Mus musculus

14 known processes

Styx

serine/threonine/tyrosine interaction protein

(Aliases: 0610039A20Rik,hStyxb,MGC106795)

Styx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule catabolic process GO:0044265 206 0.127
dna metabolic process GO:0006259 303 0.101
spermatogenesis GO:0007283 284 0.093
spermatid differentiation GO:0048515 115 0.087
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.071
cellular ketone metabolic process GO:0042180 84 0.062
regulation of protein localization GO:0032880 231 0.058
cellular response to dna damage stimulus GO:0006974 207 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.050
protein modification by small protein conjugation GO:0032446 187 0.049
cellular amino acid metabolic process GO:0006520 103 0.049
organelle localization GO:0051640 179 0.048
macromolecule catabolic process GO:0009057 281 0.048
regulation of cell cycle process GO:0010564 160 0.047
ubiquitin dependent protein catabolic process GO:0006511 129 0.046
regulation of cell cycle GO:0051726 281 0.043
male gamete generation GO:0048232 285 0.043
organic cyclic compound catabolic process GO:1901361 295 0.040
amine metabolic process GO:0009308 45 0.039
negative regulation of intracellular signal transduction GO:1902532 167 0.039
spermatid development GO:0007286 108 0.038
negative regulation of protein metabolic process GO:0051248 282 0.038
cellular protein catabolic process GO:0044257 155 0.036
cell division GO:0051301 120 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.034
stem cell development GO:0048864 219 0.034
hematopoietic progenitor cell differentiation GO:0002244 143 0.034
protein modification by small protein conjugation or removal GO:0070647 207 0.033
regulation of intracellular transport GO:0032386 159 0.032
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
modification dependent macromolecule catabolic process GO:0043632 133 0.030
aromatic compound catabolic process GO:0019439 286 0.030
purine containing compound metabolic process GO:0072521 311 0.030
posttranscriptional regulation of gene expression GO:0010608 155 0.027
germ cell development GO:0007281 185 0.027
regulation of establishment of protein localization GO:0070201 181 0.027
protein catabolic process GO:0030163 221 0.026
protein ubiquitination GO:0016567 171 0.026
regulation of lymphocyte activation GO:0051249 240 0.026
neuron projection guidance GO:0097485 141 0.026
cellular amine metabolic process GO:0044106 44 0.026
b cell activation GO:0042113 161 0.026
stem cell differentiation GO:0048863 268 0.026
negative regulation of cell cycle GO:0045786 123 0.025
striated muscle tissue development GO:0014706 293 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
protein processing GO:0016485 163 0.024
cellular component assembly involved in morphogenesis GO:0010927 139 0.024
dna repair GO:0006281 107 0.023
regulation of mapk cascade GO:0043408 248 0.023
Human
establishment of vesicle localization GO:0051650 81 0.022
regulation of mitotic cell cycle GO:0007346 126 0.022
lymphocyte differentiation GO:0030098 242 0.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.022
peptidyl amino acid modification GO:0018193 336 0.021
homeostasis of number of cells GO:0048872 210 0.021
organelle assembly GO:0070925 177 0.021
forebrain development GO:0030900 302 0.021
apoptotic signaling pathway GO:0097190 306 0.021
transmembrane transport GO:0055085 412 0.021
translation GO:0006412 93 0.021
meiotic cell cycle process GO:1903046 77 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
regulation of cell activation GO:0050865 289 0.020
modification dependent protein catabolic process GO:0019941 133 0.020
positive regulation of protein modification process GO:0031401 299 0.020
microtubule based process GO:0007017 236 0.020
heterocycle catabolic process GO:0046700 280 0.020
regulation of cellular response to stress GO:0080135 159 0.019
positive regulation of growth GO:0045927 104 0.019
lipid localization GO:0010876 126 0.019
nitrogen compound transport GO:0071705 271 0.019
regulation of protein catabolic process GO:0042176 108 0.019
nucleotide catabolic process GO:0009166 217 0.019
membrane organization GO:0061024 245 0.019
negative regulation of synapse assembly GO:0051964 3 0.019
protein maturation GO:0051604 176 0.019
nuclear division GO:0000280 158 0.019
mapk cascade GO:0000165 281 0.018
Human
regulation of proteolysis GO:0030162 164 0.018
cell type specific apoptotic process GO:0097285 268 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
leukocyte mediated immunity GO:0002443 174 0.018
meiotic cell cycle GO:0051321 122 0.018
adaptive immune response GO:0002250 155 0.018
smoothened signaling pathway GO:0007224 105 0.018
telencephalon development GO:0021537 186 0.018
glycosyl compound metabolic process GO:1901657 246 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
fertilization GO:0009566 127 0.017
regulation of actin filament based process GO:0032970 99 0.017
nucleotide metabolic process GO:0009117 332 0.017
g1 s transition of mitotic cell cycle GO:0000082 57 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
mitotic cell cycle process GO:1903047 159 0.016
regulation of protein processing GO:0070613 96 0.016
establishment of organelle localization GO:0051656 122 0.016
cell cycle g1 s phase transition GO:0044843 57 0.016
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.016
protein localization to organelle GO:0033365 185 0.016
female sex differentiation GO:0046660 84 0.016
intracellular receptor signaling pathway GO:0030522 74 0.016
regulation of organelle organization GO:0033043 289 0.016
response to radiation GO:0009314 165 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
meiosis i GO:0007127 60 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
maintenance of location GO:0051235 89 0.016
cation transport GO:0006812 399 0.016
cellular response to organonitrogen compound GO:0071417 145 0.015
single fertilization GO:0007338 82 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
Human
ras protein signal transduction GO:0007265 77 0.015
regulation of translation GO:0006417 71 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
regulation of cell cycle phase transition GO:1901987 77 0.015
cytoplasmic transport GO:0016482 234 0.015
Human
muscle tissue development GO:0060537 308 0.015
axon guidance GO:0007411 141 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
metencephalon development GO:0022037 89 0.014
skeletal muscle organ development GO:0060538 163 0.014
cation transmembrane transport GO:0098655 266 0.014
negative regulation of cell cycle process GO:0010948 69 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
mitotic chromosome condensation GO:0007076 1 0.014
regulation of protein maturation GO:1903317 96 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
nucleobase containing small molecule metabolic process GO:0055086 352 0.014
regulation of hormone levels GO:0010817 211 0.014
actin cytoskeleton organization GO:0030036 220 0.014
lymphocyte proliferation GO:0046651 164 0.014
leukocyte differentiation GO:0002521 342 0.014
respiratory system development GO:0060541 190 0.014
organelle fission GO:0048285 170 0.014
endocytosis GO:0006897 168 0.014
chromosome segregation GO:0007059 48 0.013
negative regulation of chromatin silencing GO:0031936 1 0.013
regulation of chromosome organization GO:0033044 83 0.013
ossification GO:0001503 216 0.013
regulation of cellular protein catabolic process GO:1903362 61 0.013
regulation of t cell activation GO:0050863 170 0.013
ion transmembrane transport GO:0034220 361 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
regulation of cell projection organization GO:0031344 206 0.013
regulation of secretion GO:0051046 274 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
cytokine production GO:0001816 319 0.013
positive regulation of leukocyte differentiation GO:1902107 86 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
regulation of defense response GO:0031347 233 0.013
positive regulation of t cell activation GO:0050870 101 0.013
positive regulation of t cell differentiation GO:0045582 52 0.013
positive regulation of immature t cell proliferation GO:0033091 4 0.013
t cell differentiation in thymus GO:0033077 77 0.012
regulation of kinase activity GO:0043549 249 0.012
innate immune response GO:0045087 157 0.012
intracellular protein transport GO:0006886 204 0.012
Human
positive regulation of transferase activity GO:0051347 167 0.012
muscle cell differentiation GO:0042692 261 0.012
hindbrain development GO:0030902 128 0.012
regulation of protein stability GO:0031647 52 0.012
immune effector process GO:0002252 321 0.012
dna recombination GO:0006310 92 0.012
compound eye development GO:0048749 1 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.012
erk1 and erk2 cascade GO:0070371 77 0.012
Human
endomembrane system organization GO:0010256 147 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
regulation of membrane potential GO:0042391 192 0.012
wnt signaling pathway GO:0016055 188 0.012
mitotic cell cycle GO:0000278 195 0.012
cytokinetic process GO:0032506 2 0.012
response to light stimulus GO:0009416 135 0.012
regulation of protein ubiquitination GO:0031396 52 0.012
positive regulation of organelle organization GO:0010638 128 0.012
jak stat cascade GO:0007259 42 0.012
regulation of response to dna damage stimulus GO:2001020 34 0.011
regulation of proteasomal protein catabolic process GO:0061136 46 0.011
neuron apoptotic process GO:0051402 142 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
negative regulation of protein modification process GO:0031400 163 0.011
positive regulation of cell activation GO:0050867 158 0.011
cilium morphogenesis GO:0060271 102 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
negative regulation of dna replication GO:0008156 4 0.011
circadian regulation of gene expression GO:0032922 48 0.011
skeletal system development GO:0001501 356 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
cerebellum development GO:0021549 77 0.011
organ growth GO:0035265 117 0.011
neuron death GO:0070997 154 0.011
regulation of protein transport GO:0051223 163 0.011
positive regulation of cell motility GO:2000147 116 0.011
cognition GO:0050890 149 0.011
response to growth factor GO:0070848 198 0.011
dendrite development GO:0016358 115 0.011
amide transport GO:0042886 138 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
chemotaxis GO:0006935 247 0.011
protein acylation GO:0043543 64 0.011
adult behavior GO:0030534 135 0.011
epithelial cell migration GO:0010631 63 0.011
regulation of secretion by cell GO:1903530 249 0.010
myeloid cell differentiation GO:0030099 233 0.010
myeloid cell homeostasis GO:0002262 114 0.010
dna replication GO:0006260 52 0.010
multi organism behavior GO:0051705 62 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
mrna destabilization GO:0061157 4 0.010
t cell activation GO:0042110 289 0.010
negative regulation of proteolysis GO:0045861 74 0.010
negative regulation of gene silencing GO:0060969 2 0.010
respiratory tube development GO:0030323 167 0.010
regulation of intracellular protein transport GO:0033157 82 0.010
blood vessel morphogenesis GO:0048514 285 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
microtubule severing GO:0051013 5 0.010
cation homeostasis GO:0055080 212 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010

Styx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
muscular disease DOID:0080000 0 0.013
musculoskeletal system disease DOID:17 0 0.013
myopathy DOID:423 0 0.012
muscle tissue disease DOID:66 0 0.012
central nervous system disease DOID:331 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011