Mus musculus

80 known processes

Pik3cb

phosphatidylinositol 3-kinase, catalytic, beta polypeptide

(Aliases: p110beta,1110001J02Rik,AI447572,MGC150132)

Pik3cb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid phosphorylation GO:0046834 25 0.896
phosphatidylinositol phosphorylation GO:0046854 23 0.803
regulation of kinase activity GO:0043549 249 0.633
Mouse
rho protein signal transduction GO:0007266 32 0.628
glycerophospholipid biosynthetic process GO:0046474 32 0.618
guanosine containing compound metabolic process GO:1901068 144 0.597
glycerolipid biosynthetic process GO:0045017 50 0.530
nucleoside phosphate metabolic process GO:0006753 338 0.499
guanosine containing compound catabolic process GO:1901069 144 0.498
small gtpase mediated signal transduction GO:0007264 97 0.487
regulation of cellular amine metabolic process GO:0033238 20 0.485
regulation of cellular ketone metabolic process GO:0010565 66 0.483
nucleobase containing small molecule metabolic process GO:0055086 352 0.448
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.435
Fly
purine nucleotide metabolic process GO:0006163 302 0.432
regulation of protein kinase activity GO:0045859 232 0.429
Mouse
phosphatidylinositol 3 phosphate biosynthetic process GO:0036092 6 0.423
cellular lipid metabolic process GO:0044255 323 0.419
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.419
cell adhesion GO:0007155 329 0.413
organic cyclic compound catabolic process GO:1901361 295 0.406
dna metabolic process GO:0006259 303 0.405
Mouse
gtp catabolic process GO:0006184 143 0.390
negative regulation of zinc ion transmembrane transport GO:0071583 2 0.351
Mouse
phospholipid metabolic process GO:0006644 87 0.347
purine ribonucleotide metabolic process GO:0009150 290 0.344
nucleotide metabolic process GO:0009117 332 0.343
regulation of ras protein signal transduction GO:0046578 114 0.341
organophosphate biosynthetic process GO:0090407 122 0.340
purine nucleoside triphosphate metabolic process GO:0009144 226 0.340
regulation of hydrolase activity GO:0051336 246 0.335
lipid biosynthetic process GO:0008610 179 0.329
rac protein signal transduction GO:0016601 13 0.324
cellular amino acid metabolic process GO:0006520 103 0.317
regulation of zinc ion transmembrane transport GO:0071580 2 0.315
Mouse
ribonucleotide catabolic process GO:0009261 208 0.307
ribonucleotide metabolic process GO:0009259 291 0.306
nucleoside metabolic process GO:0009116 246 0.303
ribose phosphate metabolic process GO:0019693 291 0.299
cellular ketone metabolic process GO:0042180 84 0.291
nucleoside phosphate catabolic process GO:1901292 222 0.290
phosphatidylinositol metabolic process GO:0046488 45 0.285
regulation of purine nucleotide metabolic process GO:1900542 169 0.280
amine metabolic process GO:0009308 45 0.278
purine nucleoside triphosphate catabolic process GO:0009146 203 0.276
response to organonitrogen compound GO:0010243 246 0.275
glycosyl compound metabolic process GO:1901657 246 0.274
organonitrogen compound catabolic process GO:1901565 264 0.273
glycosyl compound catabolic process GO:1901658 206 0.268
purine nucleotide catabolic process GO:0006195 211 0.266
organophosphate catabolic process GO:0046434 232 0.260
ribonucleoside catabolic process GO:0042454 206 0.259
positive regulation of protein kinase activity GO:0045860 144 0.258
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.255
glycerolipid metabolic process GO:0046486 122 0.249
nucleoside triphosphate catabolic process GO:0009143 205 0.248
regulation of mitotic cell cycle GO:0007346 126 0.245
Fly
ribonucleoside triphosphate catabolic process GO:0009203 199 0.241
mapk cascade GO:0000165 281 0.239
purine ribonucleotide catabolic process GO:0009154 208 0.230
regulation of ras gtpase activity GO:0032318 88 0.221
ribonucleoside triphosphate metabolic process GO:0009199 220 0.217
intracellular protein transport GO:0006886 204 0.206
developmental maturation GO:0021700 193 0.197
Fly
regulation of cell migration GO:0030334 219 0.195
positive regulation of jnk cascade GO:0046330 46 0.193
cellular response to dna damage stimulus GO:0006974 207 0.191
glucose metabolic process GO:0006006 92 0.185
Mouse
negative regulation of zinc ion transport GO:0071582 2 0.184
Mouse
aromatic compound catabolic process GO:0019439 286 0.184
cell type specific apoptotic process GO:0097285 268 0.183
Mouse
lipid modification GO:0030258 65 0.181
regulation of transferase activity GO:0051338 263 0.180
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.180
glycerophospholipid metabolic process GO:0006650 71 0.180
phospholipid biosynthetic process GO:0008654 36 0.180
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.179
negative regulation of immune system process GO:0002683 209 0.179
carbohydrate derivative catabolic process GO:1901136 231 0.178
g protein coupled receptor signaling pathway GO:0007186 243 0.178
regulation of lipid metabolic process GO:0019216 118 0.177
purine ribonucleoside metabolic process GO:0046128 241 0.176
purine nucleoside metabolic process GO:0042278 241 0.176
purine ribonucleoside catabolic process GO:0046130 205 0.176
ribonucleoside metabolic process GO:0009119 245 0.175
regulation of purine nucleotide catabolic process GO:0033121 122 0.175
purine containing compound metabolic process GO:0072521 311 0.173
engulfment of apoptotic cell GO:0043652 3 0.171
macromolecule catabolic process GO:0009057 281 0.170
nucleoside triphosphate metabolic process GO:0009141 230 0.170
leukocyte differentiation GO:0002521 342 0.166
regulation of cellular amino acid metabolic process GO:0006521 5 0.165
regulation of ion transport GO:0043269 215 0.163
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.161
ras protein signal transduction GO:0007265 77 0.157
positive regulation of mapk cascade GO:0043410 170 0.154
muscle cell differentiation GO:0042692 261 0.153
positive regulation of stress activated mapk cascade GO:0032874 48 0.153
regulation of protein serine threonine kinase activity GO:0071900 157 0.152
regulation of gtp catabolic process GO:0033124 113 0.150
ion transmembrane transport GO:0034220 361 0.150
Mouse
negative regulation of cell proliferation GO:0008285 296 0.144
cell substrate adhesion GO:0031589 130 0.138
regulation of exit from mitosis GO:0007096 1 0.137
homeostasis of number of cells GO:0048872 210 0.135
Mouse
heterocycle catabolic process GO:0046700 280 0.134
neuron apoptotic process GO:0051402 142 0.131
Mouse
keratinocyte development GO:0003334 10 0.129
gland development GO:0048732 330 0.129
Fly
regulation of nucleoside metabolic process GO:0009118 130 0.128
regulation of mapk cascade GO:0043408 248 0.123
purine containing compound catabolic process GO:0072523 213 0.123
positive regulation of ras gtpase activity GO:0032320 65 0.122
regulation of rho gtpase activity GO:0032319 58 0.119
inorganic ion transmembrane transport GO:0098660 234 0.119
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.118
synaptic transmission GO:0007268 329 0.117
Fly
stress activated protein kinase signaling cascade GO:0031098 81 0.115
nucleoside catabolic process GO:0009164 206 0.115
epithelial cell development GO:0002064 159 0.115
cellular response to organonitrogen compound GO:0071417 145 0.115
regulation of organelle organization GO:0033043 289 0.114
purine nucleoside catabolic process GO:0006152 205 0.114
cellular amine metabolic process GO:0044106 44 0.113
nucleotide catabolic process GO:0009166 217 0.112
myeloid cell differentiation GO:0030099 233 0.111
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.111
cellular response to radiation GO:0071478 28 0.110
regulation of cell cycle process GO:0010564 160 0.109
regulation of neuron apoptotic process GO:0043523 122 0.108
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.106
cytokine production GO:0001816 319 0.106
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.105
nucleotide biosynthetic process GO:0009165 78 0.105
myeloid leukocyte differentiation GO:0002573 119 0.105
keratinocyte differentiation GO:0030216 48 0.103
monosaccharide metabolic process GO:0005996 106 0.103
Mouse
jnk cascade GO:0007254 72 0.102
protein targeting GO:0006605 143 0.101
cellular response to lipid GO:0071396 145 0.101
regulation of chemotaxis GO:0050920 53 0.099
Worm
oxidation reduction process GO:0055114 342 0.099
inorganic cation transmembrane transport GO:0098662 207 0.098
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.096
carbohydrate metabolic process GO:0005975 230 0.096
Mouse Fly
circulatory system process GO:0003013 197 0.095
b cell activation GO:0042113 161 0.095
Mouse
actin cytoskeleton organization GO:0030036 220 0.093
protein autophosphorylation GO:0046777 61 0.092
regulation of cell motility GO:2000145 236 0.092
regulation of cytokine production GO:0001817 266 0.092
ribose phosphate biosynthetic process GO:0046390 59 0.092
regulation of cell adhesion GO:0030155 154 0.091
regulation of erk1 and erk2 cascade GO:0070372 71 0.090
b cell differentiation GO:0030183 78 0.090
regulation of cellular response to stress GO:0080135 159 0.090
cellular calcium ion homeostasis GO:0006874 119 0.089
transmembrane transport GO:0055085 412 0.089
Mouse
positive regulation of cell development GO:0010720 237 0.088
cellular response to abiotic stimulus GO:0071214 56 0.087
regulation of nucleotide metabolic process GO:0006140 169 0.087
response to radiation GO:0009314 165 0.087
mitotic cell cycle GO:0000278 195 0.086
Fly
regulation of rho protein signal transduction GO:0035023 71 0.086
regulation of peptidyl serine phosphorylation GO:0033135 39 0.085
Mouse
cell growth GO:0016049 130 0.085
response to growth factor GO:0070848 198 0.084
membrane invagination GO:0010324 17 0.083
regulation of cell substrate adhesion GO:0010810 73 0.082
positive regulation of kinase activity GO:0033674 155 0.082
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.081
Mouse
positive regulation of cell migration GO:0030335 109 0.081
positive regulation of protein phosphorylation GO:0001934 242 0.081
Mouse
peptidyl serine modification GO:0018209 83 0.081
Mouse
positive regulation of protein modification process GO:0031401 299 0.081
Mouse
oocyte axis specification GO:0007309 2 0.080
regulation of lipid kinase activity GO:0043550 14 0.080
cell division GO:0051301 120 0.080
cellular ion homeostasis GO:0006873 165 0.079
protein ubiquitination GO:0016567 171 0.078
lymphocyte homeostasis GO:0002260 64 0.078
Mouse
regulation of jnk cascade GO:0046328 62 0.077
positive regulation of map kinase activity GO:0043406 84 0.077
membrane organization GO:0061024 245 0.076
cellular response to insulin stimulus GO:0032869 78 0.076
protein localization to organelle GO:0033365 185 0.076
regulation of map kinase activity GO:0043405 120 0.075
regulation of leukocyte differentiation GO:1902105 159 0.075
divalent inorganic cation homeostasis GO:0072507 138 0.075
organonitrogen compound biosynthetic process GO:1901566 192 0.075
epithelial cell proliferation GO:0050673 174 0.074
protein modification by small protein conjugation or removal GO:0070647 207 0.073
phagocytosis GO:0006909 66 0.072
positive regulation of programmed cell death GO:0043068 218 0.072
negative regulation of phosphate metabolic process GO:0045936 184 0.072
cytoplasmic transport GO:0016482 234 0.072
stress activated mapk cascade GO:0051403 80 0.072
positive regulation of transferase activity GO:0051347 167 0.072
Mouse
microtubule based process GO:0007017 236 0.072
positive regulation of cell motility GO:2000147 116 0.071
cellular protein catabolic process GO:0044257 155 0.071
wnt signaling pathway GO:0016055 188 0.071
positive regulation of gtp catabolic process GO:0033126 85 0.071
regulation of proteolysis GO:0030162 164 0.070
nitrogen compound transport GO:0071705 271 0.070
regulation of metal ion transport GO:0010959 106 0.070
Mouse
gtp metabolic process GO:0046039 144 0.069
peptidyl amino acid modification GO:0018193 336 0.069
Mouse
regulation of neuron death GO:1901214 134 0.069
Mouse
response to osmotic stress GO:0006970 21 0.069
muscle tissue development GO:0060537 308 0.069
phosphatidylinositol biosynthetic process GO:0006661 15 0.068
regulation of neuron differentiation GO:0045664 281 0.068
Fly
regulation of transmembrane transport GO:0034762 128 0.068
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.068
protein catabolic process GO:0030163 221 0.068
regulation of genetic imprinting GO:2000653 5 0.067
Mouse
leukocyte migration GO:0050900 124 0.067
skin development GO:0043588 220 0.067
regionalization GO:0003002 337 0.066
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.066
purine containing compound biosynthetic process GO:0072522 70 0.066
regulation of cell projection organization GO:0031344 206 0.066
Fly
response to nutrient levels GO:0031667 109 0.066
Fly
b cell homeostasis GO:0001782 34 0.065
Mouse
regulation of myeloid leukocyte differentiation GO:0002761 58 0.064
oocyte construction GO:0007308 2 0.064
innate immune response GO:0045087 157 0.063
regulation of cellular catabolic process GO:0031329 242 0.063
Fly
cell matrix adhesion GO:0007160 68 0.063
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.062
positive regulation of apoptotic process GO:0043065 217 0.062
negative regulation of cellular protein metabolic process GO:0032269 247 0.061
carbohydrate derivative biosynthetic process GO:1901137 183 0.061
regulation of lamellipodium assembly GO:0010591 3 0.060
neuron death GO:0070997 154 0.060
Mouse
regulation of lymphocyte activation GO:0051249 240 0.060
coagulation GO:0050817 78 0.060
regulation of cellular component biogenesis GO:0044087 181 0.060
regulation of body fluid levels GO:0050878 162 0.060
regulation of blood pressure GO:0008217 93 0.059
cation transmembrane transport GO:0098655 266 0.059
Mouse
axonogenesis GO:0007409 274 0.059
regulation of nuclear division GO:0051783 56 0.057
cell junction maintenance GO:0034331 4 0.057
regulation of stress activated mapk cascade GO:0032872 69 0.057
response to light stimulus GO:0009416 135 0.057
metal ion homeostasis GO:0055065 189 0.057
regulation of actin filament based process GO:0032970 99 0.057
regulation of response to wounding GO:1903034 189 0.056
myotube differentiation GO:0014902 105 0.056
immune effector process GO:0002252 321 0.055
regulation of cellular component size GO:0032535 121 0.055
Fly
establishment or maintenance of cell polarity GO:0007163 86 0.055
cell fate commitment GO:0045165 210 0.055
anion transport GO:0006820 177 0.055
regulation of homeostatic process GO:0032844 182 0.055
protein processing GO:0016485 163 0.055
posttranscriptional regulation of gene expression GO:0010608 155 0.054
Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.054
regulation of intracellular protein transport GO:0033157 82 0.054
regulation of cytoplasmic transport GO:1903649 112 0.054
regulation of cell size GO:0008361 72 0.054
Fly
cellular divalent inorganic cation homeostasis GO:0072503 127 0.053
cellular response to hormone stimulus GO:0032870 150 0.053
negative regulation of fibroblast apoptotic process GO:2000270 6 0.053
Mouse
heart contraction GO:0060047 93 0.053
cellular response to peptide hormone stimulus GO:0071375 92 0.053
blood circulation GO:0008015 195 0.053
zinc ion transport GO:0006829 12 0.052
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.052
cellular carbohydrate metabolic process GO:0044262 119 0.052
macromolecule methylation GO:0043414 120 0.052
Mouse
regulation of anatomical structure size GO:0090066 178 0.052
Fly
leukocyte activation involved in immune response GO:0002366 126 0.051
protein kinase b signaling GO:0043491 74 0.050
Mouse
peptidyl tyrosine modification GO:0018212 145 0.050
cation transport GO:0006812 399 0.050
Mouse
positive regulation of gtpase activity GO:0043547 85 0.050
activation of adenylate cyclase activity GO:0007190 4 0.050
camp biosynthetic process GO:0006171 31 0.050
regulation of synaptic plasticity GO:0048167 87 0.049
Fly
positive regulation of neuron projection development GO:0010976 79 0.049
purine ribonucleotide biosynthetic process GO:0009152 59 0.049
embryonic organ morphogenesis GO:0048562 276 0.049
modification dependent protein catabolic process GO:0019941 133 0.049
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.049
cell junction organization GO:0034330 77 0.048
cognition GO:0050890 149 0.048
Worm
positive regulation of intracellular protein transport GO:0090316 42 0.048
cyclic nucleotide biosynthetic process GO:0009190 44 0.048
regulation of rac protein signal transduction GO:0035020 19 0.048
nucleocytoplasmic transport GO:0006913 139 0.048
localization within membrane GO:0051668 4 0.047
regulation of protein processing GO:0070613 96 0.047
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.047
regulation of protein catabolic process GO:0042176 108 0.047
ephrin receptor signaling pathway GO:0048013 20 0.047
asymmetric neuroblast division GO:0055059 1 0.047
lateral inhibition GO:0046331 1 0.046
blood coagulation GO:0007596 76 0.046
cellular chemical homeostasis GO:0055082 215 0.046
cellular response to external stimulus GO:0071496 88 0.046
Fly
platelet activation GO:0030168 40 0.046
lymphocyte differentiation GO:0030098 242 0.046
ubiquitin dependent protein catabolic process GO:0006511 129 0.045
protein import GO:0017038 101 0.045
dna alkylation GO:0006305 43 0.045
Mouse
asymmetric stem cell division GO:0098722 3 0.045
establishment of organelle localization GO:0051656 122 0.045
sensory perception GO:0007600 245 0.045
protein localization to nucleus GO:0034504 121 0.045
canonical wnt signaling pathway GO:0060070 130 0.045
protein modification by small protein conjugation GO:0032446 187 0.045
syncytium formation by plasma membrane fusion GO:0000768 42 0.044
calcium ion homeostasis GO:0055074 127 0.044
response to organic cyclic compound GO:0014070 198 0.044
cellular homeostasis GO:0019725 240 0.044
regulation of protein stability GO:0031647 52 0.044
cell chemotaxis GO:0060326 81 0.043
response to peptide hormone GO:0043434 127 0.043
telencephalon development GO:0021537 186 0.043
exocyst localization GO:0051601 2 0.043
cation homeostasis GO:0055080 212 0.043
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.043
Mouse
positive regulation of cytokine production GO:0001819 174 0.042
carbon catabolite activation of transcription GO:0045991 4 0.042
hexose metabolic process GO:0019318 98 0.042
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.042
negative regulation of cell cycle GO:0045786 123 0.042
endomembrane system organization GO:0010256 147 0.042
regulation of vesicle mediated transport GO:0060627 139 0.042
insulin receptor signaling pathway GO:0008286 49 0.042
germ cell development GO:0007281 185 0.042
Fly
inflammatory response GO:0006954 244 0.042
nuclear transport GO:0051169 139 0.041
organelle fission GO:0048285 170 0.041
positive regulation of cell projection organization GO:0031346 95 0.041
positive regulation of cell death GO:0010942 224 0.041
regulation of dna methylation GO:0044030 12 0.040
Mouse
negative regulation of cellular component organization GO:0051129 194 0.040
cellular response to light stimulus GO:0071482 19 0.040
regulation of cytoskeleton organization GO:0051493 122 0.040
heart process GO:0003015 94 0.040
leukocyte chemotaxis GO:0030595 69 0.040
autophagy GO:0006914 45 0.039
Fly
cell fate determination GO:0001709 32 0.039
positive regulation of response to wounding GO:1903036 66 0.039
negative regulation of anoikis GO:2000811 2 0.039
myeloid leukocyte migration GO:0097529 57 0.039
peptidyl serine phosphorylation GO:0018105 74 0.038
Mouse
regulation of secretion GO:0051046 274 0.038
synapse organization GO:0050808 125 0.038
Fly
response to uv GO:0009411 44 0.038
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.037
extrinsic apoptotic signaling pathway GO:0097191 126 0.037
positive regulation of protein export from nucleus GO:0046827 4 0.037
nucleoside phosphate biosynthetic process GO:1901293 79 0.037
skeletal system development GO:0001501 356 0.037
regulation of synapse structural plasticity GO:0051823 4 0.037
Fly
methylation GO:0032259 134 0.037
Mouse
leukocyte mediated immunity GO:0002443 174 0.036
multicellular organismal homeostasis GO:0048871 164 0.036
cyclic nucleotide metabolic process GO:0009187 59 0.036
respiratory system development GO:0060541 190 0.036
regulation of cell growth GO:0001558 91 0.036
response to metal ion GO:0010038 47 0.036
Worm
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.036
regulation of mitosis GO:0007088 29 0.036
sensory organ morphogenesis GO:0090596 242 0.035
gliogenesis GO:0042063 141 0.035
regulation of engulfment of apoptotic cell GO:1901074 2 0.035
neuromuscular process GO:0050905 99 0.035
ear development GO:0043583 200 0.035
female gamete generation GO:0007292 74 0.035
Fly
endocytosis GO:0006897 168 0.035
pallium development GO:0021543 120 0.035
lymphocyte proliferation GO:0046651 164 0.035
positive regulation of intracellular transport GO:0032388 70 0.035
negative regulation of molecular function GO:0044092 258 0.035
divalent inorganic cation transport GO:0072511 178 0.035
chemotaxis GO:0006935 247 0.035
Worm
mechanoreceptor differentiation GO:0042490 67 0.035
transition metal ion transport GO:0000041 38 0.034
Mouse
organic anion transport GO:0015711 137 0.034
endocrine system development GO:0035270 98 0.034
positive regulation of nucleoside metabolic process GO:0045979 91 0.034
gonad development GO:0008406 141 0.034
positive regulation of lamellipodium assembly GO:0010592 2 0.033
positive regulation of rho gtpase activity GO:0032321 41 0.033
maintenance of location GO:0051235 89 0.033
positive regulation of rap gtpase activity GO:0032854 3 0.033
hyperosmotic response GO:0006972 4 0.033
transmission of nerve impulse GO:0019226 76 0.033
negative regulation of protein modification process GO:0031400 163 0.033
peptidyl tyrosine phosphorylation GO:0018108 143 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.033
protein maturation GO:0051604 176 0.033
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.033
nuclear division GO:0000280 158 0.033
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.033
activation of immune response GO:0002253 138 0.033
dna modification GO:0006304 50 0.032
Mouse
response to insulin GO:0032868 100 0.032
regulation of organ morphogenesis GO:2000027 144 0.032
developmental cell growth GO:0048588 84 0.032
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.032
regulation of protein transport GO:0051223 163 0.032
regulation of osteoclast differentiation GO:0045670 36 0.032
central nervous system neuron differentiation GO:0021953 162 0.032
anoikis GO:0043276 6 0.032
regulation of cell activation GO:0050865 289 0.032
granulocyte migration GO:0097530 43 0.032
neuron projection guidance GO:0097485 141 0.031
exocytosis GO:0006887 121 0.031
spermatogenesis GO:0007283 284 0.031
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.031
dna methylation GO:0006306 43 0.031
Mouse
regulation of mitotic cell cycle phase transition GO:1901990 73 0.031
golgi localization GO:0051645 4 0.031
modification dependent macromolecule catabolic process GO:0043632 133 0.031
hair cycle GO:0042633 90 0.031
male gamete generation GO:0048232 285 0.031
proteasomal protein catabolic process GO:0010498 98 0.031
response to acid chemical GO:0001101 111 0.031
respiratory tube development GO:0030323 167 0.031
negative regulation of cell cycle process GO:0010948 69 0.030
negative regulation of protein processing GO:0010955 79 0.030
regulation of protein binding GO:0043393 60 0.030
positive regulation of lipid metabolic process GO:0045834 40 0.030
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.030
negative regulation of apoptotic signaling pathway GO:2001234 104 0.030
regulation of membrane potential GO:0042391 192 0.030
negative regulation of blood pressure GO:0045776 22 0.030
sulfur compound biosynthetic process GO:0044272 37 0.029
ribonucleotide biosynthetic process GO:0009260 59 0.029
response to peptide GO:1901652 136 0.029
positive regulation of nucleotide metabolic process GO:0045981 114 0.029
hypomethylation of cpg island GO:0044029 1 0.029
Mouse
skeletal muscle organ development GO:0060538 163 0.029
epidermis development GO:0008544 187 0.029
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.029
cell junction assembly GO:0034329 52 0.029
regulation of neuron projection development GO:0010975 169 0.029
Fly
adherens junction organization GO:0034332 28 0.029
lung development GO:0030324 164 0.029
syncytium formation GO:0006949 43 0.029
defense response to other organism GO:0098542 197 0.029
zinc ion transmembrane transport GO:0071577 10 0.029
Mouse
establishment of tissue polarity GO:0007164 28 0.028
generation of precursor metabolites and energy GO:0006091 103 0.028
negative regulation of cell size GO:0045792 3 0.028
t cell differentiation GO:0030217 174 0.028
regulation of vacuole organization GO:0044088 4 0.028
regulation of binding GO:0051098 111 0.028
multicellular organism growth GO:0035264 161 0.028
Mouse Fly
regulation of cell cycle GO:0051726 281 0.028
Fly
amide transport GO:0042886 138 0.028
regulation of hormone levels GO:0010817 211 0.028
sensory perception of mechanical stimulus GO:0050954 107 0.028
skeletal system morphogenesis GO:0048705 203 0.028
tumor necrosis factor production GO:0032640 50 0.028
positive regulation of hydrolase activity GO:0051345 148 0.028
axon guidance GO:0007411 141 0.027
cell cell junction organization GO:0045216 72 0.027
establishment of protein localization to membrane GO:0090150 54 0.027
inner ear morphogenesis GO:0042472 101 0.027
neuronal action potential GO:0019228 54 0.027
response to testosterone GO:0033574 3 0.027
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.027
peptide transport GO:0015833 133 0.027
regulation of defense response GO:0031347 233 0.027
stem cell differentiation GO:0048863 268 0.027
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.027
cytokine mediated signaling pathway GO:0019221 115 0.027
positive regulation of chemotaxis GO:0050921 38 0.027
neural precursor cell proliferation GO:0061351 121 0.027
negative regulation of lymphocyte activation GO:0051250 91 0.027
pigment metabolic process GO:0042440 32 0.027
morphogenesis of a polarized epithelium GO:0001738 37 0.027
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.027
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
single organism nuclear import GO:1902593 95 0.026

Pik3cb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
thoracic cancer DOID:5093 0 0.142
cancer DOID:162 0 0.142
disease of cellular proliferation DOID:14566 0 0.142
organ system cancer DOID:0050686 0 0.142
large intestine cancer DOID:5672 0 0.049
colon cancer DOID:219 0 0.049
gastrointestinal system cancer DOID:3119 0 0.049
intestinal cancer DOID:10155 0 0.049
colorectal cancer DOID:9256 0 0.049
breast cancer DOID:1612 0 0.040
disease of anatomical entity DOID:7 0 0.036
integumentary system disease DOID:16 0 0.036
immune system disease DOID:2914 0 0.031
skin disease DOID:37 0 0.028