Mus musculus

0 known processes

Mc2r

melanocortin 2 receptor

(Aliases: ACTHR)

Mc2r biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
c21 steroid hormone biosynthetic process GO:0006700 3 0.949
response to peptide hormone GO:0043434 127 0.607
Mouse
progesterone biosynthetic process GO:0006701 1 0.502
g protein coupled receptor signaling pathway GO:0007186 243 0.477
Zebrafish Mouse
progesterone metabolic process GO:0042448 4 0.410
cellular ketone metabolic process GO:0042180 84 0.346
negative regulation of immune system process GO:0002683 209 0.323
fat cell differentiation GO:0045444 160 0.279
steroid metabolic process GO:0008202 119 0.277
hormone biosynthetic process GO:0042446 16 0.264
regulation of blood pressure GO:0008217 93 0.262
myeloid cell differentiation GO:0030099 233 0.237
glucocorticoid metabolic process GO:0008211 9 0.229
regulation of secretion GO:0051046 274 0.227
divalent metal ion transport GO:0070838 172 0.197
myeloid leukocyte differentiation GO:0002573 119 0.190
cytokine production GO:0001816 319 0.188
response to peptide GO:1901652 136 0.183
Mouse
glucocorticoid biosynthetic process GO:0006704 5 0.181
cellular response to peptide GO:1901653 92 0.173
blood circulation GO:0008015 195 0.168
response to insulin GO:0032868 100 0.163
Mouse
response to organic cyclic compound GO:0014070 198 0.160
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.157
cation transport GO:0006812 399 0.156
divalent inorganic cation transport GO:0072511 178 0.144
forebrain development GO:0030900 302 0.143
blood vessel morphogenesis GO:0048514 285 0.133
regulation of metal ion transport GO:0010959 106 0.130
development of primary sexual characteristics GO:0045137 143 0.128
calcium ion transport GO:0006816 159 0.123
circulatory system process GO:0003013 197 0.122
regulation of neuron death GO:1901214 134 0.122
regulation of angiogenesis GO:0045765 81 0.117
maintenance of location GO:0051235 89 0.117
cytoplasmic transport GO:0016482 234 0.115
immune response activating signal transduction GO:0002757 116 0.112
positive regulation of intracellular transport GO:0032388 70 0.112
fat soluble vitamin biosynthetic process GO:0042362 4 0.110
glycoprotein biosynthetic process GO:0009101 89 0.104
endocrine process GO:0050886 39 0.103
carbohydrate derivative biosynthetic process GO:1901137 183 0.103
Human Zebrafish
fat soluble vitamin catabolic process GO:0042363 1 0.103
connective tissue development GO:0061448 179 0.103
response to organonitrogen compound GO:0010243 246 0.103
Mouse
leukocyte differentiation GO:0002521 342 0.101
regulation of hormone levels GO:0010817 211 0.101
Mouse
response to molecule of bacterial origin GO:0002237 143 0.100
cellular lipid metabolic process GO:0044255 323 0.095
carbohydrate metabolic process GO:0005975 230 0.095
hormone metabolic process GO:0042445 86 0.094
cytokine metabolic process GO:0042107 71 0.092
lipid biosynthetic process GO:0008610 179 0.091
dibenzo p dioxin metabolic process GO:0018894 1 0.091
cellular divalent inorganic cation homeostasis GO:0072503 127 0.091
regulation of epithelial cell proliferation GO:0050678 141 0.089
oxidation reduction process GO:0055114 342 0.087
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.087
calcium ion transport into cytosol GO:0060402 48 0.086
angiogenesis GO:0001525 201 0.086
organic cyclic compound catabolic process GO:1901361 295 0.085
vitamin d3 metabolic process GO:0070640 3 0.084
regulation of membrane potential GO:0042391 192 0.084
regulation of secretion by cell GO:1903530 249 0.081
cytokine secretion GO:0050663 72 0.080
calcium ion homeostasis GO:0055074 127 0.080
digestive system development GO:0055123 200 0.079
corticosterone secretion GO:0035934 3 0.077
organelle localization GO:0051640 179 0.076
neuron projection guidance GO:0097485 141 0.076
response to corticosterone GO:0051412 1 0.075
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.075
cellular response to inorganic substance GO:0071241 37 0.074
negative regulation of cell proliferation GO:0008285 296 0.073
feeding behavior GO:0007631 62 0.072
Mouse
steroid biosynthetic process GO:0006694 47 0.072
regulation of system process GO:0044057 200 0.072
cellular carbohydrate metabolic process GO:0044262 119 0.070
gland development GO:0048732 330 0.070
Zebrafish
cellular response to organonitrogen compound GO:0071417 145 0.070
cellular alcohol biosynthetic process GO:0044108 3 0.069
regulation of lipid transport GO:0032368 36 0.067
cellular response to cadmium ion GO:0071276 3 0.067
cellular homeostasis GO:0019725 240 0.067
cellular response to peptide hormone stimulus GO:0071375 92 0.067
divalent inorganic cation homeostasis GO:0072507 138 0.067
anatomical structure homeostasis GO:0060249 145 0.065
Mouse
secondary alcohol metabolic process GO:1902652 3 0.065
gonad development GO:0008406 141 0.064
positive regulation of behavior GO:0048520 40 0.063
regulation of leukocyte mediated immunity GO:0002703 104 0.063
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.062
ion transmembrane transport GO:0034220 361 0.062
positive regulation of cell migration GO:0030335 109 0.062
regulation of cell activation GO:0050865 289 0.062
regulation of corticosterone secretion GO:2000852 2 0.061
positive regulation of nervous system development GO:0051962 221 0.061
regulation of feeding behavior GO:0060259 3 0.061
sequestering of calcium ion GO:0051208 18 0.060
cellular metal ion homeostasis GO:0006875 151 0.060
neuronal action potential GO:0019228 54 0.060
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.060
cytosolic calcium ion homeostasis GO:0051480 70 0.060
response to oxidative stress GO:0006979 123 0.060
transmembrane transport GO:0055085 412 0.058
mineralocorticoid biosynthetic process GO:0006705 1 0.058
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.057
intracellular protein transport GO:0006886 204 0.057
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.057
chemotaxis GO:0006935 247 0.057
female sex differentiation GO:0046660 84 0.057
positive regulation of cell development GO:0010720 237 0.057
alanine transport GO:0032328 4 0.057
vascular process in circulatory system GO:0003018 62 0.057
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.056
sequestering of metal ion GO:0051238 19 0.056
response to lipopolysaccharide GO:0032496 128 0.056
homeostasis of number of cells GO:0048872 210 0.056
polysaccharide metabolic process GO:0005976 39 0.055
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.055
multicellular organism growth GO:0035264 161 0.055
locomotory behavior GO:0007626 195 0.054
cellular response to metal ion GO:0071248 31 0.054
calcitriol biosynthetic process from calciol GO:0036378 3 0.054
regulation of vasculature development GO:1901342 88 0.053
glucan metabolic process GO:0044042 32 0.052
carbohydrate homeostasis GO:0033500 128 0.052
organic hydroxy compound transport GO:0015850 93 0.052
mature dendritic cell differentiation GO:0097029 3 0.052
apoptotic signaling pathway GO:0097190 306 0.051
regulation of cellular amino acid metabolic process GO:0006521 5 0.051
regulation of fat cell differentiation GO:0045598 81 0.051
negative regulation of myeloid cell differentiation GO:0045638 38 0.051
response to metal ion GO:0010038 47 0.050
hormone secretion GO:0046879 128 0.049
Mouse
response to radiation GO:0009314 165 0.049
regulation of organelle organization GO:0033043 289 0.048
glucose homeostasis GO:0042593 128 0.048
regulation of cytokine production GO:0001817 266 0.048
defense response to other organism GO:0098542 197 0.048
negative regulation of molecular function GO:0044092 258 0.047
dna metabolic process GO:0006259 303 0.047
endocrine system development GO:0035270 98 0.047
Zebrafish
regulation of monocyte extravasation GO:2000437 2 0.047
second messenger mediated signaling GO:0019932 73 0.046
epithelial tube morphogenesis GO:0060562 303 0.046
negative regulation of cellular protein metabolic process GO:0032269 247 0.046
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.046
Human Zebrafish
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.045
negative regulation of vasculature development GO:1901343 26 0.045
multi multicellular organism process GO:0044706 109 0.045
phenol containing compound biosynthetic process GO:0046189 21 0.045
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.045
aldosterone metabolic process GO:0032341 2 0.045
negative regulation of protein metabolic process GO:0051248 282 0.044
regulation of ion homeostasis GO:2000021 64 0.044
ameboidal type cell migration GO:0001667 128 0.044
intracellular receptor signaling pathway GO:0030522 74 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
carbohydrate biosynthetic process GO:0016051 74 0.043
positive regulation of angiogenesis GO:0045766 46 0.043
regulation of cellular amine metabolic process GO:0033238 20 0.043
chromatin modification GO:0016568 187 0.043
regulation of transferase activity GO:0051338 263 0.043
regulation of transmembrane transport GO:0034762 128 0.042
cell activation involved in immune response GO:0002263 126 0.042
intracellular distribution of mitochondria GO:0048312 1 0.042
glial cell differentiation GO:0010001 131 0.042
membrane organization GO:0061024 245 0.042
immune response regulating signaling pathway GO:0002764 125 0.042
negative regulation of neuron death GO:1901215 98 0.042
myeloid cell homeostasis GO:0002262 114 0.041
leukocyte mediated immunity GO:0002443 174 0.041
cellular chemical homeostasis GO:0055082 215 0.041
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.040
Human Zebrafish
regulation of hydrolase activity GO:0051336 246 0.040
response to mineralocorticoid GO:0051385 1 0.040
purine nucleotide metabolic process GO:0006163 302 0.040
Human Zebrafish
nitrogen compound transport GO:0071705 271 0.040
Mouse
positive regulation of immune effector process GO:0002699 107 0.040
positive regulation of immunological synapse formation GO:2000522 1 0.040
cellular calcium ion homeostasis GO:0006874 119 0.039
covalent chromatin modification GO:0016569 163 0.039
regulation of intracellular transport GO:0032386 159 0.039
regulation of inflammatory response GO:0050727 147 0.039
peptidyl amino acid modification GO:0018193 336 0.039
response to inactivity GO:0014854 4 0.039
regulation of establishment of protein localization GO:0070201 181 0.039
morphogenesis of embryonic epithelium GO:0016331 159 0.039
amino acid transmembrane transport GO:0003333 37 0.038
response to alkaloid GO:0043279 34 0.038
striated muscle tissue development GO:0014706 293 0.038
negative regulation of cell activation GO:0050866 111 0.038
positive regulation of camp metabolic process GO:0030816 19 0.038
Human Zebrafish
vitamin d biosynthetic process GO:0042368 3 0.038
epithelial cell proliferation GO:0050673 174 0.038
purine ribonucleotide metabolic process GO:0009150 290 0.037
Human Zebrafish
regulation of blood volume by renal aldosterone GO:0002017 1 0.037
skeletal system development GO:0001501 356 0.037
neural tube formation GO:0001841 108 0.037
regulation of apoptotic signaling pathway GO:2001233 197 0.037
cellular polysaccharide metabolic process GO:0044264 38 0.037
regulation of response to wounding GO:1903034 189 0.037
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
positive regulation of protein transport GO:0051222 93 0.037
regulation of defense response GO:0031347 233 0.037
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 13 0.036
phenol containing compound metabolic process GO:0018958 60 0.036
Mouse
synaptic transmission GO:0007268 329 0.036
Zebrafish
somitogenesis GO:0001756 69 0.036
wnt signaling pathway GO:0016055 188 0.036
cellular amine metabolic process GO:0044106 44 0.036
aldosterone biosynthetic process GO:0032342 1 0.035
positive regulation of cytokine production GO:0001819 174 0.035
regulation of blood vessel size GO:0050880 56 0.035
negative regulation of lymphocyte activation GO:0051250 91 0.035
response to alcohol GO:0097305 48 0.035
multicellular organismal homeostasis GO:0048871 164 0.035
Mouse
regulation of tube size GO:0035150 57 0.035
regulation of angiotensin levels in blood GO:0002002 4 0.034
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.034
Human Zebrafish
spermatogenesis GO:0007283 284 0.034
pallium development GO:0021543 120 0.034
positive regulation of keratinocyte proliferation GO:0010838 4 0.034
regulation of blood circulation GO:1903522 93 0.034
cell adhesion GO:0007155 329 0.034
cellular response to antibiotic GO:0071236 4 0.033
digestive tract development GO:0048565 190 0.033
nucleotide metabolic process GO:0009117 332 0.033
Human Zebrafish
hematopoietic stem cell migration GO:0035701 1 0.033
response to follicle stimulating hormone GO:0032354 1 0.033
positive regulation of steroid hormone secretion GO:2000833 2 0.032
regulation of anatomical structure size GO:0090066 178 0.032
cellular response to lipid GO:0071396 145 0.032
eosinophil degranulation GO:0043308 1 0.032
positive regulation of t cell costimulation GO:2000525 2 0.032
positive regulation of camp mediated signaling GO:0043950 3 0.032
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.032
protein secretion GO:0009306 111 0.032
regulation of chemotaxis GO:0050920 53 0.032
negative regulation of angiogenesis GO:0016525 25 0.032
response to inorganic substance GO:0010035 96 0.031
regulation of kinase activity GO:0043549 249 0.031
regulation of calcium ion transport GO:0051924 69 0.031
hematopoietic progenitor cell differentiation GO:0002244 143 0.031
cellular response to hormone stimulus GO:0032870 150 0.031
negative regulation of protein modification process GO:0031400 163 0.031
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.031
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.031
cellular ion homeostasis GO:0006873 165 0.031
energy reserve metabolic process GO:0006112 39 0.030
canonical wnt signaling pathway GO:0060070 130 0.030
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.030
naphthalene containing compound metabolic process GO:0090420 1 0.030
heterocycle catabolic process GO:0046700 280 0.030
endothelium development GO:0003158 45 0.030
regulation of monocyte chemotaxis GO:0090025 3 0.029
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.029
amine metabolic process GO:0009308 45 0.029
helper t cell chemotaxis GO:0035704 1 0.029
regulation of steroid biosynthetic process GO:0050810 26 0.029
nucleoside metabolic process GO:0009116 246 0.029
t cell extravasation GO:0072683 4 0.029
epithelial tube formation GO:0072175 130 0.029
regulation of estrogen secretion GO:2000861 1 0.029
regulation of myeloid cell differentiation GO:0045637 96 0.029
t helper 17 cell chemotaxis GO:0035705 1 0.029
anion transport GO:0006820 177 0.029
regulation of microvillus assembly GO:0032534 3 0.029
brown fat cell differentiation GO:0050873 36 0.029
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.029
organonitrogen compound catabolic process GO:1901565 264 0.029
positive regulation of monocyte chemotaxis GO:0090026 2 0.028
response to steroid hormone GO:0048545 56 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
motor neuron axon guidance GO:0008045 26 0.028
organophosphate biosynthetic process GO:0090407 122 0.028
Human Zebrafish
cellular response to gonadotropin stimulus GO:0071371 4 0.028
heart process GO:0003015 94 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.028
carbohydrate derivative catabolic process GO:1901136 231 0.028
eosinophil activation GO:0043307 1 0.027
glycosyl compound metabolic process GO:1901657 246 0.027
notch signaling pathway GO:0007219 71 0.027
multicellular organismal signaling GO:0035637 91 0.027
steroid hormone secretion GO:0035929 9 0.027
renal system process GO:0003014 48 0.027
negative regulation of phosphorus metabolic process GO:0010563 184 0.027
activation of immune response GO:0002253 138 0.027
regulation of auditory receptor cell differentiation GO:0045607 4 0.027
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.027
respiratory tube development GO:0030323 167 0.027
acetylcholine metabolic process GO:0008291 3 0.027
regulation of ion transport GO:0043269 215 0.027
negative regulation of secretion GO:0051048 61 0.026
action potential GO:0001508 78 0.026
renal system development GO:0072001 225 0.026
regulation of cellular ketone metabolic process GO:0010565 66 0.026
cartilage development GO:0051216 140 0.026
embryonic epithelial tube formation GO:0001838 130 0.026
cellular glucan metabolic process GO:0006073 32 0.026
detection of yeast GO:0001879 2 0.026
small gtpase mediated signal transduction GO:0007264 97 0.026
interleukin 12 secretion GO:0072610 3 0.026
hexose metabolic process GO:0019318 98 0.026
leukocyte activation involved in immune response GO:0002366 126 0.025
male gamete generation GO:0048232 285 0.025
cell maturation GO:0048469 127 0.025
cellular amino acid metabolic process GO:0006520 103 0.025
organic hydroxy compound biosynthetic process GO:1901617 77 0.025
Mouse
c21 steroid hormone metabolic process GO:0008207 7 0.025
purine nucleotide biosynthetic process GO:0006164 65 0.025
Human Zebrafish
microglial cell activation GO:0001774 3 0.025
regulation of endocrine process GO:0044060 13 0.025
lymphocyte differentiation GO:0030098 242 0.025
transmission of nerve impulse GO:0019226 76 0.025
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.025
male gonad development GO:0008584 88 0.024
regulation of hemostasis GO:1900046 28 0.024
energy derivation by oxidation of organic compounds GO:0015980 77 0.024
regulation of immunological synapse formation GO:2000520 2 0.024
glucose metabolic process GO:0006006 92 0.024
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 3 0.024
keratinocyte migration GO:0051546 3 0.024
negative regulation of growth GO:0045926 99 0.024
development of primary female sexual characteristics GO:0046545 73 0.024
regulation of vesicle mediated transport GO:0060627 139 0.024
immune effector process GO:0002252 321 0.024
hippocampus development GO:0021766 52 0.024
regulation of steroid hormone biosynthetic process GO:0090030 4 0.024
cellular response to insulin stimulus GO:0032869 78 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.023
bone morphogenesis GO:0060349 78 0.023
circadian rhythm GO:0007623 114 0.023
negative regulation of camp mediated signaling GO:0043951 3 0.023
g protein coupled receptor internalization GO:0002031 3 0.023
positive regulation of defense response GO:0031349 124 0.023
positive regulation of protein modification process GO:0031401 299 0.023
mineralocorticoid metabolic process GO:0008212 2 0.023
i kappab kinase nf kappab signaling GO:0007249 85 0.023
positive regulation of secretion GO:0051047 130 0.023
mucopolysaccharide metabolic process GO:1903510 25 0.023
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.023
respiratory system process GO:0003016 25 0.023
small molecule biosynthetic process GO:0044283 132 0.023
female gonad development GO:0008585 71 0.023
respiratory system development GO:0060541 190 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
Human Zebrafish
monocyte extravasation GO:0035696 2 0.023
activation of adenylate cyclase activity GO:0007190 4 0.022
branching morphogenesis of an epithelial tube GO:0048754 159 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.022
muscle hypertrophy GO:0014896 24 0.022
purine containing compound metabolic process GO:0072521 311 0.022
Human Zebrafish
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
positive regulation of leukocyte mediated immunity GO:0002705 70 0.022
regulation of steroid metabolic process GO:0019218 39 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
chromatin organization GO:0006325 206 0.022
aromatic compound catabolic process GO:0019439 286 0.021
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
glycogen metabolic process GO:0005977 32 0.021
generation of precursor metabolites and energy GO:0006091 103 0.021
response to decreased oxygen levels GO:0036293 59 0.021
purine containing compound catabolic process GO:0072523 213 0.021
epithelial cell migration GO:0010631 63 0.021
cyclic nucleotide biosynthetic process GO:0009190 44 0.021
Human Zebrafish
eosinophil mediated immunity GO:0002447 1 0.021
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.021
habituation GO:0046959 3 0.021
somite development GO:0061053 81 0.021
regulation of body fluid levels GO:0050878 162 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
endothelial cell differentiation GO:0045446 41 0.021
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.021
erythrocyte differentiation GO:0030218 88 0.020
regulation of ion transmembrane transport GO:0034765 119 0.020
carboxylic acid transport GO:0046942 100 0.020
negative regulation of cholesterol transport GO:0032375 4 0.020
positive regulation of neutrophil chemotaxis GO:0090023 12 0.020
positive regulation of response to wounding GO:1903036 66 0.020
positive regulation of monocyte extravasation GO:2000439 1 0.020
regulation of fat cell proliferation GO:0070344 4 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
organic hydroxy compound catabolic process GO:1901616 25 0.020
response to acid chemical GO:0001101 111 0.020
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.020
negative regulation of secretion by cell GO:1903531 54 0.020
negative regulation of synapse maturation GO:2000297 2 0.020
lipid localization GO:0010876 126 0.020
cell cell signaling involved in mammary gland development GO:0060764 2 0.020
cell division GO:0051301 120 0.020
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.020
alcohol metabolic process GO:0006066 116 0.020
vitamin catabolic process GO:0009111 1 0.020
tube formation GO:0035148 140 0.020
cytosolic calcium ion transport GO:0060401 48 0.020
regulation of organ morphogenesis GO:2000027 144 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
response to nutrient levels GO:0031667 109 0.020
catecholamine metabolic process GO:0006584 30 0.020
bone development GO:0060348 120 0.020
t cell differentiation in thymus GO:0033077 77 0.020
negative regulation of phosphorylation GO:0042326 166 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
positive regulation of chemotaxis GO:0050921 38 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
negative regulation of endothelial cell migration GO:0010596 4 0.019
cation homeostasis GO:0055080 212 0.019
negative regulation of homeostatic process GO:0032845 71 0.019
development of primary male sexual characteristics GO:0046546 88 0.019
monosaccharide transport GO:0015749 58 0.019
negative regulation of eosinophil degranulation GO:0043310 1 0.019
protein localization to organelle GO:0033365 185 0.019
coagulation GO:0050817 78 0.019
cell type specific apoptotic process GO:0097285 268 0.019
ketone biosynthetic process GO:0042181 8 0.019
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.019
negative regulation of transferase activity GO:0051348 85 0.019
regulation of glucose metabolic process GO:0010906 60 0.019
lymphocyte activation involved in immune response GO:0002285 93 0.019
epithelial cell development GO:0002064 159 0.019
immune complex clearance by monocytes and macrophages GO:0002436 2 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
stem cell proliferation GO:0072089 117 0.018
l amino acid transport GO:0015807 32 0.018
glycoprotein metabolic process GO:0009100 116 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
Human Zebrafish
regulation of transporter activity GO:0032409 57 0.018
skin development GO:0043588 220 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
regulation of muscle tissue development GO:1901861 97 0.018
regulation of wnt signaling pathway GO:0030111 123 0.018
immune complex clearance GO:0002434 2 0.018
cofactor metabolic process GO:0051186 80 0.018
mitochondrion organization GO:0007005 134 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
microglial cell activation involved in immune response GO:0002282 1 0.018
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.018
striated muscle hypertrophy GO:0014897 24 0.018
stem cell differentiation GO:0048863 268 0.018
ureteric bud development GO:0001657 94 0.018
eosinophil activation involved in immune response GO:0002278 1 0.018
regulation of systemic arterial blood pressure GO:0003073 61 0.018
negative regulation of ossification GO:0030279 49 0.018
muscle tissue development GO:0060537 308 0.018
morphogenesis of a branching epithelium GO:0061138 193 0.018
wound healing GO:0042060 157 0.018
sensory perception GO:0007600 245 0.018
Mouse
tube closure GO:0060606 91 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
Human Zebrafish
aortic valve morphogenesis GO:0003180 4 0.018
cellular response to organic cyclic compound GO:0071407 87 0.018
protein targeting GO:0006605 143 0.018
blood coagulation GO:0007596 76 0.018
negative regulation of epithelial cell proliferation GO:0050680 64 0.017
regulation of cell motility GO:2000145 236 0.017
regulation of lipid metabolic process GO:0019216 118 0.017
tissue remodeling GO:0048771 102 0.017
Mouse
regulation of mapk cascade GO:0043408 248 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
neural crest cell differentiation GO:0014033 54 0.017
response to extracellular stimulus GO:0009991 127 0.017
positive regulation of secretion by cell GO:1903532 114 0.017
positive regulation of t cell extravasation GO:2000409 2 0.017
nucleotide catabolic process GO:0009166 217 0.017
dentate gyrus development GO:0021542 14 0.017
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.017
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.017
regulation of glucocorticoid secretion GO:2000849 5 0.017
nucleoside phosphate biosynthetic process GO:1901293 79 0.017
Human Zebrafish
regulation of carbohydrate metabolic process GO:0006109 75 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
response to purine containing compound GO:0014074 28 0.017
sclerotome development GO:0061056 4 0.017
adaptive immune response GO:0002250 155 0.017
positive regulation of glycolytic process GO:0045821 4 0.017
limbic system development GO:0021761 72 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.016
Mouse
regulation of t cell mediated immunity GO:0002709 34 0.016
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.016
nuclear transport GO:0051169 139 0.016
organic anion transport GO:0015711 137 0.016
endocrine hormone secretion GO:0060986 15 0.016
ribose phosphate biosynthetic process GO:0046390 59 0.016
Human Zebrafish
regulation of hormone secretion GO:0046883 88 0.016
negative regulation of cell migration GO:0030336 59 0.016
gastrin induced gastric acid secretion GO:0001698 1 0.016
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.016
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.016

Mc2r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.067