Mus musculus

52 known processes

Msh4

mutS homolog 4 (E. coli)

(Aliases: mMsh4,4930485C04Rik,AV144863)

Msh4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pirna metabolic process GO:0034587 12 0.361
spermatogenesis GO:0007283 284 0.263
male gamete generation GO:0048232 285 0.224
germ cell development GO:0007281 185 0.199
dna methylation involved in gamete generation GO:0043046 15 0.190
spermatid differentiation GO:0048515 115 0.108
cellular amino acid metabolic process GO:0006520 103 0.086
male meiosis GO:0007140 37 0.076
oxidation reduction process GO:0055114 342 0.067
ion transmembrane transport GO:0034220 361 0.066
epidermis development GO:0008544 187 0.062
amine metabolic process GO:0009308 45 0.062
positive regulation of cellular amine metabolic process GO:0033240 5 0.061
nucleoside phosphate metabolic process GO:0006753 338 0.057
meiotic cell cycle GO:0051321 122 0.055
meiotic nuclear division GO:0007126 115 0.054
developmental maturation GO:0021700 193 0.054
positive regulation of protein modification process GO:0031401 299 0.052
posttranscriptional regulation of gene expression GO:0010608 155 0.051
microtubule cytoskeleton organization GO:0000226 157 0.051
spermatid development GO:0007286 108 0.051
negative regulation of protein metabolic process GO:0051248 282 0.049
peptidyl amino acid modification GO:0018193 336 0.048
macromolecule methylation GO:0043414 120 0.047
dna metabolic process GO:0006259 303 0.046
Yeast
negative regulation of molecular function GO:0044092 258 0.045
methylation GO:0032259 134 0.041
negative regulation of cellular protein metabolic process GO:0032269 247 0.041
proteoglycan metabolic process GO:0006029 38 0.041
gene silencing by rna GO:0031047 19 0.039
organelle fission GO:0048285 170 0.039
response to organonitrogen compound GO:0010243 246 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.036
cellular nitrogen compound catabolic process GO:0044270 280 0.036
purine ribonucleotide metabolic process GO:0009150 290 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.035
regulation of cellular catabolic process GO:0031329 242 0.035
multicellular organism growth GO:0035264 161 0.035
actin cytoskeleton organization GO:0030036 220 0.034
kidney development GO:0001822 213 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.033
regulation of cellular component biogenesis GO:0044087 181 0.033
cation transmembrane transport GO:0098655 266 0.032
protein modification by small protein conjugation GO:0032446 187 0.032
anion transport GO:0006820 177 0.032
nuclear division GO:0000280 158 0.032
heterocycle catabolic process GO:0046700 280 0.032
nucleotide metabolic process GO:0009117 332 0.031
striated muscle tissue development GO:0014706 293 0.031
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.031
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
macromolecule catabolic process GO:0009057 281 0.031
cellular amine metabolic process GO:0044106 44 0.030
cellular macromolecule catabolic process GO:0044265 206 0.030
gland development GO:0048732 330 0.030
dna modification GO:0006304 50 0.029
ribonucleotide catabolic process GO:0009261 208 0.029
regionalization GO:0003002 337 0.028
purine containing compound catabolic process GO:0072523 213 0.028
regulation of transferase activity GO:0051338 263 0.027
positive regulation of protein phosphorylation GO:0001934 242 0.027
organonitrogen compound catabolic process GO:1901565 264 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
protein catabolic process GO:0030163 221 0.026
sulfur compound metabolic process GO:0006790 100 0.026
oocyte axis specification GO:0007309 2 0.026
dna methylation GO:0006306 43 0.026
positive regulation of programmed cell death GO:0043068 218 0.026
urogenital system development GO:0001655 261 0.025
purine ribonucleoside catabolic process GO:0046130 205 0.025
stem cell development GO:0048864 219 0.025
skin development GO:0043588 220 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
sensory perception GO:0007600 245 0.025
regulation of proteolysis GO:0030162 164 0.025
fertilization GO:0009566 127 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
neuronal action potential GO:0019228 54 0.024
inorganic ion transmembrane transport GO:0098660 234 0.024
regulation of microvillus organization GO:0032530 3 0.024
multi multicellular organism process GO:0044706 109 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
protein ubiquitination GO:0016567 171 0.024
sodium ion transport GO:0006814 73 0.024
regulation of organelle organization GO:0033043 289 0.023
positive regulation of cell death GO:0010942 224 0.023
regulation of actin filament based process GO:0032970 99 0.023
oocyte construction GO:0007308 2 0.023
aromatic compound catabolic process GO:0019439 286 0.023
oocyte differentiation GO:0009994 35 0.023
dna alkylation GO:0006305 43 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
negative regulation of nik nf kappab signaling GO:1901223 2 0.023
stem cell differentiation GO:0048863 268 0.023
rna interference GO:0016246 2 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
cation transport GO:0006812 399 0.022
regulation of kinase activity GO:0043549 249 0.022
nucleocytoplasmic transport GO:0006913 139 0.022
extracellular structure organization GO:0043062 148 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
meiotic cell cycle process GO:1903046 77 0.021
muscle cell differentiation GO:0042692 261 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
cellular ketone metabolic process GO:0042180 84 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
transmembrane transport GO:0055085 412 0.021
blood vessel morphogenesis GO:0048514 285 0.020
regulation of cell motility GO:2000145 236 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
female sex differentiation GO:0046660 84 0.020
gene silencing GO:0016458 38 0.020
regulation of peptidase activity GO:0052547 96 0.020
cell maturation GO:0048469 127 0.020
renal system development GO:0072001 225 0.020
organophosphate catabolic process GO:0046434 232 0.020
meiosis i GO:0007127 60 0.020
positive regulation of cell migration GO:0030335 109 0.020
muscle tissue development GO:0060537 308 0.020
skeletal muscle organ development GO:0060538 163 0.020
protein processing GO:0016485 163 0.019
negative regulation of protein processing GO:0010955 79 0.019
skeletal system morphogenesis GO:0048705 203 0.019
peptidyl serine modification GO:0018209 83 0.019
muscle cell development GO:0055001 133 0.019
response to organic cyclic compound GO:0014070 198 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
development of primary female sexual characteristics GO:0046545 73 0.019
regulation of binding GO:0051098 111 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
intracellular mrna localization GO:0008298 4 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
purine nucleotide catabolic process GO:0006195 211 0.018
microtubule based process GO:0007017 236 0.018
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.018
regulation of cell cycle GO:0051726 281 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.018
glycoprotein metabolic process GO:0009100 116 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
regulation of striated muscle cell differentiation GO:0051153 81 0.018
organic acid transport GO:0015849 101 0.018
nucleoside metabolic process GO:0009116 246 0.018
ossification GO:0001503 216 0.018
cellular component assembly involved in morphogenesis GO:0010927 139 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
translation GO:0006412 93 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
blood circulation GO:0008015 195 0.017
negative regulation of proteolysis GO:0045861 74 0.017
intracellular protein transport GO:0006886 204 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
regulation of reproductive process GO:2000241 66 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
regulation of translation GO:0006417 71 0.017
posttranscriptional gene silencing by rna GO:0035194 10 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
pole plasm assembly GO:0007315 2 0.017
response to acid chemical GO:0001101 111 0.017
stem cell maintenance GO:0019827 130 0.017
cellular protein catabolic process GO:0044257 155 0.017
multicellular organismal signaling GO:0035637 91 0.017
purine containing compound metabolic process GO:0072521 311 0.016
nucleotide catabolic process GO:0009166 217 0.016
regulation of mapk cascade GO:0043408 248 0.016
regulation of intracellular transport GO:0032386 159 0.016
single fertilization GO:0007338 82 0.016
chondroitin sulfate proteoglycan metabolic process GO:0050654 20 0.016
t cell activation GO:0042110 289 0.016
regulation of cell migration GO:0030334 219 0.016
regulation of protein maturation GO:1903317 96 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
homeostasis of number of cells GO:0048872 210 0.016
striated muscle cell development GO:0055002 125 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
potassium ion homeostasis GO:0055075 4 0.015
negative regulation of protein maturation GO:1903318 79 0.015
female gamete generation GO:0007292 74 0.015
organ growth GO:0035265 117 0.015
telencephalon development GO:0021537 186 0.015
germ line stem cell division GO:0042078 2 0.015
negative regulation of protein modification process GO:0031400 163 0.015
negative regulation of cell migration GO:0030336 59 0.015
cation homeostasis GO:0055080 212 0.015
maternal determination of anterior posterior axis embryo GO:0008358 2 0.015
apoptotic signaling pathway GO:0097190 306 0.015
ribonucleoside catabolic process GO:0042454 206 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
gonad development GO:0008406 141 0.014
myotube differentiation GO:0014902 105 0.014
rhythmic process GO:0048511 174 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
regulation of microvillus assembly GO:0032534 3 0.014
heart contraction GO:0060047 93 0.014
regulation of hydrolase activity GO:0051336 246 0.014
regulation of protein processing GO:0070613 96 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
epithelial cell development GO:0002064 159 0.014
negative regulation of endopeptidase activity GO:0010951 44 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
regulation of anatomical structure size GO:0090066 178 0.014
synapse organization GO:0050808 125 0.014
posttranscriptional gene silencing GO:0016441 10 0.014
carbohydrate metabolic process GO:0005975 230 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
lateral inhibition GO:0046331 1 0.014
development of primary sexual characteristics GO:0045137 143 0.014
regulation of cell cycle process GO:0010564 160 0.014
molting cycle GO:0042303 90 0.014
positive regulation of growth GO:0045927 104 0.013
regulation of cell activation GO:0050865 289 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
regulation of membrane potential GO:0042391 192 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
nuclear transport GO:0051169 139 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
nitrogen compound transport GO:0071705 271 0.013
protein maturation GO:0051604 176 0.013
organic anion transport GO:0015711 137 0.013
muscle contraction GO:0006936 101 0.013
dephosphorylation GO:0016311 129 0.013
nucleoside catabolic process GO:0009164 206 0.013
protein targeting GO:0006605 143 0.013
myotube cell development GO:0014904 60 0.013
sensory perception of sound GO:0007605 97 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
negative regulation of cell development GO:0010721 169 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
male gonad development GO:0008584 88 0.013
oocyte development GO:0048599 33 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
negative regulation of endothelial cell migration GO:0010596 4 0.013
cellularization GO:0007349 1 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
bone development GO:0060348 120 0.013
atp metabolic process GO:0046034 75 0.013
mapk cascade GO:0000165 281 0.013
myeloid cell differentiation GO:0030099 233 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.012
positive regulation of cell development GO:0010720 237 0.012
regulation of protein catabolic process GO:0042176 108 0.012
female gonad development GO:0008585 71 0.012
oogenesis GO:0048477 56 0.012
negative regulation of kinase activity GO:0033673 81 0.012
cell type specific apoptotic process GO:0097285 268 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
regulation of neural precursor cell proliferation GO:2000177 70 0.012
heterochromatin organization GO:0070828 4 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
regulation of protein kinase activity GO:0045859 232 0.012
tube formation GO:0035148 140 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
hair cycle GO:0042633 90 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
positive regulation of transferase activity GO:0051347 167 0.012
action potential GO:0001508 78 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
aminoglycan metabolic process GO:0006022 34 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
mrna metabolic process GO:0016071 84 0.012
circulatory system process GO:0003013 197 0.012
oocyte anterior posterior axis specification GO:0007314 2 0.011
leukocyte migration GO:0050900 124 0.011
cell growth GO:0016049 130 0.011
cellular protein complex assembly GO:0043623 116 0.011
neural tube development GO:0021915 160 0.011
cofactor metabolic process GO:0051186 80 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
ensheathment of neurons GO:0007272 76 0.011
rna processing GO:0006396 105 0.011
regulation of cell growth GO:0001558 91 0.011
regulation of secretion GO:0051046 274 0.011
regulation of transposition GO:0010528 2 0.011
protein localization to organelle GO:0033365 185 0.011
fat cell differentiation GO:0045444 160 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of cell adhesion GO:0030155 154 0.011
muscle system process GO:0003012 141 0.011
nuclear import GO:0051170 95 0.011
glucose metabolic process GO:0006006 92 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
segmentation GO:0035282 93 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
anion transmembrane transport GO:0098656 71 0.011
cytoplasmic transport GO:0016482 234 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.011
mitotic cytokinesis GO:0000281 4 0.011
organelle assembly GO:0070925 177 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
stem cell proliferation GO:0072089 117 0.011
hexose metabolic process GO:0019318 98 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
sensory perception of chemical stimulus GO:0007606 51 0.010
epithelial tube formation GO:0072175 130 0.010
protein localization to membrane GO:0072657 108 0.010
positive regulation of cell adhesion GO:0045785 80 0.010
cellular lipid metabolic process GO:0044255 323 0.010
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.010
connective tissue development GO:0061448 179 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
camera type eye development GO:0043010 266 0.010
regulation of endopeptidase activity GO:0052548 89 0.010
heart process GO:0003015 94 0.010
negative regulation of transferase activity GO:0051348 85 0.010
cilium morphogenesis GO:0060271 102 0.010
rho protein signal transduction GO:0007266 32 0.010
negative regulation of cell motility GO:2000146 61 0.010
regulation of cellular protein catabolic process GO:1903362 61 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010

Msh4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010