Mus musculus

278 known processes

Akt2

thymoma viral proto-oncogene 2

(Aliases: AW554154,MGC14031,PKB,2410016A19Rik,PKBbeta)

Akt2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of fatty acid oxidation GO:0046322 5 0.539
regulation of fatty acid beta oxidation GO:0031998 1 0.513
Human
regulation of ral gtpase activity GO:0032315 4 0.441
positive regulation of protein targeting to membrane GO:0090314 7 0.383
organic acid catabolic process GO:0016054 51 0.377
Human
plasma membrane long chain fatty acid transport GO:0015911 1 0.351
Human
fatty acid transmembrane transport GO:1902001 1 0.347
Human
monocarboxylic acid catabolic process GO:0072329 27 0.332
Human
fatty acid oxidation GO:0019395 28 0.328
Human
positive regulation of interleukin 5 secretion GO:2000664 1 0.321
Mouse
endomembrane system organization GO:0010256 147 0.304
mitochondrion organization GO:0007005 134 0.303
Mouse
lipid modification GO:0030258 65 0.261
Human
small molecule catabolic process GO:0044282 71 0.239
Human
interleukin 10 secretion GO:0072608 4 0.220
Mouse
ral protein signal transduction GO:0032484 2 0.217
leukocyte differentiation GO:0002521 342 0.216
Mouse
regulation of interleukin 10 secretion GO:2001179 4 0.210
Mouse
cellular lipid catabolic process GO:0044242 52 0.210
Human
t helper 2 cell activation GO:0035712 2 0.184
Mouse
multicellular organism growth GO:0035264 161 0.179
Fly
glucose homeostasis GO:0042593 128 0.174
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.172
carboxylic acid catabolic process GO:0046395 51 0.160
Human
organic acid transport GO:0015849 101 0.159
Human
positive regulation of interleukin 13 secretion GO:2000667 1 0.157
Mouse
carbohydrate metabolic process GO:0005975 230 0.155
Human Mouse
protein modification by small protein conjugation GO:0032446 187 0.147
Mouse
oxidation reduction process GO:0055114 342 0.144
Human Mouse
cellular lipid metabolic process GO:0044255 323 0.143
Human
fatty acid catabolic process GO:0009062 25 0.138
Human
regulation of protein maturation GO:1903317 96 0.137
Mouse Rat
positive regulation of neuron projection regeneration GO:0070572 2 0.137
Fly
plasma membrane organization GO:0007009 90 0.133
monocarboxylic acid transport GO:0015718 44 0.132
Human
positive regulation of t helper 2 cell activation GO:2000570 2 0.129
Mouse
interleukin 5 secretion GO:0072603 2 0.128
Mouse
cellular amino acid metabolic process GO:0006520 103 0.128
protein modification by small protein conjugation or removal GO:0070647 207 0.124
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 65 0.124
Mouse Rat
inflammatory response GO:0006954 244 0.123
Mouse
circadian rhythm GO:0007623 114 0.122
Fly
protein localization to membrane GO:0072657 108 0.120
positive regulation of interleukin 10 secretion GO:2001181 1 0.120
Mouse
cellular response to peptide hormone stimulus GO:0071375 92 0.118
cytokine production GO:0001816 319 0.117
Mouse
synaptic transmission GO:0007268 329 0.114
Mouse Fly
positive regulation of apoptotic process GO:0043065 217 0.114
Mouse
monosaccharide metabolic process GO:0005996 106 0.113
Human Mouse
regulation of insulin receptor signaling pathway GO:0046626 21 0.113
Mouse
negative regulation of release of cytochrome c from mitochondria GO:0090201 6 0.111
Mouse
regulation of ral protein signal transduction GO:0032485 4 0.110
energy derivation by oxidation of organic compounds GO:0015980 77 0.104
Human Mouse
activation of ral gtpase activity GO:0032859 3 0.104
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.104
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.103
Fly
immune effector process GO:0002252 321 0.103
Mouse
negative regulation of molecular function GO:0044092 258 0.101
Mouse Rat
t helper 2 cell cytokine production GO:0035745 4 0.100
Mouse
regulation of mitochondrion organization GO:0010821 27 0.100
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.099
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.097
heterocycle catabolic process GO:0046700 280 0.097
negative regulation of fatty acid metabolic process GO:0045922 10 0.097
negative regulation of cellular amine metabolic process GO:0033239 1 0.097
negative regulation of protein processing GO:0010955 79 0.095
Mouse Rat
apoptotic signaling pathway GO:0097190 306 0.094
Mouse
embryonic placenta development GO:0001892 98 0.094
Mouse
cytokine biosynthetic process GO:0042089 68 0.093
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.093
membrane organization GO:0061024 245 0.092
regulation of t cell differentiation GO:0045580 83 0.092
Mouse
lymphocyte differentiation GO:0030098 242 0.091
Mouse
regulation of response to wounding GO:1903034 189 0.090
Mouse Fly
glucose metabolic process GO:0006006 92 0.090
Human Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.088
cellular carbohydrate metabolic process GO:0044262 119 0.088
Human Mouse
nucleotide catabolic process GO:0009166 217 0.088
fatty acid metabolic process GO:0006631 121 0.084
Human
cellular response to insulin stimulus GO:0032869 78 0.084
regulation of secretion by cell GO:1903530 249 0.083
Mouse
anion transport GO:0006820 177 0.083
Human
alpha beta t cell differentiation GO:0046632 69 0.082
Mouse
action potential GO:0001508 78 0.081
modification dependent protein catabolic process GO:0019941 133 0.081
Mouse
amine metabolic process GO:0009308 45 0.081
lipid transport GO:0006869 98 0.080
Human
positive regulation of ral gtpase activity GO:0032852 4 0.080
leukocyte mediated immunity GO:0002443 174 0.080
Mouse
positive regulation of growth GO:0045927 104 0.079
Fly
regulation of interleukin 5 secretion GO:2000662 2 0.079
Mouse
interleukin 13 secretion GO:0072611 2 0.078
Mouse
multicellular organismal signaling GO:0035637 91 0.077
regulation of cellular amine metabolic process GO:0033238 20 0.076
t cell differentiation GO:0030217 174 0.076
Mouse
positive regulation of programmed cell death GO:0043068 218 0.073
Mouse
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.072
Mouse
regulation of endopeptidase activity GO:0052548 89 0.072
Mouse Rat
carbohydrate homeostasis GO:0033500 128 0.072
Mouse
lymphocyte mediated immunity GO:0002449 139 0.070
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.070
Mouse Rat
leukocyte activation involved in immune response GO:0002366 126 0.070
Mouse
regulation of lipid catabolic process GO:0050994 15 0.069
Human
protein targeting to membrane GO:0006612 20 0.069
positive regulation of cellular amine metabolic process GO:0033240 5 0.069
cellular response to granulocyte macrophage colony stimulating factor stimulus GO:0097011 3 0.069
Mouse
cytoplasmic mrna processing body assembly GO:0033962 6 0.069
Yeast
carbohydrate biosynthetic process GO:0016051 74 0.069
Human
t cell activation GO:0042110 289 0.068
Mouse
neuronal action potential GO:0019228 54 0.068
cell cycle g1 s phase transition GO:0044843 57 0.068
cellular response to peptide GO:1901653 92 0.067
cellular response to epidermal growth factor stimulus GO:0071364 4 0.067
Mouse
cellular amine metabolic process GO:0044106 44 0.067
organic anion transport GO:0015711 137 0.067
Human
negative regulation of protein metabolic process GO:0051248 282 0.067
Mouse Rat
regulation of lymphocyte differentiation GO:0045619 107 0.066
Mouse
membrane fusion GO:0061025 38 0.066
negative regulation of response to wounding GO:1903035 77 0.066
Mouse
regulation of glucose transport GO:0010827 32 0.064
cation transport GO:0006812 399 0.064
Mouse Rat
cd4 positive alpha beta t cell activation GO:0035710 45 0.063
Mouse
regulation of cell projection organization GO:0031344 206 0.063
Mouse Fly
negative regulation of endopeptidase activity GO:0010951 44 0.063
Mouse Rat
regulation of hydrolase activity GO:0051336 246 0.062
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.062
Mouse
alpha beta t cell activation involved in immune response GO:0002287 31 0.062
Mouse
protein transmembrane transport GO:0071806 8 0.062
response to organonitrogen compound GO:0010243 246 0.061
negative regulation of intracellular signal transduction GO:1902532 167 0.061
cytokine metabolic process GO:0042107 71 0.061
Mouse
single organism cell adhesion GO:0098602 156 0.060
Mouse
negative regulation of fatty acid transport GO:2000192 1 0.059
Human
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.059
Mouse
insulin receptor signaling pathway GO:0008286 49 0.059
regulation of cellular ketone metabolic process GO:0010565 66 0.059
Human
adaptive immune response GO:0002250 155 0.059
Mouse
regulation of protein processing GO:0070613 96 0.059
Mouse Rat
regulation of reactive oxygen species metabolic process GO:2000377 40 0.058
lipid oxidation GO:0034440 29 0.058
Human
mrna 3 end processing GO:0031124 16 0.058
Yeast
cytoplasmic transport GO:0016482 234 0.058
nucleoside catabolic process GO:0009164 206 0.058
regulation of membrane potential GO:0042391 192 0.057
regulation of mrna catabolic process GO:0061013 6 0.057
Yeast
negative regulation of mitochondrion organization GO:0010823 9 0.057
Mouse
negative regulation of peptidase activity GO:0010466 46 0.057
Mouse Rat
g1 s transition of mitotic cell cycle GO:0000082 57 0.056
regulation of apoptotic signaling pathway GO:2001233 197 0.056
Mouse
cell type specific apoptotic process GO:0097285 268 0.056
cell adhesion GO:0007155 329 0.055
Mouse
negative regulation of lipid metabolic process GO:0045833 30 0.055
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.055
Mouse
negative regulation of cell activation GO:0050866 111 0.054
Mouse
establishment of protein localization to membrane GO:0090150 54 0.054
apoptotic mitochondrial changes GO:0008637 48 0.054
Mouse
nitrogen compound transport GO:0071705 271 0.054
positive regulation of immune effector process GO:0002699 107 0.054
Mouse
regulation of ion transport GO:0043269 215 0.054
Human Mouse Rat
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.053
response to peptide hormone GO:0043434 127 0.053
lipid biosynthetic process GO:0008610 179 0.053
cellular response to organonitrogen compound GO:0071417 145 0.053
positive regulation of cell activation GO:0050867 158 0.052
Mouse
response to epidermal growth factor GO:0070849 4 0.052
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.052
glycogen cell differentiation involved in embryonic placenta development GO:0060709 1 0.052
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.052
Human
regulation of cellular component biogenesis GO:0044087 181 0.051
Mouse Fly
negative regulation of phosphorylation GO:0042326 166 0.051
Mouse
response to insulin GO:0032868 100 0.051
energy reserve metabolic process GO:0006112 39 0.051
Human Mouse
carbohydrate transport GO:0008643 62 0.050
t cell homeostasis GO:0043029 35 0.049
ras protein signal transduction GO:0007265 77 0.049
homeostasis of number of cells GO:0048872 210 0.049
negative regulation of synapse assembly GO:0051964 3 0.048
Fly
intracellular protein transport GO:0006886 204 0.048
regulation of glucose metabolic process GO:0010906 60 0.048
Human
regulation of cellular catabolic process GO:0031329 242 0.047
cellular response to hormone stimulus GO:0032870 150 0.047
positive regulation of lipid metabolic process GO:0045834 40 0.047
Human
response to extracellular stimulus GO:0009991 127 0.047
Mouse Rat
cellular nitrogen compound catabolic process GO:0044270 280 0.047
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.047
Mouse
negative regulation of cysteine type endopeptidase activity GO:2000117 22 0.046
Mouse Rat
purine nucleotide metabolic process GO:0006163 302 0.046
macromolecule catabolic process GO:0009057 281 0.046
Yeast Mouse
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.046
Mouse
male gamete generation GO:0048232 285 0.046
glucan biosynthetic process GO:0009250 14 0.046
Human
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.046
Mouse
establishment of protein localization to plasma membrane GO:0090002 34 0.045
Mouse
negative regulation of cellular catabolic process GO:0031330 47 0.045
glucose import in response to insulin stimulus GO:0044381 8 0.045
monocarboxylic acid metabolic process GO:0032787 191 0.045
Human
production of molecular mediator of immune response GO:0002440 103 0.045
Mouse
protein localization to plasma membrane GO:0072659 57 0.044
positive regulation of lymphocyte differentiation GO:0045621 61 0.044
Mouse
protein ubiquitination GO:0016567 171 0.044
Mouse
response to peptide GO:1901652 136 0.044
positive regulation of leukocyte mediated immunity GO:0002705 70 0.044
Mouse
regulation of hormone levels GO:0010817 211 0.044
vesicle organization GO:0016050 60 0.044
regulation of fatty acid metabolic process GO:0019217 28 0.043
Human
response to uv a GO:0070141 1 0.043
anatomical structure maturation GO:0071695 49 0.043
Mouse
cellular glucan metabolic process GO:0006073 32 0.043
Human Mouse
hexose metabolic process GO:0019318 98 0.043
Human Mouse
positive regulation of secretion by cell GO:1903532 114 0.043
Mouse
axon ensheathment GO:0008366 76 0.042
polysaccharide metabolic process GO:0005976 39 0.042
Human Mouse
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.042
Mouse
eye photoreceptor cell development GO:0042462 31 0.042
Mouse
interleukin 17 production GO:0032620 11 0.042
Mouse
regulation of body fluid levels GO:0050878 162 0.042
Mouse
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 12 0.042
Yeast
placenta development GO:0001890 140 0.042
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.042
myelination GO:0042552 74 0.042
negative regulation of protein modification process GO:0031400 163 0.041
Mouse
myeloid cell differentiation GO:0030099 233 0.041
cellular homeostasis GO:0019725 240 0.040
positive regulation of vasoconstriction GO:0045907 4 0.040
positive regulation of neuron projection development GO:0010976 79 0.040
Fly
immunoglobulin mediated immune response GO:0016064 69 0.040
Mouse
positive regulation of t cell activation GO:0050870 101 0.040
Mouse
lipid catabolic process GO:0016042 69 0.040
Human
single organismal cell cell adhesion GO:0016337 131 0.040
Mouse
monosaccharide transport GO:0015749 58 0.040
regulation of cytokine biosynthetic process GO:0042035 59 0.040
Mouse
nucleotide metabolic process GO:0009117 332 0.040
lipid storage GO:0019915 36 0.040
Fly
amide transport GO:0042886 138 0.039
regulation of carbohydrate biosynthetic process GO:0043255 40 0.039
Human
organelle fusion GO:0048284 28 0.039
protein maturation GO:0051604 176 0.039
Mouse Rat
peptidyl amino acid modification GO:0018193 336 0.039
Mouse Rat Worm
regulation of leukocyte mediated immunity GO:0002703 104 0.038
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.038
Mouse
regulation of alpha beta t cell differentiation GO:0046637 35 0.038
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.038
Mouse
cellular polysaccharide metabolic process GO:0044264 38 0.038
Human Mouse
regulation of cytokine production involved in immune response GO:0002718 26 0.038
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.038
Human
regulation of lymphocyte mediated immunity GO:0002706 84 0.038
Mouse
glucose import GO:0046323 32 0.038
regulation of mapk cascade GO:0043408 248 0.038
positive regulation of protein phosphorylation GO:0001934 242 0.037
positive regulation of t cell differentiation GO:0045582 52 0.037
Mouse
positive regulation of nitric oxide synthase activity GO:0051000 2 0.037
positive regulation of secretion GO:0051047 130 0.037
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.037
purine nucleoside metabolic process GO:0042278 241 0.036
regulation of ras protein signal transduction GO:0046578 114 0.036
positive regulation of protein modification process GO:0031401 299 0.036
positive regulation of lymphocyte activation GO:0051251 140 0.036
Mouse
negative regulation of filopodium assembly GO:0051490 2 0.036
Mouse
hexose transport GO:0008645 56 0.036
negative regulation of phosphorus metabolic process GO:0010563 184 0.036
Mouse
labyrinthine layer development GO:0060711 49 0.036
Mouse
protein targeting GO:0006605 143 0.035
regulation of cellular response to stress GO:0080135 159 0.035
Fly
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.035
Mouse
negative regulation of growth GO:0045926 99 0.035
Fly
syncytium formation GO:0006949 43 0.035
Fly
cellular macromolecule catabolic process GO:0044265 206 0.035
Yeast Mouse
regulation of establishment of protein localization GO:0070201 181 0.035
positive regulation of response to wounding GO:1903036 66 0.035
Fly
lymphocyte proliferation GO:0046651 164 0.035
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.035
nucleoside triphosphate metabolic process GO:0009141 230 0.034
regulation of protein catabolic process GO:0042176 108 0.034
Mouse
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.034
Mouse
regulation of cell migration GO:0030334 219 0.034
Rat
regulation of t cell activation GO:0050863 170 0.034
Mouse
developmental maturation GO:0021700 193 0.034
Mouse
regulation of blood coagulation GO:0030193 28 0.034
Mouse
regulation of organelle organization GO:0033043 289 0.034
negative regulation of phosphate metabolic process GO:0045936 184 0.034
Mouse
positive regulation of cytokine biosynthetic process GO:0042108 40 0.034
Mouse
regulation of transmembrane transport GO:0034762 128 0.034
Human
germ cell development GO:0007281 185 0.033
Mouse Fly
positive regulation of glucose transport GO:0010828 16 0.033
release of cytochrome c from mitochondria GO:0001836 23 0.033
Mouse
regulation of actin filament based process GO:0032970 99 0.033
Mouse
ribonucleotide metabolic process GO:0009259 291 0.033
protein catabolic process GO:0030163 221 0.033
Mouse
rna catabolic process GO:0006401 29 0.033
Yeast
peptide transport GO:0015833 133 0.033
fat cell differentiation GO:0045444 160 0.033
fatty acid transport GO:0015908 28 0.032
Human
interleukin 2 biosynthetic process GO:0042094 15 0.032
Mouse
negative regulation of lipid catabolic process GO:0050995 6 0.032
response to oxidative stress GO:0006979 123 0.032
Fly
regulation of protein kinase activity GO:0045859 232 0.032
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.032
Mouse
regulation of cell size GO:0008361 72 0.032
Fly
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.032
Mouse
b cell activation GO:0042113 161 0.032
Mouse
b cell mediated immunity GO:0019724 71 0.032
Mouse
cytokine production involved in immune response GO:0002367 34 0.032
Mouse
regulation of lipid metabolic process GO:0019216 118 0.032
Human
spongiotrophoblast layer development GO:0060712 15 0.032
Mouse
regulation of t helper cell differentiation GO:0045622 14 0.031
Mouse
regulation of neuron differentiation GO:0045664 281 0.031
Mouse Fly
response to nutrient levels GO:0031667 109 0.031
Mouse Rat
regulation of leukocyte proliferation GO:0070663 121 0.031
Mouse
mapk cascade GO:0000165 281 0.031
rna processing GO:0006396 105 0.031
Yeast Rat
negative regulation of nervous system development GO:0051961 156 0.031
Fly
regulation of proteolysis GO:0030162 164 0.030
Mouse Rat
regulation of glucose import in response to insulin stimulus GO:2001273 8 0.030
translation GO:0006412 93 0.030
epidermis development GO:0008544 187 0.030
Mouse
sodium ion transport GO:0006814 73 0.030
Mouse Rat
aromatic compound catabolic process GO:0019439 286 0.030
organelle assembly GO:0070925 177 0.030
Yeast
positive regulation of protein kinase activity GO:0045860 144 0.030
protein import GO:0017038 101 0.030
regulation of t cell proliferation GO:0042129 92 0.030
Mouse
lymphocyte homeostasis GO:0002260 64 0.030
regulation of kinase activity GO:0043549 249 0.030
regulation of cellular component size GO:0032535 121 0.030
Mouse Fly
rna 3 end processing GO:0031123 20 0.030
Yeast
spermatogenesis GO:0007283 284 0.030
negative regulation of hydrolase activity GO:0051346 71 0.029
Mouse Rat
response to oxygen levels GO:0070482 62 0.029
ensheathment of neurons GO:0007272 76 0.029
positive regulation of sodium ion transport GO:0010765 13 0.029
Mouse Rat
negative regulation of proteolysis GO:0045861 74 0.029
Mouse Rat
positive regulation of interleukin 13 production GO:0032736 4 0.029
Mouse
regulation of cytokine production GO:0001817 266 0.029
Mouse
positive regulation of cell projection organization GO:0031346 95 0.029
Fly
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.029
Mouse
protein polymerization GO:0051258 57 0.029
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.029
myotube differentiation GO:0014902 105 0.029
Fly
hyaluronan metabolic process GO:0030212 4 0.028
nucleoside triphosphate catabolic process GO:0009143 205 0.028
sulfur compound metabolic process GO:0006790 100 0.028
t cell activation involved in immune response GO:0002286 43 0.028
Mouse
negative regulation of cellular component organization GO:0051129 194 0.028
Mouse Fly
mrna processing GO:0006397 63 0.028
Yeast
purine nucleotide catabolic process GO:0006195 211 0.028
regulation of cell growth GO:0001558 91 0.028
Fly
mitotic cell cycle GO:0000278 195 0.028
positive regulation of cytokine production GO:0001819 174 0.028
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.028
peptidyl tyrosine modification GO:0018212 145 0.028
Mouse
positive regulation of leukocyte proliferation GO:0070665 73 0.028
Mouse
ossification GO:0001503 216 0.028
Mouse
epithelial cell proliferation GO:0050673 174 0.027
regulation of interleukin 2 production GO:0032663 28 0.027
Mouse
positive regulation of proteolysis GO:0045862 85 0.027
Mouse
leukocyte homeostasis GO:0001776 79 0.027
peptidyl tyrosine phosphorylation GO:0018108 143 0.027
Mouse
negative regulation of cell projection organization GO:0031345 56 0.027
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.027
Mouse
regulation of system process GO:0044057 200 0.027
peptidyl serine phosphorylation GO:0018105 74 0.027
Mouse Rat Worm
regulation of actin cytoskeleton organization GO:0032956 84 0.026
Mouse
regulation of actin filament length GO:0030832 45 0.026
Mouse
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.026
Mouse
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.026
Rat
posttranscriptional regulation of gene expression GO:0010608 155 0.026
purine containing compound catabolic process GO:0072523 213 0.026
protein localization to organelle GO:0033365 185 0.026
positive regulation of intracellular protein transport GO:0090316 42 0.026
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
positive regulation of ion transport GO:0043270 65 0.026
Mouse Rat
regulation of protein localization GO:0032880 231 0.026
cellular response to growth factor stimulus GO:0071363 197 0.026
Mouse
blood coagulation GO:0007596 76 0.026
Mouse
positive regulation of alpha beta t cell activation GO:0046635 39 0.025
Mouse
cellular response to organic cyclic compound GO:0071407 87 0.025
Rat
sensory organ morphogenesis GO:0090596 242 0.025
Mouse
regulation of protein secretion GO:0050708 82 0.025
Mouse
establishment of protein localization to organelle GO:0072594 118 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
regulation of t helper 2 cell differentiation GO:0045628 8 0.025
Mouse
protein processing GO:0016485 163 0.025
Mouse Rat
regulation of myelination GO:0031641 20 0.025
Mouse
mitotic cell cycle process GO:1903047 159 0.025
t helper cell differentiation GO:0042093 28 0.025
Mouse
positive regulation of protein transport GO:0051222 93 0.025
nucleocytoplasmic transport GO:0006913 139 0.025
regulation of mrna 3 end processing GO:0031440 6 0.025
Yeast
innate immune response GO:0045087 157 0.024
regulation of glycogen metabolic process GO:0070873 13 0.024
Human
small gtpase mediated signal transduction GO:0007264 97 0.024
regulation of alpha beta t cell activation GO:0046634 53 0.024
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.024
Mouse
cellular chemical homeostasis GO:0055082 215 0.024
hormone secretion GO:0046879 128 0.024
regulation of cell projection assembly GO:0060491 38 0.024
Mouse
actin filament organization GO:0007015 113 0.024
Yeast Mouse
maternal process involved in female pregnancy GO:0060135 32 0.024
Mouse
lateral inhibition GO:0046331 1 0.024
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.024
Mouse
cytokine secretion GO:0050663 72 0.024
Mouse
blood circulation GO:0008015 195 0.024
autophagy GO:0006914 45 0.023
Yeast
response to organic cyclic compound GO:0014070 198 0.023
Mouse Rat
regulation of peptide transport GO:0090087 91 0.023
positive regulation of ras gtpase activity GO:0032320 65 0.023
maintenance of location GO:0051235 89 0.023
Fly
nuclear transcribed mrna catabolic process GO:0000956 16 0.023
Yeast
glycogen biosynthetic process GO:0005978 14 0.023
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
organophosphate catabolic process GO:0046434 232 0.022
nucleoside metabolic process GO:0009116 246 0.022
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.022
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.022
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.022
Mouse Rat
long chain fatty acid transport GO:0015909 15 0.022
Human
purine ribonucleotide metabolic process GO:0009150 290 0.022
positive regulation of cellular protein catabolic process GO:1903364 34 0.022
Mouse
nuclear transport GO:0051169 139 0.022
positive regulation of intracellular transport GO:0032388 70 0.022
regulation of glucose import GO:0046324 26 0.022
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.022
Mouse
regulation of carbohydrate metabolic process GO:0006109 75 0.022
Human
organonitrogen compound catabolic process GO:1901565 264 0.022
positive regulation of glucose import in response to insulin stimulus GO:2001275 5 0.022
regulation of homeostatic process GO:0032844 182 0.022
regulation of blood vessel size GO:0050880 56 0.022
negative regulation of transferase activity GO:0051348 85 0.021
mrna metabolic process GO:0016071 84 0.021
Yeast
purine containing compound metabolic process GO:0072521 311 0.021
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.021
Mouse
regulation of peptide hormone secretion GO:0090276 75 0.021
t cell differentiation involved in immune response GO:0002292 30 0.021
Mouse
insulin secretion GO:0030073 89 0.021
regulation of jnk cascade GO:0046328 62 0.021
positive regulation of cell development GO:0010720 237 0.021
Fly
microtubule cytoskeleton organization GO:0000226 157 0.021
Mouse
negative regulation of kinase activity GO:0033673 81 0.021
positive regulation of nucleotide metabolic process GO:0045981 114 0.021
skin development GO:0043588 220 0.021
Mouse
positive regulation of cell growth GO:0030307 33 0.021
Fly
rhythmic process GO:0048511 174 0.021
Fly
epithelial cell development GO:0002064 159 0.021
peptide hormone secretion GO:0030072 109 0.021
hair cycle GO:0042633 90 0.021
Mouse
modification dependent macromolecule catabolic process GO:0043632 133 0.021
Mouse
lymphocyte apoptotic process GO:0070227 54 0.020
positive regulation of neuron differentiation GO:0045666 141 0.020
Fly
glycerolipid metabolic process GO:0046486 122 0.020
regulation of defense response GO:0031347 233 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
glycoprotein metabolic process GO:0009100 116 0.020
glucose transport GO:0015758 56 0.020
multi multicellular organism process GO:0044706 109 0.020
Mouse
regulation of anatomical structure size GO:0090066 178 0.020
Mouse Fly
activation induced cell death of t cells GO:0006924 10 0.020
regulation of type 2 immune response GO:0002828 18 0.020
Mouse
positive regulation of kinase activity GO:0033674 155 0.020
negative regulation of cell adhesion GO:0007162 45 0.020
Mouse
leukocyte apoptotic process GO:0071887 71 0.020
myelination in peripheral nervous system GO:0022011 19 0.020
cell differentiation involved in embryonic placenta development GO:0060706 26 0.020
Mouse
response to radiation GO:0009314 165 0.020
polysaccharide biosynthetic process GO:0000271 20 0.019
Human
regulation of cell motility GO:2000145 236 0.019
Human Rat
regulation of cytokine secretion GO:0050707 61 0.019
Mouse
regulation of organ growth GO:0046620 61 0.019
Fly
regulation of synaptic plasticity GO:0048167 87 0.019
Fly
cell maturation GO:0048469 127 0.019
schwann cell development GO:0014044 22 0.019
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.019
Mouse
regulation of lipid biosynthetic process GO:0046890 54 0.019
positive regulation of interleukin 17 production GO:0032740 3 0.019
Mouse
oocyte axis specification GO:0007309 2 0.019
synapse assembly GO:0007416 56 0.019
Fly
compound eye development GO:0048749 1 0.019
response to decreased oxygen levels GO:0036293 59 0.019
negative regulation of mapk cascade GO:0043409 65 0.019
interleukin 2 production GO:0032623 33 0.019
Mouse
filopodium assembly GO:0046847 19 0.019
Mouse
peptide secretion GO:0002790 114 0.019
organ growth GO:0035265 117 0.019
Fly
regulation of tube size GO:0035150 57 0.018
lipid localization GO:0010876 126 0.018
Human Fly
maternal placenta development GO:0001893 20 0.018
Mouse

Akt2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.052
gastrointestinal system cancer DOID:3119 0 0.047
cancer DOID:162 0 0.047
organ system cancer DOID:0050686 0 0.047
breast cancer DOID:1612 0 0.036
thoracic cancer DOID:5093 0 0.036
central nervous system disease DOID:331 0 0.032
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
colon carcinoma DOID:1520 0 0.031
large intestine cancer DOID:5672 0 0.031
colon cancer DOID:219 0 0.031
intestinal cancer DOID:10155 0 0.031
colorectal cancer DOID:9256 0 0.031