Mus musculus

69 known processes

Pofut2

protein O-fucosyltransferase 2

(Aliases: FUT13,C21orf80,MGC25565,AI256847,MGC6943,2310011G23Rik,BC003494)

Pofut2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.131
positive regulation of protein phosphorylation GO:0001934 242 0.117
cellular response to growth factor stimulus GO:0071363 197 0.112
positive regulation of protein modification process GO:0031401 299 0.101
ossification GO:0001503 216 0.092
fat cell differentiation GO:0045444 160 0.091
skeletal system development GO:0001501 356 0.089
regulation of protein serine threonine kinase activity GO:0071900 157 0.086
regulation of ossification GO:0030278 112 0.075
extracellular structure organization GO:0043062 148 0.071
intracellular protein transport GO:0006886 204 0.068
male gamete generation GO:0048232 285 0.065
Worm
cytoplasmic transport GO:0016482 234 0.065
regulation of system process GO:0044057 200 0.065
establishment of protein localization to organelle GO:0072594 118 0.063
dna metabolic process GO:0006259 303 0.063
protein localization to organelle GO:0033365 185 0.063
g protein coupled receptor signaling pathway GO:0007186 243 0.059
response to organonitrogen compound GO:0010243 246 0.059
protein hydroxylation GO:0018126 4 0.058
carbohydrate metabolic process GO:0005975 230 0.054
negative regulation of cellular protein metabolic process GO:0032269 247 0.054
response to growth factor GO:0070848 198 0.054
macromolecule catabolic process GO:0009057 281 0.053
nucleoside phosphate metabolic process GO:0006753 338 0.052
embryonic organ morphogenesis GO:0048562 276 0.050
epithelial cell development GO:0002064 159 0.049
stem cell differentiation GO:0048863 268 0.049
negative regulation of protein metabolic process GO:0051248 282 0.048
single organism cell adhesion GO:0098602 156 0.047
biomineral tissue development GO:0031214 64 0.047
positive regulation of cell development GO:0010720 237 0.046
mapk cascade GO:0000165 281 0.045
carbohydrate derivative biosynthetic process GO:1901137 183 0.043
transmembrane transport GO:0055085 412 0.042
cell junction organization GO:0034330 77 0.042
organonitrogen compound biosynthetic process GO:1901566 192 0.042
regulation of wnt signaling pathway GO:0030111 123 0.042
wnt signaling pathway GO:0016055 188 0.041
nuclear transport GO:0051169 139 0.041
nucleotide metabolic process GO:0009117 332 0.041
glycoprotein biosynthetic process GO:0009101 89 0.038
cellular lipid metabolic process GO:0044255 323 0.038
negative regulation of protein modification process GO:0031400 163 0.038
respiratory system development GO:0060541 190 0.037
positive regulation of behavior GO:0048520 40 0.037
regulation of cell migration GO:0030334 219 0.037
negative regulation of intracellular signal transduction GO:1902532 167 0.035
cell adhesion GO:0007155 329 0.034
response to organic cyclic compound GO:0014070 198 0.033
camera type eye development GO:0043010 266 0.033
tube formation GO:0035148 140 0.032
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.032
morphogenesis of embryonic epithelium GO:0016331 159 0.032
nuclear import GO:0051170 95 0.032
response to transforming growth factor beta GO:0071559 88 0.032
spermatogenesis GO:0007283 284 0.032
Worm
wound healing GO:0042060 157 0.031
peptidyl amino acid modification GO:0018193 336 0.031
purine nucleotide metabolic process GO:0006163 302 0.030
sensory organ morphogenesis GO:0090596 242 0.030
regulation of cellular response to growth factor stimulus GO:0090287 82 0.030
positive regulation of kinase activity GO:0033674 155 0.030
regulation of body fluid levels GO:0050878 162 0.030
single organismal cell cell adhesion GO:0016337 131 0.030
response to fibroblast growth factor GO:0071774 47 0.029
bone mineralization GO:0030282 54 0.029
regulation of purine nucleotide metabolic process GO:1900542 169 0.029
regulation of mapk cascade GO:0043408 248 0.029
protein glycosylation GO:0006486 55 0.028
cellular amino acid metabolic process GO:0006520 103 0.028
cartilage development GO:0051216 140 0.028
cell growth GO:0016049 130 0.028
regulation of neuron differentiation GO:0045664 281 0.028
oxidation reduction process GO:0055114 342 0.028
morphogenesis of an epithelial sheet GO:0002011 27 0.027
regulation of kinase activity GO:0043549 249 0.027
negative regulation of wnt signaling pathway GO:0030178 73 0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
glycoprotein metabolic process GO:0009100 116 0.026
golgi vesicle transport GO:0048193 30 0.026
cellular response to hormone stimulus GO:0032870 150 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
morphogenesis of a branching epithelium GO:0061138 193 0.025
regulation of protein localization GO:0032880 231 0.025
regulation of map kinase activity GO:0043405 120 0.025
regulation of intracellular transport GO:0032386 159 0.025
antibacterial peptide biosynthetic process GO:0002780 2 0.025
positive regulation of map kinase activity GO:0043406 84 0.025
regulation of cell motility GO:2000145 236 0.025
cellular response to oxidative stress GO:0034599 76 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
chemotaxis GO:0006935 247 0.024
anatomical structure homeostasis GO:0060249 145 0.024
positive regulation of neuron differentiation GO:0045666 141 0.024
positive regulation of nervous system development GO:0051962 221 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
digestive tract development GO:0048565 190 0.023
positive regulation of transferase activity GO:0051347 167 0.023
regulation of protein kinase activity GO:0045859 232 0.023
extracellular matrix organization GO:0030198 147 0.023
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.023
muscle system process GO:0003012 141 0.023
germ cell development GO:0007281 185 0.023
nucleocytoplasmic transport GO:0006913 139 0.022
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.022
regulation of cellular amino acid metabolic process GO:0006521 5 0.022
muscle tissue development GO:0060537 308 0.022
cellular amine metabolic process GO:0044106 44 0.022
regulation of cell cycle GO:0051726 281 0.022
regulation of nucleocytoplasmic transport GO:0046822 73 0.022
blood coagulation GO:0007596 76 0.022
regulation of nucleotide metabolic process GO:0006140 169 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
response to peptide GO:1901652 136 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.022
protein import GO:0017038 101 0.022
response to oxygen levels GO:0070482 62 0.021
positive regulation of organelle organization GO:0010638 128 0.021
ras protein signal transduction GO:0007265 77 0.021
blood circulation GO:0008015 195 0.021
protein targeting GO:0006605 143 0.021
epidermis development GO:0008544 187 0.021
purine containing compound metabolic process GO:0072521 311 0.021
sphingolipid metabolic process GO:0006665 45 0.021
blood vessel morphogenesis GO:0048514 285 0.021
cation transmembrane transport GO:0098655 266 0.021
axonogenesis GO:0007409 274 0.021
response to oxidative stress GO:0006979 123 0.021
cation transport GO:0006812 399 0.020
morphogenesis of a branching structure GO:0001763 203 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
regulation of secretion GO:0051046 274 0.020
fertilization GO:0009566 127 0.020
positive regulation of cell death GO:0010942 224 0.020
skeletal system morphogenesis GO:0048705 203 0.020
axon guidance GO:0007411 141 0.019
regulation of organelle organization GO:0033043 289 0.019
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.019
regulation of defense response GO:0031347 233 0.019
positive regulation of cell motility GO:2000147 116 0.019
single organism nuclear import GO:1902593 95 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
regulation of protein transport GO:0051223 163 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
organonitrogen compound catabolic process GO:1901565 264 0.018
body morphogenesis GO:0010171 45 0.018
Worm
ion transmembrane transport GO:0034220 361 0.018
regulation of ion transport GO:0043269 215 0.018
compound eye development GO:0048749 1 0.018
negative regulation of protein phosphorylation GO:0001933 126 0.018
cellular homeostasis GO:0019725 240 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
learning or memory GO:0007611 148 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
nucleotide sugar metabolic process GO:0009225 4 0.018
epithelial tube morphogenesis GO:0060562 303 0.017
muscle cell differentiation GO:0042692 261 0.017
gland development GO:0048732 330 0.017
placenta development GO:0001890 140 0.017
glycerophospholipid metabolic process GO:0006650 71 0.017
developmental maturation GO:0021700 193 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.017
regulation of cell adhesion GO:0030155 154 0.017
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.017
cellular chemical homeostasis GO:0055082 215 0.017
response to radiation GO:0009314 165 0.017
microtubule based process GO:0007017 236 0.017
lung development GO:0030324 164 0.017
ribonucleotide catabolic process GO:0009261 208 0.016
neural tube closure GO:0001843 90 0.016
sensory perception GO:0007600 245 0.016
glycosylation GO:0070085 62 0.016
negative regulation of fat cell differentiation GO:0045599 36 0.016
protein import into nucleus GO:0006606 95 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
tissue homeostasis GO:0001894 115 0.016
oocyte construction GO:0007308 2 0.016
cellular response to lipid GO:0071396 145 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.016
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.016
coagulation GO:0050817 78 0.016
aromatic compound catabolic process GO:0019439 286 0.016
cellular response to peptide hormone stimulus GO:0071375 92 0.016
epithelial tube formation GO:0072175 130 0.016
chondrocyte differentiation GO:0002062 72 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
regulation of tight junction assembly GO:2000810 2 0.016
ameboidal type cell migration GO:0001667 128 0.016
lipid biosynthetic process GO:0008610 179 0.016
transmission of nerve impulse GO:0019226 76 0.016
regulation of fat cell differentiation GO:0045598 81 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
protein ubiquitination GO:0016567 171 0.016
regulation of protein targeting GO:1903533 61 0.016
inorganic cation transmembrane transport GO:0098662 207 0.015
defense response to other organism GO:0098542 197 0.015
maintenance of location GO:0051235 89 0.015
associative learning GO:0008306 61 0.015
protein catabolic process GO:0030163 221 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
spermatid development GO:0007286 108 0.015
regulation of anatomical structure size GO:0090066 178 0.015
glycerolipid metabolic process GO:0046486 122 0.015
synaptic transmission GO:0007268 329 0.015
negative regulation of dna replication GO:0008156 4 0.015
positive regulation of mapk cascade GO:0043410 170 0.015
neuron projection guidance GO:0097485 141 0.015
positive regulation of gene silencing by mirna GO:2000637 1 0.015
cation homeostasis GO:0055080 212 0.015
lipid transport GO:0006869 98 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
heterocycle catabolic process GO:0046700 280 0.015
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.015
cell fate commitment GO:0045165 210 0.015
regulation of cytokine production GO:0001817 266 0.015
ear development GO:0043583 200 0.015
respiratory tube development GO:0030323 167 0.015
cell cell junction organization GO:0045216 72 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
platelet activation GO:0030168 40 0.015
regulation of smad protein import into nucleus GO:0060390 3 0.015
regulation of intracellular protein transport GO:0033157 82 0.014
retina development in camera type eye GO:0060041 119 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.014
nitrogen compound transport GO:0071705 271 0.014
nucleoside catabolic process GO:0009164 206 0.014
skeletal muscle organ development GO:0060538 163 0.014
ear morphogenesis GO:0042471 118 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
glycerolipid biosynthetic process GO:0045017 50 0.014
oocyte axis specification GO:0007309 2 0.014
learning GO:0007612 98 0.014
glomerular mesangial cell proliferation GO:0072110 3 0.014
membrane organization GO:0061024 245 0.014
acetylcholine transport GO:0015870 2 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
positive regulation of proteolysis GO:0045862 85 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
digestive system development GO:0055123 200 0.014
striated muscle contraction GO:0006941 45 0.014
sensory perception of sound GO:0007605 97 0.013
antimicrobial peptide production GO:0002775 2 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
mitotic cell cycle GO:0000278 195 0.013
regulation of transferase activity GO:0051338 263 0.013
response to peptide hormone GO:0043434 127 0.013
regulation of protein catabolic process GO:0042176 108 0.013
regulation of cell projection organization GO:0031344 206 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
eye photoreceptor cell differentiation GO:0001754 41 0.013
organelle assembly GO:0070925 177 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
myotube differentiation GO:0014902 105 0.013
negative regulation of immune system process GO:0002683 209 0.013
response to inorganic substance GO:0010035 96 0.013
regulation of osteoblast differentiation GO:0045667 67 0.013
apoptotic signaling pathway GO:0097190 306 0.013
plasma lipoprotein particle clearance GO:0034381 13 0.013
lysosome organization GO:0007040 21 0.013
cell recognition GO:0008037 83 0.013
osteoclast differentiation GO:0030316 62 0.013
lipid localization GO:0010876 126 0.013
multi multicellular organism process GO:0044706 109 0.013
Worm
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.013
interleukin 8 production GO:0032637 4 0.013
cilium assembly GO:0042384 81 0.013
tube closure GO:0060606 91 0.013
molting cycle GO:0042303 90 0.013
regulation of hydrolase activity GO:0051336 246 0.013
exocrine system development GO:0035272 45 0.013
cellular modified amino acid metabolic process GO:0006575 63 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
neuron apoptotic process GO:0051402 142 0.013
purine nucleotide catabolic process GO:0006195 211 0.012
skin development GO:0043588 220 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
cognition GO:0050890 149 0.012
visual perception GO:0007601 52 0.012
positive regulation of glial cell proliferation GO:0060252 4 0.012
sulfur compound metabolic process GO:0006790 100 0.012
inner ear receptor cell development GO:0060119 39 0.012
cell junction assembly GO:0034329 52 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
regulation of lipoprotein lipase activity GO:0051004 4 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
peptidyl proline modification GO:0018208 6 0.012
cytokinetic process GO:0032506 2 0.012
regulation of hormone levels GO:0010817 211 0.012
fibroblast proliferation GO:0048144 35 0.012
heart process GO:0003015 94 0.012
lateral inhibition GO:0046331 1 0.012
basement membrane assembly GO:0070831 2 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
response to decreased oxygen levels GO:0036293 59 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
vasodilation GO:0042311 28 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
hemostasis GO:0007599 78 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
female gamete generation GO:0007292 74 0.012
striated muscle cell development GO:0055002 125 0.012
regulation of fibroblast proliferation GO:0048145 34 0.012
nucleoside metabolic process GO:0009116 246 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
neuromuscular process controlling balance GO:0050885 59 0.012
bone development GO:0060348 120 0.012
myeloid leukocyte differentiation GO:0002573 119 0.011
regulation of neuron death GO:1901214 134 0.011
regulation of proteolysis GO:0030162 164 0.011
cell type specific apoptotic process GO:0097285 268 0.011
anion transport GO:0006820 177 0.011
peptide metabolic process GO:0006518 46 0.011
regulation of canonical wnt signaling pathway GO:0060828 82 0.011
endocytosis GO:0006897 168 0.011
regulation of protein binding GO:0043393 60 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
stem cell maintenance GO:0019827 130 0.011
regulation of feeding behavior GO:0060259 3 0.011
cerebellar granule cell precursor tangential migration GO:0021935 1 0.011
actin filament organization GO:0007015 113 0.011
protein localization to membrane GO:0072657 108 0.011
substrate adhesion dependent cell spreading GO:0034446 30 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
positive regulation of protein catabolic process GO:0045732 60 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
vitamin d biosynthetic process GO:0042368 3 0.011
striated muscle tissue development GO:0014706 293 0.011
mechanoreceptor differentiation GO:0042490 67 0.011
macromolecule glycosylation GO:0043413 55 0.011
cell division GO:0051301 120 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
hindbrain development GO:0030902 128 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
forebrain development GO:0030900 302 0.011
defecation GO:0030421 1 0.011
regulation of neuron projection development GO:0010975 169 0.011
regulation of secretion by cell GO:1903530 249 0.011
response to light stimulus GO:0009416 135 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
locomotory behavior GO:0007626 195 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
regulation of cellular response to stress GO:0080135 159 0.011
early endosome to late endosome transport GO:0045022 2 0.011
negative regulation of cell development GO:0010721 169 0.011
epithelial cell migration GO:0010631 63 0.010
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.010
prevention of polyspermy GO:0060468 4 0.010
antimicrobial peptide biosynthetic process GO:0002777 2 0.010
branching morphogenesis of an epithelial tube GO:0048754 159 0.010
negative regulation of neuron death GO:1901215 98 0.010
organelle fission GO:0048285 170 0.010
cellular response to peptide GO:1901653 92 0.010
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.010
negative regulation of transferase activity GO:0051348 85 0.010
activation of adenylate cyclase activity GO:0007190 4 0.010
regulation of cellular component biogenesis GO:0044087 181 0.010
positive regulation of axon extension GO:0045773 20 0.010
response to drug GO:0042493 75 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
amine metabolic process GO:0009308 45 0.010
mesodermal cell migration GO:0008078 4 0.010
cell substrate adhesion GO:0031589 130 0.010
positive regulation of ion transport GO:0043270 65 0.010
intracellular receptor signaling pathway GO:0030522 74 0.010
positive regulation of immune effector process GO:0002699 107 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
positive regulation of innate immune response GO:0045089 80 0.010
collagen fibril organization GO:0030199 32 0.010
substrate dependent cell migration GO:0006929 18 0.010

Pofut2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
musculoskeletal system disease DOID:17 0 0.035
nervous system disease DOID:863 0 0.019
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019
disease of cellular proliferation DOID:14566 0 0.018
disease of metabolism DOID:0014667 0 0.017
eye disease DOID:5614 0 0.014
organ system cancer DOID:0050686 0 0.014
cancer DOID:162 0 0.014
retinal disease DOID:5679 0 0.013
inherited metabolic disorder DOID:655 0 0.013
connective tissue disease DOID:65 0 0.011