Mus musculus

0 known processes

Plbd2

phospholipase B domain containing 2

(Aliases: 1300012G16Rik,P76,AU019810)

Plbd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
natural killer cell degranulation GO:0043320 3 0.704
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.428
establishment of protein localization to organelle GO:0072594 118 0.313
natural killer cell activation involved in immune response GO:0002323 10 0.306
regulation of natural killer cell activation GO:0032814 22 0.244
vacuole organization GO:0007033 38 0.173
protein localization to organelle GO:0033365 185 0.172
regulation of vesicle mediated transport GO:0060627 139 0.148
cytoskeleton dependent intracellular transport GO:0030705 50 0.140
lysosomal transport GO:0007041 10 0.136
cytoplasmic transport GO:0016482 234 0.136
natural killer cell activation GO:0030101 44 0.127
microtubule based transport GO:0010970 50 0.118
cation transport GO:0006812 399 0.115
regulation of defense response GO:0031347 233 0.108
positive regulation of defense response GO:0031349 124 0.105
regulation of secretion by cell GO:1903530 249 0.088
macromolecule catabolic process GO:0009057 281 0.084
positive regulation of leukocyte mediated immunity GO:0002705 70 0.080
membrane organization GO:0061024 245 0.078
cellular amino acid metabolic process GO:0006520 103 0.078
transmembrane transport GO:0055085 412 0.076
leukocyte mediated cytotoxicity GO:0001909 62 0.074
positive regulation of cell activation GO:0050867 158 0.072
regulation of innate immune response GO:0045088 91 0.071
glycoprotein biosynthetic process GO:0009101 89 0.070
carbohydrate metabolic process GO:0005975 230 0.069
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.069
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.069
exocytosis GO:0006887 121 0.068
endocytosis GO:0006897 168 0.068
ras protein signal transduction GO:0007265 77 0.068
organelle transport along microtubule GO:0072384 14 0.067
ion transmembrane transport GO:0034220 361 0.066
protein modification by small protein conjugation GO:0032446 187 0.065
cation transmembrane transport GO:0098655 266 0.064
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.063
positive regulation of immune effector process GO:0002699 107 0.062
regulation of lymphocyte mediated immunity GO:0002706 84 0.061
regulation of intracellular transport GO:0032386 159 0.060
negative regulation of cellular protein metabolic process GO:0032269 247 0.060
microtubule based process GO:0007017 236 0.058
proteoglycan metabolic process GO:0006029 38 0.056
anion transport GO:0006820 177 0.055
regulation of secretion GO:0051046 274 0.055
regulation of lymphocyte activation GO:0051249 240 0.055
anion transmembrane transport GO:0098656 71 0.054
posttranscriptional regulation of gene expression GO:0010608 155 0.053
organic acid transport GO:0015849 101 0.053
positive regulation of secretion by cell GO:1903532 114 0.052
lymphocyte mediated immunity GO:0002449 139 0.050
nitrogen compound transport GO:0071705 271 0.049
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.049
amino acid transmembrane transport GO:0003333 37 0.048
regulation of leukocyte mediated immunity GO:0002703 104 0.048
lipid transport GO:0006869 98 0.046
organic anion transport GO:0015711 137 0.045
positive regulation of cell killing GO:0031343 33 0.045
apoptotic signaling pathway GO:0097190 306 0.045
glycosyl compound catabolic process GO:1901658 206 0.044
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.043
cellular homeostasis GO:0019725 240 0.043
glycoprotein metabolic process GO:0009100 116 0.042
positive regulation of innate immune response GO:0045089 80 0.042
positive regulation of secretion GO:0051047 130 0.040
leukocyte mediated immunity GO:0002443 174 0.040
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.039
regulation of microtubule based process GO:0032886 52 0.038
cellular response to hormone stimulus GO:0032870 150 0.038
regulation of cell killing GO:0031341 40 0.038
cellular ketone metabolic process GO:0042180 84 0.038
regulation of cell activation GO:0050865 289 0.038
carbohydrate derivative biosynthetic process GO:1901137 183 0.037
regulation of protein localization GO:0032880 231 0.037
protein localization to membrane GO:0072657 108 0.036
lysosome organization GO:0007040 21 0.036
vacuolar transport GO:0007034 11 0.036
glycerolipid metabolic process GO:0046486 122 0.036
regulation of cellular amine metabolic process GO:0033238 20 0.036
negative regulation of intracellular signal transduction GO:1902532 167 0.035
cellular response to growth factor stimulus GO:0071363 197 0.035
cellular amine metabolic process GO:0044106 44 0.034
innate immune response GO:0045087 157 0.034
positive regulation of lymphocyte activation GO:0051251 140 0.034
inflammatory response GO:0006954 244 0.034
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
intracellular protein transport GO:0006886 204 0.033
small gtpase mediated signal transduction GO:0007264 97 0.033
sulfur compound metabolic process GO:0006790 100 0.033
nucleoside phosphate metabolic process GO:0006753 338 0.032
regulation of regulated secretory pathway GO:1903305 20 0.032
immune effector process GO:0002252 321 0.032
cell matrix adhesion GO:0007160 68 0.032
regulation of exocytosis GO:0017157 61 0.031
cellular response to organonitrogen compound GO:0071417 145 0.031
response to organonitrogen compound GO:0010243 246 0.031
guanosine containing compound metabolic process GO:1901068 144 0.030
metal ion homeostasis GO:0055065 189 0.030
developmental growth involved in morphogenesis GO:0060560 138 0.030
organonitrogen compound catabolic process GO:1901565 264 0.030
organonitrogen compound biosynthetic process GO:1901566 192 0.030
rab protein signal transduction GO:0032482 1 0.029
leukocyte degranulation GO:0043299 27 0.029
gland development GO:0048732 330 0.029
reactive oxygen species metabolic process GO:0072593 84 0.028
inorganic cation transmembrane transport GO:0098662 207 0.028
synaptic transmission GO:0007268 329 0.028
positive regulation of regulated secretory pathway GO:1903307 10 0.028
natural killer cell mediated cytotoxicity GO:0042267 29 0.028
amine metabolic process GO:0009308 45 0.027
extracellular matrix organization GO:0030198 147 0.027
oxidation reduction process GO:0055114 342 0.027
sensory perception GO:0007600 245 0.027
carboxylic acid transport GO:0046942 100 0.027
reactive oxygen species biosynthetic process GO:1903409 8 0.026
lipid biosynthetic process GO:0008610 179 0.026
mucopolysaccharide metabolic process GO:1903510 25 0.026
protein processing GO:0016485 163 0.025
nucleotide metabolic process GO:0009117 332 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
hexose metabolic process GO:0019318 98 0.025
macromolecule glycosylation GO:0043413 55 0.025
regulated secretory pathway GO:0045055 32 0.025
cell killing GO:0001906 67 0.025
regulation of membrane potential GO:0042391 192 0.025
proteoglycan biosynthetic process GO:0030166 20 0.024
vesicle localization GO:0051648 86 0.024
reactive nitrogen species metabolic process GO:2001057 0 0.024
response to peptide GO:1901652 136 0.024
sphingolipid metabolic process GO:0006665 45 0.024
glycosaminoglycan metabolic process GO:0030203 34 0.024
positive regulation of protein modification process GO:0031401 299 0.023
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.023
glycosylation GO:0070085 62 0.023
plasma membrane organization GO:0007009 90 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
mapk cascade GO:0000165 281 0.023
regulation of protein stability GO:0031647 52 0.023
multicellular organismal signaling GO:0035637 91 0.023
respiratory system development GO:0060541 190 0.022
purine containing compound metabolic process GO:0072521 311 0.022
positive regulation of natural killer cell activation GO:0032816 15 0.022
phagocytosis GO:0006909 66 0.022
regulation of cellular ketone metabolic process GO:0010565 66 0.021
cell adhesion GO:0007155 329 0.021
amino acid transport GO:0006865 61 0.021
golgi vesicle transport GO:0048193 30 0.021
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.021
heterocycle catabolic process GO:0046700 280 0.021
locomotory behavior GO:0007626 195 0.021
vesicle organization GO:0016050 60 0.021
cellular chemical homeostasis GO:0055082 215 0.021
smoothened signaling pathway GO:0007224 105 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
natural killer cell mediated immunity GO:0002228 29 0.021
regulation of leukocyte degranulation GO:0043300 20 0.020
cellular response to molecule of bacterial origin GO:0071219 83 0.020
protein maturation GO:0051604 176 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.020
membrane protein proteolysis GO:0033619 10 0.019
lymphocyte activation involved in immune response GO:0002285 93 0.019
insulin receptor signaling pathway GO:0008286 49 0.019
endomembrane system organization GO:0010256 147 0.019
learning or memory GO:0007611 148 0.019
cation homeostasis GO:0055080 212 0.019
bone development GO:0060348 120 0.019
aromatic compound catabolic process GO:0019439 286 0.019
mitochondrion organization GO:0007005 134 0.019
cell activation involved in immune response GO:0002263 126 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
divalent inorganic cation transport GO:0072511 178 0.018
positive regulation of exocytosis GO:0045921 20 0.018
response to extracellular stimulus GO:0009991 127 0.018
ameboidal type cell migration GO:0001667 128 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.018
regulation of smoothened signaling pathway GO:0008589 58 0.018
maintenance of location GO:0051235 89 0.018
renal system development GO:0072001 225 0.018
lipid localization GO:0010876 126 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
response to peptide hormone GO:0043434 127 0.018
cellular modified amino acid metabolic process GO:0006575 63 0.018
response to organic cyclic compound GO:0014070 198 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
membrane lipid metabolic process GO:0006643 53 0.018
lateral inhibition GO:0046331 1 0.018
extracellular structure organization GO:0043062 148 0.017
response to growth factor GO:0070848 198 0.017
actin cytoskeleton organization GO:0030036 220 0.017
cell substrate adhesion GO:0031589 130 0.017
male gamete generation GO:0048232 285 0.017
monosaccharide metabolic process GO:0005996 106 0.017
cell growth GO:0016049 130 0.017
regulation of protein processing GO:0070613 96 0.017
cholesterol storage GO:0010878 4 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
single organism nuclear import GO:1902593 95 0.017
neuronal action potential GO:0019228 54 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
regulation of ion transport GO:0043269 215 0.017
protein ubiquitination GO:0016567 171 0.017
axonogenesis GO:0007409 274 0.017
establishment of vesicle localization GO:0051650 81 0.017
cellularization GO:0007349 1 0.017
regulation of angiotensin levels in blood GO:0002002 4 0.016
cellular component assembly involved in morphogenesis GO:0010927 139 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
regulation of mapk cascade GO:0043408 248 0.016
carbohydrate biosynthetic process GO:0016051 74 0.016
cellular response to nutrient levels GO:0031669 64 0.016
nuclear transport GO:0051169 139 0.016
nucleotide sugar metabolic process GO:0009225 4 0.016
aminoglycan metabolic process GO:0006022 34 0.016
cell junction organization GO:0034330 77 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
negative regulation of protein processing GO:0010955 79 0.016
regulation of cytokine production GO:0001817 266 0.016
purine containing compound catabolic process GO:0072523 213 0.015
regulation of anatomical structure size GO:0090066 178 0.015
positive regulation of necrotic cell death GO:0010940 1 0.015
cognition GO:0050890 149 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
spermatid differentiation GO:0048515 115 0.015
chemotaxis GO:0006935 247 0.015
regulation of organelle organization GO:0033043 289 0.015
positive regulation of cell death GO:0010942 224 0.015
protein import GO:0017038 101 0.015
membrane fusion GO:0061025 38 0.015
regulation of protein maturation GO:1903317 96 0.015
cellular metal ion homeostasis GO:0006875 151 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
stem cell differentiation GO:0048863 268 0.014
regulation of protein transport GO:0051223 163 0.014
ossification GO:0001503 216 0.014
nucleoside catabolic process GO:0009164 206 0.014
protein kinase b signaling GO:0043491 74 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.014
skeletal system morphogenesis GO:0048705 203 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
cell type specific apoptotic process GO:0097285 268 0.014
skeletal system development GO:0001501 356 0.014
sperm egg recognition GO:0035036 37 0.014
sulfur compound biosynthetic process GO:0044272 37 0.014
regulation of lipid transport GO:0032368 36 0.014
cellular lipid metabolic process GO:0044255 323 0.014
protein localization to plasma membrane GO:0072659 57 0.013
muscle contraction GO:0006936 101 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
negative regulation of molecular function GO:0044092 258 0.013
multicellular organism growth GO:0035264 161 0.013
autophagy GO:0006914 45 0.013
establishment of synaptic vesicle localization GO:0097480 57 0.013
glycosaminoglycan biosynthetic process GO:0006024 15 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
l amino acid transport GO:0015807 32 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
negative regulation of proteolysis GO:0045861 74 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
sodium ion transmembrane transport GO:0035725 49 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
organophosphate catabolic process GO:0046434 232 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
macroautophagy GO:0016236 21 0.013
t cell activation GO:0042110 289 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
response to amino acid GO:0043200 37 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
ceramide metabolic process GO:0006672 31 0.012
aminoglycan biosynthetic process GO:0006023 15 0.012
positive regulation of leukocyte degranulation GO:0043302 10 0.012
protein stabilization GO:0050821 25 0.012
response to lipopolysaccharide GO:0032496 128 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
protein targeting GO:0006605 143 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
amide transport GO:0042886 138 0.012
cell fate commitment GO:0045165 210 0.012
synaptic vesicle transport GO:0048489 57 0.012
rhythmic process GO:0048511 174 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
forebrain development GO:0030900 302 0.012
triglyceride metabolic process GO:0006641 51 0.012
t cell proliferation GO:0042098 120 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
cellular polysaccharide metabolic process GO:0044264 38 0.012
establishment of protein localization to vacuole GO:0072666 4 0.012
organelle assembly GO:0070925 177 0.012
muscle cell differentiation GO:0042692 261 0.011
glycerophospholipid metabolic process GO:0006650 71 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
cellular response to peptide GO:1901653 92 0.011
protein localization to vacuole GO:0072665 4 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
respiratory tube development GO:0030323 167 0.011
basement membrane assembly GO:0070831 2 0.011
compound eye development GO:0048749 1 0.011
positive regulation of growth GO:0045927 104 0.011
transmission of nerve impulse GO:0019226 76 0.011
interspecies interaction between organisms GO:0044419 83 0.011
neurotransmitter transport GO:0006836 76 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
regulation of proteolysis GO:0030162 164 0.011
rho protein signal transduction GO:0007266 32 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
sodium ion transport GO:0006814 73 0.011
synaptic vesicle localization GO:0097479 59 0.011
dendrite development GO:0016358 115 0.011
divalent metal ion transport GO:0070838 172 0.011
post golgi vesicle mediated transport GO:0006892 13 0.011
regionalization GO:0003002 337 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
regulation of cell motility GO:2000145 236 0.011
negative regulation of protein maturation GO:1903318 79 0.011
sterol homeostasis GO:0055092 45 0.011
nuclear import GO:0051170 95 0.011
learning GO:0007612 98 0.011
regulation of ras gtpase activity GO:0032318 88 0.011
cytokine production GO:0001816 319 0.011
glucose homeostasis GO:0042593 128 0.011
negative regulation of peptidase activity GO:0010466 46 0.011
regulation of cell migration GO:0030334 219 0.011
developmental cell growth GO:0048588 84 0.011
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
muscle system process GO:0003012 141 0.010
negative regulation of cell activation GO:0050866 111 0.010
regulation of transferase activity GO:0051338 263 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
cellular response to lipid GO:0071396 145 0.010
hindbrain development GO:0030902 128 0.010
positive regulation of nervous system development GO:0051962 221 0.010
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
regulation of lipid biosynthetic process GO:0046890 54 0.010
regulation of inflammatory response GO:0050727 147 0.010
calcium ion homeostasis GO:0055074 127 0.010
regulation of cell cycle GO:0051726 281 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
cellular ion homeostasis GO:0006873 165 0.010
peptide transport GO:0015833 133 0.010
epithelial cell development GO:0002064 159 0.010
protein glycosylation GO:0006486 55 0.010
regulation of hormone levels GO:0010817 211 0.010
nucleoside triphosphate metabolic process GO:0009141 230 0.010
muscle tissue development GO:0060537 308 0.010
blood circulation GO:0008015 195 0.010
polysaccharide metabolic process GO:0005976 39 0.010
skin development GO:0043588 220 0.010
regulation of endocytosis GO:0030100 69 0.010

Plbd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.113
musculoskeletal system disease DOID:17 0 0.113
disease of metabolism DOID:0014667 0 0.078
neuromuscular disease DOID:440 0 0.036
nervous system disease DOID:863 0 0.036
neuropathy DOID:870 0 0.036
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
muscular disease DOID:0080000 0 0.021
muscle tissue disease DOID:66 0 0.021
central nervous system disease DOID:331 0 0.017
organ system cancer DOID:0050686 0 0.015
charcot marie tooth disease DOID:10595 0 0.011
myopathy DOID:423 0 0.011
lysosomal storage disease DOID:3211 0 0.010
inherited metabolic disorder DOID:655 0 0.010