Mus musculus

38 known processes

Rad51

RAD51 homolog (S. cerevisiae)

(Aliases: AV304093,Reca,Rad51a)

Rad51 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair GO:0006302 48 0.844
dna repair GO:0006281 107 0.797
recombinational repair GO:0000725 21 0.668
dna metabolic process GO:0006259 303 0.658
cellular response to dna damage stimulus GO:0006974 207 0.532
regulation of cell cycle process GO:0010564 160 0.496
meiotic cell cycle GO:0051321 122 0.493
male meiosis i GO:0007141 16 0.469
mitotic cell cycle GO:0000278 195 0.446
organelle fission GO:0048285 170 0.369
dna endoreduplication GO:0042023 4 0.366
sister chromatid segregation GO:0000819 20 0.351
deoxyribonucleotide biosynthetic process GO:0009263 6 0.328
positive regulation of histone h3 k4 methylation GO:0051571 5 0.328
double strand break repair via homologous recombination GO:0000724 21 0.285
meiosis i GO:0007127 60 0.279
Yeast
covalent chromatin modification GO:0016569 163 0.264
dna replication GO:0006260 52 0.242
Human
regulation of cell division GO:0051302 76 0.222
chromosome segregation GO:0007059 48 0.218
Worm
nucleobase containing small molecule metabolic process GO:0055086 352 0.199
Human Yeast Worm
intrinsic apoptotic signaling pathway GO:0097193 132 0.193
Worm
meiotic cell cycle process GO:1903046 77 0.192
Yeast Worm
inner cell mass cell proliferation GO:0001833 15 0.186
nuclear division GO:0000280 158 0.181
regulation of cell cycle GO:0051726 281 0.180
dna dependent dna replication GO:0006261 24 0.174
Human
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.172
histone acetylation GO:0016573 41 0.167
translesion synthesis GO:0019985 1 0.162
dna recombination GO:0006310 92 0.161
chromosome organization involved in meiosis GO:0070192 39 0.156
Worm
meiotic nuclear division GO:0007126 115 0.154
purine ribonucleotide metabolic process GO:0009150 290 0.151
Human Yeast Worm
cell cycle checkpoint GO:0000075 47 0.132
ubiquitin dependent protein catabolic process GO:0006511 129 0.129
cellular protein catabolic process GO:0044257 155 0.116
nucleoside phosphate metabolic process GO:0006753 338 0.113
Human Yeast Worm
histone modification GO:0016570 159 0.112
chromatin organization GO:0006325 206 0.105
purine nucleotide metabolic process GO:0006163 302 0.104
Human Yeast Worm
male meiosis GO:0007140 37 0.102
organic cyclic compound catabolic process GO:1901361 295 0.102
Human Yeast Worm
ribonucleotide metabolic process GO:0009259 291 0.102
Human Yeast Worm
response to light stimulus GO:0009416 135 0.100
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.098
microtubule cytoskeleton organization GO:0000226 157 0.096
regulation of mitotic sister chromatid segregation GO:0033047 12 0.095
development of primary sexual characteristics GO:0045137 143 0.092
protein catabolic process GO:0030163 221 0.091
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.091
Worm
purine nucleoside triphosphate metabolic process GO:0009144 226 0.090
Human Yeast Worm
blastocyst growth GO:0001832 23 0.089
microtubule based process GO:0007017 236 0.089
response to ionizing radiation GO:0010212 42 0.088
Human
nucleoside phosphate catabolic process GO:1901292 222 0.087
Human Yeast Worm
nucleoside triphosphate metabolic process GO:0009141 230 0.087
Human Yeast Worm
synapsis GO:0007129 34 0.083
apoptotic signaling pathway GO:0097190 306 0.082
Worm
regulation of cellular protein catabolic process GO:1903362 61 0.081
female meiosis chromosome segregation GO:0016321 1 0.080
response to radiation GO:0009314 165 0.079
Human
mitotic sister chromatid cohesion GO:0007064 1 0.079
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.078
regulation of chromosome organization GO:0033044 83 0.077
mitotic sister chromatid separation GO:0051306 9 0.076
cellular ketone metabolic process GO:0042180 84 0.074
dna replication independent nucleosome assembly GO:0006336 1 0.073
peptidyl amino acid modification GO:0018193 336 0.072
protein heterotetramerization GO:0051290 4 0.071
regulation of cell cycle g2 m phase transition GO:1902749 10 0.071
mitotic cell cycle process GO:1903047 159 0.070
mitotic sister chromatid segregation GO:0000070 14 0.070
regulation of histone modification GO:0031056 56 0.070
cellular amino acid metabolic process GO:0006520 103 0.069
cellular macromolecule catabolic process GO:0044265 206 0.069
gonad development GO:0008406 141 0.069
purine nucleoside catabolic process GO:0006152 205 0.068
Human Yeast Worm
cellular response to abiotic stimulus GO:0071214 56 0.067
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.066
Human Yeast Worm
spermatogenesis GO:0007283 284 0.065
nucleotide metabolic process GO:0009117 332 0.064
Human Yeast Worm
regulation of cellular amine metabolic process GO:0033238 20 0.064
regulation of organelle organization GO:0033043 289 0.063
chromatin modification GO:0016568 187 0.062
nucleoside catabolic process GO:0009164 206 0.061
Human Yeast Worm
purine containing compound metabolic process GO:0072521 311 0.060
Human Yeast Worm
purine containing compound catabolic process GO:0072523 213 0.060
Human Yeast Worm
regulation of lipid metabolic process GO:0019216 118 0.060
peptidyl lysine modification GO:0018205 77 0.059
oocyte maturation GO:0001556 18 0.058
amine metabolic process GO:0009308 45 0.057
negative regulation of cell cycle phase transition GO:1901988 48 0.057
nuclear dna replication GO:0033260 3 0.056
regulation of cellular ketone metabolic process GO:0010565 66 0.056
ribonucleoside catabolic process GO:0042454 206 0.055
Human Yeast Worm
protein ubiquitination GO:0016567 171 0.055
nucleoside metabolic process GO:0009116 246 0.053
Human Yeast Worm
carbohydrate derivative catabolic process GO:1901136 231 0.053
Human Yeast Worm
cytokinesis GO:0000910 17 0.053
male gamete generation GO:0048232 285 0.051
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.051
internal protein amino acid acetylation GO:0006475 42 0.050
response to inorganic substance GO:0010035 96 0.048
Zebrafish
regulation of cellular response to stress GO:0080135 159 0.048
Human Fly
purine ribonucleoside catabolic process GO:0046130 205 0.047
Human Yeast Worm
positive regulation of cellular catabolic process GO:0031331 148 0.047
positive regulation of protein modification process GO:0031401 299 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
endocytosis GO:0006897 168 0.044
protein modification by small protein conjugation or removal GO:0070647 207 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
membrane organization GO:0061024 245 0.042
macromolecule catabolic process GO:0009057 281 0.042
protein acylation GO:0043543 64 0.041
cellular lipid metabolic process GO:0044255 323 0.041
internal peptidyl lysine acetylation GO:0018393 42 0.041
lipid biosynthetic process GO:0008610 179 0.040
peptidyl lysine acetylation GO:0018394 45 0.040
histone h4 k16 acetylation GO:0043984 3 0.040
response to organic cyclic compound GO:0014070 198 0.039
Human Fly
ribonucleoside triphosphate metabolic process GO:0009199 220 0.039
Human Yeast Worm
blastocyst development GO:0001824 80 0.038
purine nucleoside triphosphate catabolic process GO:0009146 203 0.038
Human Yeast Worm
regulation of sister chromatid cohesion GO:0007063 5 0.038
negative regulation of histone h3 k9 methylation GO:0051573 4 0.037
ribose phosphate metabolic process GO:0019693 291 0.037
Human Yeast Worm
mitotic chromosome condensation GO:0007076 1 0.037
cell division GO:0051301 120 0.036
glycosyl compound catabolic process GO:1901658 206 0.036
Human Yeast Worm
negative regulation of cell cycle GO:0045786 123 0.036
organophosphate catabolic process GO:0046434 232 0.035
Human Yeast Worm
positive regulation of cell cycle GO:0045787 92 0.035
replication fork protection GO:0048478 1 0.035
organonitrogen compound catabolic process GO:1901565 264 0.035
Human Yeast Worm
purine ribonucleoside metabolic process GO:0046128 241 0.035
Human Yeast Worm
cellular response to ionizing radiation GO:0071479 11 0.034
Human
cellular response to radiation GO:0071478 28 0.033
Human
purine nucleoside metabolic process GO:0042278 241 0.033
Human Yeast Worm
organophosphate biosynthetic process GO:0090407 122 0.032
nucleotide biosynthetic process GO:0009165 78 0.032
maintenance of location GO:0051235 89 0.032
response to uv GO:0009411 44 0.032
regulation of dna dependent dna replication GO:0090329 8 0.031
genitalia development GO:0048806 37 0.030
cellular response to organonitrogen compound GO:0071417 145 0.030
Human
dna packaging GO:0006323 30 0.030
Worm
folic acid containing compound metabolic process GO:0006760 3 0.029
regulation of cytokinesis GO:0032465 5 0.029
negative regulation of proteolysis GO:0045861 74 0.029
ribonucleotide catabolic process GO:0009261 208 0.029
Human Yeast Worm
cellular amine metabolic process GO:0044106 44 0.028
mitotic nuclear division GO:0007067 48 0.028
striated muscle myosin thick filament assembly GO:0071688 1 0.028
heterocycle catabolic process GO:0046700 280 0.028
Human Yeast Worm
negative regulation of phosphorus metabolic process GO:0010563 184 0.027
negative regulation of phosphate metabolic process GO:0045936 184 0.027
regulation of mitosis GO:0007088 29 0.026
response to organonitrogen compound GO:0010243 246 0.026
Human Fly
histone h4 acetylation GO:0043967 10 0.026
metaphase plate congression GO:0051310 2 0.026
aromatic compound catabolic process GO:0019439 286 0.025
Human Yeast Worm
asymmetric stem cell division GO:0098722 3 0.025
modification dependent protein catabolic process GO:0019941 133 0.025
muscle cell differentiation GO:0042692 261 0.025
synaptonemal complex assembly GO:0007130 13 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
negative regulation of cell cycle process GO:0010948 69 0.024
regulation of peptidyl lysine acetylation GO:2000756 22 0.024
fatty acid metabolic process GO:0006631 121 0.024
meiotic chromosome segregation GO:0045132 19 0.023
Worm
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.023
regulation of transcription by chromatin organization GO:0034401 0 0.023
peptidyl serine modification GO:0018209 83 0.023
protein autophosphorylation GO:0046777 61 0.022
positive regulation of histone h3 k9 methylation GO:0051574 4 0.022
methylation GO:0032259 134 0.022
double strand break repair via nonhomologous end joining GO:0006303 10 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
attachment of spindle microtubules to kinetochore GO:0008608 4 0.021
cofactor metabolic process GO:0051186 80 0.021
deoxyribonucleotide metabolic process GO:0009262 14 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
negative regulation of protein modification process GO:0031400 163 0.020
gtp metabolic process GO:0046039 144 0.020
positive regulation of mitotic metaphase anaphase transition GO:0045842 2 0.020
proteasomal protein catabolic process GO:0010498 98 0.020
ras protein signal transduction GO:0007265 77 0.020
response to oxidative stress GO:0006979 123 0.020
regulation of chromosome segregation GO:0051983 21 0.019
positive regulation of organelle organization GO:0010638 128 0.019
dna damage checkpoint GO:0000077 26 0.019
cell type specific apoptotic process GO:0097285 268 0.019
heterochromatin organization GO:0070828 4 0.019
regulation of hydrolase activity GO:0051336 246 0.019
myosin filament assembly GO:0031034 2 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
regulation of nucleotide catabolic process GO:0030811 122 0.018
organelle localization GO:0051640 179 0.018
histone threonine phosphorylation GO:0035405 1 0.018
regulation of mitotic cell cycle phase transition GO:1901990 73 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
Human Yeast Worm
peptidyl serine phosphorylation GO:0018105 74 0.018
protein dna complex subunit organization GO:0071824 28 0.018
non recombinational repair GO:0000726 10 0.018
negative regulation of nucleoside metabolic process GO:0045978 11 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
protein import into nucleus GO:0006606 95 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
positive regulation of gtp catabolic process GO:0033126 85 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
Human Yeast Worm
cell cycle g1 s phase transition GO:0044843 57 0.017
asymmetric neuroblast division GO:0055059 1 0.017
gland development GO:0048732 330 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
nucleoside phosphate biosynthetic process GO:1901293 79 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
dna integrity checkpoint GO:0031570 28 0.017
regulation of mitotic cell cycle GO:0007346 126 0.017
monocarboxylic acid metabolic process GO:0032787 191 0.016
circadian temperature homeostasis GO:0060086 2 0.016
muscle cell development GO:0055001 133 0.016
mapk cascade GO:0000165 281 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
actin cytoskeleton organization GO:0030036 220 0.015
regulation of mammary gland epithelial cell proliferation GO:0033599 12 0.015
endomembrane system organization GO:0010256 147 0.015
oxidation reduction process GO:0055114 342 0.015
b cell activation GO:0042113 161 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
Human Yeast Worm
nucleotide catabolic process GO:0009166 217 0.015
Human Yeast Worm
cell cycle comprising mitosis without cytokinesis GO:0033301 1 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
Human Yeast Worm
establishment of organelle localization GO:0051656 122 0.015
female sex differentiation GO:0046660 84 0.015
female gamete generation GO:0007292 74 0.015
Fly
response to fibroblast growth factor GO:0071774 47 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
Human Yeast Worm
negative regulation of protein metabolic process GO:0051248 282 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
regulation of centriole replication GO:0046599 1 0.014
negative regulation of fatty acid metabolic process GO:0045922 10 0.014
regulation of proteasomal protein catabolic process GO:0061136 46 0.014
centromere complex assembly GO:0034508 3 0.014
response to alkaloid GO:0043279 34 0.014
Human Fly
mitotic cytokinesis GO:0000281 4 0.014
protein polyubiquitination GO:0000209 33 0.014
receptor mediated endocytosis GO:0006898 51 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
Human Yeast Worm
response to metal ion GO:0010038 47 0.014
Zebrafish
positive regulation of protein ubiquitination GO:0031398 27 0.014
chromosome separation GO:0051304 14 0.014
regulation of cell projection organization GO:0031344 206 0.013
chromatin remodeling at centromere GO:0031055 2 0.013
cation transport GO:0006812 399 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.013
regulation of protein catabolic process GO:0042176 108 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
blood circulation GO:0008015 195 0.013
small molecule biosynthetic process GO:0044283 132 0.013
branching morphogenesis of an epithelial tube GO:0048754 159 0.013
protein localization to organelle GO:0033365 185 0.013
regulation of protein maturation GO:1903317 96 0.013
leukocyte proliferation GO:0070661 172 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
regulation of cell cycle phase transition GO:1901987 77 0.013
striated muscle cell development GO:0055002 125 0.013
cell cycle g2 m phase transition GO:0044839 20 0.013
angiogenesis GO:0001525 201 0.013
regulation of binding GO:0051098 111 0.013
germ cell development GO:0007281 185 0.013
Fly
positive regulation of apoptotic process GO:0043065 217 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
Human Yeast Worm
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
nucleoside monophosphate catabolic process GO:0009125 59 0.012
Human Yeast Worm
positive regulation of protein kinase activity GO:0045860 144 0.012
negative regulation of lipid metabolic process GO:0045833 30 0.012
negative regulation of molecular function GO:0044092 258 0.012
chromatin silencing GO:0006342 15 0.012
meiosis ii GO:0007135 7 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
glycerolipid metabolic process GO:0046486 122 0.012
positive regulation of cell death GO:0010942 224 0.012
response to purine containing compound GO:0014074 28 0.012
Fly
dna unwinding involved in dna replication GO:0006268 5 0.012
Human
lateral inhibition GO:0046331 1 0.012
positive regulation of chromatin modification GO:1903310 28 0.012
regulation of mapk cascade GO:0043408 248 0.012
sister chromatid cohesion GO:0007062 12 0.012
histone h3 acetylation GO:0043966 14 0.012
protein processing GO:0016485 163 0.012
cell fate commitment GO:0045165 210 0.012
Fly
regulation of double strand break repair via homologous recombination GO:0010569 2 0.012
Human Fly
cellular response to light stimulus GO:0071482 19 0.012
protein targeting GO:0006605 143 0.012
carbohydrate homeostasis GO:0033500 128 0.012
gene silencing GO:0016458 38 0.012
positive regulation of histone modification GO:0031058 28 0.012
positive regulation of chromosome segregation GO:0051984 4 0.012
cellular homeostasis GO:0019725 240 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
Human Yeast Worm
synaptonemal complex organization GO:0070193 15 0.011
neural precursor cell proliferation GO:0061351 121 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
regulation of histone acetylation GO:0035065 19 0.011
anatomical structure homeostasis GO:0060249 145 0.011
Yeast
guanosine containing compound catabolic process GO:1901069 144 0.011
regulation of protein kinase activity GO:0045859 232 0.011
regulation of chromatin silencing GO:0031935 2 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
positive regulation of nervous system development GO:0051962 221 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
Human Yeast Worm
regulation of nucleotide metabolic process GO:0006140 169 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
cell adhesion GO:0007155 329 0.011
positive regulation of gtpase activity GO:0043547 85 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
regulation of chromatin modification GO:1903308 57 0.011
homeostasis of number of cells GO:0048872 210 0.010
dna modification GO:0006304 50 0.010
single fertilization GO:0007338 82 0.010
positive regulation of cell development GO:0010720 237 0.010
macromolecule methylation GO:0043414 120 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
regulation of nucleoside metabolic process GO:0009118 130 0.010
regulation of gtp catabolic process GO:0033124 113 0.010
ossification GO:0001503 216 0.010
locomotory behavior GO:0007626 195 0.010
cytoplasmic transport GO:0016482 234 0.010
negative regulation of mitotic cell cycle GO:0045930 58 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
Human
atp catabolic process GO:0006200 55 0.010
Human Yeast Worm
response to reactive oxygen species GO:0000302 56 0.010
dna methylation GO:0006306 43 0.010
negative regulation of cell division GO:0051782 24 0.010
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.010
response to nutrient levels GO:0031667 109 0.010
dna alkylation GO:0006305 43 0.010

Rad51 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.193
Human
disease of cellular proliferation DOID:14566 0 0.193
Human
organ system cancer DOID:0050686 0 0.065
Human
congenital hypoplastic anemia DOID:1342 0 0.047
immune system disease DOID:2914 0 0.047
aplastic anemia DOID:12449 0 0.047
disease of anatomical entity DOID:7 0 0.047
fanconi s anemia DOID:13636 0 0.047
bone marrow disease DOID:4961 0 0.047
anemia DOID:2355 0 0.047
hematopoietic system disease DOID:74 0 0.047
gastrointestinal system cancer DOID:3119 0 0.039
intestinal cancer DOID:10155 0 0.039
thoracic cancer DOID:5093 0 0.033
Human
reproductive organ cancer DOID:193 0 0.022
urinary system cancer DOID:3996 0 0.014
large intestine cancer DOID:5672 0 0.014
disease of metabolism DOID:0014667 0 0.014
carbohydrate metabolic disorder DOID:2978 0 0.014
inherited metabolic disorder DOID:655 0 0.014
colon cancer DOID:219 0 0.013
colorectal cancer DOID:9256 0 0.013
endocrine gland cancer DOID:170 0 0.013
immune system cancer DOID:0060083 0 0.013
hematologic cancer DOID:2531 0 0.013
male reproductive organ cancer DOID:3856 0 0.011
physical disorder DOID:0080015 0 0.011