Mus musculus

0 known processes

Smc6

structural maintenance of chromosomes 6

(Aliases: Smc6l1,AU018782,SMC-6,2810489L22Rik,mKIAA4103,KIAA4103,AW742439,AA990493,3830418C19Rik,MGC96146)

Smc6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 207 0.408
meiotic nuclear division GO:0007126 115 0.274
organic cyclic compound catabolic process GO:1901361 295 0.247
mitotic cell cycle GO:0000278 195 0.246
nucleoside triphosphate metabolic process GO:0009141 230 0.197
organophosphate catabolic process GO:0046434 232 0.191
purine ribonucleoside catabolic process GO:0046130 205 0.187
purine ribonucleotide metabolic process GO:0009150 290 0.169
organelle fission GO:0048285 170 0.158
dna repair GO:0006281 107 0.149
nucleotide metabolic process GO:0009117 332 0.147
purine nucleoside catabolic process GO:0006152 205 0.143
ribose phosphate metabolic process GO:0019693 291 0.135
nucleoside phosphate metabolic process GO:0006753 338 0.131
ribonucleotide catabolic process GO:0009261 208 0.129
nucleobase containing small molecule metabolic process GO:0055086 352 0.125
male meiosis GO:0007140 37 0.121
meiosis i GO:0007127 60 0.120
ribonucleotide metabolic process GO:0009259 291 0.119
stem cell development GO:0048864 219 0.118
purine nucleoside triphosphate catabolic process GO:0009146 203 0.114
nucleoside triphosphate catabolic process GO:0009143 205 0.111
purine ribonucleoside metabolic process GO:0046128 241 0.110
purine ribonucleotide catabolic process GO:0009154 208 0.108
heterocycle catabolic process GO:0046700 280 0.107
meiotic cell cycle process GO:1903046 77 0.105
mitotic cell cycle process GO:1903047 159 0.103
carbohydrate derivative catabolic process GO:1901136 231 0.101
purine nucleoside triphosphate metabolic process GO:0009144 226 0.100
microtubule cytoskeleton organization GO:0000226 157 0.099
chromosome segregation GO:0007059 48 0.098
cellular nitrogen compound catabolic process GO:0044270 280 0.093
organelle assembly GO:0070925 177 0.090
regulation of cell cycle process GO:0010564 160 0.090
glycosyl compound metabolic process GO:1901657 246 0.089
protein modification by small protein conjugation GO:0032446 187 0.088
microtubule organizing center organization GO:0031023 28 0.087
ribonucleoside triphosphate metabolic process GO:0009199 220 0.087
heterochromatin organization GO:0070828 4 0.085
cell division GO:0051301 120 0.084
nucleoside catabolic process GO:0009164 206 0.082
regulation of mitotic cell cycle GO:0007346 126 0.080
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.078
negative regulation of cell cycle GO:0045786 123 0.078
positive regulation of gtpase activity GO:0043547 85 0.075
nucleoside phosphate catabolic process GO:1901292 222 0.075
ras protein signal transduction GO:0007265 77 0.071
aromatic compound catabolic process GO:0019439 286 0.068
glycosyl compound catabolic process GO:1901658 206 0.068
purine nucleoside metabolic process GO:0042278 241 0.068
purine nucleotide catabolic process GO:0006195 211 0.068
microtubule based process GO:0007017 236 0.065
ribonucleoside catabolic process GO:0042454 206 0.065
protein localization to organelle GO:0033365 185 0.061
organonitrogen compound catabolic process GO:1901565 264 0.061
purine nucleotide metabolic process GO:0006163 302 0.061
regulation of cell cycle GO:0051726 281 0.061
cellular ketone metabolic process GO:0042180 84 0.059
cellular macromolecule catabolic process GO:0044265 206 0.059
positive regulation of apoptotic process GO:0043065 217 0.058
apoptotic signaling pathway GO:0097190 306 0.057
purine containing compound catabolic process GO:0072523 213 0.055
positive regulation of cell cycle process GO:0090068 61 0.054
negative regulation of protein metabolic process GO:0051248 282 0.052
ribonucleoside metabolic process GO:0009119 245 0.051
dna metabolic process GO:0006259 303 0.051
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.050
protein maturation GO:0051604 176 0.050
regulation of transcription by chromatin organization GO:0034401 0 0.050
positive regulation of cell death GO:0010942 224 0.048
neural tube development GO:0021915 160 0.047
response to radiation GO:0009314 165 0.047
purine containing compound metabolic process GO:0072521 311 0.046
development of primary sexual characteristics GO:0045137 143 0.046
ribonucleoside monophosphate metabolic process GO:0009161 80 0.045
nucleotide catabolic process GO:0009166 217 0.045
negative regulation of cell cycle phase transition GO:1901988 48 0.045
forebrain development GO:0030900 302 0.044
leukocyte differentiation GO:0002521 342 0.044
spermatogenesis GO:0007283 284 0.044
regulation of chromosome organization GO:0033044 83 0.043
meiotic cell cycle GO:0051321 122 0.043
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.041
g1 s transition of mitotic cell cycle GO:0000082 57 0.041
centrosome organization GO:0051297 26 0.041
regulation of neuron projection development GO:0010975 169 0.040
protein acylation GO:0043543 64 0.040
protein modification by small protein conjugation or removal GO:0070647 207 0.040
ribonucleoside triphosphate catabolic process GO:0009203 199 0.039
regulation of establishment of protein localization GO:0070201 181 0.039
regulation of organelle organization GO:0033043 289 0.039
spindle assembly involved in female meiosis GO:0007056 3 0.039
dna dependent dna replication GO:0006261 24 0.037
histone modification GO:0016570 159 0.037
negative regulation of dna replication GO:0008156 4 0.036
regulation of apoptotic signaling pathway GO:2001233 197 0.036
negative regulation of dna dependent dna replication GO:2000104 1 0.035
nucleoside monophosphate metabolic process GO:0009123 85 0.034
positive regulation of organelle organization GO:0010638 128 0.034
chromatin organization GO:0006325 206 0.034
dna replication GO:0006260 52 0.033
regulation of cell projection organization GO:0031344 206 0.033
epithelial tube formation GO:0072175 130 0.033
atp catabolic process GO:0006200 55 0.032
mapk cascade GO:0000165 281 0.032
protein ubiquitination GO:0016567 171 0.032
blastocyst development GO:0001824 80 0.032
lateral inhibition GO:0046331 1 0.031
regulation of nucleoside metabolic process GO:0009118 130 0.031
blood vessel morphogenesis GO:0048514 285 0.031
regulation of nucleotide metabolic process GO:0006140 169 0.031
regulation of cell cycle phase transition GO:1901987 77 0.030
rho protein signal transduction GO:0007266 32 0.030
cellular amine metabolic process GO:0044106 44 0.030
guanosine containing compound metabolic process GO:1901068 144 0.030
cellular protein catabolic process GO:0044257 155 0.029
chromosome organization involved in meiosis GO:0070192 39 0.029
camera type eye development GO:0043010 266 0.029
positive regulation of programmed cell death GO:0043068 218 0.029
regulation of neuron apoptotic process GO:0043523 122 0.029
stem cell maintenance GO:0019827 130 0.029
cellular amino acid metabolic process GO:0006520 103 0.028
nucleoside metabolic process GO:0009116 246 0.028
regulation of transferase activity GO:0051338 263 0.027
rna processing GO:0006396 105 0.027
mitotic sister chromatid segregation GO:0000070 14 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
small gtpase mediated signal transduction GO:0007264 97 0.027
gtp catabolic process GO:0006184 143 0.027
regulation of purine nucleotide metabolic process GO:1900542 169 0.027
negative regulation of cellular component organization GO:0051129 194 0.026
telomere maintenance GO:0000723 19 0.026
nucleus localization GO:0051647 20 0.026
regulation of neuron differentiation GO:0045664 281 0.026
nuclear division GO:0000280 158 0.026
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
maintenance of location GO:0051235 89 0.026
spindle assembly involved in meiosis GO:0090306 4 0.026
regulation of kinase activity GO:0043549 249 0.025
neural precursor cell proliferation GO:0061351 121 0.025
mitotic nuclear division GO:0007067 48 0.025
response to growth factor GO:0070848 198 0.025
chromatin silencing at rdna GO:0000183 3 0.025
actin mediated cell contraction GO:0070252 15 0.025
positive regulation of protein modification process GO:0031401 299 0.025
macromolecule catabolic process GO:0009057 281 0.025
lymphocyte differentiation GO:0030098 242 0.024
organelle localization GO:0051640 179 0.024
gtp metabolic process GO:0046039 144 0.024
homeostasis of number of cells GO:0048872 210 0.024
cytoplasmic transport GO:0016482 234 0.024
regulation of cellular response to stress GO:0080135 159 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
regulation of mapk cascade GO:0043408 248 0.023
guanosine containing compound catabolic process GO:1901069 144 0.023
circulatory system process GO:0003013 197 0.023
response to organonitrogen compound GO:0010243 246 0.023
epithelial tube morphogenesis GO:0060562 303 0.022
regulation of intracellular transport GO:0032386 159 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.022
compound eye development GO:0048749 1 0.022
gland development GO:0048732 330 0.022
dna recombination GO:0006310 92 0.022
oocyte axis specification GO:0007309 2 0.021
positive regulation of cytoskeleton organization GO:0051495 49 0.021
neural tube formation GO:0001841 108 0.021
ossification GO:0001503 216 0.021
regulation of protein transport GO:0051223 163 0.021
response to organic cyclic compound GO:0014070 198 0.021
negative regulation of mitotic cell cycle GO:0045930 58 0.021
regulation of cell activation GO:0050865 289 0.021
double strand break repair GO:0006302 48 0.021
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.021
negative regulation of molecular function GO:0044092 258 0.021
cell type specific apoptotic process GO:0097285 268 0.021
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.021
protein localization to nucleus GO:0034504 121 0.021
methylation GO:0032259 134 0.020
protein catabolic process GO:0030163 221 0.020
morphogenesis of embryonic epithelium GO:0016331 159 0.020
negative regulation of cell cycle process GO:0010948 69 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
gonad development GO:0008406 141 0.020
rna splicing GO:0008380 54 0.019
negative regulation of chromatin silencing GO:0031936 1 0.019
male gamete generation GO:0048232 285 0.019
regulation of protein kinase activity GO:0045859 232 0.019
regulation of membrane potential GO:0042391 192 0.019
regulation of secretion GO:0051046 274 0.019
positive regulation of apoptotic signaling pathway GO:2001235 95 0.019
dna packaging GO:0006323 30 0.019
anatomical structure homeostasis GO:0060249 145 0.019
response to light stimulus GO:0009416 135 0.019
regulation of gtp catabolic process GO:0033124 113 0.019
regulation of cellular amine metabolic process GO:0033238 20 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
regulation of cellular catabolic process GO:0031329 242 0.018
germ cell development GO:0007281 185 0.018
regulation of cell migration GO:0030334 219 0.018
myeloid cell differentiation GO:0030099 233 0.018
cellular response to abiotic stimulus GO:0071214 56 0.018
spindle organization GO:0007051 28 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.018
regulation of cell motility GO:2000145 236 0.018
regulation of chromatin silencing GO:0031935 2 0.018
axonogenesis GO:0007409 274 0.018
telomere capping GO:0016233 4 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
regulation of response to wounding GO:1903034 189 0.018
adult behavior GO:0030534 135 0.018
chromatin modification GO:0016568 187 0.018
positive regulation of cell cycle GO:0045787 92 0.018
regulation of protein localization GO:0032880 231 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
negative regulation of chromosome organization GO:2001251 30 0.017
cellular response to lipid GO:0071396 145 0.017
multi organism reproductive behavior GO:0044705 29 0.017
actin filament based movement GO:0030048 23 0.017
protein import GO:0017038 101 0.017
tube formation GO:0035148 140 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.017
atp metabolic process GO:0046034 75 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.017
leukocyte homeostasis GO:0001776 79 0.017
retina development in camera type eye GO:0060041 119 0.017
multi organism behavior GO:0051705 62 0.016
tube closure GO:0060606 91 0.016
negative regulation of gene expression epigenetic GO:0045814 15 0.016
regulation of chromatin organization GO:1902275 57 0.016
cytokine production GO:0001816 319 0.016
protein dna complex subunit organization GO:0071824 28 0.016
regulation of neuron death GO:1901214 134 0.016
mitotic cell cycle checkpoint GO:0007093 31 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
nuclear import GO:0051170 95 0.016
immune effector process GO:0002252 321 0.016
positive regulation of hydrolase activity GO:0051345 148 0.015
amine metabolic process GO:0009308 45 0.015
neural tube closure GO:0001843 90 0.015
regulation of mitotic cell cycle phase transition GO:1901990 73 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
positive regulation of kinase activity GO:0033674 155 0.015
negative regulation of protein modification process GO:0031400 163 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
skin development GO:0043588 220 0.015
skeletal system development GO:0001501 356 0.015
dendrite development GO:0016358 115 0.015
male meiosis i GO:0007141 16 0.015
multicellular organism growth GO:0035264 161 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
regulation of circadian rhythm GO:0042752 58 0.015
regulation of system process GO:0044057 200 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
respiratory system development GO:0060541 190 0.014
neuron death GO:0070997 154 0.014
regulation of response to dna damage stimulus GO:2001020 34 0.014
regulation of protein complex assembly GO:0043254 83 0.014
angiogenesis GO:0001525 201 0.014
sister chromatid segregation GO:0000819 20 0.014
muscle tissue development GO:0060537 308 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
spermatid differentiation GO:0048515 115 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
negative regulation of protein processing GO:0010955 79 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.014
cell cycle checkpoint GO:0000075 47 0.014
heterochromatin organization involved in chromatin silencing GO:0070868 1 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
regulation of nuclear division GO:0051783 56 0.014
branching morphogenesis of an epithelial tube GO:0048754 159 0.013
limb development GO:0060173 166 0.013
negative regulation of immune system process GO:0002683 209 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
regulation of dna endoreduplication GO:0032875 3 0.013
stem cell differentiation GO:0048863 268 0.013
meiotic chromosome segregation GO:0045132 19 0.013
negative regulation of neuron differentiation GO:0045665 101 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
regulation of chromatin modification GO:1903308 57 0.013
positive regulation of ras gtpase activity GO:0032320 65 0.013
protein targeting GO:0006605 143 0.013
protein processing GO:0016485 163 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
negative regulation of cell development GO:0010721 169 0.013
regulation of microtubule based process GO:0032886 52 0.013
multi multicellular organism process GO:0044706 109 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
ear development GO:0043583 200 0.013
mitotic sister chromatid cohesion GO:0007064 1 0.013
termination of rna polymerase i transcription GO:0006363 2 0.013
response to uv GO:0009411 44 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
regulation of nucleocytoplasmic transport GO:0046822 73 0.013
positive regulation of binding GO:0051099 49 0.013
leukocyte apoptotic process GO:0071887 71 0.013
positive regulation of protein localization to nucleus GO:1900182 30 0.013
cellular response to gamma radiation GO:0071480 4 0.013
regulation of b cell activation GO:0050864 81 0.013
b cell activation GO:0042113 161 0.012
regulation of protein maturation GO:1903317 96 0.012
second messenger mediated signaling GO:0019932 73 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
skeletal muscle organ development GO:0060538 163 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
negative regulation of proteolysis GO:0045861 74 0.012
rna interference GO:0016246 2 0.012
skeletal system morphogenesis GO:0048705 203 0.012
striated muscle cell development GO:0055002 125 0.012
membrane organization GO:0061024 245 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
neuron migration GO:0001764 122 0.012
axon guidance GO:0007411 141 0.012
epithelial cell development GO:0002064 159 0.012
centrosome duplication GO:0051298 16 0.012
stem cell proliferation GO:0072089 117 0.012
regulation of binding GO:0051098 111 0.012
female meiotic division GO:0007143 21 0.012
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.012
ribonucleoside monophosphate catabolic process GO:0009158 57 0.012
protein modification by small protein removal GO:0070646 21 0.012
apical constriction GO:0003383 4 0.012
meiotic sister chromatid segregation GO:0045144 6 0.012
regulation of cell shape GO:0008360 39 0.012
regulation of hydrolase activity GO:0051336 246 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
positive regulation of intracellular protein transport GO:0090316 42 0.012
regulation of protein processing GO:0070613 96 0.012
adaptive immune response GO:0002250 155 0.011
kinetochore organization GO:0051383 2 0.011
blood circulation GO:0008015 195 0.011
muscle cell differentiation GO:0042692 261 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
chemotaxis GO:0006935 247 0.011
gastrulation GO:0007369 116 0.011
cell matrix adhesion GO:0007160 68 0.011
oogenesis GO:0048477 56 0.011
primary neural tube formation GO:0014020 95 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
regulation of microtubule cytoskeleton organization GO:0070507 37 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
mitotic cytokinesis GO:0000281 4 0.011
cell maturation GO:0048469 127 0.011
covalent chromatin modification GO:0016569 163 0.011
mitotic chromosome condensation GO:0007076 1 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
intracellular protein transport GO:0006886 204 0.011
negative regulation of neuron death GO:1901215 98 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
cellular chemical homeostasis GO:0055082 215 0.011
nuclear dna replication GO:0033260 3 0.011
dna templated transcription initiation GO:0006352 13 0.011
genetic imprinting GO:0071514 27 0.010
regulation of protein localization to nucleus GO:1900180 60 0.010
regulation of defense response GO:0031347 233 0.010
heart process GO:0003015 94 0.010
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 3 0.010
maintenance of protein location in nucleus GO:0051457 2 0.010
calcium ion transport GO:0006816 159 0.010
regulation of embryonic development GO:0045995 71 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
neuron apoptotic process GO:0051402 142 0.010
epidermis development GO:0008544 187 0.010
chromatin silencing GO:0006342 15 0.010
definitive hemopoiesis GO:0060216 20 0.010
maintenance of location in cell GO:0051651 24 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
wound healing GO:0042060 157 0.010
maintenance of protein location in cell GO:0032507 20 0.010
positive regulation of protein transport GO:0051222 93 0.010
embryonic epithelial tube formation GO:0001838 130 0.010
bone development GO:0060348 120 0.010
negative regulation of b cell activation GO:0050869 27 0.010

Smc6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
breast cancer DOID:1612 0 0.026
thoracic cancer DOID:5093 0 0.026
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
sensory system disease DOID:0050155 0 0.023
eye and adnexa disease DOID:1492 0 0.022
eye disease DOID:5614 0 0.022
endocrine gland cancer DOID:170 0 0.014
central nervous system disease DOID:331 0 0.011
neurodegenerative disease DOID:1289 0 0.010