Mus musculus

39 known processes

Unc119

unc-119 homolog (C. elegans)

(Aliases: Unc119h,Rg4,Rtg4,D11Bhm52,MRG4,HRG4)

Unc119 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytoplasmic transport GO:0016482 234 0.071
peptidyl amino acid modification GO:0018193 336 0.064
Human
negative regulation of cellular component organization GO:0051129 194 0.063
microtubule based process GO:0007017 236 0.058
regulation of organelle organization GO:0033043 289 0.057
negative regulation of molecular function GO:0044092 258 0.055
regulation of cellular ketone metabolic process GO:0010565 66 0.050
regulation of cellular amine metabolic process GO:0033238 20 0.047
regulation of intracellular transport GO:0032386 159 0.046
regulation of cell projection organization GO:0031344 206 0.045
Worm
regulation of cytoplasmic transport GO:1903649 112 0.045
nucleobase containing small molecule metabolic process GO:0055086 352 0.043
nucleoside phosphate metabolic process GO:0006753 338 0.041
camera type eye development GO:0043010 266 0.041
nucleotide metabolic process GO:0009117 332 0.040
cell type specific apoptotic process GO:0097285 268 0.039
cellular ketone metabolic process GO:0042180 84 0.037
endocytosis GO:0006897 168 0.037
regulation of neuron differentiation GO:0045664 281 0.036
Worm
response to organonitrogen compound GO:0010243 246 0.036
positive regulation of transferase activity GO:0051347 167 0.032
Human
cellular amine metabolic process GO:0044106 44 0.032
negative regulation of organelle organization GO:0010639 90 0.032
nuclear division GO:0000280 158 0.031
intracellular protein transport GO:0006886 204 0.031
carbohydrate metabolic process GO:0005975 230 0.030
cellular amino acid metabolic process GO:0006520 103 0.030
blood circulation GO:0008015 195 0.030
positive regulation of cell development GO:0010720 237 0.029
regulation of protein localization GO:0032880 231 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
regulation of vesicle mediated transport GO:0060627 139 0.029
regulation of cytoskeleton organization GO:0051493 122 0.029
mapk cascade GO:0000165 281 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
apoptotic signaling pathway GO:0097190 306 0.029
dna metabolic process GO:0006259 303 0.029
purine nucleotide metabolic process GO:0006163 302 0.028
anatomical structure homeostasis GO:0060249 145 0.028
g protein coupled receptor signaling pathway GO:0007186 243 0.028
organic cyclic compound catabolic process GO:1901361 295 0.027
cellular lipid metabolic process GO:0044255 323 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
regulation of cell activation GO:0050865 289 0.027
negative regulation of phosphorus metabolic process GO:0010563 184 0.027
amine metabolic process GO:0009308 45 0.027
cell adhesion GO:0007155 329 0.027
tissue homeostasis GO:0001894 115 0.026
positive regulation of nervous system development GO:0051962 221 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.026
aromatic compound catabolic process GO:0019439 286 0.025
regulation of mapk cascade GO:0043408 248 0.025
protein maturation GO:0051604 176 0.025
cellular homeostasis GO:0019725 240 0.025
response to growth factor GO:0070848 198 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
cilium morphogenesis GO:0060271 102 0.025
Worm
cellular component assembly involved in morphogenesis GO:0010927 139 0.025
Worm
skeletal system development GO:0001501 356 0.025
cellular protein complex assembly GO:0043623 116 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.024
Human
purine containing compound metabolic process GO:0072521 311 0.024
golgi to endosome transport GO:0006895 3 0.024
carbohydrate derivative catabolic process GO:1901136 231 0.024
negative regulation of hydrolase activity GO:0051346 71 0.024
protein ubiquitination GO:0016567 171 0.024
heart process GO:0003015 94 0.024
membrane organization GO:0061024 245 0.024
hematopoietic progenitor cell differentiation GO:0002244 143 0.023
locomotory behavior GO:0007626 195 0.023
activation of immune response GO:0002253 138 0.023
regulation of transferase activity GO:0051338 263 0.023
Human
positive regulation of protein modification process GO:0031401 299 0.023
Human
regulation of protein maturation GO:1903317 96 0.023
asymmetric stem cell division GO:0098722 3 0.023
positive regulation of cell death GO:0010942 224 0.023
histone modification GO:0016570 159 0.023
regulation of hydrolase activity GO:0051336 246 0.022
immune response regulating signaling pathway GO:0002764 125 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
protein localization to organelle GO:0033365 185 0.022
regulation of proteolysis GO:0030162 164 0.022
chromatin organization GO:0006325 206 0.022
ribonucleotide metabolic process GO:0009259 291 0.021
regulation of t cell activation GO:0050863 170 0.021
forebrain development GO:0030900 302 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
oxidation reduction process GO:0055114 342 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
nucleotide catabolic process GO:0009166 217 0.021
circulatory system process GO:0003013 197 0.021
regulation of cell cycle GO:0051726 281 0.021
cellular response to cytokine stimulus GO:0071345 189 0.021
positive regulation of cell projection organization GO:0031346 95 0.021
ribose phosphate metabolic process GO:0019693 291 0.020
alcohol metabolic process GO:0006066 116 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
synaptic transmission GO:0007268 329 0.020
muscle tissue development GO:0060537 308 0.020
heart contraction GO:0060047 93 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
regulation of kinase activity GO:0043549 249 0.020
Human
macromolecule catabolic process GO:0009057 281 0.020
Worm
cytokine production GO:0001816 319 0.020
organophosphate catabolic process GO:0046434 232 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
asymmetric neuroblast division GO:0055059 1 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
retina development in camera type eye GO:0060041 119 0.019
cellular metal ion homeostasis GO:0006875 151 0.019
maintenance of location GO:0051235 89 0.019
nitrogen compound transport GO:0071705 271 0.019
neuron apoptotic process GO:0051402 142 0.019
microtubule polymerization or depolymerization GO:0031109 26 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
protein targeting GO:0006605 143 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.019
synapse organization GO:0050808 125 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.018
neural precursor cell proliferation GO:0061351 121 0.018
protein localization to nucleus GO:0034504 121 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
heterocycle catabolic process GO:0046700 280 0.018
ameboidal type cell migration GO:0001667 128 0.018
regulation of defense response GO:0031347 233 0.018
immune response activating signal transduction GO:0002757 116 0.018
meiotic cell cycle GO:0051321 122 0.018
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.018
transmembrane transport GO:0055085 412 0.018
tissue migration GO:0090130 68 0.018
cellular divalent inorganic cation homeostasis GO:0072503 127 0.018
sequestering of calcium ion GO:0051208 18 0.018
nuclear transport GO:0051169 139 0.017
nucleoside metabolic process GO:0009116 246 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
regulation of hormone levels GO:0010817 211 0.017
positive regulation of kinase activity GO:0033674 155 0.017
Human
purine ribonucleoside metabolic process GO:0046128 241 0.017
response to radiation GO:0009314 165 0.017
regulation of protein kinase activity GO:0045859 232 0.017
Human
sequestering of metal ion GO:0051238 19 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
regulation of protein transport GO:0051223 163 0.017
cellular calcium ion homeostasis GO:0006874 119 0.017
blood vessel morphogenesis GO:0048514 285 0.017
innate immune response GO:0045087 157 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
gtp catabolic process GO:0006184 143 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.016
negative regulation of proteolysis GO:0045861 74 0.016
negative regulation of phagocytosis GO:0050765 4 0.016
metal ion homeostasis GO:0055065 189 0.016
calcium ion homeostasis GO:0055074 127 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
organelle localization GO:0051640 179 0.016
regulation of cellular component size GO:0032535 121 0.016
Worm
covalent chromatin modification GO:0016569 163 0.016
regulation of binding GO:0051098 111 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
cognition GO:0050890 149 0.016
epithelium migration GO:0090132 63 0.016
morphogenesis of a branching structure GO:0001763 203 0.016
regulation of protein processing GO:0070613 96 0.016
cellular ion homeostasis GO:0006873 165 0.016
negative regulation of protein processing GO:0010955 79 0.016
positive regulation of cell activation GO:0050867 158 0.016
sensory perception GO:0007600 245 0.016
cation transport GO:0006812 399 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
developmental maturation GO:0021700 193 0.015
cation homeostasis GO:0055080 212 0.015
learning or memory GO:0007611 148 0.015
response to light stimulus GO:0009416 135 0.015
cellular chemical homeostasis GO:0055082 215 0.015
positive regulation of neuron projection development GO:0010976 79 0.015
muscle cell differentiation GO:0042692 261 0.015
regulation of ion transport GO:0043269 215 0.015
lipid localization GO:0010876 126 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
golgi vesicle transport GO:0048193 30 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
cilium assembly GO:0042384 81 0.015
Worm
glycosyl compound catabolic process GO:1901658 206 0.015
regulation of neuron apoptotic process GO:0043523 122 0.015
organelle fission GO:0048285 170 0.015
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.015
negative regulation of protein maturation GO:1903318 79 0.015
amide transport GO:0042886 138 0.015
male gamete generation GO:0048232 285 0.015
kidney development GO:0001822 213 0.015
lipid biosynthetic process GO:0008610 179 0.015
peptide secretion GO:0002790 114 0.015
cell chemotaxis GO:0060326 81 0.015
regulation of blood pressure GO:0008217 93 0.014
regulation of neuron death GO:1901214 134 0.014
negative regulation of neuron death GO:1901215 98 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
regulation of cell motility GO:2000145 236 0.014
detection of stimulus GO:0051606 84 0.014
renal system development GO:0072001 225 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
positive regulation of cell motility GO:2000147 116 0.014
regulation of secretion GO:0051046 274 0.014
t cell activation GO:0042110 289 0.014
response to organic cyclic compound GO:0014070 198 0.014
cellular response to lipid GO:0071396 145 0.014
regulation of cell migration GO:0030334 219 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
multicellular organism growth GO:0035264 161 0.014
regulation of nucleocytoplasmic transport GO:0046822 73 0.014
cation transmembrane transport GO:0098655 266 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
sulfur compound metabolic process GO:0006790 100 0.014
divalent inorganic cation transport GO:0072511 178 0.014
organelle assembly GO:0070925 177 0.013
Worm
regulation of anatomical structure size GO:0090066 178 0.013
Worm
protein processing GO:0016485 163 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
leukocyte chemotaxis GO:0030595 69 0.013
regulation of response to wounding GO:1903034 189 0.013
positive regulation of organelle organization GO:0010638 128 0.013
ras protein signal transduction GO:0007265 77 0.013
regulation of peptidase activity GO:0052547 96 0.013
neuron death GO:0070997 154 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
sensory organ morphogenesis GO:0090596 242 0.013
cholesterol metabolic process GO:0008203 56 0.013
stem cell proliferation GO:0072089 117 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
regulation of endocytosis GO:0030100 69 0.013
negative regulation of neuron apoptotic process GO:0043524 92 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
mitochondrion organization GO:0007005 134 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
inflammatory response GO:0006954 244 0.013
urogenital system development GO:0001655 261 0.013
actin filament organization GO:0007015 113 0.013
negative regulation of protein complex disassembly GO:0043242 22 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
homeostasis of number of cells GO:0048872 210 0.013
divalent metal ion transport GO:0070838 172 0.013
hormone secretion GO:0046879 128 0.013
striated muscle cell development GO:0055002 125 0.013
negative regulation of protein transport GO:0051224 46 0.013
negative regulation of homeostatic process GO:0032845 71 0.013
activation of adenylate cyclase activity GO:0007190 4 0.012
skeletal muscle organ development GO:0060538 163 0.012
negative regulation of nervous system development GO:0051961 156 0.012
Worm
carbohydrate catabolic process GO:0016052 32 0.012
rho protein signal transduction GO:0007266 32 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
Human
peptide hormone secretion GO:0030072 109 0.012
glucose homeostasis GO:0042593 128 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
wound healing GO:0042060 157 0.012
regulation of system process GO:0044057 200 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
regulation of homeostatic process GO:0032844 182 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
peptidyl serine phosphorylation GO:0018105 74 0.012
regulation of cytokine production GO:0001817 266 0.012
negative regulation of transferase activity GO:0051348 85 0.012
response to lipopolysaccharide GO:0032496 128 0.012
chromatin modification GO:0016568 187 0.012
detection of abiotic stimulus GO:0009582 60 0.012
regulation of cell cycle process GO:0010564 160 0.012
fat cell differentiation GO:0045444 160 0.012
negative regulation of immune system process GO:0002683 209 0.012
chemotaxis GO:0006935 247 0.012
regulation of protein complex disassembly GO:0043244 28 0.012
nucleoside catabolic process GO:0009164 206 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
detection of light stimulus GO:0009583 25 0.012
striated muscle tissue development GO:0014706 293 0.012
peptide transport GO:0015833 133 0.012
negative regulation of cell cycle GO:0045786 123 0.012
negative regulation of dna replication GO:0008156 4 0.012
mitotic cell cycle process GO:1903047 159 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
regulation of body fluid levels GO:0050878 162 0.012
single organism nuclear import GO:1902593 95 0.012
monosaccharide transport GO:0015749 58 0.012
axonogenesis GO:0007409 274 0.012
Worm
negative regulation of cytoskeleton organization GO:0051494 36 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
muscle system process GO:0003012 141 0.011
ion transmembrane transport GO:0034220 361 0.011
compound eye development GO:0048749 1 0.011
spermatogenesis GO:0007283 284 0.011
skin development GO:0043588 220 0.011
meiotic nuclear division GO:0007126 115 0.011
glycerolipid metabolic process GO:0046486 122 0.011
glucose transport GO:0015758 56 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
dephosphorylation GO:0016311 129 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
regulation of actin nucleation GO:0051125 4 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
hexose transport GO:0008645 56 0.011
regulation of protein binding GO:0043393 60 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
cellular response to oxidative stress GO:0034599 76 0.011
sterol metabolic process GO:0016125 58 0.011
negative regulation of cell development GO:0010721 169 0.011
Worm
pallium development GO:0021543 120 0.011
adult locomotory behavior GO:0008344 91 0.011
cyclic nucleotide metabolic process GO:0009187 59 0.011
regulation of protein complex assembly GO:0043254 83 0.011
immune effector process GO:0002252 321 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.011
heart morphogenesis GO:0003007 178 0.011
regulation of microtubule based process GO:0032886 52 0.011
response to peptide GO:1901652 136 0.011
arp2 3 complex mediated actin nucleation GO:0034314 3 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
Human
small gtpase mediated signal transduction GO:0007264 97 0.011
regulation of chromosome organization GO:0033044 83 0.011
peptidyl lysine modification GO:0018205 77 0.011
leukocyte migration GO:0050900 124 0.011
response to oxidative stress GO:0006979 123 0.011
negative regulation of peptidase activity GO:0010466 46 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
regulation of metal ion transport GO:0010959 106 0.011
sensory system development GO:0048880 3 0.011
positive regulation of defense response GO:0031349 124 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
glycoprotein metabolic process GO:0009100 116 0.010
vesicle organization GO:0016050 60 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
Human
regulation of systemic arterial blood pressure GO:0003073 61 0.010
actin polymerization or depolymerization GO:0008154 54 0.010
peptidyl serine modification GO:0018209 83 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
development of primary sexual characteristics GO:0045137 143 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.010
adult behavior GO:0030534 135 0.010
response to reactive oxygen species GO:0000302 56 0.010
negative regulation of protein modification process GO:0031400 163 0.010

Unc119 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
central nervous system disease DOID:331 0 0.016
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.012
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011
retinal disease DOID:5679 0 0.010
retinal degeneration DOID:8466 0 0.010