102 0.016
glycoprotein metabolic process GO:0009100 116 0.016
gtp metabolic process GO:0046039 144 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
regulation of intracellular transport GO:0032386 159 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
muscle tissue development GO:0060537 308 0.016
organelle assembly GO:0070925 177 0.015
cell type specific apoptotic process GO:0097285 268 0.015
activation of immune response GO:0002253 138 0.015
forebrain development GO:0030900 302 0.015
endocytosis GO:0006897 168 0.015
positive regulation of cell activation GO:0050867 158 0.015
leukocyte proliferation GO:0070661 172 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
macromolecule catabolic process GO:0009057 281 0.015
rho protein signal transduction GO:0007266 32 0.015
regulation of cytokine production GO:0001817 266 0.015
regulation of translation GO:0006417 71 0.015
regulation of lymphocyte differentiation GO:0045619 107 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
protein localization to nucleus GO:0034504 121 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
synapse organization GO:0050808 125 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
leukocyte mediated immunity GO:0002443 174 0.014
cellular lipid metabolic process GO:0044255 323 0.014
divalent metal ion transport GO:0070838 172 0.014
regulation of cellular component size GO:0032535 121 0.014
protein polymerization GO:0051258 57 0.013
stem cell differentiation GO:0048863 268 0.013
regulation of cell division GO:0051302 76 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
innate immune response GO:0045087 157 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
cell fate commitment GO:0045165 210 0.013
regulation of secretion by cell GO:1903530 249 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
sequestering of metal ion GO:0051238 19 0.013
homeostasis of number of cells GO:0048872 210 0.013
cation homeostasis GO:0055080 212 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
protein catabolic process GO:0030163 221 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
immune response regulating signaling pathway GO:0002764 125 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
nuclear transport GO:0051169 139 0.013
cellular macromolecule catabolic process GO:0044265 206 0.012
regulation of proteolysis GO:0030162 164 0.012
anion transport GO:0006820 177 0.012
cell growth GO:0016049 130 0.012
tissue homeostasis GO:0001894 115 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
cellular chemical homeostasis GO:0055082 215 0.012
neuronal action potential GO:0019228 54 0.012
neural tube development GO:0021915 160 0.012
regulation of binding GO:0051098 111 0.012
skeletal system morphogenesis GO:0048705 203 0.012
regulation of cellular response to stress GO:0080135 159 0.012
translation GO:0006412 93 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
positive regulation of cell development GO:0010720 237 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
response to amino acid GO:0043200 37 0.012
calcium ion homeostasis GO:0055074 127 0.012
cell division GO:0051301 120 0.012
peptidyl serine modification GO:0018209 83 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
Yeast
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
Yeast
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
Yeast
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
calcium ion transport GO:0006816 159 0.012
regulation of anatomical structure size GO:0090066 178 0.012
lymphocyte proliferation GO:0046651 164 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
action potential GO:0001508 78 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
chemotaxis GO:0006935 247 0.011
establishment or maintenance of cell polarity GO:0007163 86 0.011
cellular ion homeostasis GO:0006873 165 0.011
glycosylation GO:0070085 62 0.011
skeletal muscle organ development GO:0060538 163 0.011
respiratory system development GO:0060541 190 0.011
amide transport GO:0042886 138 0.011
cellular protein catabolic process GO:0044257 155 0.011
regulation of ion transport GO:0043269 215 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
histone methylation GO:0016571 71 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
Yeast
cellular response to hormone stimulus GO:0032870 150 0.011
protein targeting GO:0006605 143 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
adaptive immune response GO:0002250 155 0.011
metal ion homeostasis GO:0055065 189 0.011
response to lipopolysaccharide GO:0032496 128 0.011
regulation of hormone levels GO:0010817 211 0.011
telencephalon development GO:0021537 186 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
protein localization to membrane GO:0072657 108 0.011
regulation of leukocyte mediated immunity GO:0002703 104 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
regulation of defense response GO:0031347 233 0.011
regulation of protein maturation GO:1903317 96 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
Yeast
alpha beta t cell activation GO:0046631 91 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
wnt signaling pathway GO:0016055 188 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
male meiosis GO:0007140 37 0.011
cellular response to acid chemical GO:0071229 68 0.011
cell substrate adhesion GO:0031589 130 0.011
stem cell maintenance GO:0019827 130 0.011
t cell proliferation GO:0042098 120 0.011
positive regulation of nervous system development GO:0051962 221 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
urogenital system development GO:0001655 261 0.011
response to growth factor GO:0070848 198 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
developmental maturation GO:0021700 193 0.011
sequestering of calcium ion GO:0051208 18 0.011
neural tube formation GO:0001841 108 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
positive regulation of t cell activation GO:0050870 101 0.011
blastocyst development GO:0001824 80 0.011
response to radiation GO:0009314 165 0.011
exocytosis GO:0006887 121 0.011
sensory perception GO:0007600 245 0.011
regulation of b cell activation GO:0050864 81 0.011
regulation of multi organism process GO:0043900 111 0.011
lateral inhibition GO:0046331 1 0.011
mrna metabolic process GO:0016071 84 0.011
negative regulation of protein modification process GO:0031400 163 0.011
muscle cell differentiation GO:0042692 261 0.011
positive regulation of apoptotic process GO:0043065 217 0.010
regulation of lymphocyte mediated immunity GO:0002706 84 0.010
cognition GO:0050890 149 0.010
meiosis i GO:0007127 60 0.010
digestive system development GO:0055123 200 0.010
single fertilization GO:0007338 82 0.010
regulation of homeostatic process GO:0032844 182 0.010
establishment of protein localization to organelle GO:0072594 118 0.010
peptidyl tyrosine phosphorylation GO:0018108 143 0.010
epithelial tube formation GO:0072175 130 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
mitotic cytokinesis GO:0000281 4 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
double strand break repair GO:0006302 48 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.010
mitochondrion organization GO:0007005 134 0.010
Yeast
neuron death GO:0070997 154 0.010
adult behavior GO:0030534 135 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
regulation of purine nucleotide catabolic process GO:0033121 122 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
guanosine containing compound catabolic process GO:1901069 144 0.010
humoral immune response GO:0006959 57 0.010
tube formation GO:0035148 140 0.010

Msh3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
immune system disease DOID:2914 0 0.020
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
sensory system disease DOID:0050155 0 0.017
central nervous system disease DOID:331 0 0.014
musculoskeletal system disease DOID:17 0 0.013
hematopoietic system disease DOID:74 0 0.012