Mus musculus

10 known processes

Aldh6a1

aldehyde dehydrogenase family 6, subfamily A1

(Aliases: 1110038I05Rik,MGC37325,Mmsdh,AI314632)

Aldh6a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
steroid metabolic process GO:0008202 119 0.390
sterol metabolic process GO:0016125 58 0.286
small molecule biosynthetic process GO:0044283 132 0.278
fatty acid metabolic process GO:0006631 121 0.244
organic hydroxy compound metabolic process GO:1901615 203 0.241
cellular lipid metabolic process GO:0044255 323 0.202
lipid biosynthetic process GO:0008610 179 0.198
alcohol metabolic process GO:0006066 116 0.175
cofactor metabolic process GO:0051186 80 0.167
cellular amino acid metabolic process GO:0006520 103 0.160
Human Rat
thioester metabolic process GO:0035383 19 0.149
cellular ketone metabolic process GO:0042180 84 0.127
organic hydroxy compound biosynthetic process GO:1901617 77 0.117
coenzyme metabolic process GO:0006732 52 0.112
organic acid catabolic process GO:0016054 51 0.110
Human Rat
protein catabolic process GO:0030163 221 0.101
c21 steroid hormone biosynthetic process GO:0006700 3 0.099
monocarboxylic acid biosynthetic process GO:0072330 61 0.093
organic acid biosynthetic process GO:0016053 86 0.092
glycerolipid metabolic process GO:0046486 122 0.084
regulation of cellular ketone metabolic process GO:0010565 66 0.084
amine metabolic process GO:0009308 45 0.080
macromolecule catabolic process GO:0009057 281 0.077
cellular amine metabolic process GO:0044106 44 0.076
generation of precursor metabolites and energy GO:0006091 103 0.069
organophosphate biosynthetic process GO:0090407 122 0.064
regulation of steroid biosynthetic process GO:0050810 26 0.062
small molecule catabolic process GO:0044282 71 0.061
Human Rat
carboxylic acid biosynthetic process GO:0046394 86 0.061
peroxisome organization GO:0007031 7 0.061
alcohol biosynthetic process GO:0046165 43 0.060
medium chain fatty acid metabolic process GO:0051791 1 0.057
cholesterol metabolic process GO:0008203 56 0.055
cellular amino acid catabolic process GO:0009063 25 0.055
Human Rat
nucleoside phosphate metabolic process GO:0006753 338 0.054
modification dependent macromolecule catabolic process GO:0043632 133 0.052
nucleotide metabolic process GO:0009117 332 0.050
coenzyme biosynthetic process GO:0009108 23 0.048
response to inorganic substance GO:0010035 96 0.048
ossification GO:0001503 216 0.047
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.047
response to oxidative stress GO:0006979 123 0.047
steroid biosynthetic process GO:0006694 47 0.046
nucleobase containing small molecule metabolic process GO:0055086 352 0.044
Human Rat
cellular macromolecule catabolic process GO:0044265 206 0.043
regulation of ossification GO:0030278 112 0.043
cellular modified amino acid metabolic process GO:0006575 63 0.043
selenium compound metabolic process GO:0001887 3 0.041
cellular protein catabolic process GO:0044257 155 0.041
fatty acid oxidation GO:0019395 28 0.041
lipid catabolic process GO:0016042 69 0.040
cellular alcohol metabolic process GO:0044107 3 0.039
regulation of cellular catabolic process GO:0031329 242 0.038
response to organonitrogen compound GO:0010243 246 0.037
reactive oxygen species metabolic process GO:0072593 84 0.037
progesterone biosynthetic process GO:0006701 1 0.035
acylglycerol metabolic process GO:0006639 55 0.034
response to copper ion GO:0046688 3 0.034
response to nutrient levels GO:0031667 109 0.034
protein modification by small protein conjugation GO:0032446 187 0.034
monocarboxylic acid catabolic process GO:0072329 27 0.034
monocarboxylic acid metabolic process GO:0032787 191 0.033
modification dependent protein catabolic process GO:0019941 133 0.032
regulation of steroid metabolic process GO:0019218 39 0.032
regulation of lipid metabolic process GO:0019216 118 0.032
response to light stimulus GO:0009416 135 0.032
hepaticobiliary system development GO:0061008 67 0.031
carbohydrate derivative biosynthetic process GO:1901137 183 0.031
organic anion transport GO:0015711 137 0.030
hexose biosynthetic process GO:0019319 39 0.030
fatty acid alpha oxidation GO:0001561 2 0.030
ubiquitin dependent protein catabolic process GO:0006511 129 0.030
energy reserve metabolic process GO:0006112 39 0.029
fatty acid biosynthetic process GO:0006633 41 0.029
sulfur compound metabolic process GO:0006790 100 0.029
response to metal ion GO:0010038 47 0.029
energy derivation by oxidation of organic compounds GO:0015980 77 0.029
acetate metabolic process GO:0006083 1 0.029
neuron projection guidance GO:0097485 141 0.028
carbohydrate metabolic process GO:0005975 230 0.028
axon guidance GO:0007411 141 0.028
lipid transport GO:0006869 98 0.028
axonogenesis GO:0007409 274 0.028
cellular response to hormone stimulus GO:0032870 150 0.027
liver development GO:0001889 66 0.027
response to extracellular stimulus GO:0009991 127 0.027
neutral lipid metabolic process GO:0006638 57 0.027
gland development GO:0048732 330 0.026
ribonucleotide metabolic process GO:0009259 291 0.026
protein oligomerization GO:0051259 67 0.025
protein homooligomerization GO:0051260 43 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
cellular biogenic amine metabolic process GO:0006576 28 0.024
regulation of proteasomal protein catabolic process GO:0061136 46 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
Human Rat
chemotaxis GO:0006935 247 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
ras protein signal transduction GO:0007265 77 0.023
membrane organization GO:0061024 245 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
heterocycle catabolic process GO:0046700 280 0.023
Human Rat
nucleoside phosphate biosynthetic process GO:1901293 79 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
organonitrogen compound biosynthetic process GO:1901566 192 0.022
cellular carbohydrate metabolic process GO:0044262 119 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
acyl coa metabolic process GO:0006637 19 0.022
response to organic cyclic compound GO:0014070 198 0.022
myeloid cell differentiation GO:0030099 233 0.022
nucleocytoplasmic transport GO:0006913 139 0.021
peptidyl amino acid modification GO:0018193 336 0.021
retina development in camera type eye GO:0060041 119 0.021
glycerophospholipid metabolic process GO:0006650 71 0.021
nucleotide biosynthetic process GO:0009165 78 0.021
aromatic compound catabolic process GO:0019439 286 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.020
regulation of fat cell differentiation GO:0045598 81 0.020
triglyceride metabolic process GO:0006641 51 0.020
response to starvation GO:0042594 65 0.020
glycogen biosynthetic process GO:0005978 14 0.020
regulation of cellular amino acid metabolic process GO:0006521 5 0.020
cellular response to growth factor stimulus GO:0071363 197 0.020
phosphatidylethanolamine metabolic process GO:0046337 2 0.020
rna processing GO:0006396 105 0.020
lipid localization GO:0010876 126 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
ribonucleoside bisphosphate metabolic process GO:0033875 9 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
amino acid betaine metabolic process GO:0006577 7 0.019
cellular alcohol biosynthetic process GO:0044108 3 0.019
mapk cascade GO:0000165 281 0.019
pyridine nucleotide catabolic process GO:0019364 3 0.019
polysaccharide metabolic process GO:0005976 39 0.019
protein ubiquitination GO:0016567 171 0.019
regulation of lipid biosynthetic process GO:0046890 54 0.019
lipoprotein metabolic process GO:0042157 43 0.019
urogenital system development GO:0001655 261 0.018
alpha amino acid metabolic process GO:1901605 59 0.018
Human Rat
regulation of ketone biosynthetic process GO:0010566 2 0.018
positive regulation of lipid biosynthetic process GO:0046889 18 0.018
positive regulation of steroid biosynthetic process GO:0010893 4 0.018
male meiosis i GO:0007141 16 0.018
anion transport GO:0006820 177 0.018
positive regulation of protein modification process GO:0031401 299 0.018
regulation of membrane potential GO:0042391 192 0.018
nuclear division GO:0000280 158 0.018
negative regulation of fatty acid metabolic process GO:0045922 10 0.018
very long chain fatty acid catabolic process GO:0042760 2 0.018
organic hydroxy compound catabolic process GO:1901616 25 0.018
hormone metabolic process GO:0042445 86 0.018
regulation of fatty acid metabolic process GO:0019217 28 0.018
cell type specific apoptotic process GO:0097285 268 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.018
unsaturated fatty acid metabolic process GO:0033559 31 0.018
small gtpase mediated signal transduction GO:0007264 97 0.017
fatty acid beta oxidation GO:0006635 16 0.017
paracrine signaling GO:0038001 1 0.017
oxidation reduction process GO:0055114 342 0.017
Human Rat
sensory perception GO:0007600 245 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
protein tetramerization GO:0051262 23 0.017
chromatin modification GO:0016568 187 0.017
maintenance of location GO:0051235 89 0.017
renal system development GO:0072001 225 0.017
regulation of homeostatic process GO:0032844 182 0.017
regulation of protein catabolic process GO:0042176 108 0.017
multicellular organismal signaling GO:0035637 91 0.017
myeloid leukocyte differentiation GO:0002573 119 0.017
regulation of organelle organization GO:0033043 289 0.017
glycosyl compound metabolic process GO:1901657 246 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
icosanoid metabolic process GO:0006690 33 0.016
positive regulation of cell death GO:0010942 224 0.016
regulation of cellular response to growth factor stimulus GO:0090287 82 0.016
phospholipid metabolic process GO:0006644 87 0.016
organophosphate ester transport GO:0015748 28 0.016
response to growth factor GO:0070848 198 0.016
response to radiation GO:0009314 165 0.016
very long chain fatty acid metabolic process GO:0000038 8 0.016
substantia nigra development GO:0021762 2 0.016
regulation of myeloid leukocyte differentiation GO:0002761 58 0.016
prostaglandin metabolic process GO:0006693 11 0.016
telencephalon development GO:0021537 186 0.016
fatty acid derivative metabolic process GO:1901568 33 0.016
skeletal muscle cell differentiation GO:0035914 66 0.015
nucleoside metabolic process GO:0009116 246 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
gonad development GO:0008406 141 0.015
muscle cell differentiation GO:0042692 261 0.015
glycerophospholipid biosynthetic process GO:0046474 32 0.015
sterol transport GO:0015918 38 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
fat cell differentiation GO:0045444 160 0.015
negative regulation of immune system process GO:0002683 209 0.015
alcohol catabolic process GO:0046164 16 0.014
glucocorticoid mediated signaling pathway GO:0043402 3 0.014
intracellular protein transport GO:0006886 204 0.014
mitotic cell cycle process GO:1903047 159 0.014
connective tissue development GO:0061448 179 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
chromatin organization GO:0006325 206 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
regulation of gluconeogenesis GO:0006111 30 0.014
carbohydrate biosynthetic process GO:0016051 74 0.014
transmembrane transport GO:0055085 412 0.014
kidney development GO:0001822 213 0.014
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 3 0.014
sensory organ morphogenesis GO:0090596 242 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
cellular response to oxidative stress GO:0034599 76 0.014
striated muscle tissue development GO:0014706 293 0.014
ribonucleoside metabolic process GO:0009119 245 0.013
protein localization to plasma membrane GO:0072659 57 0.013
protein localization to membrane GO:0072657 108 0.013
response to acid chemical GO:0001101 111 0.013
regulation of cellular protein catabolic process GO:1903362 61 0.013
glucan metabolic process GO:0044042 32 0.013
positive regulation of dopamine secretion GO:0033603 2 0.013
nitrogen compound transport GO:0071705 271 0.013
organic hydroxy compound transport GO:0015850 93 0.013
regulation of myeloid cell differentiation GO:0045637 96 0.013
forebrain development GO:0030900 302 0.013
leukocyte apoptotic process GO:0071887 71 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
action potential GO:0001508 78 0.013
purine nucleotide biosynthetic process GO:0006164 65 0.013
positive regulation of rho gtpase activity GO:0032321 41 0.013
regulation of secretion by cell GO:1903530 249 0.013
cellular response to nutrient levels GO:0031669 64 0.012
positive regulation of lipid metabolic process GO:0045834 40 0.012
rna splicing GO:0008380 54 0.012
carboxylic acid catabolic process GO:0046395 51 0.012
Human Rat
regulation of t cell proliferation GO:0042129 92 0.012
leukocyte differentiation GO:0002521 342 0.012
purine containing compound metabolic process GO:0072521 311 0.012
tissue homeostasis GO:0001894 115 0.012
cytoplasmic transport GO:0016482 234 0.012
positive regulation of catecholamine secretion GO:0033605 2 0.012
heart morphogenesis GO:0003007 178 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
alpha amino acid catabolic process GO:1901606 18 0.012
Human Rat
dna metabolic process GO:0006259 303 0.012
positive regulation of steroid metabolic process GO:0045940 5 0.012
response to amino acid GO:0043200 37 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
compound eye development GO:0048749 1 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
hexose metabolic process GO:0019318 98 0.012
skeletal system development GO:0001501 356 0.012
icosanoid biosynthetic process GO:0046456 15 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
transmission of nerve impulse GO:0019226 76 0.012
naphthalene containing compound metabolic process GO:0090420 1 0.012
nuclear transport GO:0051169 139 0.012
regulation of hormone levels GO:0010817 211 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
Human Rat
multicellular organism growth GO:0035264 161 0.012
organophosphate catabolic process GO:0046434 232 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
lung development GO:0030324 164 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
regulation of cell activation GO:0050865 289 0.011
bone development GO:0060348 120 0.011
homeostasis of number of cells GO:0048872 210 0.011
regulation of t cell activation GO:0050863 170 0.011
response to reactive oxygen species GO:0000302 56 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
protein localization to peroxisome GO:0072662 4 0.011
pyruvate transport GO:0006848 2 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
male gamete generation GO:0048232 285 0.011
regulation of cellular response to stress GO:0080135 159 0.011
erk1 and erk2 cascade GO:0070371 77 0.011
cytokine production GO:0001816 319 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
regulation of proteolysis GO:0030162 164 0.011
ear development GO:0043583 200 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
bone morphogenesis GO:0060349 78 0.011
negative regulation of ossification GO:0030279 49 0.011
regulation of glucose metabolic process GO:0010906 60 0.011
camera type eye development GO:0043010 266 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
positive regulation of glycolytic process GO:0045821 4 0.011
regulation of mapk cascade GO:0043408 248 0.011
regulation of intracellular transport GO:0032386 159 0.010
cellular response to topologically incorrect protein GO:0035967 25 0.010
skeletal system morphogenesis GO:0048705 203 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.010
male sex differentiation GO:0046661 109 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
regulation of cytokine production GO:0001817 266 0.010
meiotic nuclear division GO:0007126 115 0.010
glycoprotein metabolic process GO:0009100 116 0.010
regulation of mitochondrial fission GO:0090140 3 0.010
intracellular sterol transport GO:0032366 3 0.010
nucleoside phosphate catabolic process GO:1901292 222 0.010
lymphocyte apoptotic process GO:0070227 54 0.010
regulation of osteoblast differentiation GO:0045667 67 0.010
neuron death GO:0070997 154 0.010
cell maturation GO:0048469 127 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
cellular nitrogen compound catabolic process GO:0044270 280 0.010
Human Rat
regulation of leukocyte proliferation GO:0070663 121 0.010
actin cytoskeleton organization GO:0030036 220 0.010
cellular response to acid chemical GO:0071229 68 0.010
adiponectin activated signaling pathway GO:0033211 4 0.010

Aldh6a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.819
amino acid metabolic disorder DOID:9252 0 0.551
inherited metabolic disorder DOID:655 0 0.551
organic acidemia DOID:0060159 0 0.370
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.042
sensory system disease DOID:0050155 0 0.030
eye and adnexa disease DOID:1492 0 0.030
retinal disease DOID:5679 0 0.026
retinal degeneration DOID:8466 0 0.026
retinitis pigmentosa DOID:10584 0 0.026
eye disease DOID:5614 0 0.026