Mus musculus

0 known processes

Prl8a8

prolactin family 8, subfamily a, member 81

(Aliases: 1600032B14Rik,PLP-Cgamma,AV036230,Prlpc3)

Prl8a8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of microvillus organization GO:0032530 3 0.820
Mouse
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.627
Mouse
regulation of microvillus assembly GO:0032534 3 0.484
Mouse
positive regulation of transforming growth factor beta secretion GO:2001203 1 0.302
regulation of transforming growth factor beta secretion GO:2001201 1 0.267
negative regulation of endothelial cell migration GO:0010596 4 0.206
Mouse
transforming growth factor beta secretion GO:0038044 1 0.188
cytokine production GO:0001816 319 0.154
anion transport GO:0006820 177 0.154
ion transmembrane transport GO:0034220 361 0.150
striated muscle tissue development GO:0014706 293 0.143
Mouse
negative regulation of myoblast differentiation GO:0045662 18 0.141
Mouse
skeletal muscle fiber development GO:0048741 58 0.121
Mouse
muscle tissue development GO:0060537 308 0.114
Mouse
regulation of interleukin 10 secretion GO:2001179 4 0.101
regulation of cell projection organization GO:0031344 206 0.093
Mouse
regulation of skeletal muscle fiber development GO:0048742 36 0.083
Mouse
myoblast differentiation GO:0045445 52 0.078
Mouse
regulation of striated muscle cell differentiation GO:0051153 81 0.074
Mouse
regulation of hydrolase activity GO:0051336 246 0.069
muscle fiber development GO:0048747 76 0.067
Mouse
stem cell proliferation GO:0072089 117 0.066
Mouse
positive regulation of nervous system development GO:0051962 221 0.066
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.065
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.065
macromolecule catabolic process GO:0009057 281 0.064
regulation of cellular amino acid metabolic process GO:0006521 5 0.064
ameboidal type cell migration GO:0001667 128 0.063
Mouse
myotube cell development GO:0014904 60 0.063
Mouse
sensory perception GO:0007600 245 0.061
positive regulation of stem cell proliferation GO:2000648 59 0.061
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.060
Mouse
myotube differentiation GO:0014902 105 0.059
Mouse
regulation of myoblast differentiation GO:0045661 29 0.058
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.058
sprouting angiogenesis GO:0002040 26 0.056
Mouse
ear development GO:0043583 200 0.056
regulation of blood pressure GO:0008217 93 0.055
cellular ketone metabolic process GO:0042180 84 0.054
negative regulation of muscle cell differentiation GO:0051148 33 0.053
Mouse
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.053
cellular amine metabolic process GO:0044106 44 0.050
organic anion transport GO:0015711 137 0.050
skeletal muscle organ development GO:0060538 163 0.050
Mouse
regulation of myotube differentiation GO:0010830 62 0.049
Mouse
organic acid transport GO:0015849 101 0.047
regulation of neuroblast proliferation GO:1902692 27 0.047
Mouse
regulation of stem cell proliferation GO:0072091 78 0.046
Mouse
leukocyte mediated immunity GO:0002443 174 0.046
regulation of cell projection assembly GO:0060491 38 0.045
Mouse
cellular amino acid metabolic process GO:0006520 103 0.045
blood vessel morphogenesis GO:0048514 285 0.043
Mouse
regulation of blood vessel endothelial cell migration GO:0043535 12 0.043
Mouse
positive regulation of angiogenesis GO:0045766 46 0.042
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.042
negative regulation of protein metabolic process GO:0051248 282 0.042
muscle cell development GO:0055001 133 0.042
Mouse
transmembrane transport GO:0055085 412 0.042
positive regulation of cytokine production GO:0001819 174 0.040
regulation of angiogenesis GO:0045765 81 0.040
Mouse
regulation of muscle tissue development GO:1901861 97 0.039
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.039
sensory perception of mechanical stimulus GO:0050954 107 0.038
response to organic cyclic compound GO:0014070 198 0.038
carboxylic acid transport GO:0046942 100 0.038
striated muscle cell development GO:0055002 125 0.038
Mouse
regulation of cytokine production GO:0001817 266 0.037
cation transport GO:0006812 399 0.036
regulation of membrane potential GO:0042391 192 0.036
circulatory system process GO:0003013 197 0.035
positive regulation of cell migration GO:0030335 109 0.035
Mouse
lipid transport GO:0006869 98 0.034
amine metabolic process GO:0009308 45 0.034
nitrogen compound transport GO:0071705 271 0.033
regulation of vasculature development GO:1901342 88 0.033
Mouse
blood circulation GO:0008015 195 0.033
protein maturation GO:0051604 176 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.032
protein processing GO:0016485 163 0.032
positive regulation of cell motility GO:2000147 116 0.032
Mouse
immune effector process GO:0002252 321 0.031
organic hydroxy compound metabolic process GO:1901615 203 0.031
regulation of protein transport GO:0051223 163 0.031
locomotory behavior GO:0007626 195 0.031
inorganic ion transmembrane transport GO:0098660 234 0.031
protein ubiquitination GO:0016567 171 0.031
regulation of protein localization GO:0032880 231 0.030
axonogenesis GO:0007409 274 0.030
placenta development GO:0001890 140 0.030
detection of stimulus GO:0051606 84 0.030
synaptic transmission GO:0007268 329 0.030
regulation of cytokine secretion GO:0050707 61 0.030
negative regulation of vasculature development GO:1901343 26 0.030
Mouse
response to vitamin d GO:0033280 3 0.030
chemotaxis GO:0006935 247 0.029
positive regulation of cell development GO:0010720 237 0.029
Mouse
protein catabolic process GO:0030163 221 0.029
positive regulation of cell projection organization GO:0031346 95 0.029
Mouse
regulation of thyroid hormone generation GO:2000609 4 0.029
angiogenesis GO:0001525 201 0.028
Mouse
development of primary female sexual characteristics GO:0046545 73 0.027
negative regulation of angiogenesis GO:0016525 25 0.027
Mouse
interleukin 10 secretion GO:0072608 4 0.027
g protein coupled receptor signaling pathway GO:0007186 243 0.027
regulation of secretion GO:0051046 274 0.026
positive regulation of protein transport GO:0051222 93 0.026
positive regulation of neural precursor cell proliferation GO:2000179 42 0.026
Mouse
neural precursor cell proliferation GO:0061351 121 0.026
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.026
regulation of cell migration GO:0030334 219 0.026
Mouse
defense response to other organism GO:0098542 197 0.026
protein modification by small protein conjugation GO:0032446 187 0.025
telencephalon development GO:0021537 186 0.025
tissue remodeling GO:0048771 102 0.025
regulation of secretion by cell GO:1903530 249 0.024
cellular response to organic cyclic compound GO:0071407 87 0.024
response to nutrient levels GO:0031667 109 0.024
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.024
gland development GO:0048732 330 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.023
regulation of transmembrane transport GO:0034762 128 0.023
regulation of anatomical structure size GO:0090066 178 0.023
muscle cell differentiation GO:0042692 261 0.023
Mouse
regulation of peptidase activity GO:0052547 96 0.023
negative regulation of blood vessel morphogenesis GO:2000181 25 0.023
Mouse
developmental maturation GO:0021700 193 0.023
protein kinase b signaling GO:0043491 74 0.023
regulation of cell motility GO:2000145 236 0.023
Mouse
tissue migration GO:0090130 68 0.023
Mouse
regulation of systemic arterial blood pressure GO:0003073 61 0.023
protein secretion GO:0009306 111 0.023
oxidation reduction process GO:0055114 342 0.023
production of molecular mediator of immune response GO:0002440 103 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
regulation of protein processing GO:0070613 96 0.022
negative regulation of cell development GO:0010721 169 0.022
cation transmembrane transport GO:0098655 266 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
carbohydrate metabolic process GO:0005975 230 0.021
regulation of protein maturation GO:1903317 96 0.021
response to lipopolysaccharide GO:0032496 128 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
regulation of transferase activity GO:0051338 263 0.021
feeding behavior GO:0007631 62 0.021
cardiac muscle tissue development GO:0048738 130 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
negative regulation of protein processing GO:0010955 79 0.020
hormone metabolic process GO:0042445 86 0.020
regulation of protein secretion GO:0050708 82 0.019
cellular response to testosterone stimulus GO:0071394 1 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
negative regulation of hydrolase activity GO:0051346 71 0.019
positive regulation of nucleotide metabolic process GO:0045981 114 0.019
cation homeostasis GO:0055080 212 0.018
negative regulation of proteolysis GO:0045861 74 0.018
regulation of system process GO:0044057 200 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
fat cell differentiation GO:0045444 160 0.018
epithelium migration GO:0090132 63 0.018
Mouse
carnitine transport GO:0015879 3 0.018
response to peptide hormone GO:0043434 127 0.017
positive regulation of endothelial cell migration GO:0010595 12 0.017
Mouse
lymphocyte mediated immunity GO:0002449 139 0.017
purine containing compound metabolic process GO:0072521 311 0.017
hexose metabolic process GO:0019318 98 0.017
negative regulation of cell migration GO:0030336 59 0.017
Mouse
cellular response to peptide GO:1901653 92 0.017
second messenger mediated signaling GO:0019932 73 0.017
response to peptide GO:1901652 136 0.017
action potential GO:0001508 78 0.017
mechanoreceptor differentiation GO:0042490 67 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
cellular response to external stimulus GO:0071496 88 0.017
apoptotic signaling pathway GO:0097190 306 0.016
blood vessel endothelial cell migration GO:0043534 23 0.016
Mouse
amino acid betaine transport GO:0015838 3 0.016
glycerolipid metabolic process GO:0046486 122 0.016
neuroblast proliferation GO:0007405 49 0.016
Mouse
monosaccharide metabolic process GO:0005996 106 0.016
negative regulation of cell motility GO:2000146 61 0.016
Mouse
response to molecule of bacterial origin GO:0002237 143 0.016
heterocycle catabolic process GO:0046700 280 0.016
defense response to bacterium GO:0042742 119 0.016
extracellular structure organization GO:0043062 148 0.016
response to testosterone GO:0033574 3 0.016
epithelial cell migration GO:0010631 63 0.016
Mouse
inner ear morphogenesis GO:0042472 101 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
cell maturation GO:0048469 127 0.015
protein oligomerization GO:0051259 67 0.015
regulation of hormone levels GO:0010817 211 0.015
odontogenesis of dentin containing tooth GO:0042475 66 0.015
leukocyte differentiation GO:0002521 342 0.015
inner ear receptor cell differentiation GO:0060113 61 0.015
multicellular organismal signaling GO:0035637 91 0.015
nucleobase containing small molecule metabolic process GO:0055086 352 0.015
metal ion homeostasis GO:0055065 189 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
regulation of response to wounding GO:1903034 189 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
regulation of proteolysis GO:0030162 164 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
innate immune response GO:0045087 157 0.015
sensory organ morphogenesis GO:0090596 242 0.014
aromatic compound catabolic process GO:0019439 286 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
carnitine transmembrane transport GO:1902603 3 0.014
regulation of fat cell differentiation GO:0045598 81 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
maintenance of location GO:0051235 89 0.014
neuron migration GO:0001764 122 0.014
developmental cell growth GO:0048588 84 0.014
negative regulation of neuron death GO:1901215 98 0.014
amide transport GO:0042886 138 0.014
epithelial cell development GO:0002064 159 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
heart process GO:0003015 94 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
midgut development GO:0007494 4 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
interspecies interaction between organisms GO:0044419 83 0.014
peptidyl tyrosine modification GO:0018212 145 0.014
nucleotide metabolic process GO:0009117 332 0.013
cytokine secretion GO:0050663 72 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
regulation of defense response GO:0031347 233 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
cellular homeostasis GO:0019725 240 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
positive regulation of protein secretion GO:0050714 52 0.013
positive regulation of neuroblast proliferation GO:0002052 19 0.013
Mouse
regulation of tube size GO:0035150 57 0.013
regulation of cellular response to stress GO:0080135 159 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
palate development GO:0060021 76 0.013
pilomotor reflex GO:0097195 3 0.013
wound healing GO:0042060 157 0.013
multi multicellular organism process GO:0044706 109 0.013
Rat
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
synapse organization GO:0050808 125 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
metencephalon development GO:0022037 89 0.013
response to acid chemical GO:0001101 111 0.013
b cell mediated immunity GO:0019724 71 0.013
circadian rhythm GO:0007623 114 0.013
anion transmembrane transport GO:0098656 71 0.012
cellular chemical homeostasis GO:0055082 215 0.012
cellular response to lipid GO:0071396 145 0.012
female gonad development GO:0008585 71 0.012
peptidyl amino acid modification GO:0018193 336 0.012
negative regulation of molecular function GO:0044092 258 0.012
peptide metabolic process GO:0006518 46 0.012
muscle contraction GO:0006936 101 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
cell differentiation involved in embryonic placenta development GO:0060706 26 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
regulation of epithelial cell migration GO:0010632 35 0.012
Mouse
glucose metabolic process GO:0006006 92 0.012
response to growth factor GO:0070848 198 0.012
inflammatory response GO:0006954 244 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
skin development GO:0043588 220 0.012
neuron apoptotic process GO:0051402 142 0.012
ectoderm formation GO:0001705 3 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
ear morphogenesis GO:0042471 118 0.012
negative regulation of protein maturation GO:1903318 79 0.012
monocarboxylic acid transport GO:0015718 44 0.012
detection of external stimulus GO:0009581 61 0.012
regulation of protein kinase b signaling GO:0051896 56 0.012
cytokine biosynthetic process GO:0042089 68 0.012
regulation of body fluid levels GO:0050878 162 0.012
cytokine metabolic process GO:0042107 71 0.012
coagulation GO:0050817 78 0.012
defense response to virus GO:0051607 68 0.012
response to extracellular stimulus GO:0009991 127 0.012
positive regulation of cytokine secretion GO:0050715 41 0.011
cellular response to acid chemical GO:0071229 68 0.011
endothelial cell migration GO:0043542 44 0.011
Mouse
extracellular matrix organization GO:0030198 147 0.011
androgen biosynthetic process GO:0006702 4 0.011
response to inorganic substance GO:0010035 96 0.011
amino acid transport GO:0006865 61 0.011
regulation of cell cycle GO:0051726 281 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
endomembrane system organization GO:0010256 147 0.011
cellular amide metabolic process GO:0043603 58 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
inter male aggressive behavior GO:0002121 3 0.011
central nervous system neuron development GO:0021954 67 0.011
positive regulation of blood vessel endothelial cell migration GO:0043536 5 0.011
Mouse
cellular response to peptide hormone stimulus GO:0071375 92 0.011
ossification GO:0001503 216 0.011
protein targeting GO:0006605 143 0.011
organic hydroxy compound transport GO:0015850 93 0.011
chloride transport GO:0006821 32 0.011
positive regulation of interleukin 6 production GO:0032755 37 0.011
lipid localization GO:0010876 126 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
myelination GO:0042552 74 0.011
glucose homeostasis GO:0042593 128 0.011
cellular response to steroid hormone stimulus GO:0071383 33 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
cellular lipid metabolic process GO:0044255 323 0.011
exocytosis GO:0006887 121 0.011
positive regulation of transferase activity GO:0051347 167 0.011
detection of stimulus involved in sensory perception GO:0050906 44 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
pallium development GO:0021543 120 0.011
head morphogenesis GO:0060323 34 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
tube closure GO:0060606 91 0.010
positive regulation of defense response GO:0031349 124 0.010
regulation of neurotransmitter levels GO:0001505 87 0.010
purine ribonucleoside metabolic process GO:0046128 241 0.010
intracellular protein transport GO:0006886 204 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
positive regulation of immune effector process GO:0002699 107 0.010
negative regulation of multi organism process GO:0043901 68 0.010
regulation of neuron death GO:1901214 134 0.010
negative regulation of endopeptidase activity GO:0010951 44 0.010
protein acylation GO:0043543 64 0.010
negative regulation of iron ion transport GO:0034757 1 0.010
cellular alcohol metabolic process GO:0044107 3 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.010
hindbrain development GO:0030902 128 0.010
divalent metal ion transport GO:0070838 172 0.010
cognition GO:0050890 149 0.010
negative regulation of cytokine production GO:0001818 84 0.010
rhythmic process GO:0048511 174 0.010
toxin transport GO:1901998 38 0.010
regulation of t cell activation GO:0050863 170 0.010

Prl8a8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012