Mus musculus

51 known processes

Pikfyve

phosphoinositide kinase, FYVE finger containing

(Aliases: Pip5k3,p235,5230400C17Rik,Pip5k,Pipk5k3)

Pikfyve biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.234
cellular amino acid metabolic process GO:0006520 103 0.233
ras protein signal transduction GO:0007265 77 0.227
cellular amine metabolic process GO:0044106 44 0.202
regulation of mapk cascade GO:0043408 248 0.201
small gtpase mediated signal transduction GO:0007264 97 0.185
mapk cascade GO:0000165 281 0.183
amine metabolic process GO:0009308 45 0.175
cellular response to dna damage stimulus GO:0006974 207 0.175
synaptic transmission GO:0007268 329 0.174
cytoplasmic transport GO:0016482 234 0.168
axonogenesis GO:0007409 274 0.166
protein import GO:0017038 101 0.163
positive regulation of protein phosphorylation GO:0001934 242 0.163
protein localization to organelle GO:0033365 185 0.162
Human
aromatic compound catabolic process GO:0019439 286 0.159
heterocycle catabolic process GO:0046700 280 0.156
regulation of hydrolase activity GO:0051336 246 0.150
skeletal system development GO:0001501 356 0.148
positive regulation of kinase activity GO:0033674 155 0.148
cation transport GO:0006812 399 0.147
positive regulation of mapk cascade GO:0043410 170 0.140
regulation of ion transport GO:0043269 215 0.138
negative regulation of protein metabolic process GO:0051248 282 0.138
positive regulation of nervous system development GO:0051962 221 0.138
nucleoside triphosphate catabolic process GO:0009143 205 0.137
regulation of organelle organization GO:0033043 289 0.135
chemotaxis GO:0006935 247 0.132
forebrain development GO:0030900 302 0.132
axon guidance GO:0007411 141 0.131
leukocyte differentiation GO:0002521 342 0.129
regulation of cellular amino acid metabolic process GO:0006521 5 0.129
cellular nitrogen compound catabolic process GO:0044270 280 0.125
peptidyl serine phosphorylation GO:0018105 74 0.124
ribonucleoside triphosphate catabolic process GO:0009203 199 0.123
cellular ketone metabolic process GO:0042180 84 0.123
cell type specific apoptotic process GO:0097285 268 0.123
muscle cell differentiation GO:0042692 261 0.122
regionalization GO:0003002 337 0.120
ribonucleoside catabolic process GO:0042454 206 0.119
glycosyl compound catabolic process GO:1901658 206 0.117
ion transmembrane transport GO:0034220 361 0.116
regulation of cell projection organization GO:0031344 206 0.116
nuclear division GO:0000280 158 0.113
anatomical structure homeostasis GO:0060249 145 0.111
transmembrane transport GO:0055085 412 0.110
nucleoside phosphate metabolic process GO:0006753 338 0.110
regulation of cellular ketone metabolic process GO:0010565 66 0.110
learning or memory GO:0007611 148 0.108
purine ribonucleoside catabolic process GO:0046130 205 0.107
myeloid cell differentiation GO:0030099 233 0.107
purine nucleoside catabolic process GO:0006152 205 0.106
actin cytoskeleton organization GO:0030036 220 0.106
organelle fission GO:0048285 170 0.104
apoptotic signaling pathway GO:0097190 306 0.104
muscle tissue development GO:0060537 308 0.103
nucleotide catabolic process GO:0009166 217 0.102
organonitrogen compound catabolic process GO:1901565 264 0.101
regulation of apoptotic signaling pathway GO:2001233 197 0.099
negative regulation of cellular amine metabolic process GO:0033239 1 0.098
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.098
nucleoside triphosphate metabolic process GO:0009141 230 0.098
regulation of neuron projection development GO:0010975 169 0.095
nucleoside catabolic process GO:0009164 206 0.094
morphogenesis of a branching structure GO:0001763 203 0.093
skin development GO:0043588 220 0.093
cytokine production GO:0001816 319 0.092
positive regulation of protein modification process GO:0031401 299 0.091
purine nucleotide catabolic process GO:0006195 211 0.091
regulation of neuron differentiation GO:0045664 281 0.090
regulation of protein kinase activity GO:0045859 232 0.090
regulation of anatomical structure size GO:0090066 178 0.090
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.090
positive regulation of programmed cell death GO:0043068 218 0.089
intracellular protein transport GO:0006886 204 0.088
regulation of response to drug GO:2001023 2 0.086
carbohydrate derivative catabolic process GO:1901136 231 0.085
regulation of cellular response to stress GO:0080135 159 0.084
purine ribonucleoside metabolic process GO:0046128 241 0.083
positive regulation of cellular amine metabolic process GO:0033240 5 0.083
nucleoside phosphate catabolic process GO:1901292 222 0.082
regulation of transferase activity GO:0051338 263 0.080
cellular homeostasis GO:0019725 240 0.080
organelle localization GO:0051640 179 0.080
regulation of cellular amine metabolic process GO:0033238 20 0.079
nuclear transport GO:0051169 139 0.079
establishment of protein localization to organelle GO:0072594 118 0.079
myotube differentiation GO:0014902 105 0.078
response to organonitrogen compound GO:0010243 246 0.078
regulation of cell motility GO:2000145 236 0.076
hematopoietic progenitor cell differentiation GO:0002244 143 0.076
epithelial tube morphogenesis GO:0060562 303 0.076
bone development GO:0060348 120 0.076
regulation of protein serine threonine kinase activity GO:0071900 157 0.076
phagocytosis GO:0006909 66 0.075
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.075
regulation of cell migration GO:0030334 219 0.075
ribonucleotide catabolic process GO:0009261 208 0.074
histone modification GO:0016570 159 0.074
regulation of kinase activity GO:0043549 249 0.073
regulation of cellular catabolic process GO:0031329 242 0.073
renal system development GO:0072001 225 0.073
divalent metal ion transport GO:0070838 172 0.073
lung development GO:0030324 164 0.073
sensory organ morphogenesis GO:0090596 242 0.072
sensory perception GO:0007600 245 0.072
oxidation reduction process GO:0055114 342 0.071
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.071
negative regulation of phosphate metabolic process GO:0045936 184 0.071
endocytosis GO:0006897 168 0.071
nucleoside metabolic process GO:0009116 246 0.071
single organism nuclear import GO:1902593 95 0.071
blood vessel morphogenesis GO:0048514 285 0.071
organic cyclic compound catabolic process GO:1901361 295 0.071
peptidyl amino acid modification GO:0018193 336 0.071
respiratory system development GO:0060541 190 0.071
ribonucleoside triphosphate metabolic process GO:0009199 220 0.071
angiogenesis GO:0001525 201 0.070
purine nucleoside triphosphate catabolic process GO:0009146 203 0.070
positive regulation of protein kinase activity GO:0045860 144 0.070
glycosyl compound metabolic process GO:1901657 246 0.070
kidney development GO:0001822 213 0.070
purine nucleoside triphosphate metabolic process GO:0009144 226 0.070
rho protein signal transduction GO:0007266 32 0.069
skeletal system morphogenesis GO:0048705 203 0.068
neural tube development GO:0021915 160 0.068
purine containing compound catabolic process GO:0072523 213 0.067
cell recognition GO:0008037 83 0.066
mitotic cell cycle process GO:1903047 159 0.066
protein localization to nucleus GO:0034504 121 0.065
Human
regulation of binding GO:0051098 111 0.065
purine nucleoside metabolic process GO:0042278 241 0.065
positive regulation of organelle organization GO:0010638 128 0.064
regulation of nucleotide catabolic process GO:0030811 122 0.064
cellular response to growth factor stimulus GO:0071363 197 0.064
regulation of homeostatic process GO:0032844 182 0.063
dna repair GO:0006281 107 0.063
protein modification by small protein conjugation GO:0032446 187 0.063
dna metabolic process GO:0006259 303 0.063
purine ribonucleotide catabolic process GO:0009154 208 0.062
neural tube formation GO:0001841 108 0.062
regulation of hormone levels GO:0010817 211 0.062
ribonucleoside metabolic process GO:0009119 245 0.061
multicellular organism growth GO:0035264 161 0.061
purine nucleotide metabolic process GO:0006163 302 0.060
neuron projection guidance GO:0097485 141 0.060
cell division GO:0051301 120 0.060
regulation of transmembrane transport GO:0034762 128 0.060
embryonic placenta development GO:0001892 98 0.059
positive regulation of cell death GO:0010942 224 0.059
striated muscle tissue development GO:0014706 293 0.058
peptidyl serine modification GO:0018209 83 0.058
branching morphogenesis of an epithelial tube GO:0048754 159 0.058
myeloid leukocyte differentiation GO:0002573 119 0.057
regulation of embryonic development GO:0045995 71 0.057
divalent inorganic cation transport GO:0072511 178 0.057
immune effector process GO:0002252 321 0.057
palate development GO:0060021 76 0.056
protein targeting GO:0006605 143 0.056
chromatin organization GO:0006325 206 0.056
mitotic cell cycle GO:0000278 195 0.055
negative regulation of molecular function GO:0044092 258 0.055
regulation of cell activation GO:0050865 289 0.055
negative regulation of intracellular signal transduction GO:1902532 167 0.055
regulation of ras protein signal transduction GO:0046578 114 0.055
covalent chromatin modification GO:0016569 163 0.054
homeostasis of number of cells GO:0048872 210 0.053
meiotic cell cycle GO:0051321 122 0.053
regulation of secretion GO:0051046 274 0.053
glycerolipid metabolic process GO:0046486 122 0.052
positive regulation of cell motility GO:2000147 116 0.051
alpha beta t cell activation GO:0046631 91 0.051
stress activated mapk cascade GO:0051403 80 0.051
placenta development GO:0001890 140 0.051
nitrogen compound transport GO:0071705 271 0.051
protein kinase b signaling GO:0043491 74 0.051
regulation of map kinase activity GO:0043405 120 0.051
ribonucleotide metabolic process GO:0009259 291 0.050
leukocyte activation involved in immune response GO:0002366 126 0.050
defecation GO:0030421 1 0.049
mitochondrion distribution GO:0048311 4 0.049
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.049
membrane organization GO:0061024 245 0.049
action potential GO:0001508 78 0.048
positive regulation of apoptotic process GO:0043065 217 0.048
heart morphogenesis GO:0003007 178 0.048
morphogenesis of a branching epithelium GO:0061138 193 0.048
positive regulation of lymphocyte activation GO:0051251 140 0.048
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.048
positive regulation of cell development GO:0010720 237 0.048
inorganic ion transmembrane transport GO:0098660 234 0.047
urogenital system development GO:0001655 261 0.047
nucleobase containing small molecule metabolic process GO:0055086 352 0.047
regulation of peptidyl serine phosphorylation GO:0033135 39 0.047
response to molecule of bacterial origin GO:0002237 143 0.047
ear development GO:0043583 200 0.047
cell activation involved in immune response GO:0002263 126 0.047
limb development GO:0060173 166 0.047
erk1 and erk2 cascade GO:0070371 77 0.046
respiratory tube development GO:0030323 167 0.046
positive regulation of neuron differentiation GO:0045666 141 0.046
cellular macromolecule catabolic process GO:0044265 206 0.046
wnt signaling pathway GO:0016055 188 0.046
epithelial cell proliferation GO:0050673 174 0.046
protein polymerization GO:0051258 57 0.045
germ cell development GO:0007281 185 0.045
telencephalon development GO:0021537 186 0.045
ribose phosphate metabolic process GO:0019693 291 0.044
regulation of vesicle mediated transport GO:0060627 139 0.044
positive regulation of cell cycle GO:0045787 92 0.044
stress activated protein kinase signaling cascade GO:0031098 81 0.044
canonical wnt signaling pathway GO:0060070 130 0.043
innate immune response GO:0045087 157 0.043
primary neural tube formation GO:0014020 95 0.043
g protein coupled receptor signaling pathway GO:0007186 243 0.043
ameboidal type cell migration GO:0001667 128 0.042
cellular response to inorganic substance GO:0071241 37 0.042
regulation of lymphocyte activation GO:0051249 240 0.042
positive regulation of transferase activity GO:0051347 167 0.042
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.042
negative regulation of cell proliferation GO:0008285 296 0.041
nuclear import GO:0051170 95 0.041
positive regulation of cell activation GO:0050867 158 0.041
blood circulation GO:0008015 195 0.040
tube closure GO:0060606 91 0.040
cerebellum development GO:0021549 77 0.040
regulation of cell cycle GO:0051726 281 0.040
cellular response to organonitrogen compound GO:0071417 145 0.040
purine containing compound metabolic process GO:0072521 311 0.040
positive regulation of cell migration GO:0030335 109 0.040
negative regulation of phosphorylation GO:0042326 166 0.040
tissue homeostasis GO:0001894 115 0.039
cellular response to lipid GO:0071396 145 0.039
regulation of nucleoside metabolic process GO:0009118 130 0.039
multi multicellular organism process GO:0044706 109 0.039
t cell activation GO:0042110 289 0.039
rac protein signal transduction GO:0016601 13 0.039
macromolecule catabolic process GO:0009057 281 0.039
protein ubiquitination GO:0016567 171 0.038
metal ion homeostasis GO:0055065 189 0.038
double strand break repair GO:0006302 48 0.038
gliogenesis GO:0042063 141 0.038
positive regulation of apoptotic signaling pathway GO:2001235 95 0.038
regulation of protein binding GO:0043393 60 0.038
chromatin modification GO:0016568 187 0.038
multicellular organismal homeostasis GO:0048871 164 0.038
development of primary sexual characteristics GO:0045137 143 0.038
mitochondrion organization GO:0007005 134 0.037
camera type eye development GO:0043010 266 0.037
regulation of purine nucleotide catabolic process GO:0033121 122 0.037
regulation of erk1 and erk2 cascade GO:0070372 71 0.037
protein import into nucleus GO:0006606 95 0.037
protein processing GO:0016485 163 0.037
exocytosis GO:0006887 121 0.037
response to inorganic substance GO:0010035 96 0.037
somite development GO:0061053 81 0.037
negative regulation of ripoptosome assembly involved in necroptotic process GO:1902443 3 0.036
intracellular receptor signaling pathway GO:0030522 74 0.036
embryonic organ morphogenesis GO:0048562 276 0.036
meiotic nuclear division GO:0007126 115 0.036
response to lipopolysaccharide GO:0032496 128 0.036
response to light stimulus GO:0009416 135 0.036
inorganic cation transmembrane transport GO:0098662 207 0.036
organophosphate catabolic process GO:0046434 232 0.036
axonal fasciculation GO:0007413 15 0.036
protein modification by small protein conjugation or removal GO:0070647 207 0.035
spermatogenesis GO:0007283 284 0.035
cognition GO:0050890 149 0.035
extracellular matrix organization GO:0030198 147 0.035
sodium ion transport GO:0006814 73 0.035
negative regulation of cellular component organization GO:0051129 194 0.034
extrinsic apoptotic signaling pathway GO:0097191 126 0.034
circulatory system process GO:0003013 197 0.034
regulation of system process GO:0044057 200 0.034
blood coagulation GO:0007596 76 0.034
gland development GO:0048732 330 0.034
protein maturation GO:0051604 176 0.033
regulation of cellular component size GO:0032535 121 0.033
epidermis development GO:0008544 187 0.033
regulation of cell size GO:0008361 72 0.033
regulation of stress activated mapk cascade GO:0032872 69 0.032
appendage development GO:0048736 166 0.032
intestinal epithelial structure maintenance GO:0060729 4 0.032
regulation of leukocyte differentiation GO:1902105 159 0.032
morphogenesis of embryonic epithelium GO:0016331 159 0.032
fertilization GO:0009566 127 0.032
myelination GO:0042552 74 0.032
guanosine containing compound metabolic process GO:1901068 144 0.032
lymphocyte activation involved in immune response GO:0002285 93 0.031
stem cell proliferation GO:0072089 117 0.031
carbohydrate metabolic process GO:0005975 230 0.031
intrinsic apoptotic signaling pathway GO:0097193 132 0.031
endodermal cell fate specification GO:0001714 4 0.031
body morphogenesis GO:0010171 45 0.031
calcium ion transport GO:0006816 159 0.031
guanosine containing compound catabolic process GO:1901069 144 0.031
multicellular organismal signaling GO:0035637 91 0.031
cellular protein complex assembly GO:0043623 116 0.030
nucleotide metabolic process GO:0009117 332 0.030
regulation of ion transmembrane transport GO:0034765 119 0.030
glial cell differentiation GO:0010001 131 0.030
nucleocytoplasmic transport GO:0006913 139 0.030
dna recombination GO:0006310 92 0.030
inflammatory response GO:0006954 244 0.029
retina development in camera type eye GO:0060041 119 0.029
regulation of gtp catabolic process GO:0033124 113 0.029
regulation of body fluid levels GO:0050878 162 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
positive regulation of defense response GO:0031349 124 0.029
bmp signaling pathway GO:0030509 93 0.029
regulation of transporter activity GO:0032409 57 0.029
muscle cell development GO:0055001 133 0.029
cellular response to lipopolysaccharide GO:0071222 77 0.029
fat cell differentiation GO:0045444 160 0.029
positive regulation of gtpase activity GO:0043547 85 0.028
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.028
face development GO:0060324 38 0.028
positive regulation of nucleoside metabolic process GO:0045979 91 0.028
leukocyte migration GO:0050900 124 0.028
regulation of cytoplasmic transport GO:1903649 112 0.028
calcium ion homeostasis GO:0055074 127 0.028
cellular carbohydrate metabolic process GO:0044262 119 0.028
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.028
modification dependent protein catabolic process GO:0019941 133 0.028
ensheathment of neurons GO:0007272 76 0.028
gtp metabolic process GO:0046039 144 0.028
hemostasis GO:0007599 78 0.028
endomembrane system organization GO:0010256 147 0.028
smoothened signaling pathway GO:0007224 105 0.027
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.027
embryonic appendage morphogenesis GO:0035113 126 0.027
inner ear morphogenesis GO:0042472 101 0.027
regulation of nuclear division GO:0051783 56 0.027
reactive oxygen species metabolic process GO:0072593 84 0.027
regulation of cell division GO:0051302 76 0.027
central nervous system neuron differentiation GO:0021953 162 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
regulation of wnt signaling pathway GO:0030111 123 0.027
establishment of organelle localization GO:0051656 122 0.027
nerve development GO:0021675 67 0.027
actin filament organization GO:0007015 113 0.026
regulation of neuron apoptotic process GO:0043523 122 0.026
cell growth GO:0016049 130 0.026
positive regulation of stress activated mapk cascade GO:0032874 48 0.026
negative regulation of growth GO:0045926 99 0.026
developmental maturation GO:0021700 193 0.026
skeletal muscle organ development GO:0060538 163 0.026
ear morphogenesis GO:0042471 118 0.026
leukocyte proliferation GO:0070661 172 0.026
regulation of protein processing GO:0070613 96 0.026
response to peptide GO:1901652 136 0.026
cellular response to peptide GO:1901653 92 0.026
digestive tract development GO:0048565 190 0.026
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.026
stem cell differentiation GO:0048863 268 0.026
pallium development GO:0021543 120 0.026
jnk cascade GO:0007254 72 0.026
regulation of t cell activation GO:0050863 170 0.025
memory GO:0007613 58 0.025
phosphatidylinositol metabolic process GO:0046488 45 0.025
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.025
cell adhesion GO:0007155 329 0.025
embryonic limb morphogenesis GO:0030326 126 0.025
synaptic vesicle transport GO:0048489 57 0.025
protein catabolic process GO:0030163 221 0.025
embryonic digit morphogenesis GO:0042733 56 0.025
positive regulation of ras gtpase activity GO:0032320 65 0.025
single fertilization GO:0007338 82 0.025
meiotic cell cycle process GO:1903046 77 0.025
axon ensheathment GO:0008366 76 0.025
cell aging GO:0007569 35 0.025
peptidyl lysine modification GO:0018205 77 0.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.025
maintenance of location GO:0051235 89 0.025
microtubule based movement GO:0007018 84 0.024
digestive system development GO:0055123 200 0.024
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.024
gastrulation GO:0007369 116 0.024
heparin biosynthetic process GO:0030210 2 0.024
locomotory behavior GO:0007626 195 0.024
regulation of tumor necrosis factor production GO:0032680 49 0.024
positive regulation of hydrolase activity GO:0051345 148 0.024
gtp catabolic process GO:0006184 143 0.024
negative regulation of synaptic vesicle transport GO:1902804 3 0.024
negative regulation of cell development GO:0010721 169 0.024
activation of adenylate cyclase activity GO:0007190 4 0.024
cardiac ventricle development GO:0003231 83 0.023
cellular ion homeostasis GO:0006873 165 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.023
sympathetic neuron projection guidance GO:0097491 4 0.023
lipid localization GO:0010876 126 0.023
regulation of cell shape GO:0008360 39 0.023
response to growth factor GO:0070848 198 0.023
regulation of ras gtpase activity GO:0032318 88 0.023
tumor necrosis factor production GO:0032640 50 0.023
response to radiation GO:0009314 165 0.023
glucose homeostasis GO:0042593 128 0.023
vesicle localization GO:0051648 86 0.023
regulation of jnk cascade GO:0046328 62 0.023
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.023
positive regulation of map kinase activity GO:0043406 84 0.023
synaptic vesicle localization GO:0097479 59 0.023
tissue remodeling GO:0048771 102 0.023
neuron projection extension GO:1990138 64 0.023
neuron migration GO:0001764 122 0.023
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
lymphocyte differentiation GO:0030098 242 0.022
regulation of phospholipase c activity GO:1900274 3 0.022
cation homeostasis GO:0055080 212 0.022
wound healing GO:0042060 157 0.022
cellular metal ion homeostasis GO:0006875 151 0.022
regulation of endopeptidase activity GO:0052548 89 0.022
cellular chemical homeostasis GO:0055082 215 0.022
retrograde transport endosome to golgi GO:0042147 2 0.022
Human
embryonic hemopoiesis GO:0035162 23 0.022
negative regulation of nervous system development GO:0051961 156 0.022
extracellular structure organization GO:0043062 148 0.022
regulation of canonical wnt signaling pathway GO:0060828 82 0.022
cytoskeleton dependent intracellular transport GO:0030705 50 0.022
activation of immune response GO:0002253 138 0.022
embryonic skeletal system development GO:0048706 120 0.022
cardiac septum development GO:0003279 59 0.022
alpha beta t cell differentiation GO:0046632 69 0.022
microtubule based process GO:0007017 236 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.022
regulation of membrane potential GO:0042391 192 0.021
regulation of cytokine production GO:0001817 266 0.021
monocarboxylic acid metabolic process GO:0032787 191 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.021
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.021
phospholipid metabolic process GO:0006644 87 0.021
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.021
stem cell development GO:0048864 219 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
dendrite development GO:0016358 115 0.021
cellular calcium ion homeostasis GO:0006874 119 0.021
positive regulation of cell projection organization GO:0031346 95 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
tube formation GO:0035148 140 0.021
immune response activating signal transduction GO:0002757 116 0.021
synapse organization GO:0050808 125 0.021
regulation of defense response GO:0031347 233 0.020
positive regulation of growth GO:0045927 104 0.020
positive regulation of leukocyte mediated immunity GO:0002705 70 0.020
regulation of voltage gated calcium channel activity GO:1901385 4 0.020
mitotic nuclear division GO:0007067 48 0.020
negative regulation of ras protein signal transduction GO:0046580 18 0.020
appendage morphogenesis GO:0035107 149 0.020
ossification GO:0001503 216 0.020
modification dependent macromolecule catabolic process GO:0043632 133 0.020
carbohydrate homeostasis GO:0033500 128 0.020
cation transmembrane transport GO:0098655 266 0.020
mesenchyme development GO:0060485 152 0.020
forebrain neuron development GO:0021884 30 0.020
negative regulation of apoptotic signaling pathway GO:2001234 104 0.020
negative regulation of immune system process GO:0002683 209 0.020
positive regulation of jnk cascade GO:0046330 46 0.020
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.020
negative regulation of hydrolase activity GO:0051346 71 0.020
regulation of protein localization GO:0032880 231 0.020
regulation of protein maturation GO:1903317 96 0.020
muscle system process GO:0003012 141 0.020
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.020
bone resorption GO:0045453 38 0.020
lymphocyte mediated immunity GO:0002449 139 0.019
peptidyl threonine phosphorylation GO:0018107 31 0.019
positive regulation of epithelial cell proliferation GO:0050679 68 0.019
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.019
response to acid chemical GO:0001101 111 0.019
developmental growth involved in morphogenesis GO:0060560 138 0.019
regulation of blood pressure GO:0008217 93 0.019
positive regulation of innate immune response GO:0045089 80 0.019
actin polymerization or depolymerization GO:0008154 54 0.019
cellular protein catabolic process GO:0044257 155 0.019
metencephalon development GO:0022037 89 0.019
regulation of cation channel activity GO:2001257 22 0.019
regulation of intracellular transport GO:0032386 159 0.019
response to organic cyclic compound GO:0014070 198 0.019
regulation of neurotransmitter levels GO:0001505 87 0.019
cardiac chamber morphogenesis GO:0003206 93 0.019
hindlimb morphogenesis GO:0035137 42 0.019
endocardial cushion morphogenesis GO:0003203 18 0.019
negative regulation of neuron death GO:1901215 98 0.019
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.019
regulation of ion transmembrane transporter activity GO:0032412 54 0.019

Pikfyve disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.031
disease of anatomical entity DOID:7 0 0.031
musculoskeletal system disease DOID:17 0 0.031
connective tissue disease DOID:65 0 0.031
nervous system disease DOID:863 0 0.029
immune system disease DOID:2914 0 0.022