Mus musculus

25 known processes

Furin

furin (paired basic amino acid cleaving enzyme)

(Aliases: PACE,9130404I01Rik,Fur,SPC1,Pcsk3)

Furin biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell adhesion GO:0007155 329 0.284
cellular amino acid metabolic process GO:0006520 103 0.159
regulation of cellular amine metabolic process GO:0033238 20 0.134
regulation of cellular ketone metabolic process GO:0010565 66 0.122
regulation of secretion GO:0051046 274 0.118
regulation of defense response GO:0031347 233 0.116
leukocyte differentiation GO:0002521 342 0.099
regulation of cell motility GO:2000145 236 0.095
negative regulation of immune system process GO:0002683 209 0.088
response to molecule of bacterial origin GO:0002237 143 0.085
organonitrogen compound biosynthetic process GO:1901566 192 0.084
Human Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.082
extracellular structure organization GO:0043062 148 0.080
kidney development GO:0001822 213 0.080
Mouse
myeloid cell differentiation GO:0030099 233 0.077
positive regulation of protein modification process GO:0031401 299 0.074
negative regulation of protein metabolic process GO:0051248 282 0.074
Human
regulation of mapk cascade GO:0043408 248 0.073
negative regulation of cell proliferation GO:0008285 296 0.073
glycoprotein metabolic process GO:0009100 116 0.073
nitrogen compound transport GO:0071705 271 0.071
peptidyl amino acid modification GO:0018193 336 0.071
negative regulation of cellular protein metabolic process GO:0032269 247 0.070
Human
regulation of cellular catabolic process GO:0031329 242 0.069
Human
transmembrane transport GO:0055085 412 0.069
immune response regulating signaling pathway GO:0002764 125 0.067
regulation of cell adhesion GO:0030155 154 0.067
single organismal cell cell adhesion GO:0016337 131 0.067
muscle cell differentiation GO:0042692 261 0.066
regulation of intracellular transport GO:0032386 159 0.066
cytokine production GO:0001816 319 0.066
Human Mouse
regulation of cytokine production GO:0001817 266 0.066
Human
positive regulation of cellular amine metabolic process GO:0033240 5 0.065
negative regulation of phosphorus metabolic process GO:0010563 184 0.065
regulation of cell migration GO:0030334 219 0.064
single organism cell adhesion GO:0098602 156 0.063
regulation of cell activation GO:0050865 289 0.063
t cell activation GO:0042110 289 0.062
immune effector process GO:0002252 321 0.062
gland development GO:0048732 330 0.061
purine nucleotide metabolic process GO:0006163 302 0.061
negative regulation of cell activation GO:0050866 111 0.060
protein catabolic process GO:0030163 221 0.059
Human
cellular amide metabolic process GO:0043603 58 0.057
Human Mouse Worm
negative regulation of phosphate metabolic process GO:0045936 184 0.056
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.055
exocytosis GO:0006887 121 0.054
Mouse
response to organonitrogen compound GO:0010243 246 0.054
heterocycle catabolic process GO:0046700 280 0.053
regulation of cellular response to stress GO:0080135 159 0.053
mapk cascade GO:0000165 281 0.053
cellular ketone metabolic process GO:0042180 84 0.052
epidermis development GO:0008544 187 0.052
regulation of protein serine threonine kinase activity GO:0071900 157 0.051
regulation of hydrolase activity GO:0051336 246 0.051
Human
positive regulation of cell activation GO:0050867 158 0.050
lymphocyte differentiation GO:0030098 242 0.050
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.049
neuron migration GO:0001764 122 0.049
i kappab kinase nf kappab signaling GO:0007249 85 0.049
small gtpase mediated signal transduction GO:0007264 97 0.049
cell substrate adhesion GO:0031589 130 0.048
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.048
gastrulation GO:0007369 116 0.047
response to lipopolysaccharide GO:0032496 128 0.047
cellular nitrogen compound catabolic process GO:0044270 280 0.046
cellular response to organonitrogen compound GO:0071417 145 0.046
macromolecule catabolic process GO:0009057 281 0.046
Human
purine ribonucleoside metabolic process GO:0046128 241 0.046
posttranscriptional regulation of gene expression GO:0010608 155 0.046
immune response activating signal transduction GO:0002757 116 0.046
cellular response to cytokine stimulus GO:0071345 189 0.046
cytokine biosynthetic process GO:0042089 68 0.046
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.045
Human Mouse
intracellular protein transport GO:0006886 204 0.045
regulation of secretion by cell GO:1903530 249 0.045
endocytosis GO:0006897 168 0.044
regulation of organelle organization GO:0033043 289 0.044
regulation of organ morphogenesis GO:2000027 144 0.044
anion transport GO:0006820 177 0.044
inflammatory response GO:0006954 244 0.044
t cell differentiation GO:0030217 174 0.044
germ cell development GO:0007281 185 0.044
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.044
cellular chemical homeostasis GO:0055082 215 0.044
ras protein signal transduction GO:0007265 77 0.043
regionalization GO:0003002 337 0.043
Mouse
digestive tract development GO:0048565 190 0.043
Mouse
purine containing compound metabolic process GO:0072521 311 0.043
blood vessel morphogenesis GO:0048514 285 0.043
axonogenesis GO:0007409 274 0.042
organelle localization GO:0051640 179 0.042
nucleoside phosphate metabolic process GO:0006753 338 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.042
glucose homeostasis GO:0042593 128 0.042
purine nucleoside metabolic process GO:0042278 241 0.041
cation transport GO:0006812 399 0.041
regulation of ossification GO:0030278 112 0.041
spermatogenesis GO:0007283 284 0.041
Mouse
response to organic cyclic compound GO:0014070 198 0.041
glycoprotein biosynthetic process GO:0009101 89 0.041
carbohydrate metabolic process GO:0005975 230 0.040
protein maturation GO:0051604 176 0.040
activation of immune response GO:0002253 138 0.040
negative regulation of phosphorylation GO:0042326 166 0.039
ear development GO:0043583 200 0.039
cellular lipid metabolic process GO:0044255 323 0.039
skin development GO:0043588 220 0.038
stem cell differentiation GO:0048863 268 0.038
skeletal system development GO:0001501 356 0.038
Zebrafish Mouse
muscle tissue development GO:0060537 308 0.038
midgut development GO:0007494 4 0.038
apoptotic signaling pathway GO:0097190 306 0.038
carbohydrate derivative biosynthetic process GO:1901137 183 0.037
regulation of hormone levels GO:0010817 211 0.037
Human Mouse Worm
epithelial cell proliferation GO:0050673 174 0.037
ribonucleotide catabolic process GO:0009261 208 0.037
positive regulation of cell adhesion GO:0045785 80 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
cellular homeostasis GO:0019725 240 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
regulation of exocytosis GO:0017157 61 0.036
positive regulation of lymphocyte activation GO:0051251 140 0.036
regulation of leukocyte mediated immunity GO:0002703 104 0.036
binding of sperm to zona pellucida GO:0007339 34 0.036
Mouse
regulation of protein transport GO:0051223 163 0.036
positive regulation of cytokine production GO:0001819 174 0.036
response to radiation GO:0009314 165 0.035
striated muscle tissue development GO:0014706 293 0.035
amine metabolic process GO:0009308 45 0.035
response to endoplasmic reticulum stress GO:0034976 53 0.035
neuron death GO:0070997 154 0.035
dna metabolic process GO:0006259 303 0.035
positive regulation of programmed cell death GO:0043068 218 0.035
ossification GO:0001503 216 0.035
ribose phosphate metabolic process GO:0019693 291 0.035
nucleotide metabolic process GO:0009117 332 0.034
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.034
aromatic compound catabolic process GO:0019439 286 0.034
regulation of lymphocyte proliferation GO:0050670 117 0.034
rho protein signal transduction GO:0007266 32 0.034
myeloid leukocyte activation GO:0002274 83 0.034
regulation of multi organism process GO:0043900 111 0.034
regulation of response to wounding GO:1903034 189 0.034
purine containing compound catabolic process GO:0072523 213 0.034
nucleoside catabolic process GO:0009164 206 0.034
negative regulation of defense response GO:0031348 77 0.034
lung development GO:0030324 164 0.034
t cell differentiation in thymus GO:0033077 77 0.033
cellular amine metabolic process GO:0044106 44 0.033
myeloid leukocyte differentiation GO:0002573 119 0.033
innate immune response GO:0045087 157 0.033
t cell proliferation GO:0042098 120 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.033
respiratory system development GO:0060541 190 0.033
fertilization GO:0009566 127 0.032
Mouse
regulation of t cell activation GO:0050863 170 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
extracellular matrix organization GO:0030198 147 0.032
mammary gland lobule development GO:0061377 22 0.032
membrane organization GO:0061024 245 0.032
regulation of protein localization GO:0032880 231 0.032
protein modification by small protein conjugation GO:0032446 187 0.032
renal system development GO:0072001 225 0.032
Mouse
urogenital system development GO:0001655 261 0.032
Mouse
cellular response to dna damage stimulus GO:0006974 207 0.032
leukocyte mediated immunity GO:0002443 174 0.031
positive regulation of innate immune response GO:0045089 80 0.031
forebrain development GO:0030900 302 0.031
interspecies interaction between organisms GO:0044419 83 0.031
Human Mouse
positive regulation of defense response GO:0031349 124 0.031
spermatid differentiation GO:0048515 115 0.031
Mouse
male gamete generation GO:0048232 285 0.031
Mouse
lipid transport GO:0006869 98 0.031
glycosyl compound catabolic process GO:1901658 206 0.030
cellular response to organic cyclic compound GO:0071407 87 0.030
circulatory system process GO:0003013 197 0.030
appendage morphogenesis GO:0035107 149 0.030
Zebrafish Mouse
epithelial cell development GO:0002064 159 0.030
fat cell differentiation GO:0045444 160 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
leukocyte activation involved in immune response GO:0002366 126 0.029
negative regulation of protein modification process GO:0031400 163 0.029
lateral inhibition GO:0046331 1 0.029
actin cytoskeleton organization GO:0030036 220 0.029
negative regulation of molecular function GO:0044092 258 0.029
Human
multicellular organismal homeostasis GO:0048871 164 0.029
regulation of stress activated mapk cascade GO:0032872 69 0.028
cell activation involved in immune response GO:0002263 126 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.028
purine nucleotide catabolic process GO:0006195 211 0.028
embryonic placenta development GO:0001892 98 0.028
protein localization to cell junction GO:1902414 3 0.028
purine nucleoside triphosphate metabolic process GO:0009144 226 0.027
cytokine metabolic process GO:0042107 71 0.027
Mouse
peptidyl tyrosine modification GO:0018212 145 0.027
developmental maturation GO:0021700 193 0.027
Mouse
positive regulation of mapk cascade GO:0043410 170 0.027
regulation of establishment of protein localization GO:0070201 181 0.027
amide transport GO:0042886 138 0.027
nucleotide catabolic process GO:0009166 217 0.027
regulation of reproductive process GO:2000241 66 0.027
cell recognition GO:0008037 83 0.027
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.027
sulfur compound metabolic process GO:0006790 100 0.026
positive regulation of immune effector process GO:0002699 107 0.026
cell fate commitment GO:0045165 210 0.026
cellular response to biotic stimulus GO:0071216 92 0.026
positive regulation of cell migration GO:0030335 109 0.026
ion transmembrane transport GO:0034220 361 0.026
cellular macromolecule catabolic process GO:0044265 206 0.026
Human
cellular response to hormone stimulus GO:0032870 150 0.026
limb development GO:0060173 166 0.026
Mouse
camera type eye development GO:0043010 266 0.026
mitochondrion organization GO:0007005 134 0.026
cardiocyte differentiation GO:0035051 87 0.026
immunoglobulin production GO:0002377 73 0.026
regulation of transferase activity GO:0051338 263 0.026
cation homeostasis GO:0055080 212 0.026
negative regulation of cellular component organization GO:0051129 194 0.026
stress activated mapk cascade GO:0051403 80 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.025
defense response to other organism GO:0098542 197 0.025
cytoplasmic transport GO:0016482 234 0.025
mitotic cell cycle process GO:1903047 159 0.025
cellular response to lipid GO:0071396 145 0.025
regulation of wnt signaling pathway GO:0030111 123 0.025
embryonic organ morphogenesis GO:0048562 276 0.025
Zebrafish
cell junction assembly GO:0034329 52 0.025
neuronal action potential GO:0019228 54 0.025
myeloid cell activation involved in immune response GO:0002275 34 0.024
hormone metabolic process GO:0042445 86 0.024
Human Mouse Worm
lipid localization GO:0010876 126 0.024
protein autophosphorylation GO:0046777 61 0.024
regulation of leukocyte differentiation GO:1902105 159 0.024
regulation of mast cell activation GO:0033003 21 0.024
spermatid development GO:0007286 108 0.024
Mouse
hormone secretion GO:0046879 128 0.024
blood circulation GO:0008015 195 0.024
hindbrain development GO:0030902 128 0.024
negative regulation of protein phosphorylation GO:0001933 126 0.024
regulation of inflammatory response GO:0050727 147 0.024
regulation of alpha beta t cell activation GO:0046634 53 0.024
skeletal muscle organ development GO:0060538 163 0.024
regulation of membrane potential GO:0042391 192 0.023
protein localization to organelle GO:0033365 185 0.023
leukocyte degranulation GO:0043299 27 0.023
peptidyl tyrosine phosphorylation GO:0018108 143 0.023
glycerolipid metabolic process GO:0046486 122 0.023
cellular protein complex assembly GO:0043623 116 0.023
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.023
regulation of map kinase activity GO:0043405 120 0.023
morphogenesis of a branching structure GO:0001763 203 0.023
lipid biosynthetic process GO:0008610 179 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
detection of stimulus GO:0051606 84 0.022
organelle fission GO:0048285 170 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
regulation of protein kinase activity GO:0045859 232 0.022
rhythmic process GO:0048511 174 0.022
regulation of epithelial cell proliferation GO:0050678 141 0.022
translation GO:0006412 93 0.022
smoothened signaling pathway GO:0007224 105 0.022
regulation of kinase activity GO:0043549 249 0.022
nucleoside metabolic process GO:0009116 246 0.022
negative regulation of interleukin 10 secretion GO:2001180 2 0.022
negative regulation of multi organism process GO:0043901 68 0.022
insulin secretion GO:0030073 89 0.021
peptide secretion GO:0002790 114 0.021
leukocyte proliferation GO:0070661 172 0.021
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.021
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
oxidation reduction process GO:0055114 342 0.021
central nervous system neuron differentiation GO:0021953 162 0.021
regulation of neuron differentiation GO:0045664 281 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
positive regulation of cellular catabolic process GO:0031331 148 0.021
wnt signaling pathway GO:0016055 188 0.021
rna interference GO:0016246 2 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
morphogenesis of a branching epithelium GO:0061138 193 0.021
negative regulation of t cell activation GO:0050868 65 0.021
positive regulation of cell motility GO:2000147 116 0.021
endomembrane system organization GO:0010256 147 0.021
establishment of planar polarity GO:0001736 28 0.021
gonad development GO:0008406 141 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
negative regulation of immune effector process GO:0002698 55 0.020
regulation of actin filament based process GO:0032970 99 0.020
lymphocyte mediated immunity GO:0002449 139 0.020
localization within membrane GO:0051668 4 0.020
connective tissue development GO:0061448 179 0.020
Zebrafish
organic anion transport GO:0015711 137 0.020
metencephalon development GO:0022037 89 0.020
cell cell recognition GO:0009988 44 0.020
Mouse
multicellular organismal signaling GO:0035637 91 0.020
multi multicellular organism process GO:0044706 109 0.020
Mouse
protein localization to membrane GO:0072657 108 0.020
cell maturation GO:0048469 127 0.020
Mouse
response to oxidative stress GO:0006979 123 0.020
intrinsic apoptotic signaling pathway GO:0097193 132 0.020
alpha beta t cell activation GO:0046631 91 0.019
wound healing GO:0042060 157 0.019
organic hydroxy compound transport GO:0015850 93 0.019
carboxylic acid transport GO:0046942 100 0.019
compound eye development GO:0048749 1 0.019
carbohydrate homeostasis GO:0033500 128 0.019
peptide transport GO:0015833 133 0.019
digestive system development GO:0055123 200 0.019
Mouse
odontogenesis of dentin containing tooth GO:0042475 66 0.019
cellular protein catabolic process GO:0044257 155 0.019
Human
regulation of innate immune response GO:0045088 91 0.019
negative regulation of lymphocyte activation GO:0051250 91 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
lymphocyte activation involved in immune response GO:0002285 93 0.019
neural tube development GO:0021915 160 0.019
cellular divalent inorganic cation homeostasis GO:0072503 127 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
detection of external stimulus GO:0009581 61 0.019
extrinsic apoptotic signaling pathway GO:0097191 126 0.019
myosin filament assembly GO:0031034 2 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
nephron development GO:0072006 109 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
peptide metabolic process GO:0006518 46 0.019
Human Mouse Worm
cytokine mediated signaling pathway GO:0019221 115 0.019
cardiac muscle tissue development GO:0048738 130 0.019
regulation of interleukin 6 production GO:0032675 55 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
locomotory behavior GO:0007626 195 0.019
odontogenesis GO:0042476 78 0.019
regulation of neuron apoptotic process GO:0043523 122 0.018
adaptive immune response GO:0002250 155 0.018
tissue homeostasis GO:0001894 115 0.018
chemotaxis GO:0006935 247 0.018
cellular ion homeostasis GO:0006873 165 0.018
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.018
regulation of t cell proliferation GO:0042129 92 0.018
actin filament organization GO:0007015 113 0.018
interleukin 6 production GO:0032635 58 0.018
cellular response to acid chemical GO:0071229 68 0.018
organic acid transport GO:0015849 101 0.018
positive regulation of intracellular transport GO:0032388 70 0.018
negative regulation of ossification GO:0030279 49 0.018
defense response to bacterium GO:0042742 119 0.018
establishment of tissue polarity GO:0007164 28 0.018
b cell activation GO:0042113 161 0.018
vesicle organization GO:0016050 60 0.018
organophosphate catabolic process GO:0046434 232 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
cellular response to inorganic substance GO:0071241 37 0.018
sensory organ morphogenesis GO:0090596 242 0.018
cellular calcium ion homeostasis GO:0006874 119 0.018
response to growth factor GO:0070848 198 0.018
digestive tract morphogenesis GO:0048546 147 0.018
respiratory tube development GO:0030323 167 0.017
Mouse
lymphocyte proliferation GO:0046651 164 0.017
production of molecular mediator of immune response GO:0002440 103 0.017
cellular response to peptide hormone stimulus GO:0071375 92 0.017
male sex differentiation GO:0046661 109 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
limb morphogenesis GO:0035108 149 0.017
Mouse
steroid metabolic process GO:0008202 119 0.017
establishment of organelle localization GO:0051656 122 0.017
regulated secretory pathway GO:0045055 32 0.017
peptide hormone secretion GO:0030072 109 0.017
placenta development GO:0001890 140 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
dephosphorylation GO:0016311 129 0.017
cellular response to extracellular stimulus GO:0031668 81 0.017
development of primary sexual characteristics GO:0045137 143 0.017
positive regulation of homeostatic process GO:0032846 64 0.017
regulation of peptide transport GO:0090087 91 0.017
mesenchyme development GO:0060485 152 0.017
nuclear transport GO:0051169 139 0.017
cardiac cell fate specification GO:0060912 2 0.017
organelle assembly GO:0070925 177 0.017
negative regulation of kinase activity GO:0033673 81 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.017
receptor mediated endocytosis GO:0006898 51 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
positive regulation of cell development GO:0010720 237 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
interleukin 8 production GO:0032637 4 0.017
protein targeting GO:0006605 143 0.017
osteoclast differentiation GO:0030316 62 0.017
regulation of interleukin 8 production GO:0032677 3 0.016
viral life cycle GO:0019058 36 0.016
Human Mouse
cerebral cortex development GO:0021987 86 0.016
cellular response to amino acid stimulus GO:0071230 29 0.016
protein autoprocessing GO:0016540 2 0.016
Mouse
response to amino acid GO:0043200 37 0.016
regulation of b cell activation GO:0050864 81 0.016
sulfur compound biosynthetic process GO:0044272 37 0.016
cation transmembrane transport GO:0098655 266 0.016
sterol metabolic process GO:0016125 58 0.016
cell cell junction organization GO:0045216 72 0.016
regulation of anatomical structure size GO:0090066 178 0.016
regulation of removal of superoxide radicals GO:2000121 4 0.016
regulation of ion transport GO:0043269 215 0.016
b cell mediated immunity GO:0019724 71 0.016
angiogenesis GO:0001525 201 0.016
modification dependent protein catabolic process GO:0019941 133 0.016
synapse organization GO:0050808 125 0.016
regulation of interleukin 10 secretion GO:2001179 4 0.016
cellular response to lipopolysaccharide GO:0071222 77 0.016
regulation of binding GO:0051098 111 0.016
heart morphogenesis GO:0003007 178 0.016
protein processing GO:0016485 163 0.016
stem cell proliferation GO:0072089 117 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.016
mammary gland alveolus development GO:0060749 22 0.016
maintenance of location GO:0051235 89 0.016
glycerolipid biosynthetic process GO:0045017 50 0.016
calcium ion homeostasis GO:0055074 127 0.016
positive regulation of transferase activity GO:0051347 167 0.016
brain segmentation GO:0035284 3 0.016
cellularization GO:0007349 1 0.015
guanosine containing compound catabolic process GO:1901069 144 0.015
protein glycosylation GO:0006486 55 0.015
mast cell activation GO:0045576 27 0.015
cognition GO:0050890 149 0.015
cell type specific apoptotic process GO:0097285 268 0.015
response to insulin GO:0032868 100 0.015
negative regulation of intracellular transport GO:0032387 38 0.015
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
vacuole organization GO:0007033 38 0.015
jnk cascade GO:0007254 72 0.015
heart contraction GO:0060047 93 0.015
innate immune response activating signal transduction GO:0002758 50 0.015
regulation of cellular response to growth factor stimulus GO:0090287 82 0.015
body morphogenesis GO:0010171 45 0.015
cardiac muscle cell differentiation GO:0055007 69 0.015
development of primary male sexual characteristics GO:0046546 88 0.015
nuclear import GO:0051170 95 0.015
keratinocyte migration GO:0051546 3 0.015
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.015
endocrine system development GO:0035270 98 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
b cell differentiation GO:0030183 78 0.015
viral process GO:0016032 41 0.015
Human Mouse
forebrain cell migration GO:0021885 58 0.015
regulation of hormone secretion GO:0046883 88 0.015
microtubule based process GO:0007017 236 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.015
regulation of cardioblast differentiation GO:0051890 3 0.015
stem cell development GO:0048864 219 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
interleukin 13 secretion GO:0072611 2 0.015
telencephalon cell migration GO:0022029 55 0.015
skeletal system morphogenesis GO:0048705 203 0.015
Zebrafish
regulation of cytokine secretion GO:0050707 61 0.015
neuron projection guidance GO:0097485 141 0.014
synaptic transmission GO:0007268 329 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
positive regulation of secretion GO:0051047 130 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
interleukin 10 secretion GO:0072608 4 0.014
regulation of translation GO:0006417 71 0.014
protein ubiquitination GO:0016567 171 0.014
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.014
adult behavior GO:0030534 135 0.014
defense response to gram negative bacterium GO:0050829 28 0.014
mitotic cell cycle GO:0000278 195 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
glycosylation GO:0070085 62 0.014
regulation of body fluid levels GO:0050878 162 0.014
cellular response to molecule of bacterial origin GO:0071219 83 0.014
plasma membrane organization GO:0007009 90 0.014
positive regulation of cellular component biogenesis GO:0044089 94 0.014
mesenchymal cell development GO:0014031 93 0.014
regulation of cell cycle GO:0051726 281 0.014
positive regulation of secretion by cell GO:1903532 114 0.014

Furin disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.094
inherited metabolic disorder DOID:655 0 0.053
disease of anatomical entity DOID:7 0 0.043
cardiovascular system disease DOID:1287 0 0.043
sensory system disease DOID:0050155 0 0.024
nervous system disease DOID:863 0 0.024
muscular disease DOID:0080000 0 0.023
musculoskeletal system disease DOID:17 0 0.023
myopathy DOID:423 0 0.018
heart disease DOID:114 0 0.018
cardiomyopathy DOID:0050700 0 0.018
muscle tissue disease DOID:66 0 0.018
neuropathy DOID:870 0 0.018