|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.872
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.792
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.698
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.653
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.615
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.608
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.599
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.589
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.579
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.546
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.533
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.530
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.499
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.498
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.488
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.485
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.468
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.445
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.444
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.437
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.430
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.418
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.411
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.402
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.398
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.395
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.388
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.382
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.374
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.363
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.361
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.356
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.355
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.349
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.347
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.343
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.342
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.306
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.304
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.303
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.301
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.290
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.282
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.272
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.267
|
Mouse |
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.258
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.255
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.247
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.245
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.241
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.233
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.232
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.232
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.232
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.230
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.226
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.224
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.222
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.218
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.217
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.214
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.214
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.214
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.207
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.205
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.203
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.202
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.201
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.201
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.200
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.199
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.199
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.198
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.197
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.191
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.188
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.186
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.186
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.186
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.186
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.185
|
|
|
|
negative regulation of rho protein signal transduction
|
GO:0035024 |
7 |
0.177
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.172
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.171
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.167
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.166
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.166
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.165
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.165
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.163
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.162
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.159
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.157
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.156
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.156
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.155
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.155
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.155
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.154
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.150
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.150
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.149
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.146
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.145
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.141
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.141
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.138
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.137
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.136
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.136
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.136
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.134
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.134
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.133
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.132
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.130
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.129
|
|
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.129
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.128
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.128
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.127
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.127
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.127
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.127
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.125
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.125
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.124
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.124
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.123
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.123
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.122
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.122
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.122
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.122
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.120
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.120
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.119
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.118
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.118
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.118
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.118
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.117
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.116
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.115
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.115
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.114
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.113
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.113
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.113
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.112
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.111
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.111
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.111
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.111
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.111
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.110
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.110
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.109
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.109
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.107
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.106
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.106
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.106
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.106
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.105
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.105
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.105
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.104
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.104
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.104
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.102
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.101
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
4 |
0.101
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.100
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.099
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.099
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.098
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.098
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.098
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.097
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.097
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.097
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.097
|
|
|
|
microglia development
|
GO:0014005 |
2 |
0.097
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.097
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.096
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.096
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.095
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.094
|
|
|
|
substrate dependent cell migration
|
GO:0006929 |
18 |
0.094
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.093
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.093
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.093
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.093
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.093
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.092
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.092
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.091
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.091
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.091
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.091
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.091
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.089
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.089
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.089
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.089
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.089
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.089
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.088
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.088
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.088
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.087
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.087
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.087
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.086
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.085
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.085
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.085
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.084
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.084
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.084
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.083
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.083
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.083
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.082
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.082
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.082
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.082
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.081
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.081
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.080
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.080
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.080
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.080
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.079
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.079
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.079
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.078
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.078
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.077
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.077
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.077
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.076
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.076
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.076
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.076
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.076
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.075
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.075
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.074
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.074
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.074
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.073
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.073
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.073
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.073
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.073
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.072
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.071
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.070
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.070
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.070
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
30 |
0.069
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.068
|
|
|
|
dendritic spine organization
|
GO:0097061 |
26 |
0.068
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.068
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.068
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.068
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.068
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.067
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.067
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
18 |
0.067
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.066
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.065
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.065
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.064
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.064
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.064
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.063
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.063
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.063
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.063
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.062
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.062
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.062
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.062
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.062
|
|
|
|
cell cell adhesion via plasma membrane adhesion molecules
|
GO:0098742 |
40 |
0.061
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.061
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.061
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.061
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.061
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.061
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.060
|
|
|
|
regulation of natural killer cell activation
|
GO:0032814 |
22 |
0.059
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.059
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.059
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.059
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.059
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.059
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.059
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.058
|
|
|
|
regulation of osteoblast proliferation
|
GO:0033688 |
15 |
0.058
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.057
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.057
|
|
|
|
purinergic nucleotide receptor signaling pathway
|
GO:0035590 |
3 |
0.057
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.057
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.057
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.056
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.055
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.055
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.055
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.054
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.054
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.053
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.053
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.053
|
|
|
|
cd8 positive alpha beta t cell proliferation
|
GO:0035740 |
1 |
0.053
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.053
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.053
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.053
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.052
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.052
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.052
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.052
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.052
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.051
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.050
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.050
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.050
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.050
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.050
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.050
|
Mouse |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.049
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.049
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.049
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.049
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.049
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.049
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.049
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.049
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.049
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.048
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.048
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
20 |
0.047
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.047
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.047
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.047
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.047
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.046
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.046
|
|
|
|
epidermal growth factor receptor signaling pathway via i kappab kinase nf kappab cascade
|
GO:0038168 |
1 |
0.046
|
|
|
|
activation of rac gtpase activity
|
GO:0032863 |
2 |
0.046
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.046
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.046
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.046
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.046
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.045
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.045
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.045
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.045
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.045
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.044
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.044
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.044
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.044
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.044
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.044
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.044
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.044
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.044
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.044
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.044
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.044
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.044
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.044
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.043
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.043
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.042
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.042
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.042
|
|
|
|
lamellipodium organization
|
GO:0097581 |
29 |
0.042
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.042
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.042
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.042
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.042
|
Mouse |
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.042
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.042
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.042
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.041
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.041
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.041
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.041
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
26 |
0.041
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.041
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.040
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.040
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.040
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.040
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.040
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.039
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.039
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.039
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.039
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.039
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.039
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.039
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
2 |
0.039
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.039
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.039
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.039
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.039
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.039
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.039
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.038
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.038
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.038
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.038
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.038
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.038
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.038
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.038
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.038
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.037
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.037
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.037
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.037
|
|
|
|
post embryonic organ development
|
GO:0048569 |
17 |
0.037
|
Mouse |
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.037
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.037
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.037
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.037
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.037
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.037
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.037
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.037
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.036
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.036
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.036
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.036
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.035
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.035
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.035
|
|
|
|
blood vessel remodeling
|
GO:0001974 |
33 |
0.035
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.035
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.034
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.034
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.034
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.034
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.034
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.034
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.034
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.034
|
|
|
|
regulation of toll like receptor 9 signaling pathway
|
GO:0034163 |
3 |
0.034
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.034
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.034
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.033
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.033
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.033
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.033
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.033
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.033
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.033
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.033
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.033
|
|
|
|
memory
|
GO:0007613 |
58 |
0.033
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.032
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.032
|
|
|
|
regulation of intestinal epithelial structure maintenance
|
GO:0060730 |
1 |
0.032
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.032
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.032
|
|
|
|
superoxide metabolic process
|
GO:0006801 |
27 |
0.032
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
26 |
0.031
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.031
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.031
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.031
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.031
|
|
|
|
macrophage chemotaxis
|
GO:0048246 |
14 |
0.031
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.031
|
|
|
|
face development
|
GO:0060324 |
38 |
0.030
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.030
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.030
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.030
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.030
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.030
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.030
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.030
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.029
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.029
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.029
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.029
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.029
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.029
|
|
