Mus musculus

0 known processes

Epc2

enhancer of polycomb homolog 2 (Drosophila)

(Aliases: D2Ertd694e,DKFZp566F2124,5830499L14)

Epc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
covalent chromatin modification GO:0016569 163 0.285
stem cell development GO:0048864 219 0.141
stem cell differentiation GO:0048863 268 0.117
peptidyl amino acid modification GO:0018193 336 0.115
development of primary sexual characteristics GO:0045137 143 0.104
protein modification by small protein conjugation or removal GO:0070647 207 0.103
chromatin modification GO:0016568 187 0.096
regulation of t cell activation GO:0050863 170 0.093
chromatin organization GO:0006325 206 0.088
rna processing GO:0006396 105 0.085
t cell activation GO:0042110 289 0.085
macromolecule methylation GO:0043414 120 0.084
cellular amino acid metabolic process GO:0006520 103 0.081
lymphocyte differentiation GO:0030098 242 0.080
methylation GO:0032259 134 0.079
regionalization GO:0003002 337 0.076
organic cyclic compound catabolic process GO:1901361 295 0.070
regulation of hydrolase activity GO:0051336 246 0.064
protein ubiquitination GO:0016567 171 0.063
t cell differentiation GO:0030217 174 0.063
protein methylation GO:0006479 81 0.062
regulation of cellular amine metabolic process GO:0033238 20 0.059
dna metabolic process GO:0006259 303 0.056
leukocyte homeostasis GO:0001776 79 0.053
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
stem cell maintenance GO:0019827 130 0.051
regulation of cellular catabolic process GO:0031329 242 0.051
regulation of transcription by chromatin organization GO:0034401 0 0.051
negative regulation of molecular function GO:0044092 258 0.046
cellular amine metabolic process GO:0044106 44 0.046
cellular response to external stimulus GO:0071496 88 0.045
amine metabolic process GO:0009308 45 0.045
regulation of peptidase activity GO:0052547 96 0.045
ribonucleotide catabolic process GO:0009261 208 0.045
ribose phosphate metabolic process GO:0019693 291 0.045
regulation of cellular ketone metabolic process GO:0010565 66 0.045
regulation of organelle organization GO:0033043 289 0.041
positive regulation of apoptotic process GO:0043065 217 0.040
regulation of feeding behavior GO:0060259 3 0.040
positive regulation of cellular amine metabolic process GO:0033240 5 0.040
positive regulation of programmed cell death GO:0043068 218 0.039
immune effector process GO:0002252 321 0.037
wnt signaling pathway GO:0016055 188 0.037
purine ribonucleoside catabolic process GO:0046130 205 0.036
camera type eye development GO:0043010 266 0.036
cell type specific apoptotic process GO:0097285 268 0.035
cellular ketone metabolic process GO:0042180 84 0.035
protein alkylation GO:0008213 81 0.035
negative regulation of cell proliferation GO:0008285 296 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
cellular response to organic cyclic compound GO:0071407 87 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
histone modification GO:0016570 159 0.034
glycosyl compound catabolic process GO:1901658 206 0.033
regulation of proteolysis GO:0030162 164 0.033
heterocycle catabolic process GO:0046700 280 0.033
spermatogenesis GO:0007283 284 0.033
protein localization to organelle GO:0033365 185 0.033
histone acetylation GO:0016573 41 0.032
respiratory system development GO:0060541 190 0.031
response to organic cyclic compound GO:0014070 198 0.031
positive regulation of protein modification process GO:0031401 299 0.030
gene silencing GO:0016458 38 0.030
signal transduction by p53 class mediator GO:0072331 51 0.030
embryonic organ morphogenesis GO:0048562 276 0.029
neural tube development GO:0021915 160 0.029
regulation of histone modification GO:0031056 56 0.029
rho protein signal transduction GO:0007266 32 0.029
nucleoside metabolic process GO:0009116 246 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.028
internal protein amino acid acetylation GO:0006475 42 0.028
carbohydrate derivative catabolic process GO:1901136 231 0.028
chromatin silencing at rdna GO:0000183 3 0.028
cilium morphogenesis GO:0060271 102 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
negative regulation of cell cycle GO:0045786 123 0.028
leukocyte differentiation GO:0002521 342 0.028
regulation of lymphocyte activation GO:0051249 240 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.027
multicellular organism growth GO:0035264 161 0.027
peptidyl lysine modification GO:0018205 77 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.027
regulation of cell cycle GO:0051726 281 0.026
cell adhesion GO:0007155 329 0.026
apoptotic signaling pathway GO:0097190 306 0.025
actin filament organization GO:0007015 113 0.025
t cell differentiation in thymus GO:0033077 77 0.025
regulation of endopeptidase activity GO:0052548 89 0.025
histone methylation GO:0016571 71 0.024
lung development GO:0030324 164 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
dendrite development GO:0016358 115 0.024
adaptive immune response GO:0002250 155 0.024
homeostasis of number of cells GO:0048872 210 0.024
cellular response to lipid GO:0071396 145 0.024
macromolecule catabolic process GO:0009057 281 0.023
immune response activating signal transduction GO:0002757 116 0.023
regulation of protein stability GO:0031647 52 0.023
regulation of cysteine type endopeptidase activity GO:2000116 65 0.023
membrane tubulation GO:0097320 4 0.023
regulation of androgen receptor signaling pathway GO:0060765 3 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
aromatic compound catabolic process GO:0019439 286 0.023
regulation of protein maturation GO:1903317 96 0.023
cilium assembly GO:0042384 81 0.023
axonogenesis GO:0007409 274 0.023
mitotic cell cycle GO:0000278 195 0.023
maintenance of location GO:0051235 89 0.022
regulation of histone methylation GO:0031060 30 0.022
nucleotide metabolic process GO:0009117 332 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
gastrulation GO:0007369 116 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.022
positive regulation of immature t cell proliferation GO:0033091 4 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.021
lymphocyte proliferation GO:0046651 164 0.021
regulation of t cell proliferation GO:0042129 92 0.021
regulation of protein kinase activity GO:0045859 232 0.021
regulation of response to alcohol GO:1901419 2 0.021
ras protein signal transduction GO:0007265 77 0.021
positive regulation of cell death GO:0010942 224 0.021
regulation of mitotic cell cycle phase transition GO:1901990 73 0.021
developmental growth involved in morphogenesis GO:0060560 138 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.020
negative regulation of chromatin silencing GO:0031936 1 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
regulation of transferase activity GO:0051338 263 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
positive regulation of organelle organization GO:0010638 128 0.020
cellular response to hormone stimulus GO:0032870 150 0.020
compound eye development GO:0048749 1 0.020
protein acylation GO:0043543 64 0.020
organelle fission GO:0048285 170 0.020
gland development GO:0048732 330 0.020
protein targeting GO:0006605 143 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
regulation of nucleoside metabolic process GO:0009118 130 0.019
b cell activation GO:0042113 161 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
cellular response to starvation GO:0009267 57 0.019
response to radiation GO:0009314 165 0.019
skeletal system morphogenesis GO:0048705 203 0.019
protein catabolic process GO:0030163 221 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
somitogenesis GO:0001756 69 0.019
regulation of leukocyte differentiation GO:1902105 159 0.018
male gamete generation GO:0048232 285 0.018
learning or memory GO:0007611 148 0.018
endocytosis GO:0006897 168 0.018
appendage development GO:0048736 166 0.018
respiratory tube development GO:0030323 167 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
regulation of cell shape GO:0008360 39 0.018
developmental maturation GO:0021700 193 0.018
regulation of cell activation GO:0050865 289 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
erk1 and erk2 cascade GO:0070371 77 0.018
regulation of intracellular transport GO:0032386 159 0.018
protein processing GO:0016485 163 0.018
embryonic epithelial tube formation GO:0001838 130 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
regulation of actin nucleation GO:0051125 4 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
positive regulation of cellular component biogenesis GO:0044089 94 0.017
regulation of lymphocyte proliferation GO:0050670 117 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
response to nutrient levels GO:0031667 109 0.017
microtubule based process GO:0007017 236 0.016
response to organonitrogen compound GO:0010243 246 0.016
sensory perception GO:0007600 245 0.016
organelle assembly GO:0070925 177 0.016
cellular response to nutrient levels GO:0031669 64 0.016
positive regulation of innate immune response GO:0045089 80 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
morphogenesis of embryonic epithelium GO:0016331 159 0.016
small molecule biosynthetic process GO:0044283 132 0.016
bmp signaling pathway GO:0030509 93 0.016
regulation of lymphocyte differentiation GO:0045619 107 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
regulation of mapk cascade GO:0043408 248 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
neural tube closure GO:0001843 90 0.016
intracellular receptor signaling pathway GO:0030522 74 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
protein maturation GO:0051604 176 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
negative regulation of protein metabolic process GO:0051248 282 0.015
pharynx development GO:0060465 1 0.015
organic acid biosynthetic process GO:0016053 86 0.015
transmembrane transport GO:0055085 412 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
regulation of hormone levels GO:0010817 211 0.015
regulation of nucleocytoplasmic transport GO:0046822 73 0.015
negative regulation of protein maturation GO:1903318 79 0.015
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
limb morphogenesis GO:0035108 149 0.015
neuron death GO:0070997 154 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
regulation of cell adhesion GO:0030155 154 0.014
organophosphate catabolic process GO:0046434 232 0.014
organelle localization GO:0051640 179 0.014
mesodermal cell migration GO:0008078 4 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
negative regulation of protein modification process GO:0031400 163 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
intracellular protein transport GO:0006886 204 0.014
cognition GO:0050890 149 0.014
positive regulation of macroautophagy GO:0016239 3 0.014
protein localization to vacuole GO:0072665 4 0.014
leukocyte proliferation GO:0070661 172 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
activation of immune response GO:0002253 138 0.014
regulation of protein processing GO:0070613 96 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
protein targeting to vacuole GO:0006623 3 0.014
cellular protein catabolic process GO:0044257 155 0.014
regulation of chromatin modification GO:1903308 57 0.014
regulation of t cell differentiation GO:0045580 83 0.014
organic hydroxy compound transport GO:0015850 93 0.014
forebrain development GO:0030900 302 0.014
fertilization GO:0009566 127 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
tube formation GO:0035148 140 0.014
endomembrane system organization GO:0010256 147 0.014
regulation of cell motility GO:2000145 236 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
embryonic placenta development GO:0001892 98 0.014
negative regulation of hydrolase activity GO:0051346 71 0.014
placenta development GO:0001890 140 0.014
regulation of kinase activity GO:0043549 249 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
regulation of bmp signaling pathway GO:0030510 60 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
defense response to other organism GO:0098542 197 0.013
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.013
regulation of cell cycle process GO:0010564 160 0.013
cytokine mediated signaling pathway GO:0019221 115 0.013
regulation of genetic imprinting GO:2000653 5 0.013
female meiosis chromosome segregation GO:0016321 1 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
regulation of leukocyte proliferation GO:0070663 121 0.013
negative regulation of anoikis GO:2000811 2 0.013
negative regulation of ras protein signal transduction GO:0046580 18 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
glucose homeostasis GO:0042593 128 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
blood circulation GO:0008015 195 0.013
female gamete generation GO:0007292 74 0.013
t cell proliferation GO:0042098 120 0.013
regulation of secretion GO:0051046 274 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
sensory organ morphogenesis GO:0090596 242 0.013
membrane organization GO:0061024 245 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
response to inorganic substance GO:0010035 96 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
genitalia development GO:0048806 37 0.013
establishment of protein localization to vacuole GO:0072666 4 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
cation transmembrane transport GO:0098655 266 0.013
positive regulation of cell activation GO:0050867 158 0.012
regulation of cytokine production GO:0001817 266 0.012
muscle tissue development GO:0060537 308 0.012
regulation of ion transport GO:0043269 215 0.012
b cell homeostasis GO:0001782 34 0.012
negative regulation of cell development GO:0010721 169 0.012
positive regulation of growth GO:0045927 104 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
cellular lipid metabolic process GO:0044255 323 0.012
neural tube formation GO:0001841 108 0.012
multi multicellular organism process GO:0044706 109 0.012
receptor mediated endocytosis GO:0006898 51 0.012
mitotic cell cycle process GO:1903047 159 0.012
feeding behavior GO:0007631 62 0.012
digestive system development GO:0055123 200 0.012
carbohydrate metabolic process GO:0005975 230 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.012
actomyosin structure organization GO:0031032 56 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
cytoplasmic transport GO:0016482 234 0.012
mrna metabolic process GO:0016071 84 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
regulation of neuron differentiation GO:0045664 281 0.012
exocytosis GO:0006887 121 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
regulation of cell cycle phase transition GO:1901987 77 0.012
regulation of neuron death GO:1901214 134 0.012
angiogenesis GO:0001525 201 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
actin cytoskeleton organization GO:0030036 220 0.012
purine containing compound metabolic process GO:0072521 311 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
blood vessel morphogenesis GO:0048514 285 0.011
actin filament polymerization GO:0030041 44 0.011
glycoprotein metabolic process GO:0009100 116 0.011
sensory perception of sound GO:0007605 97 0.011
histone h3 k9 methylation GO:0051567 17 0.011
regulation of transmembrane transport GO:0034762 128 0.011
germ cell development GO:0007281 185 0.011
peptidyl lysine methylation GO:0018022 29 0.011
negative regulation of cell cycle process GO:0010948 69 0.011
ion transmembrane transport GO:0034220 361 0.011
b cell differentiation GO:0030183 78 0.011
cellularization GO:0007349 1 0.011
negative regulation of mapk cascade GO:0043409 65 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
regulation of binding GO:0051098 111 0.011
leukocyte apoptotic process GO:0071887 71 0.011
endothelial cell differentiation GO:0045446 41 0.011
epithelial tube formation GO:0072175 130 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
cell division GO:0051301 120 0.011
positive regulation of peptidase activity GO:0010952 49 0.011
renal system development GO:0072001 225 0.011
histone lysine methylation GO:0034968 50 0.011
nuclear import GO:0051170 95 0.011
positive regulation of nervous system development GO:0051962 221 0.011
axon guidance GO:0007411 141 0.011
digestive tract morphogenesis GO:0048546 147 0.011
somite development GO:0061053 81 0.010
tubulin deacetylation GO:0090042 4 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.010
chemotaxis GO:0006935 247 0.010
cation transport GO:0006812 399 0.010
skeletal system development GO:0001501 356 0.010
single organismal cell cell adhesion GO:0016337 131 0.010
positive regulation of camp dependent protein kinase activity GO:2000481 3 0.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.010
apical constriction GO:0003383 4 0.010
carbohydrate homeostasis GO:0033500 128 0.010
actin filament bundle assembly GO:0051017 40 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.010
circadian rhythm GO:0007623 114 0.010
blastocyst development GO:0001824 80 0.010
bone morphogenesis GO:0060349 78 0.010
sequestering of calcium ion GO:0051208 18 0.010
striated muscle tissue development GO:0014706 293 0.010
epithelial cell development GO:0002064 159 0.010
regulation of leukocyte mediated immunity GO:0002703 104 0.010
mapk cascade GO:0000165 281 0.010
cell maturation GO:0048469 127 0.010
nucleotide catabolic process GO:0009166 217 0.010
nuclear division GO:0000280 158 0.010

Epc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.045
large intestine cancer DOID:5672 0 0.045
colon cancer DOID:219 0 0.045
gastrointestinal system cancer DOID:3119 0 0.045
cancer DOID:162 0 0.045
organ system cancer DOID:0050686 0 0.045
intestinal cancer DOID:10155 0 0.045
colorectal cancer DOID:9256 0 0.045
nervous system disease DOID:863 0 0.030
disease of anatomical entity DOID:7 0 0.030
endocrine gland cancer DOID:170 0 0.024
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
colon carcinoma DOID:1520 0 0.011
eye disease DOID:5614 0 0.011
central nervous system disease DOID:331 0 0.011
thoracic cancer DOID:5093 0 0.011