Mus musculus

0 known processes

Smc5

structural maintenance of chromosomes 5

(Aliases: MGC30442,SMC-5,Smc5l1,mKIAA0594,MLZ-453,MGC7569)

Smc5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular nitrogen compound catabolic process GO:0044270 280 0.168
organic cyclic compound catabolic process GO:1901361 295 0.141
aromatic compound catabolic process GO:0019439 286 0.102
mitotic cell cycle GO:0000278 195 0.100
heterocycle catabolic process GO:0046700 280 0.094
regulation of cell cycle GO:0051726 281 0.083
organelle fission GO:0048285 170 0.080
purine nucleoside triphosphate catabolic process GO:0009146 203 0.078
positive regulation of organelle organization GO:0010638 128 0.067
organophosphate catabolic process GO:0046434 232 0.066
mitotic cell cycle process GO:1903047 159 0.063
cellular amino acid metabolic process GO:0006520 103 0.062
protein localization to organelle GO:0033365 185 0.059
apoptotic signaling pathway GO:0097190 306 0.055
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
posttranscriptional regulation of gene expression GO:0010608 155 0.050
cellular ketone metabolic process GO:0042180 84 0.049
regulation of organelle organization GO:0033043 289 0.048
organelle assembly GO:0070925 177 0.046
cell division GO:0051301 120 0.046
purine ribonucleotide metabolic process GO:0009150 290 0.045
purine nucleoside triphosphate metabolic process GO:0009144 226 0.045
nucleoside triphosphate catabolic process GO:0009143 205 0.045
regulation of protein localization GO:0032880 231 0.044
gene silencing by rna GO:0031047 19 0.043
purine ribonucleoside catabolic process GO:0046130 205 0.043
small gtpase mediated signal transduction GO:0007264 97 0.042
nucleoside phosphate metabolic process GO:0006753 338 0.042
glycosyl compound metabolic process GO:1901657 246 0.041
cellular amine metabolic process GO:0044106 44 0.040
stem cell differentiation GO:0048863 268 0.039
purine nucleotide catabolic process GO:0006195 211 0.039
ras protein signal transduction GO:0007265 77 0.039
nuclear division GO:0000280 158 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.037
protein modification by small protein conjugation or removal GO:0070647 207 0.037
cellular macromolecule catabolic process GO:0044265 206 0.036
peptidyl amino acid modification GO:0018193 336 0.036
ribonucleotide catabolic process GO:0009261 208 0.036
ribonucleoside catabolic process GO:0042454 206 0.034
amine metabolic process GO:0009308 45 0.034
purine containing compound metabolic process GO:0072521 311 0.034
regulation of hydrolase activity GO:0051336 246 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
microtubule based process GO:0007017 236 0.032
regulation of intracellular transport GO:0032386 159 0.031
regulation of apoptotic signaling pathway GO:2001233 197 0.031
negative regulation of cell cycle GO:0045786 123 0.031
regulation of cellular ketone metabolic process GO:0010565 66 0.029
purine nucleoside metabolic process GO:0042278 241 0.028
immune effector process GO:0002252 321 0.028
response to molecule of bacterial origin GO:0002237 143 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
nucleoside catabolic process GO:0009164 206 0.027
cellular response to dna damage stimulus GO:0006974 207 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
nuclear transport GO:0051169 139 0.027
axonogenesis GO:0007409 274 0.026
purine ribonucleotide catabolic process GO:0009154 208 0.026
rna processing GO:0006396 105 0.026
regulation of cellular response to stress GO:0080135 159 0.025
intracellular protein transport GO:0006886 204 0.025
stem cell maintenance GO:0019827 130 0.025
glycosyl compound catabolic process GO:1901658 206 0.025
mitotic nuclear division GO:0007067 48 0.025
regulation of circadian rhythm GO:0042752 58 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.023
rho protein signal transduction GO:0007266 32 0.023
regulation of membrane potential GO:0042391 192 0.023
regulation of cell cycle process GO:0010564 160 0.023
stem cell development GO:0048864 219 0.023
mrna processing GO:0006397 63 0.022
translation GO:0006412 93 0.022
nucleotide catabolic process GO:0009166 217 0.022
morphogenesis of embryonic epithelium GO:0016331 159 0.022
ribonucleoside metabolic process GO:0009119 245 0.021
macromolecule catabolic process GO:0009057 281 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
multicellular organism growth GO:0035264 161 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
meiotic nuclear division GO:0007126 115 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
camera type eye development GO:0043010 266 0.021
microtubule cytoskeleton organization GO:0000226 157 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
response to lipopolysaccharide GO:0032496 128 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
response to radiation GO:0009314 165 0.020
endocytosis GO:0006897 168 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
regulation of cell motility GO:2000145 236 0.020
protein maturation GO:0051604 176 0.020
action potential GO:0001508 78 0.020
covalent chromatin modification GO:0016569 163 0.019
chromatin organization GO:0006325 206 0.019
neuronal action potential GO:0019228 54 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
negative regulation of molecular function GO:0044092 258 0.019
membrane organization GO:0061024 245 0.019
tube formation GO:0035148 140 0.019
cellular response to abiotic stimulus GO:0071214 56 0.019
neural precursor cell proliferation GO:0061351 121 0.019
actin cytoskeleton organization GO:0030036 220 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
regulation of protein transport GO:0051223 163 0.019
regulation of cell activation GO:0050865 289 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
regulation of translation GO:0006417 71 0.018
protein targeting GO:0006605 143 0.018
regulation of cellular amine metabolic process GO:0033238 20 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
rna splicing GO:0008380 54 0.018
positive regulation of cell cycle process GO:0090068 61 0.018
regulation of peptidase activity GO:0052547 96 0.018
cellular response to organonitrogen compound GO:0071417 145 0.017
positive regulation of cellular component biogenesis GO:0044089 94 0.017
mrna metabolic process GO:0016071 84 0.017
skin development GO:0043588 220 0.017
cellular homeostasis GO:0019725 240 0.017
cilium morphogenesis GO:0060271 102 0.017
eye photoreceptor cell differentiation GO:0001754 41 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
cell cycle checkpoint GO:0000075 47 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.017
mapk cascade GO:0000165 281 0.017
sensory perception GO:0007600 245 0.017
regulation of nuclear division GO:0051783 56 0.016
multicellular organismal signaling GO:0035637 91 0.016
regulation of cell cycle phase transition GO:1901987 77 0.016
response to organonitrogen compound GO:0010243 246 0.016
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.016
rna 3 end processing GO:0031123 20 0.016
protein import GO:0017038 101 0.016
developmental maturation GO:0021700 193 0.016
positive regulation of protein modification process GO:0031401 299 0.016
maintenance of location GO:0051235 89 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
development of primary sexual characteristics GO:0045137 143 0.016
regulation of cytokine production GO:0001817 266 0.016
chromatin modification GO:0016568 187 0.016
forebrain development GO:0030900 302 0.016
organelle localization GO:0051640 179 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
nitrogen compound transport GO:0071705 271 0.015
axon ensheathment GO:0008366 76 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
cytoplasmic transport GO:0016482 234 0.015
spermatogenesis GO:0007283 284 0.015
epithelial cell development GO:0002064 159 0.015
regulation of transcription by chromatin organization GO:0034401 0 0.015
skeletal system development GO:0001501 356 0.015
negative regulation of cell cycle process GO:0010948 69 0.015
regulation of cellular component biogenesis GO:0044087 181 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
nucleotide metabolic process GO:0009117 332 0.014
regulation of mapk cascade GO:0043408 248 0.014
leukocyte migration GO:0050900 124 0.014
cation homeostasis GO:0055080 212 0.014
ion transmembrane transport GO:0034220 361 0.014
nucleoside metabolic process GO:0009116 246 0.014
regulation of cell migration GO:0030334 219 0.014
regulation of kinase activity GO:0043549 249 0.014
cation transmembrane transport GO:0098655 266 0.013
lipid localization GO:0010876 126 0.013
primary neural tube formation GO:0014020 95 0.013
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.013
germ cell development GO:0007281 185 0.013
regulation of transferase activity GO:0051338 263 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
epithelial tube formation GO:0072175 130 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
cellular chemical homeostasis GO:0055082 215 0.013
neural tube closure GO:0001843 90 0.013
response to uv GO:0009411 44 0.013
cell junction organization GO:0034330 77 0.013
response to extracellular stimulus GO:0009991 127 0.013
response to light stimulus GO:0009416 135 0.013
fat cell differentiation GO:0045444 160 0.013
regulation of leukocyte mediated immunity GO:0002703 104 0.012
positive regulation of cell death GO:0010942 224 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
lymphocyte differentiation GO:0030098 242 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
divalent inorganic cation transport GO:0072511 178 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
dna metabolic process GO:0006259 303 0.012
heterochromatin organization GO:0070828 4 0.012
regulation of cell projection organization GO:0031344 206 0.012
transmembrane transport GO:0055085 412 0.012
oocyte axis specification GO:0007309 2 0.012
neuron death GO:0070997 154 0.012
tube closure GO:0060606 91 0.012
regulation of meiotic cell cycle GO:0051445 34 0.012
adult behavior GO:0030534 135 0.012
regulation of nucleocytoplasmic transport GO:0046822 73 0.012
ear development GO:0043583 200 0.012
body morphogenesis GO:0010171 45 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
ossification GO:0001503 216 0.011
rna phosphodiester bond hydrolysis GO:0090501 19 0.011
protein catabolic process GO:0030163 221 0.011
cellular response to insulin stimulus GO:0032869 78 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.011
neural tube formation GO:0001841 108 0.011
cation transport GO:0006812 399 0.011
cilium assembly GO:0042384 81 0.011
transmission of nerve impulse GO:0019226 76 0.011
methylation GO:0032259 134 0.011
somatic stem cell maintenance GO:0035019 47 0.011
regulation of cell shape GO:0008360 39 0.011
sister chromatid segregation GO:0000819 20 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
oocyte construction GO:0007308 2 0.011
gtp catabolic process GO:0006184 143 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
cell type specific apoptotic process GO:0097285 268 0.011
eye photoreceptor cell development GO:0042462 31 0.011
rna splicing via transesterification reactions GO:0000375 43 0.011
nuclear import GO:0051170 95 0.011
gonad development GO:0008406 141 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
circadian rhythm GO:0007623 114 0.011
purine containing compound catabolic process GO:0072523 213 0.011
negative regulation of dna replication GO:0008156 4 0.011
embryonic skeletal system development GO:0048706 120 0.011
regulation of mitotic cell cycle GO:0007346 126 0.010
epidermis development GO:0008544 187 0.010
inorganic cation transmembrane transport GO:0098662 207 0.010
regulation of system process GO:0044057 200 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
cellular response to lipid GO:0071396 145 0.010
regulation of ossification GO:0030278 112 0.010
histone modification GO:0016570 159 0.010
regulation of neuron differentiation GO:0045664 281 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
glucose homeostasis GO:0042593 128 0.010
negative regulation of mitotic cell cycle GO:0045930 58 0.010
actin filament organization GO:0007015 113 0.010

Smc5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.042
motor neuron disease DOID:231 0 0.014
central nervous system disease DOID:331 0 0.014
amyotrophic lateral sclerosis DOID:332 0 0.014
neurodegenerative disease DOID:1289 0 0.014
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012