Mus musculus

151 known processes

Slit2

slit homolog 2 (Drosophila)

(Aliases: Drad-1,E130320P19Rik,E030015M03Rik,KIAA4141,mKIAA4141,Slil3)

Slit2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dorsal ventral axon guidance GO:0033563 3 1.000
roundabout signaling pathway GO:0035385 0 0.999
Human Fly
negative regulation of axon guidance GO:1902668 8 0.996
Human Worm
central nervous system projection neuron axonogenesis GO:0021952 21 0.991
Human Zebrafish
negative chemotaxis GO:0050919 14 0.986
cell cell adhesion GO:0098609 41 0.984
central nervous system neuron axonogenesis GO:0021955 28 0.978
Human Zebrafish
regulation of negative chemotaxis GO:0050923 1 0.977
Human Fly
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.977
cardiac cell fate specification GO:0060912 2 0.974
formation of organ boundary GO:0010160 1 0.973
Fly
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.965
negative regulation of chemotaxis GO:0050922 11 0.931
Human Rat Worm
motor neuron axon guidance GO:0008045 26 0.925
Human
negative regulation of behavior GO:0048521 14 0.924
Human Rat Worm
single organismal cell cell adhesion GO:0016337 131 0.885
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.879
Human
negative regulation of axon extension GO:0030517 19 0.878
retinal ganglion cell axon guidance GO:0031290 18 0.868
axon guidance GO:0007411 141 0.863
urogenital system development GO:0001655 261 0.855
negative regulation of synapse assembly GO:0051964 3 0.852
regulation of axon guidance GO:1902667 13 0.851
Human Worm
epithelial tube morphogenesis GO:0060562 303 0.846
commissural neuron axon guidance GO:0071679 8 0.828
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.823
Human Worm
anterior posterior axon guidance GO:0033564 5 0.819
Zebrafish
olfactory bulb interneuron differentiation GO:0021889 12 0.812
Human
neuron migration GO:0001764 122 0.807
Worm Fly
chemokine mediated signaling pathway GO:0070098 17 0.806
Human
kidney development GO:0001822 213 0.799
regulation of axon extension GO:0030516 43 0.792
glial cell migration GO:0008347 7 0.779
Fly
central nervous system neuron development GO:0021954 67 0.776
Human Zebrafish
developmental growth involved in morphogenesis GO:0060560 138 0.742
mammary gland morphogenesis GO:0060443 54 0.740
mammary gland duct morphogenesis GO:0060603 38 0.738
regulation of cellular component size GO:0032535 121 0.735
forebrain development GO:0030900 302 0.728
negative regulation of cell projection organization GO:0031345 56 0.714
negative regulation of neuron projection development GO:0010977 50 0.709
neuron recognition GO:0008038 25 0.709
Zebrafish Fly
neuron projection extension GO:1990138 64 0.702
telencephalon development GO:0021537 186 0.700
skeletal system development GO:0001501 356 0.693
Mouse
renal system development GO:0072001 225 0.688
mammary gland epithelium development GO:0061180 65 0.685
forebrain neuron development GO:0021884 30 0.669
Human
cell recognition GO:0008037 83 0.666
Zebrafish Fly
substrate dependent cell migration GO:0006929 18 0.655
Human
negative regulation of leukocyte differentiation GO:1902106 51 0.651
Mouse
negative regulation of cell development GO:0010721 169 0.650
cell adhesion GO:0007155 329 0.649
positive regulation of cell adhesion GO:0045785 80 0.637
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.618
regulation of cell adhesion GO:0030155 154 0.615
Fly
chemotaxis GO:0006935 247 0.603
axonogenesis GO:0007409 274 0.602
axon extension involved in axon guidance GO:0048846 14 0.599
Human Worm
regulation of neuron projection development GO:0010975 169 0.585
regionalization GO:0003002 337 0.568
Fly
positive regulation of cell development GO:0010720 237 0.567
metanephros development GO:0001656 79 0.565
single organism cell adhesion GO:0098602 156 0.562
mammary duct terminal end bud growth GO:0060763 5 0.561
positive regulation of neuron differentiation GO:0045666 141 0.549
negative regulation of myeloid cell differentiation GO:0045638 38 0.544
Mouse
developmental cell growth GO:0048588 84 0.538
dendrite development GO:0016358 115 0.536
Fly
gastrulation GO:0007369 116 0.533
Fly
formation of anatomical boundary GO:0048859 6 0.528
Fly
olfactory lobe development GO:0021988 32 0.523
gliogenesis GO:0042063 141 0.520
Fly
regulation of cell size GO:0008361 72 0.517
rhythmic process GO:0048511 174 0.513
Human
kidney epithelium development GO:0072073 121 0.497
Human
salivary gland development GO:0007431 37 0.495
Fly
neuron projection guidance GO:0097485 141 0.490
forebrain cell migration GO:0021885 58 0.469
cerebral cortex development GO:0021987 86 0.461
Human
olfactory bulb development GO:0021772 30 0.459
gland development GO:0048732 330 0.454
cell fate commitment GO:0045165 210 0.452
Fly
regulation of cell projection organization GO:0031344 206 0.434
regulation of neuron differentiation GO:0045664 281 0.433
cytokine mediated signaling pathway GO:0019221 115 0.431
Human
heart morphogenesis GO:0003007 178 0.430
Zebrafish Fly
nucleus localization GO:0051647 20 0.427
Mouse
development of primary sexual characteristics GO:0045137 143 0.422
Human Fly
axonal fasciculation GO:0007413 15 0.414
regulation of anatomical structure size GO:0090066 178 0.413
regulation of cell growth GO:0001558 91 0.398
forebrain generation of neurons GO:0021872 63 0.397
Human
negative regulation of nervous system development GO:0051961 156 0.392
cell growth GO:0016049 130 0.392
cerebral cortex tangential migration GO:0021800 7 0.369
Human
positive regulation of cell projection organization GO:0031346 95 0.358
positive regulation of chemotaxis GO:0050921 38 0.350
Human Fly
regulation of myeloid leukocyte differentiation GO:0002761 58 0.348
Mouse
spinal cord development GO:0021510 81 0.348
Rat
mesonephros development GO:0001823 97 0.347
Human
blood vessel endothelial cell migration GO:0043534 23 0.343
Human
mesodermal cell migration GO:0008078 4 0.330
Fly
cell migration involved in gastrulation GO:0042074 13 0.330
Fly
negative regulation of cell growth GO:0030308 44 0.323
osteoclast differentiation GO:0030316 62 0.318
Mouse
telencephalon cell migration GO:0022029 55 0.316
female gonad development GO:0008585 71 0.315
Human
negative regulation of cell proliferation GO:0008285 296 0.314
regulation of extent of cell growth GO:0061387 52 0.311
regulation of circadian rhythm GO:0042752 58 0.305
digestive tract morphogenesis GO:0048546 147 0.305
Fly
regulation of chemotaxis GO:0050920 53 0.305
Human Rat Worm Fly
positive regulation of neuron projection development GO:0010976 79 0.303
stem cell differentiation GO:0048863 268 0.287
cell migration involved in heart formation GO:0060974 1 0.285
Zebrafish
regulation of leukocyte differentiation GO:1902105 159 0.279
Mouse
ovulation cycle GO:0042698 59 0.275
Human
negative regulation of growth GO:0045926 99 0.274
lateral inhibition GO:0046331 1 0.270
Fly
olfactory bulb interneuron development GO:0021891 7 0.268
Human
ureteric bud development GO:0001657 94 0.262
Human
regulation of cellular component biogenesis GO:0044087 181 0.260
Human
cerebral cortex cell migration GO:0021795 44 0.256
Human
negative regulation of neuron differentiation GO:0045665 101 0.254
positive regulation of nervous system development GO:0051962 221 0.254
pallium development GO:0021543 120 0.253
Human
cardioblast migration GO:0003260 1 0.248
Zebrafish
forebrain neuron differentiation GO:0021879 52 0.246
Human
gonad development GO:0008406 141 0.245
Human Fly
tissue migration GO:0090130 68 0.241
Human Fly
positive regulation of axon extension GO:0045773 20 0.239
epithelial cell migration GO:0010631 63 0.238
Human Fly
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.236
Zebrafish
positive regulation of behavior GO:0048520 40 0.225
Human Fly
mesoderm development GO:0007498 100 0.225
Fly
central nervous system neuron differentiation GO:0021953 162 0.223
Human Zebrafish
amine metabolic process GO:0009308 45 0.215
regulation of cell migration GO:0030334 219 0.209
Human Rat Fly
locomotory behavior GO:0007626 195 0.209
exocrine system development GO:0035272 45 0.207
Fly
regulation of myeloid cell differentiation GO:0045637 96 0.207
Mouse
establishment of organelle localization GO:0051656 122 0.203
Mouse
epithelium migration GO:0090132 63 0.203
Human Fly
mesonephric epithelium development GO:0072163 94 0.199
Human
synapse assembly GO:0007416 56 0.196
digestive tract development GO:0048565 190 0.195
Fly
female sex differentiation GO:0046660 84 0.190
Human
outflow tract morphogenesis GO:0003151 53 0.186
Fly
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.186
bone marrow development GO:0048539 3 0.185
Mouse
negative regulation of mammary gland epithelial cell proliferation GO:0033600 3 0.181
regulation of cell motility GO:2000145 236 0.180
Human Rat Fly
bone development GO:0060348 120 0.175
Mouse
negative regulation of immune system process GO:0002683 209 0.175
Human Mouse Rat
neuromuscular process GO:0050905 99 0.173
cell fate specification GO:0001708 72 0.170
regulation of osteoclast differentiation GO:0045670 36 0.168
Mouse
cardioblast differentiation GO:0010002 13 0.155
regulation of cellular amino acid metabolic process GO:0006521 5 0.150
regulation of cellular amine metabolic process GO:0033238 20 0.146
myeloid cell differentiation GO:0030099 233 0.146
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.145
Mouse
mesoderm formation GO:0001707 62 0.145
Fly
mesoderm morphogenesis GO:0048332 64 0.136
Fly
protein processing GO:0016485 163 0.134
locomotion involved in locomotory behavior GO:0031987 8 0.131
cellular amino acid metabolic process GO:0006520 103 0.130
cardiocyte differentiation GO:0035051 87 0.130
digestive system development GO:0055123 200 0.129
Fly
negative regulation of cell migration GO:0030336 59 0.128
Human Rat
embryonic heart tube development GO:0035050 65 0.126
Fly
cellular response to hormone stimulus GO:0032870 150 0.124
Human
cell migration to the midline involved in heart development GO:0003318 1 0.124
Zebrafish
mesonephric tubule development GO:0072164 94 0.123
Human
negative regulation of cellular component organization GO:0051129 194 0.122
trunk neural crest cell migration GO:0036484 4 0.118
mammary gland epithelial cell proliferation GO:0033598 24 0.117
cellular homeostasis GO:0019725 240 0.116
ear development GO:0043583 200 0.108
regulation of hydrolase activity GO:0051336 246 0.106
positive chemotaxis GO:0050918 18 0.100
ameboidal type cell migration GO:0001667 128 0.098
Human Fly
angiogenesis GO:0001525 201 0.097
Human
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.096
development of primary female sexual characteristics GO:0046545 73 0.094
Human
branching morphogenesis of an epithelial tube GO:0048754 159 0.094
Human
positive regulation of proteolysis GO:0045862 85 0.089
negative regulation of cell motility GO:2000146 61 0.087
Human Rat
protein maturation GO:0051604 176 0.086
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.082
sensory organ morphogenesis GO:0090596 242 0.078
regulation of epithelial cell proliferation GO:0050678 141 0.078
brain morphogenesis GO:0048854 32 0.077
positive regulation of cellular amine metabolic process GO:0033240 5 0.077
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.074
circadian rhythm GO:0007623 114 0.070
nitrogen compound transport GO:0071705 271 0.070
striated muscle tissue development GO:0014706 293 0.070
sympathetic neuron projection guidance GO:0097491 4 0.069
regulation of proteolysis GO:0030162 164 0.068
sympathetic neuron projection extension GO:0097490 4 0.068
muscle cell cellular homeostasis GO:0046716 12 0.066
membrane organization GO:0061024 245 0.063
negative regulation of response to cytokine stimulus GO:0060761 9 0.061
Human
mesenchyme development GO:0060485 152 0.060
apoptotic process involved in development GO:1902742 28 0.059
Human
cell migration involved in sprouting angiogenesis GO:0002042 9 0.059
Human
fasciculation of motor neuron axon GO:0097156 2 0.058
ossification GO:0001503 216 0.058
regulation of mapk cascade GO:0043408 248 0.058
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.058
Mouse
peptide hormone secretion GO:0030072 109 0.058
cellular ketone metabolic process GO:0042180 84 0.058
bmp signaling pathway GO:0030509 93 0.057
fasciculation of sensory neuron axon GO:0097155 3 0.056
cellular amine metabolic process GO:0044106 44 0.055
regulation of actin filament based process GO:0032970 99 0.055
Human
blood vessel morphogenesis GO:0048514 285 0.053
Human
regulation of cellular ketone metabolic process GO:0010565 66 0.053
ventral trunk neural crest cell migration GO:0036486 4 0.052
anatomical structure homeostasis GO:0060249 145 0.052
negative regulation of ovulation GO:0060280 1 0.051
nephron development GO:0072006 109 0.050
neuron apoptotic process GO:0051402 142 0.050
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.049
regulation of endopeptidase activity GO:0052548 89 0.048
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.048
multicellular organismal signaling GO:0035637 91 0.047
regulation of map kinase activity GO:0043405 120 0.047
regulation of cytoskeleton organization GO:0051493 122 0.046
Human
negative regulation of epithelial cell proliferation GO:0050680 64 0.045
engulfment of apoptotic cell GO:0043652 3 0.045
extracellular structure organization GO:0043062 148 0.045
ensheathment of neurons GO:0007272 76 0.045
transmission of nerve impulse GO:0019226 76 0.045
renal tubule development GO:0061326 87 0.044
leukocyte differentiation GO:0002521 342 0.044
Mouse
appendage development GO:0048736 166 0.044
action potential GO:0001508 78 0.043
organelle localization GO:0051640 179 0.043
Mouse
response to steroid hormone GO:0048545 56 0.043
Human
rhodopsin mediated signaling pathway GO:0016056 4 0.042
cellular component assembly involved in morphogenesis GO:0010927 139 0.040
regulation of hormone levels GO:0010817 211 0.040
morphogenesis of a branching epithelium GO:0061138 193 0.040
Human
kidney morphogenesis GO:0060993 83 0.039
glial cell differentiation GO:0010001 131 0.039
cation homeostasis GO:0055080 212 0.039
hypothalamic tangential migration using cell axon interactions GO:0021856 3 0.038
corpus callosum development GO:0022038 10 0.038
rac protein signal transduction GO:0016601 13 0.038
compound eye development GO:0048749 1 0.037
regulation of actin filament polymerization GO:0030833 38 0.037
Human
neuron death GO:0070997 154 0.037
neural precursor cell proliferation GO:0061351 121 0.036
cellular chemical homeostasis GO:0055082 215 0.036
negative regulation of osteoclast differentiation GO:0045671 12 0.036
Mouse
immune effector process GO:0002252 321 0.036
vegf activated neuropilin signaling pathway involved in axon guidance GO:1902378 1 0.036
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.036
positive regulation of growth GO:0045927 104 0.035
actin filament polymerization GO:0030041 44 0.035
Human
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.035
limbic system development GO:0021761 72 0.035
regulation of organelle organization GO:0033043 289 0.035
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.034
regulation of epithelial cell migration GO:0010632 35 0.033
Human Fly
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.033
regulation of neuron projection regeneration GO:0070570 7 0.033
cation transmembrane transport GO:0098655 266 0.033
respiratory tube development GO:0030323 167 0.033
neural tube development GO:0021915 160 0.033
regulation of actin cytoskeleton organization GO:0032956 84 0.033
Human
camera type eye development GO:0043010 266 0.033
negative regulation of neuron projection regeneration GO:0070571 3 0.032
positive regulation of mapk cascade GO:0043410 170 0.032
oligodendrocyte differentiation GO:0048709 53 0.032
microtubule cytoskeleton organization GO:0000226 157 0.032
facioacoustic ganglion development GO:1903375 3 0.031
response to alcohol GO:0097305 48 0.031
Human
nucleotide metabolic process GO:0009117 332 0.031
Human
apoptotic signaling pathway GO:0097190 306 0.031
regulation of peptide hormone secretion GO:0090276 75 0.031
cell chemotaxis GO:0060326 81 0.030
Human Rat
positive regulation of protein modification process GO:0031401 299 0.030
peptidyl tyrosine phosphorylation GO:0018108 143 0.030
heart formation GO:0060914 16 0.030
Zebrafish
hormone secretion GO:0046879 128 0.030
oocyte axis specification GO:0007309 2 0.030
autonomic nervous system development GO:0048483 43 0.029
cardiac cell fate commitment GO:0060911 10 0.029
defecation GO:0030421 1 0.029
endocytosis GO:0006897 168 0.029
hypothalamus gonadotrophin releasing hormone neuron differentiation GO:0021886 4 0.029
regulation of peptidase activity GO:0052547 96 0.028
regulation of actin nucleation GO:0051125 4 0.028
cellular glucose homeostasis GO:0001678 52 0.028
regulation of vesicle mediated transport GO:0060627 139 0.028
formation of primary germ layer GO:0001704 77 0.028
Fly
positive regulation of cellular component biogenesis GO:0044089 94 0.028
cation transport GO:0006812 399 0.028
epithelial cell proliferation GO:0050673 174 0.028
mesonephric tubule morphogenesis GO:0072171 63 0.028
regulation of peptide secretion GO:0002791 77 0.028
regulation of system process GO:0044057 200 0.027
axon ensheathment GO:0008366 76 0.027
positive regulation of cell growth GO:0030307 33 0.027
negative regulation of molecular function GO:0044092 258 0.027
Human
neuronal action potential GO:0019228 54 0.027
positive regulation of map kinase activity GO:0043406 84 0.026
mapk cascade GO:0000165 281 0.026
regulation of cell shape GO:0008360 39 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
Human
trunk segmentation GO:0035290 4 0.026
activation of cysteine type endopeptidase activity GO:0097202 27 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
Human
regulation of neuron death GO:1901214 134 0.026
vesicle organization GO:0016050 60 0.025
palate development GO:0060021 76 0.025
labyrinthine layer development GO:0060711 49 0.025
regulation of cysteine type endopeptidase activity GO:2000116 65 0.025
g protein coupled receptor signaling pathway GO:0007186 243 0.025
branchiomotor neuron axon guidance GO:0021785 7 0.025
terminal button organization GO:0072553 3 0.025
cellular lipid metabolic process GO:0044255 323 0.024
regulation of homeostatic process GO:0032844 182 0.024
developmental maturation GO:0021700 193 0.024
amide transport GO:0042886 138 0.024
regulation of cell substrate adhesion GO:0010810 73 0.024
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 5 0.024
Human Mouse
ear morphogenesis GO:0042471 118 0.024
asymmetric stem cell division GO:0098722 3 0.024
spinal cord ventral commissure morphogenesis GO:0021965 2 0.024
muscle cell differentiation GO:0042692 261 0.023
actin cytoskeleton organization GO:0030036 220 0.023
Human
synapse organization GO:0050808 125 0.023
regulation of protein kinase activity GO:0045859 232 0.023
stem cell development GO:0048864 219 0.023
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.023
semaphorin plexin signaling pathway involved in neuron projection guidance GO:1902285 6 0.023
lateral line system development GO:0048925 1 0.023
regulation of apoptotic signaling pathway GO:2001233 197 0.022
synaptic transmission GO:0007268 329 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.022
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.022
regulation of peptide transport GO:0090087 91 0.022
cellular protein complex assembly GO:0043623 116 0.022
Human
actin filament organization GO:0007015 113 0.022
Human
lipid biosynthetic process GO:0008610 179 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
Human
positive regulation of protein phosphorylation GO:0001934 242 0.021
microtubule based process GO:0007017 236 0.021
cell maturation GO:0048469 127 0.021
lung development GO:0030324 164 0.021
regulation of bmp signaling pathway GO:0030510 60 0.021
peptide transport GO:0015833 133 0.021
glucose homeostasis GO:0042593 128 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
Human
axon regeneration GO:0031103 12 0.021
lymphocyte differentiation GO:0030098 242 0.021
nephron epithelium development GO:0072009 92 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
Human
homotypic cell cell adhesion GO:0034109 28 0.021
regulation of hormone secretion GO:0046883 88 0.021
regulation of response to cytokine stimulus GO:0060759 23 0.021
Human
endomembrane system organization GO:0010256 147 0.021
ribonucleotide metabolic process GO:0009259 291 0.020
Human
intracellular protein transport GO:0006886 204 0.020
negative regulation of hormone metabolic process GO:0032351 4 0.020
cilium assembly GO:0042384 81 0.020
embryonic organ morphogenesis GO:0048562 276 0.020
sensory perception GO:0007600 245 0.020
myelination GO:0042552 74 0.020
regulation of response to wounding GO:1903034 189 0.020
Rat
negative regulation of apoptotic signaling pathway GO:2001234 104 0.020
maintenance of location GO:0051235 89 0.020
cellular response to lipid GO:0071396 145 0.020
positive regulation of protein kinase activity GO:0045860 144 0.019
peptidyl tyrosine modification GO:0018212 145 0.019
positive regulation of transferase activity GO:0051347 167 0.019
cellular component maintenance GO:0043954 11 0.019
regulation of membrane potential GO:0042391 192 0.019
sensory neuron axon guidance GO:0097374 3 0.019
regulation of terminal button organization GO:2000331 1 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
Human
muscle tissue development GO:0060537 308 0.019
leukocyte activation involved in immune response GO:0002366 126 0.019
regulation of actin filament length GO:0030832 45 0.019
Human
cellular carbohydrate metabolic process GO:0044262 119 0.019
axial mesoderm formation GO:0048320 3 0.019
female gamete generation GO:0007292 74 0.019
regulation of organ growth GO:0046620 61 0.018
cell type specific apoptotic process GO:0097285 268 0.018
myotube differentiation GO:0014902 105 0.018
negative regulation of neuron death GO:1901215 98 0.018
aromatic compound catabolic process GO:0019439 286 0.018
Human
regulation of protein complex assembly GO:0043254 83 0.018
Human
positive regulation of apoptotic process GO:0043065 217 0.018
Human
response to organonitrogen compound GO:0010243 246 0.018
Human
phagocytosis GO:0006909 66 0.018
organelle assembly GO:0070925 177 0.018
cellular response to dna damage stimulus GO:0006974 207 0.018
regulation of mammary gland epithelial cell proliferation GO:0033599 12 0.018
maintenance of presynaptic active zone structure GO:0048790 1 0.018
cell activation involved in immune response GO:0002263 126 0.018
lipid homeostasis GO:0055088 63 0.017
wnt signaling pathway GO:0016055 188 0.017
positive regulation of cell death GO:0010942 224 0.017
Human
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.017
learning GO:0007612 98 0.017
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 20 0.017
retina morphogenesis in camera type eye GO:0060042 45 0.017
dna metabolic process GO:0006259 303 0.017
notochord cell development GO:0060035 1 0.017
heterocycle catabolic process GO:0046700 280 0.017
Human
cellular response to cytokine stimulus GO:0071345 189 0.017
Human
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
Human
response to growth factor GO:0070848 198 0.017
Human
negative regulation of protein phosphorylation GO:0001933 126 0.017
Human
positive regulation of cell substrate adhesion GO:0010811 47 0.017
regulation of synapse assembly GO:0051963 29 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
limb development GO:0060173 166 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
Human
anion transport GO:0006820 177 0.017
respiratory system development GO:0060541 190 0.017
Fly
leukocyte proliferation GO:0070661 172 0.016
carbohydrate metabolic process GO:0005975 230 0.016
carbohydrate homeostasis GO:0033500 128 0.016
peptidyl amino acid modification GO:0018193 336 0.016
dephosphorylation GO:0016311 129 0.016
hippocampus development GO:0021766 52 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
Human
metal ion homeostasis GO:0055065 189 0.016
positive regulation of apoptotic signaling pathway GO:2001235 95 0.016
rho protein signal transduction GO:0007266 32 0.016
canonical wnt signaling pathway GO:0060070 130 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
actin polymerization or depolymerization GO:0008154 54 0.016
Human
response to radiation GO:0009314 165 0.016
neuroblast division in subventricular zone GO:0021849 2 0.016
spermatogenesis GO:0007283 284 0.016
protein localization to organelle GO:0033365 185 0.016
multi multicellular organism process GO:0044706 109 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
protein catabolic process GO:0030163 221 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
Human
cell substrate adhesion GO:0031589 130 0.015
tube formation GO:0035148 140 0.015
olfactory bulb axon guidance GO:0071678 1 0.015
regulation of striated muscle cell differentiation GO:0051153 81 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
Human
neuron projection regeneration GO:0031102 14 0.015
skeletal muscle organ development GO:0060538 163 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
Human
glycoprotein metabolic process GO:0009100 116 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
cognition GO:0050890 149 0.015
peptide secretion GO:0002790 114 0.015
male gamete generation GO:0048232 285 0.015
transmembrane transport GO:0055085 412 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
Human Zebrafish
ion transmembrane transport GO:0034220 361 0.015
cd4 positive alpha beta t cell activation GO:0035710 45 0.015
regulation of transferase activity GO:0051338 263 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
skeletal system morphogenesis GO:0048705 203 0.015
regulation of myelination GO:0031641 20 0.014
negative regulation of hormone biosynthetic process GO:0032353 4 0.014
adaptation of rhodopsin mediated signaling GO:0016062 2 0.014
regulation of secretion GO:0051046 274 0.014
synaptic vesicle membrane organization GO:0048499 1 0.014
insulin secretion GO:0030073 89 0.014
cell adhesion mediated by integrin GO:0033627 18 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
Human
posttranscriptional regulation of gene expression GO:0010608 155 0.014
regulation of secretion by cell GO:1903530 249 0.014
macromolecule catabolic process GO:0009057 281 0.014
lens development in camera type eye GO:0002088 62 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
Human
cranial nerve development GO:0021545 41 0.014
detection of abiotic stimulus GO:0009582 60 0.014
sulfur compound metabolic process GO:0006790 100 0.014
cytoplasmic transport GO:0016482 234 0.014
cell cell junction organization GO:0045216 72 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
Human
response to monosaccharide GO:0034284 67 0.014
positive regulation of neuron projection regeneration GO:0070572 2 0.014

Slit2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.338
urinary system disease DOID:18 0 0.338
central nervous system disease DOID:331 0 0.019
nervous system disease DOID:863 0 0.019