Mus musculus

119 known processes

Klrk1

killer cell lectin-like receptor subfamily K, member 1

(Aliases: Nkg2d,D6H12S2489E,NKG2-D)

Klrk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of natural killer cell mediated immunity GO:0002717 16 1.000
stimulatory c type lectin receptor signaling pathway GO:0002223 2 1.000
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.997
response to molecule of fungal origin GO:0002238 4 0.995
Mouse
detection of fungus GO:0016046 2 0.994
Mouse
regulation of innate immune response GO:0045088 91 0.990
detection of yeast GO:0001879 2 0.990
Mouse
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.984
cytokine production GO:0001816 319 0.976
leukocyte mediated immunity GO:0002443 174 0.974
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.974
Mouse
natural killer cell mediated immunity GO:0002228 29 0.973
regulation of leukocyte mediated immunity GO:0002703 104 0.966
lymphocyte mediated immunity GO:0002449 139 0.966
innate immune response GO:0045087 157 0.958
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.952
positive regulation of defense response GO:0031349 124 0.952
regulation of defense response GO:0031347 233 0.949
detection of other organism GO:0098543 8 0.948
Mouse
positive regulation of cell killing GO:0031343 33 0.948
defense response to other organism GO:0098542 197 0.945
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.943
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.937
leukocyte mediated cytotoxicity GO:0001909 62 0.933
cell killing GO:0001906 67 0.933
regulation of lymphocyte mediated immunity GO:0002706 84 0.924
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.918
natural killer cell mediated cytotoxicity GO:0042267 29 0.917
myeloid cell differentiation GO:0030099 233 0.913
Mouse
activation of innate immune response GO:0002218 56 0.905
response to molecule of bacterial origin GO:0002237 143 0.893
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.886
regulation of natural killer cell mediated immunity GO:0002715 19 0.885
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.884
positive regulation of leukocyte mediated immunity GO:0002705 70 0.883
positive regulation of tumor necrosis factor production GO:0032760 30 0.876
Mouse
positive regulation of innate immune response GO:0045089 80 0.871
interferon gamma production GO:0032609 67 0.866
positive regulation of immune effector process GO:0002699 107 0.865
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.863
positive regulation of t cell costimulation GO:2000525 2 0.834
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.816
Mouse
eosinophil activation GO:0043307 1 0.814
regulation of lymphocyte activation GO:0051249 240 0.813
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.811
Mouse
positive regulation of cytokine production GO:0001819 174 0.810
regulation of interferon gamma production GO:0032649 57 0.810
adaptive immune response GO:0002250 155 0.802
natural killer cell activation GO:0030101 44 0.792
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.790
Mouse
regulation of cytokine production GO:0001817 266 0.787
positive regulation of interferon gamma production GO:0032729 39 0.784
immune response activating signal transduction GO:0002757 116 0.779
alpha beta t cell activation GO:0046631 91 0.775
negative regulation of immune system process GO:0002683 209 0.768
activation of immune response GO:0002253 138 0.750
mature dendritic cell differentiation GO:0097029 3 0.749
immune effector process GO:0002252 321 0.741
negative regulation of eosinophil degranulation GO:0043310 1 0.732
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.731
eosinophil activation involved in immune response GO:0002278 1 0.728
positive regulation of monocyte chemotaxis GO:0090026 2 0.719
immune response regulating signaling pathway GO:0002764 125 0.713
response to lipopolysaccharide GO:0032496 128 0.705
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.699
defense response to gram positive bacterium GO:0050830 50 0.693
negative regulation of homeostatic process GO:0032845 71 0.676
positive regulation of immunological synapse formation GO:2000522 1 0.671
cytokine mediated signaling pathway GO:0019221 115 0.670
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.670
antigen processing and presentation GO:0019882 47 0.664
cell activation involved in immune response GO:0002263 126 0.661
Mouse
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.661
negative regulation of macrophage apoptotic process GO:2000110 3 0.656
regulation of ion homeostasis GO:2000021 64 0.654
regulation of cell killing GO:0031341 40 0.652
interleukin 12 secretion GO:0072610 3 0.651
cell recognition GO:0008037 83 0.651
Mouse
regulation of t cell costimulation GO:2000523 2 0.627
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.625
tumor necrosis factor production GO:0032640 50 0.625
Mouse
positive regulation of lymphocyte activation GO:0051251 140 0.620
leukocyte differentiation GO:0002521 342 0.617
cellular response to lipopolysaccharide GO:0071222 77 0.601
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.589
regulation of tumor necrosis factor production GO:0032680 49 0.583
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.581
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.562
eosinophil degranulation GO:0043308 1 0.552
defense response to bacterium GO:0042742 119 0.549
regulation of cell activation GO:0050865 289 0.545
regulation of monocyte chemotaxis GO:0090025 3 0.543
microglial cell activation involved in immune response GO:0002282 1 0.540
cell chemotaxis GO:0060326 81 0.538
t helper 17 cell chemotaxis GO:0035705 1 0.531
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.527
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.525
myeloid cell apoptotic process GO:0033028 22 0.522
regulation of reactive oxygen species metabolic process GO:2000377 40 0.521
positive regulation of lymphocyte proliferation GO:0050671 70 0.520
monocyte extravasation GO:0035696 2 0.519
leukocyte proliferation GO:0070661 172 0.514
helper t cell chemotaxis GO:0035704 1 0.503
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.500
regulation of nitric oxide biosynthetic process GO:0045428 18 0.479
leukocyte activation involved in immune response GO:0002366 126 0.478
Mouse
positive regulation of inflammatory response GO:0050729 47 0.472
t cell extravasation GO:0072683 4 0.467
reactive oxygen species biosynthetic process GO:1903409 8 0.467
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.464
regulation of eosinophil degranulation GO:0043309 1 0.462
regulation of t cell extravasation GO:2000407 3 0.458
chemokine mediated signaling pathway GO:0070098 17 0.457
regulation of immunological synapse formation GO:2000520 2 0.456
regulation of phagocytosis GO:0050764 33 0.453
Mouse
cellular response to biotic stimulus GO:0071216 92 0.453
regulation of dendritic cell chemotaxis GO:2000508 1 0.442
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.442
innate immune response activating signal transduction GO:0002758 50 0.434
regulation of adaptive immune response GO:0002819 90 0.429
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.424
regulation of secretion GO:0051046 274 0.417
positive regulation of t cell extravasation GO:2000409 2 0.410
t cell differentiation GO:0030217 174 0.398
reactive oxygen species metabolic process GO:0072593 84 0.391
t cell proliferation GO:0042098 120 0.390
detection of biotic stimulus GO:0009595 10 0.385
Mouse
positive regulation of neutrophil migration GO:1902624 12 0.376
t cell migration GO:0072678 19 0.376
positive regulation of monocyte extravasation GO:2000439 1 0.372
regulation of alpha beta t cell proliferation GO:0046640 18 0.367
positive regulation of t cell activation GO:0050870 101 0.364
t cell activation GO:0042110 289 0.360
negative regulation of innate immune response GO:0045824 17 0.360
positive regulation of phagocytosis GO:0050766 26 0.359
Mouse
immune complex clearance by monocytes and macrophages GO:0002436 2 0.358
regulation of cytokine biosynthetic process GO:0042035 59 0.352
positive regulation of b cell mediated immunity GO:0002714 26 0.351
cytokine secretion GO:0050663 72 0.349
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.348
calcium ion homeostasis GO:0055074 127 0.344
disruption by host of symbiont cells GO:0051852 11 0.341
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.339
macrophage activation GO:0042116 27 0.338
sequestering of calcium ion GO:0051208 18 0.334
release of sequestered calcium ion into cytosol GO:0051209 42 0.334
mapk cascade GO:0000165 281 0.333
regulation of vesicle mediated transport GO:0060627 139 0.332
Mouse
hematopoietic stem cell migration GO:0035701 1 0.330
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.329
regulation of type 2 immune response GO:0002828 18 0.326
negative regulation of leukocyte mediated immunity GO:0002704 29 0.326
g protein coupled receptor signaling pathway GO:0007186 243 0.321
interleukin 1 beta production GO:0032611 30 0.321
alpha beta t cell proliferation GO:0046633 21 0.321
myeloid leukocyte differentiation GO:0002573 119 0.309
positive regulation of secretion GO:0051047 130 0.308
myeloid leukocyte activation GO:0002274 83 0.308
regulation of t cell activation GO:0050863 170 0.307
immune complex clearance GO:0002434 2 0.307
reactive nitrogen species metabolic process GO:2001057 0 0.307
regulation of secretion by cell GO:1903530 249 0.302
angiogenesis GO:0001525 201 0.300
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.298
cellular response to molecule of bacterial origin GO:0071219 83 0.295
regulation of angiogenesis GO:0045765 81 0.291
myeloid leukocyte mediated immunity GO:0002444 42 0.290
regulation of establishment of protein localization GO:0070201 181 0.280
eosinophil mediated immunity GO:0002447 1 0.279
leukocyte chemotaxis GO:0030595 69 0.277
cellular response to lipid GO:0071396 145 0.274
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.273
negative regulation of multi organism process GO:0043901 68 0.265
sequestering of metal ion GO:0051238 19 0.262
granulocyte chemotaxis GO:0071621 39 0.259
regulation of t cell proliferation GO:0042129 92 0.258
negative regulation of growth of symbiont in host GO:0044130 19 0.254
nitric oxide metabolic process GO:0046209 25 0.254
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.253
nitric oxide biosynthetic process GO:0006809 25 0.249
positive regulation of adaptive immune response GO:0002821 61 0.248
t cell mediated cytotoxicity GO:0001913 26 0.243
lymphocyte differentiation GO:0030098 242 0.242
t helper 1 type immune response GO:0042088 25 0.241
regulation of vasculature development GO:1901342 88 0.238
cellular response to molecule of fungal origin GO:0071226 2 0.238
Mouse
membrane invagination GO:0010324 17 0.237
Mouse
positive regulation of granulocyte chemotaxis GO:0071624 12 0.236
neutrophil migration GO:1990266 37 0.230
regulation of protein localization GO:0032880 231 0.228
microglial cell activation GO:0001774 3 0.225
lymphocyte migration GO:0072676 26 0.223
regulation of homeostatic process GO:0032844 182 0.222
regulation of regulated secretory pathway GO:1903305 20 0.221
regulation of angiotensin metabolic process GO:0060177 4 0.218
extrinsic apoptotic signaling pathway GO:0097191 126 0.217
acute inflammatory response GO:0002526 41 0.216
interleukin 1 beta secretion GO:0050702 16 0.215
response to yeast GO:0001878 6 0.213
Mouse
blood vessel morphogenesis GO:0048514 285 0.213
interleukin 1 production GO:0032612 31 0.210
regulation of cell migration GO:0030334 219 0.207
membrane organization GO:0061024 245 0.200
Mouse
negative regulation of immune effector process GO:0002698 55 0.198
cell type specific apoptotic process GO:0097285 268 0.197
regulation of endocytosis GO:0030100 69 0.195
Mouse
endocytosis GO:0006897 168 0.194
Mouse
regulation of hematopoietic stem cell migration GO:2000471 1 0.192
regulation of cytokine secretion GO:0050707 61 0.187
lymphocyte proliferation GO:0046651 164 0.186
regulation of intracellular transport GO:0032386 159 0.184
cytosolic calcium ion homeostasis GO:0051480 70 0.183
positive regulation of behavior GO:0048520 40 0.182
inflammatory response GO:0006954 244 0.182
positive regulation of chemotaxis GO:0050921 38 0.181
regulation of angiotensin levels in blood GO:0002002 4 0.181
positive regulation of cell activation GO:0050867 158 0.180
positive regulation of leukocyte differentiation GO:1902107 86 0.180
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.179
glycoprotein biosynthetic process GO:0009101 89 0.179
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.178
regulation of antigen processing and presentation GO:0002577 10 0.178
cytokine metabolic process GO:0042107 71 0.176
b cell mediated immunity GO:0019724 71 0.175
regulation of mapk cascade GO:0043408 248 0.171
cellular response to drug GO:0035690 15 0.170
Mouse
regulation of monocyte extravasation GO:2000437 2 0.170
neutrophil mediated cytotoxicity GO:0070942 8 0.169
regulation of epithelial cell proliferation GO:0050678 141 0.167
single organismal cell cell adhesion GO:0016337 131 0.165
Mouse
positive regulation of cell migration GO:0030335 109 0.162
regulation of protein transport GO:0051223 163 0.159
regulation of macrophage activation GO:0043030 17 0.158
defense response to virus GO:0051607 68 0.157
calcium ion transport into cytosol GO:0060402 48 0.157
regulation of leukocyte proliferation GO:0070663 121 0.151
killing of cells of other organism GO:0031640 13 0.151
interleukin 2 production GO:0032623 33 0.147
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.144
epithelial tube morphogenesis GO:0060562 303 0.143
positive regulation of leukocyte proliferation GO:0070665 73 0.142
regulation of neutrophil chemotaxis GO:0090022 14 0.142
cytosolic calcium ion transport GO:0060401 48 0.142
pattern recognition receptor signaling pathway GO:0002221 47 0.141
Mouse
apoptotic signaling pathway GO:0097190 306 0.141
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.140
positive regulation of endocytosis GO:0045807 42 0.139
Mouse
t cell costimulation GO:0031295 14 0.138
interleukin 12 production GO:0032615 32 0.137
dendritic cell chemotaxis GO:0002407 7 0.136
positive regulation of cytokine biosynthetic process GO:0042108 40 0.136
positive regulation of glycoprotein metabolic process GO:1903020 6 0.135
regulation of lymphocyte proliferation GO:0050670 117 0.135
microglia differentiation GO:0014004 2 0.135
type 2 immune response GO:0042092 23 0.133
regulation of cytoplasmic transport GO:1903649 112 0.133
regulation of chemotaxis GO:0050920 53 0.131
regulation of immunoglobulin mediated immune response GO:0002889 37 0.130
granulocyte migration GO:0097530 43 0.128
rho protein signal transduction GO:0007266 32 0.126
regulation of vascular endothelial growth factor production GO:0010574 13 0.125
phagocytosis GO:0006909 66 0.124
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.124
regulation of myoblast differentiation GO:0045661 29 0.123
regulation of neutrophil migration GO:1902622 14 0.123
regulation of protein secretion GO:0050708 82 0.122
leukocyte apoptotic process GO:0071887 71 0.122
neutrophil chemotaxis GO:0030593 36 0.121
t cell receptor signaling pathway GO:0050852 46 0.121
protein secretion GO:0009306 111 0.120
b cell activation GO:0042113 161 0.120
i kappab kinase nf kappab signaling GO:0007249 85 0.119
chemotaxis GO:0006935 247 0.119
cation homeostasis GO:0055080 212 0.119
response to interferon gamma GO:0034341 34 0.119
positive regulation of interleukin 12 production GO:0032735 21 0.118
tumor necrosis factor biosynthetic process GO:0042533 10 0.118
small gtpase mediated signal transduction GO:0007264 97 0.118
regulation of t helper 1 type immune response GO:0002825 17 0.113
regulation of blood pressure GO:0008217 93 0.113
positive regulation of t cell chemotaxis GO:0010820 5 0.113
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.113
metal ion homeostasis GO:0055065 189 0.112
granulocyte activation GO:0036230 10 0.111
regulation of apoptotic signaling pathway GO:2001233 197 0.111
cytoplasmic transport GO:0016482 234 0.110
regulation of hormone levels GO:0010817 211 0.110
cellular calcium ion homeostasis GO:0006874 119 0.109
positive regulation of alpha beta t cell activation GO:0046635 39 0.109
regulation of cell motility GO:2000145 236 0.109
ras protein signal transduction GO:0007265 77 0.107
divalent inorganic cation transport GO:0072511 178 0.106
interaction with symbiont GO:0051702 14 0.106
negative regulation of cell activation GO:0050866 111 0.106
regulation of cellular ketone metabolic process GO:0010565 66 0.105
positive regulation of t helper 1 type immune response GO:0002827 12 0.105
signal transduction in absence of ligand GO:0038034 55 0.105
regulation of leukocyte apoptotic process GO:2000106 56 0.102
positive regulation of secretion by cell GO:1903532 114 0.102
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.101
regulation of acute inflammatory response GO:0002673 27 0.101
dendritic cell antigen processing and presentation GO:0002468 7 0.100
dendritic cell differentiation GO:0097028 26 0.100
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.100
humoral immune response GO:0006959 57 0.099
t cell activation involved in immune response GO:0002286 43 0.099
regulation of humoral immune response GO:0002920 22 0.099
interspecies interaction between organisms GO:0044419 83 0.099
negative regulation of angiogenesis GO:0016525 25 0.098
regulation of cellular amine metabolic process GO:0033238 20 0.097
negative regulation of vasculature development GO:1901343 26 0.096
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.096
regulation of natural killer cell activation GO:0032814 22 0.095
positive regulation of programmed cell death GO:0043068 218 0.094
cellular ion homeostasis GO:0006873 165 0.094
myeloid leukocyte migration GO:0097529 57 0.093
t cell chemotaxis GO:0010818 6 0.093
cell cell recognition GO:0009988 44 0.092
positive regulation of macrophage activation GO:0043032 10 0.091
t cell mediated immunity GO:0002456 50 0.091
carbohydrate derivative biosynthetic process GO:1901137 183 0.091
positive regulation of apoptotic process GO:0043065 217 0.091
morphogenesis of a branching epithelium GO:0061138 193 0.090
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.090
detection of external biotic stimulus GO:0098581 9 0.090
Mouse
antigen receptor mediated signaling pathway GO:0050851 64 0.089
cellular homeostasis GO:0019725 240 0.088
production of molecular mediator of immune response GO:0002440 103 0.087
disruption of cells of other organism GO:0044364 13 0.087
inflammatory response to antigenic stimulus GO:0002437 30 0.087
cellular amine metabolic process GO:0044106 44 0.085
positive regulation of intracellular transport GO:0032388 70 0.085
positive regulation of homeostatic process GO:0032846 64 0.085
divalent inorganic cation homeostasis GO:0072507 138 0.083
regulation of multi organism process GO:0043900 111 0.083
sensory perception GO:0007600 245 0.083
negative regulation of intracellular signal transduction GO:1902532 167 0.082
myelination GO:0042552 74 0.082
positive regulation of cell death GO:0010942 224 0.082
morphogenesis of a branching structure GO:0001763 203 0.082
regulation of interleukin 12 production GO:0032655 30 0.081
negative regulation of growth GO:0045926 99 0.080
regulation of interleukin 2 production GO:0032663 28 0.080
positive regulation of thymocyte migration GO:2000412 2 0.078
regulation of cellular amino acid metabolic process GO:0006521 5 0.078
divalent metal ion transport GO:0070838 172 0.078
glycoprotein metabolic process GO:0009100 116 0.078
regulation of b cell mediated immunity GO:0002712 37 0.077
neutrophil mediated killing of symbiont cell GO:0070943 8 0.077
regulation of interleukin 1 production GO:0032652 26 0.077
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.077
negative thymic t cell selection GO:0045060 12 0.077
natural killer cell inhibitory signaling pathway GO:0002769 2 0.077
cellular defense response GO:0006968 6 0.077
cell adhesion GO:0007155 329 0.077
Mouse
interleukin 18 mediated signaling pathway GO:0035655 2 0.076
lymphocyte costimulation GO:0031294 15 0.076
phagocytosis recognition GO:0006910 12 0.075
Mouse
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.074
regulation of exocytosis GO:0017157 61 0.074
regulation of alpha beta t cell activation GO:0046634 53 0.074
regulation of granulocyte chemotaxis GO:0071622 17 0.073
cellular divalent inorganic cation homeostasis GO:0072503 127 0.073
regulation of b cell activation GO:0050864 81 0.073
positive regulation of angiogenesis GO:0045766 46 0.072
killing by host of symbiont cells GO:0051873 11 0.072
eosinophil migration GO:0072677 3 0.072
regulation of protein import into nucleus GO:0042306 52 0.072
positive regulation of response to wounding GO:1903036 66 0.072
regulation of immunoglobulin production GO:0002637 42 0.071
antigen processing and presentation of exogenous antigen GO:0019884 26 0.071
positive regulation of antigen processing and presentation GO:0002579 10 0.071
negative regulation of natural killer cell mediated immunity GO:0002716 5 0.070
homeostasis of number of cells GO:0048872 210 0.070
oxidation reduction process GO:0055114 342 0.070
positive regulation of glial cell differentiation GO:0045687 21 0.070
macrophage apoptotic process GO:0071888 7 0.069
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.069
interleukin 6 production GO:0032635 58 0.069
amine metabolic process GO:0009308 45 0.068
positive regulation of neutrophil chemotaxis GO:0090023 12 0.067
lymphocyte activation involved in immune response GO:0002285 93 0.067
second messenger mediated signaling GO:0019932 73 0.066
natural killer cell chemotaxis GO:0035747 1 0.065
regulation of purine nucleotide metabolic process GO:1900542 169 0.065
positive regulation of humoral immune response GO:0002922 11 0.065
response to organic cyclic compound GO:0014070 198 0.065
positive regulation of acute inflammatory response GO:0002675 16 0.065
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.065
macrophage chemotaxis GO:0048246 14 0.064
regulation of t cell mediated immunity GO:0002709 34 0.064
anion transport GO:0006820 177 0.064
cytokine biosynthetic process GO:0042089 68 0.063
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.063
multicellular organismal homeostasis GO:0048871 164 0.062
peptidyl amino acid modification GO:0018193 336 0.062
vascular endothelial growth factor production GO:0010573 13 0.062
regulation of myeloid cell apoptotic process GO:0033032 19 0.062
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.062
regulation of leukocyte differentiation GO:1902105 159 0.062
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.061
negative regulation of blood vessel morphogenesis GO:2000181 25 0.061
negative regulation of apoptotic signaling pathway GO:2001234 104 0.061
regulation of acute inflammatory response to antigenic stimulus GO:0002864 10 0.060
growth of symbiont in host GO:0044117 23 0.060
positive regulation of interferon alpha production GO:0032727 4 0.060
regulation of interleukin 1 beta production GO:0032651 25 0.059
inflammatory cell apoptotic process GO:0006925 11 0.059
regulation of growth of symbiont in host GO:0044126 19 0.058
cellular extravasation GO:0045123 17 0.058
lymph node development GO:0048535 18 0.057
negative regulation of regulated secretory pathway GO:1903306 7 0.057
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.057
growth involved in symbiotic interaction GO:0044110 23 0.056
lymphocyte chemotaxis GO:0048247 10 0.056
myeloid cell activation involved in immune response GO:0002275 34 0.056
positive regulation of acute inflammatory response to antigenic stimulus GO:0002866 7 0.055
intracellular protein transport GO:0006886 204 0.054
negative regulation of myeloid cell apoptotic process GO:0033033 11 0.054
leukocyte migration GO:0050900 124 0.053
negative t cell selection GO:0043383 13 0.053
immunoglobulin mediated immune response GO:0016064 69 0.053
regulation of interleukin 1 beta secretion GO:0050706 15 0.052
regulation of lymphocyte migration GO:2000401 14 0.052
regulation of response to cytokine stimulus GO:0060759 23 0.052
cellular ketone metabolic process GO:0042180 84 0.052
positive regulation of protein transport GO:0051222 93 0.052
modification by host of symbiont morphology or physiology GO:0051851 12 0.052
positive regulation of t cell proliferation GO:0042102 52 0.052
monocyte chemotaxis GO:0002548 5 0.051
platelet morphogenesis GO:0036344 13 0.051
Mouse
positive regulation of t cell migration GO:2000406 10 0.051
regulation of rho protein signal transduction GO:0035023 71 0.050
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.050
regulation of inflammatory response GO:0050727 147 0.050
negative regulation of secretion GO:0051048 61 0.050
leukocyte degranulation GO:0043299 27 0.049
single organism cell adhesion GO:0098602 156 0.049
Mouse
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.049
response to organonitrogen compound GO:0010243 246 0.049
regulation of t cell receptor signaling pathway GO:0050856 21 0.049
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.048
positive regulation of mapk cascade GO:0043410 170 0.048
cellular response to interleukin 18 GO:0071351 3 0.048
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.048
ameboidal type cell migration GO:0001667 128 0.047
forebrain development GO:0030900 302 0.047
positive regulation of protein localization to nucleus GO:1900182 30 0.047
protein localization to nucleus GO:0034504 121 0.047
thymic t cell selection GO:0045061 22 0.046
maintenance of location GO:0051235 89 0.046
tissue remodeling GO:0048771 102 0.046
growth of symbiont involved in interaction with host GO:0044116 23 0.046
neutrophil mediated killing of bacterium GO:0070944 6 0.046
regulation of membrane potential GO:0042391 192 0.045
positive regulation of lymphocyte migration GO:2000403 11 0.045
t cell differentiation involved in immune response GO:0002292 30 0.045
negative regulation of interferon gamma production GO:0032689 18 0.045
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.045
acute inflammatory response to antigenic stimulus GO:0002438 12 0.045
regulation of glycoprotein biosynthetic process GO:0010559 12 0.045
cerebral cortex cell migration GO:0021795 44 0.045
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.045
endocrine process GO:0050886 39 0.044
regulation of response to wounding GO:1903034 189 0.044
multicellular organismal signaling GO:0035637 91 0.044
regulation of interleukin 1 secretion GO:0050704 15 0.043
t cell selection GO:0045058 34 0.043
positive regulation of cell development GO:0010720 237 0.042
positive regulation of eosinophil migration GO:2000418 2 0.042
branching morphogenesis of an epithelial tube GO:0048754 159 0.042
positive regulation of cell motility GO:2000147 116 0.042
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.042
positive regulation of camp mediated signaling GO:0043950 3 0.041
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.041
nucleotide metabolic process GO:0009117 332 0.041
cellular response to interferon beta GO:0035458 21 0.041
positive regulation of t cell differentiation GO:0045582 52 0.041
positive regulation of cytoplasmic transport GO:1903651 40 0.040
nucleoside phosphate metabolic process GO:0006753 338 0.040
ensheathment of neurons GO:0007272 76 0.040
t cell differentiation in thymus GO:0033077 77 0.040
regulation of myeloid cell differentiation GO:0045637 96 0.040
chemokine production GO:0032602 34 0.040
regulation of nucleotide metabolic process GO:0006140 169 0.040
calcium ion transport GO:0006816 159 0.040
cellular response to growth factor stimulus GO:0071363 197 0.039
regulation of nucleocytoplasmic transport GO:0046822 73 0.039
tissue homeostasis GO:0001894 115 0.039
negative regulation of defense response GO:0031348 77 0.039
positive regulation of jnk cascade GO:0046330 46 0.039
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.039
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.039
peptidyl tyrosine phosphorylation GO:0018108 143 0.038
cdc42 protein signal transduction GO:0032488 0 0.038
regulation of systemic arterial blood pressure GO:0003073 61 0.038
regulation of lymphocyte chemotaxis GO:1901623 6 0.038
regulation of lymphocyte differentiation GO:0045619 107 0.038
response to growth factor GO:0070848 198 0.038
regulation of protein kinase activity GO:0045859 232 0.038

Klrk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org