Mus musculus

149 known processes

Slc40a1

solute carrier family 40 (iron-regulated transporter), member 1

(Aliases: IREG1,Slc11a3,MTP,Dusg,Fpn1,MTP1,Ol5,Pcm,Slc39a1)

Slc40a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
iron ion homeostasis GO:0055072 36 0.997
iron ion import GO:0097286 5 0.995
myeloid cell homeostasis GO:0002262 114 0.986
Zebrafish
erythrocyte differentiation GO:0030218 88 0.973
Zebrafish
cation homeostasis GO:0055080 212 0.942
multicellular organismal iron ion homeostasis GO:0060586 8 0.940
cation transport GO:0006812 399 0.934
response to iron ion GO:0010039 4 0.928
transition metal ion homeostasis GO:0055076 54 0.885
oxidation reduction process GO:0055114 342 0.856
glutathione metabolic process GO:0006749 16 0.788
transition metal ion transport GO:0000041 38 0.732
cofactor metabolic process GO:0051186 80 0.723
iron ion transport GO:0006826 17 0.707
homeostasis of number of cells GO:0048872 210 0.641
myeloid cell differentiation GO:0030099 233 0.627
Zebrafish
iron ion import into cell GO:0097459 4 0.614
metal ion homeostasis GO:0055065 189 0.549
blood coagulation GO:0007596 76 0.535
response to oxidative stress GO:0006979 123 0.519
porphyrin containing compound metabolic process GO:0006778 22 0.518
cellular metal ion homeostasis GO:0006875 151 0.512
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.511
cytokine production GO:0001816 319 0.485
tetrapyrrole metabolic process GO:0033013 22 0.473
wound healing GO:0042060 157 0.459
copper ion transport GO:0006825 10 0.447
coagulation GO:0050817 78 0.444
positive regulation of cell death GO:0010942 224 0.429
t cell activation GO:0042110 289 0.416
cellular iron ion homeostasis GO:0006879 16 0.394
t cell activation involved in immune response GO:0002286 43 0.382
hemostasis GO:0007599 78 0.354
trivalent inorganic cation transport GO:0072512 5 0.353
cellular transition metal ion homeostasis GO:0046916 32 0.333
leukocyte activation involved in immune response GO:0002366 126 0.311
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.289
regulation of t cell mediated cytotoxicity GO:0001914 18 0.288
antigen processing and presentation GO:0019882 47 0.286
t cell mediated immunity GO:0002456 50 0.279
cellular response to arsenic containing substance GO:0071243 4 0.271
antigen processing and presentation of peptide antigen GO:0048002 29 0.266
inorganic ion transmembrane transport GO:0098660 234 0.263
cell killing GO:0001906 67 0.238
regulation of apoptotic signaling pathway GO:2001233 197 0.236
immune effector process GO:0002252 321 0.235
copper ion transmembrane transport GO:0035434 5 0.234
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.228
response to molecule of bacterial origin GO:0002237 143 0.226
positive regulation of defense response GO:0031349 124 0.221
cellular amino acid metabolic process GO:0006520 103 0.204
cell activation involved in immune response GO:0002263 126 0.204
cytokine production involved in immune response GO:0002367 34 0.202
heme metabolic process GO:0042168 16 0.198
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.195
lymphocyte proliferation GO:0046651 164 0.195
reactive oxygen species biosynthetic process GO:1903409 8 0.190
posttranscriptional regulation of gene expression GO:0010608 155 0.176
organic anion transport GO:0015711 137 0.174
hormone metabolic process GO:0042445 86 0.174
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.171
arginine transport GO:0015809 4 0.171
t cell mediated cytotoxicity GO:0001913 26 0.166
leukocyte differentiation GO:0002521 342 0.165
lymphocyte mediated immunity GO:0002449 139 0.163
cofactor biosynthetic process GO:0051188 41 0.163
response to metal ion GO:0010038 47 0.161
myeloid leukocyte differentiation GO:0002573 119 0.157
reactive oxygen species metabolic process GO:0072593 84 0.154
regulation of cytokine production GO:0001817 266 0.152
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.149
heme biosynthetic process GO:0006783 12 0.148
response to starvation GO:0042594 65 0.146
defense response to bacterium GO:0042742 119 0.142
positive regulation of apoptotic process GO:0043065 217 0.140
inorganic cation import into cell GO:0098659 4 0.139
production of molecular mediator of immune response GO:0002440 103 0.138
regulation of natural killer cell mediated immunity GO:0002715 19 0.133
pigment metabolic process GO:0042440 32 0.133
response to lipopolysaccharide GO:0032496 128 0.133
folic acid containing compound metabolic process GO:0006760 3 0.131
positive regulation of cytokine production GO:0001819 174 0.130
anion transport GO:0006820 177 0.122
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.122
positive regulation of phagocytosis GO:0050766 26 0.120
ion transmembrane transport GO:0034220 361 0.119
regulation of cellular catabolic process GO:0031329 242 0.118
transmembrane transport GO:0055085 412 0.117
organ regeneration GO:0031100 2 0.117
circulatory system process GO:0003013 197 0.114
leukocyte mediated immunity GO:0002443 174 0.114
multicellular organismal homeostasis GO:0048871 164 0.114
antigen processing and presentation of exogenous peptide antigen via mhc class ib GO:0002477 3 0.111
cellular chemical homeostasis GO:0055082 215 0.111
porphyrin containing compound biosynthetic process GO:0006779 16 0.110
regulation of ion transport GO:0043269 215 0.109
interferon gamma production GO:0032609 67 0.108
tetrapyrrole biosynthetic process GO:0033014 16 0.104
regulation of body fluid levels GO:0050878 162 0.103
adaptive immune response GO:0002250 155 0.100
regulation of cellular ketone metabolic process GO:0010565 66 0.100
cofactor catabolic process GO:0051187 6 0.099
sulfur compound metabolic process GO:0006790 100 0.099
regulation of hormone levels GO:0010817 211 0.098
reactive nitrogen species metabolic process GO:2001057 0 0.098
gland development GO:0048732 330 0.096
cellular homeostasis GO:0019725 240 0.095
regulation of leukocyte mediated immunity GO:0002703 104 0.093
organic acid transport GO:0015849 101 0.091
leukocyte proliferation GO:0070661 172 0.091
regulation of defense response GO:0031347 233 0.091
response to hypoxia GO:0001666 58 0.087
cellular ion homeostasis GO:0006873 165 0.087
regulation of translation GO:0006417 71 0.087
lymphocyte activation involved in immune response GO:0002285 93 0.087
import into cell GO:0098657 8 0.086
sensory perception GO:0007600 245 0.084
positive regulation of apoptotic signaling pathway GO:2001235 95 0.083
inorganic cation transmembrane transport GO:0098662 207 0.083
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.081
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.079
lymphocyte homeostasis GO:0002260 64 0.077
blood circulation GO:0008015 195 0.075
nitrogen compound transport GO:0071705 271 0.072
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 10 0.071
divalent metal ion transport GO:0070838 172 0.070
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 4 0.070
response to inorganic substance GO:0010035 96 0.069
interleukin 2 production GO:0032623 33 0.068
translation GO:0006412 93 0.068
regulation of transcription from rna polymerase ii promoter in response to iron GO:0034395 3 0.067
regulation of translational initiation in response to stress GO:0043558 5 0.067
positive regulation of cell killing GO:0031343 33 0.066
cellular response to oxidative stress GO:0034599 76 0.065
inorganic anion transport GO:0015698 43 0.065
innate immune response GO:0045087 157 0.064
positive regulation of protein modification process GO:0031401 299 0.064
positive regulation of programmed cell death GO:0043068 218 0.063
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.063
positive regulation of innate immune response GO:0045089 80 0.062
positive regulation of adaptive immune response GO:0002821 61 0.062
cell maturation GO:0048469 127 0.062
Zebrafish
cellular response to extracellular stimulus GO:0031668 81 0.062
natural killer cell mediated immunity GO:0002228 29 0.062
positive regulation of immune effector process GO:0002699 107 0.061
amino acid transport GO:0006865 61 0.061
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.060
regulation of lymphocyte mediated immunity GO:0002706 84 0.059
protein localization to organelle GO:0033365 185 0.059
response to extracellular stimulus GO:0009991 127 0.058
l amino acid transport GO:0015807 32 0.058
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 9 0.057
cellular amine metabolic process GO:0044106 44 0.057
t cell proliferation GO:0042098 120 0.057
cellular response to cadmium ion GO:0071276 3 0.057
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.056
modification dependent protein catabolic process GO:0019941 133 0.056
intrinsic apoptotic signaling pathway GO:0097193 132 0.056
coenzyme metabolic process GO:0006732 52 0.055
hydrogen ion transmembrane transport GO:1902600 25 0.055
learning or memory GO:0007611 148 0.055
apoptotic signaling pathway GO:0097190 306 0.054
organonitrogen compound biosynthetic process GO:1901566 192 0.054
signal transduction by p53 class mediator GO:0072331 51 0.054
cytoplasmic transport GO:0016482 234 0.054
negative regulation of cytokine production GO:0001818 84 0.052
regulation of adaptive immune response GO:0002819 90 0.052
organonitrogen compound catabolic process GO:1901565 264 0.052
regulation of interferon gamma production GO:0032649 57 0.050
acute inflammatory response GO:0002526 41 0.049
cellular response to nutrient levels GO:0031669 64 0.049
antigen processing and presentation of exogenous antigen GO:0019884 26 0.049
inflammatory response GO:0006954 244 0.049
digestive system development GO:0055123 200 0.048
pteridine containing compound metabolic process GO:0042558 5 0.047
regulation of cell activation GO:0050865 289 0.047
response to oxygen levels GO:0070482 62 0.047
alpha beta t cell activation GO:0046631 91 0.047
regulation of cell killing GO:0031341 40 0.047
hormone biosynthetic process GO:0042446 16 0.047
protein modification by small protein conjugation or removal GO:0070647 207 0.046
cellular protein catabolic process GO:0044257 155 0.046
regulation of cellular response to stress GO:0080135 159 0.045
cation transmembrane transport GO:0098655 266 0.045
cellular response to lipopolysaccharide GO:0071222 77 0.045
regulation of innate immune response GO:0045088 91 0.045
cellular amide metabolic process GO:0043603 58 0.044
positive regulation of cellular catabolic process GO:0031331 148 0.043
liver development GO:0001889 66 0.043
macromolecule catabolic process GO:0009057 281 0.042
protein ubiquitination GO:0016567 171 0.042
positive regulation of t cell mediated immunity GO:0002711 24 0.042
positive regulation of homeostatic process GO:0032846 64 0.041
positive regulation of peptidase activity GO:0010952 49 0.041
regulation of binding GO:0051098 111 0.041
positive regulation of endopeptidase activity GO:0010950 43 0.041
positive regulation of interferon gamma production GO:0032729 39 0.040
carboxylic acid transport GO:0046942 100 0.040
protein import GO:0017038 101 0.040
protein localization to nucleus GO:0034504 121 0.040
regulation of vesicle mediated transport GO:0060627 139 0.040
rho protein signal transduction GO:0007266 32 0.039
monosaccharide metabolic process GO:0005996 106 0.039
hepaticobiliary system development GO:0061008 67 0.039
urogenital system development GO:0001655 261 0.039
positive regulation of cellular protein catabolic process GO:1903364 34 0.038
regulation of t cell mediated immunity GO:0002709 34 0.038
cellular response to external stimulus GO:0071496 88 0.038
negative regulation of cell proliferation GO:0008285 296 0.038
acute phase response GO:0006953 10 0.038
regulation of peptidase activity GO:0052547 96 0.038
regulation of secretion GO:0051046 274 0.037
protein catabolic process GO:0030163 221 0.037
ear development GO:0043583 200 0.037
response to organic cyclic compound GO:0014070 198 0.037
cellular response to starvation GO:0009267 57 0.036
establishment of protein localization to organelle GO:0072594 118 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
respiratory burst GO:0045730 8 0.035
zymogen activation GO:0031638 41 0.035
defense response to gram negative bacterium GO:0050829 28 0.035
translational initiation GO:0006413 24 0.034
divalent inorganic cation transport GO:0072511 178 0.034
purine nucleotide catabolic process GO:0006195 211 0.034
heterocycle catabolic process GO:0046700 280 0.034
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
cellular lipid metabolic process GO:0044255 323 0.033
i kappab kinase nf kappab signaling GO:0007249 85 0.033
hydrogen transport GO:0006818 35 0.033
stem cell differentiation GO:0048863 268 0.033
activation of immune response GO:0002253 138 0.032
natural killer cell mediated cytotoxicity GO:0042267 29 0.032
cellular modified amino acid metabolic process GO:0006575 63 0.032
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.032
regulation of t cell proliferation GO:0042129 92 0.032
proteasomal protein catabolic process GO:0010498 98 0.032
cellular response to lipid GO:0071396 145 0.032
energy derivation by oxidation of organic compounds GO:0015980 77 0.032
cellular ketone metabolic process GO:0042180 84 0.032
multicellular organism growth GO:0035264 161 0.031
nitric oxide metabolic process GO:0046209 25 0.031
regulation of ph GO:0006885 26 0.031
proton transport GO:0015992 35 0.031
digestive tract development GO:0048565 190 0.031
regulation of hydrolase activity GO:0051336 246 0.030
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.030
protein processing GO:0016485 163 0.030
amine metabolic process GO:0009308 45 0.030
chemotaxis GO:0006935 247 0.030
positive regulation of hydrolase activity GO:0051345 148 0.030
regulation of response to dna damage stimulus GO:2001020 34 0.030
regulation of reactive oxygen species metabolic process GO:2000377 40 0.030
regulation of cellular ph GO:0030641 12 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
osteoclast differentiation GO:0030316 62 0.028
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.028
monovalent inorganic cation homeostasis GO:0055067 33 0.028
regulation of removal of superoxide radicals GO:2000121 4 0.028
inflammatory response to wounding GO:0090594 4 0.028
response to organonitrogen compound GO:0010243 246 0.028
nucleocytoplasmic transport GO:0006913 139 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.028
purine containing compound metabolic process GO:0072521 311 0.027
response to epidermal growth factor GO:0070849 4 0.027
metencephalon development GO:0022037 89 0.027
angiogenesis GO:0001525 201 0.027
regulation of neuron death GO:1901214 134 0.027
protein oligomerization GO:0051259 67 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.027
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.027
regulation of kinase activity GO:0043549 249 0.026
activation of cysteine type endopeptidase activity GO:0097202 27 0.026
single organism nuclear import GO:1902593 95 0.026
cellular response to dna damage stimulus GO:0006974 207 0.026
nucleotide metabolic process GO:0009117 332 0.026
endocytosis GO:0006897 168 0.026
aromatic compound catabolic process GO:0019439 286 0.026
regulation of transferase activity GO:0051338 263 0.026
detection of stimulus GO:0051606 84 0.026
nitric oxide biosynthetic process GO:0006809 25 0.026
intracellular protein transport GO:0006886 204 0.026
neuron death GO:0070997 154 0.025
regulation of lymphocyte activation GO:0051249 240 0.025
regulation of protein binding GO:0043393 60 0.025
exocytosis GO:0006887 121 0.025
tissue homeostasis GO:0001894 115 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
nuclear import GO:0051170 95 0.025
myeloid leukocyte activation GO:0002274 83 0.025
regulation of intracellular ph GO:0051453 11 0.025
interleukin 1 production GO:0032612 31 0.025
extrinsic apoptotic signaling pathway GO:0097191 126 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
negative regulation of apoptotic signaling pathway GO:2001234 104 0.024
inorganic ion import into cell GO:0099587 4 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
positive regulation of proteolysis GO:0045862 85 0.024
hemoglobin metabolic process GO:0020027 13 0.024
Zebrafish
glycosyl compound metabolic process GO:1901657 246 0.024
regulation of anatomical structure size GO:0090066 178 0.024
muscle system process GO:0003012 141 0.024
regulation of homeostatic process GO:0032844 182 0.023
positive regulation of secretion by cell GO:1903532 114 0.023
ph reduction GO:0045851 8 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
positive regulation of bone remodeling GO:0046852 13 0.023
positive regulation of kinase activity GO:0033674 155 0.023
regulation of protein kinase activity GO:0045859 232 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
protein modification by small protein conjugation GO:0032446 187 0.023
steroid metabolic process GO:0008202 119 0.023
cognition GO:0050890 149 0.023
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
cellular response to x ray GO:0071481 2 0.022
negative regulation of immune system process GO:0002683 209 0.022
leukocyte homeostasis GO:0001776 79 0.022
heart contraction GO:0060047 93 0.022
regulation of protein catabolic process GO:0042176 108 0.022
lung development GO:0030324 164 0.022
nuclear transport GO:0051169 139 0.022
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
leukocyte mediated cytotoxicity GO:0001909 62 0.022
locomotory behavior GO:0007626 195 0.022
interleukin 17 production GO:0032620 11 0.021
regulation of membrane potential GO:0042391 192 0.021
skeletal muscle organ development GO:0060538 163 0.021
male gamete generation GO:0048232 285 0.021
phagocytosis GO:0006909 66 0.021
photoreceptor cell differentiation GO:0046530 52 0.021
zinc ion transport GO:0006829 12 0.021
nuclear division GO:0000280 158 0.021
regulation of cell migration GO:0030334 219 0.021
response to oxygen radical GO:0000305 16 0.021
peptide metabolic process GO:0006518 46 0.021
regulation of proteolysis GO:0030162 164 0.021
forebrain development GO:0030900 302 0.021
cell type specific apoptotic process GO:0097285 268 0.021
regulation of t cell differentiation GO:0045580 83 0.021
cell fate commitment GO:0045165 210 0.021
carbohydrate metabolic process GO:0005975 230 0.020
calcium ion transport GO:0006816 159 0.020
negative regulation of homeostatic process GO:0032845 71 0.020
regulation of blood pressure GO:0008217 93 0.020
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.020
positive regulation of endocytosis GO:0045807 42 0.020
positive regulation of phagocytosis engulfment GO:0060100 3 0.020
response to decreased oxygen levels GO:0036293 59 0.020
regulation of intracellular transport GO:0032386 159 0.020
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.020
sequestering of metal ion GO:0051238 19 0.020
response to steroid hormone GO:0048545 56 0.020
adult behavior GO:0030534 135 0.020
maintenance of location GO:0051235 89 0.019
response to arsenic containing substance GO:0046685 5 0.019
body fluid secretion GO:0007589 53 0.019
organic acid biosynthetic process GO:0016053 86 0.019
respiratory system development GO:0060541 190 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
macrophage activation GO:0042116 27 0.019
glucose transport GO:0015758 56 0.019
nucleoside catabolic process GO:0009164 206 0.019
mitochondrion organization GO:0007005 134 0.019
wound healing involved in inflammatory response GO:0002246 4 0.019
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway GO:0002488 2 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
multi multicellular organism process GO:0044706 109 0.019
synaptic transmission GO:0007268 329 0.019
visual perception GO:0007601 52 0.019
defense response to other organism GO:0098542 197 0.019
exosomal secretion GO:1990182 1 0.018
regulation of endocytosis GO:0030100 69 0.018
peptide transport GO:0015833 133 0.018
regulation of lipid metabolic process GO:0019216 118 0.018
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.018
positive regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902231 6 0.018
regulation of glucose metabolic process GO:0010906 60 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
neuron apoptotic process GO:0051402 142 0.018
anatomical structure homeostasis GO:0060249 145 0.018
nucleoside metabolic process GO:0009116 246 0.018
protein import into nucleus translocation GO:0000060 12 0.018
cerebellar purkinje cell layer development GO:0021680 26 0.018
amide transport GO:0042886 138 0.018
positive regulation of leukocyte proliferation GO:0070665 73 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
fatty acid metabolic process GO:0006631 121 0.018
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
positive regulation of hormone secretion GO:0046887 38 0.018
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.017
sterol homeostasis GO:0055092 45 0.017
regulation of transmembrane transport GO:0034762 128 0.017
hormone secretion GO:0046879 128 0.017
cellular response to oxygen radical GO:0071450 14 0.017
antigen processing and presentation of exogenous peptide antigen via mhc class i GO:0042590 6 0.017
mapk cascade GO:0000165 281 0.017
regulation of lymphocyte proliferation GO:0050670 117 0.016
lipid catabolic process GO:0016042 69 0.016
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.016
organophosphate catabolic process GO:0046434 232 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
positive regulation of secretion GO:0051047 130 0.016
regulation of myeloid cell differentiation GO:0045637 96 0.016
wnt signaling pathway GO:0016055 188 0.016
response to reactive oxygen species GO:0000302 56 0.016
alpha beta t cell activation involved in immune response GO:0002287 31 0.016
positive regulation of growth GO:0045927 104 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
lipid homeostasis GO:0055088 63 0.016
atp metabolic process GO:0046034 75 0.016
fibrinolysis GO:0042730 3 0.016
regulation of cellular component size GO:0032535 121 0.016
regulation of peptide hormone secretion GO:0090276 75 0.016
glucan metabolic process GO:0044042 32 0.016
tissue remodeling GO:0048771 102 0.015
regulation of cell cycle GO:0051726 281 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
neuron projection guidance GO:0097485 141 0.015
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap dependent GO:0002485 3 0.015
intracellular ph reduction GO:0051452 6 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
regulation of cardiac muscle cell membrane potential GO:0086036 3 0.015
response to superoxide GO:0000303 16 0.015
basic amino acid transport GO:0015802 6 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
peptide secretion GO:0002790 114 0.014
regulation of cysteine type endopeptidase activity GO:2000116 65 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
carbohydrate homeostasis GO:0033500 128 0.014
action potential GO:0001508 78 0.014
negative regulation of cell activation GO:0050866 111 0.014
epidermis development GO:0008544 187 0.014
gliogenesis GO:0042063 141 0.014
intracellular mrna localization GO:0008298 4 0.014
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.014
response to nicotine GO:0035094 6 0.014
regulation of cellular protein catabolic process GO:1903362 61 0.014
mitotic cell cycle GO:0000278 195 0.014
neural tube formation GO:0001841 108 0.014
b cell differentiation GO:0030183 78 0.014
phospholipid metabolic process GO:0006644 87 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
alcohol metabolic process GO:0006066 116 0.014
cellular response to prostaglandin stimulus GO:0071379 2 0.014
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
sterol metabolic process GO:0016125 58 0.014
regulation of neuron differentiation GO:0045664 281 0.014
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.014
neural tube closure GO:0001843 90 0.013
lipid transport GO:0006869 98 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
regulation of receptor activity GO:0010469 41 0.013
negative regulation of neuron death GO:1901215 98 0.013
monosaccharide transport GO:0015749 58 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
response to nutrient levels GO:0031667 109 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
sensory perception of light stimulus GO:0050953 54 0.013
acylglycerol metabolic process GO:0006639 55 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
embryonic epithelial tube formation GO:0001838 130 0.013

Slc40a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.659
Human
inherited metabolic disorder DOID:655 0 0.659
Human
metal metabolism disorder DOID:896 0 0.659
Human
immune system disease DOID:2914 0 0.559
disease of anatomical entity DOID:7 0 0.559
anemia DOID:2355 0 0.559
hematopoietic system disease DOID:74 0 0.559
normocytic anemia DOID:720 0 0.357
acquired metabolic disease DOID:0060158 0 0.245
integumentary system disease DOID:16 0 0.201
central nervous system disease DOID:331 0 0.184
nervous system disease DOID:863 0 0.184
disease of mental health DOID:150 0 0.160
skin disease DOID:37 0 0.081
dementia DOID:1307 0 0.077
alzheimer s disease DOID:10652 0 0.077
tauopathy DOID:680 0 0.077
neurodegenerative disease DOID:1289 0 0.077
cognitive disorder DOID:1561 0 0.077
musculoskeletal system disease DOID:17 0 0.023
connective tissue disease DOID:65 0 0.023
hemolytic anemia DOID:583 0 0.022
porphyria DOID:13268 0 0.020
acute porphyria DOID:3133 0 0.016
cardiovascular system disease DOID:1287 0 0.015