Mus musculus

148 known processes

Atm

ataxia telangiectasia mutated homolog (human)

(Aliases: AI256621,C030026E19Rik)

Atm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 207 0.999
dna repair GO:0006281 107 0.999
dna metabolic process GO:0006259 303 0.998
telomere maintenance GO:0000723 19 0.998
Fly
dna recombination GO:0006310 92 0.997
somatic diversification of immune receptors GO:0002200 53 0.996
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.994
response to x ray GO:0010165 11 0.988
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.986
response to ionizing radiation GO:0010212 42 0.985
meiotic cell cycle GO:0051321 122 0.962
Worm Fly
intrinsic apoptotic signaling pathway GO:0097193 132 0.958
response to radiation GO:0009314 165 0.947
negative regulation of dna replication GO:0008156 4 0.941
non recombinational repair GO:0000726 10 0.940
double strand break repair GO:0006302 48 0.939
Fly
immunoglobulin production GO:0002377 73 0.937
production of molecular mediator of immune response GO:0002440 103 0.936
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.933
positive regulation of apoptotic process GO:0043065 217 0.925
meiotic cell cycle process GO:1903046 77 0.918
Worm Fly
double strand break repair via nonhomologous end joining GO:0006303 10 0.917
cell cycle checkpoint GO:0000075 47 0.898
somatic diversification of immunoglobulins GO:0016445 43 0.849
apoptotic signaling pathway GO:0097190 306 0.846
histone modification GO:0016570 159 0.816
Fly
adaptive immune response GO:0002250 155 0.783
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.769
cellular response to gamma radiation GO:0071480 4 0.755
Human
somatic cell dna recombination GO:0016444 51 0.743
blastocyst growth GO:0001832 23 0.743
immunoglobulin mediated immune response GO:0016064 69 0.743
lymphocyte mediated immunity GO:0002449 139 0.715
response to light stimulus GO:0009416 135 0.708
dna integrity checkpoint GO:0031570 28 0.705
stem cell differentiation GO:0048863 268 0.691
isotype switching GO:0045190 36 0.689
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.669
leukocyte activation involved in immune response GO:0002366 126 0.661
somatic recombination of t cell receptor gene segments GO:0002681 5 0.658
nuclear division GO:0000280 158 0.639
Human Worm
negative regulation of cell cycle GO:0045786 123 0.634
Human Fly
protein processing GO:0016485 163 0.626
Human
v d j recombination GO:0033151 14 0.623
response to gamma radiation GO:0010332 22 0.612
Human
positive regulation of histone h3 k4 methylation GO:0051571 5 0.611
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.599
Human Fly
positive regulation of cell death GO:0010942 224 0.590
leukocyte differentiation GO:0002521 342 0.579
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.575
immune effector process GO:0002252 321 0.573
negative regulation of dna dependent dna replication GO:2000104 1 0.562
negative regulation of cellular protein metabolic process GO:0032269 247 0.555
Human
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.538
dna damage checkpoint GO:0000077 26 0.530
b cell activation GO:0042113 161 0.526
cellular ketone metabolic process GO:0042180 84 0.510
intra s dna damage checkpoint GO:0031573 4 0.507
leukocyte mediated immunity GO:0002443 174 0.504
chromatin modification GO:0016568 187 0.504
Fly
negative regulation of mitotic cell cycle GO:0045930 58 0.495
Human Fly
negative regulation of protein metabolic process GO:0051248 282 0.475
Human
germ cell development GO:0007281 185 0.466
t cell receptor v d j recombination GO:0033153 5 0.461
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.451
peptidyl amino acid modification GO:0018193 336 0.450
Human
stem cell maintenance GO:0019827 130 0.446
stem cell development GO:0048864 219 0.440
blood vessel morphogenesis GO:0048514 285 0.437
regulation of cellular ketone metabolic process GO:0010565 66 0.437
nucleotide excision repair GO:0006289 13 0.437
b cell mediated immunity GO:0019724 71 0.429
dna replication GO:0006260 52 0.429
positive regulation of programmed cell death GO:0043068 218 0.428
somatic diversification of t cell receptor genes GO:0002568 5 0.426
regulation of cellular amine metabolic process GO:0033238 20 0.424
cellular amino acid metabolic process GO:0006520 103 0.418
negative regulation of protein modification process GO:0031400 163 0.403
mitotic sister chromatid cohesion GO:0007064 1 0.402
amine metabolic process GO:0009308 45 0.397
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 2 0.392
regulation of neuron apoptotic process GO:0043523 122 0.380
histone h3 acetylation GO:0043966 14 0.378
regulation of dna dependent dna replication GO:0090329 8 0.377
lymphocyte differentiation GO:0030098 242 0.358
regulation of cellular response to stress GO:0080135 159 0.357
Human
anatomical structure homeostasis GO:0060249 145 0.357
Fly
mitotic g2 dna damage checkpoint GO:0007095 8 0.346
Human Fly
negative regulation of cell cycle phase transition GO:1901988 48 0.341
Human Fly
histone h4 k16 acetylation GO:0043984 3 0.340
male meiosis i GO:0007141 16 0.339
negative regulation of cell cycle process GO:0010948 69 0.333
Human Fly
lymphocyte activation involved in immune response GO:0002285 93 0.326
gland development GO:0048732 330 0.320
meiotic chromosome segregation GO:0045132 19 0.320
Worm
telomere capping GO:0016233 4 0.317
Fly
signal transduction by p53 class mediator GO:0072331 51 0.313
Human
negative regulation of neuron death GO:1901215 98 0.306
Fly
blastocyst development GO:0001824 80 0.292
regulation of histone methylation GO:0031060 30 0.290
female gamete generation GO:0007292 74 0.288
b cell activation involved in immune response GO:0002312 50 0.284
regulation of apoptotic signaling pathway GO:2001233 197 0.282
organelle fission GO:0048285 170 0.268
Human Worm
cellular macromolecule catabolic process GO:0044265 206 0.255
Human Fly
response to uv GO:0009411 44 0.254
regulation of cell cycle process GO:0010564 160 0.254
Human Zebrafish Fly
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.251
Human
cell activation involved in immune response GO:0002263 126 0.250
regulation of mitotic cell cycle GO:0007346 126 0.247
Human Zebrafish Fly
peptidyl lysine modification GO:0018205 77 0.240
somatic diversification of immune receptors via somatic mutation GO:0002566 8 0.225
replication fork protection GO:0048478 1 0.221
dna dependent dna replication GO:0006261 24 0.218
epithelial cell proliferation GO:0050673 174 0.205
negative regulation of cellular amine metabolic process GO:0033239 1 0.203
epithelial tube morphogenesis GO:0060562 303 0.200
positive regulation of histone h3 k9 methylation GO:0051574 4 0.199
methylation GO:0032259 134 0.199
regulation of response to dna damage stimulus GO:2001020 34 0.198
Human
regulation of mitotic cell cycle phase transition GO:1901990 73 0.189
Human Zebrafish Fly
negative regulation of cell proliferation GO:0008285 296 0.184
Human
aromatic compound catabolic process GO:0019439 286 0.183
Human Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.183
regulation of chromatin modification GO:1903308 57 0.182
regulation of dna replication GO:0006275 17 0.182
meiosis i GO:0007127 60 0.182
regulation of histone h3 k4 methylation GO:0051569 12 0.179
positive regulation of histone methylation GO:0031062 16 0.171
neuron apoptotic process GO:0051402 142 0.170
protein modification by small protein conjugation or removal GO:0070647 207 0.167
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.164
hematopoietic progenitor cell differentiation GO:0002244 143 0.164
macromolecule methylation GO:0043414 120 0.161
meiotic nuclear division GO:0007126 115 0.159
Worm
negative regulation of mammary gland epithelial cell proliferation GO:0033600 3 0.149
oocyte maturation GO:0001556 18 0.148
purine ribonucleotide metabolic process GO:0009150 290 0.148
immunoglobulin v d j recombination GO:0033152 5 0.147
t cell differentiation in thymus GO:0033077 77 0.140
oocyte differentiation GO:0009994 35 0.140
histone h3 k4 methylation GO:0051568 23 0.140
macromolecule catabolic process GO:0009057 281 0.139
cellular amine metabolic process GO:0044106 44 0.136
cellular response to abiotic stimulus GO:0071214 56 0.133
Human
regulation of cell cycle GO:0051726 281 0.130
Human Zebrafish Fly
cell aging GO:0007569 35 0.129
Human
cell division GO:0051301 120 0.128
Human
female sex differentiation GO:0046660 84 0.128
intracellular signal transduction involved in g1 dna damage checkpoint GO:1902400 3 0.126
regulation of epithelial cell proliferation GO:0050678 141 0.125
purine containing compound metabolic process GO:0072521 311 0.125
t cell activation GO:0042110 289 0.125
skeletal system development GO:0001501 356 0.124
negative regulation of phosphorylation GO:0042326 166 0.124
regulation of cell cycle g2 m phase transition GO:1902749 10 0.123
Human Zebrafish
chromatin organization GO:0006325 206 0.123
Fly
negative regulation of phosphate metabolic process GO:0045936 184 0.121
regulation of lipid metabolic process GO:0019216 118 0.120
internal peptidyl lysine acetylation GO:0018393 42 0.118
heterocycle catabolic process GO:0046700 280 0.118
Human Fly
g1 s transition of mitotic cell cycle GO:0000082 57 0.117
cation transport GO:0006812 399 0.117
positive regulation of protein modification process GO:0031401 299 0.117
regulation of cellular component biogenesis GO:0044087 181 0.115
cellular response to organonitrogen compound GO:0071417 145 0.113
neuron death GO:0070997 154 0.112
signal transduction involved in dna damage checkpoint GO:0072422 3 0.110
Human
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.110
regulation of membrane potential GO:0042391 192 0.110
histone lysine methylation GO:0034968 50 0.108
positive regulation of apoptotic signaling pathway GO:2001235 95 0.108
b cell differentiation GO:0030183 78 0.108
reciprocal dna recombination GO:0035825 16 0.107
spermatogenesis GO:0007283 284 0.104
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.104
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.103
Human
centrosome organization GO:0051297 26 0.102
regulation of cell cycle phase transition GO:1901987 77 0.100
Human Zebrafish Fly
cell fate commitment GO:0045165 210 0.099
regulation of chromatin organization GO:1902275 57 0.099
cytokine production GO:0001816 319 0.098
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.098
positive regulation of nervous system development GO:0051962 221 0.098
internal protein amino acid acetylation GO:0006475 42 0.098
negative regulation of growth GO:0045926 99 0.098
histone h4 acetylation GO:0043967 10 0.096
regulation of mammary gland epithelial cell proliferation GO:0033599 12 0.095
positive regulation of cellular amine metabolic process GO:0033240 5 0.094
forebrain development GO:0030900 302 0.094
activation of cysteine type endopeptidase activity GO:0097202 27 0.094
regulation of protein transport GO:0051223 163 0.091
positive regulation of cell cycle process GO:0090068 61 0.090
cardiac muscle cell contraction GO:0086003 7 0.090
female gonad development GO:0008585 71 0.089
dna biosynthetic process GO:0071897 22 0.089
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.089
protein acylation GO:0043543 64 0.088
atp catabolic process GO:0006200 55 0.088
nucleoside monophosphate metabolic process GO:0009123 85 0.088
mitotic g1 dna damage checkpoint GO:0031571 4 0.088
regulation of neuron differentiation GO:0045664 281 0.088
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.086
negative regulation of neuron apoptotic process GO:0043524 92 0.086
nucleobase containing small molecule metabolic process GO:0055086 352 0.085
protein modification by small protein conjugation GO:0032446 187 0.084
protein autophosphorylation GO:0046777 61 0.084
Human
negative regulation of phosphorus metabolic process GO:0010563 184 0.084
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.082
Human
positive regulation of chromosome organization GO:2001252 33 0.082
cellular response to ionizing radiation GO:0071479 11 0.081
Human
protein methylation GO:0006479 81 0.080
morphogenesis of a branching epithelium GO:0061138 193 0.080
cell maturation GO:0048469 127 0.080
mitotic cell cycle process GO:1903047 159 0.079
Human Zebrafish Fly
response to purine containing compound GO:0014074 28 0.079
Fly
extrinsic apoptotic signaling pathway GO:0097191 126 0.078
angiogenesis GO:0001525 201 0.078
development of primary sexual characteristics GO:0045137 143 0.078
regulation of neuron death GO:1901214 134 0.076
positive regulation of growth GO:0045927 104 0.075
protein maturation GO:0051604 176 0.074
Human
positive regulation of chromatin modification GO:1903310 28 0.073
regulation of organelle organization GO:0033043 289 0.073
Human
regulation of kinase activity GO:0043549 249 0.071
cell type specific apoptotic process GO:0097285 268 0.071
dna conformation change GO:0071103 37 0.071
sensory perception of mechanical stimulus GO:0050954 107 0.071
keratinocyte differentiation GO:0030216 48 0.070
dna alkylation GO:0006305 43 0.069
cellular response to radiation GO:0071478 28 0.069
Human
inflammatory response GO:0006954 244 0.068
sister chromatid cohesion GO:0007062 12 0.067
intracellular protein transport GO:0006886 204 0.067
dna catabolic process GO:0006308 19 0.066
Fly
regulation of histone modification GO:0031056 56 0.066
bone development GO:0060348 120 0.065
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.064
regulation of innate immune response GO:0045088 91 0.064
Fly
mitotic cell cycle GO:0000278 195 0.064
Human Zebrafish Fly
reciprocal meiotic recombination GO:0007131 16 0.064
development of primary female sexual characteristics GO:0046545 73 0.063
positive regulation of cellular component biogenesis GO:0044089 94 0.063
multicellular organism growth GO:0035264 161 0.063
t cell differentiation GO:0030217 174 0.063
response to extracellular stimulus GO:0009991 127 0.062
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.062
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.062
Human
response to nutrient levels GO:0031667 109 0.059
calcium ion transport GO:0006816 159 0.058
neuron maturation GO:0042551 29 0.057
double strand break repair via homologous recombination GO:0000724 21 0.057
regulation of histone h3 k9 methylation GO:0051570 8 0.057
dna ligation GO:0006266 3 0.057
nucleoside phosphate metabolic process GO:0006753 338 0.057
circulatory system process GO:0003013 197 0.057
sensory organ morphogenesis GO:0090596 242 0.056
organic cyclic compound catabolic process GO:1901361 295 0.056
Human Fly
urogenital system development GO:0001655 261 0.056
dna duplex unwinding GO:0032508 7 0.056
regulation of organ morphogenesis GO:2000027 144 0.056
dna damage response signal transduction resulting in transcription GO:0042772 2 0.055
negative regulation of epithelial cell proliferation GO:0050680 64 0.055
cellular metal ion homeostasis GO:0006875 151 0.055
cellular ion homeostasis GO:0006873 165 0.055
response to transforming growth factor beta GO:0071559 88 0.055
histone acetylation GO:0016573 41 0.054
cellular nitrogen compound catabolic process GO:0044270 280 0.054
Human Fly
positive regulation of cell cycle GO:0045787 92 0.054
negative regulation of histone h3 k9 methylation GO:0051573 4 0.054
innate immune response GO:0045087 157 0.053
Fly
cellular response to inorganic substance GO:0071241 37 0.053
sensory perception of sound GO:0007605 97 0.053
ear development GO:0043583 200 0.052
limb development GO:0060173 166 0.052
oocyte development GO:0048599 33 0.051
nucleotide metabolic process GO:0009117 332 0.051
regulation of cell cycle g1 s phase transition GO:1902806 35 0.051
organophosphate biosynthetic process GO:0090407 122 0.051
Human
myeloid cell homeostasis GO:0002262 114 0.051
muscle contraction GO:0006936 101 0.051
ribonucleoside catabolic process GO:0042454 206 0.050
positive regulation of cytokine production GO:0001819 174 0.050
branching morphogenesis of an epithelial tube GO:0048754 159 0.050
glial cell apoptotic process GO:0034349 3 0.050
Fly
nucleoside phosphate catabolic process GO:1901292 222 0.050
regulation of chromosome organization GO:0033044 83 0.050
Human
regulation of chromatin silencing GO:0031935 2 0.050
glycosyl compound metabolic process GO:1901657 246 0.049
response to drug GO:0042493 75 0.049
generation of precursor metabolites and energy GO:0006091 103 0.049
fibroblast proliferation GO:0048144 35 0.048
positive regulation of histone modification GO:0031058 28 0.048
regulation of protein maturation GO:1903317 96 0.048
Human
somatic hypermutation of immunoglobulin genes GO:0016446 7 0.047
positive regulation of mitotic cell cycle GO:0045931 41 0.047
histone h4 k20 methylation GO:0034770 8 0.047
maintenance of location GO:0051235 89 0.046
lipid biosynthetic process GO:0008610 179 0.046
Human
base excision repair GO:0006284 9 0.045
apoptotic mitochondrial changes GO:0008637 48 0.045
cellular homeostasis GO:0019725 240 0.045
response to growth factor GO:0070848 198 0.045
embryonic organ morphogenesis GO:0048562 276 0.045
camera type eye development GO:0043010 266 0.045
purine nucleotide metabolic process GO:0006163 302 0.045
response to testosterone GO:0033574 3 0.045
regulation of protein kinase activity GO:0045859 232 0.044
positive regulation of transferase activity GO:0051347 167 0.044
ribonucleoside monophosphate metabolic process GO:0009161 80 0.044
response to heat GO:0009408 27 0.044
ribonucleotide metabolic process GO:0009259 291 0.043
protein ubiquitination GO:0016567 171 0.043
histone methylation GO:0016571 71 0.043
g2 dna damage checkpoint GO:0031572 8 0.042
Human Fly
negative regulation of molecular function GO:0044092 258 0.042
gene silencing GO:0016458 38 0.042
Fly
positive regulation of protein phosphorylation GO:0001934 242 0.041
response to lipopolysaccharide GO:0032496 128 0.041
mitochondrial dna repair GO:0043504 3 0.041
positive regulation of kinase activity GO:0033674 155 0.040
covalent chromatin modification GO:0016569 163 0.040
Fly
posttranscriptional regulation of gene expression GO:0010608 155 0.040
cell cycle arrest GO:0007050 37 0.040
Human
atp metabolic process GO:0046034 75 0.040
purine nucleoside triphosphate catabolic process GO:0009146 203 0.039
dendrite development GO:0016358 115 0.039
telomere maintenance in response to dna damage GO:0043247 4 0.039
negative regulation of apoptotic signaling pathway GO:2001234 104 0.039
negative regulation of histone methylation GO:0031061 10 0.039
recombinational repair GO:0000725 21 0.039
heart morphogenesis GO:0003007 178 0.039
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.039
Fly
protection from non homologous end joining at telomere GO:0031848 4 0.039
positive regulation of organelle organization GO:0010638 128 0.039
respiratory system development GO:0060541 190 0.038
lateral inhibition GO:0046331 1 0.038
positive regulation of hydrolase activity GO:0051345 148 0.038
somitogenesis GO:0001756 69 0.038
microtubule organizing center organization GO:0031023 28 0.038
purine containing compound catabolic process GO:0072523 213 0.037
dna methylation GO:0006306 43 0.037
regulation of defense response GO:0031347 233 0.037
Fly
regulation of meiotic cell cycle GO:0051445 34 0.037
positive regulation of neuron apoptotic process GO:0043525 25 0.037
skin development GO:0043588 220 0.037
posttranscriptional gene silencing GO:0016441 10 0.037
mapk cascade GO:0000165 281 0.036
purine nucleoside triphosphate metabolic process GO:0009144 226 0.036
sensory perception GO:0007600 245 0.036
positive regulation of defense response GO:0031349 124 0.036
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 18 0.036
bmp signaling pathway GO:0030509 93 0.036
lipid homeostasis GO:0055088 63 0.036
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.036
negative regulation of reactive oxygen species metabolic process GO:2000378 10 0.036
gonad development GO:0008406 141 0.035
positive regulation of peptidase activity GO:0010952 49 0.035
regulation of transferase activity GO:0051338 263 0.035
digestive system development GO:0055123 200 0.035
regulation of cell division GO:0051302 76 0.035
Human
regulation of establishment of protein localization GO:0070201 181 0.035
positive regulation of neuron differentiation GO:0045666 141 0.035
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.034
glycosyl compound catabolic process GO:1901658 206 0.034
spermatid differentiation GO:0048515 115 0.034
regulation of cytoplasmic transport GO:1903649 112 0.033
response to acid chemical GO:0001101 111 0.033
positive regulation of response to dna damage stimulus GO:2001022 14 0.033
Human
ubiquitin dependent protein catabolic process GO:0006511 129 0.033
Human
nucleoside triphosphate metabolic process GO:0009141 230 0.033
regulation of proteolysis GO:0030162 164 0.033
Human
purine nucleoside catabolic process GO:0006152 205 0.033
regulation of system process GO:0044057 200 0.033
positive regulation of protein autophosphorylation GO:0031954 4 0.033
positive regulation of cell development GO:0010720 237 0.032
cellular response to growth factor stimulus GO:0071363 197 0.032
peptidyl serine modification GO:0018209 83 0.032
Human
regulation of lipid biosynthetic process GO:0046890 54 0.032
carbohydrate metabolic process GO:0005975 230 0.032
regulation of fibroblast proliferation GO:0048145 34 0.032
negative regulation of gene expression epigenetic GO:0045814 15 0.032
Fly
neuroblast differentiation GO:0014016 2 0.032
histone h3 k9 methylation GO:0051567 17 0.032
central nervous system neuron differentiation GO:0021953 162 0.032
response to oxidative stress GO:0006979 123 0.032
regulation of neuron projection development GO:0010975 169 0.032
regulation of protein stability GO:0031647 52 0.031
somatic stem cell maintenance GO:0035019 47 0.031
regulation of nuclear cell cycle dna replication GO:0033262 2 0.031
mitotic cell cycle checkpoint GO:0007093 31 0.031
Human Fly
fat cell differentiation GO:0045444 160 0.030
embryonic limb morphogenesis GO:0030326 126 0.030
microtubule based process GO:0007017 236 0.030
nucleoside triphosphate catabolic process GO:0009143 205 0.030
negative regulation of chromatin silencing GO:0031936 1 0.030
retina development in camera type eye GO:0060041 119 0.030
cellular response to oxidative stress GO:0034599 76 0.030
ion transmembrane transport GO:0034220 361 0.030
organic hydroxy compound metabolic process GO:1901615 203 0.030
response to molecule of bacterial origin GO:0002237 143 0.030
positive regulation of mapk cascade GO:0043410 170 0.030
hindbrain development GO:0030902 128 0.029
respiratory tube development GO:0030323 167 0.029
glial cell differentiation GO:0010001 131 0.029
epithelial cell development GO:0002064 159 0.029
cellular response to lipid GO:0071396 145 0.029
regulation of intracellular transport GO:0032386 159 0.029
ossification GO:0001503 216 0.029
pallium development GO:0021543 120 0.029
positive regulation of neuron death GO:1901216 28 0.029
segmentation GO:0035282 93 0.028
spermatid development GO:0007286 108 0.028
neuromuscular process GO:0050905 99 0.028
regulation of multi organism process GO:0043900 111 0.028
negative regulation of cell cycle g1 s phase transition GO:1902807 18 0.028
signal transduction in response to dna damage GO:0042770 21 0.028
Human
somite development GO:0061053 81 0.028
regulation of homeostatic process GO:0032844 182 0.028
engulfment of apoptotic cell GO:0043652 3 0.028
protein targeting GO:0006605 143 0.027
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.027
compound eye development GO:0048749 1 0.027
neuromuscular process controlling balance GO:0050885 59 0.027
response to steroid hormone GO:0048545 56 0.027
negative regulation of cellular component organization GO:0051129 194 0.027
Human
genetic imprinting GO:0071514 27 0.027
dna geometric change GO:0032392 7 0.027
multicellular organismal aging GO:0010259 24 0.027
positive regulation of immune effector process GO:0002699 107 0.027
metal ion homeostasis GO:0055065 189 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.027
postreplication repair GO:0006301 5 0.027
inorganic cation transmembrane transport GO:0098662 207 0.027
negative regulation of protein phosphorylation GO:0001933 126 0.026
peptidyl lysine acetylation GO:0018394 45 0.026
cation homeostasis GO:0055080 212 0.026
gliogenesis GO:0042063 141 0.026
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 3 0.026
negative regulation of proteolysis GO:0045861 74 0.026
Human
regulation of circadian rhythm GO:0042752 58 0.026
negative regulation of cell development GO:0010721 169 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
organophosphate catabolic process GO:0046434 232 0.026
regulation of cytokine production GO:0001817 266 0.026
mesenchyme development GO:0060485 152 0.025
cardiac chamber development GO:0003205 108 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
mismatch repair GO:0006298 8 0.025
hepaticobiliary system development GO:0061008 67 0.025
regulation of peptidyl serine phosphorylation GO:0033135 39 0.025
modification dependent protein catabolic process GO:0019941 133 0.025
Human
wound healing GO:0042060 157 0.025
calcium ion homeostasis GO:0055074 127 0.025
cerebellum development GO:0021549 77 0.025
regulation of cellular catabolic process GO:0031329 242 0.024
Human
regulation of inositol phosphate biosynthetic process GO:0010919 3 0.024
response to osmotic stress GO:0006970 21 0.024
regionalization GO:0003002 337 0.024
second messenger mediated signaling GO:0019932 73 0.024
cardiac muscle tissue development GO:0048738 130 0.024
cellular chemical homeostasis GO:0055082 215 0.024
phenol containing compound metabolic process GO:0018958 60 0.024
embryonic appendage morphogenesis GO:0035113 126 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
cellular calcium ion homeostasis GO:0006874 119 0.024
morphogenesis of a branching structure GO:0001763 203 0.024
neural tube development GO:0021915 160 0.023
negative regulation of homeostatic process GO:0032845 71 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.023
b cell lineage commitment GO:0002326 4 0.023
developmental maturation GO:0021700 193 0.023
myeloid leukocyte differentiation GO:0002573 119 0.023
connective tissue development GO:0061448 179 0.023
regulation of heart contraction GO:0008016 77 0.023
mammary gland epithelium development GO:0061180 65 0.023

Atm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.971
Human
disease of cellular proliferation DOID:14566 0 0.971
Human
organ system cancer DOID:0050686 0 0.971
Human
immune system disease DOID:2914 0 0.556
disease of anatomical entity DOID:7 0 0.556
bone marrow disease DOID:4961 0 0.505
hematopoietic system disease DOID:74 0 0.505
immune system cancer DOID:0060083 0 0.437
hematologic cancer DOID:2531 0 0.437
endocrine gland cancer DOID:170 0 0.264
aplastic anemia DOID:12449 0 0.200
anemia DOID:2355 0 0.200
pancreatic cancer DOID:1793 0 0.161
thoracic cancer DOID:5093 0 0.130
Human
congenital hypoplastic anemia DOID:1342 0 0.106
leukemia DOID:1240 0 0.057
breast cancer DOID:1612 0 0.047
Human
reproductive organ cancer DOID:193 0 0.043