Mus musculus

0 known processes

Loxl3

lysyl oxidase-like 3

(Aliases: Loxl2,Lor2)

Loxl3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
extracellular matrix organization GO:0030198 147 0.222
collagen fibril organization GO:0030199 32 0.139
defense response to other organism GO:0098542 197 0.138
extracellular structure organization GO:0043062 148 0.098
response to growth factor GO:0070848 198 0.098
connective tissue development GO:0061448 179 0.090
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.082
protein processing GO:0016485 163 0.074
small gtpase mediated signal transduction GO:0007264 97 0.067
blood vessel morphogenesis GO:0048514 285 0.067
anatomical structure homeostasis GO:0060249 145 0.067
striated muscle cell development GO:0055002 125 0.067
negative regulation of molecular function GO:0044092 258 0.067
regulation of muscle tissue development GO:1901861 97 0.066
cellular amino acid metabolic process GO:0006520 103 0.066
muscle tissue development GO:0060537 308 0.064
striated muscle tissue development GO:0014706 293 0.062
ear development GO:0043583 200 0.060
thymocyte migration GO:0072679 2 0.060
cell recognition GO:0008037 83 0.060
b cell activation GO:0042113 161 0.054
cellular response to growth factor stimulus GO:0071363 197 0.052
response to acid chemical GO:0001101 111 0.052
positive regulation of thymocyte migration GO:2000412 2 0.051
regulation of proteolysis GO:0030162 164 0.050
renal system development GO:0072001 225 0.050
sensory organ morphogenesis GO:0090596 242 0.049
cellular amine metabolic process GO:0044106 44 0.048
skeletal muscle organ development GO:0060538 163 0.047
positive regulation of eosinophil migration GO:2000418 2 0.047
regulation of eosinophil migration GO:2000416 2 0.047
amine metabolic process GO:0009308 45 0.046
regulation of cellular amine metabolic process GO:0033238 20 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.042
regulation of leukocyte differentiation GO:1902105 159 0.042
positive regulation of programmed cell death GO:0043068 218 0.042
protein maturation GO:0051604 176 0.041
regulation of vesicle mediated transport GO:0060627 139 0.041
positive regulation of transferase activity GO:0051347 167 0.039
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.039
appendage development GO:0048736 166 0.039
organonitrogen compound biosynthetic process GO:1901566 192 0.039
cellular ketone metabolic process GO:0042180 84 0.039
regulation of cell adhesion GO:0030155 154 0.039
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.038
positive regulation of protein modification process GO:0031401 299 0.037
positive regulation of neuron differentiation GO:0045666 141 0.037
positive regulation of apoptotic signaling pathway GO:2001235 95 0.037
cell adhesion GO:0007155 329 0.036
multicellular organismal homeostasis GO:0048871 164 0.036
skin development GO:0043588 220 0.036
positive regulation of nervous system development GO:0051962 221 0.035
limb development GO:0060173 166 0.034
regulation of neuron projection development GO:0010975 169 0.034
forebrain development GO:0030900 302 0.034
cognition GO:0050890 149 0.034
lymphocyte differentiation GO:0030098 242 0.034
heterocycle catabolic process GO:0046700 280 0.033
oxidation reduction process GO:0055114 342 0.033
Mouse Fly
cell fate commitment GO:0045165 210 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
ossification GO:0001503 216 0.033
regulation of cytokine production GO:0001817 266 0.033
positive regulation of leukocyte differentiation GO:1902107 86 0.033
regulation of cell motility GO:2000145 236 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
negative regulation of endopeptidase activity GO:0010951 44 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
response to amino acid GO:0043200 37 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.031
ribonucleoside triphosphate metabolic process GO:0009199 220 0.031
cellular response to acid chemical GO:0071229 68 0.031
regulation of kinase activity GO:0043549 249 0.031
carbohydrate derivative catabolic process GO:1901136 231 0.031
muscle cell differentiation GO:0042692 261 0.031
immune effector process GO:0002252 321 0.030
cellular response to amino acid stimulus GO:0071230 29 0.030
myotube differentiation GO:0014902 105 0.029
purine containing compound metabolic process GO:0072521 311 0.029
response to radiation GO:0009314 165 0.029
cartilage development GO:0051216 140 0.029
Mouse
leukocyte differentiation GO:0002521 342 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
urogenital system development GO:0001655 261 0.029
regulation of cellular response to stress GO:0080135 159 0.028
glycoprotein metabolic process GO:0009100 116 0.028
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.028
cellular response to organonitrogen compound GO:0071417 145 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
covalent chromatin modification GO:0016569 163 0.027
chromatin modification GO:0016568 187 0.027
head morphogenesis GO:0060323 34 0.027
homeostasis of number of cells GO:0048872 210 0.027
regulation of cell migration GO:0030334 219 0.026
positive regulation of cell development GO:0010720 237 0.026
respiratory system development GO:0060541 190 0.026
inner ear morphogenesis GO:0042472 101 0.026
tissue homeostasis GO:0001894 115 0.026
peripheral nervous system axon regeneration GO:0014012 2 0.026
engulfment of apoptotic cell GO:0043652 3 0.026
membrane organization GO:0061024 245 0.026
organelle assembly GO:0070925 177 0.026
nucleoside catabolic process GO:0009164 206 0.026
regulation of transferase activity GO:0051338 263 0.026
lateral inhibition GO:0046331 1 0.026
extracellular matrix dependent thymocyte migration GO:0072680 1 0.026
regulation of neuron apoptotic process GO:0043523 122 0.025
biomineral tissue development GO:0031214 64 0.025
regulation of anatomical structure size GO:0090066 178 0.025
regulation of response to wounding GO:1903034 189 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
adaptive immune response GO:0002250 155 0.025
regionalization GO:0003002 337 0.024
nucleotide metabolic process GO:0009117 332 0.024
neuron apoptotic process GO:0051402 142 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
stem cell differentiation GO:0048863 268 0.024
Human
chemotaxis GO:0006935 247 0.024
regulation of cellular component biogenesis GO:0044087 181 0.024
glycosyl compound metabolic process GO:1901657 246 0.023
regulation of neuron differentiation GO:0045664 281 0.023
regulation of organelle organization GO:0033043 289 0.023
limb morphogenesis GO:0035108 149 0.023
positive regulation of endocytosis GO:0045807 42 0.023
inflammatory response GO:0006954 244 0.023
regulation of thymocyte migration GO:2000410 2 0.023
developmental maturation GO:0021700 193 0.023
ear morphogenesis GO:0042471 118 0.023
regulation of cell activation GO:0050865 289 0.023
positive regulation of cell death GO:0010942 224 0.023
eosinophil migration GO:0072677 3 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
learning GO:0007612 98 0.022
chromatin organization GO:0006325 206 0.022
production of molecular mediator of immune response GO:0002440 103 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.022
regulation of lymphocyte differentiation GO:0045619 107 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
lymphocyte apoptotic process GO:0070227 54 0.022
signal transduction in absence of ligand GO:0038034 55 0.022
response to bmp GO:0071772 14 0.022
negative regulation of protein processing GO:0010955 79 0.022
learning or memory GO:0007611 148 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.022
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.021
defense response to bacterium GO:0042742 119 0.021
skeletal muscle cell differentiation GO:0035914 66 0.021
b cell differentiation GO:0030183 78 0.021
regulation of cell projection organization GO:0031344 206 0.021
extrinsic apoptotic signaling pathway GO:0097191 126 0.021
endocytosis GO:0006897 168 0.021
axonogenesis GO:0007409 274 0.021
negative regulation of nervous system development GO:0051961 156 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
formation of primary germ layer GO:0001704 77 0.021
response to organonitrogen compound GO:0010243 246 0.020
response to oxidative stress GO:0006979 123 0.020
microtubule cytoskeleton organization GO:0000226 157 0.020
muscle fiber development GO:0048747 76 0.020
sensory perception of mechanical stimulus GO:0050954 107 0.020
organophosphate catabolic process GO:0046434 232 0.020
regulation of secretion by cell GO:1903530 249 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
cellular response to molecule of bacterial origin GO:0071219 83 0.020
antibacterial peptide production GO:0002778 2 0.020
positive regulation of proteolysis GO:0045862 85 0.020
regulation of inflammatory response GO:0050727 147 0.019
cytokine production GO:0001816 319 0.019
epithelial to mesenchymal transition GO:0001837 47 0.019
Human
negative regulation of neuron death GO:1901215 98 0.019
collagen biosynthetic process GO:0032964 7 0.019
mapk cascade GO:0000165 281 0.019
histone modification GO:0016570 159 0.019
regulation of tissue remodeling GO:0034103 38 0.019
nucleotide catabolic process GO:0009166 217 0.019
ras protein signal transduction GO:0007265 77 0.019
tendon cell differentiation GO:0035990 4 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
gastrulation GO:0007369 116 0.019
response to metal ion GO:0010038 47 0.019
mesenchymal cell differentiation GO:0048762 107 0.019
Human
response to inorganic substance GO:0010035 96 0.019
regulation of hydrolase activity GO:0051336 246 0.018
lymphocyte proliferation GO:0046651 164 0.018
cerebral cortex development GO:0021987 86 0.018
sulfur compound metabolic process GO:0006790 100 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
regulation of purine nucleotide catabolic process GO:0033121 122 0.018
regulation of homeostatic process GO:0032844 182 0.018
developmental growth involved in morphogenesis GO:0060560 138 0.018
regulation of protein processing GO:0070613 96 0.018
myoblast differentiation GO:0045445 52 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
regulation of endocytosis GO:0030100 69 0.018
positive regulation of cell activation GO:0050867 158 0.018
peripheral nervous system neuron axonogenesis GO:0048936 3 0.018
respiratory tube development GO:0030323 167 0.018
phagocytosis GO:0006909 66 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
chondrocyte differentiation GO:0002062 72 0.017
Mouse
embryonic organ morphogenesis GO:0048562 276 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
camera type eye development GO:0043010 266 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
embryonic skeletal system morphogenesis GO:0048704 91 0.017
skeletal system morphogenesis GO:0048705 203 0.017
positive regulation of neuron projection regeneration GO:0070572 2 0.017
antimicrobial peptide production GO:0002775 2 0.017
regulation of protein binding GO:0043393 60 0.017
sensory perception GO:0007600 245 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
endoderm development GO:0007492 45 0.017
glial cell differentiation GO:0010001 131 0.017
thymocyte apoptotic process GO:0070242 19 0.016
positive regulation of cellular component biogenesis GO:0044089 94 0.016
regulation of system process GO:0044057 200 0.016
dendrite development GO:0016358 115 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
carbohydrate biosynthetic process GO:0016051 74 0.016
lymphocyte mediated immunity GO:0002449 139 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
regulation of protein secretion GO:0050708 82 0.016
divalent metal ion transport GO:0070838 172 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
cellular response to lipid GO:0071396 145 0.016
regulation of rho protein signal transduction GO:0035023 71 0.016
regulation of protein maturation GO:1903317 96 0.016
cdc42 protein signal transduction GO:0032488 0 0.016
positive regulation of kinase activity GO:0033674 155 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
i kappab kinase nf kappab signaling GO:0007249 85 0.016
regulation of epithelial cell proliferation GO:0050678 141 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
lung development GO:0030324 164 0.016
peripheral nervous system development GO:0007422 53 0.016
regulation of myeloid leukocyte differentiation GO:0002761 58 0.015
cellular response to external stimulus GO:0071496 88 0.015
regulation of protein kinase activity GO:0045859 232 0.015
cellularization GO:0007349 1 0.015
regulation of cell substrate adhesion GO:0010810 73 0.015
cell type specific apoptotic process GO:0097285 268 0.015
regulation of t cell activation GO:0050863 170 0.015
spermatogenesis GO:0007283 284 0.015
angiogenesis GO:0001525 201 0.015
lipid biosynthetic process GO:0008610 179 0.015
sensory system development GO:0048880 3 0.015
rho protein signal transduction GO:0007266 32 0.015
muscle cell development GO:0055001 133 0.014
regulation of defense response GO:0031347 233 0.014
response to extracellular stimulus GO:0009991 127 0.014
microtubule based process GO:0007017 236 0.014
circulatory system process GO:0003013 197 0.014
cell matrix adhesion GO:0007160 68 0.014
epidermis development GO:0008544 187 0.014
cardiac ventricle development GO:0003231 83 0.014
regulation of cartilage development GO:0061035 44 0.014
Mouse
response to organic cyclic compound GO:0014070 198 0.014
response to oxygen levels GO:0070482 62 0.014
Mouse
antimicrobial peptide biosynthetic process GO:0002777 2 0.014
regulation of peptidase activity GO:0052547 96 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
myeloid cell homeostasis GO:0002262 114 0.014
myotube cell development GO:0014904 60 0.014
activation of mapk activity involved in innate immune response GO:0035419 2 0.014
gland development GO:0048732 330 0.014
carbohydrate metabolic process GO:0005975 230 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
negative regulation of cytokine production GO:0001818 84 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
regulation of neurotransmitter levels GO:0001505 87 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
negative regulation of neuron apoptotic process GO:0043524 92 0.014
synaptic transmission GO:0007268 329 0.014
sensory perception of sound GO:0007605 97 0.014
positive regulation of cytokine production GO:0001819 174 0.013
nucleoside metabolic process GO:0009116 246 0.013
cell proliferation in forebrain GO:0021846 30 0.013
aortic valve morphogenesis GO:0003180 4 0.013
compound eye development GO:0048749 1 0.013
fat cell differentiation GO:0045444 160 0.013
t cell apoptotic process GO:0070231 39 0.013
regulation of stress activated mapk cascade GO:0032872 69 0.013
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.013
negative regulation of protein maturation GO:1903318 79 0.013
apoptotic signaling pathway GO:0097190 306 0.013
endochondral bone morphogenesis GO:0060350 50 0.013
regulation of transmembrane transport GO:0034762 128 0.013
skeletal muscle fiber development GO:0048741 58 0.013
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.013
development of primary female sexual characteristics GO:0046545 73 0.013
female gamete generation GO:0007292 74 0.013
cellular response to bmp stimulus GO:0071773 14 0.013
regulation of cellular component size GO:0032535 121 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.013
single organism cell adhesion GO:0098602 156 0.013
organelle fission GO:0048285 170 0.013
cell substrate adhesion GO:0031589 130 0.013
regulation of mapk cascade GO:0043408 248 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
cell maturation GO:0048469 127 0.013
regulation of striated muscle cell differentiation GO:0051153 81 0.013
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.013
aromatic compound catabolic process GO:0019439 286 0.013
positive regulation of bone remodeling GO:0046852 13 0.013
protein catabolic process GO:0030163 221 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
mitochondrion distribution GO:0048311 4 0.012
leukocyte homeostasis GO:0001776 79 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
regulation of neural retina development GO:0061074 3 0.012
neuron death GO:0070997 154 0.012
cardiac chamber development GO:0003205 108 0.012
response to reactive oxygen species GO:0000302 56 0.012
digestive system development GO:0055123 200 0.012
negative regulation of proteolysis GO:0045861 74 0.012
regulation of cellular response to growth factor stimulus GO:0090287 82 0.012
leukocyte mediated immunity GO:0002443 174 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
cytokine secretion GO:0050663 72 0.012
ventricular cardiac muscle tissue development GO:0003229 38 0.012
metanephric loop of henle development GO:0072236 4 0.012
mesoderm development GO:0007498 100 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
regulation of neuron death GO:1901214 134 0.012
sequestering of metal ion GO:0051238 19 0.012
hexose biosynthetic process GO:0019319 39 0.012
negative regulation of immune system process GO:0002683 209 0.012
negative regulation of protein modification process GO:0031400 163 0.012
t cell differentiation GO:0030217 174 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
wound healing GO:0042060 157 0.012
regulation of leukocyte apoptotic process GO:2000106 56 0.012
regulation of stem cell proliferation GO:0072091 78 0.012
cellular amide metabolic process GO:0043603 58 0.012
epithelial cell development GO:0002064 159 0.012
body morphogenesis GO:0010171 45 0.012
digestive tract development GO:0048565 190 0.012
regulation of map kinase activity GO:0043405 120 0.012
sclerotome development GO:0061056 4 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
germ cell development GO:0007281 185 0.012
neurotransmitter transport GO:0006836 76 0.012
wnt signaling pathway GO:0016055 188 0.011
negative regulation of peptidase activity GO:0010466 46 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
organ regeneration GO:0031100 2 0.011
purine nucleotide metabolic process GO:0006163 302 0.011
cytoplasmic transport GO:0016482 234 0.011
negative regulation of cell migration GO:0030336 59 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
maintenance of location GO:0051235 89 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.011
cardiac ventricle morphogenesis GO:0003208 50 0.011
ovulation GO:0030728 15 0.011
t cell activation GO:0042110 289 0.011
cell junction organization GO:0034330 77 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
protein ubiquitination GO:0016567 171 0.011
peptide metabolic process GO:0006518 46 0.011
cerebellar cortex development GO:0021695 48 0.011
jnk cascade GO:0007254 72 0.011
regulation of cell size GO:0008361 72 0.011
face morphogenesis GO:0060325 29 0.011
stem cell fate determination GO:0048867 2 0.011
cardiac muscle tissue development GO:0048738 130 0.011
multi multicellular organism process GO:0044706 109 0.011
negative regulation of cell adhesion GO:0007162 45 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
epithelial cell proliferation GO:0050673 174 0.011
skeletal system development GO:0001501 356 0.011
Mouse
telencephalon development GO:0021537 186 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
regeneration GO:0031099 38 0.011
pharynx development GO:0060465 1 0.011
embryonic appendage morphogenesis GO:0035113 126 0.011
pallium development GO:0021543 120 0.011
defense response to virus GO:0051607 68 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
regulation of myotube differentiation GO:0010830 62 0.010
tissue remodeling GO:0048771 102 0.010
regulation of protein complex assembly GO:0043254 83 0.010
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.010
phagosome maturation GO:0090382 4 0.010
bone morphogenesis GO:0060349 78 0.010
regulation of cellular catabolic process GO:0031329 242 0.010
insulin processing GO:0030070 2 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
mitotic cell cycle GO:0000278 195 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
anatomical structure maturation GO:0071695 49 0.010
purine ribonucleotide metabolic process GO:0009150 290 0.010
notch signaling pathway GO:0007219 71 0.010
multicellular organismal macromolecule metabolic process GO:0044259 19 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010

Loxl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.250
musculoskeletal system disease DOID:17 0 0.250
connective tissue disease DOID:65 0 0.205
muscular disease DOID:0080000 0 0.052
myopathy DOID:423 0 0.037
muscle tissue disease DOID:66 0 0.037
nervous system disease DOID:863 0 0.030
retinal disease DOID:5679 0 0.028
retinal degeneration DOID:8466 0 0.028
sensory system disease DOID:0050155 0 0.028
eye and adnexa disease DOID:1492 0 0.028
eye disease DOID:5614 0 0.028
bone disease DOID:0080001 0 0.022
glaucoma DOID:1686 0 0.018
bone development disease DOID:0080006 0 0.016
osteochondrodysplasia DOID:2256 0 0.013
muscular dystrophy DOID:9884 0 0.012