Mus musculus

146 known processes

Slfn1

schlafen 1

(Aliases: AV316259)

Slfn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response to other organism GO:0098542 197 0.835
neutrophil chemotaxis GO:0030593 36 0.820
positive regulation of defense response GO:0031349 124 0.663
leukocyte migration GO:0050900 124 0.630
leukocyte chemotaxis GO:0030595 69 0.596
rho protein signal transduction GO:0007266 32 0.550
neutrophil migration GO:1990266 37 0.514
granulocyte migration GO:0097530 43 0.493
positive regulation of neutrophil chemotaxis GO:0090023 12 0.473
chemotaxis GO:0006935 247 0.432
response to molecule of bacterial origin GO:0002237 143 0.407
regulation of defense response GO:0031347 233 0.399
cell chemotaxis GO:0060326 81 0.391
defense response to bacterium GO:0042742 119 0.370
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.361
innate immune response GO:0045087 157 0.358
granulocyte chemotaxis GO:0071621 39 0.334
positive regulation of granulocyte chemotaxis GO:0071624 12 0.331
defense response to gram positive bacterium GO:0050830 50 0.329
regulation of cell motility GO:2000145 236 0.329
immune effector process GO:0002252 321 0.326
positive regulation of cytokine production GO:0001819 174 0.310
cytokine production GO:0001816 319 0.304
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.294
glycosyl compound catabolic process GO:1901658 206 0.258
regulation of lymphocyte activation GO:0051249 240 0.256
positive regulation of cell migration GO:0030335 109 0.254
myeloid leukocyte migration GO:0097529 57 0.250
immune response regulating signaling pathway GO:0002764 125 0.243
second messenger mediated signaling GO:0019932 73 0.243
cellular homeostasis GO:0019725 240 0.242
positive regulation of chemotaxis GO:0050921 38 0.240
regulation of response to wounding GO:1903034 189 0.235
stress activated protein kinase signaling cascade GO:0031098 81 0.229
myeloid cell differentiation GO:0030099 233 0.218
cation homeostasis GO:0055080 212 0.211
leukocyte activation involved in immune response GO:0002366 126 0.201
t cell activation involved in immune response GO:0002286 43 0.196
positive regulation of macrophage chemotaxis GO:0010759 5 0.194
pattern recognition receptor signaling pathway GO:0002221 47 0.193
t cell activation GO:0042110 289 0.193
regulation of innate immune response GO:0045088 91 0.192
cell activation involved in immune response GO:0002263 126 0.192
regulation of protein localization GO:0032880 231 0.175
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.169
innate immune response activating signal transduction GO:0002758 50 0.168
positive regulation of cellular amine metabolic process GO:0033240 5 0.166
ras protein signal transduction GO:0007265 77 0.166
t cell proliferation GO:0042098 120 0.154
regulation of cell migration GO:0030334 219 0.154
response to lipopolysaccharide GO:0032496 128 0.149
inflammatory response GO:0006954 244 0.146
cellular response to cytokine stimulus GO:0071345 189 0.146
negative regulation of cytokine production GO:0001818 84 0.146
t cell differentiation GO:0030217 174 0.145
regulation of homeostatic process GO:0032844 182 0.145
regulation of neutrophil chemotaxis GO:0090022 14 0.143
cellular ion homeostasis GO:0006873 165 0.142
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.142
ribose phosphate metabolic process GO:0019693 291 0.141
regulation of granulocyte chemotaxis GO:0071622 17 0.141
ameboidal type cell migration GO:0001667 128 0.139
mapk cascade GO:0000165 281 0.138
activation of innate immune response GO:0002218 56 0.136
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.133
positive regulation of innate immune response GO:0045089 80 0.130
nucleotide metabolic process GO:0009117 332 0.129
positive regulation of lymphocyte proliferation GO:0050671 70 0.127
lymphocyte differentiation GO:0030098 242 0.126
apoptotic signaling pathway GO:0097190 306 0.123
regulation of leukocyte proliferation GO:0070663 121 0.122
positive regulation of cell motility GO:2000147 116 0.122
positive regulation of leukocyte differentiation GO:1902107 86 0.121
blood vessel morphogenesis GO:0048514 285 0.119
positive regulation of inflammatory response GO:0050729 47 0.119
regulation of cytokine production GO:0001817 266 0.118
keratinocyte migration GO:0051546 3 0.118
g protein coupled receptor signaling pathway GO:0007186 243 0.118
cellular amino acid metabolic process GO:0006520 103 0.118
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.118
cell adhesion GO:0007155 329 0.116
organonitrogen compound catabolic process GO:1901565 264 0.114
cellular response to lipopolysaccharide GO:0071222 77 0.114
metal ion homeostasis GO:0055065 189 0.113
positive regulation of protein phosphorylation GO:0001934 242 0.112
purine nucleotide catabolic process GO:0006195 211 0.112
myeloid leukocyte differentiation GO:0002573 119 0.112
cellular response to biotic stimulus GO:0071216 92 0.111
small gtpase mediated signal transduction GO:0007264 97 0.110
mononuclear cell migration GO:0071674 8 0.110
regulation of chemokine production GO:0032642 30 0.107
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.107
jnk cascade GO:0007254 72 0.107
leukocyte mediated immunity GO:0002443 174 0.105
glycosyl compound metabolic process GO:1901657 246 0.104
positive regulation of cell activation GO:0050867 158 0.104
divalent inorganic cation homeostasis GO:0072507 138 0.104
interferon gamma production GO:0032609 67 0.102
negative regulation of immune system process GO:0002683 209 0.101
positive regulation of lymphocyte activation GO:0051251 140 0.101
purine ribonucleotide metabolic process GO:0009150 290 0.100
reactive nitrogen species metabolic process GO:2001057 0 0.099
positive regulation of immune effector process GO:0002699 107 0.097
regulation of transferase activity GO:0051338 263 0.097
regulation of hormone levels GO:0010817 211 0.096
interspecies interaction between organisms GO:0044419 83 0.096
regulation of vesicle mediated transport GO:0060627 139 0.096
nucleobase containing small molecule metabolic process GO:0055086 352 0.095
regulation of toll like receptor signaling pathway GO:0034121 20 0.095
adaptive immune response GO:0002250 155 0.093
positive regulation of behavior GO:0048520 40 0.093
amine metabolic process GO:0009308 45 0.092
alpha beta t cell activation involved in immune response GO:0002287 31 0.091
cell killing GO:0001906 67 0.091
cytokine secretion GO:0050663 72 0.090
negative regulation of cell proliferation GO:0008285 296 0.089
angiogenesis GO:0001525 201 0.088
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.088
regulation of adaptive immune response GO:0002819 90 0.088
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.087
leukocyte differentiation GO:0002521 342 0.087
cellular response to lipid GO:0071396 145 0.087
positive regulation of apoptotic process GO:0043065 217 0.087
regulation of multi organism process GO:0043900 111 0.086
positive regulation of neutrophil migration GO:1902624 12 0.085
regulation of neutrophil migration GO:1902622 14 0.085
regulation of interleukin 8 production GO:0032677 3 0.084
positive regulation of hydrolase activity GO:0051345 148 0.084
single organismal cell cell adhesion GO:0016337 131 0.084
regulation of cellular component biogenesis GO:0044087 181 0.084
regulation of t cell activation GO:0050863 170 0.083
purine nucleoside triphosphate catabolic process GO:0009146 203 0.082
peptide transport GO:0015833 133 0.082
regulation of leukocyte mediated immunity GO:0002703 104 0.080
regulation of inflammatory response GO:0050727 147 0.080
immune response activating signal transduction GO:0002757 116 0.079
ribonucleoside catabolic process GO:0042454 206 0.079
ribonucleotide metabolic process GO:0009259 291 0.078
macrophage chemotaxis GO:0048246 14 0.078
cellular chemical homeostasis GO:0055082 215 0.077
purine containing compound catabolic process GO:0072523 213 0.077
t helper 17 cell chemotaxis GO:0035705 1 0.076
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.076
regulation of stress activated mapk cascade GO:0032872 69 0.075
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.075
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.074
nucleoside phosphate metabolic process GO:0006753 338 0.074
regulation of cellular ketone metabolic process GO:0010565 66 0.073
cation transport GO:0006812 399 0.072
positive regulation of t cell activation GO:0050870 101 0.071
signal transduction in absence of ligand GO:0038034 55 0.071
alpha beta t cell proliferation GO:0046633 21 0.071
leukocyte cell cell adhesion GO:0007159 14 0.070
cellular extravasation GO:0045123 17 0.070
positive regulation of t cell extravasation GO:2000409 2 0.070
regulation of chemotaxis GO:0050920 53 0.070
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.070
fat cell differentiation GO:0045444 160 0.069
regulation of reactive oxygen species metabolic process GO:2000377 40 0.069
cellular divalent inorganic cation homeostasis GO:0072503 127 0.068
negative regulation of multi organism process GO:0043901 68 0.068
nucleoside metabolic process GO:0009116 246 0.067
carbohydrate derivative catabolic process GO:1901136 231 0.067
protein catabolic process GO:0030163 221 0.067
cytokine mediated signaling pathway GO:0019221 115 0.066
regulation of monocyte chemotaxis GO:0090025 3 0.066
regulation of cytokine biosynthetic process GO:0042035 59 0.066
maintenance of location GO:0051235 89 0.065
regulation of cellular amino acid metabolic process GO:0006521 5 0.064
regulation of mapk cascade GO:0043408 248 0.063
positive regulation of homeostatic process GO:0032846 64 0.063
t cell differentiation involved in immune response GO:0002292 30 0.063
positive regulation of monocyte chemotaxis GO:0090026 2 0.063
ribonucleoside metabolic process GO:0009119 245 0.062
regulation of t cell differentiation GO:0045580 83 0.061
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.060
activation of immune response GO:0002253 138 0.060
regulation of secretion GO:0051046 274 0.060
calcium ion homeostasis GO:0055074 127 0.060
guanosine containing compound catabolic process GO:1901069 144 0.059
myotube differentiation GO:0014902 105 0.059
cellular response to molecule of bacterial origin GO:0071219 83 0.059
regulation of jnk cascade GO:0046328 62 0.058
positive regulation of cell death GO:0010942 224 0.058
response to interferon gamma GO:0034341 34 0.058
positive regulation of cytokine biosynthetic process GO:0042108 40 0.058
nucleotide catabolic process GO:0009166 217 0.058
leukocyte proliferation GO:0070661 172 0.058
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.058
positive regulation of secretion GO:0051047 130 0.057
modification of morphology or physiology of other organism GO:0035821 18 0.057
regulation of protein serine threonine kinase activity GO:0071900 157 0.057
regulation of protein transport GO:0051223 163 0.056
regulation of interferon gamma production GO:0032649 57 0.056
purine nucleotide metabolic process GO:0006163 302 0.056
regulation of angiogenesis GO:0045765 81 0.056
lymphocyte mediated immunity GO:0002449 139 0.056
cytosolic calcium ion transport GO:0060401 48 0.056
purine ribonucleoside metabolic process GO:0046128 241 0.056
regulation of lymphocyte mediated immunity GO:0002706 84 0.055
reactive oxygen species metabolic process GO:0072593 84 0.055
skeletal muscle organ development GO:0060538 163 0.055
aromatic compound catabolic process GO:0019439 286 0.055
negative regulation of protein metabolic process GO:0051248 282 0.055
regulation of ras protein signal transduction GO:0046578 114 0.055
positive regulation of immunological synapse formation GO:2000522 1 0.054
interleukin 1 production GO:0032612 31 0.054
purine containing compound metabolic process GO:0072521 311 0.054
nucleoside triphosphate metabolic process GO:0009141 230 0.053
carbohydrate derivative biosynthetic process GO:1901137 183 0.053
regulation of t cell proliferation GO:0042129 92 0.053
lymphocyte activation involved in immune response GO:0002285 93 0.053
defense response to gram negative bacterium GO:0050829 28 0.053
i kappab kinase nf kappab signaling GO:0007249 85 0.052
positive regulation of nucleotide metabolic process GO:0045981 114 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.052
purine nucleoside catabolic process GO:0006152 205 0.052
cellular nitrogen compound catabolic process GO:0044270 280 0.052
platelet activation GO:0030168 40 0.052
wound healing GO:0042060 157 0.052
peptide secretion GO:0002790 114 0.051
regulation of vascular endothelial growth factor production GO:0010574 13 0.051
actin cytoskeleton organization GO:0030036 220 0.051
muscle cell differentiation GO:0042692 261 0.051
immunoglobulin mediated immune response GO:0016064 69 0.050
nitrogen compound transport GO:0071705 271 0.050
heterocycle catabolic process GO:0046700 280 0.049
regulation of map kinase activity GO:0043405 120 0.049
purine nucleoside triphosphate metabolic process GO:0009144 226 0.049
interaction with symbiont GO:0051702 14 0.049
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.049
sequestering of metal ion GO:0051238 19 0.048
interferon beta biosynthetic process GO:0045350 4 0.048
negative regulation of synapse assembly GO:0051964 3 0.048
regulation of nucleotide metabolic process GO:0006140 169 0.047
positive regulation of transferase activity GO:0051347 167 0.047
response to organonitrogen compound GO:0010243 246 0.047
syncytium formation by plasma membrane fusion GO:0000768 42 0.047
glycoprotein biosynthetic process GO:0009101 89 0.046
calcium mediated signaling GO:0019722 46 0.046
divalent inorganic cation transport GO:0072511 178 0.046
mature dendritic cell differentiation GO:0097029 3 0.046
positive regulation of mapk cascade GO:0043410 170 0.046
cellular metal ion homeostasis GO:0006875 151 0.046
positive regulation of protein kinase activity GO:0045860 144 0.046
cellular calcium ion homeostasis GO:0006874 119 0.045
positive regulation of granulocyte macrophage colony stimulating factor production GO:0032725 3 0.045
amide transport GO:0042886 138 0.045
regulation of cellular response to stress GO:0080135 159 0.045
negative regulation of intracellular signal transduction GO:1902532 167 0.045
negative regulation of growth GO:0045926 99 0.045
purine nucleoside metabolic process GO:0042278 241 0.045
regulation of protein kinase activity GO:0045859 232 0.045
regulation of phospholipase c activity GO:1900274 3 0.044
positive regulation of interferon gamma production GO:0032729 39 0.044
gland development GO:0048732 330 0.044
cellular ketone metabolic process GO:0042180 84 0.044
negative regulation of homeostatic process GO:0032845 71 0.044
regulation of establishment of protein localization GO:0070201 181 0.044
organic cyclic compound catabolic process GO:1901361 295 0.043
response to acid chemical GO:0001101 111 0.043
nucleoside triphosphate catabolic process GO:0009143 205 0.043
negative regulation of response to wounding GO:1903035 77 0.043
ribonucleoside triphosphate metabolic process GO:0009199 220 0.043
blood coagulation GO:0007596 76 0.043
homeostasis of number of cells GO:0048872 210 0.042
alpha beta t cell differentiation GO:0046632 69 0.042
organophosphate catabolic process GO:0046434 232 0.042
multicellular organismal homeostasis GO:0048871 164 0.042
epithelial cell proliferation GO:0050673 174 0.041
ribonucleoside triphosphate catabolic process GO:0009203 199 0.041
protein modification by small protein conjugation GO:0032446 187 0.041
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.041
macromolecule catabolic process GO:0009057 281 0.041
positive regulation of programmed cell death GO:0043068 218 0.041
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.041
extrinsic apoptotic signaling pathway GO:0097191 126 0.041
alpha beta t cell activation GO:0046631 91 0.041
regulation of cell activation GO:0050865 289 0.041
production of molecular mediator of immune response GO:0002440 103 0.040
vascular endothelial growth factor production GO:0010573 13 0.040
positive regulation of jnk cascade GO:0046330 46 0.040
cognition GO:0050890 149 0.040
membrane organization GO:0061024 245 0.040
carbohydrate metabolic process GO:0005975 230 0.040
chemokine mediated signaling pathway GO:0070098 17 0.040
learning or memory GO:0007611 148 0.039
regulation of peptide transport GO:0090087 91 0.039
negative regulation of cell activation GO:0050866 111 0.039
activation of mapk activity GO:0000187 59 0.039
sequestering of calcium ion GO:0051208 18 0.039
b cell mediated immunity GO:0019724 71 0.039
positive regulation of angiogenesis GO:0045766 46 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.039
compound eye development GO:0048749 1 0.039
single organism cell adhesion GO:0098602 156 0.038
stress activated mapk cascade GO:0051403 80 0.038
purine ribonucleoside catabolic process GO:0046130 205 0.038
cytoplasmic transport GO:0016482 234 0.038
regulation of alpha beta t cell proliferation GO:0046640 18 0.038
divalent metal ion transport GO:0070838 172 0.038
regulation of lymphocyte proliferation GO:0050670 117 0.038
positive regulation of cell development GO:0010720 237 0.038
helper t cell chemotaxis GO:0035704 1 0.038
reactive oxygen species biosynthetic process GO:1903409 8 0.037
neutrophil mediated killing of symbiont cell GO:0070943 8 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.037
regulation of protein import into nucleus GO:0042306 52 0.037
ribonucleotide catabolic process GO:0009261 208 0.037
positive regulation of cellular component biogenesis GO:0044089 94 0.037
tolerance induction GO:0002507 14 0.036
gtp metabolic process GO:0046039 144 0.036
interleukin 8 production GO:0032637 4 0.036
circulatory system process GO:0003013 197 0.036
muscle tissue development GO:0060537 308 0.036
negative regulation of growth of symbiont in host GO:0044130 19 0.036
intracellular protein transport GO:0006886 204 0.036
positive regulation of leukocyte proliferation GO:0070665 73 0.036
guanosine containing compound metabolic process GO:1901068 144 0.035
leukocyte mediated cytotoxicity GO:0001909 62 0.035
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.035
regulation of lymphocyte differentiation GO:0045619 107 0.035
defense response to virus GO:0051607 68 0.035
energy derivation by oxidation of organic compounds GO:0015980 77 0.035
peptidyl amino acid modification GO:0018193 336 0.035
insulin secretion GO:0030073 89 0.035
regulation of peptide secretion GO:0002791 77 0.035
regulation of endocytosis GO:0030100 69 0.035
growth involved in symbiotic interaction GO:0044110 23 0.034
morphogenesis of a branching structure GO:0001763 203 0.034
regulation of tumor necrosis factor production GO:0032680 49 0.034
negative regulation of t cell activation GO:0050868 65 0.034
anatomical structure homeostasis GO:0060249 145 0.034
negative regulation of lymphocyte activation GO:0051250 91 0.034
neuron migration GO:0001764 122 0.034
response to molecule of fungal origin GO:0002238 4 0.034
tissue homeostasis GO:0001894 115 0.033
regulation of purine nucleotide metabolic process GO:1900542 169 0.033
lymphocyte proliferation GO:0046651 164 0.033
regulation of body fluid levels GO:0050878 162 0.033
positive regulation of cytokine secretion GO:0050715 41 0.033
regulation of nucleoside metabolic process GO:0009118 130 0.032
oxidation reduction process GO:0055114 342 0.032
epithelial cell migration GO:0010631 63 0.032
regulation of lipid metabolic process GO:0019216 118 0.032
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.032
leukocyte apoptotic process GO:0071887 71 0.032
regulation of jun kinase activity GO:0043506 40 0.032
cellular amine metabolic process GO:0044106 44 0.032
regulation of ion transport GO:0043269 215 0.032
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.032
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.031
regulation of type 2 immune response GO:0002828 18 0.031
regulation of vasculature development GO:1901342 88 0.031
nucleoside phosphate catabolic process GO:1901292 222 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
regulation of cellular catabolic process GO:0031329 242 0.031
regulation of alpha beta t cell activation GO:0046634 53 0.031
actin polymerization or depolymerization GO:0008154 54 0.031
nucleoside catabolic process GO:0009164 206 0.030
hemostasis GO:0007599 78 0.030
endocytosis GO:0006897 168 0.030
acute inflammatory response GO:0002526 41 0.030
negative regulation of phosphorylation GO:0042326 166 0.030
regulation of regulated secretory pathway GO:1903305 20 0.030
regulation of hormone secretion GO:0046883 88 0.030
regulation of cytokine secretion GO:0050707 61 0.030
lipid localization GO:0010876 126 0.030
regulation of cell killing GO:0031341 40 0.030
regulation of cell shape GO:0008360 39 0.030
nuclear import GO:0051170 95 0.030
regulation of fat cell differentiation GO:0045598 81 0.030
regulation of secretion by cell GO:1903530 249 0.030
regulation of anatomical structure size GO:0090066 178 0.030
eosinophil activation involved in immune response GO:0002278 1 0.029
regulation of kinase activity GO:0043549 249 0.029
neuron projection guidance GO:0097485 141 0.029
hormone secretion GO:0046879 128 0.029
positive regulation of ras gtpase activity GO:0032320 65 0.029
protein localization to organelle GO:0033365 185 0.029
positive regulation vascular endothelial growth factor production GO:0010575 10 0.029
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.029
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.029
regulation of apoptotic signaling pathway GO:2001233 197 0.029
disruption by host of symbiont cells GO:0051852 11 0.029
nucleocytoplasmic transport GO:0006913 139 0.029
positive regulation of response to wounding GO:1903036 66 0.029
antimicrobial peptide biosynthetic process GO:0002777 2 0.029
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.029
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.029
cellular response to acid chemical GO:0071229 68 0.029
gliogenesis GO:0042063 141 0.028
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.028
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.028
cerebral cortex cell migration GO:0021795 44 0.028
t cell extravasation GO:0072683 4 0.028
glycoprotein metabolic process GO:0009100 116 0.028
sensory perception GO:0007600 245 0.028
regulation of leukocyte differentiation GO:1902105 159 0.028
t cell differentiation in thymus GO:0033077 77 0.028
negative regulation of molecular function GO:0044092 258 0.028
nuclear transport GO:0051169 139 0.028
positive regulation of gtpase activity GO:0043547 85 0.028
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.028
positive regulation of secretion by cell GO:1903532 114 0.028
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.028
protein kinase b signaling GO:0043491 74 0.027
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.027
engulfment of apoptotic cell GO:0043652 3 0.027
positive regulation of cellular catabolic process GO:0031331 148 0.027
regulation of cell adhesion GO:0030155 154 0.027
positive regulation of chemokine production GO:0032722 22 0.027
release of sequestered calcium ion into cytosol GO:0051209 42 0.027
eosinophil migration GO:0072677 3 0.027
negative regulation of inflammatory response GO:0050728 61 0.027
actin filament polymerization GO:0030041 44 0.027
positive regulation of protein modification process GO:0031401 299 0.027
negative regulation of innate immune response GO:0045824 17 0.027
calcium ion transport GO:0006816 159 0.027
osteoclast differentiation GO:0030316 62 0.027
regulation of actin filament length GO:0030832 45 0.026
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.026
killing by host of symbiont cells GO:0051873 11 0.026
b cell activation GO:0042113 161 0.026
regulation of cell projection assembly GO:0060491 38 0.026
skeletal system morphogenesis GO:0048705 203 0.026
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.026
extracellular matrix organization GO:0030198 147 0.026
immunoglobulin production GO:0002377 73 0.026
regulation of t helper 1 type immune response GO:0002825 17 0.026
pallium development GO:0021543 120 0.025
cellular response to molecule of fungal origin GO:0071226 2 0.025
natural killer cell mediated immunity GO:0002228 29 0.025
myeloid leukocyte activation GO:0002274 83 0.025
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
negative regulation of defense response GO:0031348 77 0.025
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.025
cytokine production involved in immune response GO:0002367 34 0.025
negative regulation of protein phosphorylation GO:0001933 126 0.025
negative regulation of kinase activity GO:0033673 81 0.025
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.025
positive regulation of kinase activity GO:0033674 155 0.025
regulation of b cell activation GO:0050864 81 0.024
myeloid cell homeostasis GO:0002262 114 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
regulation of b cell proliferation GO:0030888 39 0.024
cell recognition GO:0008037 83 0.024
regulation of striated muscle cell differentiation GO:0051153 81 0.024
regulation of rho protein signal transduction GO:0035023 71 0.024
negative regulation of secretion GO:0051048 61 0.024
positive regulation of protein secretion GO:0050714 52 0.024
negative regulation of macrophage apoptotic process GO:2000110 3 0.024
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.024
positive regulation of nucleoside metabolic process GO:0045979 91 0.024
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.024
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.024
b cell chemotaxis GO:0035754 3 0.024
cellular response to interferon gamma GO:0071346 25 0.023
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.023
cytosolic calcium ion homeostasis GO:0051480 70 0.023
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045425 2 0.023
negative regulation of eosinophil degranulation GO:0043310 1 0.023
skeletal muscle fiber development GO:0048741 58 0.023
response to growth factor GO:0070848 198 0.023
regulation of endopeptidase activity GO:0052548 89 0.023
positive regulation of lymphocyte differentiation GO:0045621 61 0.023
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.023
cell fate commitment GO:0045165 210 0.023
protein import into nucleus GO:0006606 95 0.023
regulation of nitric oxide biosynthetic process GO:0045428 18 0.023
positive regulation of leukocyte mediated immunity GO:0002705 70 0.023
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.023
negative regulation of apoptotic signaling pathway GO:2001234 104 0.023
coagulation GO:0050817 78 0.023
dorsal ventral axon guidance GO:0033563 3 0.023
regulation of intracellular transport GO:0032386 159 0.022
positive regulation of protein transport GO:0051222 93 0.022
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.022
regulation of myotube differentiation GO:0010830 62 0.022
regulation of nucleocytoplasmic transport GO:0046822 73 0.022
positive regulation of muscle cell differentiation GO:0051149 39 0.022
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.022
regulation of proteolysis GO:0030162 164 0.022
intrinsic apoptotic signaling pathway GO:0097193 132 0.022
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.022
positive regulation of thymocyte migration GO:2000412 2 0.022
t cell migration GO:0072678 19 0.022
t helper 2 cell cytokine production GO:0035745 4 0.022
tumor necrosis factor production GO:0032640 50 0.022
branching morphogenesis of an epithelial tube GO:0048754 159 0.022
regulation of macrophage chemotaxis GO:0010758 8 0.022
chemokine production GO:0032602 34 0.021
morphogenesis of a branching epithelium GO:0061138 193 0.021

Slfn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.038
cancer DOID:162 0 0.025